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Network neighborhood for query Sequence : DCBD2_HUMAN

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DCBD2_HUMAN
SwissProt Accessions	Q96PD2, Q8N6M4, Q8TDX2	Gene names	DCBLD2, CLCP1, ESDN
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein) (CUB, LCCL and coagulation factor V/VIII-homology domains protein 1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

DCBD2_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	118	Target Neighborhood Hits	118	Shared Neighborhood Hits	118
SwissProt Accessions	Q96PD2, Q8N6M4, Q8TDX2	Gene names	DCBLD2, CLCP1, ESDN
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein) (CUB, LCCL and coagulation factor V/VIII-homology domains protein 1).

DCBD2_MOUSE
θ value	0 (rank : 2)	NC score	0.995624 (rank : 2)
Query Neighborhood Hits	118	Target Neighborhood Hits	113	Shared Neighborhood Hits	101
SwissProt Accessions	Q91ZV3, Q8BKI4	Gene names	Dcbld2, Esdn
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein).

DCBD1_HUMAN
θ value	6.7005e-96 (rank : 3)	NC score	0.947228 (rank : 3)
Query Neighborhood Hits	118	Target Neighborhood Hits	110	Shared Neighborhood Hits	89
SwissProt Accessions	Q8N8Z6, Q5H992, Q8IYK5, Q8N7L9, Q96NH2	Gene names	DCBLD1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

DCBD1_MOUSE
θ value	3.1488e-53 (rank : 4)	NC score	0.751220 (rank : 8)
Query Neighborhood Hits	118	Target Neighborhood Hits	89	Shared Neighborhood Hits	65
SwissProt Accessions	Q9D4J3, Q8R327, Q9D696	Gene names	Dcbld1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

EDIL3_HUMAN
θ value	6.17384e-33 (rank : 5)	NC score	0.497220 (rank : 36)
Query Neighborhood Hits	118	Target Neighborhood Hits	292	Shared Neighborhood Hits	44
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

EDIL3_MOUSE
θ value	1.37539e-32 (rank : 6)	NC score	0.488368 (rank : 37)
Query Neighborhood Hits	118	Target Neighborhood Hits	317	Shared Neighborhood Hits	41
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

MFGM_HUMAN
θ value	2.59387e-31 (rank : 7)	NC score	0.682518 (rank : 11)
Query Neighborhood Hits	118	Target Neighborhood Hits	150	Shared Neighborhood Hits	34
SwissProt Accessions	Q08431	Gene names	MFGE8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (HMFG) (Breast epithelial antigen BA46) (MFGM) [Contains: Lactadherin short form; Medin].

NRP2_HUMAN
θ value	1.85889e-29 (rank : 8)	NC score	0.834320 (rank : 5)
Query Neighborhood Hits	118	Target Neighborhood Hits	120	Shared Neighborhood Hits	87
SwissProt Accessions	O60462, O14820, O14821	Gene names	NRP2, VEGF165R2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

NRP2_MOUSE
θ value	5.40856e-29 (rank : 9)	NC score	0.835598 (rank : 4)
Query Neighborhood Hits	118	Target Neighborhood Hits	113	Shared Neighborhood Hits	87
SwissProt Accessions	O35375, O35373, O35374, O35376, O35377, O35378	Gene names	Nrp2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

MFGM_MOUSE
θ value	9.2256e-29 (rank : 10)	NC score	0.587284 (rank : 16)
Query Neighborhood Hits	118	Target Neighborhood Hits	233	Shared Neighborhood Hits	36
SwissProt Accessions	P21956, P97800, Q3TBN5, Q9R1X9, Q9WTS3	Gene names	Mfge8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (MFGM) (Sperm surface protein SP47) (MP47).

FA8_HUMAN
θ value	3.87602e-27 (rank : 11)	NC score	0.576457 (rank : 18)
Query Neighborhood Hits	118	Target Neighborhood Hits	112	Shared Neighborhood Hits	33
SwissProt Accessions	P00451	Gene names	F8, F8C
Domain Architecture
Description	Coagulation factor VIII precursor (Procoagulant component) (Antihemophilic factor) (AHF) [Contains: Factor VIIIa heavy chain, 200 kDa isoform; Factor VIIIa heavy chain, 92 kDa isoform; Factor VIII B chain; Factor VIIIa light chain].

FA8_MOUSE
θ value	3.87602e-27 (rank : 12)	NC score	0.576101 (rank : 19)
Query Neighborhood Hits	118	Target Neighborhood Hits	100	Shared Neighborhood Hits	32
SwissProt Accessions	Q06194	Gene names	F8, Cf8, F8c
Domain Architecture
Description	Coagulation factor VIII precursor (Procoagulant component).

NRP1_MOUSE
θ value	1.12775e-26 (rank : 13)	NC score	0.820927 (rank : 6)
Query Neighborhood Hits	118	Target Neighborhood Hits	120	Shared Neighborhood Hits	86
SwissProt Accessions	P97333	Gene names	Nrp1, Nrp
Domain Architecture
Description	Neuropilin-1 precursor (A5 protein).

FA5_HUMAN
θ value	1.47289e-26 (rank : 14)	NC score	0.584040 (rank : 17)
Query Neighborhood Hits	118	Target Neighborhood Hits	172	Shared Neighborhood Hits	34
SwissProt Accessions	P12259, Q14285, Q6UPU6	Gene names	F5
Domain Architecture
Description	Coagulation factor V precursor (Activated protein C cofactor) [Contains: Coagulation factor V heavy chain; Coagulation factor V light chain].

NRP1_HUMAN
θ value	2.51237e-26 (rank : 15)	NC score	0.820043 (rank : 7)
Query Neighborhood Hits	118	Target Neighborhood Hits	119	Shared Neighborhood Hits	87
SwissProt Accessions	O14786, O60461, Q96IH5	Gene names	NRP1, NRP, VEGF165R
Domain Architecture
Description	Neuropilin-1 precursor (Vascular endothelial cell growth factor 165 receptor) (CD304 antigen).

XLRS1_MOUSE
θ value	4.9032e-22 (rank : 16)	NC score	0.699684 (rank : 9)
Query Neighborhood Hits	118	Target Neighborhood Hits	32	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Z1L4	Gene names	Rs1, Rs1h, Xlrs1
Domain Architecture
Description	Retinoschisin precursor (X-linked juvenile retinoschisis protein homolog).

XLRS1_HUMAN
θ value	1.42661e-21 (rank : 17)	NC score	0.699333 (rank : 10)
Query Neighborhood Hits	118	Target Neighborhood Hits	32	Shared Neighborhood Hits	32
SwissProt Accessions	O15537	Gene names	RS1, XLRS1
Domain Architecture
Description	Retinoschisin precursor (X-linked juvenile retinoschisis protein).

CPXM2_HUMAN
θ value	3.07829e-16 (rank : 18)	NC score	0.440620 (rank : 45)
Query Neighborhood Hits	118	Target Neighborhood Hits	84	Shared Neighborhood Hits	31
SwissProt Accessions	Q8N436	Gene names	CPXM2
Domain Architecture
Description	Carboxypeptidase-like protein X2 precursor.

CPXM2_MOUSE
θ value	3.07829e-16 (rank : 19)	NC score	0.443774 (rank : 43)
Query Neighborhood Hits	118	Target Neighborhood Hits	58	Shared Neighborhood Hits	31
SwissProt Accessions	Q9D2L5, O54860, Q8VDQ4	Gene names	Cpxm2, Cpx2
Domain Architecture
Description	Carboxypeptidase-like protein X2 precursor.

CNTP2_HUMAN
θ value	2.60593e-15 (rank : 20)	NC score	0.450304 (rank : 41)
Query Neighborhood Hits	118	Target Neighborhood Hits	199	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UHC6, Q52LV1, Q5H9Q7, Q9UQ12	Gene names	CNTNAP2, CASPR2, KIAA0868
Domain Architecture
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

CUBN_HUMAN
θ value	2.20605e-14 (rank : 21)	NC score	0.415413 (rank : 54)
Query Neighborhood Hits	118	Target Neighborhood Hits	482	Shared Neighborhood Hits	77
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

TSG6_HUMAN
θ value	2.20605e-14 (rank : 22)	NC score	0.557852 (rank : 21)
Query Neighborhood Hits	118	Target Neighborhood Hits	91	Shared Neighborhood Hits	62
SwissProt Accessions	P98066, Q8WWI9	Gene names	TNFAIP6, TSG6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein) (Hyaluronate-binding protein).

BMP1_MOUSE
θ value	3.76295e-14 (rank : 23)	NC score	0.546436 (rank : 25)
Query Neighborhood Hits	118	Target Neighborhood Hits	236	Shared Neighborhood Hits	64
SwissProt Accessions	P98063	Gene names	Bmp1
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

MFRP_MOUSE
θ value	3.76295e-14 (rank : 24)	NC score	0.550284 (rank : 23)
Query Neighborhood Hits	118	Target Neighborhood Hits	166	Shared Neighborhood Hits	67
SwissProt Accessions	Q8K480, Q8BPP4	Gene names	Mfrp
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

CNTP2_MOUSE
θ value	6.41864e-14 (rank : 25)	NC score	0.439102 (rank : 47)
Query Neighborhood Hits	118	Target Neighborhood Hits	194	Shared Neighborhood Hits	33
SwissProt Accessions	Q9CPW0, Q6P2K4, Q6ZQ31	Gene names	Cntnap2, Kiaa0868
Domain Architecture	No domain graphic available
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

CUBN_MOUSE
θ value	6.41864e-14 (rank : 26)	NC score	0.413380 (rank : 56)
Query Neighborhood Hits	118	Target Neighborhood Hits	477	Shared Neighborhood Hits	78
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

GP126_HUMAN
θ value	6.41864e-14 (rank : 27)	NC score	0.368947 (rank : 63)
Query Neighborhood Hits	118	Target Neighborhood Hits	187	Shared Neighborhood Hits	63
SwissProt Accessions	Q86SQ4, Q6MZU7, Q8NC14, Q96JW0	Gene names	GPR126
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 126 precursor.

TSG6_MOUSE
θ value	6.41864e-14 (rank : 28)	NC score	0.555235 (rank : 22)
Query Neighborhood Hits	118	Target Neighborhood Hits	91	Shared Neighborhood Hits	62
SwissProt Accessions	O08859	Gene names	Tnfaip6, Tnfip6, Tsg6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein).

CNTP4_MOUSE
θ value	8.38298e-14 (rank : 29)	NC score	0.435642 (rank : 50)
Query Neighborhood Hits	118	Target Neighborhood Hits	193	Shared Neighborhood Hits	37
SwissProt Accessions	Q99P47	Gene names	Cntnap4, Caspr4
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

PCOC1_MOUSE
θ value	1.42992e-13 (rank : 30)	NC score	0.636314 (rank : 14)
Query Neighborhood Hits	118	Target Neighborhood Hits	100	Shared Neighborhood Hits	65
SwissProt Accessions	Q61398, O35113	Gene names	Pcolce, Pcpe1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein) (P14).

CNTP4_HUMAN
θ value	1.86753e-13 (rank : 31)	NC score	0.432573 (rank : 52)
Query Neighborhood Hits	118	Target Neighborhood Hits	187	Shared Neighborhood Hits	35
SwissProt Accessions	Q9C0A0	Gene names	CNTNAP4, CASPR4, KIAA1763
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

BMP1_HUMAN
θ value	2.43908e-13 (rank : 32)	NC score	0.546135 (rank : 26)
Query Neighborhood Hits	118	Target Neighborhood Hits	233	Shared Neighborhood Hits	64
SwissProt Accessions	P13497, Q13292, Q13872, Q14874, Q99421, Q99422, Q99423, Q9UL38	Gene names	BMP1, PCOLC
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

CPXM1_HUMAN
θ value	4.16044e-13 (rank : 33)	NC score	0.410855 (rank : 57)
Query Neighborhood Hits	118	Target Neighborhood Hits	69	Shared Neighborhood Hits	32
SwissProt Accessions	Q96SM3, Q6P4G8, Q6UW65, Q9NUB5	Gene names	CPXM1, CPX1, CPXM
Domain Architecture
Description	Probable carboxypeptidase X1 precursor (EC 3.4.17.-) (Metallocarboxypeptidase CPX-1).

TLL2_MOUSE
θ value	4.16044e-13 (rank : 34)	NC score	0.545741 (rank : 27)
Query Neighborhood Hits	118	Target Neighborhood Hits	240	Shared Neighborhood Hits	66
SwissProt Accessions	Q9WVM6	Gene names	Tll2
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

DMBT1_HUMAN
θ value	5.43371e-13 (rank : 35)	NC score	0.404183 (rank : 58)
Query Neighborhood Hits	118	Target Neighborhood Hits	152	Shared Neighborhood Hits	64
SwissProt Accessions	Q9UGM3, Q59EX0, Q5JR26, Q6MZN4, Q96DU4, Q9UGM2, Q9UJ57, Q9UKJ4, Q9Y211, Q9Y4V9	Gene names	DMBT1, GP340
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (Glycoprotein 340) (Gp-340) (Surfactant pulmonary-associated D-binding protein).

CUZD1_HUMAN
θ value	7.09661e-13 (rank : 36)	NC score	0.561816 (rank : 20)
Query Neighborhood Hits	118	Target Neighborhood Hits	89	Shared Neighborhood Hits	61
SwissProt Accessions	Q86UP6, Q7Z660, Q7Z661, Q86SG1, Q86UP5, Q9HAR7	Gene names	CUZD1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Transmembrane protein UO-44).

PCOC1_HUMAN
θ value	9.26847e-13 (rank : 37)	NC score	0.631004 (rank : 15)
Query Neighborhood Hits	118	Target Neighborhood Hits	146	Shared Neighborhood Hits	64
SwissProt Accessions	Q15113, O14550	Gene names	PCOLCE, PCPE1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein).

TLL2_HUMAN
θ value	9.26847e-13 (rank : 38)	NC score	0.545686 (rank : 28)
Query Neighborhood Hits	118	Target Neighborhood Hits	241	Shared Neighborhood Hits	66
SwissProt Accessions	Q9Y6L7, Q6PJN5, Q9UQ00	Gene names	TLL2, KIAA0932
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

PCOC2_MOUSE
θ value	1.2105e-12 (rank : 39)	NC score	0.640793 (rank : 12)
Query Neighborhood Hits	118	Target Neighborhood Hits	73	Shared Neighborhood Hits	63
SwissProt Accessions	Q8R4W6, Q3V1K6, Q9CX06	Gene names	Pcolce2, Pcpe2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

TLL1_HUMAN
θ value	1.2105e-12 (rank : 40)	NC score	0.544429 (rank : 31)
Query Neighborhood Hits	118	Target Neighborhood Hits	236	Shared Neighborhood Hits	66
SwissProt Accessions	O43897, Q96AN3, Q9NQS4	Gene names	TLL1, TLL
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-).

CNTP3_HUMAN
θ value	2.0648e-12 (rank : 41)	NC score	0.438902 (rank : 48)
Query Neighborhood Hits	118	Target Neighborhood Hits	195	Shared Neighborhood Hits	35
SwissProt Accessions	Q9BZ76, Q9C0E9	Gene names	CNTNAP3, CASPR3, KIAA1714
Domain Architecture
Description	Contactin-associated protein-like 3 precursor (Cell recognition molecule Caspr3).

TLL1_MOUSE
θ value	6.00763e-12 (rank : 42)	NC score	0.542372 (rank : 32)
Query Neighborhood Hits	118	Target Neighborhood Hits	237	Shared Neighborhood Hits	64
SwissProt Accessions	Q62381, Q3UTT9, Q8BNP5	Gene names	Tll1, Tll
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-) (mTll).

CUZD1_MOUSE
θ value	7.84624e-12 (rank : 43)	NC score	0.549274 (rank : 24)
Query Neighborhood Hits	118	Target Neighborhood Hits	91	Shared Neighborhood Hits	60
SwissProt Accessions	P70412, Q9CTZ7	Gene names	Cuzd1, Itmap1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Integral membrane-associated protein 1).

PCOC2_HUMAN
θ value	1.33837e-11 (rank : 44)	NC score	0.637634 (rank : 13)
Query Neighborhood Hits	118	Target Neighborhood Hits	73	Shared Neighborhood Hits	62
SwissProt Accessions	Q9UKZ9, Q9BRH3	Gene names	PCOLCE2, PCPE2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

DDR2_MOUSE
θ value	1.74796e-11 (rank : 45)	NC score	0.150645 (rank : 89)
Query Neighborhood Hits	118	Target Neighborhood Hits	813	Shared Neighborhood Hits	32
SwissProt Accessions	Q62371	Gene names	Ddr2, Ntrkr3, Tkt, Tyro10
Domain Architecture
Description	Discoidin domain-containing receptor 2 precursor (EC 2.7.10.1) (Discoidin domain receptor 2) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO 10) (Neurotrophic tyrosine kinase, receptor-related 3) (CD167b antigen).

MFRP_HUMAN
θ value	1.74796e-11 (rank : 46)	NC score	0.537753 (rank : 33)
Query Neighborhood Hits	118	Target Neighborhood Hits	165	Shared Neighborhood Hits	66
SwissProt Accessions	Q9BY79, Q335M3, Q96DQ9	Gene names	MFRP
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

DDR2_HUMAN
θ value	2.28291e-11 (rank : 47)	NC score	0.149578 (rank : 90)
Query Neighborhood Hits	118	Target Neighborhood Hits	818	Shared Neighborhood Hits	32
SwissProt Accessions	Q16832	Gene names	DDR2, NTRKR3, TKT, TYRO10
Domain Architecture
Description	Discoidin domain-containing receptor 2 precursor (EC 2.7.10.1) (Discoidin domain receptor 2) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO 10) (Neurotrophic tyrosine kinase, receptor-related 3) (CD167b antigen).

DMBT1_MOUSE
θ value	2.98157e-11 (rank : 48)	NC score	0.451912 (rank : 39)
Query Neighborhood Hits	118	Target Neighborhood Hits	134	Shared Neighborhood Hits	65
SwissProt Accessions	Q60997, Q80YC6, Q9JMJ9	Gene names	Dmbt1, Crpd
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (CRP-ductin) (Vomeroglandin).

CSMD2_HUMAN
θ value	1.47974e-10 (rank : 49)	NC score	0.446535 (rank : 42)
Query Neighborhood Hits	118	Target Neighborhood Hits	188	Shared Neighborhood Hits	68
SwissProt Accessions	Q7Z408, Q5VT59, Q8N963, Q96Q03, Q9H4V7, Q9H4V8, Q9H4V9, Q9H4W0, Q9H4W1, Q9H4W2, Q9H4W3, Q9H4W4, Q9HCY5, Q9HCY6, Q9HCY7	Gene names	CSMD2, KIAA1884
Domain Architecture
Description	CUB and sushi domain-containing protein 2 (CUB and sushi multiple domains protein 2).

CPXM1_MOUSE
θ value	2.52405e-10 (rank : 50)	NC score	0.399664 (rank : 61)
Query Neighborhood Hits	118	Target Neighborhood Hits	63	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Z100, Q99LA3	Gene names	Cpxm1, Cpx1, Cpxm
Domain Architecture
Description	Probable carboxypeptidase X1 precursor (EC 3.4.17.-) (Metallocarboxypeptidase CPX-1).

CSMD1_HUMAN
θ value	3.29651e-10 (rank : 51)	NC score	0.434665 (rank : 51)
Query Neighborhood Hits	118	Target Neighborhood Hits	176	Shared Neighborhood Hits	65
SwissProt Accessions	Q96PZ7, Q96QU9, Q96RM4	Gene names	CSMD1, KIAA1890
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

CSMD1_MOUSE
θ value	9.59137e-10 (rank : 52)	NC score	0.436146 (rank : 49)
Query Neighborhood Hits	118	Target Neighborhood Hits	193	Shared Neighborhood Hits	66
SwissProt Accessions	Q923L3, Q8BUV1, Q8BYQ3	Gene names	Csmd1
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

C1RA_MOUSE
θ value	1.63604e-09 (rank : 53)	NC score	0.326540 (rank : 65)
Query Neighborhood Hits	118	Target Neighborhood Hits	379	Shared Neighborhood Hits	61
SwissProt Accessions	Q8CG16, Q99KI6, Q9ET60	Gene names	C1ra, C1r
Domain Architecture
Description	Complement C1r-A subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-A subcomponent) [Contains: Complement C1r-A subcomponent heavy chain; Complement C1r-A subcomponent light chain].

C1S_HUMAN
θ value	1.63604e-09 (rank : 54)	NC score	0.325592 (rank : 66)
Query Neighborhood Hits	118	Target Neighborhood Hits	359	Shared Neighborhood Hits	62
SwissProt Accessions	P09871, Q9UCU7, Q9UCU8, Q9UCU9, Q9UCV0, Q9UCV1, Q9UCV2, Q9UCV3, Q9UCV4, Q9UCV5, Q9UM14	Gene names	C1S
Domain Architecture
Description	Complement C1s subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s subcomponent heavy chain; Complement C1s subcomponent light chain].

C1RB_MOUSE
θ value	2.79066e-09 (rank : 55)	NC score	0.322226 (rank : 68)
Query Neighborhood Hits	118	Target Neighborhood Hits	380	Shared Neighborhood Hits	61
SwissProt Accessions	Q8CFG9	Gene names	C1rb, C1r
Domain Architecture	No domain graphic available
Description	Complement C1r-B subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-B subcomponent) [Contains: Complement C1r-B subcomponent heavy chain; Complement C1r-B subcomponent light chain].

CS1B_MOUSE
θ value	2.79066e-09 (rank : 56)	NC score	0.320811 (rank : 69)
Query Neighborhood Hits	118	Target Neighborhood Hits	361	Shared Neighborhood Hits	63
SwissProt Accessions	Q8CFG8	Gene names	C1sb, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-B subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-B subcomponent heavy chain; Complement C1s-B subcomponent light chain].

C1R_HUMAN
θ value	6.21693e-09 (rank : 57)	NC score	0.327821 (rank : 64)
Query Neighborhood Hits	118	Target Neighborhood Hits	364	Shared Neighborhood Hits	60
SwissProt Accessions	P00736, Q8J012	Gene names	C1R
Domain Architecture
Description	Complement C1r subcomponent precursor (EC 3.4.21.41) (Complement component 1, r subcomponent) [Contains: Complement C1r subcomponent heavy chain; Complement C1r subcomponent light chain].

CS1A_MOUSE
θ value	6.21693e-09 (rank : 58)	NC score	0.323637 (rank : 67)
Query Neighborhood Hits	118	Target Neighborhood Hits	360	Shared Neighborhood Hits	63
SwissProt Accessions	Q8CG14, Q8BJC4, Q8CH28, Q8VBY4	Gene names	C1sa, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-A subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-A subcomponent heavy chain; Complement C1s-A subcomponent light chain].

CNTP1_HUMAN
θ value	1.38499e-08 (rank : 59)	NC score	0.403071 (rank : 59)
Query Neighborhood Hits	118	Target Neighborhood Hits	196	Shared Neighborhood Hits	33
SwissProt Accessions	P78357	Gene names	CNTNAP1, CASPR, NRXN4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (p190).

DDR1_HUMAN
θ value	3.08544e-08 (rank : 60)	NC score	0.135966 (rank : 95)
Query Neighborhood Hits	118	Target Neighborhood Hits	819	Shared Neighborhood Hits	32
SwissProt Accessions	Q08345, Q14196, Q16562, Q5ST12, Q9UD37	Gene names	DDR1, CAK, EDDR1, RTK6, TRKE
Domain Architecture
Description	Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (TRK E) (Protein-tyrosine kinase RTK 6) (HGK2) (CD167a antigen).

NETO2_MOUSE
θ value	4.0297e-08 (rank : 61)	NC score	0.544873 (rank : 30)
Query Neighborhood Hits	118	Target Neighborhood Hits	113	Shared Neighborhood Hits	63
SwissProt Accessions	Q8BNJ6, Q5VM49, Q8C4Q8	Gene names	Neto2, Btcl2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

CNTP1_MOUSE
θ value	5.26297e-08 (rank : 62)	NC score	0.402303 (rank : 60)
Query Neighborhood Hits	118	Target Neighborhood Hits	183	Shared Neighborhood Hits	33
SwissProt Accessions	O54991	Gene names	Cntnap1, Nrxn4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (Paranodin) (NCP1) (MHDNIV).

LRP12_HUMAN
θ value	5.26297e-08 (rank : 63)	NC score	0.439711 (rank : 46)
Query Neighborhood Hits	118	Target Neighborhood Hits	205	Shared Neighborhood Hits	66
SwissProt Accessions	Q9Y561	Gene names	LRP12, ST7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor (Suppressor of tumorigenicity protein 7).

MASP2_HUMAN
θ value	6.87365e-08 (rank : 64)	NC score	0.316223 (rank : 70)
Query Neighborhood Hits	118	Target Neighborhood Hits	364	Shared Neighborhood Hits	62
SwissProt Accessions	O00187, O75754, Q5TEQ5, Q5TER0, Q96QG4, Q9BZH0, Q9H498, Q9H499, Q9UBP3, Q9ULC7, Q9UMV3, Q9Y270	Gene names	MASP2
Domain Architecture
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

NETO2_HUMAN
θ value	6.87365e-08 (rank : 65)	NC score	0.545591 (rank : 29)
Query Neighborhood Hits	118	Target Neighborhood Hits	109	Shared Neighborhood Hits	64
SwissProt Accessions	Q8NC67, Q7Z381, Q8ND51, Q96SP4, Q9NVY8	Gene names	NETO2, BTCL2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

CSMD3_HUMAN
θ value	8.97725e-08 (rank : 66)	NC score	0.431555 (rank : 53)
Query Neighborhood Hits	118	Target Neighborhood Hits	199	Shared Neighborhood Hits	65
SwissProt Accessions	Q7Z407, Q96PZ3	Gene names	CSMD3, KIAA1894
Domain Architecture
Description	CUB and sushi domain-containing protein 3 precursor (CUB and sushi multiple domains protein 3).

MASP1_MOUSE
θ value	8.97725e-08 (rank : 67)	NC score	0.308358 (rank : 72)
Query Neighborhood Hits	118	Target Neighborhood Hits	364	Shared Neighborhood Hits	63
SwissProt Accessions	P98064	Gene names	Masp1, Crarf
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) [Contains: Complement- activating component of Ra-reactive factor heavy chain; Complement- activating component of Ra-reactive factor light chain].

DDR1_MOUSE
θ value	2.61198e-07 (rank : 68)	NC score	0.129487 (rank : 99)
Query Neighborhood Hits	118	Target Neighborhood Hits	818	Shared Neighborhood Hits	32
SwissProt Accessions	Q03146	Gene names	Ddr1, Cak, Eddr1, Mpk6
Domain Architecture
Description	Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (Protein-tyrosine kinase MPK-6) (CD167a antigen).

MASP1_HUMAN
θ value	2.61198e-07 (rank : 69)	NC score	0.312467 (rank : 71)
Query Neighborhood Hits	118	Target Neighborhood Hits	369	Shared Neighborhood Hits	64
SwissProt Accessions	P48740, O95570, Q9UF09	Gene names	MASP1, CRARF, CRARF1, PRSS5
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) (Mannose-binding protein- associated serine protease) (MASP-1) [Contains: Complement-activating component of Ra-reactive factor heavy chain; Complement-activating component of Ra-reactive factor light chain].

LRP12_MOUSE
θ value	3.41135e-07 (rank : 70)	NC score	0.443031 (rank : 44)
Query Neighborhood Hits	118	Target Neighborhood Hits	180	Shared Neighborhood Hits	66
SwissProt Accessions	Q8BUJ9, Q8BWM9	Gene names	Lrp12
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor.

NETO1_MOUSE
θ value	1.29631e-06 (rank : 71)	NC score	0.535043 (rank : 34)
Query Neighborhood Hits	118	Target Neighborhood Hits	109	Shared Neighborhood Hits	64
SwissProt Accessions	Q8R4I7, Q80X39, Q8C4S3, Q8CCM2	Gene names	Neto1, Btcl1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

ST14_HUMAN
θ value	1.29631e-06 (rank : 72)	NC score	0.240319 (rank : 78)
Query Neighborhood Hits	118	Target Neighborhood Hits	409	Shared Neighborhood Hits	65
SwissProt Accessions	Q9Y5Y6, Q9BS01, Q9H3S0, Q9HB36, Q9HCA3	Gene names	ST14, PRSS14, SNC19, TADG15
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Matriptase) (Membrane-type serine protease 1) (MT-SP1) (Prostamin) (Serine protease TADG-15) (Tumor-associated differentially-expressed gene 15 protein).

ST14_MOUSE
θ value	1.29631e-06 (rank : 73)	NC score	0.241798 (rank : 77)
Query Neighborhood Hits	118	Target Neighborhood Hits	419	Shared Neighborhood Hits	65
SwissProt Accessions	P56677	Gene names	St14, Prss14
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Epithin).

VITRN_HUMAN
θ value	1.69304e-06 (rank : 74)	NC score	0.138701 (rank : 93)
Query Neighborhood Hits	118	Target Neighborhood Hits	63	Shared Neighborhood Hits	11
SwissProt Accessions	Q6UXI7, Q6P7T3, Q96DT1	Gene names	VIT
Domain Architecture	No domain graphic available
Description	Vitrin precursor.

NETO1_HUMAN
θ value	2.21117e-06 (rank : 75)	NC score	0.532750 (rank : 35)
Query Neighborhood Hits	118	Target Neighborhood Hits	110	Shared Neighborhood Hits	65
SwissProt Accessions	Q8TDF5, Q86W85, Q8ND78, Q8TDF4	Gene names	NETO1, BTCL1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

VITRN_MOUSE
θ value	3.77169e-06 (rank : 76)	NC score	0.134920 (rank : 96)
Query Neighborhood Hits	118	Target Neighborhood Hits	68	Shared Neighborhood Hits	11
SwissProt Accessions	Q8VHI5, Q3TZ47, Q8BQ41, Q8K047, Q9CYZ1	Gene names	Vit
Domain Architecture	No domain graphic available
Description	Vitrin precursor.

ENTK_MOUSE
θ value	1.09739e-05 (rank : 77)	NC score	0.221787 (rank : 80)
Query Neighborhood Hits	118	Target Neighborhood Hits	338	Shared Neighborhood Hits	68
SwissProt Accessions	P97435	Gene names	Prss7, Entk
Domain Architecture
Description	Enteropeptidase (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

LRP3_HUMAN
θ value	1.87187e-05 (rank : 78)	NC score	0.370852 (rank : 62)
Query Neighborhood Hits	118	Target Neighborhood Hits	280	Shared Neighborhood Hits	66
SwissProt Accessions	O75074	Gene names	LRP3
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 3 precursor (hLRp105).

ENTK_HUMAN
θ value	3.19293e-05 (rank : 79)	NC score	0.201650 (rank : 83)
Query Neighborhood Hits	118	Target Neighborhood Hits	310	Shared Neighborhood Hits	67
SwissProt Accessions	P98073	Gene names	PRSS7, ENTK
Domain Architecture
Description	Enteropeptidase precursor (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

MASP2_MOUSE
θ value	3.19293e-05 (rank : 80)	NC score	0.306785 (rank : 73)
Query Neighborhood Hits	118	Target Neighborhood Hits	382	Shared Neighborhood Hits	61
SwissProt Accessions	Q91WP0, Q9QXA4, Q9QXD2, Q9QXD5, Q9Z338	Gene names	Masp2
Domain Architecture	No domain graphic available
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

CRLD2_HUMAN
θ value	0.000121331 (rank : 81)	NC score	0.163343 (rank : 85)
Query Neighborhood Hits	118	Target Neighborhood Hits	29	Shared Neighborhood Hits	11
SwissProt Accessions	Q9H0B8, Q6P590, Q6UWH0, Q6UXC6, Q96IB1, Q96K61	Gene names	CRISPLD2, CRISP11, LCRISP2
Domain Architecture	No domain graphic available
Description	Cysteine-rich secretory protein LCCL domain-containing 2 precursor (LCCL domain-containing cysteine-rich secretory protein 2) (Cysteine- rich secretory protein 11) (CRISP-11).

COCH_HUMAN
θ value	0.00020696 (rank : 82)	NC score	0.131007 (rank : 97)
Query Neighborhood Hits	118	Target Neighborhood Hits	51	Shared Neighborhood Hits	11
SwissProt Accessions	O43405	Gene names	COCH, COCH5B2
Domain Architecture
Description	Cochlin precursor (COCH-5B2).

PDGFD_HUMAN
θ value	0.000461057 (rank : 83)	NC score	0.480754 (rank : 38)
Query Neighborhood Hits	118	Target Neighborhood Hits	74	Shared Neighborhood Hits	58
SwissProt Accessions	Q9GZP0, Q9BWV5	Gene names	PDGFD, IEGF, SCDGFB
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor D precursor (PDGF D) (Iris-expressed growth factor) (Spinal cord-derived growth factor B) (SCDGF-B).

SEZ6L_HUMAN
θ value	0.000786445 (rank : 84)	NC score	0.415000 (rank : 55)
Query Neighborhood Hits	118	Target Neighborhood Hits	289	Shared Neighborhood Hits	65
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.

CRLD1_HUMAN
θ value	0.00102713 (rank : 85)	NC score	0.141592 (rank : 92)
Query Neighborhood Hits	118	Target Neighborhood Hits	25	Shared Neighborhood Hits	11
SwissProt Accessions	Q9H336	Gene names	CRISPLD1, CRISP10, LCRISP1
Domain Architecture	No domain graphic available
Description	Cysteine-rich secretory protein LCCL domain-containing 1 precursor (LCCL domain-containing cysteine-rich secretory protein 1) (Cysteine- rich secretory protein 10) (CRISP-10) (Trypsin inhibitor Hl) (CocoaCrisp).

CRLD1_MOUSE
θ value	0.00102713 (rank : 86)	NC score	0.143036 (rank : 91)
Query Neighborhood Hits	118	Target Neighborhood Hits	23	Shared Neighborhood Hits	11
SwissProt Accessions	Q8CGD2, Q8K018, Q99MM6	Gene names	Crispld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich secretory protein LCCL domain-containing 1 precursor (CocoaCrisp).

COCH_MOUSE
θ value	0.00175202 (rank : 87)	NC score	0.122253 (rank : 101)
Query Neighborhood Hits	118	Target Neighborhood Hits	51	Shared Neighborhood Hits	11
SwissProt Accessions	Q62507, Q3TAF5, Q9QWK6	Gene names	Coch
Domain Architecture
Description	Cochlin precursor (COCH-5B2).

KREM1_MOUSE
θ value	0.0252991 (rank : 88)	NC score	0.286246 (rank : 75)
Query Neighborhood Hits	118	Target Neighborhood Hits	92	Shared Neighborhood Hits	57
SwissProt Accessions	Q99N43	Gene names	Kremen1, Kremen
Domain Architecture
Description	Kremen protein 1 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 1) (Dickkopf receptor).

SSPO_MOUSE
θ value	0.0252991 (rank : 89)	NC score	0.082000 (rank : 147)
Query Neighborhood Hits	118	Target Neighborhood Hits	800	Shared Neighborhood Hits	38
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

KREM1_HUMAN
θ value	0.0563607 (rank : 90)	NC score	0.293626 (rank : 74)
Query Neighborhood Hits	118	Target Neighborhood Hits	90	Shared Neighborhood Hits	59
SwissProt Accessions	Q96MU8, Q5TIB9, Q6P3X6, Q9BY70, Q9UGS5, Q9UGU1	Gene names	KREMEN1, KREMEN, KRM1
Domain Architecture
Description	Kremen protein 1 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 1) (Dickkopf receptor).

LRP10_MOUSE
θ value	0.125558 (rank : 91)	NC score	0.179992 (rank : 84)
Query Neighborhood Hits	118	Target Neighborhood Hits	169	Shared Neighborhood Hits	38
SwissProt Accessions	Q7TQH7, Q7TS95, Q921T0, Q9EPE8	Gene names	Lrp10, Lrp9
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

PHF22_HUMAN
θ value	0.125558 (rank : 92)	NC score	0.031842 (rank : 382)
Query Neighborhood Hits	118	Target Neighborhood Hits	121	Shared Neighborhood Hits	3
SwissProt Accessions	Q96CB8, Q9HD71	Gene names	INTS12, PHF22
Domain Architecture	No domain graphic available
Description	Integrator complex subunit 12 (PHD finger protein 22).

MYCB2_HUMAN
θ value	0.365318 (rank : 93)	NC score	0.015520 (rank : 389)
Query Neighborhood Hits	118	Target Neighborhood Hits	390	Shared Neighborhood Hits	2
SwissProt Accessions	O75592, Q5JSX8, Q5VZN6, Q6PIB6, Q9UQ11, Q9Y6E4	Gene names	MYCBP2, KIAA0916, PAM
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

SYNPO_MOUSE
θ value	0.62314 (rank : 94)	NC score	0.017844 (rank : 386)
Query Neighborhood Hits	118	Target Neighborhood Hits	242	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CC35, Q99JI0	Gene names	Synpo, Kiaa1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

CDCP1_HUMAN
θ value	0.813845 (rank : 95)	NC score	0.074156 (rank : 180)
Query Neighborhood Hits	118	Target Neighborhood Hits	33	Shared Neighborhood Hits	20
SwissProt Accessions	Q9H5V8, Q49UB4, Q6NT71, Q6U9Y2, Q8WU91, Q96QU7, Q9H676, Q9H8C2	Gene names	CDCP1, TRASK
Domain Architecture	No domain graphic available
Description	CUB domain-containing protein 1 precursor (Transmembrane and associated with src kinases) (Membrane glycoprotein gp140) (Subtractive immunization M plus HEp3-associated 135 kDa protein) (SIMA135) (CD318 antigen).

ATRN_HUMAN
θ value	1.06291 (rank : 96)	NC score	0.205577 (rank : 81)
Query Neighborhood Hits	118	Target Neighborhood Hits	525	Shared Neighborhood Hits	57
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

ATRN_MOUSE
θ value	1.06291 (rank : 97)	NC score	0.202718 (rank : 82)
Query Neighborhood Hits	118	Target Neighborhood Hits	519	Shared Neighborhood Hits	59
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

LRP10_HUMAN
θ value	1.06291 (rank : 98)	NC score	0.153550 (rank : 88)
Query Neighborhood Hits	118	Target Neighborhood Hits	197	Shared Neighborhood Hits	35
SwissProt Accessions	Q7Z4F1, O95882, Q86T02, Q8NCZ4, Q9HC42, Q9UG33	Gene names	LRP10
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

SCUB3_MOUSE
θ value	1.06291 (rank : 99)	NC score	0.157818 (rank : 86)
Query Neighborhood Hits	118	Target Neighborhood Hits	442	Shared Neighborhood Hits	65
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

MOGT2_MOUSE
θ value	1.38821 (rank : 100)	NC score	0.010059 (rank : 390)
Query Neighborhood Hits	118	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q80W94	Gene names	Mogat2, Dgat2l5, Mgat1l
Domain Architecture	No domain graphic available
Description	2-acylglycerol O-acyltransferase 2 (EC 2.3.1.22) (Monoacylglycerol O- acyltransferase 2) (Acyl CoA:monoacylglycerol acyltransferase 2) (MGAT2) (Diacylglycerol acyltransferase 2-like protein 5) (Monoacylglycerol O-acyltransferase 1-like).

SCUB3_HUMAN
θ value	1.38821 (rank : 101)	NC score	0.156121 (rank : 87)
Query Neighborhood Hits	118	Target Neighborhood Hits	428	Shared Neighborhood Hits	65
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SDC4_HUMAN
θ value	1.38821 (rank : 102)	NC score	0.027841 (rank : 383)
Query Neighborhood Hits	118	Target Neighborhood Hits	22	Shared Neighborhood Hits	4
SwissProt Accessions	P31431, O00773, Q16833	Gene names	SDC4
Domain Architecture
Description	Syndecan-4 precursor (SYND4) (Amphiglycan) (Ryudocan core protein).

AP180_HUMAN
θ value	1.81305 (rank : 103)	NC score	0.019789 (rank : 384)
Query Neighborhood Hits	118	Target Neighborhood Hits	183	Shared Neighborhood Hits	5
SwissProt Accessions	O60641, Q5JX13, Q68DL9, Q6P9D3, Q9NTY7	Gene names	SNAP91, KIAA0656
Domain Architecture
Description	Clathrin coat assembly protein AP180 (Clathrin coat-associated protein AP180) (91 kDa synaptosomal-associated protein).

CDCP1_MOUSE
θ value	1.81305 (rank : 104)	NC score	0.061321 (rank : 244)
Query Neighborhood Hits	118	Target Neighborhood Hits	32	Shared Neighborhood Hits	17
SwissProt Accessions	Q5U462, Q810J0, Q921M9	Gene names	Cdcp1
Domain Architecture	No domain graphic available
Description	CUB domain-containing protein 1 precursor (Transmembrane and associated with src kinases) (Membrane glycoprotein gp140) (CD318 antigen).

FMN2_HUMAN
θ value	1.81305 (rank : 105)	NC score	0.006436 (rank : 393)
Query Neighborhood Hits	118	Target Neighborhood Hits	484	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

AP180_MOUSE
θ value	2.36792 (rank : 106)	NC score	0.018215 (rank : 385)
Query Neighborhood Hits	118	Target Neighborhood Hits	194	Shared Neighborhood Hits	6
SwissProt Accessions	Q61548, Q61547	Gene names	Snap91
Domain Architecture
Description	Clathrin coat assembly protein AP180 (Clathrin coat-associated protein AP180) (91 kDa synaptosomal-associated protein) (Phosphoprotein F1- 20).

EGR1_HUMAN
θ value	3.0926 (rank : 107)	NC score	-0.005175 (rank : 401)
Query Neighborhood Hits	118	Target Neighborhood Hits	788	Shared Neighborhood Hits	4
SwissProt Accessions	P18146	Gene names	EGR1, ZNF225
Domain Architecture
Description	Early growth response protein 1 (EGR-1) (Krox-24 protein) (Transcription factor Zif268) (Nerve growth factor-induced protein A) (NGFI-A) (Transcription factor ETR103) (Zinc finger protein 225) (AT225).

OXRP_HUMAN
θ value	3.0926 (rank : 108)	NC score	0.003613 (rank : 397)
Query Neighborhood Hits	118	Target Neighborhood Hits	544	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y4L1	Gene names	HYOU1, ORP150
Domain Architecture
Description	150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia up- regulated 1).

SP4_MOUSE
θ value	3.0926 (rank : 109)	NC score	-0.004268 (rank : 399)
Query Neighborhood Hits	118	Target Neighborhood Hits	759	Shared Neighborhood Hits	5
SwissProt Accessions	Q62445	Gene names	Sp4
Domain Architecture
Description	Transcription factor Sp4.

IPO4_HUMAN
θ value	4.03905 (rank : 110)	NC score	0.017045 (rank : 388)
Query Neighborhood Hits	118	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TEX9, Q86TZ9, Q8NCG8, Q96SJ3, Q9BTI4, Q9H5L0	Gene names	IPO4, IMP4B, RANBP4
Domain Architecture
Description	Importin-4 (Importin 4b) (Imp4b) (Ran-binding protein 4) (RanBP4).

TITIN_HUMAN
θ value	5.27518 (rank : 111)	NC score	-0.002358 (rank : 398)
Query Neighborhood Hits	118	Target Neighborhood Hits	2923	Shared Neighborhood Hits	13
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

CJ047_MOUSE
θ value	6.88961 (rank : 112)	NC score	0.009415 (rank : 391)
Query Neighborhood Hits	118	Target Neighborhood Hits	76	Shared Neighborhood Hits	2
SwissProt Accessions	Q8C5R2, Q8R017, Q8R2Z9	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf47 homolog.

DICER_MOUSE
θ value	6.88961 (rank : 113)	NC score	0.004803 (rank : 395)
Query Neighborhood Hits	118	Target Neighborhood Hits	140	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R418	Gene names	Dicer1, Dicer, Mdcr
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Double-strand-specific ribonuclease mDCR-1).

PLS1_HUMAN
θ value	6.88961 (rank : 114)	NC score	0.005418 (rank : 394)
Query Neighborhood Hits	118	Target Neighborhood Hits	35	Shared Neighborhood Hits	3
SwissProt Accessions	O15162	Gene names	PLSCR1
Domain Architecture
Description	Phospholipid scramblase 1 (PL scramblase 1) (Ca(2+)-dependent phospholipid scramblase 1) (Erythrocyte phospholipid scramblase) (MmTRA1b).

SDC3_MOUSE
θ value	6.88961 (rank : 115)	NC score	0.017592 (rank : 387)
Query Neighborhood Hits	118	Target Neighborhood Hits	107	Shared Neighborhood Hits	6
SwissProt Accessions	Q64519, Q3UDD9, Q6ZQA4, Q7TQD4	Gene names	Sdc3, Kiaa0468
Domain Architecture
Description	Syndecan-3 precursor (SYND3).

SP4_HUMAN
θ value	6.88961 (rank : 116)	NC score	-0.004737 (rank : 400)
Query Neighborhood Hits	118	Target Neighborhood Hits	749	Shared Neighborhood Hits	5
SwissProt Accessions	Q02446, O60402	Gene names	SP4
Domain Architecture
Description	Transcription factor Sp4 (SPR-1).

EMSY_HUMAN
θ value	8.99809 (rank : 117)	NC score	0.004346 (rank : 396)
Query Neighborhood Hits	118	Target Neighborhood Hits	296	Shared Neighborhood Hits	7
SwissProt Accessions	Q7Z589, Q4G109, Q8NBU6, Q8TE50, Q9H8I9, Q9NRH0	Gene names	EMSY, C11orf30
Domain Architecture
Description	Protein EMSY.

TIP_HUMAN
θ value	8.99809 (rank : 118)	NC score	0.007189 (rank : 392)
Query Neighborhood Hits	118	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TB96, Q96SR4, Q9BRE2, Q9H2V9	Gene names	ITFG1, TIP
Domain Architecture	No domain graphic available
Description	T-cell immunomodulatory protein precursor (Protein TIP) (Integrin alpha FG-GAP repeat-containing protein 1).

ACRO_HUMAN
θ value	θ > 10 (rank : 119)	NC score	0.059372 (rank : 266)
Query Neighborhood Hits	118	Target Neighborhood Hits	291	Shared Neighborhood Hits	16
SwissProt Accessions	P10323, Q6ICK2	Gene names	ACR, ACRS
Domain Architecture
Description	Acrosin precursor (EC 3.4.21.10) [Contains: Acrosin light chain; Acrosin heavy chain].

ACRO_MOUSE
θ value	θ > 10 (rank : 120)	NC score	0.060177 (rank : 253)
Query Neighborhood Hits	118	Target Neighborhood Hits	185	Shared Neighborhood Hits	14
SwissProt Accessions	P23578	Gene names	Acr
Domain Architecture
Description	Acrosin precursor (EC 3.4.21.10) [Contains: Acrosin light chain; Acrosin heavy chain].

AGRIN_HUMAN
θ value	θ > 10 (rank : 121)	NC score	0.068180 (rank : 208)
Query Neighborhood Hits	118	Target Neighborhood Hits	582	Shared Neighborhood Hits	21
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

APOA_HUMAN
θ value	θ > 10 (rank : 122)	NC score	0.055086 (rank : 322)
Query Neighborhood Hits	118	Target Neighborhood Hits	221	Shared Neighborhood Hits	16
SwissProt Accessions	P08519	Gene names	LPA
Domain Architecture
Description	Apolipoprotein(a) precursor (EC 3.4.21.-) (Apo(a)) (Lp(a)).

APOH_HUMAN
θ value	θ > 10 (rank : 123)	NC score	0.080422 (rank : 154)
Query Neighborhood Hits	118	Target Neighborhood Hits	75	Shared Neighborhood Hits	15
SwissProt Accessions	P02749, Q9UCN7	Gene names	APOH, B2G1
Domain Architecture
Description	Beta-2-glycoprotein 1 precursor (Beta-2-glycoprotein I) (Apolipoprotein H) (Apo-H) (B2GPI) (Beta(2)GPI) (Activated protein C- binding protein) (APC inhibitor) (Anticardiolipin cofactor).

APOH_MOUSE
θ value	θ > 10 (rank : 124)	NC score	0.069363 (rank : 201)
Query Neighborhood Hits	118	Target Neighborhood Hits	74	Shared Neighborhood Hits	13
SwissProt Accessions	Q01339	Gene names	Apoh, B2gp1
Domain Architecture
Description	Beta-2-glycoprotein 1 precursor (Beta-2-glycoprotein I) (Apolipoprotein H) (Apo-H) (B2GPI) (Beta(2)GPI) (Activated protein C- binding protein) (APC inhibitor).

ASTL_HUMAN
θ value	θ > 10 (rank : 125)	NC score	0.114582 (rank : 108)
Query Neighborhood Hits	118	Target Neighborhood Hits	252	Shared Neighborhood Hits	7
SwissProt Accessions	Q6HA08	Gene names	ASTL
Domain Architecture	No domain graphic available
Description	Astacin-like metalloendopeptidase precursor (EC 3.4.-.-) (Oocyte astacin) (Ovastacin).

ASTL_MOUSE
θ value	θ > 10 (rank : 126)	NC score	0.118628 (rank : 103)
Query Neighborhood Hits	118	Target Neighborhood Hits	20	Shared Neighborhood Hits	6
SwissProt Accessions	Q6HA09, Q8BMA1	Gene names	Astl
Domain Architecture	No domain graphic available
Description	Astacin-like metalloendopeptidase precursor (EC 3.4.-.-) (Oocyte astacin) (Ovastacin).

BSSP4_HUMAN
θ value	θ > 10 (rank : 127)	NC score	0.059567 (rank : 262)
Query Neighborhood Hits	118	Target Neighborhood Hits	176	Shared Neighborhood Hits	14
SwissProt Accessions	Q9GZN4, O43342, Q6UXE0	Gene names	PRSS22, BSSP4, PRSS26
Domain Architecture
Description	Brain-specific serine protease 4 precursor (EC 3.4.21.-) (BSSP-4) (Serine protease 22) (Tryptase epsilon).

BSSP4_MOUSE
θ value	θ > 10 (rank : 128)	NC score	0.060316 (rank : 251)
Query Neighborhood Hits	118	Target Neighborhood Hits	179	Shared Neighborhood Hits	14
SwissProt Accessions	Q9ER10	Gene names	Prss22, Bssp4, Prss26
Domain Architecture
Description	Brain-specific serine protease 4 precursor (EC 3.4.21.-) (BSSP-4) (Serine protease 22) (Tryptase epsilon).

C163A_HUMAN
θ value	θ > 10 (rank : 129)	NC score	0.050585 (rank : 377)
Query Neighborhood Hits	118	Target Neighborhood Hits	54	Shared Neighborhood Hits	5
SwissProt Accessions	Q86VB7, Q07898, Q07899, Q07900, Q07901, Q2VLH7	Gene names	CD163, M130
Domain Architecture	No domain graphic available
Description	Scavenger receptor cysteine-rich type 1 protein M130 precursor (CD163 antigen) (Hemoglobin scavenger receptor) [Contains: Soluble CD163 (sCD163)].

C163A_MOUSE
θ value	θ > 10 (rank : 130)	NC score	0.051228 (rank : 372)
Query Neighborhood Hits	118	Target Neighborhood Hits	48	Shared Neighborhood Hits	5
SwissProt Accessions	Q2VLH6, Q2VLH5, Q99MX8	Gene names	Cd163, M130
Domain Architecture	No domain graphic available
Description	Scavenger receptor cysteine-rich type 1 protein M130 precursor (CD163 antigen) [Contains: Soluble CD163 (sCD163)].

C163B_HUMAN
θ value	θ > 10 (rank : 131)	NC score	0.051266 (rank : 371)
Query Neighborhood Hits	118	Target Neighborhood Hits	64	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NR16, Q6UWC2	Gene names	CD163L1, CD163B, M160
Domain Architecture	No domain graphic available
Description	Scavenger receptor cysteine-rich type 1 protein M160 precursor (CD163 antigen-like 1) (CD163b antigen).

C1QR1_HUMAN
θ value	θ > 10 (rank : 132)	NC score	0.059738 (rank : 258)
Query Neighborhood Hits	118	Target Neighborhood Hits	493	Shared Neighborhood Hits	32
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

C1QR1_MOUSE
θ value	θ > 10 (rank : 133)	NC score	0.076469 (rank : 172)
Query Neighborhood Hits	118	Target Neighborhood Hits	342	Shared Neighborhood Hits	31
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

C4BB_HUMAN
θ value	θ > 10 (rank : 134)	NC score	0.094881 (rank : 117)
Query Neighborhood Hits	118	Target Neighborhood Hits	77	Shared Neighborhood Hits	16
SwissProt Accessions	P20851	Gene names	C4BPB
Domain Architecture
Description	C4b-binding protein beta chain precursor.

C4BP_HUMAN
θ value	θ > 10 (rank : 135)	NC score	0.079622 (rank : 157)
Query Neighborhood Hits	118	Target Neighborhood Hits	92	Shared Neighborhood Hits	15
SwissProt Accessions	P04003	Gene names	C4BPA, C4BP
Domain Architecture
Description	C4b-binding protein alpha chain precursor (C4bp) (Proline-rich protein) (PRP).

C4BP_MOUSE
θ value	θ > 10 (rank : 136)	NC score	0.080294 (rank : 155)
Query Neighborhood Hits	118	Target Neighborhood Hits	91	Shared Neighborhood Hits	15
SwissProt Accessions	P08607	Gene names	C4bpa, C4bp
Domain Architecture
Description	C4b-binding protein precursor (C4bp).

CATG_MOUSE
θ value	θ > 10 (rank : 137)	NC score	0.051821 (rank : 361)
Query Neighborhood Hits	118	Target Neighborhood Hits	174	Shared Neighborhood Hits	14
SwissProt Accessions	P28293	Gene names	Ctsg
Domain Architecture
Description	Cathepsin G precursor (EC 3.4.21.20) (Vimentin-specific protease) (VSP).

CBPD_HUMAN
θ value	θ > 10 (rank : 138)	NC score	0.081075 (rank : 151)
Query Neighborhood Hits	118	Target Neighborhood Hits	53	Shared Neighborhood Hits	4
SwissProt Accessions	O75976, O15377, Q86SH9, Q86XE6	Gene names	CPD
Domain Architecture
Description	Carboxypeptidase D precursor (EC 3.4.17.22) (Metallocarboxypeptidase D) (gp180).

CBPD_MOUSE
θ value	θ > 10 (rank : 139)	NC score	0.081067 (rank : 152)
Query Neighborhood Hits	118	Target Neighborhood Hits	62	Shared Neighborhood Hits	4
SwissProt Accessions	O89001	Gene names	Cpd
Domain Architecture
Description	Carboxypeptidase D precursor (EC 3.4.17.22) (Metallocarboxypeptidase D) (gp180).

CBPE_HUMAN
θ value	θ > 10 (rank : 140)	NC score	0.094869 (rank : 118)
Query Neighborhood Hits	118	Target Neighborhood Hits	28	Shared Neighborhood Hits	5
SwissProt Accessions	P16870, Q9UIU9	Gene names	CPE
Domain Architecture
Description	Carboxypeptidase E precursor (EC 3.4.17.10) (CPE) (Carboxypeptidase H) (CPH) (Enkephalin convertase) (Prohormone-processing carboxypeptidase).

CBPE_MOUSE
θ value	θ > 10 (rank : 141)	NC score	0.094120 (rank : 122)
Query Neighborhood Hits	118	Target Neighborhood Hits	29	Shared Neighborhood Hits	4
SwissProt Accessions	Q00493, Q64439	Gene names	Cpe
Domain Architecture
Description	Carboxypeptidase E precursor (EC 3.4.17.10) (CPE) (Carboxypeptidase H) (CPH) (Enkephalin convertase) (Prohormone-processing carboxypeptidase).

CBPM_HUMAN
θ value	θ > 10 (rank : 142)	NC score	0.084306 (rank : 140)
Query Neighborhood Hits	118	Target Neighborhood Hits	33	Shared Neighborhood Hits	4
SwissProt Accessions	P14384, Q9H2K9	Gene names	CPM
Domain Architecture
Description	Carboxypeptidase M precursor (EC 3.4.17.12) (CPM).

CBPM_MOUSE
θ value	θ > 10 (rank : 143)	NC score	0.084627 (rank : 138)
Query Neighborhood Hits	118	Target Neighborhood Hits	30	Shared Neighborhood Hits	4
SwissProt Accessions	Q80V42, Q497S5, Q9CYH8	Gene names	Cpm
Domain Architecture	No domain graphic available
Description	Carboxypeptidase M precursor (EC 3.4.17.12) (CPM).

CBPN_HUMAN
θ value	θ > 10 (rank : 144)	NC score	0.092606 (rank : 126)
Query Neighborhood Hits	118	Target Neighborhood Hits	32	Shared Neighborhood Hits	4
SwissProt Accessions	P15169	Gene names	CPN1, ACBP
Domain Architecture
Description	Carboxypeptidase N catalytic chain precursor (EC 3.4.17.3) (CPN) (Carboxypeptidase N polypeptide 1) (Carboxypeptidase N small subunit) (Lysine carboxypeptidase) (Arginine carboxypeptidase) (Kininase-1) (Serum carboxypeptidase N) (SCPN) (Anaphylatoxin inactivator) (Plasma carboxypeptidase B).

CBPN_MOUSE
θ value	θ > 10 (rank : 145)	NC score	0.092934 (rank : 124)
Query Neighborhood Hits	118	Target Neighborhood Hits	26	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JJN5, Q91WM9	Gene names	Cpn1
Domain Architecture	No domain graphic available
Description	Carboxypeptidase N catalytic chain precursor (EC 3.4.17.3) (CPN) (Carboxypeptidase N polypeptide 1) (Carboxypeptidase N small subunit).

CBPZ_HUMAN
θ value	θ > 10 (rank : 146)	NC score	0.094144 (rank : 121)
Query Neighborhood Hits	118	Target Neighborhood Hits	69	Shared Neighborhood Hits	6
SwissProt Accessions	Q66K79, O00520, Q96MX2	Gene names	CPZ
Domain Architecture	No domain graphic available
Description	Carboxypeptidase Z precursor (EC 3.4.17.-) (CPZ).

CBPZ_MOUSE
θ value	θ > 10 (rank : 147)	NC score	0.092403 (rank : 127)
Query Neighborhood Hits	118	Target Neighborhood Hits	77	Shared Neighborhood Hits	6
SwissProt Accessions	Q8R4V4	Gene names	Cpz
Domain Architecture	No domain graphic available
Description	Carboxypeptidase Z precursor (EC 3.4.17.-) (CPZ).

CD248_HUMAN
θ value	θ > 10 (rank : 148)	NC score	0.056372 (rank : 303)
Query Neighborhood Hits	118	Target Neighborhood Hits	679	Shared Neighborhood Hits	31
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CD248_MOUSE
θ value	θ > 10 (rank : 149)	NC score	0.062019 (rank : 238)
Query Neighborhood Hits	118	Target Neighborhood Hits	578	Shared Neighborhood Hits	33
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CD320_HUMAN
θ value	θ > 10 (rank : 150)	NC score	0.055347 (rank : 319)
Query Neighborhood Hits	118	Target Neighborhood Hits	103	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NPF0, Q53HF7	Gene names	CD320, 8D6A
Domain Architecture	No domain graphic available
Description	CD320 antigen precursor (8D6 antigen) (FDC-signaling molecule 8D6) (FDC-SM-8D6).

CD97_HUMAN
θ value	θ > 10 (rank : 151)	NC score	0.050016 (rank : 381)
Query Neighborhood Hits	118	Target Neighborhood Hits	353	Shared Neighborhood Hits	27
SwissProt Accessions	P48960, O00718, O76101, Q8NG72, Q8TBQ7	Gene names	CD97
Domain Architecture
Description	CD97 antigen precursor (Leukocyte antigen CD97).

CERU_HUMAN
θ value	θ > 10 (rank : 152)	NC score	0.117557 (rank : 105)
Query Neighborhood Hits	118	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	P00450, Q14063, Q2PP18, Q9UKS4	Gene names	CP
Domain Architecture
Description	Ceruloplasmin precursor (EC 1.16.3.1) (Ferroxidase).

CERU_MOUSE
θ value	θ > 10 (rank : 153)	NC score	0.116361 (rank : 107)
Query Neighborhood Hits	118	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	Q61147	Gene names	Cp
Domain Architecture
Description	Ceruloplasmin precursor (EC 1.16.3.1) (Ferroxidase).

CFAB_HUMAN
θ value	θ > 10 (rank : 154)	NC score	0.083877 (rank : 143)
Query Neighborhood Hits	118	Target Neighborhood Hits	251	Shared Neighborhood Hits	23
SwissProt Accessions	P00751, O15006, Q29944, Q96HX6, Q9BTF5, Q9BX92	Gene names	CFB, BF
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) (Properdin factor B) (Glycine-rich beta glycoprotein) (GBG) (PBF2) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

CFAB_MOUSE
θ value	θ > 10 (rank : 155)	NC score	0.085060 (rank : 136)
Query Neighborhood Hits	118	Target Neighborhood Hits	262	Shared Neighborhood Hits	23
SwissProt Accessions	P04186	Gene names	Cfb, Bf, H2-Bf
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

CFAD_HUMAN
θ value	θ > 10 (rank : 156)	NC score	0.052546 (rank : 351)
Query Neighborhood Hits	118	Target Neighborhood Hits	176	Shared Neighborhood Hits	14
SwissProt Accessions	P00746	Gene names	CFD, DF
Domain Architecture
Description	Complement factor D precursor (EC 3.4.21.46) (C3 convertase activator) (Properdin factor D) (Adipsin).

CFAD_MOUSE
θ value	θ > 10 (rank : 157)	NC score	0.052806 (rank : 348)
Query Neighborhood Hits	118	Target Neighborhood Hits	177	Shared Neighborhood Hits	14
SwissProt Accessions	P03953, Q61280	Gene names	Cfd, Adn, Df
Domain Architecture
Description	Complement factor D precursor (EC 3.4.21.46) (C3 convertase activator) (Properdin factor D) (Adipsin) (28 kDa adipocyte protein).

CFAH_HUMAN
θ value	θ > 10 (rank : 158)	NC score	0.073387 (rank : 187)
Query Neighborhood Hits	118	Target Neighborhood Hits	101	Shared Neighborhood Hits	15
SwissProt Accessions	P08603, P78435, Q14570, Q38G77, Q5TFM3, Q8N708, Q9NU86	Gene names	CFH, HF, HF1
Domain Architecture
Description	Complement factor H precursor (H factor 1).

CFAH_MOUSE
θ value	θ > 10 (rank : 159)	NC score	0.073075 (rank : 188)
Query Neighborhood Hits	118	Target Neighborhood Hits	112	Shared Neighborhood Hits	15
SwissProt Accessions	P06909	Gene names	Cfh, Hf1
Domain Architecture
Description	Complement factor H precursor (Protein beta-1-H).

CFAI_HUMAN
θ value	θ > 10 (rank : 160)	NC score	0.078737 (rank : 162)
Query Neighborhood Hits	118	Target Neighborhood Hits	289	Shared Neighborhood Hits	28
SwissProt Accessions	P05156, O60442	Gene names	CFI, IF
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

CFAI_MOUSE
θ value	θ > 10 (rank : 161)	NC score	0.081517 (rank : 149)
Query Neighborhood Hits	118	Target Neighborhood Hits	290	Shared Neighborhood Hits	27
SwissProt Accessions	Q61129, Q9WU07	Gene names	Cfi, If
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

CLCR_HUMAN
θ value	θ > 10 (rank : 162)	NC score	0.059025 (rank : 272)
Query Neighborhood Hits	118	Target Neighborhood Hits	177	Shared Neighborhood Hits	14
SwissProt Accessions	Q99895, O00765, Q9NUH5	Gene names	CTRC, CLCR
Domain Architecture
Description	Caldecrin precursor (EC 3.4.21.2) (Chymotrypsin C).

CO2_HUMAN
θ value	θ > 10 (rank : 163)	NC score	0.076814 (rank : 170)
Query Neighborhood Hits	118	Target Neighborhood Hits	258	Shared Neighborhood Hits	18
SwissProt Accessions	P06681, O19694, Q13904	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

CO2_MOUSE
θ value	θ > 10 (rank : 164)	NC score	0.079594 (rank : 158)
Query Neighborhood Hits	118	Target Neighborhood Hits	250	Shared Neighborhood Hits	19
SwissProt Accessions	P21180	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

CO6_HUMAN
θ value	θ > 10 (rank : 165)	NC score	0.056265 (rank : 306)
Query Neighborhood Hits	118	Target Neighborhood Hits	331	Shared Neighborhood Hits	30
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

CORIN_HUMAN
θ value	θ > 10 (rank : 166)	NC score	0.077664 (rank : 167)
Query Neighborhood Hits	118	Target Neighborhood Hits	453	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y5Q5, Q9UHY2	Gene names	CORIN, CRN, TMPRSS10
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Heart-specific serine proteinase ATC2) (Transmembrane protease, serine 10).

CORIN_MOUSE
θ value	θ > 10 (rank : 167)	NC score	0.076188 (rank : 175)
Query Neighborhood Hits	118	Target Neighborhood Hits	451	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Z319	Gene names	Corin, Crn, Lrp4
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4).

CR1_HUMAN
θ value	θ > 10 (rank : 168)	NC score	0.081761 (rank : 148)
Query Neighborhood Hits	118	Target Neighborhood Hits	108	Shared Neighborhood Hits	15
SwissProt Accessions	P17927, Q16745, Q9UQV2	Gene names	CR1, C3BR
Domain Architecture
Description	Complement receptor type 1 precursor (C3b/C4b receptor) (CD35 antigen).

CR2_HUMAN
θ value	θ > 10 (rank : 169)	NC score	0.087024 (rank : 133)
Query Neighborhood Hits	118	Target Neighborhood Hits	89	Shared Neighborhood Hits	15
SwissProt Accessions	P20023, Q13866, Q14212	Gene names	CR2, C3DR
Domain Architecture
Description	Complement receptor type 2 precursor (Cr2) (Complement C3d receptor) (Epstein-Barr virus receptor) (EBV receptor) (CD21 antigen).

CR2_MOUSE
θ value	θ > 10 (rank : 170)	NC score	0.086392 (rank : 135)
Query Neighborhood Hits	118	Target Neighborhood Hits	101	Shared Neighborhood Hits	15
SwissProt Accessions	P19070	Gene names	Cr2
Domain Architecture
Description	Complement receptor type 2 precursor (Cr2) (Complement C3d receptor) (CD21 antigen).

CRRY_MOUSE
θ value	θ > 10 (rank : 171)	NC score	0.072399 (rank : 192)
Query Neighborhood Hits	118	Target Neighborhood Hits	84	Shared Neighborhood Hits	15
SwissProt Accessions	Q64735, Q3TV30, Q58E68, Q61447, Q61449, Q8CF59, Q8K328	Gene names	Crry, Cry
Domain Architecture	No domain graphic available
Description	Complement regulatory protein Crry precursor (Protein p65).

CRUM1_HUMAN
θ value	θ > 10 (rank : 172)	NC score	0.075814 (rank : 176)
Query Neighborhood Hits	118	Target Neighborhood Hits	457	Shared Neighborhood Hits	34
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

CRUM1_MOUSE
θ value	θ > 10 (rank : 173)	NC score	0.073511 (rank : 186)
Query Neighborhood Hits	118	Target Neighborhood Hits	444	Shared Neighborhood Hits	34
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

CRUM2_HUMAN
θ value	θ > 10 (rank : 174)	NC score	0.071410 (rank : 197)
Query Neighborhood Hits	118	Target Neighborhood Hits	453	Shared Neighborhood Hits	36
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

CSPG2_HUMAN
θ value	θ > 10 (rank : 175)	NC score	0.058460 (rank : 280)
Query Neighborhood Hits	118	Target Neighborhood Hits	681	Shared Neighborhood Hits	29
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

CSPG2_MOUSE
θ value	θ > 10 (rank : 176)	NC score	0.058560 (rank : 278)
Query Neighborhood Hits	118	Target Neighborhood Hits	711	Shared Neighborhood Hits	26
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

CSPG3_HUMAN
θ value	θ > 10 (rank : 177)	NC score	0.058812 (rank : 275)
Query Neighborhood Hits	118	Target Neighborhood Hits	676	Shared Neighborhood Hits	24
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

CSPG3_MOUSE
θ value	θ > 10 (rank : 178)	NC score	0.062333 (rank : 235)
Query Neighborhood Hits	118	Target Neighborhood Hits	657	Shared Neighborhood Hits	25
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

CTRB1_HUMAN
θ value	θ > 10 (rank : 179)	NC score	0.056280 (rank : 305)
Query Neighborhood Hits	118	Target Neighborhood Hits	176	Shared Neighborhood Hits	14
SwissProt Accessions	P17538	Gene names	CTRB1, CTRB
Domain Architecture
Description	Chymotrypsinogen B precursor (EC 3.4.21.1) [Contains: Chymotrypsin B chain A; Chymotrypsin B chain B; Chymotrypsin B chain C].

CTRL_HUMAN
θ value	θ > 10 (rank : 180)	NC score	0.058363 (rank : 282)
Query Neighborhood Hits	118	Target Neighborhood Hits	179	Shared Neighborhood Hits	14
SwissProt Accessions	P40313	Gene names	CTRL, CTRL1
Domain Architecture
Description	Chymotrypsin-like protease CTRL-1 precursor (EC 3.4.21.-).

DAF1_MOUSE
θ value	θ > 10 (rank : 181)	NC score	0.067455 (rank : 212)
Query Neighborhood Hits	118	Target Neighborhood Hits	204	Shared Neighborhood Hits	17
SwissProt Accessions	Q61475, P97732, Q61397	Gene names	Cd55a, Daf1
Domain Architecture
Description	Complement decay-accelerating factor, GPI-anchored precursor (DAF-GPI) (CD55 antigen).

DAF2_MOUSE
θ value	θ > 10 (rank : 182)	NC score	0.067624 (rank : 210)
Query Neighborhood Hits	118	Target Neighborhood Hits	114	Shared Neighborhood Hits	15
SwissProt Accessions	Q61476	Gene names	Cd55b, Daf2
Domain Architecture
Description	Complement decay-accelerating factor transmembrane isoform precursor (DAF-TM) (CD55 antigen).

DAF_HUMAN
θ value	θ > 10 (rank : 183)	NC score	0.073712 (rank : 185)
Query Neighborhood Hits	118	Target Neighborhood Hits	97	Shared Neighborhood Hits	15
SwissProt Accessions	P08174, P09679, P78361	Gene names	CD55, CR, DAF
Domain Architecture
Description	Complement decay-accelerating factor precursor (CD55 antigen).

DESC4_MOUSE
θ value	θ > 10 (rank : 184)	NC score	0.061570 (rank : 240)
Query Neighborhood Hits	118	Target Neighborhood Hits	176	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BZ10, Q8BZ04	Gene names	Desc4
Domain Architecture	No domain graphic available
Description	Serine protease DESC4 precursor (EC 3.4.21.-) [Contains: Serine protease DESC4 non-catalytic chain; Serine protease DESC4 catalytic chain].

DLK_HUMAN
θ value	θ > 10 (rank : 185)	NC score	0.055631 (rank : 312)
Query Neighborhood Hits	118	Target Neighborhood Hits	401	Shared Neighborhood Hits	23
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

DLK_MOUSE
θ value	θ > 10 (rank : 186)	NC score	0.054981 (rank : 326)
Query Neighborhood Hits	118	Target Neighborhood Hits	374	Shared Neighborhood Hits	19
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

DLL1_HUMAN
θ value	θ > 10 (rank : 187)	NC score	0.059456 (rank : 264)
Query Neighborhood Hits	118	Target Neighborhood Hits	455	Shared Neighborhood Hits	33
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

DLL1_MOUSE
θ value	θ > 10 (rank : 188)	NC score	0.060332 (rank : 249)
Query Neighborhood Hits	118	Target Neighborhood Hits	456	Shared Neighborhood Hits	33
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

DLL3_HUMAN
θ value	θ > 10 (rank : 189)	NC score	0.054834 (rank : 329)
Query Neighborhood Hits	118	Target Neighborhood Hits	419	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

DLL3_MOUSE
θ value	θ > 10 (rank : 190)	NC score	0.055263 (rank : 320)
Query Neighborhood Hits	118	Target Neighborhood Hits	399	Shared Neighborhood Hits	21
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

DLL4_HUMAN
θ value	θ > 10 (rank : 191)	NC score	0.051545 (rank : 366)
Query Neighborhood Hits	118	Target Neighborhood Hits	435	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

DLL4_MOUSE
θ value	θ > 10 (rank : 192)	NC score	0.051529 (rank : 367)
Query Neighborhood Hits	118	Target Neighborhood Hits	440	Shared Neighborhood Hits	26
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

DNER_HUMAN
θ value	θ > 10 (rank : 193)	NC score	0.052191 (rank : 357)
Query Neighborhood Hits	118	Target Neighborhood Hits	460	Shared Neighborhood Hits	25
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

DNER_MOUSE
θ value	θ > 10 (rank : 194)	NC score	0.051969 (rank : 360)
Query Neighborhood Hits	118	Target Neighborhood Hits	413	Shared Neighborhood Hits	24
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

EGFL7_HUMAN
θ value	θ > 10 (rank : 195)	NC score	0.079274 (rank : 159)
Query Neighborhood Hits	118	Target Neighborhood Hits	325	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

EGFL7_MOUSE
θ value	θ > 10 (rank : 196)	NC score	0.055236 (rank : 321)
Query Neighborhood Hits	118	Target Neighborhood Hits	287	Shared Neighborhood Hits	19
SwissProt Accessions	Q9QXT5, Q6XD35, Q9DCP5	Gene names	Egfl7, Megf7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (Zneu1).

EGFL8_HUMAN
θ value	θ > 10 (rank : 197)	NC score	0.071773 (rank : 194)
Query Neighborhood Hits	118	Target Neighborhood Hits	270	Shared Neighborhood Hits	26
SwissProt Accessions	Q99944, Q8IV30	Gene names	EGFL8, C6orf8, NG3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8) (Vascular endothelial-statin 2) (VE-statin-2).

EGFL8_MOUSE
θ value	θ > 10 (rank : 198)	NC score	0.075340 (rank : 178)
Query Neighborhood Hits	118	Target Neighborhood Hits	266	Shared Neighborhood Hits	26
SwissProt Accessions	Q6GUQ1, O35447	Gene names	Egfl8, Ng3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8).

EGFL9_MOUSE
θ value	θ > 10 (rank : 199)	NC score	0.051589 (rank : 365)
Query Neighborhood Hits	118	Target Neighborhood Hits	379	Shared Neighborhood Hits	22
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

EGF_MOUSE
θ value	θ > 10 (rank : 200)	NC score	0.057579 (rank : 290)
Query Neighborhood Hits	118	Target Neighborhood Hits	358	Shared Neighborhood Hits	27
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

ELA2A_HUMAN
θ value	θ > 10 (rank : 201)	NC score	0.055815 (rank : 310)
Query Neighborhood Hits	118	Target Neighborhood Hits	180	Shared Neighborhood Hits	14
SwissProt Accessions	P08217, Q14243	Gene names	ELA2A
Domain Architecture
Description	Elastase-2A precursor (EC 3.4.21.71).

ELA2A_MOUSE
θ value	θ > 10 (rank : 202)	NC score	0.056335 (rank : 304)
Query Neighborhood Hits	118	Target Neighborhood Hits	178	Shared Neighborhood Hits	14
SwissProt Accessions	P05208	Gene names	Ela2a, Ela-2, Ela2
Domain Architecture
Description	Elastase-2A precursor (EC 3.4.21.71) (Elastase-2).

ELA2B_HUMAN
θ value	θ > 10 (rank : 203)	NC score	0.054306 (rank : 334)
Query Neighborhood Hits	118	Target Neighborhood Hits	178	Shared Neighborhood Hits	14
SwissProt Accessions	P08218	Gene names	ELA2B
Domain Architecture
Description	Elastase-2B precursor (EC 3.4.21.71).

F13B_HUMAN
θ value	θ > 10 (rank : 204)	NC score	0.054657 (rank : 332)
Query Neighborhood Hits	118	Target Neighborhood Hits	84	Shared Neighborhood Hits	13
SwissProt Accessions	P05160	Gene names	F13B
Domain Architecture
Description	Coagulation factor XIII B chain precursor (Protein-glutamine gamma- glutamyltransferase B chain) (Transglutaminase B chain) (Fibrin- stabilizing factor B subunit).

F13B_MOUSE
θ value	θ > 10 (rank : 205)	NC score	0.062653 (rank : 229)
Query Neighborhood Hits	118	Target Neighborhood Hits	93	Shared Neighborhood Hits	14
SwissProt Accessions	Q07968	Gene names	F13b, Cf13b
Domain Architecture
Description	Coagulation factor XIII B chain precursor (Protein-glutamine gamma- glutamyltransferase B chain) (Transglutaminase B chain).

FA10_HUMAN
θ value	θ > 10 (rank : 206)	NC score	0.089243 (rank : 131)
Query Neighborhood Hits	118	Target Neighborhood Hits	431	Shared Neighborhood Hits	36
SwissProt Accessions	P00742, Q14340	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) (Stuart- Prower factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

FA10_MOUSE
θ value	θ > 10 (rank : 207)	NC score	0.084230 (rank : 141)
Query Neighborhood Hits	118	Target Neighborhood Hits	435	Shared Neighborhood Hits	33
SwissProt Accessions	O88947, O54740, Q99L32	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

FA11_HUMAN
θ value	θ > 10 (rank : 208)	NC score	0.060966 (rank : 246)
Query Neighborhood Hits	118	Target Neighborhood Hits	178	Shared Neighborhood Hits	14
SwissProt Accessions	P03951, Q9Y495	Gene names	F11
Domain Architecture
Description	Coagulation factor XI precursor (EC 3.4.21.27) (Plasma thromboplastin antecedent) (PTA) (FXI) [Contains: Coagulation factor XIa heavy chain; Coagulation factor XIa light chain].

FA11_MOUSE
θ value	θ > 10 (rank : 209)	NC score	0.059418 (rank : 265)
Query Neighborhood Hits	118	Target Neighborhood Hits	180	Shared Neighborhood Hits	14
SwissProt Accessions	Q91Y47	Gene names	F11
Domain Architecture
Description	Coagulation factor XI precursor (EC 3.4.21.27) (Plasma thromboplastin antecedent) (PTA) (FXI) [Contains: Coagulation factor XIa heavy chain; Coagulation factor XIa light chain].

FA12_HUMAN
θ value	θ > 10 (rank : 210)	NC score	0.075484 (rank : 177)
Query Neighborhood Hits	118	Target Neighborhood Hits	425	Shared Neighborhood Hits	32
SwissProt Accessions	P00748, P78339	Gene names	F12
Domain Architecture
Description	Coagulation factor XII precursor (EC 3.4.21.38) (Hageman factor) (HAF) [Contains: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Beta-factor XIIa part 2; Coagulation factor XIIa light chain].

FA7_HUMAN
θ value	θ > 10 (rank : 211)	NC score	0.084133 (rank : 142)
Query Neighborhood Hits	118	Target Neighborhood Hits	404	Shared Neighborhood Hits	35
SwissProt Accessions	P08709, Q14339, Q5JVF2	Gene names	F7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) (SPCA) (Proconvertin) (Eptacog alfa) [Contains: Factor VII light chain; Factor VII heavy chain].

FA7_MOUSE
θ value	θ > 10 (rank : 212)	NC score	0.084327 (rank : 139)
Query Neighborhood Hits	118	Target Neighborhood Hits	374	Shared Neighborhood Hits	34
SwissProt Accessions	P70375, Q61109	Gene names	F7, Cf7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) [Contains: Factor VII light chain; Factor VII heavy chain].

FA9_HUMAN
θ value	θ > 10 (rank : 213)	NC score	0.088857 (rank : 132)
Query Neighborhood Hits	118	Target Neighborhood Hits	421	Shared Neighborhood Hits	38
SwissProt Accessions	P00740	Gene names	F9
Domain Architecture
Description	Coagulation factor IX precursor (EC 3.4.21.22) (Christmas factor) (Plasma thromboplastin component) (PTC) [Contains: Coagulation factor IXa light chain; Coagulation factor IXa heavy chain].

FBLN1_HUMAN
θ value	θ > 10 (rank : 214)	NC score	0.058225 (rank : 284)
Query Neighborhood Hits	118	Target Neighborhood Hits	324	Shared Neighborhood Hits	29
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

FBLN1_MOUSE
θ value	θ > 10 (rank : 215)	NC score	0.053502 (rank : 342)
Query Neighborhood Hits	118	Target Neighborhood Hits	329	Shared Neighborhood Hits	26
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

FBLN2_HUMAN
θ value	θ > 10 (rank : 216)	NC score	0.057020 (rank : 296)
Query Neighborhood Hits	118	Target Neighborhood Hits	392	Shared Neighborhood Hits	26
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

FBLN2_MOUSE
θ value	θ > 10 (rank : 217)	NC score	0.054746 (rank : 330)
Query Neighborhood Hits	118	Target Neighborhood Hits	505	Shared Neighborhood Hits	27
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

FBLN3_HUMAN
θ value	θ > 10 (rank : 218)	NC score	0.053085 (rank : 344)
Query Neighborhood Hits	118	Target Neighborhood Hits	293	Shared Neighborhood Hits	25
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

FBLN4_HUMAN
θ value	θ > 10 (rank : 219)	NC score	0.052601 (rank : 350)
Query Neighborhood Hits	118	Target Neighborhood Hits	278	Shared Neighborhood Hits	23
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

FBLN4_MOUSE
θ value	θ > 10 (rank : 220)	NC score	0.051302 (rank : 370)
Query Neighborhood Hits	118	Target Neighborhood Hits	270	Shared Neighborhood Hits	23
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

FBLN5_HUMAN
θ value	θ > 10 (rank : 221)	NC score	0.063682 (rank : 221)
Query Neighborhood Hits	118	Target Neighborhood Hits	329	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

FBLN5_MOUSE
θ value	θ > 10 (rank : 222)	NC score	0.063487 (rank : 223)
Query Neighborhood Hits	118	Target Neighborhood Hits	317	Shared Neighborhood Hits	25
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

FBN1_HUMAN
θ value	θ > 10 (rank : 223)	NC score	0.063212 (rank : 224)
Query Neighborhood Hits	118	Target Neighborhood Hits	557	Shared Neighborhood Hits	39
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

FBN1_MOUSE
θ value	θ > 10 (rank : 224)	NC score	0.062107 (rank : 237)
Query Neighborhood Hits	118	Target Neighborhood Hits	563	Shared Neighborhood Hits	38
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

FBN2_HUMAN
θ value	θ > 10 (rank : 225)	NC score	0.059276 (rank : 268)
Query Neighborhood Hits	118	Target Neighborhood Hits	560	Shared Neighborhood Hits	36
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN2_MOUSE
θ value	θ > 10 (rank : 226)	NC score	0.059874 (rank : 255)
Query Neighborhood Hits	118	Target Neighborhood Hits	549	Shared Neighborhood Hits	38
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN3_HUMAN
θ value	θ > 10 (rank : 227)	NC score	0.062230 (rank : 236)
Query Neighborhood Hits	118	Target Neighborhood Hits	543	Shared Neighborhood Hits	39
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

FHR3_HUMAN
θ value	θ > 10 (rank : 228)	NC score	0.060796 (rank : 248)
Query Neighborhood Hits	118	Target Neighborhood Hits	74	Shared Neighborhood Hits	14
SwissProt Accessions	Q02985, Q9UJ16	Gene names	CFHL3, FHR3
Domain Architecture
Description	Complement factor H-related protein 3 precursor (FHR-3) (H factor-like protein 3) (DOWN16).

FHR4_HUMAN
θ value	θ > 10 (rank : 229)	NC score	0.069425 (rank : 200)
Query Neighborhood Hits	118	Target Neighborhood Hits	75	Shared Neighborhood Hits	15
SwissProt Accessions	Q92496, Q9UJY6	Gene names	CFHL4, FHR4
Domain Architecture
Description	Complement factor H-related protein 4 precursor (FHR-4).

FHR5_HUMAN
θ value	θ > 10 (rank : 230)	NC score	0.056866 (rank : 298)
Query Neighborhood Hits	118	Target Neighborhood Hits	77	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BXR6	Gene names	CFHL5, FHR5
Domain Architecture
Description	Complement factor H-related protein 5 precursor (FHR-5).

GAS6_HUMAN
θ value	θ > 10 (rank : 231)	NC score	0.077541 (rank : 169)
Query Neighborhood Hits	118	Target Neighborhood Hits	348	Shared Neighborhood Hits	34
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

GAS6_MOUSE
θ value	θ > 10 (rank : 232)	NC score	0.072651 (rank : 190)
Query Neighborhood Hits	118	Target Neighborhood Hits	343	Shared Neighborhood Hits	35
SwissProt Accessions	Q61592, Q99K57	Gene names	Gas6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

GLPC_HUMAN
θ value	θ > 10 (rank : 233)	NC score	0.108072 (rank : 110)
Query Neighborhood Hits	118	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	P04921, Q92642	Gene names	GYPC, GPC
Domain Architecture
Description	Glycophorin C (PAS-2') (Glycoprotein beta) (GLPC) (Glycoconnectin) (Sialoglycoprotein D) (Glycophorin D) (GPD) (CD236 antigen).

GRAH_HUMAN
θ value	θ > 10 (rank : 234)	NC score	0.052880 (rank : 347)
Query Neighborhood Hits	118	Target Neighborhood Hits	175	Shared Neighborhood Hits	14
SwissProt Accessions	P20718	Gene names	GZMH, CGL2, CTSGL2
Domain Architecture
Description	Granzyme H precursor (EC 3.4.21.-) (Cytotoxic T-lymphocyte proteinase) (Cathepsin G-like 2) (CTSGL2) (CCP-X) (Cytotoxic serine protease C) (CSP-C).

HABP2_HUMAN
θ value	θ > 10 (rank : 235)	NC score	0.084696 (rank : 137)
Query Neighborhood Hits	118	Target Neighborhood Hits	431	Shared Neighborhood Hits	31
SwissProt Accessions	Q14520, O00663	Gene names	HABP2, HGFAL, PHBP
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) (Hepatocyte growth factor activator-like protein) (Factor VII-activating protease) (Factor seven-activating protease) (FSAP) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

HABP2_MOUSE
θ value	θ > 10 (rank : 236)	NC score	0.083698 (rank : 144)
Query Neighborhood Hits	118	Target Neighborhood Hits	445	Shared Neighborhood Hits	31
SwissProt Accessions	Q8K0D2	Gene names	Habp2, Phbp
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

HEPH_HUMAN
θ value	θ > 10 (rank : 237)	NC score	0.116847 (rank : 106)
Query Neighborhood Hits	118	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BQS7, O75180, Q6UW45, Q9C058	Gene names	HEPH, KIAA0698
Domain Architecture	No domain graphic available
Description	Hephaestin precursor (EC 1.-.-.-).

HEPH_MOUSE
θ value	θ > 10 (rank : 238)	NC score	0.118439 (rank : 104)
Query Neighborhood Hits	118	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z0Z4, Q6ZQ65, Q80Y80, Q8C4S2	Gene names	Heph, Kiaa0698
Domain Architecture	No domain graphic available
Description	Hephaestin precursor (EC 1.-.-.-).

HEPS_HUMAN
θ value	θ > 10 (rank : 239)	NC score	0.062339 (rank : 234)
Query Neighborhood Hits	118	Target Neighborhood Hits	178	Shared Neighborhood Hits	14
SwissProt Accessions	P05981	Gene names	HPN, TMPRSS1
Domain Architecture
Description	Serine protease hepsin (EC 3.4.21.-) (Transmembrane protease, serine 1) [Contains: Serine protease hepsin non-catalytic chain; Serine protease hepsin catalytic chain].

HEPS_MOUSE
θ value	θ > 10 (rank : 240)	NC score	0.062946 (rank : 226)
Query Neighborhood Hits	118	Target Neighborhood Hits	178	Shared Neighborhood Hits	14
SwissProt Accessions	O35453, Q9CW97	Gene names	Hpn
Domain Architecture
Description	Serine protease hepsin (EC 3.4.21.-) [Contains: Serine protease hepsin non-catalytic chain; Serine protease hepsin catalytic chain].

HGFA_HUMAN
θ value	θ > 10 (rank : 241)	NC score	0.072575 (rank : 191)
Query Neighborhood Hits	118	Target Neighborhood Hits	436	Shared Neighborhood Hits	30
SwissProt Accessions	Q04756, Q14726	Gene names	HGFAC
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

HGFA_MOUSE
θ value	θ > 10 (rank : 242)	NC score	0.074567 (rank : 179)
Query Neighborhood Hits	118	Target Neighborhood Hits	419	Shared Neighborhood Hits	31
SwissProt Accessions	Q9R098, Q9JKV4	Gene names	Hgfac
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

HPTR_HUMAN
θ value	θ > 10 (rank : 243)	NC score	0.092187 (rank : 129)
Query Neighborhood Hits	118	Target Neighborhood Hits	166	Shared Neighborhood Hits	14
SwissProt Accessions	P00739, Q7LE20, Q92658, Q92659, Q9ULB0	Gene names	HPR
Domain Architecture
Description	Haptoglobin-related protein precursor.

HPT_HUMAN
θ value	θ > 10 (rank : 244)	NC score	0.094867 (rank : 119)
Query Neighborhood Hits	118	Target Neighborhood Hits	184	Shared Neighborhood Hits	16
SwissProt Accessions	P00738, P00737, Q2PP15, Q3B7J0, Q6LBY9	Gene names	HP
Domain Architecture
Description	Haptoglobin precursor [Contains: Haptoglobin alpha chain; Haptoglobin beta chain].

HPT_MOUSE
θ value	θ > 10 (rank : 245)	NC score	0.094210 (rank : 120)
Query Neighborhood Hits	118	Target Neighborhood Hits	178	Shared Neighborhood Hits	15
SwissProt Accessions	Q61646	Gene names	Hp
Domain Architecture
Description	Haptoglobin precursor [Contains: Haptoglobin alpha chain; Haptoglobin beta chain].

JAG1_HUMAN
θ value	θ > 10 (rank : 246)	NC score	0.059159 (rank : 269)
Query Neighborhood Hits	118	Target Neighborhood Hits	514	Shared Neighborhood Hits	38
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

JAG1_MOUSE
θ value	θ > 10 (rank : 247)	NC score	0.058409 (rank : 281)
Query Neighborhood Hits	118	Target Neighborhood Hits	518	Shared Neighborhood Hits	36
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

JAG2_HUMAN
θ value	θ > 10 (rank : 248)	NC score	0.061123 (rank : 245)
Query Neighborhood Hits	118	Target Neighborhood Hits	491	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

JAG2_MOUSE
θ value	θ > 10 (rank : 249)	NC score	0.058569 (rank : 277)
Query Neighborhood Hits	118	Target Neighborhood Hits	504	Shared Neighborhood Hits	31
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

K1KB1_MOUSE
θ value	θ > 10 (rank : 250)	NC score	0.051044 (rank : 373)
Query Neighborhood Hits	118	Target Neighborhood Hits	180	Shared Neighborhood Hits	16
SwissProt Accessions	P00755	Gene names	Klk1b1, Klk-1, Klk1
Domain Architecture
Description	Kallikrein 1-related peptidase b1 precursor (EC 3.4.21.35) (Glandular kallikrein K1) (Tissue kallikrein-1) (mGK-1).

K1KB9_MOUSE
θ value	θ > 10 (rank : 251)	NC score	0.051672 (rank : 363)
Query Neighborhood Hits	118	Target Neighborhood Hits	176	Shared Neighborhood Hits	14
SwissProt Accessions	P15949	Gene names	Klk1b9, Egfbp3, Klk-9, Klk9
Domain Architecture
Description	Kallikrein 1-related peptidase b9 precursor (EC 3.4.21.35) (Tissue kallikrein-9) (Glandular kallikrein K9) (mGK-9) (Epidermal growth factor-binding protein type C) (EGF-BP C).

KLK10_HUMAN
θ value	θ > 10 (rank : 252)	NC score	0.052213 (rank : 355)
Query Neighborhood Hits	118	Target Neighborhood Hits	178	Shared Neighborhood Hits	15
SwissProt Accessions	O43240, Q99920, Q9GZW9	Gene names	KLK10, NES1, PRRSL1
Domain Architecture
Description	Kallikrein-10 precursor (EC 3.4.21.-) (Protease serine-like 1) (Normal epithelial cell-specific 1).

KLK11_HUMAN
θ value	θ > 10 (rank : 253)	NC score	0.051782 (rank : 362)
Query Neighborhood Hits	118	Target Neighborhood Hits	174	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UBX7, O75837, Q9NS65	Gene names	KLK11, PRSS20, TLSP
Domain Architecture
Description	Kallikrein-11 precursor (EC 3.4.21.-) (Hippostasin) (Trypsin-like protease).

KLK12_HUMAN
θ value	θ > 10 (rank : 254)	NC score	0.052422 (rank : 352)
Query Neighborhood Hits	118	Target Neighborhood Hits	197	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UKR0, Q9UKR1	Gene names	KLK12, KLKL5
Domain Architecture
Description	Kallikrein-12 precursor (EC 3.4.21.-) (Kallikrein-like protein 5) (KLK-L5).

KLK13_HUMAN
θ value	θ > 10 (rank : 255)	NC score	0.052208 (rank : 356)
Query Neighborhood Hits	118	Target Neighborhood Hits	179	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UKR3, Q9Y433	Gene names	KLK13, KLKL4
Domain Architecture
Description	Kallikrein-13 precursor (EC 3.4.21.-) (Kallikrein-like protein 4) (KLK-L4).

KLK14_HUMAN
θ value	θ > 10 (rank : 256)	NC score	0.053754 (rank : 339)
Query Neighborhood Hits	118	Target Neighborhood Hits	179	Shared Neighborhood Hits	14
SwissProt Accessions	Q9P0G3	Gene names	KLK14, KLKL6
Domain Architecture
Description	Kallikrein-14 precursor (EC 3.4.21.-) (Kallikrein-like protein 6) (KLK-L6).

KLK15_HUMAN
θ value	θ > 10 (rank : 257)	NC score	0.050342 (rank : 380)
Query Neighborhood Hits	118	Target Neighborhood Hits	180	Shared Neighborhood Hits	14
SwissProt Accessions	Q9H2R5, Q15358, Q9H2R3, Q9H2R4, Q9H2R6, Q9HBG9	Gene names	KLK15
Domain Architecture
Description	Kallikrein-15 precursor (EC 3.4.21.-) (ACO protease).

KLK1_MOUSE
θ value	θ > 10 (rank : 258)	NC score	0.050896 (rank : 374)
Query Neighborhood Hits	118	Target Neighborhood Hits	179	Shared Neighborhood Hits	14
SwissProt Accessions	P15947, Q61855	Gene names	Klk1, Klk-6, Klk6
Domain Architecture
Description	Glandular kallikrein K1 precursor (EC 3.4.21.35) (Tissue kallikrein-6) (mGK-6) (Renal kallikrein) (KAL-B).

KLK6_HUMAN
θ value	θ > 10 (rank : 259)	NC score	0.054919 (rank : 327)
Query Neighborhood Hits	118	Target Neighborhood Hits	175	Shared Neighborhood Hits	14
SwissProt Accessions	Q92876	Gene names	KLK6, PRSS18, PRSS9
Domain Architecture
Description	Kallikrein-6 precursor (EC 3.4.21.-) (Protease M) (Neurosin) (Zyme) (SP59).

KLK7_HUMAN
θ value	θ > 10 (rank : 260)	NC score	0.051638 (rank : 364)
Query Neighborhood Hits	118	Target Neighborhood Hits	175	Shared Neighborhood Hits	14
SwissProt Accessions	P49862, Q8N5N9, Q8NFV7	Gene names	KLK7, PRSS6, SCCE
Domain Architecture
Description	Kallikrein-7 precursor (EC 3.4.21.-) (hK7) (Stratum corneum chymotryptic enzyme) (hSCCE).

KLK7_MOUSE
θ value	θ > 10 (rank : 261)	NC score	0.052304 (rank : 353)
Query Neighborhood Hits	118	Target Neighborhood Hits	175	Shared Neighborhood Hits	14
SwissProt Accessions	Q91VE3, Q9R048	Gene names	Klk7, Prss6, Scce
Domain Architecture	No domain graphic available
Description	Kallikrein-7 precursor (EC 3.4.21.-) (Stratum corneum chymotryptic enzyme) (Thymopsin).

KLK9_HUMAN
θ value	θ > 10 (rank : 262)	NC score	0.050457 (rank : 379)
Query Neighborhood Hits	118	Target Neighborhood Hits	176	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UKQ9	Gene names	KLK9
Domain Architecture
Description	Kallikrein-9 precursor (EC 3.4.21.-) (Kallikrein-like protein 3) (KLK- L3).

KLKB1_HUMAN
θ value	θ > 10 (rank : 263)	NC score	0.059001 (rank : 273)
Query Neighborhood Hits	118	Target Neighborhood Hits	183	Shared Neighborhood Hits	14
SwissProt Accessions	P03952	Gene names	KLKB1, KLK3
Domain Architecture
Description	Plasma kallikrein precursor (EC 3.4.21.34) (Plasma prekallikrein) (Kininogenin) (Fletcher factor) [Contains: Plasma kallikrein heavy chain; Plasma kallikrein light chain].

KLKB1_MOUSE
θ value	θ > 10 (rank : 264)	NC score	0.059822 (rank : 256)
Query Neighborhood Hits	118	Target Neighborhood Hits	177	Shared Neighborhood Hits	14
SwissProt Accessions	P26262	Gene names	Klkb1, Klk3, Pk
Domain Architecture
Description	Plasma kallikrein precursor (EC 3.4.21.34) (Plasma prekallikrein) (Kininogenin) (Fletcher factor) [Contains: Plasma kallikrein heavy chain; Plasma kallikrein light chain].

KREM2_HUMAN
θ value	θ > 10 (rank : 265)	NC score	0.264116 (rank : 76)
Query Neighborhood Hits	118	Target Neighborhood Hits	93	Shared Neighborhood Hits	55
SwissProt Accessions	Q8NCW0, Q8N2J4, Q8NCW1, Q96GL8, Q9BTP9	Gene names	KREMEN2, KRM2
Domain Architecture
Description	Kremen protein 2 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 2) (Dickkopf receptor 2).

KREM2_MOUSE
θ value	θ > 10 (rank : 266)	NC score	0.236980 (rank : 79)
Query Neighborhood Hits	118	Target Neighborhood Hits	90	Shared Neighborhood Hits	55
SwissProt Accessions	Q8K1S7	Gene names	Kremen2
Domain Architecture
Description	Kremen protein 2 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 2) (Dickkopf receptor 2).

LDLR_HUMAN
θ value	θ > 10 (rank : 267)	NC score	0.076330 (rank : 173)
Query Neighborhood Hits	118	Target Neighborhood Hits	375	Shared Neighborhood Hits	38
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LDLR_MOUSE
θ value	θ > 10 (rank : 268)	NC score	0.078016 (rank : 164)
Query Neighborhood Hits	118	Target Neighborhood Hits	382	Shared Neighborhood Hits	37
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LRP1B_HUMAN
θ value	θ > 10 (rank : 269)	NC score	0.076220 (rank : 174)
Query Neighborhood Hits	118	Target Neighborhood Hits	602	Shared Neighborhood Hits	45
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LRP1B_MOUSE
θ value	θ > 10 (rank : 270)	NC score	0.076724 (rank : 171)
Query Neighborhood Hits	118	Target Neighborhood Hits	606	Shared Neighborhood Hits	46
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LRP1_HUMAN
θ value	θ > 10 (rank : 271)	NC score	0.074021 (rank : 184)
Query Neighborhood Hits	118	Target Neighborhood Hits	617	Shared Neighborhood Hits	47
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

LRP2_HUMAN
θ value	θ > 10 (rank : 272)	NC score	0.082630 (rank : 146)
Query Neighborhood Hits	118	Target Neighborhood Hits	573	Shared Neighborhood Hits	45
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

LRP4_HUMAN
θ value	θ > 10 (rank : 273)	NC score	0.065823 (rank : 216)
Query Neighborhood Hits	118	Target Neighborhood Hits	355	Shared Neighborhood Hits	38
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

LRP4_MOUSE
θ value	θ > 10 (rank : 274)	NC score	0.066283 (rank : 213)
Query Neighborhood Hits	118	Target Neighborhood Hits	351	Shared Neighborhood Hits	38
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

LRP5_HUMAN
θ value	θ > 10 (rank : 275)	NC score	0.050684 (rank : 376)
Query Neighborhood Hits	118	Target Neighborhood Hits	224	Shared Neighborhood Hits	32
SwissProt Accessions	O75197, Q96TD6, Q9UP66	Gene names	LRP5, LRP7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor.

LRP6_HUMAN
θ value	θ > 10 (rank : 276)	NC score	0.058988 (rank : 274)
Query Neighborhood Hits	118	Target Neighborhood Hits	235	Shared Neighborhood Hits	37
SwissProt Accessions	O75581	Gene names	LRP6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

LRP6_MOUSE
θ value	θ > 10 (rank : 277)	NC score	0.059526 (rank : 263)
Query Neighborhood Hits	118	Target Neighborhood Hits	232	Shared Neighborhood Hits	38
SwissProt Accessions	O88572	Gene names	Lrp6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

LRP8_HUMAN
θ value	θ > 10 (rank : 278)	NC score	0.072060 (rank : 193)
Query Neighborhood Hits	118	Target Neighborhood Hits	346	Shared Neighborhood Hits	37
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

LRP8_MOUSE
θ value	θ > 10 (rank : 279)	NC score	0.074077 (rank : 183)
Query Neighborhood Hits	118	Target Neighborhood Hits	385	Shared Neighborhood Hits	37
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

LTB1L_HUMAN
θ value	θ > 10 (rank : 280)	NC score	0.055425 (rank : 317)
Query Neighborhood Hits	118	Target Neighborhood Hits	553	Shared Neighborhood Hits	35
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1L_MOUSE
θ value	θ > 10 (rank : 281)	NC score	0.055066 (rank : 324)
Query Neighborhood Hits	118	Target Neighborhood Hits	514	Shared Neighborhood Hits	36
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_HUMAN
θ value	θ > 10 (rank : 282)	NC score	0.055567 (rank : 314)
Query Neighborhood Hits	118	Target Neighborhood Hits	502	Shared Neighborhood Hits	35
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_MOUSE
θ value	θ > 10 (rank : 283)	NC score	0.055389 (rank : 318)
Query Neighborhood Hits	118	Target Neighborhood Hits	479	Shared Neighborhood Hits	36
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTBP2_HUMAN
θ value	θ > 10 (rank : 284)	NC score	0.052927 (rank : 346)
Query Neighborhood Hits	118	Target Neighborhood Hits	552	Shared Neighborhood Hits	35
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LTBP2_MOUSE
θ value	θ > 10 (rank : 285)	NC score	0.055513 (rank : 315)
Query Neighborhood Hits	118	Target Neighborhood Hits	617	Shared Neighborhood Hits	39
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LTBP3_HUMAN
θ value	θ > 10 (rank : 286)	NC score	0.053082 (rank : 345)
Query Neighborhood Hits	118	Target Neighborhood Hits	502	Shared Neighborhood Hits	35
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

LTBP3_MOUSE
θ value	θ > 10 (rank : 287)	NC score	0.058738 (rank : 276)
Query Neighborhood Hits	118	Target Neighborhood Hits	475	Shared Neighborhood Hits	33
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

LYAM1_HUMAN
θ value	θ > 10 (rank : 288)	NC score	0.053499 (rank : 343)
Query Neighborhood Hits	118	Target Neighborhood Hits	315	Shared Neighborhood Hits	25
SwissProt Accessions	P14151, P15023	Gene names	SELL, LNHR, LYAM1
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Leukocyte surface antigen Leu-8) (TQ1) (gp90-MEL) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

LYAM1_MOUSE
θ value	θ > 10 (rank : 289)	NC score	0.058245 (rank : 283)
Query Neighborhood Hits	118	Target Neighborhood Hits	332	Shared Neighborhood Hits	29
SwissProt Accessions	P18337	Gene names	Sell, Lnhr, Ly-22
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Lymphocyte antigen 22) (Ly-22) (Lymphocyte surface MEL-14 antigen) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

LYAM2_HUMAN
θ value	θ > 10 (rank : 290)	NC score	0.092889 (rank : 125)
Query Neighborhood Hits	118	Target Neighborhood Hits	394	Shared Neighborhood Hits	34
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

LYAM2_MOUSE
θ value	θ > 10 (rank : 291)	NC score	0.086704 (rank : 134)
Query Neighborhood Hits	118	Target Neighborhood Hits	420	Shared Neighborhood Hits	36
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

LYAM3_HUMAN
θ value	θ > 10 (rank : 292)	NC score	0.080642 (rank : 153)
Query Neighborhood Hits	118	Target Neighborhood Hits	378	Shared Neighborhood Hits	29
SwissProt Accessions	P16109, Q8IVD1	Gene names	SELP, GMRP
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

LYAM3_MOUSE
θ value	θ > 10 (rank : 293)	NC score	0.095664 (rank : 115)
Query Neighborhood Hits	118	Target Neighborhood Hits	390	Shared Neighborhood Hits	36
SwissProt Accessions	Q01102	Gene names	Selp, Grmp
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

MAMC2_HUMAN
θ value	θ > 10 (rank : 294)	NC score	0.078091 (rank : 163)
Query Neighborhood Hits	118	Target Neighborhood Hits	31	Shared Neighborhood Hits	6
SwissProt Accessions	Q7Z304, Q5VW47, Q8WX43, Q96BM4	Gene names	MAMDC2
Domain Architecture
Description	MAM domain-containing protein 2 precursor.

MAMC2_MOUSE
θ value	θ > 10 (rank : 295)	NC score	0.074129 (rank : 182)
Query Neighborhood Hits	118	Target Neighborhood Hits	31	Shared Neighborhood Hits	6
SwissProt Accessions	Q8CG85, Q8BM24	Gene names	Mamdc2
Domain Architecture
Description	MAM domain-containing protein 2 precursor.

MATN1_HUMAN
θ value	θ > 10 (rank : 296)	NC score	0.066123 (rank : 214)
Query Neighborhood Hits	118	Target Neighborhood Hits	191	Shared Neighborhood Hits	23
SwissProt Accessions	P21941	Gene names	MATN1, CMP, CRTM
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

MATN1_MOUSE
θ value	θ > 10 (rank : 297)	NC score	0.063680 (rank : 222)
Query Neighborhood Hits	118	Target Neighborhood Hits	186	Shared Neighborhood Hits	21
SwissProt Accessions	P51942	Gene names	Matn1, Cmp, Crtm
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

MATN2_HUMAN
θ value	θ > 10 (rank : 298)	NC score	0.068321 (rank : 207)
Query Neighborhood Hits	118	Target Neighborhood Hits	365	Shared Neighborhood Hits	31
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

MATN2_MOUSE
θ value	θ > 10 (rank : 299)	NC score	0.071619 (rank : 195)
Query Neighborhood Hits	118	Target Neighborhood Hits	356	Shared Neighborhood Hits	31
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

MATN3_HUMAN
θ value	θ > 10 (rank : 300)	NC score	0.053939 (rank : 338)
Query Neighborhood Hits	118	Target Neighborhood Hits	268	Shared Neighborhood Hits	26
SwissProt Accessions	O15232	Gene names	MATN3
Domain Architecture
Description	Matrilin-3 precursor.

MATN3_MOUSE
θ value	θ > 10 (rank : 301)	NC score	0.052259 (rank : 354)
Query Neighborhood Hits	118	Target Neighborhood Hits	261	Shared Neighborhood Hits	25
SwissProt Accessions	O35701, Q9JHM0	Gene names	Matn3
Domain Architecture
Description	Matrilin-3 precursor.

MATN4_HUMAN
θ value	θ > 10 (rank : 302)	NC score	0.068447 (rank : 206)
Query Neighborhood Hits	118	Target Neighborhood Hits	287	Shared Neighborhood Hits	28
SwissProt Accessions	O95460, Q5QPU2, Q5QPU3, Q5QPU4, Q8N2M5, Q8N2M7, Q9H1F8, Q9H1F9	Gene names	MATN4
Domain Architecture
Description	Matrilin-4 precursor.

MATN4_MOUSE
θ value	θ > 10 (rank : 303)	NC score	0.065832 (rank : 215)
Query Neighborhood Hits	118	Target Neighborhood Hits	277	Shared Neighborhood Hits	27
SwissProt Accessions	O89029, O89030, Q9QWS3	Gene names	Matn4
Domain Architecture
Description	Matrilin-4 precursor (MAT-4).

MCPT6_MOUSE
θ value	θ > 10 (rank : 304)	NC score	0.056898 (rank : 297)
Query Neighborhood Hits	118	Target Neighborhood Hits	175	Shared Neighborhood Hits	14
SwissProt Accessions	P21845, Q61962	Gene names	Mcpt6
Domain Architecture
Description	Mast cell protease 6 precursor (EC 3.4.21.59) (MMCP-6) (Tryptase).

MCP_HUMAN
θ value	θ > 10 (rank : 305)	NC score	0.071212 (rank : 198)
Query Neighborhood Hits	118	Target Neighborhood Hits	82	Shared Neighborhood Hits	15
SwissProt Accessions	P15529, Q15429, Q53GV9, Q5HY94, Q5VWS6, Q5VWS7, Q5VWS8, Q5VWS9, Q5VWT0, Q5VWT1, Q5VWT2, Q6N0A1, Q7Z3R5, Q9NNW2, Q9NNW3, Q9NNW4	Gene names	CD46, MCP
Domain Architecture
Description	Membrane cofactor protein precursor (Trophoblast leukocyte common antigen) (TLX) (CD46 antigen).

MCP_MOUSE
θ value	θ > 10 (rank : 306)	NC score	0.078974 (rank : 161)
Query Neighborhood Hits	118	Target Neighborhood Hits	79	Shared Neighborhood Hits	15
SwissProt Accessions	O88174, Q9R0R9	Gene names	Cd46, Mcp
Domain Architecture	No domain graphic available
Description	Membrane cofactor protein precursor (CD46 antigen).

MEGF6_HUMAN
θ value	θ > 10 (rank : 307)	NC score	0.064202 (rank : 219)
Query Neighborhood Hits	118	Target Neighborhood Hits	671	Shared Neighborhood Hits	31
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

MEP1A_HUMAN
θ value	θ > 10 (rank : 308)	NC score	0.130064 (rank : 98)
Query Neighborhood Hits	118	Target Neighborhood Hits	162	Shared Neighborhood Hits	18
SwissProt Accessions	Q16819	Gene names	MEP1A
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit alpha) (PABA peptide hydrolase) (PPH alpha).

MEP1A_MOUSE
θ value	θ > 10 (rank : 309)	NC score	0.124283 (rank : 100)
Query Neighborhood Hits	118	Target Neighborhood Hits	166	Shared Neighborhood Hits	17
SwissProt Accessions	P28825	Gene names	Mep1a
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (MEP-1).

MEP1B_HUMAN
θ value	θ > 10 (rank : 310)	NC score	0.120729 (rank : 102)
Query Neighborhood Hits	118	Target Neighborhood Hits	98	Shared Neighborhood Hits	11
SwissProt Accessions	Q16820, Q670J1	Gene names	MEP1B
Domain Architecture
Description	Meprin A subunit beta precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit beta) (PABA peptide hydrolase) (PPH beta).

MEP1B_MOUSE
θ value	θ > 10 (rank : 311)	NC score	0.136753 (rank : 94)
Query Neighborhood Hits	118	Target Neighborhood Hits	127	Shared Neighborhood Hits	14
SwissProt Accessions	Q61847	Gene names	Mep1b, Mep-1b
Domain Architecture
Description	Meprin A subunit beta precursor (EC 3.4.24.18) (Endopeptidase-2).

NETR_HUMAN
θ value	θ > 10 (rank : 312)	NC score	0.074152 (rank : 181)
Query Neighborhood Hits	118	Target Neighborhood Hits	218	Shared Neighborhood Hits	18
SwissProt Accessions	P56730, Q9UP16	Gene names	PRSS12
Domain Architecture
Description	Neurotrypsin precursor (EC 3.4.21.-) (Motopsin) (Leydin).

NETR_MOUSE
θ value	θ > 10 (rank : 313)	NC score	0.072769 (rank : 189)
Query Neighborhood Hits	118	Target Neighborhood Hits	216	Shared Neighborhood Hits	18
SwissProt Accessions	O08762	Gene names	Prss12, Bssp3
Domain Architecture
Description	Neurotrypsin precursor (EC 3.4.21.-) (Motopsin) (Brain-specific serine protease 3) (BSSP-3).

NID2_MOUSE
θ value	θ > 10 (rank : 314)	NC score	0.051472 (rank : 368)
Query Neighborhood Hits	118	Target Neighborhood Hits	338	Shared Neighborhood Hits	33
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

NOTC1_HUMAN
θ value	θ > 10 (rank : 315)	NC score	0.055937 (rank : 309)
Query Neighborhood Hits	118	Target Neighborhood Hits	906	Shared Neighborhood Hits	39
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC1_MOUSE
θ value	θ > 10 (rank : 316)	NC score	0.057522 (rank : 291)
Query Neighborhood Hits	118	Target Neighborhood Hits	916	Shared Neighborhood Hits	40
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC2_HUMAN
θ value	θ > 10 (rank : 317)	NC score	0.055571 (rank : 313)
Query Neighborhood Hits	118	Target Neighborhood Hits	1113	Shared Neighborhood Hits	42
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC2_MOUSE
θ value	θ > 10 (rank : 318)	NC score	0.057161 (rank : 294)
Query Neighborhood Hits	118	Target Neighborhood Hits	1069	Shared Neighborhood Hits	44
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC3_HUMAN
θ value	θ > 10 (rank : 319)	NC score	0.052782 (rank : 349)
Query Neighborhood Hits	118	Target Neighborhood Hits	1062	Shared Neighborhood Hits	39
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC3_MOUSE
θ value	θ > 10 (rank : 320)	NC score	0.053673 (rank : 341)
Query Neighborhood Hits	118	Target Neighborhood Hits	975	Shared Neighborhood Hits	44
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC4_MOUSE
θ value	θ > 10 (rank : 321)	NC score	0.051420 (rank : 369)
Query Neighborhood Hits	118	Target Neighborhood Hits	872	Shared Neighborhood Hits	38
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

NRPN_HUMAN
θ value	θ > 10 (rank : 322)	NC score	0.053680 (rank : 340)
Query Neighborhood Hits	118	Target Neighborhood Hits	182	Shared Neighborhood Hits	14
SwissProt Accessions	O60259, Q9HCB3, Q9UIL9, Q9UQ47	Gene names	KLK8, NRPN, PRSS19, TADG14
Domain Architecture
Description	Neuropsin precursor (EC 3.4.21.-) (NP) (Kallikrein-8) (Ovasin) (Serine protease TADG-14) (Tumor-associated differentially expressed gene 14 protein).

NRPN_MOUSE
θ value	θ > 10 (rank : 323)	NC score	0.052058 (rank : 359)
Query Neighborhood Hits	118	Target Neighborhood Hits	186	Shared Neighborhood Hits	14
SwissProt Accessions	Q61955	Gene names	Klk8, Nrpn, Prss19
Domain Architecture
Description	Neuropsin precursor (EC 3.4.21.-) (NP) (Kallikrein-8).

NRX1A_HUMAN
θ value	θ > 10 (rank : 324)	NC score	0.096706 (rank : 114)
Query Neighborhood Hits	118	Target Neighborhood Hits	170	Shared Neighborhood Hits	17
SwissProt Accessions	Q9ULB1, O60323, Q53TJ9, Q53TQ1, Q9C079, Q9C080, Q9C081, Q9H3M2, Q9UDM6	Gene names	NRXN1, KIAA0578
Domain Architecture
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

NRX1A_MOUSE
θ value	θ > 10 (rank : 325)	NC score	0.095621 (rank : 116)
Query Neighborhood Hits	118	Target Neighborhood Hits	164	Shared Neighborhood Hits	17
SwissProt Accessions	Q9CS84, O88722, Q80Y87, Q8CHE6	Gene names	Nrxn1, Kiaa0578
Domain Architecture	No domain graphic available
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

NRX2A_HUMAN
θ value	θ > 10 (rank : 326)	NC score	0.081366 (rank : 150)
Query Neighborhood Hits	118	Target Neighborhood Hits	614	Shared Neighborhood Hits	19
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

NRX3A_HUMAN
θ value	θ > 10 (rank : 327)	NC score	0.092352 (rank : 128)
Query Neighborhood Hits	118	Target Neighborhood Hits	164	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y4C0, O95378, Q9NS47, Q9P1V3, Q9P1V6, Q9UIE2, Q9UIE3, Q9ULA5, Q9Y486	Gene names	NRXN3, KIAA0743
Domain Architecture
Description	Neurexin-3-alpha precursor (Neurexin III-alpha).

PAPPA_MOUSE
θ value	θ > 10 (rank : 328)	NC score	0.052095 (rank : 358)
Query Neighborhood Hits	118	Target Neighborhood Hits	153	Shared Neighborhood Hits	13
SwissProt Accessions	Q8R4K8, Q80VW3, Q80YY1, Q8K423, Q8R4K7, Q9ES06, Q9JK57	Gene names	Pappa
Domain Architecture	No domain graphic available
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

PDGFD_MOUSE
θ value	θ > 10 (rank : 329)	NC score	0.451547 (rank : 40)
Query Neighborhood Hits	118	Target Neighborhood Hits	72	Shared Neighborhood Hits	57
SwissProt Accessions	Q925I7, Q3URF6, Q8K2L3, Q9D1L8	Gene names	Pdgfd, Scdgfb
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor chain precursor (PDGF D) (Spinal cord- derived growth factor B) (SCDGF-B).

PGBM_HUMAN
θ value	θ > 10 (rank : 330)	NC score	0.054140 (rank : 336)
Query Neighborhood Hits	118	Target Neighborhood Hits	1113	Shared Neighborhood Hits	34
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

PGBM_MOUSE
θ value	θ > 10 (rank : 331)	NC score	0.058223 (rank : 285)
Query Neighborhood Hits	118	Target Neighborhood Hits	1073	Shared Neighborhood Hits	37
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

PLMN_HUMAN
θ value	θ > 10 (rank : 332)	NC score	0.057075 (rank : 295)
Query Neighborhood Hits	118	Target Neighborhood Hits	204	Shared Neighborhood Hits	16
SwissProt Accessions	P00747, Q15146, Q6PA00	Gene names	PLG
Domain Architecture
Description	Plasminogen precursor (EC 3.4.21.7) [Contains: Plasmin heavy chain A; Activation peptide; Angiostatin; Plasmin heavy chain A, short form; Plasmin light chain B].

PLMN_MOUSE
θ value	θ > 10 (rank : 333)	NC score	0.058552 (rank : 279)
Query Neighborhood Hits	118	Target Neighborhood Hits	208	Shared Neighborhood Hits	16
SwissProt Accessions	P20918, Q8CIS2, Q91WJ5	Gene names	Plg
Domain Architecture
Description	Plasminogen precursor (EC 3.4.21.7) [Contains: Plasmin heavy chain A; Activation peptide; Angiostatin; Plasmin heavy chain A, short form; Plasmin light chain B].

POLS2_HUMAN
θ value	θ > 10 (rank : 334)	NC score	0.057744 (rank : 288)
Query Neighborhood Hits	118	Target Neighborhood Hits	192	Shared Neighborhood Hits	14
SwissProt Accessions	Q5K4E3, Q8NBY4	Gene names	PRSS36
Domain Architecture	No domain graphic available
Description	Polyserase-2 precursor (EC 3.4.21.-) (Polyserine protease 2) (Protease serine 36).

POLS2_MOUSE
θ value	θ > 10 (rank : 335)	NC score	0.057930 (rank : 287)
Query Neighborhood Hits	118	Target Neighborhood Hits	188	Shared Neighborhood Hits	14
SwissProt Accessions	Q5K2P8	Gene names	Prss36
Domain Architecture	No domain graphic available
Description	Polyserase-2 precursor (EC 3.4.21.-) (Polyserine protease 2) (Protease serine 36).

PROC_HUMAN
θ value	θ > 10 (rank : 336)	NC score	0.079040 (rank : 160)
Query Neighborhood Hits	118	Target Neighborhood Hits	406	Shared Neighborhood Hits	31
SwissProt Accessions	P04070, Q15189, Q15190, Q16001	Gene names	PROC
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

PROC_MOUSE
θ value	θ > 10 (rank : 337)	NC score	0.077757 (rank : 166)
Query Neighborhood Hits	118	Target Neighborhood Hits	426	Shared Neighborhood Hits	31
SwissProt Accessions	P33587, O35498, Q91WN8, Q99PC6	Gene names	Proc
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

PROS_HUMAN
θ value	θ > 10 (rank : 338)	NC score	0.083253 (rank : 145)
Query Neighborhood Hits	118	Target Neighborhood Hits	340	Shared Neighborhood Hits	35
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

PROS_MOUSE
θ value	θ > 10 (rank : 339)	NC score	0.077547 (rank : 168)
Query Neighborhood Hits	118	Target Neighborhood Hits	330	Shared Neighborhood Hits	35
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

PROZ_HUMAN
θ value	θ > 10 (rank : 340)	NC score	0.093051 (rank : 123)
Query Neighborhood Hits	118	Target Neighborhood Hits	422	Shared Neighborhood Hits	36
SwissProt Accessions	P22891, Q15213	Gene names	PROZ
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

PROZ_MOUSE
θ value	θ > 10 (rank : 341)	NC score	0.090669 (rank : 130)
Query Neighborhood Hits	118	Target Neighborhood Hits	410	Shared Neighborhood Hits	35
SwissProt Accessions	Q9CQW3	Gene names	Proz
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

PRS27_HUMAN
θ value	θ > 10 (rank : 342)	NC score	0.059637 (rank : 260)
Query Neighborhood Hits	118	Target Neighborhood Hits	177	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BQR3	Gene names	PRSS27, MPN
Domain Architecture
Description	Protease serine 27 precursor (EC 3.4.21.-) (Marapsin) (Pancreasin) (Channel-activating protease 2) (CAPH2).

PRS27_MOUSE
θ value	θ > 10 (rank : 343)	NC score	0.059296 (rank : 267)
Query Neighborhood Hits	118	Target Neighborhood Hits	175	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BJR6	Gene names	Prss27, Mpn
Domain Architecture	No domain graphic available
Description	Protease serine 27 precursor (EC 3.4.21.-) (Marapsin) (Pancreasin).

PRSS8_HUMAN
θ value	θ > 10 (rank : 344)	NC score	0.059679 (rank : 259)
Query Neighborhood Hits	118	Target Neighborhood Hits	177	Shared Neighborhood Hits	14
SwissProt Accessions	Q16651, Q9UCA3	Gene names	PRSS8
Domain Architecture
Description	Prostasin precursor (EC 3.4.21.-) [Contains: Prostasin light chain; Prostasin heavy chain].

PRSS8_MOUSE
θ value	θ > 10 (rank : 345)	NC score	0.059567 (rank : 261)
Query Neighborhood Hits	118	Target Neighborhood Hits	177	Shared Neighborhood Hits	14
SwissProt Accessions	Q9ESD1	Gene names	Prss8, Cap1
Domain Architecture
Description	Prostasin precursor (EC 3.4.21.-) (Channel-activating protease 1) [Contains: Prostasin light chain; Prostasin heavy chain].

SHBG_HUMAN
θ value	θ > 10 (rank : 346)	NC score	0.055083 (rank : 323)
Query Neighborhood Hits	118	Target Neighborhood Hits	45	Shared Neighborhood Hits	7
SwissProt Accessions	P04278, P14689, Q16616	Gene names	SHBG
Domain Architecture
Description	Sex hormone-binding globulin precursor (SHBG) (Sex steroid-binding protein) (SBP) (Testis-specific androgen-binding protein) (ABP) (Testosterone-estrogen-binding globulin) (Testosterone-estradiol- binding globulin) (TeBG).

STAB1_HUMAN
θ value	θ > 10 (rank : 347)	NC score	0.054368 (rank : 333)
Query Neighborhood Hits	118	Target Neighborhood Hits	546	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

STAB1_MOUSE
θ value	θ > 10 (rank : 348)	NC score	0.053950 (rank : 337)
Query Neighborhood Hits	118	Target Neighborhood Hits	566	Shared Neighborhood Hits	24
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

SUSD1_HUMAN
θ value	θ > 10 (rank : 349)	NC score	0.077837 (rank : 165)
Query Neighborhood Hits	118	Target Neighborhood Hits	285	Shared Neighborhood Hits	34
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

SUSD2_HUMAN
θ value	θ > 10 (rank : 350)	NC score	0.050523 (rank : 378)
Query Neighborhood Hits	118	Target Neighborhood Hits	99	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UGT4, Q9H5Y6	Gene names	SUSD2
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 2 precursor.

SUSD4_HUMAN
θ value	θ > 10 (rank : 351)	NC score	0.060320 (rank : 250)
Query Neighborhood Hits	118	Target Neighborhood Hits	88	Shared Neighborhood Hits	11
SwissProt Accessions	Q5VX71, Q6UX62, Q9BSR0, Q9NWG0	Gene names	SUSD4
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 4 precursor.

SUSD4_MOUSE
θ value	θ > 10 (rank : 352)	NC score	0.056168 (rank : 307)
Query Neighborhood Hits	118	Target Neighborhood Hits	122	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BH32, Q8VC43	Gene names	Susd4
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 4 precursor.

TEST_HUMAN
θ value	θ > 10 (rank : 353)	NC score	0.059819 (rank : 257)
Query Neighborhood Hits	118	Target Neighborhood Hits	172	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y6M0, Q9NS34, Q9P2V6	Gene names	PRSS21, ESP1, TEST1
Domain Architecture
Description	Testisin precursor (EC 3.4.21.-) (Eosinophil serine protease 1) (ESP- 1).

TEST_MOUSE
θ value	θ > 10 (rank : 354)	NC score	0.061370 (rank : 243)
Query Neighborhood Hits	118	Target Neighborhood Hits	174	Shared Neighborhood Hits	14
SwissProt Accessions	Q9JHJ7, Q9DA14	Gene names	Prss21
Domain Architecture
Description	Testisin precursor (EC 3.4.21.-) (Tryptase 4).

THRB_HUMAN
θ value	θ > 10 (rank : 355)	NC score	0.068849 (rank : 204)
Query Neighborhood Hits	118	Target Neighborhood Hits	196	Shared Neighborhood Hits	16
SwissProt Accessions	P00734	Gene names	F2
Domain Architecture
Description	Prothrombin precursor (EC 3.4.21.5) (Coagulation factor II) [Contains: Activation peptide fragment 1; Activation peptide fragment 2; Thrombin light chain; Thrombin heavy chain].

THRB_MOUSE
θ value	θ > 10 (rank : 356)	NC score	0.068032 (rank : 209)
Query Neighborhood Hits	118	Target Neighborhood Hits	195	Shared Neighborhood Hits	16
SwissProt Accessions	P19221	Gene names	F2, Cf2
Domain Architecture
Description	Prothrombin precursor (EC 3.4.21.5) (Coagulation factor II) [Contains: Activation peptide fragment 1; Activation peptide fragment 2; Thrombin light chain; Thrombin heavy chain].

TM11D_HUMAN
θ value	θ > 10 (rank : 357)	NC score	0.063728 (rank : 220)
Query Neighborhood Hits	118	Target Neighborhood Hits	176	Shared Neighborhood Hits	14
SwissProt Accessions	O60235	Gene names	TMPRSS11D, HAT
Domain Architecture
Description	Transmembrane protease, serine 11D precursor (EC 3.4.21.-) (Airway trypsin-like protease) [Contains: Transmembrane protease, serine 11D non-catalytic chain; Transmembrane protease, serine 11D catalytic chain].

TM11D_MOUSE
θ value	θ > 10 (rank : 358)	NC score	0.062767 (rank : 228)
Query Neighborhood Hits	118	Target Neighborhood Hits	179	Shared Neighborhood Hits	14
SwissProt Accessions	Q8VHK8, Q7TNX3, Q8VDV1	Gene names	Tmprss11d, Mat
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 11D precursor (EC 3.4.21.-) (Airway trypsin-like protease) (AT) (Adrenal secretory serine protease) (AsP) [Contains: Transmembrane protease, serine 11D non-catalytic chain; Transmembrane protease, serine 11D catalytic chain].

TM11E_HUMAN
θ value	θ > 10 (rank : 359)	NC score	0.062380 (rank : 233)
Query Neighborhood Hits	118	Target Neighborhood Hits	181	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UL52, Q6UW31	Gene names	TMPRSS11E, DESC1
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 11E precursor (EC 3.4.21.-) (Serine protease DESC1) [Contains: Transmembrane protease, serine 11E non- catalytic chain; Transmembrane protease, serine 11E catalytic chain].

TM11E_MOUSE
θ value	θ > 10 (rank : 360)	NC score	0.062460 (rank : 231)
Query Neighborhood Hits	118	Target Neighborhood Hits	176	Shared Neighborhood Hits	14
SwissProt Accessions	Q5S248, Q8BM10	Gene names	Tmprss11e, Desc1
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 11E precursor (EC 3.4.21.-) (Serine protease DESC1) [Contains: Transmembrane protease, serine 11E non- catalytic chain; Transmembrane protease, serine 11E catalytic chain].

TMPS2_HUMAN
θ value	θ > 10 (rank : 361)	NC score	0.068636 (rank : 205)
Query Neighborhood Hits	118	Target Neighborhood Hits	252	Shared Neighborhood Hits	27
SwissProt Accessions	O15393, Q9BXX1	Gene names	TMPRSS2, PRSS10
Domain Architecture
Description	Transmembrane protease, serine 2 precursor (EC 3.4.21.-) [Contains: Transmembrane protease, serine 2 non-catalytic chain; Transmembrane protease, serine 2 catalytic chain].

TMPS2_MOUSE
θ value	θ > 10 (rank : 362)	NC score	0.067539 (rank : 211)
Query Neighborhood Hits	118	Target Neighborhood Hits	243	Shared Neighborhood Hits	26
SwissProt Accessions	Q9JIQ8, Q9JKC4, Q9QY82	Gene names	Tmprss2
Domain Architecture
Description	Transmembrane protease, serine 2 (EC 3.4.21.-) (Epitheliasin) (Plasmic transmembrane protein X) [Contains: Transmembrane protease, serine 2 non-catalytic chain; Transmembrane protease, serine 2 catalytic chain].

TMPS3_HUMAN
θ value	θ > 10 (rank : 363)	NC score	0.063137 (rank : 225)
Query Neighborhood Hits	118	Target Neighborhood Hits	245	Shared Neighborhood Hits	24
SwissProt Accessions	P57727, Q6ZMC3	Gene names	TMPRSS3, ECHOS1, TADG12
Domain Architecture
Description	Transmembrane protease, serine 3 (EC 3.4.21.-) (Serine protease TADG- 12) (Tumor-associated differentially-expressed gene 12 protein).

TMPS3_MOUSE
θ value	θ > 10 (rank : 364)	NC score	0.061430 (rank : 242)
Query Neighborhood Hits	118	Target Neighborhood Hits	239	Shared Neighborhood Hits	21
SwissProt Accessions	Q8K1T0, Q8VDE0	Gene names	Tmprss3
Domain Architecture
Description	Transmembrane protease, serine 3 (EC 3.4.21.-).

TMPS4_HUMAN
θ value	θ > 10 (rank : 365)	NC score	0.060314 (rank : 252)
Query Neighborhood Hits	118	Target Neighborhood Hits	203	Shared Neighborhood Hits	15
SwissProt Accessions	Q9NRS4, Q5XKQ6, Q6UX37, Q9NZA5	Gene names	TMPRSS4, TMPRSS3
Domain Architecture
Description	Transmembrane protease, serine 4 (EC 3.4.21.-) (Membrane-type serine protease 2) (MT-SP2).

TMPS4_MOUSE
θ value	θ > 10 (rank : 366)	NC score	0.061775 (rank : 239)
Query Neighborhood Hits	118	Target Neighborhood Hits	210	Shared Neighborhood Hits	21
SwissProt Accessions	Q8VCA5	Gene names	Tmprss4, Cap2
Domain Architecture
Description	Transmembrane protease, serine 4 (EC 3.4.21.-) (Channel-activating protease 2) (mCAP2).

TMPS5_HUMAN
θ value	θ > 10 (rank : 367)	NC score	0.057418 (rank : 293)
Query Neighborhood Hits	118	Target Neighborhood Hits	181	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H3S3	Gene names	TMPRSS5
Domain Architecture
Description	Transmembrane protease, serine 5 (EC 3.4.21.-) (Spinesin).

TMPS5_MOUSE
θ value	θ > 10 (rank : 368)	NC score	0.057457 (rank : 292)
Query Neighborhood Hits	118	Target Neighborhood Hits	185	Shared Neighborhood Hits	15
SwissProt Accessions	Q9ER04, Q9ER02, Q9ER03	Gene names	Tmprss5
Domain Architecture
Description	Transmembrane protease, serine 5 (EC 3.4.21.-) (Spinesin).

TMPS6_HUMAN
θ value	θ > 10 (rank : 369)	NC score	0.096727 (rank : 113)
Query Neighborhood Hits	118	Target Neighborhood Hits	338	Shared Neighborhood Hits	45
SwissProt Accessions	Q8IU80, Q5TI06, Q6UXD8, Q8IUE2, Q8IXV8	Gene names	TMPRSS6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

TMPS6_MOUSE
θ value	θ > 10 (rank : 370)	NC score	0.097974 (rank : 112)
Query Neighborhood Hits	118	Target Neighborhood Hits	341	Shared Neighborhood Hits	49
SwissProt Accessions	Q9DBI0, Q6PF94	Gene names	Tmprss6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

TMPS7_HUMAN
θ value	θ > 10 (rank : 371)	NC score	0.111053 (rank : 109)
Query Neighborhood Hits	118	Target Neighborhood Hits	275	Shared Neighborhood Hits	53
SwissProt Accessions	Q7RTY8	Gene names	TMPRSS7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

TMPS7_MOUSE
θ value	θ > 10 (rank : 372)	NC score	0.105639 (rank : 111)
Query Neighborhood Hits	118	Target Neighborhood Hits	275	Shared Neighborhood Hits	52
SwissProt Accessions	Q8BIK6	Gene names	Tmprss7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

TMPS9_HUMAN
θ value	θ > 10 (rank : 373)	NC score	0.064569 (rank : 217)
Query Neighborhood Hits	118	Target Neighborhood Hits	276	Shared Neighborhood Hits	25
SwissProt Accessions	Q7Z410, Q6ZND6, Q7Z411	Gene names	TMPRSS9
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 9 (EC 3.4.21.-) (Polyserase-1) (Polyserase-I) (Polyserine protease 1) [Contains: Serase-1; Serase-2; Serase-3].

TMPS9_MOUSE
θ value	θ > 10 (rank : 374)	NC score	0.062427 (rank : 232)
Query Neighborhood Hits	118	Target Neighborhood Hits	296	Shared Neighborhood Hits	21
SwissProt Accessions	P69525	Gene names	Tmprss9
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 9 (EC 3.4.21.-) (Polyserase-1) (Polyserine protease 1) (Polyserase-I) [Contains: Serase-1; Serase-2; Serase-3].

TMPSD_HUMAN
θ value	θ > 10 (rank : 375)	NC score	0.059137 (rank : 270)
Query Neighborhood Hits	118	Target Neighborhood Hits	333	Shared Neighborhood Hits	17
SwissProt Accessions	Q9BYE2, Q86YM4, Q96JY8, Q9BYE1	Gene names	TMPRSS13, MSP, TMPRSS11
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).

TMPSD_MOUSE
θ value	θ > 10 (rank : 376)	NC score	0.060811 (rank : 247)
Query Neighborhood Hits	118	Target Neighborhood Hits	334	Shared Neighborhood Hits	16
SwissProt Accessions	Q5U405, Q8CFE0, Q91VQ8	Gene names	Tmprss13, Msp
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).

TMSP8_MOUSE
θ value	θ > 10 (rank : 377)	NC score	0.062936 (rank : 227)
Query Neighborhood Hits	118	Target Neighborhood Hits	176	Shared Neighborhood Hits	14
SwissProt Accessions	Q9QYZ9, Q91XC4	Gene names	Tmprss8, Disp
Domain Architecture
Description	Transmembrane serine protease 8 precursor (EC 3.4.21.-) (Distal intestinal serine protease).

TPA_HUMAN
θ value	θ > 10 (rank : 378)	NC score	0.071610 (rank : 196)
Query Neighborhood Hits	118	Target Neighborhood Hits	324	Shared Neighborhood Hits	24
SwissProt Accessions	P00750, Q15103, Q7Z7N2, Q86YK8, Q9BU99	Gene names	PLAT
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) (Alteplase) (Reteplase) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

TPA_MOUSE
θ value	θ > 10 (rank : 379)	NC score	0.069110 (rank : 202)
Query Neighborhood Hits	118	Target Neighborhood Hits	335	Shared Neighborhood Hits	24
SwissProt Accessions	P11214, Q91VP2	Gene names	Plat
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

TRY1_HUMAN
θ value	θ > 10 (rank : 380)	NC score	0.054691 (rank : 331)
Query Neighborhood Hits	118	Target Neighborhood Hits	176	Shared Neighborhood Hits	14
SwissProt Accessions	P07477, Q92955, Q9HAN4, Q9HAN5, Q9HAN6, Q9HAN7	Gene names	PRSS1, TRP1, TRY1, TRYP1
Domain Architecture
Description	Trypsin-1 precursor (EC 3.4.21.4) (Trypsin I) (Cationic trypsinogen).

TRY2_HUMAN
θ value	θ > 10 (rank : 381)	NC score	0.056162 (rank : 308)
Query Neighborhood Hits	118	Target Neighborhood Hits	175	Shared Neighborhood Hits	14
SwissProt Accessions	P07478	Gene names	PRSS2, TRY2, TRYP2
Domain Architecture
Description	Trypsin-2 precursor (EC 3.4.21.4) (Trypsin II) (Anionic trypsinogen).

TRY2_MOUSE
θ value	θ > 10 (rank : 382)	NC score	0.055012 (rank : 325)
Query Neighborhood Hits	118	Target Neighborhood Hits	174	Shared Neighborhood Hits	14
SwissProt Accessions	P07146	Gene names	Prss2, Try2
Domain Architecture
Description	Anionic trypsin-2 precursor (EC 3.4.21.4) (Anionic trypsin II) (Pretrypsinogen II).

TRY3_HUMAN
θ value	θ > 10 (rank : 383)	NC score	0.054236 (rank : 335)
Query Neighborhood Hits	118	Target Neighborhood Hits	178	Shared Neighborhood Hits	14
SwissProt Accessions	P35030, P15951, Q15665, Q9UQV3	Gene names	PRSS3, PRSS4, TRY3, TRY4
Domain Architecture
Description	Trypsin-3 precursor (EC 3.4.21.4) (Trypsin III) (Brain trypsinogen) (Mesotrypsinogen) (Trypsin IV).

TRYA1_HUMAN
θ value	θ > 10 (rank : 384)	NC score	0.055439 (rank : 316)
Query Neighborhood Hits	118	Target Neighborhood Hits	177	Shared Neighborhood Hits	14
SwissProt Accessions	P15157, Q9H2Y5, Q9UQI1	Gene names	TPSAB1, TPS1
Domain Architecture
Description	Tryptase alpha-1 precursor (EC 3.4.21.59) (Tryptase-1).

TRYB1_HUMAN
θ value	θ > 10 (rank : 385)	NC score	0.056629 (rank : 300)
Query Neighborhood Hits	118	Target Neighborhood Hits	175	Shared Neighborhood Hits	14
SwissProt Accessions	Q15661, Q15663, Q9H2Y4	Gene names	TPSAB1, TPSB1
Domain Architecture
Description	Tryptase beta-1 precursor (EC 3.4.21.59) (Tryptase-1) (Tryptase I).

TRYB1_MOUSE
θ value	θ > 10 (rank : 386)	NC score	0.057947 (rank : 286)
Query Neighborhood Hits	118	Target Neighborhood Hits	175	Shared Neighborhood Hits	14
SwissProt Accessions	Q02844	Gene names	Tpsab1, Mcpt7
Domain Architecture
Description	Tryptase precursor (EC 3.4.21.59) (Mast cell protease 7) (MMCP-7) (Tryptase alpha/beta-1).

TRYB2_HUMAN
θ value	θ > 10 (rank : 387)	NC score	0.056629 (rank : 301)
Query Neighborhood Hits	118	Target Neighborhood Hits	175	Shared Neighborhood Hits	14
SwissProt Accessions	P20231, O95827, Q15664, Q9UQI6, Q9UQI7	Gene names	TPSB2, TPS2
Domain Architecture
Description	Tryptase beta-2 precursor (EC 3.4.21.59) (Tryptase-2) (Tryptase II).

TRYD_HUMAN
θ value	θ > 10 (rank : 388)	NC score	0.054859 (rank : 328)
Query Neighborhood Hits	118	Target Neighborhood Hits	175	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BZJ3, O95824, Q8TDI6, Q96L36, Q96RZ5, Q9H2Y6, Q9UQI8	Gene names	TPSD1
Domain Architecture
Description	Tryptase delta precursor (EC 3.4.21.59) (Delta tryptase) (Mast cell mMCP-7-like) (Tryptase-3) (HmMCP-3-like tryptase III).

TRYG1_HUMAN
θ value	θ > 10 (rank : 389)	NC score	0.061522 (rank : 241)
Query Neighborhood Hits	118	Target Neighborhood Hits	179	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NRR2, Q96RZ8, Q9C015, Q9NRQ8, Q9UBB2	Gene names	TPSG1, TMT
Domain Architecture
Description	Tryptase gamma precursor (EC 3.4.21.-) (Transmembrane tryptase) [Contains: Tryptase gamma light chain; Tryptase gamma heavy chain].

TRYG1_MOUSE
θ value	θ > 10 (rank : 390)	NC score	0.060149 (rank : 254)
Query Neighborhood Hits	118	Target Neighborhood Hits	181	Shared Neighborhood Hits	14
SwissProt Accessions	Q9QUL7	Gene names	Tpsg1, Tmt
Domain Architecture
Description	Tryptase gamma precursor (EC 3.4.21.-) (Transmembrane tryptase) [Contains: Tryptase gamma light chain; Tryptase gamma heavy chain].

UROK_HUMAN
θ value	θ > 10 (rank : 391)	NC score	0.057735 (rank : 289)
Query Neighborhood Hits	118	Target Neighborhood Hits	272	Shared Neighborhood Hits	21
SwissProt Accessions	P00749, Q15844, Q16618, Q969W6	Gene names	PLAU
Domain Architecture
Description	Urokinase-type plasminogen activator precursor (EC 3.4.21.73) (uPA) (U-plasminogen activator) [Contains: Urokinase-type plasminogen activator long chain A; Urokinase-type plasminogen activator short chain A; Urokinase-type plasminogen activator chain B].

UROK_MOUSE
θ value	θ > 10 (rank : 392)	NC score	0.056760 (rank : 299)
Query Neighborhood Hits	118	Target Neighborhood Hits	273	Shared Neighborhood Hits	21
SwissProt Accessions	P06869	Gene names	Plau
Domain Architecture
Description	Urokinase-type plasminogen activator precursor (EC 3.4.21.73) (uPA) (U-plasminogen activator) [Contains: Urokinase-type plasminogen activator long chain A; Urokinase-type plasminogen activator short chain A; Urokinase-type plasminogen activator chain B].

UROL1_MOUSE
θ value	θ > 10 (rank : 393)	NC score	0.062591 (rank : 230)
Query Neighborhood Hits	118	Target Neighborhood Hits	235	Shared Neighborhood Hits	19
SwissProt Accessions	Q5DID3, Q5DID1, Q5DID2	Gene names	Umodl1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

UROM_HUMAN
θ value	θ > 10 (rank : 394)	NC score	0.056471 (rank : 302)
Query Neighborhood Hits	118	Target Neighborhood Hits	284	Shared Neighborhood Hits	24
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

UROM_MOUSE
θ value	θ > 10 (rank : 395)	NC score	0.055752 (rank : 311)
Query Neighborhood Hits	118	Target Neighborhood Hits	276	Shared Neighborhood Hits	19
SwissProt Accessions	Q91X17, Q3TN64, Q3TP60, Q62285	Gene names	Umod
Domain Architecture	No domain graphic available
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

VLDLR_HUMAN
θ value	θ > 10 (rank : 396)	NC score	0.070029 (rank : 199)
Query Neighborhood Hits	118	Target Neighborhood Hits	383	Shared Neighborhood Hits	38
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

VLDLR_MOUSE
θ value	θ > 10 (rank : 397)	NC score	0.069013 (rank : 203)
Query Neighborhood Hits	118	Target Neighborhood Hits	360	Shared Neighborhood Hits	39
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

ZAN_HUMAN
θ value	θ > 10 (rank : 398)	NC score	0.059069 (rank : 271)
Query Neighborhood Hits	118	Target Neighborhood Hits	679	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

ZAN_MOUSE
θ value	θ > 10 (rank : 399)	NC score	0.064400 (rank : 218)
Query Neighborhood Hits	118	Target Neighborhood Hits	808	Shared Neighborhood Hits	39
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

ZP2_HUMAN
θ value	θ > 10 (rank : 400)	NC score	0.050860 (rank : 375)
Query Neighborhood Hits	118	Target Neighborhood Hits	26	Shared Neighborhood Hits	4
SwissProt Accessions	Q05996	Gene names	ZP2, ZPA
Domain Architecture
Description	Zona pellucida sperm-binding protein 2 precursor (Zona pellucida glycoprotein ZP2) (Zona pellucida protein A).

ZP3R_MOUSE
θ value	θ > 10 (rank : 401)	NC score	0.079961 (rank : 156)
Query Neighborhood Hits	118	Target Neighborhood Hits	81	Shared Neighborhood Hits	15
SwissProt Accessions	Q60736	Gene names	Zp3r, Sp56
Domain Architecture
Description	Zona pellucida sperm-binding protein 3 receptor precursor (Sperm fertilization protein 56) (sp56).

Hits sorted by NC score

DCBD2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	118	Target Neighborhood Hits	118	Shared Neighborhood Hits	118
SwissProt Accessions	Q96PD2, Q8N6M4, Q8TDX2	Gene names	DCBLD2, CLCP1, ESDN
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein) (CUB, LCCL and coagulation factor V/VIII-homology domains protein 1).

DCBD2_MOUSE
NC score	0.995624 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	118	Target Neighborhood Hits	113	Shared Neighborhood Hits	101
SwissProt Accessions	Q91ZV3, Q8BKI4	Gene names	Dcbld2, Esdn
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein).

DCBD1_HUMAN
NC score	0.947228 (rank : 3)	θ value	6.7005e-96 (rank : 3)
Query Neighborhood Hits	118	Target Neighborhood Hits	110	Shared Neighborhood Hits	89
SwissProt Accessions	Q8N8Z6, Q5H992, Q8IYK5, Q8N7L9, Q96NH2	Gene names	DCBLD1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

NRP2_MOUSE
NC score	0.835598 (rank : 4)	θ value	5.40856e-29 (rank : 9)
Query Neighborhood Hits	118	Target Neighborhood Hits	113	Shared Neighborhood Hits	87
SwissProt Accessions	O35375, O35373, O35374, O35376, O35377, O35378	Gene names	Nrp2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

NRP2_HUMAN
NC score	0.834320 (rank : 5)	θ value	1.85889e-29 (rank : 8)
Query Neighborhood Hits	118	Target Neighborhood Hits	120	Shared Neighborhood Hits	87
SwissProt Accessions	O60462, O14820, O14821	Gene names	NRP2, VEGF165R2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

NRP1_MOUSE
NC score	0.820927 (rank : 6)	θ value	1.12775e-26 (rank : 13)
Query Neighborhood Hits	118	Target Neighborhood Hits	120	Shared Neighborhood Hits	86
SwissProt Accessions	P97333	Gene names	Nrp1, Nrp
Domain Architecture
Description	Neuropilin-1 precursor (A5 protein).

NRP1_HUMAN
NC score	0.820043 (rank : 7)	θ value	2.51237e-26 (rank : 15)
Query Neighborhood Hits	118	Target Neighborhood Hits	119	Shared Neighborhood Hits	87
SwissProt Accessions	O14786, O60461, Q96IH5	Gene names	NRP1, NRP, VEGF165R
Domain Architecture
Description	Neuropilin-1 precursor (Vascular endothelial cell growth factor 165 receptor) (CD304 antigen).

DCBD1_MOUSE
NC score	0.751220 (rank : 8)	θ value	3.1488e-53 (rank : 4)
Query Neighborhood Hits	118	Target Neighborhood Hits	89	Shared Neighborhood Hits	65
SwissProt Accessions	Q9D4J3, Q8R327, Q9D696	Gene names	Dcbld1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

XLRS1_MOUSE
NC score	0.699684 (rank : 9)	θ value	4.9032e-22 (rank : 16)
Query Neighborhood Hits	118	Target Neighborhood Hits	32	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Z1L4	Gene names	Rs1, Rs1h, Xlrs1
Domain Architecture
Description	Retinoschisin precursor (X-linked juvenile retinoschisis protein homolog).

XLRS1_HUMAN
NC score	0.699333 (rank : 10)	θ value	1.42661e-21 (rank : 17)
Query Neighborhood Hits	118	Target Neighborhood Hits	32	Shared Neighborhood Hits	32
SwissProt Accessions	O15537	Gene names	RS1, XLRS1
Domain Architecture
Description	Retinoschisin precursor (X-linked juvenile retinoschisis protein).

MFGM_HUMAN
NC score	0.682518 (rank : 11)	θ value	2.59387e-31 (rank : 7)
Query Neighborhood Hits	118	Target Neighborhood Hits	150	Shared Neighborhood Hits	34
SwissProt Accessions	Q08431	Gene names	MFGE8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (HMFG) (Breast epithelial antigen BA46) (MFGM) [Contains: Lactadherin short form; Medin].

PCOC2_MOUSE
NC score	0.640793 (rank : 12)	θ value	1.2105e-12 (rank : 39)
Query Neighborhood Hits	118	Target Neighborhood Hits	73	Shared Neighborhood Hits	63
SwissProt Accessions	Q8R4W6, Q3V1K6, Q9CX06	Gene names	Pcolce2, Pcpe2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

PCOC2_HUMAN
NC score	0.637634 (rank : 13)	θ value	1.33837e-11 (rank : 44)
Query Neighborhood Hits	118	Target Neighborhood Hits	73	Shared Neighborhood Hits	62
SwissProt Accessions	Q9UKZ9, Q9BRH3	Gene names	PCOLCE2, PCPE2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

PCOC1_MOUSE
NC score	0.636314 (rank : 14)	θ value	1.42992e-13 (rank : 30)
Query Neighborhood Hits	118	Target Neighborhood Hits	100	Shared Neighborhood Hits	65
SwissProt Accessions	Q61398, O35113	Gene names	Pcolce, Pcpe1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein) (P14).

PCOC1_HUMAN
NC score	0.631004 (rank : 15)	θ value	9.26847e-13 (rank : 37)
Query Neighborhood Hits	118	Target Neighborhood Hits	146	Shared Neighborhood Hits	64
SwissProt Accessions	Q15113, O14550	Gene names	PCOLCE, PCPE1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein).

MFGM_MOUSE
NC score	0.587284 (rank : 16)	θ value	9.2256e-29 (rank : 10)
Query Neighborhood Hits	118	Target Neighborhood Hits	233	Shared Neighborhood Hits	36
SwissProt Accessions	P21956, P97800, Q3TBN5, Q9R1X9, Q9WTS3	Gene names	Mfge8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (MFGM) (Sperm surface protein SP47) (MP47).

FA5_HUMAN
NC score	0.584040 (rank : 17)	θ value	1.47289e-26 (rank : 14)
Query Neighborhood Hits	118	Target Neighborhood Hits	172	Shared Neighborhood Hits	34
SwissProt Accessions	P12259, Q14285, Q6UPU6	Gene names	F5
Domain Architecture
Description	Coagulation factor V precursor (Activated protein C cofactor) [Contains: Coagulation factor V heavy chain; Coagulation factor V light chain].

FA8_HUMAN
NC score	0.576457 (rank : 18)	θ value	3.87602e-27 (rank : 11)
Query Neighborhood Hits	118	Target Neighborhood Hits	112	Shared Neighborhood Hits	33
SwissProt Accessions	P00451	Gene names	F8, F8C
Domain Architecture
Description	Coagulation factor VIII precursor (Procoagulant component) (Antihemophilic factor) (AHF) [Contains: Factor VIIIa heavy chain, 200 kDa isoform; Factor VIIIa heavy chain, 92 kDa isoform; Factor VIII B chain; Factor VIIIa light chain].

FA8_MOUSE
NC score	0.576101 (rank : 19)	θ value	3.87602e-27 (rank : 12)
Query Neighborhood Hits	118	Target Neighborhood Hits	100	Shared Neighborhood Hits	32
SwissProt Accessions	Q06194	Gene names	F8, Cf8, F8c
Domain Architecture
Description	Coagulation factor VIII precursor (Procoagulant component).

CUZD1_HUMAN
NC score	0.561816 (rank : 20)	θ value	7.09661e-13 (rank : 36)
Query Neighborhood Hits	118	Target Neighborhood Hits	89	Shared Neighborhood Hits	61
SwissProt Accessions	Q86UP6, Q7Z660, Q7Z661, Q86SG1, Q86UP5, Q9HAR7	Gene names	CUZD1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Transmembrane protein UO-44).

TSG6_HUMAN
NC score	0.557852 (rank : 21)	θ value	2.20605e-14 (rank : 22)
Query Neighborhood Hits	118	Target Neighborhood Hits	91	Shared Neighborhood Hits	62
SwissProt Accessions	P98066, Q8WWI9	Gene names	TNFAIP6, TSG6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein) (Hyaluronate-binding protein).

TSG6_MOUSE
NC score	0.555235 (rank : 22)	θ value	6.41864e-14 (rank : 28)
Query Neighborhood Hits	118	Target Neighborhood Hits	91	Shared Neighborhood Hits	62
SwissProt Accessions	O08859	Gene names	Tnfaip6, Tnfip6, Tsg6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein).

MFRP_MOUSE
NC score	0.550284 (rank : 23)	θ value	3.76295e-14 (rank : 24)
Query Neighborhood Hits	118	Target Neighborhood Hits	166	Shared Neighborhood Hits	67
SwissProt Accessions	Q8K480, Q8BPP4	Gene names	Mfrp
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

CUZD1_MOUSE
NC score	0.549274 (rank : 24)	θ value	7.84624e-12 (rank : 43)
Query Neighborhood Hits	118	Target Neighborhood Hits	91	Shared Neighborhood Hits	60
SwissProt Accessions	P70412, Q9CTZ7	Gene names	Cuzd1, Itmap1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Integral membrane-associated protein 1).

BMP1_MOUSE
NC score	0.546436 (rank : 25)	θ value	3.76295e-14 (rank : 23)
Query Neighborhood Hits	118	Target Neighborhood Hits	236	Shared Neighborhood Hits	64
SwissProt Accessions	P98063	Gene names	Bmp1
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

BMP1_HUMAN
NC score	0.546135 (rank : 26)	θ value	2.43908e-13 (rank : 32)
Query Neighborhood Hits	118	Target Neighborhood Hits	233	Shared Neighborhood Hits	64
SwissProt Accessions	P13497, Q13292, Q13872, Q14874, Q99421, Q99422, Q99423, Q9UL38	Gene names	BMP1, PCOLC
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

TLL2_MOUSE
NC score	0.545741 (rank : 27)	θ value	4.16044e-13 (rank : 34)
Query Neighborhood Hits	118	Target Neighborhood Hits	240	Shared Neighborhood Hits	66
SwissProt Accessions	Q9WVM6	Gene names	Tll2
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

TLL2_HUMAN
NC score	0.545686 (rank : 28)	θ value	9.26847e-13 (rank : 38)
Query Neighborhood Hits	118	Target Neighborhood Hits	241	Shared Neighborhood Hits	66
SwissProt Accessions	Q9Y6L7, Q6PJN5, Q9UQ00	Gene names	TLL2, KIAA0932
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

NETO2_HUMAN
NC score	0.545591 (rank : 29)	θ value	6.87365e-08 (rank : 65)
Query Neighborhood Hits	118	Target Neighborhood Hits	109	Shared Neighborhood Hits	64
SwissProt Accessions	Q8NC67, Q7Z381, Q8ND51, Q96SP4, Q9NVY8	Gene names	NETO2, BTCL2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

NETO2_MOUSE
NC score	0.544873 (rank : 30)	θ value	4.0297e-08 (rank : 61)
Query Neighborhood Hits	118	Target Neighborhood Hits	113	Shared Neighborhood Hits	63
SwissProt Accessions	Q8BNJ6, Q5VM49, Q8C4Q8	Gene names	Neto2, Btcl2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

TLL1_HUMAN
NC score	0.544429 (rank : 31)	θ value	1.2105e-12 (rank : 40)
Query Neighborhood Hits	118	Target Neighborhood Hits	236	Shared Neighborhood Hits	66
SwissProt Accessions	O43897, Q96AN3, Q9NQS4	Gene names	TLL1, TLL
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-).

TLL1_MOUSE
NC score	0.542372 (rank : 32)	θ value	6.00763e-12 (rank : 42)
Query Neighborhood Hits	118	Target Neighborhood Hits	237	Shared Neighborhood Hits	64
SwissProt Accessions	Q62381, Q3UTT9, Q8BNP5	Gene names	Tll1, Tll
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-) (mTll).

MFRP_HUMAN
NC score	0.537753 (rank : 33)	θ value	1.74796e-11 (rank : 46)
Query Neighborhood Hits	118	Target Neighborhood Hits	165	Shared Neighborhood Hits	66
SwissProt Accessions	Q9BY79, Q335M3, Q96DQ9	Gene names	MFRP
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

NETO1_MOUSE
NC score	0.535043 (rank : 34)	θ value	1.29631e-06 (rank : 71)
Query Neighborhood Hits	118	Target Neighborhood Hits	109	Shared Neighborhood Hits	64
SwissProt Accessions	Q8R4I7, Q80X39, Q8C4S3, Q8CCM2	Gene names	Neto1, Btcl1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

NETO1_HUMAN
NC score	0.532750 (rank : 35)	θ value	2.21117e-06 (rank : 75)
Query Neighborhood Hits	118	Target Neighborhood Hits	110	Shared Neighborhood Hits	65
SwissProt Accessions	Q8TDF5, Q86W85, Q8ND78, Q8TDF4	Gene names	NETO1, BTCL1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

EDIL3_HUMAN
NC score	0.497220 (rank : 36)	θ value	6.17384e-33 (rank : 5)
Query Neighborhood Hits	118	Target Neighborhood Hits	292	Shared Neighborhood Hits	44
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

EDIL3_MOUSE
NC score	0.488368 (rank : 37)	θ value	1.37539e-32 (rank : 6)
Query Neighborhood Hits	118	Target Neighborhood Hits	317	Shared Neighborhood Hits	41
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

PDGFD_HUMAN
NC score	0.480754 (rank : 38)	θ value	0.000461057 (rank : 83)
Query Neighborhood Hits	118	Target Neighborhood Hits	74	Shared Neighborhood Hits	58
SwissProt Accessions	Q9GZP0, Q9BWV5	Gene names	PDGFD, IEGF, SCDGFB
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor D precursor (PDGF D) (Iris-expressed growth factor) (Spinal cord-derived growth factor B) (SCDGF-B).

DMBT1_MOUSE
NC score	0.451912 (rank : 39)	θ value	2.98157e-11 (rank : 48)
Query Neighborhood Hits	118	Target Neighborhood Hits	134	Shared Neighborhood Hits	65
SwissProt Accessions	Q60997, Q80YC6, Q9JMJ9	Gene names	Dmbt1, Crpd
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (CRP-ductin) (Vomeroglandin).

PDGFD_MOUSE
NC score	0.451547 (rank : 40)	θ value	θ > 10 (rank : 329)
Query Neighborhood Hits	118	Target Neighborhood Hits	72	Shared Neighborhood Hits	57
SwissProt Accessions	Q925I7, Q3URF6, Q8K2L3, Q9D1L8	Gene names	Pdgfd, Scdgfb
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor chain precursor (PDGF D) (Spinal cord- derived growth factor B) (SCDGF-B).

CNTP2_HUMAN
NC score	0.450304 (rank : 41)	θ value	2.60593e-15 (rank : 20)
Query Neighborhood Hits	118	Target Neighborhood Hits	199	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UHC6, Q52LV1, Q5H9Q7, Q9UQ12	Gene names	CNTNAP2, CASPR2, KIAA0868
Domain Architecture
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

CSMD2_HUMAN
NC score	0.446535 (rank : 42)	θ value	1.47974e-10 (rank : 49)
Query Neighborhood Hits	118	Target Neighborhood Hits	188	Shared Neighborhood Hits	68
SwissProt Accessions	Q7Z408, Q5VT59, Q8N963, Q96Q03, Q9H4V7, Q9H4V8, Q9H4V9, Q9H4W0, Q9H4W1, Q9H4W2, Q9H4W3, Q9H4W4, Q9HCY5, Q9HCY6, Q9HCY7	Gene names	CSMD2, KIAA1884
Domain Architecture
Description	CUB and sushi domain-containing protein 2 (CUB and sushi multiple domains protein 2).

CPXM2_MOUSE
NC score	0.443774 (rank : 43)	θ value	3.07829e-16 (rank : 19)
Query Neighborhood Hits	118	Target Neighborhood Hits	58	Shared Neighborhood Hits	31
SwissProt Accessions	Q9D2L5, O54860, Q8VDQ4	Gene names	Cpxm2, Cpx2
Domain Architecture
Description	Carboxypeptidase-like protein X2 precursor.

LRP12_MOUSE
NC score	0.443031 (rank : 44)	θ value	3.41135e-07 (rank : 70)
Query Neighborhood Hits	118	Target Neighborhood Hits	180	Shared Neighborhood Hits	66
SwissProt Accessions	Q8BUJ9, Q8BWM9	Gene names	Lrp12
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor.

CPXM2_HUMAN
NC score	0.440620 (rank : 45)	θ value	3.07829e-16 (rank : 18)
Query Neighborhood Hits	118	Target Neighborhood Hits	84	Shared Neighborhood Hits	31
SwissProt Accessions	Q8N436	Gene names	CPXM2
Domain Architecture
Description	Carboxypeptidase-like protein X2 precursor.

LRP12_HUMAN
NC score	0.439711 (rank : 46)	θ value	5.26297e-08 (rank : 63)
Query Neighborhood Hits	118	Target Neighborhood Hits	205	Shared Neighborhood Hits	66
SwissProt Accessions	Q9Y561	Gene names	LRP12, ST7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor (Suppressor of tumorigenicity protein 7).

CNTP2_MOUSE
NC score	0.439102 (rank : 47)	θ value	6.41864e-14 (rank : 25)
Query Neighborhood Hits	118	Target Neighborhood Hits	194	Shared Neighborhood Hits	33
SwissProt Accessions	Q9CPW0, Q6P2K4, Q6ZQ31	Gene names	Cntnap2, Kiaa0868
Domain Architecture	No domain graphic available
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

CNTP3_HUMAN
NC score	0.438902 (rank : 48)	θ value	2.0648e-12 (rank : 41)
Query Neighborhood Hits	118	Target Neighborhood Hits	195	Shared Neighborhood Hits	35
SwissProt Accessions	Q9BZ76, Q9C0E9	Gene names	CNTNAP3, CASPR3, KIAA1714
Domain Architecture
Description	Contactin-associated protein-like 3 precursor (Cell recognition molecule Caspr3).

CSMD1_MOUSE
NC score	0.436146 (rank : 49)	θ value	9.59137e-10 (rank : 52)
Query Neighborhood Hits	118	Target Neighborhood Hits	193	Shared Neighborhood Hits	66
SwissProt Accessions	Q923L3, Q8BUV1, Q8BYQ3	Gene names	Csmd1
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

CNTP4_MOUSE
NC score	0.435642 (rank : 50)	θ value	8.38298e-14 (rank : 29)
Query Neighborhood Hits	118	Target Neighborhood Hits	193	Shared Neighborhood Hits	37
SwissProt Accessions	Q99P47	Gene names	Cntnap4, Caspr4
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

CSMD1_HUMAN
NC score	0.434665 (rank : 51)	θ value	3.29651e-10 (rank : 51)
Query Neighborhood Hits	118	Target Neighborhood Hits	176	Shared Neighborhood Hits	65
SwissProt Accessions	Q96PZ7, Q96QU9, Q96RM4	Gene names	CSMD1, KIAA1890
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

CNTP4_HUMAN
NC score	0.432573 (rank : 52)	θ value	1.86753e-13 (rank : 31)
Query Neighborhood Hits	118	Target Neighborhood Hits	187	Shared Neighborhood Hits	35
SwissProt Accessions	Q9C0A0	Gene names	CNTNAP4, CASPR4, KIAA1763
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

CSMD3_HUMAN
NC score	0.431555 (rank : 53)	θ value	8.97725e-08 (rank : 66)
Query Neighborhood Hits	118	Target Neighborhood Hits	199	Shared Neighborhood Hits	65
SwissProt Accessions	Q7Z407, Q96PZ3	Gene names	CSMD3, KIAA1894
Domain Architecture
Description	CUB and sushi domain-containing protein 3 precursor (CUB and sushi multiple domains protein 3).

CUBN_HUMAN
NC score	0.415413 (rank : 54)	θ value	2.20605e-14 (rank : 21)
Query Neighborhood Hits	118	Target Neighborhood Hits	482	Shared Neighborhood Hits	77
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

SEZ6L_HUMAN
NC score	0.415000 (rank : 55)	θ value	0.000786445 (rank : 84)
Query Neighborhood Hits	118	Target Neighborhood Hits	289	Shared Neighborhood Hits	65
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.

CUBN_MOUSE
NC score	0.413380 (rank : 56)	θ value	6.41864e-14 (rank : 26)
Query Neighborhood Hits	118	Target Neighborhood Hits	477	Shared Neighborhood Hits	78
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

CPXM1_HUMAN
NC score	0.410855 (rank : 57)	θ value	4.16044e-13 (rank : 33)
Query Neighborhood Hits	118	Target Neighborhood Hits	69	Shared Neighborhood Hits	32
SwissProt Accessions	Q96SM3, Q6P4G8, Q6UW65, Q9NUB5	Gene names	CPXM1, CPX1, CPXM
Domain Architecture
Description	Probable carboxypeptidase X1 precursor (EC 3.4.17.-) (Metallocarboxypeptidase CPX-1).

DMBT1_HUMAN
NC score	0.404183 (rank : 58)	θ value	5.43371e-13 (rank : 35)
Query Neighborhood Hits	118	Target Neighborhood Hits	152	Shared Neighborhood Hits	64
SwissProt Accessions	Q9UGM3, Q59EX0, Q5JR26, Q6MZN4, Q96DU4, Q9UGM2, Q9UJ57, Q9UKJ4, Q9Y211, Q9Y4V9	Gene names	DMBT1, GP340
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (Glycoprotein 340) (Gp-340) (Surfactant pulmonary-associated D-binding protein).

CNTP1_HUMAN
NC score	0.403071 (rank : 59)	θ value	1.38499e-08 (rank : 59)
Query Neighborhood Hits	118	Target Neighborhood Hits	196	Shared Neighborhood Hits	33
SwissProt Accessions	P78357	Gene names	CNTNAP1, CASPR, NRXN4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (p190).

CNTP1_MOUSE
NC score	0.402303 (rank : 60)	θ value	5.26297e-08 (rank : 62)
Query Neighborhood Hits	118	Target Neighborhood Hits	183	Shared Neighborhood Hits	33
SwissProt Accessions	O54991	Gene names	Cntnap1, Nrxn4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (Paranodin) (NCP1) (MHDNIV).

CPXM1_MOUSE
NC score	0.399664 (rank : 61)	θ value	2.52405e-10 (rank : 50)
Query Neighborhood Hits	118	Target Neighborhood Hits	63	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Z100, Q99LA3	Gene names	Cpxm1, Cpx1, Cpxm
Domain Architecture
Description	Probable carboxypeptidase X1 precursor (EC 3.4.17.-) (Metallocarboxypeptidase CPX-1).

LRP3_HUMAN
NC score	0.370852 (rank : 62)	θ value	1.87187e-05 (rank : 78)
Query Neighborhood Hits	118	Target Neighborhood Hits	280	Shared Neighborhood Hits	66
SwissProt Accessions	O75074	Gene names	LRP3
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 3 precursor (hLRp105).

GP126_HUMAN
NC score	0.368947 (rank : 63)	θ value	6.41864e-14 (rank : 27)
Query Neighborhood Hits	118	Target Neighborhood Hits	187	Shared Neighborhood Hits	63
SwissProt Accessions	Q86SQ4, Q6MZU7, Q8NC14, Q96JW0	Gene names	GPR126
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 126 precursor.

C1R_HUMAN
NC score	0.327821 (rank : 64)	θ value	6.21693e-09 (rank : 57)
Query Neighborhood Hits	118	Target Neighborhood Hits	364	Shared Neighborhood Hits	60
SwissProt Accessions	P00736, Q8J012	Gene names	C1R
Domain Architecture
Description	Complement C1r subcomponent precursor (EC 3.4.21.41) (Complement component 1, r subcomponent) [Contains: Complement C1r subcomponent heavy chain; Complement C1r subcomponent light chain].

C1RA_MOUSE
NC score	0.326540 (rank : 65)	θ value	1.63604e-09 (rank : 53)
Query Neighborhood Hits	118	Target Neighborhood Hits	379	Shared Neighborhood Hits	61
SwissProt Accessions	Q8CG16, Q99KI6, Q9ET60	Gene names	C1ra, C1r
Domain Architecture
Description	Complement C1r-A subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-A subcomponent) [Contains: Complement C1r-A subcomponent heavy chain; Complement C1r-A subcomponent light chain].

C1S_HUMAN
NC score	0.325592 (rank : 66)	θ value	1.63604e-09 (rank : 54)
Query Neighborhood Hits	118	Target Neighborhood Hits	359	Shared Neighborhood Hits	62
SwissProt Accessions	P09871, Q9UCU7, Q9UCU8, Q9UCU9, Q9UCV0, Q9UCV1, Q9UCV2, Q9UCV3, Q9UCV4, Q9UCV5, Q9UM14	Gene names	C1S
Domain Architecture
Description	Complement C1s subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s subcomponent heavy chain; Complement C1s subcomponent light chain].

CS1A_MOUSE
NC score	0.323637 (rank : 67)	θ value	6.21693e-09 (rank : 58)
Query Neighborhood Hits	118	Target Neighborhood Hits	360	Shared Neighborhood Hits	63
SwissProt Accessions	Q8CG14, Q8BJC4, Q8CH28, Q8VBY4	Gene names	C1sa, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-A subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-A subcomponent heavy chain; Complement C1s-A subcomponent light chain].

C1RB_MOUSE
NC score	0.322226 (rank : 68)	θ value	2.79066e-09 (rank : 55)
Query Neighborhood Hits	118	Target Neighborhood Hits	380	Shared Neighborhood Hits	61
SwissProt Accessions	Q8CFG9	Gene names	C1rb, C1r
Domain Architecture	No domain graphic available
Description	Complement C1r-B subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-B subcomponent) [Contains: Complement C1r-B subcomponent heavy chain; Complement C1r-B subcomponent light chain].

CS1B_MOUSE
NC score	0.320811 (rank : 69)	θ value	2.79066e-09 (rank : 56)
Query Neighborhood Hits	118	Target Neighborhood Hits	361	Shared Neighborhood Hits	63
SwissProt Accessions	Q8CFG8	Gene names	C1sb, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-B subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-B subcomponent heavy chain; Complement C1s-B subcomponent light chain].

MASP2_HUMAN
NC score	0.316223 (rank : 70)	θ value	6.87365e-08 (rank : 64)
Query Neighborhood Hits	118	Target Neighborhood Hits	364	Shared Neighborhood Hits	62
SwissProt Accessions	O00187, O75754, Q5TEQ5, Q5TER0, Q96QG4, Q9BZH0, Q9H498, Q9H499, Q9UBP3, Q9ULC7, Q9UMV3, Q9Y270	Gene names	MASP2
Domain Architecture
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

MASP1_HUMAN
NC score	0.312467 (rank : 71)	θ value	2.61198e-07 (rank : 69)
Query Neighborhood Hits	118	Target Neighborhood Hits	369	Shared Neighborhood Hits	64
SwissProt Accessions	P48740, O95570, Q9UF09	Gene names	MASP1, CRARF, CRARF1, PRSS5
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) (Mannose-binding protein- associated serine protease) (MASP-1) [Contains: Complement-activating component of Ra-reactive factor heavy chain; Complement-activating component of Ra-reactive factor light chain].

MASP1_MOUSE
NC score	0.308358 (rank : 72)	θ value	8.97725e-08 (rank : 67)
Query Neighborhood Hits	118	Target Neighborhood Hits	364	Shared Neighborhood Hits	63
SwissProt Accessions	P98064	Gene names	Masp1, Crarf
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) [Contains: Complement- activating component of Ra-reactive factor heavy chain; Complement- activating component of Ra-reactive factor light chain].

MASP2_MOUSE
NC score	0.306785 (rank : 73)	θ value	3.19293e-05 (rank : 80)
Query Neighborhood Hits	118	Target Neighborhood Hits	382	Shared Neighborhood Hits	61
SwissProt Accessions	Q91WP0, Q9QXA4, Q9QXD2, Q9QXD5, Q9Z338	Gene names	Masp2
Domain Architecture	No domain graphic available
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

KREM1_HUMAN
NC score	0.293626 (rank : 74)	θ value	0.0563607 (rank : 90)
Query Neighborhood Hits	118	Target Neighborhood Hits	90	Shared Neighborhood Hits	59
SwissProt Accessions	Q96MU8, Q5TIB9, Q6P3X6, Q9BY70, Q9UGS5, Q9UGU1	Gene names	KREMEN1, KREMEN, KRM1
Domain Architecture
Description	Kremen protein 1 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 1) (Dickkopf receptor).

KREM1_MOUSE
NC score	0.286246 (rank : 75)	θ value	0.0252991 (rank : 88)
Query Neighborhood Hits	118	Target Neighborhood Hits	92	Shared Neighborhood Hits	57
SwissProt Accessions	Q99N43	Gene names	Kremen1, Kremen
Domain Architecture
Description	Kremen protein 1 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 1) (Dickkopf receptor).

KREM2_HUMAN
NC score	0.264116 (rank : 76)	θ value	θ > 10 (rank : 265)
Query Neighborhood Hits	118	Target Neighborhood Hits	93	Shared Neighborhood Hits	55
SwissProt Accessions	Q8NCW0, Q8N2J4, Q8NCW1, Q96GL8, Q9BTP9	Gene names	KREMEN2, KRM2
Domain Architecture
Description	Kremen protein 2 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 2) (Dickkopf receptor 2).

ST14_MOUSE
NC score	0.241798 (rank : 77)	θ value	1.29631e-06 (rank : 73)
Query Neighborhood Hits	118	Target Neighborhood Hits	419	Shared Neighborhood Hits	65
SwissProt Accessions	P56677	Gene names	St14, Prss14
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Epithin).

ST14_HUMAN
NC score	0.240319 (rank : 78)	θ value	1.29631e-06 (rank : 72)
Query Neighborhood Hits	118	Target Neighborhood Hits	409	Shared Neighborhood Hits	65
SwissProt Accessions	Q9Y5Y6, Q9BS01, Q9H3S0, Q9HB36, Q9HCA3	Gene names	ST14, PRSS14, SNC19, TADG15
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Matriptase) (Membrane-type serine protease 1) (MT-SP1) (Prostamin) (Serine protease TADG-15) (Tumor-associated differentially-expressed gene 15 protein).

KREM2_MOUSE
NC score	0.236980 (rank : 79)	θ value	θ > 10 (rank : 266)
Query Neighborhood Hits	118	Target Neighborhood Hits	90	Shared Neighborhood Hits	55
SwissProt Accessions	Q8K1S7	Gene names	Kremen2
Domain Architecture
Description	Kremen protein 2 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 2) (Dickkopf receptor 2).

ENTK_MOUSE
NC score	0.221787 (rank : 80)	θ value	1.09739e-05 (rank : 77)
Query Neighborhood Hits	118	Target Neighborhood Hits	338	Shared Neighborhood Hits	68
SwissProt Accessions	P97435	Gene names	Prss7, Entk
Domain Architecture
Description	Enteropeptidase (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

ATRN_HUMAN
NC score	0.205577 (rank : 81)	θ value	1.06291 (rank : 96)
Query Neighborhood Hits	118	Target Neighborhood Hits	525	Shared Neighborhood Hits	57
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

ATRN_MOUSE
NC score	0.202718 (rank : 82)	θ value	1.06291 (rank : 97)
Query Neighborhood Hits	118	Target Neighborhood Hits	519	Shared Neighborhood Hits	59
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

ENTK_HUMAN
NC score	0.201650 (rank : 83)	θ value	3.19293e-05 (rank : 79)
Query Neighborhood Hits	118	Target Neighborhood Hits	310	Shared Neighborhood Hits	67
SwissProt Accessions	P98073	Gene names	PRSS7, ENTK
Domain Architecture
Description	Enteropeptidase precursor (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

LRP10_MOUSE
NC score	0.179992 (rank : 84)	θ value	0.125558 (rank : 91)
Query Neighborhood Hits	118	Target Neighborhood Hits	169	Shared Neighborhood Hits	38
SwissProt Accessions	Q7TQH7, Q7TS95, Q921T0, Q9EPE8	Gene names	Lrp10, Lrp9
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

CRLD2_HUMAN
NC score	0.163343 (rank : 85)	θ value	0.000121331 (rank : 81)
Query Neighborhood Hits	118	Target Neighborhood Hits	29	Shared Neighborhood Hits	11
SwissProt Accessions	Q9H0B8, Q6P590, Q6UWH0, Q6UXC6, Q96IB1, Q96K61	Gene names	CRISPLD2, CRISP11, LCRISP2
Domain Architecture	No domain graphic available
Description	Cysteine-rich secretory protein LCCL domain-containing 2 precursor (LCCL domain-containing cysteine-rich secretory protein 2) (Cysteine- rich secretory protein 11) (CRISP-11).

SCUB3_MOUSE
NC score	0.157818 (rank : 86)	θ value	1.06291 (rank : 99)
Query Neighborhood Hits	118	Target Neighborhood Hits	442	Shared Neighborhood Hits	65
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SCUB3_HUMAN
NC score	0.156121 (rank : 87)	θ value	1.38821 (rank : 101)
Query Neighborhood Hits	118	Target Neighborhood Hits	428	Shared Neighborhood Hits	65
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

LRP10_HUMAN
NC score	0.153550 (rank : 88)	θ value	1.06291 (rank : 98)
Query Neighborhood Hits	118	Target Neighborhood Hits	197	Shared Neighborhood Hits	35
SwissProt Accessions	Q7Z4F1, O95882, Q86T02, Q8NCZ4, Q9HC42, Q9UG33	Gene names	LRP10
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

DDR2_MOUSE
NC score	0.150645 (rank : 89)	θ value	1.74796e-11 (rank : 45)
Query Neighborhood Hits	118	Target Neighborhood Hits	813	Shared Neighborhood Hits	32
SwissProt Accessions	Q62371	Gene names	Ddr2, Ntrkr3, Tkt, Tyro10
Domain Architecture
Description	Discoidin domain-containing receptor 2 precursor (EC 2.7.10.1) (Discoidin domain receptor 2) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO 10) (Neurotrophic tyrosine kinase, receptor-related 3) (CD167b antigen).

DDR2_HUMAN
NC score	0.149578 (rank : 90)	θ value	2.28291e-11 (rank : 47)
Query Neighborhood Hits	118	Target Neighborhood Hits	818	Shared Neighborhood Hits	32
SwissProt Accessions	Q16832	Gene names	DDR2, NTRKR3, TKT, TYRO10
Domain Architecture
Description	Discoidin domain-containing receptor 2 precursor (EC 2.7.10.1) (Discoidin domain receptor 2) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO 10) (Neurotrophic tyrosine kinase, receptor-related 3) (CD167b antigen).

CRLD1_MOUSE
NC score	0.143036 (rank : 91)	θ value	0.00102713 (rank : 86)
Query Neighborhood Hits	118	Target Neighborhood Hits	23	Shared Neighborhood Hits	11
SwissProt Accessions	Q8CGD2, Q8K018, Q99MM6	Gene names	Crispld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich secretory protein LCCL domain-containing 1 precursor (CocoaCrisp).

CRLD1_HUMAN
NC score	0.141592 (rank : 92)	θ value	0.00102713 (rank : 85)
Query Neighborhood Hits	118	Target Neighborhood Hits	25	Shared Neighborhood Hits	11
SwissProt Accessions	Q9H336	Gene names	CRISPLD1, CRISP10, LCRISP1
Domain Architecture	No domain graphic available
Description	Cysteine-rich secretory protein LCCL domain-containing 1 precursor (LCCL domain-containing cysteine-rich secretory protein 1) (Cysteine- rich secretory protein 10) (CRISP-10) (Trypsin inhibitor Hl) (CocoaCrisp).

VITRN_HUMAN
NC score	0.138701 (rank : 93)	θ value	1.69304e-06 (rank : 74)
Query Neighborhood Hits	118	Target Neighborhood Hits	63	Shared Neighborhood Hits	11
SwissProt Accessions	Q6UXI7, Q6P7T3, Q96DT1	Gene names	VIT
Domain Architecture	No domain graphic available
Description	Vitrin precursor.

MEP1B_MOUSE
NC score	0.136753 (rank : 94)	θ value	θ > 10 (rank : 311)
Query Neighborhood Hits	118	Target Neighborhood Hits	127	Shared Neighborhood Hits	14
SwissProt Accessions	Q61847	Gene names	Mep1b, Mep-1b
Domain Architecture
Description	Meprin A subunit beta precursor (EC 3.4.24.18) (Endopeptidase-2).

DDR1_HUMAN
NC score	0.135966 (rank : 95)	θ value	3.08544e-08 (rank : 60)
Query Neighborhood Hits	118	Target Neighborhood Hits	819	Shared Neighborhood Hits	32
SwissProt Accessions	Q08345, Q14196, Q16562, Q5ST12, Q9UD37	Gene names	DDR1, CAK, EDDR1, RTK6, TRKE
Domain Architecture
Description	Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (TRK E) (Protein-tyrosine kinase RTK 6) (HGK2) (CD167a antigen).

VITRN_MOUSE
NC score	0.134920 (rank : 96)	θ value	3.77169e-06 (rank : 76)
Query Neighborhood Hits	118	Target Neighborhood Hits	68	Shared Neighborhood Hits	11
SwissProt Accessions	Q8VHI5, Q3TZ47, Q8BQ41, Q8K047, Q9CYZ1	Gene names	Vit
Domain Architecture	No domain graphic available
Description	Vitrin precursor.

COCH_HUMAN
NC score	0.131007 (rank : 97)	θ value	0.00020696 (rank : 82)
Query Neighborhood Hits	118	Target Neighborhood Hits	51	Shared Neighborhood Hits	11
SwissProt Accessions	O43405	Gene names	COCH, COCH5B2
Domain Architecture
Description	Cochlin precursor (COCH-5B2).

MEP1A_HUMAN
NC score	0.130064 (rank : 98)	θ value	θ > 10 (rank : 308)
Query Neighborhood Hits	118	Target Neighborhood Hits	162	Shared Neighborhood Hits	18
SwissProt Accessions	Q16819	Gene names	MEP1A
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit alpha) (PABA peptide hydrolase) (PPH alpha).

DDR1_MOUSE
NC score	0.129487 (rank : 99)	θ value	2.61198e-07 (rank : 68)
Query Neighborhood Hits	118	Target Neighborhood Hits	818	Shared Neighborhood Hits	32
SwissProt Accessions	Q03146	Gene names	Ddr1, Cak, Eddr1, Mpk6
Domain Architecture
Description	Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (Protein-tyrosine kinase MPK-6) (CD167a antigen).

MEP1A_MOUSE
NC score	0.124283 (rank : 100)	θ value	θ > 10 (rank : 309)
Query Neighborhood Hits	118	Target Neighborhood Hits	166	Shared Neighborhood Hits	17
SwissProt Accessions	P28825	Gene names	Mep1a
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (MEP-1).

COCH_MOUSE
NC score	0.122253 (rank : 101)	θ value	0.00175202 (rank : 87)
Query Neighborhood Hits	118	Target Neighborhood Hits	51	Shared Neighborhood Hits	11
SwissProt Accessions	Q62507, Q3TAF5, Q9QWK6	Gene names	Coch
Domain Architecture
Description	Cochlin precursor (COCH-5B2).

MEP1B_HUMAN
NC score	0.120729 (rank : 102)	θ value	θ > 10 (rank : 310)
Query Neighborhood Hits	118	Target Neighborhood Hits	98	Shared Neighborhood Hits	11
SwissProt Accessions	Q16820, Q670J1	Gene names	MEP1B
Domain Architecture
Description	Meprin A subunit beta precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit beta) (PABA peptide hydrolase) (PPH beta).

ASTL_MOUSE
NC score	0.118628 (rank : 103)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	118	Target Neighborhood Hits	20	Shared Neighborhood Hits	6
SwissProt Accessions	Q6HA09, Q8BMA1	Gene names	Astl
Domain Architecture	No domain graphic available
Description	Astacin-like metalloendopeptidase precursor (EC 3.4.-.-) (Oocyte astacin) (Ovastacin).

HEPH_MOUSE
NC score	0.118439 (rank : 104)	θ value	θ > 10 (rank : 238)
Query Neighborhood Hits	118	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z0Z4, Q6ZQ65, Q80Y80, Q8C4S2	Gene names	Heph, Kiaa0698
Domain Architecture	No domain graphic available
Description	Hephaestin precursor (EC 1.-.-.-).

CERU_HUMAN
NC score	0.117557 (rank : 105)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	118	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	P00450, Q14063, Q2PP18, Q9UKS4	Gene names	CP
Domain Architecture
Description	Ceruloplasmin precursor (EC 1.16.3.1) (Ferroxidase).

HEPH_HUMAN
NC score	0.116847 (rank : 106)	θ value	θ > 10 (rank : 237)
Query Neighborhood Hits	118	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BQS7, O75180, Q6UW45, Q9C058	Gene names	HEPH, KIAA0698
Domain Architecture	No domain graphic available
Description	Hephaestin precursor (EC 1.-.-.-).

CERU_MOUSE
NC score	0.116361 (rank : 107)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	118	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	Q61147	Gene names	Cp
Domain Architecture
Description	Ceruloplasmin precursor (EC 1.16.3.1) (Ferroxidase).

ASTL_HUMAN
NC score	0.114582 (rank : 108)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	118	Target Neighborhood Hits	252	Shared Neighborhood Hits	7
SwissProt Accessions	Q6HA08	Gene names	ASTL
Domain Architecture	No domain graphic available
Description	Astacin-like metalloendopeptidase precursor (EC 3.4.-.-) (Oocyte astacin) (Ovastacin).

TMPS7_HUMAN
NC score	0.111053 (rank : 109)	θ value	θ > 10 (rank : 371)
Query Neighborhood Hits	118	Target Neighborhood Hits	275	Shared Neighborhood Hits	53
SwissProt Accessions	Q7RTY8	Gene names	TMPRSS7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

GLPC_HUMAN
NC score	0.108072 (rank : 110)	θ value	θ > 10 (rank : 233)
Query Neighborhood Hits	118	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	P04921, Q92642	Gene names	GYPC, GPC
Domain Architecture
Description	Glycophorin C (PAS-2') (Glycoprotein beta) (GLPC) (Glycoconnectin) (Sialoglycoprotein D) (Glycophorin D) (GPD) (CD236 antigen).

TMPS7_MOUSE
NC score	0.105639 (rank : 111)	θ value	θ > 10 (rank : 372)
Query Neighborhood Hits	118	Target Neighborhood Hits	275	Shared Neighborhood Hits	52
SwissProt Accessions	Q8BIK6	Gene names	Tmprss7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

TMPS6_MOUSE
NC score	0.097974 (rank : 112)	θ value	θ > 10 (rank : 370)
Query Neighborhood Hits	118	Target Neighborhood Hits	341	Shared Neighborhood Hits	49
SwissProt Accessions	Q9DBI0, Q6PF94	Gene names	Tmprss6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

TMPS6_HUMAN
NC score	0.096727 (rank : 113)	θ value	θ > 10 (rank : 369)
Query Neighborhood Hits	118	Target Neighborhood Hits	338	Shared Neighborhood Hits	45
SwissProt Accessions	Q8IU80, Q5TI06, Q6UXD8, Q8IUE2, Q8IXV8	Gene names	TMPRSS6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

NRX1A_HUMAN
NC score	0.096706 (rank : 114)	θ value	θ > 10 (rank : 324)
Query Neighborhood Hits	118	Target Neighborhood Hits	170	Shared Neighborhood Hits	17
SwissProt Accessions	Q9ULB1, O60323, Q53TJ9, Q53TQ1, Q9C079, Q9C080, Q9C081, Q9H3M2, Q9UDM6	Gene names	NRXN1, KIAA0578
Domain Architecture
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

LYAM3_MOUSE
NC score	0.095664 (rank : 115)	θ value	θ > 10 (rank : 293)
Query Neighborhood Hits	118	Target Neighborhood Hits	390	Shared Neighborhood Hits	36
SwissProt Accessions	Q01102	Gene names	Selp, Grmp
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

NRX1A_MOUSE
NC score	0.095621 (rank : 116)	θ value	θ > 10 (rank : 325)
Query Neighborhood Hits	118	Target Neighborhood Hits	164	Shared Neighborhood Hits	17
SwissProt Accessions	Q9CS84, O88722, Q80Y87, Q8CHE6	Gene names	Nrxn1, Kiaa0578
Domain Architecture	No domain graphic available
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

C4BB_HUMAN
NC score	0.094881 (rank : 117)	θ value	θ > 10 (rank : 134)
Query Neighborhood Hits	118	Target Neighborhood Hits	77	Shared Neighborhood Hits	16
SwissProt Accessions	P20851	Gene names	C4BPB
Domain Architecture
Description	C4b-binding protein beta chain precursor.

CBPE_HUMAN
NC score	0.094869 (rank : 118)	θ value	θ > 10 (rank : 140)
Query Neighborhood Hits	118	Target Neighborhood Hits	28	Shared Neighborhood Hits	5
SwissProt Accessions	P16870, Q9UIU9	Gene names	CPE
Domain Architecture
Description	Carboxypeptidase E precursor (EC 3.4.17.10) (CPE) (Carboxypeptidase H) (CPH) (Enkephalin convertase) (Prohormone-processing carboxypeptidase).

HPT_HUMAN
NC score	0.094867 (rank : 119)	θ value	θ > 10 (rank : 244)
Query Neighborhood Hits	118	Target Neighborhood Hits	184	Shared Neighborhood Hits	16
SwissProt Accessions	P00738, P00737, Q2PP15, Q3B7J0, Q6LBY9	Gene names	HP
Domain Architecture
Description	Haptoglobin precursor [Contains: Haptoglobin alpha chain; Haptoglobin beta chain].

HPT_MOUSE
NC score	0.094210 (rank : 120)	θ value	θ > 10 (rank : 245)
Query Neighborhood Hits	118	Target Neighborhood Hits	178	Shared Neighborhood Hits	15
SwissProt Accessions	Q61646	Gene names	Hp
Domain Architecture
Description	Haptoglobin precursor [Contains: Haptoglobin alpha chain; Haptoglobin beta chain].

CBPZ_HUMAN
NC score	0.094144 (rank : 121)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	118	Target Neighborhood Hits	69	Shared Neighborhood Hits	6
SwissProt Accessions	Q66K79, O00520, Q96MX2	Gene names	CPZ
Domain Architecture	No domain graphic available
Description	Carboxypeptidase Z precursor (EC 3.4.17.-) (CPZ).

CBPE_MOUSE
NC score	0.094120 (rank : 122)	θ value	θ > 10 (rank : 141)
Query Neighborhood Hits	118	Target Neighborhood Hits	29	Shared Neighborhood Hits	4
SwissProt Accessions	Q00493, Q64439	Gene names	Cpe
Domain Architecture
Description	Carboxypeptidase E precursor (EC 3.4.17.10) (CPE) (Carboxypeptidase H) (CPH) (Enkephalin convertase) (Prohormone-processing carboxypeptidase).

PROZ_HUMAN
NC score	0.093051 (rank : 123)	θ value	θ > 10 (rank : 340)
Query Neighborhood Hits	118	Target Neighborhood Hits	422	Shared Neighborhood Hits	36
SwissProt Accessions	P22891, Q15213	Gene names	PROZ
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

CBPN_MOUSE
NC score	0.092934 (rank : 124)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	118	Target Neighborhood Hits	26	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JJN5, Q91WM9	Gene names	Cpn1
Domain Architecture	No domain graphic available
Description	Carboxypeptidase N catalytic chain precursor (EC 3.4.17.3) (CPN) (Carboxypeptidase N polypeptide 1) (Carboxypeptidase N small subunit).

LYAM2_HUMAN
NC score	0.092889 (rank : 125)	θ value	θ > 10 (rank : 290)
Query Neighborhood Hits	118	Target Neighborhood Hits	394	Shared Neighborhood Hits	34
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

CBPN_HUMAN
NC score	0.092606 (rank : 126)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	118	Target Neighborhood Hits	32	Shared Neighborhood Hits	4
SwissProt Accessions	P15169	Gene names	CPN1, ACBP
Domain Architecture
Description	Carboxypeptidase N catalytic chain precursor (EC 3.4.17.3) (CPN) (Carboxypeptidase N polypeptide 1) (Carboxypeptidase N small subunit) (Lysine carboxypeptidase) (Arginine carboxypeptidase) (Kininase-1) (Serum carboxypeptidase N) (SCPN) (Anaphylatoxin inactivator) (Plasma carboxypeptidase B).

CBPZ_MOUSE
NC score	0.092403 (rank : 127)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	118	Target Neighborhood Hits	77	Shared Neighborhood Hits	6
SwissProt Accessions	Q8R4V4	Gene names	Cpz
Domain Architecture	No domain graphic available
Description	Carboxypeptidase Z precursor (EC 3.4.17.-) (CPZ).

NRX3A_HUMAN
NC score	0.092352 (rank : 128)	θ value	θ > 10 (rank : 327)
Query Neighborhood Hits	118	Target Neighborhood Hits	164	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y4C0, O95378, Q9NS47, Q9P1V3, Q9P1V6, Q9UIE2, Q9UIE3, Q9ULA5, Q9Y486	Gene names	NRXN3, KIAA0743
Domain Architecture
Description	Neurexin-3-alpha precursor (Neurexin III-alpha).

HPTR_HUMAN
NC score	0.092187 (rank : 129)	θ value	θ > 10 (rank : 243)
Query Neighborhood Hits	118	Target Neighborhood Hits	166	Shared Neighborhood Hits	14
SwissProt Accessions	P00739, Q7LE20, Q92658, Q92659, Q9ULB0	Gene names	HPR
Domain Architecture
Description	Haptoglobin-related protein precursor.

PROZ_MOUSE
NC score	0.090669 (rank : 130)	θ value	θ > 10 (rank : 341)
Query Neighborhood Hits	118	Target Neighborhood Hits	410	Shared Neighborhood Hits	35
SwissProt Accessions	Q9CQW3	Gene names	Proz
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

FA10_HUMAN
NC score	0.089243 (rank : 131)	θ value	θ > 10 (rank : 206)
Query Neighborhood Hits	118	Target Neighborhood Hits	431	Shared Neighborhood Hits	36
SwissProt Accessions	P00742, Q14340	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) (Stuart- Prower factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

FA9_HUMAN
NC score	0.088857 (rank : 132)	θ value	θ > 10 (rank : 213)
Query Neighborhood Hits	118	Target Neighborhood Hits	421	Shared Neighborhood Hits	38
SwissProt Accessions	P00740	Gene names	F9
Domain Architecture
Description	Coagulation factor IX precursor (EC 3.4.21.22) (Christmas factor) (Plasma thromboplastin component) (PTC) [Contains: Coagulation factor IXa light chain; Coagulation factor IXa heavy chain].

CR2_HUMAN
NC score	0.087024 (rank : 133)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	118	Target Neighborhood Hits	89	Shared Neighborhood Hits	15
SwissProt Accessions	P20023, Q13866, Q14212	Gene names	CR2, C3DR
Domain Architecture
Description	Complement receptor type 2 precursor (Cr2) (Complement C3d receptor) (Epstein-Barr virus receptor) (EBV receptor) (CD21 antigen).

LYAM2_MOUSE
NC score	0.086704 (rank : 134)	θ value	θ > 10 (rank : 291)
Query Neighborhood Hits	118	Target Neighborhood Hits	420	Shared Neighborhood Hits	36
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

CR2_MOUSE
NC score	0.086392 (rank : 135)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	118	Target Neighborhood Hits	101	Shared Neighborhood Hits	15
SwissProt Accessions	P19070	Gene names	Cr2
Domain Architecture
Description	Complement receptor type 2 precursor (Cr2) (Complement C3d receptor) (CD21 antigen).

CFAB_MOUSE
NC score	0.085060 (rank : 136)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	118	Target Neighborhood Hits	262	Shared Neighborhood Hits	23
SwissProt Accessions	P04186	Gene names	Cfb, Bf, H2-Bf
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

HABP2_HUMAN
NC score	0.084696 (rank : 137)	θ value	θ > 10 (rank : 235)
Query Neighborhood Hits	118	Target Neighborhood Hits	431	Shared Neighborhood Hits	31
SwissProt Accessions	Q14520, O00663	Gene names	HABP2, HGFAL, PHBP
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) (Hepatocyte growth factor activator-like protein) (Factor VII-activating protease) (Factor seven-activating protease) (FSAP) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

CBPM_MOUSE
NC score	0.084627 (rank : 138)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	118	Target Neighborhood Hits	30	Shared Neighborhood Hits	4
SwissProt Accessions	Q80V42, Q497S5, Q9CYH8	Gene names	Cpm
Domain Architecture	No domain graphic available
Description	Carboxypeptidase M precursor (EC 3.4.17.12) (CPM).

FA7_MOUSE
NC score	0.084327 (rank : 139)	θ value	θ > 10 (rank : 212)
Query Neighborhood Hits	118	Target Neighborhood Hits	374	Shared Neighborhood Hits	34
SwissProt Accessions	P70375, Q61109	Gene names	F7, Cf7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) [Contains: Factor VII light chain; Factor VII heavy chain].

CBPM_HUMAN
NC score	0.084306 (rank : 140)	θ value	θ > 10 (rank : 142)
Query Neighborhood Hits	118	Target Neighborhood Hits	33	Shared Neighborhood Hits	4
SwissProt Accessions	P14384, Q9H2K9	Gene names	CPM
Domain Architecture
Description	Carboxypeptidase M precursor (EC 3.4.17.12) (CPM).

FA10_MOUSE
NC score	0.084230 (rank : 141)	θ value	θ > 10 (rank : 207)
Query Neighborhood Hits	118	Target Neighborhood Hits	435	Shared Neighborhood Hits	33
SwissProt Accessions	O88947, O54740, Q99L32	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

FA7_HUMAN
NC score	0.084133 (rank : 142)	θ value	θ > 10 (rank : 211)
Query Neighborhood Hits	118	Target Neighborhood Hits	404	Shared Neighborhood Hits	35
SwissProt Accessions	P08709, Q14339, Q5JVF2	Gene names	F7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) (SPCA) (Proconvertin) (Eptacog alfa) [Contains: Factor VII light chain; Factor VII heavy chain].

CFAB_HUMAN
NC score	0.083877 (rank : 143)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	118	Target Neighborhood Hits	251	Shared Neighborhood Hits	23
SwissProt Accessions	P00751, O15006, Q29944, Q96HX6, Q9BTF5, Q9BX92	Gene names	CFB, BF
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) (Properdin factor B) (Glycine-rich beta glycoprotein) (GBG) (PBF2) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

HABP2_MOUSE
NC score	0.083698 (rank : 144)	θ value	θ > 10 (rank : 236)
Query Neighborhood Hits	118	Target Neighborhood Hits	445	Shared Neighborhood Hits	31
SwissProt Accessions	Q8K0D2	Gene names	Habp2, Phbp
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

PROS_HUMAN
NC score	0.083253 (rank : 145)	θ value	θ > 10 (rank : 338)
Query Neighborhood Hits	118	Target Neighborhood Hits	340	Shared Neighborhood Hits	35
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

LRP2_HUMAN
NC score	0.082630 (rank : 146)	θ value	θ > 10 (rank : 272)
Query Neighborhood Hits	118	Target Neighborhood Hits	573	Shared Neighborhood Hits	45
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

SSPO_MOUSE
NC score	0.082000 (rank : 147)	θ value	0.0252991 (rank : 89)
Query Neighborhood Hits	118	Target Neighborhood Hits	800	Shared Neighborhood Hits	38
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

CR1_HUMAN
NC score	0.081761 (rank : 148)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	118	Target Neighborhood Hits	108	Shared Neighborhood Hits	15
SwissProt Accessions	P17927, Q16745, Q9UQV2	Gene names	CR1, C3BR
Domain Architecture
Description	Complement receptor type 1 precursor (C3b/C4b receptor) (CD35 antigen).

CFAI_MOUSE
NC score	0.081517 (rank : 149)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	118	Target Neighborhood Hits	290	Shared Neighborhood Hits	27
SwissProt Accessions	Q61129, Q9WU07	Gene names	Cfi, If
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

NRX2A_HUMAN
NC score	0.081366 (rank : 150)	θ value	θ > 10 (rank : 326)
Query Neighborhood Hits	118	Target Neighborhood Hits	614	Shared Neighborhood Hits	19
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

CBPD_HUMAN
NC score	0.081075 (rank : 151)	θ value	θ > 10 (rank : 138)
Query Neighborhood Hits	118	Target Neighborhood Hits	53	Shared Neighborhood Hits	4
SwissProt Accessions	O75976, O15377, Q86SH9, Q86XE6	Gene names	CPD
Domain Architecture
Description	Carboxypeptidase D precursor (EC 3.4.17.22) (Metallocarboxypeptidase D) (gp180).

CBPD_MOUSE
NC score	0.081067 (rank : 152)	θ value	θ > 10 (rank : 139)
Query Neighborhood Hits	118	Target Neighborhood Hits	62	Shared Neighborhood Hits	4
SwissProt Accessions	O89001	Gene names	Cpd
Domain Architecture
Description	Carboxypeptidase D precursor (EC 3.4.17.22) (Metallocarboxypeptidase D) (gp180).

LYAM3_HUMAN
NC score	0.080642 (rank : 153)	θ value	θ > 10 (rank : 292)
Query Neighborhood Hits	118	Target Neighborhood Hits	378	Shared Neighborhood Hits	29
SwissProt Accessions	P16109, Q8IVD1	Gene names	SELP, GMRP
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

APOH_HUMAN
NC score	0.080422 (rank : 154)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	118	Target Neighborhood Hits	75	Shared Neighborhood Hits	15
SwissProt Accessions	P02749, Q9UCN7	Gene names	APOH, B2G1
Domain Architecture
Description	Beta-2-glycoprotein 1 precursor (Beta-2-glycoprotein I) (Apolipoprotein H) (Apo-H) (B2GPI) (Beta(2)GPI) (Activated protein C- binding protein) (APC inhibitor) (Anticardiolipin cofactor).

C4BP_MOUSE
NC score	0.080294 (rank : 155)	θ value	θ > 10 (rank : 136)
Query Neighborhood Hits	118	Target Neighborhood Hits	91	Shared Neighborhood Hits	15
SwissProt Accessions	P08607	Gene names	C4bpa, C4bp
Domain Architecture
Description	C4b-binding protein precursor (C4bp).

ZP3R_MOUSE
NC score	0.079961 (rank : 156)	θ value	θ > 10 (rank : 401)
Query Neighborhood Hits	118	Target Neighborhood Hits	81	Shared Neighborhood Hits	15
SwissProt Accessions	Q60736	Gene names	Zp3r, Sp56
Domain Architecture
Description	Zona pellucida sperm-binding protein 3 receptor precursor (Sperm fertilization protein 56) (sp56).

C4BP_HUMAN
NC score	0.079622 (rank : 157)	θ value	θ > 10 (rank : 135)
Query Neighborhood Hits	118	Target Neighborhood Hits	92	Shared Neighborhood Hits	15
SwissProt Accessions	P04003	Gene names	C4BPA, C4BP
Domain Architecture
Description	C4b-binding protein alpha chain precursor (C4bp) (Proline-rich protein) (PRP).

CO2_MOUSE
NC score	0.079594 (rank : 158)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	118	Target Neighborhood Hits	250	Shared Neighborhood Hits	19
SwissProt Accessions	P21180	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

EGFL7_HUMAN
NC score	0.079274 (rank : 159)	θ value	θ > 10 (rank : 195)
Query Neighborhood Hits	118	Target Neighborhood Hits	325	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

PROC_HUMAN
NC score	0.079040 (rank : 160)	θ value	θ > 10 (rank : 336)
Query Neighborhood Hits	118	Target Neighborhood Hits	406	Shared Neighborhood Hits	31
SwissProt Accessions	P04070, Q15189, Q15190, Q16001	Gene names	PROC
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

MCP_MOUSE
NC score	0.078974 (rank : 161)	θ value	θ > 10 (rank : 306)
Query Neighborhood Hits	118	Target Neighborhood Hits	79	Shared Neighborhood Hits	15
SwissProt Accessions	O88174, Q9R0R9	Gene names	Cd46, Mcp
Domain Architecture	No domain graphic available
Description	Membrane cofactor protein precursor (CD46 antigen).

CFAI_HUMAN
NC score	0.078737 (rank : 162)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	118	Target Neighborhood Hits	289	Shared Neighborhood Hits	28
SwissProt Accessions	P05156, O60442	Gene names	CFI, IF
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

MAMC2_HUMAN
NC score	0.078091 (rank : 163)	θ value	θ > 10 (rank : 294)
Query Neighborhood Hits	118	Target Neighborhood Hits	31	Shared Neighborhood Hits	6
SwissProt Accessions	Q7Z304, Q5VW47, Q8WX43, Q96BM4	Gene names	MAMDC2
Domain Architecture
Description	MAM domain-containing protein 2 precursor.

LDLR_MOUSE
NC score	0.078016 (rank : 164)	θ value	θ > 10 (rank : 268)
Query Neighborhood Hits	118	Target Neighborhood Hits	382	Shared Neighborhood Hits	37
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

SUSD1_HUMAN
NC score	0.077837 (rank : 165)	θ value	θ > 10 (rank : 349)
Query Neighborhood Hits	118	Target Neighborhood Hits	285	Shared Neighborhood Hits	34
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

PROC_MOUSE
NC score	0.077757 (rank : 166)	θ value	θ > 10 (rank : 337)
Query Neighborhood Hits	118	Target Neighborhood Hits	426	Shared Neighborhood Hits	31
SwissProt Accessions	P33587, O35498, Q91WN8, Q99PC6	Gene names	Proc
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

CORIN_HUMAN
NC score	0.077664 (rank : 167)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	118	Target Neighborhood Hits	453	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y5Q5, Q9UHY2	Gene names	CORIN, CRN, TMPRSS10
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Heart-specific serine proteinase ATC2) (Transmembrane protease, serine 10).

PROS_MOUSE
NC score	0.077547 (rank : 168)	θ value	θ > 10 (rank : 339)
Query Neighborhood Hits	118	Target Neighborhood Hits	330	Shared Neighborhood Hits	35
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

GAS6_HUMAN
NC score	0.077541 (rank : 169)	θ value	θ > 10 (rank : 231)
Query Neighborhood Hits	118	Target Neighborhood Hits	348	Shared Neighborhood Hits	34
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

CO2_HUMAN
NC score	0.076814 (rank : 170)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	118	Target Neighborhood Hits	258	Shared Neighborhood Hits	18
SwissProt Accessions	P06681, O19694, Q13904	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

LRP1B_MOUSE
NC score	0.076724 (rank : 171)	θ value	θ > 10 (rank : 270)
Query Neighborhood Hits	118	Target Neighborhood Hits	606	Shared Neighborhood Hits	46
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

C1QR1_MOUSE
NC score	0.076469 (rank : 172)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	118	Target Neighborhood Hits	342	Shared Neighborhood Hits	31
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

LDLR_HUMAN
NC score	0.076330 (rank : 173)	θ value	θ > 10 (rank : 267)
Query Neighborhood Hits	118	Target Neighborhood Hits	375	Shared Neighborhood Hits	38
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LRP1B_HUMAN
NC score	0.076220 (rank : 174)	θ value	θ > 10 (rank : 269)
Query Neighborhood Hits	118	Target Neighborhood Hits	602	Shared Neighborhood Hits	45
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

CORIN_MOUSE
NC score	0.076188 (rank : 175)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	118	Target Neighborhood Hits	451	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Z319	Gene names	Corin, Crn, Lrp4
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4).

CRUM1_HUMAN
NC score	0.075814 (rank : 176)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	118	Target Neighborhood Hits	457	Shared Neighborhood Hits	34
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

FA12_HUMAN
NC score	0.075484 (rank : 177)	θ value	θ > 10 (rank : 210)
Query Neighborhood Hits	118	Target Neighborhood Hits	425	Shared Neighborhood Hits	32
SwissProt Accessions	P00748, P78339	Gene names	F12
Domain Architecture
Description	Coagulation factor XII precursor (EC 3.4.21.38) (Hageman factor) (HAF) [Contains: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Beta-factor XIIa part 2; Coagulation factor XIIa light chain].

EGFL8_MOUSE
NC score	0.075340 (rank : 178)	θ value	θ > 10 (rank : 198)
Query Neighborhood Hits	118	Target Neighborhood Hits	266	Shared Neighborhood Hits	26
SwissProt Accessions	Q6GUQ1, O35447	Gene names	Egfl8, Ng3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8).

HGFA_MOUSE
NC score	0.074567 (rank : 179)	θ value	θ > 10 (rank : 242)
Query Neighborhood Hits	118	Target Neighborhood Hits	419	Shared Neighborhood Hits	31
SwissProt Accessions	Q9R098, Q9JKV4	Gene names	Hgfac
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

CDCP1_HUMAN
NC score	0.074156 (rank : 180)	θ value	0.813845 (rank : 95)
Query Neighborhood Hits	118	Target Neighborhood Hits	33	Shared Neighborhood Hits	20
SwissProt Accessions	Q9H5V8, Q49UB4, Q6NT71, Q6U9Y2, Q8WU91, Q96QU7, Q9H676, Q9H8C2	Gene names	CDCP1, TRASK
Domain Architecture	No domain graphic available
Description	CUB domain-containing protein 1 precursor (Transmembrane and associated with src kinases) (Membrane glycoprotein gp140) (Subtractive immunization M plus HEp3-associated 135 kDa protein) (SIMA135) (CD318 antigen).

NETR_HUMAN
NC score	0.074152 (rank : 181)	θ value	θ > 10 (rank : 312)
Query Neighborhood Hits	118	Target Neighborhood Hits	218	Shared Neighborhood Hits	18
SwissProt Accessions	P56730, Q9UP16	Gene names	PRSS12
Domain Architecture
Description	Neurotrypsin precursor (EC 3.4.21.-) (Motopsin) (Leydin).

MAMC2_MOUSE
NC score	0.074129 (rank : 182)	θ value	θ > 10 (rank : 295)
Query Neighborhood Hits	118	Target Neighborhood Hits	31	Shared Neighborhood Hits	6
SwissProt Accessions	Q8CG85, Q8BM24	Gene names	Mamdc2
Domain Architecture
Description	MAM domain-containing protein 2 precursor.

LRP8_MOUSE
NC score	0.074077 (rank : 183)	θ value	θ > 10 (rank : 279)
Query Neighborhood Hits	118	Target Neighborhood Hits	385	Shared Neighborhood Hits	37
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

LRP1_HUMAN
NC score	0.074021 (rank : 184)	θ value	θ > 10 (rank : 271)
Query Neighborhood Hits	118	Target Neighborhood Hits	617	Shared Neighborhood Hits	47
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

DAF_HUMAN
NC score	0.073712 (rank : 185)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	118	Target Neighborhood Hits	97	Shared Neighborhood Hits	15
SwissProt Accessions	P08174, P09679, P78361	Gene names	CD55, CR, DAF
Domain Architecture
Description	Complement decay-accelerating factor precursor (CD55 antigen).

CRUM1_MOUSE
NC score	0.073511 (rank : 186)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	118	Target Neighborhood Hits	444	Shared Neighborhood Hits	34
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

CFAH_HUMAN
NC score	0.073387 (rank : 187)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	118	Target Neighborhood Hits	101	Shared Neighborhood Hits	15
SwissProt Accessions	P08603, P78435, Q14570, Q38G77, Q5TFM3, Q8N708, Q9NU86	Gene names	CFH, HF, HF1
Domain Architecture
Description	Complement factor H precursor (H factor 1).

CFAH_MOUSE
NC score	0.073075 (rank : 188)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	118	Target Neighborhood Hits	112	Shared Neighborhood Hits	15
SwissProt Accessions	P06909	Gene names	Cfh, Hf1
Domain Architecture
Description	Complement factor H precursor (Protein beta-1-H).

NETR_MOUSE
NC score	0.072769 (rank : 189)	θ value	θ > 10 (rank : 313)
Query Neighborhood Hits	118	Target Neighborhood Hits	216	Shared Neighborhood Hits	18
SwissProt Accessions	O08762	Gene names	Prss12, Bssp3
Domain Architecture
Description	Neurotrypsin precursor (EC 3.4.21.-) (Motopsin) (Brain-specific serine protease 3) (BSSP-3).

GAS6_MOUSE
NC score	0.072651 (rank : 190)	θ value	θ > 10 (rank : 232)
Query Neighborhood Hits	118	Target Neighborhood Hits	343	Shared Neighborhood Hits	35
SwissProt Accessions	Q61592, Q99K57	Gene names	Gas6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

HGFA_HUMAN
NC score	0.072575 (rank : 191)	θ value	θ > 10 (rank : 241)
Query Neighborhood Hits	118	Target Neighborhood Hits	436	Shared Neighborhood Hits	30
SwissProt Accessions	Q04756, Q14726	Gene names	HGFAC
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

CRRY_MOUSE
NC score	0.072399 (rank : 192)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	118	Target Neighborhood Hits	84	Shared Neighborhood Hits	15
SwissProt Accessions	Q64735, Q3TV30, Q58E68, Q61447, Q61449, Q8CF59, Q8K328	Gene names	Crry, Cry
Domain Architecture	No domain graphic available
Description	Complement regulatory protein Crry precursor (Protein p65).

LRP8_HUMAN
NC score	0.072060 (rank : 193)	θ value	θ > 10 (rank : 278)
Query Neighborhood Hits	118	Target Neighborhood Hits	346	Shared Neighborhood Hits	37
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

EGFL8_HUMAN
NC score	0.071773 (rank : 194)	θ value	θ > 10 (rank : 197)
Query Neighborhood Hits	118	Target Neighborhood Hits	270	Shared Neighborhood Hits	26
SwissProt Accessions	Q99944, Q8IV30	Gene names	EGFL8, C6orf8, NG3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8) (Vascular endothelial-statin 2) (VE-statin-2).

MATN2_MOUSE
NC score	0.071619 (rank : 195)	θ value	θ > 10 (rank : 299)
Query Neighborhood Hits	118	Target Neighborhood Hits	356	Shared Neighborhood Hits	31
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

TPA_HUMAN
NC score	0.071610 (rank : 196)	θ value	θ > 10 (rank : 378)
Query Neighborhood Hits	118	Target Neighborhood Hits	324	Shared Neighborhood Hits	24
SwissProt Accessions	P00750, Q15103, Q7Z7N2, Q86YK8, Q9BU99	Gene names	PLAT
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) (Alteplase) (Reteplase) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

CRUM2_HUMAN
NC score	0.071410 (rank : 197)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	118	Target Neighborhood Hits	453	Shared Neighborhood Hits	36
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

MCP_HUMAN
NC score	0.071212 (rank : 198)	θ value	θ > 10 (rank : 305)
Query Neighborhood Hits	118	Target Neighborhood Hits	82	Shared Neighborhood Hits	15
SwissProt Accessions	P15529, Q15429, Q53GV9, Q5HY94, Q5VWS6, Q5VWS7, Q5VWS8, Q5VWS9, Q5VWT0, Q5VWT1, Q5VWT2, Q6N0A1, Q7Z3R5, Q9NNW2, Q9NNW3, Q9NNW4	Gene names	CD46, MCP
Domain Architecture
Description	Membrane cofactor protein precursor (Trophoblast leukocyte common antigen) (TLX) (CD46 antigen).

VLDLR_HUMAN
NC score	0.070029 (rank : 199)	θ value	θ > 10 (rank : 396)
Query Neighborhood Hits	118	Target Neighborhood Hits	383	Shared Neighborhood Hits	38
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

FHR4_HUMAN
NC score	0.069425 (rank : 200)	θ value	θ > 10 (rank : 229)
Query Neighborhood Hits	118	Target Neighborhood Hits	75	Shared Neighborhood Hits	15
SwissProt Accessions	Q92496, Q9UJY6	Gene names	CFHL4, FHR4
Domain Architecture
Description	Complement factor H-related protein 4 precursor (FHR-4).

APOH_MOUSE
NC score	0.069363 (rank : 201)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	118	Target Neighborhood Hits	74	Shared Neighborhood Hits	13
SwissProt Accessions	Q01339	Gene names	Apoh, B2gp1
Domain Architecture
Description	Beta-2-glycoprotein 1 precursor (Beta-2-glycoprotein I) (Apolipoprotein H) (Apo-H) (B2GPI) (Beta(2)GPI) (Activated protein C- binding protein) (APC inhibitor).

TPA_MOUSE
NC score	0.069110 (rank : 202)	θ value	θ > 10 (rank : 379)
Query Neighborhood Hits	118	Target Neighborhood Hits	335	Shared Neighborhood Hits	24
SwissProt Accessions	P11214, Q91VP2	Gene names	Plat
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

VLDLR_MOUSE
NC score	0.069013 (rank : 203)	θ value	θ > 10 (rank : 397)
Query Neighborhood Hits	118	Target Neighborhood Hits	360	Shared Neighborhood Hits	39
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

THRB_HUMAN
NC score	0.068849 (rank : 204)	θ value	θ > 10 (rank : 355)
Query Neighborhood Hits	118	Target Neighborhood Hits	196	Shared Neighborhood Hits	16
SwissProt Accessions	P00734	Gene names	F2
Domain Architecture
Description	Prothrombin precursor (EC 3.4.21.5) (Coagulation factor II) [Contains: Activation peptide fragment 1; Activation peptide fragment 2; Thrombin light chain; Thrombin heavy chain].

TMPS2_HUMAN
NC score	0.068636 (rank : 205)	θ value	θ > 10 (rank : 361)
Query Neighborhood Hits	118	Target Neighborhood Hits	252	Shared Neighborhood Hits	27
SwissProt Accessions	O15393, Q9BXX1	Gene names	TMPRSS2, PRSS10
Domain Architecture
Description	Transmembrane protease, serine 2 precursor (EC 3.4.21.-) [Contains: Transmembrane protease, serine 2 non-catalytic chain; Transmembrane protease, serine 2 catalytic chain].

MATN4_HUMAN
NC score	0.068447 (rank : 206)	θ value	θ > 10 (rank : 302)
Query Neighborhood Hits	118	Target Neighborhood Hits	287	Shared Neighborhood Hits	28
SwissProt Accessions	O95460, Q5QPU2, Q5QPU3, Q5QPU4, Q8N2M5, Q8N2M7, Q9H1F8, Q9H1F9	Gene names	MATN4
Domain Architecture
Description	Matrilin-4 precursor.

MATN2_HUMAN
NC score	0.068321 (rank : 207)	θ value	θ > 10 (rank : 298)
Query Neighborhood Hits	118	Target Neighborhood Hits	365	Shared Neighborhood Hits	31
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

AGRIN_HUMAN
NC score	0.068180 (rank : 208)	θ value	θ > 10 (rank : 121)
Query Neighborhood Hits	118	Target Neighborhood Hits	582	Shared Neighborhood Hits	21
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

THRB_MOUSE
NC score	0.068032 (rank : 209)	θ value	θ > 10 (rank : 356)
Query Neighborhood Hits	118	Target Neighborhood Hits	195	Shared Neighborhood Hits	16
SwissProt Accessions	P19221	Gene names	F2, Cf2
Domain Architecture
Description	Prothrombin precursor (EC 3.4.21.5) (Coagulation factor II) [Contains: Activation peptide fragment 1; Activation peptide fragment 2; Thrombin light chain; Thrombin heavy chain].

DAF2_MOUSE
NC score	0.067624 (rank : 210)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	118	Target Neighborhood Hits	114	Shared Neighborhood Hits	15
SwissProt Accessions	Q61476	Gene names	Cd55b, Daf2
Domain Architecture
Description	Complement decay-accelerating factor transmembrane isoform precursor (DAF-TM) (CD55 antigen).

TMPS2_MOUSE
NC score	0.067539 (rank : 211)	θ value	θ > 10 (rank : 362)
Query Neighborhood Hits	118	Target Neighborhood Hits	243	Shared Neighborhood Hits	26
SwissProt Accessions	Q9JIQ8, Q9JKC4, Q9QY82	Gene names	Tmprss2
Domain Architecture
Description	Transmembrane protease, serine 2 (EC 3.4.21.-) (Epitheliasin) (Plasmic transmembrane protein X) [Contains: Transmembrane protease, serine 2 non-catalytic chain; Transmembrane protease, serine 2 catalytic chain].

DAF1_MOUSE
NC score	0.067455 (rank : 212)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	118	Target Neighborhood Hits	204	Shared Neighborhood Hits	17
SwissProt Accessions	Q61475, P97732, Q61397	Gene names	Cd55a, Daf1
Domain Architecture
Description	Complement decay-accelerating factor, GPI-anchored precursor (DAF-GPI) (CD55 antigen).

LRP4_MOUSE
NC score	0.066283 (rank : 213)	θ value	θ > 10 (rank : 274)
Query Neighborhood Hits	118	Target Neighborhood Hits	351	Shared Neighborhood Hits	38
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

MATN1_HUMAN
NC score	0.066123 (rank : 214)	θ value	θ > 10 (rank : 296)
Query Neighborhood Hits	118	Target Neighborhood Hits	191	Shared Neighborhood Hits	23
SwissProt Accessions	P21941	Gene names	MATN1, CMP, CRTM
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

MATN4_MOUSE
NC score	0.065832 (rank : 215)	θ value	θ > 10 (rank : 303)
Query Neighborhood Hits	118	Target Neighborhood Hits	277	Shared Neighborhood Hits	27
SwissProt Accessions	O89029, O89030, Q9QWS3	Gene names	Matn4
Domain Architecture
Description	Matrilin-4 precursor (MAT-4).

LRP4_HUMAN
NC score	0.065823 (rank : 216)	θ value	θ > 10 (rank : 273)
Query Neighborhood Hits	118	Target Neighborhood Hits	355	Shared Neighborhood Hits	38
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

TMPS9_HUMAN
NC score	0.064569 (rank : 217)	θ value	θ > 10 (rank : 373)
Query Neighborhood Hits	118	Target Neighborhood Hits	276	Shared Neighborhood Hits	25
SwissProt Accessions	Q7Z410, Q6ZND6, Q7Z411	Gene names	TMPRSS9
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 9 (EC 3.4.21.-) (Polyserase-1) (Polyserase-I) (Polyserine protease 1) [Contains: Serase-1; Serase-2; Serase-3].

ZAN_MOUSE
NC score	0.064400 (rank : 218)	θ value	θ > 10 (rank : 399)
Query Neighborhood Hits	118	Target Neighborhood Hits	808	Shared Neighborhood Hits	39
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

MEGF6_HUMAN
NC score	0.064202 (rank : 219)	θ value	θ > 10 (rank : 307)
Query Neighborhood Hits	118	Target Neighborhood Hits	671	Shared Neighborhood Hits	31
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

TM11D_HUMAN
NC score	0.063728 (rank : 220)	θ value	θ > 10 (rank : 357)
Query Neighborhood Hits	118	Target Neighborhood Hits	176	Shared Neighborhood Hits	14
SwissProt Accessions	O60235	Gene names	TMPRSS11D, HAT
Domain Architecture
Description	Transmembrane protease, serine 11D precursor (EC 3.4.21.-) (Airway trypsin-like protease) [Contains: Transmembrane protease, serine 11D non-catalytic chain; Transmembrane protease, serine 11D catalytic chain].

FBLN5_HUMAN
NC score	0.063682 (rank : 221)	θ value	θ > 10 (rank : 221)
Query Neighborhood Hits	118	Target Neighborhood Hits	329	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

MATN1_MOUSE
NC score	0.063680 (rank : 222)	θ value	θ > 10 (rank : 297)
Query Neighborhood Hits	118	Target Neighborhood Hits	186	Shared Neighborhood Hits	21
SwissProt Accessions	P51942	Gene names	Matn1, Cmp, Crtm
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

FBLN5_MOUSE
NC score	0.063487 (rank : 223)	θ value	θ > 10 (rank : 222)
Query Neighborhood Hits	118	Target Neighborhood Hits	317	Shared Neighborhood Hits	25
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

FBN1_HUMAN
NC score	0.063212 (rank : 224)	θ value	θ > 10 (rank : 223)
Query Neighborhood Hits	118	Target Neighborhood Hits	557	Shared Neighborhood Hits	39
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

TMPS3_HUMAN
NC score	0.063137 (rank : 225)	θ value	θ > 10 (rank : 363)
Query Neighborhood Hits	118	Target Neighborhood Hits	245	Shared Neighborhood Hits	24
SwissProt Accessions	P57727, Q6ZMC3	Gene names	TMPRSS3, ECHOS1, TADG12
Domain Architecture
Description	Transmembrane protease, serine 3 (EC 3.4.21.-) (Serine protease TADG- 12) (Tumor-associated differentially-expressed gene 12 protein).

HEPS_MOUSE
NC score	0.062946 (rank : 226)	θ value	θ > 10 (rank : 240)
Query Neighborhood Hits	118	Target Neighborhood Hits	178	Shared Neighborhood Hits	14
SwissProt Accessions	O35453, Q9CW97	Gene names	Hpn
Domain Architecture
Description	Serine protease hepsin (EC 3.4.21.-) [Contains: Serine protease hepsin non-catalytic chain; Serine protease hepsin catalytic chain].

TMSP8_MOUSE
NC score	0.062936 (rank : 227)	θ value	θ > 10 (rank : 377)
Query Neighborhood Hits	118	Target Neighborhood Hits	176	Shared Neighborhood Hits	14
SwissProt Accessions	Q9QYZ9, Q91XC4	Gene names	Tmprss8, Disp
Domain Architecture
Description	Transmembrane serine protease 8 precursor (EC 3.4.21.-) (Distal intestinal serine protease).

TM11D_MOUSE
NC score	0.062767 (rank : 228)	θ value	θ > 10 (rank : 358)
Query Neighborhood Hits	118	Target Neighborhood Hits	179	Shared Neighborhood Hits	14
SwissProt Accessions	Q8VHK8, Q7TNX3, Q8VDV1	Gene names	Tmprss11d, Mat
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 11D precursor (EC 3.4.21.-) (Airway trypsin-like protease) (AT) (Adrenal secretory serine protease) (AsP) [Contains: Transmembrane protease, serine 11D non-catalytic chain; Transmembrane protease, serine 11D catalytic chain].

F13B_MOUSE
NC score	0.062653 (rank : 229)	θ value	θ > 10 (rank : 205)
Query Neighborhood Hits	118	Target Neighborhood Hits	93	Shared Neighborhood Hits	14
SwissProt Accessions	Q07968	Gene names	F13b, Cf13b
Domain Architecture
Description	Coagulation factor XIII B chain precursor (Protein-glutamine gamma- glutamyltransferase B chain) (Transglutaminase B chain).

UROL1_MOUSE
NC score	0.062591 (rank : 230)	θ value	θ > 10 (rank : 393)
Query Neighborhood Hits	118	Target Neighborhood Hits	235	Shared Neighborhood Hits	19
SwissProt Accessions	Q5DID3, Q5DID1, Q5DID2	Gene names	Umodl1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

TM11E_MOUSE
NC score	0.062460 (rank : 231)	θ value	θ > 10 (rank : 360)
Query Neighborhood Hits	118	Target Neighborhood Hits	176	Shared Neighborhood Hits	14
SwissProt Accessions	Q5S248, Q8BM10	Gene names	Tmprss11e, Desc1
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 11E precursor (EC 3.4.21.-) (Serine protease DESC1) [Contains: Transmembrane protease, serine 11E non- catalytic chain; Transmembrane protease, serine 11E catalytic chain].

TMPS9_MOUSE
NC score	0.062427 (rank : 232)	θ value	θ > 10 (rank : 374)
Query Neighborhood Hits	118	Target Neighborhood Hits	296	Shared Neighborhood Hits	21
SwissProt Accessions	P69525	Gene names	Tmprss9
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 9 (EC 3.4.21.-) (Polyserase-1) (Polyserine protease 1) (Polyserase-I) [Contains: Serase-1; Serase-2; Serase-3].

TM11E_HUMAN
NC score	0.062380 (rank : 233)	θ value	θ > 10 (rank : 359)
Query Neighborhood Hits	118	Target Neighborhood Hits	181	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UL52, Q6UW31	Gene names	TMPRSS11E, DESC1
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 11E precursor (EC 3.4.21.-) (Serine protease DESC1) [Contains: Transmembrane protease, serine 11E non- catalytic chain; Transmembrane protease, serine 11E catalytic chain].

HEPS_HUMAN
NC score	0.062339 (rank : 234)	θ value	θ > 10 (rank : 239)
Query Neighborhood Hits	118	Target Neighborhood Hits	178	Shared Neighborhood Hits	14
SwissProt Accessions	P05981	Gene names	HPN, TMPRSS1
Domain Architecture
Description	Serine protease hepsin (EC 3.4.21.-) (Transmembrane protease, serine 1) [Contains: Serine protease hepsin non-catalytic chain; Serine protease hepsin catalytic chain].

CSPG3_MOUSE
NC score	0.062333 (rank : 235)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	118	Target Neighborhood Hits	657	Shared Neighborhood Hits	25
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

FBN3_HUMAN
NC score	0.062230 (rank : 236)	θ value	θ > 10 (rank : 227)
Query Neighborhood Hits	118	Target Neighborhood Hits	543	Shared Neighborhood Hits	39
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

FBN1_MOUSE
NC score	0.062107 (rank : 237)	θ value	θ > 10 (rank : 224)
Query Neighborhood Hits	118	Target Neighborhood Hits	563	Shared Neighborhood Hits	38
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

CD248_MOUSE
NC score	0.062019 (rank : 238)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	118	Target Neighborhood Hits	578	Shared Neighborhood Hits	33
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

TMPS4_MOUSE
NC score	0.061775 (rank : 239)	θ value	θ > 10 (rank : 366)
Query Neighborhood Hits	118	Target Neighborhood Hits	210	Shared Neighborhood Hits	21
SwissProt Accessions	Q8VCA5	Gene names	Tmprss4, Cap2
Domain Architecture
Description	Transmembrane protease, serine 4 (EC 3.4.21.-) (Channel-activating protease 2) (mCAP2).

DESC4_MOUSE
NC score	0.061570 (rank : 240)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	118	Target Neighborhood Hits	176	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BZ10, Q8BZ04	Gene names	Desc4
Domain Architecture	No domain graphic available
Description	Serine protease DESC4 precursor (EC 3.4.21.-) [Contains: Serine protease DESC4 non-catalytic chain; Serine protease DESC4 catalytic chain].

TRYG1_HUMAN
NC score	0.061522 (rank : 241)	θ value	θ > 10 (rank : 389)
Query Neighborhood Hits	118	Target Neighborhood Hits	179	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NRR2, Q96RZ8, Q9C015, Q9NRQ8, Q9UBB2	Gene names	TPSG1, TMT
Domain Architecture
Description	Tryptase gamma precursor (EC 3.4.21.-) (Transmembrane tryptase) [Contains: Tryptase gamma light chain; Tryptase gamma heavy chain].

TMPS3_MOUSE
NC score	0.061430 (rank : 242)	θ value	θ > 10 (rank : 364)
Query Neighborhood Hits	118	Target Neighborhood Hits	239	Shared Neighborhood Hits	21
SwissProt Accessions	Q8K1T0, Q8VDE0	Gene names	Tmprss3
Domain Architecture
Description	Transmembrane protease, serine 3 (EC 3.4.21.-).

TEST_MOUSE
NC score	0.061370 (rank : 243)	θ value	θ > 10 (rank : 354)
Query Neighborhood Hits	118	Target Neighborhood Hits	174	Shared Neighborhood Hits	14
SwissProt Accessions	Q9JHJ7, Q9DA14	Gene names	Prss21
Domain Architecture
Description	Testisin precursor (EC 3.4.21.-) (Tryptase 4).

CDCP1_MOUSE
NC score	0.061321 (rank : 244)	θ value	1.81305 (rank : 104)
Query Neighborhood Hits	118	Target Neighborhood Hits	32	Shared Neighborhood Hits	17
SwissProt Accessions	Q5U462, Q810J0, Q921M9	Gene names	Cdcp1
Domain Architecture	No domain graphic available
Description	CUB domain-containing protein 1 precursor (Transmembrane and associated with src kinases) (Membrane glycoprotein gp140) (CD318 antigen).

JAG2_HUMAN
NC score	0.061123 (rank : 245)	θ value	θ > 10 (rank : 248)
Query Neighborhood Hits	118	Target Neighborhood Hits	491	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

FA11_HUMAN
NC score	0.060966 (rank : 246)	θ value	θ > 10 (rank : 208)
Query Neighborhood Hits	118	Target Neighborhood Hits	178	Shared Neighborhood Hits	14
SwissProt Accessions	P03951, Q9Y495	Gene names	F11
Domain Architecture
Description	Coagulation factor XI precursor (EC 3.4.21.27) (Plasma thromboplastin antecedent) (PTA) (FXI) [Contains: Coagulation factor XIa heavy chain; Coagulation factor XIa light chain].

TMPSD_MOUSE
NC score	0.060811 (rank : 247)	θ value	θ > 10 (rank : 376)
Query Neighborhood Hits	118	Target Neighborhood Hits	334	Shared Neighborhood Hits	16
SwissProt Accessions	Q5U405, Q8CFE0, Q91VQ8	Gene names	Tmprss13, Msp
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).

FHR3_HUMAN
NC score	0.060796 (rank : 248)	θ value	θ > 10 (rank : 228)
Query Neighborhood Hits	118	Target Neighborhood Hits	74	Shared Neighborhood Hits	14
SwissProt Accessions	Q02985, Q9UJ16	Gene names	CFHL3, FHR3
Domain Architecture
Description	Complement factor H-related protein 3 precursor (FHR-3) (H factor-like protein 3) (DOWN16).

DLL1_MOUSE
NC score	0.060332 (rank : 249)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	118	Target Neighborhood Hits	456	Shared Neighborhood Hits	33
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

SUSD4_HUMAN
NC score	0.060320 (rank : 250)	θ value	θ > 10 (rank : 351)
Query Neighborhood Hits	118	Target Neighborhood Hits	88	Shared Neighborhood Hits	11
SwissProt Accessions	Q5VX71, Q6UX62, Q9BSR0, Q9NWG0	Gene names	SUSD4
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 4 precursor.

BSSP4_MOUSE
NC score	0.060316 (rank : 251)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	118	Target Neighborhood Hits	179	Shared Neighborhood Hits	14
SwissProt Accessions	Q9ER10	Gene names	Prss22, Bssp4, Prss26
Domain Architecture
Description	Brain-specific serine protease 4 precursor (EC 3.4.21.-) (BSSP-4) (Serine protease 22) (Tryptase epsilon).

TMPS4_HUMAN
NC score	0.060314 (rank : 252)	θ value	θ > 10 (rank : 365)
Query Neighborhood Hits	118	Target Neighborhood Hits	203	Shared Neighborhood Hits	15
SwissProt Accessions	Q9NRS4, Q5XKQ6, Q6UX37, Q9NZA5	Gene names	TMPRSS4, TMPRSS3
Domain Architecture
Description	Transmembrane protease, serine 4 (EC 3.4.21.-) (Membrane-type serine protease 2) (MT-SP2).

ACRO_MOUSE
NC score	0.060177 (rank : 253)	θ value	θ > 10 (rank : 120)
Query Neighborhood Hits	118	Target Neighborhood Hits	185	Shared Neighborhood Hits	14
SwissProt Accessions	P23578	Gene names	Acr
Domain Architecture
Description	Acrosin precursor (EC 3.4.21.10) [Contains: Acrosin light chain; Acrosin heavy chain].

TRYG1_MOUSE
NC score	0.060149 (rank : 254)	θ value	θ > 10 (rank : 390)
Query Neighborhood Hits	118	Target Neighborhood Hits	181	Shared Neighborhood Hits	14
SwissProt Accessions	Q9QUL7	Gene names	Tpsg1, Tmt
Domain Architecture
Description	Tryptase gamma precursor (EC 3.4.21.-) (Transmembrane tryptase) [Contains: Tryptase gamma light chain; Tryptase gamma heavy chain].

FBN2_MOUSE
NC score	0.059874 (rank : 255)	θ value	θ > 10 (rank : 226)
Query Neighborhood Hits	118	Target Neighborhood Hits	549	Shared Neighborhood Hits	38
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

KLKB1_MOUSE
NC score	0.059822 (rank : 256)	θ value	θ > 10 (rank : 264)
Query Neighborhood Hits	118	Target Neighborhood Hits	177	Shared Neighborhood Hits	14
SwissProt Accessions	P26262	Gene names	Klkb1, Klk3, Pk
Domain Architecture
Description	Plasma kallikrein precursor (EC 3.4.21.34) (Plasma prekallikrein) (Kininogenin) (Fletcher factor) [Contains: Plasma kallikrein heavy chain; Plasma kallikrein light chain].

TEST_HUMAN
NC score	0.059819 (rank : 257)	θ value	θ > 10 (rank : 353)
Query Neighborhood Hits	118	Target Neighborhood Hits	172	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y6M0, Q9NS34, Q9P2V6	Gene names	PRSS21, ESP1, TEST1
Domain Architecture
Description	Testisin precursor (EC 3.4.21.-) (Eosinophil serine protease 1) (ESP- 1).

C1QR1_HUMAN
NC score	0.059738 (rank : 258)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	118	Target Neighborhood Hits	493	Shared Neighborhood Hits	32
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

PRSS8_HUMAN
NC score	0.059679 (rank : 259)	θ value	θ > 10 (rank : 344)
Query Neighborhood Hits	118	Target Neighborhood Hits	177	Shared Neighborhood Hits	14
SwissProt Accessions	Q16651, Q9UCA3	Gene names	PRSS8
Domain Architecture
Description	Prostasin precursor (EC 3.4.21.-) [Contains: Prostasin light chain; Prostasin heavy chain].

PRS27_HUMAN
NC score	0.059637 (rank : 260)	θ value	θ > 10 (rank : 342)
Query Neighborhood Hits	118	Target Neighborhood Hits	177	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BQR3	Gene names	PRSS27, MPN
Domain Architecture
Description	Protease serine 27 precursor (EC 3.4.21.-) (Marapsin) (Pancreasin) (Channel-activating protease 2) (CAPH2).

PRSS8_MOUSE
NC score	0.059567 (rank : 261)	θ value	θ > 10 (rank : 345)
Query Neighborhood Hits	118	Target Neighborhood Hits	177	Shared Neighborhood Hits	14
SwissProt Accessions	Q9ESD1	Gene names	Prss8, Cap1
Domain Architecture
Description	Prostasin precursor (EC 3.4.21.-) (Channel-activating protease 1) [Contains: Prostasin light chain; Prostasin heavy chain].

BSSP4_HUMAN
NC score	0.059567 (rank : 262)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	118	Target Neighborhood Hits	176	Shared Neighborhood Hits	14
SwissProt Accessions	Q9GZN4, O43342, Q6UXE0	Gene names	PRSS22, BSSP4, PRSS26
Domain Architecture
Description	Brain-specific serine protease 4 precursor (EC 3.4.21.-) (BSSP-4) (Serine protease 22) (Tryptase epsilon).

LRP6_MOUSE
NC score	0.059526 (rank : 263)	θ value	θ > 10 (rank : 277)
Query Neighborhood Hits	118	Target Neighborhood Hits	232	Shared Neighborhood Hits	38
SwissProt Accessions	O88572	Gene names	Lrp6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

DLL1_HUMAN
NC score	0.059456 (rank : 264)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	118	Target Neighborhood Hits	455	Shared Neighborhood Hits	33
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

FA11_MOUSE
NC score	0.059418 (rank : 265)	θ value	θ > 10 (rank : 209)
Query Neighborhood Hits	118	Target Neighborhood Hits	180	Shared Neighborhood Hits	14
SwissProt Accessions	Q91Y47	Gene names	F11
Domain Architecture
Description	Coagulation factor XI precursor (EC 3.4.21.27) (Plasma thromboplastin antecedent) (PTA) (FXI) [Contains: Coagulation factor XIa heavy chain; Coagulation factor XIa light chain].

ACRO_HUMAN
NC score	0.059372 (rank : 266)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	118	Target Neighborhood Hits	291	Shared Neighborhood Hits	16
SwissProt Accessions	P10323, Q6ICK2	Gene names	ACR, ACRS
Domain Architecture
Description	Acrosin precursor (EC 3.4.21.10) [Contains: Acrosin light chain; Acrosin heavy chain].

PRS27_MOUSE
NC score	0.059296 (rank : 267)	θ value	θ > 10 (rank : 343)
Query Neighborhood Hits	118	Target Neighborhood Hits	175	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BJR6	Gene names	Prss27, Mpn
Domain Architecture	No domain graphic available
Description	Protease serine 27 precursor (EC 3.4.21.-) (Marapsin) (Pancreasin).

FBN2_HUMAN
NC score	0.059276 (rank : 268)	θ value	θ > 10 (rank : 225)
Query Neighborhood Hits	118	Target Neighborhood Hits	560	Shared Neighborhood Hits	36
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

JAG1_HUMAN
NC score	0.059159 (rank : 269)	θ value	θ > 10 (rank : 246)
Query Neighborhood Hits	118	Target Neighborhood Hits	514	Shared Neighborhood Hits	38
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

TMPSD_HUMAN
NC score	0.059137 (rank : 270)	θ value	θ > 10 (rank : 375)
Query Neighborhood Hits	118	Target Neighborhood Hits	333	Shared Neighborhood Hits	17
SwissProt Accessions	Q9BYE2, Q86YM4, Q96JY8, Q9BYE1	Gene names	TMPRSS13, MSP, TMPRSS11
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).

ZAN_HUMAN
NC score	0.059069 (rank : 271)	θ value	θ > 10 (rank : 398)
Query Neighborhood Hits	118	Target Neighborhood Hits	679	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

CLCR_HUMAN
NC score	0.059025 (rank : 272)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	118	Target Neighborhood Hits	177	Shared Neighborhood Hits	14
SwissProt Accessions	Q99895, O00765, Q9NUH5	Gene names	CTRC, CLCR
Domain Architecture
Description	Caldecrin precursor (EC 3.4.21.2) (Chymotrypsin C).

KLKB1_HUMAN
NC score	0.059001 (rank : 273)	θ value	θ > 10 (rank : 263)
Query Neighborhood Hits	118	Target Neighborhood Hits	183	Shared Neighborhood Hits	14
SwissProt Accessions	P03952	Gene names	KLKB1, KLK3
Domain Architecture
Description	Plasma kallikrein precursor (EC 3.4.21.34) (Plasma prekallikrein) (Kininogenin) (Fletcher factor) [Contains: Plasma kallikrein heavy chain; Plasma kallikrein light chain].

LRP6_HUMAN
NC score	0.058988 (rank : 274)	θ value	θ > 10 (rank : 276)
Query Neighborhood Hits	118	Target Neighborhood Hits	235	Shared Neighborhood Hits	37
SwissProt Accessions	O75581	Gene names	LRP6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

CSPG3_HUMAN
NC score	0.058812 (rank : 275)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	118	Target Neighborhood Hits	676	Shared Neighborhood Hits	24
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

LTBP3_MOUSE
NC score	0.058738 (rank : 276)	θ value	θ > 10 (rank : 287)
Query Neighborhood Hits	118	Target Neighborhood Hits	475	Shared Neighborhood Hits	33
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

JAG2_MOUSE
NC score	0.058569 (rank : 277)	θ value	θ > 10 (rank : 249)
Query Neighborhood Hits	118	Target Neighborhood Hits	504	Shared Neighborhood Hits	31
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

CSPG2_MOUSE
NC score	0.058560 (rank : 278)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	118	Target Neighborhood Hits	711	Shared Neighborhood Hits	26
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

PLMN_MOUSE
NC score	0.058552 (rank : 279)	θ value	θ > 10 (rank : 333)
Query Neighborhood Hits	118	Target Neighborhood Hits	208	Shared Neighborhood Hits	16
SwissProt Accessions	P20918, Q8CIS2, Q91WJ5	Gene names	Plg
Domain Architecture
Description	Plasminogen precursor (EC 3.4.21.7) [Contains: Plasmin heavy chain A; Activation peptide; Angiostatin; Plasmin heavy chain A, short form; Plasmin light chain B].

CSPG2_HUMAN
NC score	0.058460 (rank : 280)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	118	Target Neighborhood Hits	681	Shared Neighborhood Hits	29
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

JAG1_MOUSE
NC score	0.058409 (rank : 281)	θ value	θ > 10 (rank : 247)
Query Neighborhood Hits	118	Target Neighborhood Hits	518	Shared Neighborhood Hits	36
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

CTRL_HUMAN
NC score	0.058363 (rank : 282)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	118	Target Neighborhood Hits	179	Shared Neighborhood Hits	14
SwissProt Accessions	P40313	Gene names	CTRL, CTRL1
Domain Architecture
Description	Chymotrypsin-like protease CTRL-1 precursor (EC 3.4.21.-).

LYAM1_MOUSE
NC score	0.058245 (rank : 283)	θ value	θ > 10 (rank : 289)
Query Neighborhood Hits	118	Target Neighborhood Hits	332	Shared Neighborhood Hits	29
SwissProt Accessions	P18337	Gene names	Sell, Lnhr, Ly-22
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Lymphocyte antigen 22) (Ly-22) (Lymphocyte surface MEL-14 antigen) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

FBLN1_HUMAN
NC score	0.058225 (rank : 284)	θ value	θ > 10 (rank : 214)
Query Neighborhood Hits	118	Target Neighborhood Hits	324	Shared Neighborhood Hits	29
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

PGBM_MOUSE
NC score	0.058223 (rank : 285)	θ value	θ > 10 (rank : 331)
Query Neighborhood Hits	118	Target Neighborhood Hits	1073	Shared Neighborhood Hits	37
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

TRYB1_MOUSE
NC score	0.057947 (rank : 286)	θ value	θ > 10 (rank : 386)
Query Neighborhood Hits	118	Target Neighborhood Hits	175	Shared Neighborhood Hits	14
SwissProt Accessions	Q02844	Gene names	Tpsab1, Mcpt7
Domain Architecture
Description	Tryptase precursor (EC 3.4.21.59) (Mast cell protease 7) (MMCP-7) (Tryptase alpha/beta-1).

POLS2_MOUSE
NC score	0.057930 (rank : 287)	θ value	θ > 10 (rank : 335)
Query Neighborhood Hits	118	Target Neighborhood Hits	188	Shared Neighborhood Hits	14
SwissProt Accessions	Q5K2P8	Gene names	Prss36
Domain Architecture	No domain graphic available
Description	Polyserase-2 precursor (EC 3.4.21.-) (Polyserine protease 2) (Protease serine 36).

POLS2_HUMAN
NC score	0.057744 (rank : 288)	θ value	θ > 10 (rank : 334)
Query Neighborhood Hits	118	Target Neighborhood Hits	192	Shared Neighborhood Hits	14
SwissProt Accessions	Q5K4E3, Q8NBY4	Gene names	PRSS36
Domain Architecture	No domain graphic available
Description	Polyserase-2 precursor (EC 3.4.21.-) (Polyserine protease 2) (Protease serine 36).

UROK_HUMAN
NC score	0.057735 (rank : 289)	θ value	θ > 10 (rank : 391)
Query Neighborhood Hits	118	Target Neighborhood Hits	272	Shared Neighborhood Hits	21
SwissProt Accessions	P00749, Q15844, Q16618, Q969W6	Gene names	PLAU
Domain Architecture
Description	Urokinase-type plasminogen activator precursor (EC 3.4.21.73) (uPA) (U-plasminogen activator) [Contains: Urokinase-type plasminogen activator long chain A; Urokinase-type plasminogen activator short chain A; Urokinase-type plasminogen activator chain B].

EGF_MOUSE
NC score	0.057579 (rank : 290)	θ value	θ > 10 (rank : 200)
Query Neighborhood Hits	118	Target Neighborhood Hits	358	Shared Neighborhood Hits	27
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

NOTC1_MOUSE
NC score	0.057522 (rank : 291)	θ value	θ > 10 (rank : 316)
Query Neighborhood Hits	118	Target Neighborhood Hits	916	Shared Neighborhood Hits	40
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

TMPS5_MOUSE
NC score	0.057457 (rank : 292)	θ value	θ > 10 (rank : 368)
Query Neighborhood Hits	118	Target Neighborhood Hits	185	Shared Neighborhood Hits	15
SwissProt Accessions	Q9ER04, Q9ER02, Q9ER03	Gene names	Tmprss5
Domain Architecture
Description	Transmembrane protease, serine 5 (EC 3.4.21.-) (Spinesin).

TMPS5_HUMAN
NC score	0.057418 (rank : 293)	θ value	θ > 10 (rank : 367)
Query Neighborhood Hits	118	Target Neighborhood Hits	181	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H3S3	Gene names	TMPRSS5
Domain Architecture
Description	Transmembrane protease, serine 5 (EC 3.4.21.-) (Spinesin).

NOTC2_MOUSE
NC score	0.057161 (rank : 294)	θ value	θ > 10 (rank : 318)
Query Neighborhood Hits	118	Target Neighborhood Hits	1069	Shared Neighborhood Hits	44
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

PLMN_HUMAN
NC score	0.057075 (rank : 295)	θ value	θ > 10 (rank : 332)
Query Neighborhood Hits	118	Target Neighborhood Hits	204	Shared Neighborhood Hits	16
SwissProt Accessions	P00747, Q15146, Q6PA00	Gene names	PLG
Domain Architecture
Description	Plasminogen precursor (EC 3.4.21.7) [Contains: Plasmin heavy chain A; Activation peptide; Angiostatin; Plasmin heavy chain A, short form; Plasmin light chain B].

FBLN2_HUMAN
NC score	0.057020 (rank : 296)	θ value	θ > 10 (rank : 216)
Query Neighborhood Hits	118	Target Neighborhood Hits	392	Shared Neighborhood Hits	26
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

MCPT6_MOUSE
NC score	0.056898 (rank : 297)	θ value	θ > 10 (rank : 304)
Query Neighborhood Hits	118	Target Neighborhood Hits	175	Shared Neighborhood Hits	14
SwissProt Accessions	P21845, Q61962	Gene names	Mcpt6
Domain Architecture
Description	Mast cell protease 6 precursor (EC 3.4.21.59) (MMCP-6) (Tryptase).

FHR5_HUMAN
NC score	0.056866 (rank : 298)	θ value	θ > 10 (rank : 230)
Query Neighborhood Hits	118	Target Neighborhood Hits	77	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BXR6	Gene names	CFHL5, FHR5
Domain Architecture
Description	Complement factor H-related protein 5 precursor (FHR-5).

UROK_MOUSE
NC score	0.056760 (rank : 299)	θ value	θ > 10 (rank : 392)
Query Neighborhood Hits	118	Target Neighborhood Hits	273	Shared Neighborhood Hits	21
SwissProt Accessions	P06869	Gene names	Plau
Domain Architecture
Description	Urokinase-type plasminogen activator precursor (EC 3.4.21.73) (uPA) (U-plasminogen activator) [Contains: Urokinase-type plasminogen activator long chain A; Urokinase-type plasminogen activator short chain A; Urokinase-type plasminogen activator chain B].

TRYB1_HUMAN
NC score	0.056629 (rank : 300)	θ value	θ > 10 (rank : 385)
Query Neighborhood Hits	118	Target Neighborhood Hits	175	Shared Neighborhood Hits	14
SwissProt Accessions	Q15661, Q15663, Q9H2Y4	Gene names	TPSAB1, TPSB1
Domain Architecture
Description	Tryptase beta-1 precursor (EC 3.4.21.59) (Tryptase-1) (Tryptase I).

TRYB2_HUMAN
NC score	0.056629 (rank : 301)	θ value	θ > 10 (rank : 387)
Query Neighborhood Hits	118	Target Neighborhood Hits	175	Shared Neighborhood Hits	14
SwissProt Accessions	P20231, O95827, Q15664, Q9UQI6, Q9UQI7	Gene names	TPSB2, TPS2
Domain Architecture
Description	Tryptase beta-2 precursor (EC 3.4.21.59) (Tryptase-2) (Tryptase II).

UROM_HUMAN
NC score	0.056471 (rank : 302)	θ value	θ > 10 (rank : 394)
Query Neighborhood Hits	118	Target Neighborhood Hits	284	Shared Neighborhood Hits	24
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

CD248_HUMAN
NC score	0.056372 (rank : 303)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	118	Target Neighborhood Hits	679	Shared Neighborhood Hits	31
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

ELA2A_MOUSE
NC score	0.056335 (rank : 304)	θ value	θ > 10 (rank : 202)
Query Neighborhood Hits	118	Target Neighborhood Hits	178	Shared Neighborhood Hits	14
SwissProt Accessions	P05208	Gene names	Ela2a, Ela-2, Ela2
Domain Architecture
Description	Elastase-2A precursor (EC 3.4.21.71) (Elastase-2).

CTRB1_HUMAN
NC score	0.056280 (rank : 305)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	118	Target Neighborhood Hits	176	Shared Neighborhood Hits	14
SwissProt Accessions	P17538	Gene names	CTRB1, CTRB
Domain Architecture
Description	Chymotrypsinogen B precursor (EC 3.4.21.1) [Contains: Chymotrypsin B chain A; Chymotrypsin B chain B; Chymotrypsin B chain C].

CO6_HUMAN
NC score	0.056265 (rank : 306)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	118	Target Neighborhood Hits	331	Shared Neighborhood Hits	30
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

SUSD4_MOUSE
NC score	0.056168 (rank : 307)	θ value	θ > 10 (rank : 352)
Query Neighborhood Hits	118	Target Neighborhood Hits	122	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BH32, Q8VC43	Gene names	Susd4
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 4 precursor.

TRY2_HUMAN
NC score	0.056162 (rank : 308)	θ value	θ > 10 (rank : 381)
Query Neighborhood Hits	118	Target Neighborhood Hits	175	Shared Neighborhood Hits	14
SwissProt Accessions	P07478	Gene names	PRSS2, TRY2, TRYP2
Domain Architecture
Description	Trypsin-2 precursor (EC 3.4.21.4) (Trypsin II) (Anionic trypsinogen).

NOTC1_HUMAN
NC score	0.055937 (rank : 309)	θ value	θ > 10 (rank : 315)
Query Neighborhood Hits	118	Target Neighborhood Hits	906	Shared Neighborhood Hits	39
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

ELA2A_HUMAN
NC score	0.055815 (rank : 310)	θ value	θ > 10 (rank : 201)
Query Neighborhood Hits	118	Target Neighborhood Hits	180	Shared Neighborhood Hits	14
SwissProt Accessions	P08217, Q14243	Gene names	ELA2A
Domain Architecture
Description	Elastase-2A precursor (EC 3.4.21.71).

UROM_MOUSE
NC score	0.055752 (rank : 311)	θ value	θ > 10 (rank : 395)
Query Neighborhood Hits	118	Target Neighborhood Hits	276	Shared Neighborhood Hits	19
SwissProt Accessions	Q91X17, Q3TN64, Q3TP60, Q62285	Gene names	Umod
Domain Architecture	No domain graphic available
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

DLK_HUMAN
NC score	0.055631 (rank : 312)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	118	Target Neighborhood Hits	401	Shared Neighborhood Hits	23
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

NOTC2_HUMAN
NC score	0.055571 (rank : 313)	θ value	θ > 10 (rank : 317)
Query Neighborhood Hits	118	Target Neighborhood Hits	1113	Shared Neighborhood Hits	42
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

LTB1S_HUMAN
NC score	0.055567 (rank : 314)	θ value	θ > 10 (rank : 282)
Query Neighborhood Hits	118	Target Neighborhood Hits	502	Shared Neighborhood Hits	35
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTBP2_MOUSE
NC score	0.055513 (rank : 315)	θ value	θ > 10 (rank : 285)
Query Neighborhood Hits	118	Target Neighborhood Hits	617	Shared Neighborhood Hits	39
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

TRYA1_HUMAN
NC score	0.055439 (rank : 316)	θ value	θ > 10 (rank : 384)
Query Neighborhood Hits	118	Target Neighborhood Hits	177	Shared Neighborhood Hits	14
SwissProt Accessions	P15157, Q9H2Y5, Q9UQI1	Gene names	TPSAB1, TPS1
Domain Architecture
Description	Tryptase alpha-1 precursor (EC 3.4.21.59) (Tryptase-1).

LTB1L_HUMAN
NC score	0.055425 (rank : 317)	θ value	θ > 10 (rank : 280)
Query Neighborhood Hits	118	Target Neighborhood Hits	553	Shared Neighborhood Hits	35
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_MOUSE
NC score	0.055389 (rank : 318)	θ value	θ > 10 (rank : 283)
Query Neighborhood Hits	118	Target Neighborhood Hits	479	Shared Neighborhood Hits	36
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

CD320_HUMAN
NC score	0.055347 (rank : 319)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	118	Target Neighborhood Hits	103	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NPF0, Q53HF7	Gene names	CD320, 8D6A
Domain Architecture	No domain graphic available
Description	CD320 antigen precursor (8D6 antigen) (FDC-signaling molecule 8D6) (FDC-SM-8D6).

DLL3_MOUSE
NC score	0.055263 (rank : 320)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	118	Target Neighborhood Hits	399	Shared Neighborhood Hits	21
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

EGFL7_MOUSE
NC score	0.055236 (rank : 321)	θ value	θ > 10 (rank : 196)
Query Neighborhood Hits	118	Target Neighborhood Hits	287	Shared Neighborhood Hits	19
SwissProt Accessions	Q9QXT5, Q6XD35, Q9DCP5	Gene names	Egfl7, Megf7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (Zneu1).

APOA_HUMAN
NC score	0.055086 (rank : 322)	θ value	θ > 10 (rank : 122)
Query Neighborhood Hits	118	Target Neighborhood Hits	221	Shared Neighborhood Hits	16
SwissProt Accessions	P08519	Gene names	LPA
Domain Architecture
Description	Apolipoprotein(a) precursor (EC 3.4.21.-) (Apo(a)) (Lp(a)).

SHBG_HUMAN
NC score	0.055083 (rank : 323)	θ value	θ > 10 (rank : 346)
Query Neighborhood Hits	118	Target Neighborhood Hits	45	Shared Neighborhood Hits	7
SwissProt Accessions	P04278, P14689, Q16616	Gene names	SHBG
Domain Architecture
Description	Sex hormone-binding globulin precursor (SHBG) (Sex steroid-binding protein) (SBP) (Testis-specific androgen-binding protein) (ABP) (Testosterone-estrogen-binding globulin) (Testosterone-estradiol- binding globulin) (TeBG).

LTB1L_MOUSE
NC score	0.055066 (rank : 324)	θ value	θ > 10 (rank : 281)
Query Neighborhood Hits	118	Target Neighborhood Hits	514	Shared Neighborhood Hits	36
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

TRY2_MOUSE
NC score	0.055012 (rank : 325)	θ value	θ > 10 (rank : 382)
Query Neighborhood Hits	118	Target Neighborhood Hits	174	Shared Neighborhood Hits	14
SwissProt Accessions	P07146	Gene names	Prss2, Try2
Domain Architecture
Description	Anionic trypsin-2 precursor (EC 3.4.21.4) (Anionic trypsin II) (Pretrypsinogen II).

DLK_MOUSE
NC score	0.054981 (rank : 326)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	118	Target Neighborhood Hits	374	Shared Neighborhood Hits	19
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

KLK6_HUMAN
NC score	0.054919 (rank : 327)	θ value	θ > 10 (rank : 259)
Query Neighborhood Hits	118	Target Neighborhood Hits	175	Shared Neighborhood Hits	14
SwissProt Accessions	Q92876	Gene names	KLK6, PRSS18, PRSS9
Domain Architecture
Description	Kallikrein-6 precursor (EC 3.4.21.-) (Protease M) (Neurosin) (Zyme) (SP59).

TRYD_HUMAN
NC score	0.054859 (rank : 328)	θ value	θ > 10 (rank : 388)
Query Neighborhood Hits	118	Target Neighborhood Hits	175	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BZJ3, O95824, Q8TDI6, Q96L36, Q96RZ5, Q9H2Y6, Q9UQI8	Gene names	TPSD1
Domain Architecture
Description	Tryptase delta precursor (EC 3.4.21.59) (Delta tryptase) (Mast cell mMCP-7-like) (Tryptase-3) (HmMCP-3-like tryptase III).

DLL3_HUMAN
NC score	0.054834 (rank : 329)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	118	Target Neighborhood Hits	419	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

FBLN2_MOUSE
NC score	0.054746 (rank : 330)	θ value	θ > 10 (rank : 217)
Query Neighborhood Hits	118	Target Neighborhood Hits	505	Shared Neighborhood Hits	27
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

TRY1_HUMAN
NC score	0.054691 (rank : 331)	θ value	θ > 10 (rank : 380)
Query Neighborhood Hits	118	Target Neighborhood Hits	176	Shared Neighborhood Hits	14
SwissProt Accessions	P07477, Q92955, Q9HAN4, Q9HAN5, Q9HAN6, Q9HAN7	Gene names	PRSS1, TRP1, TRY1, TRYP1
Domain Architecture
Description	Trypsin-1 precursor (EC 3.4.21.4) (Trypsin I) (Cationic trypsinogen).

F13B_HUMAN
NC score	0.054657 (rank : 332)	θ value	θ > 10 (rank : 204)
Query Neighborhood Hits	118	Target Neighborhood Hits	84	Shared Neighborhood Hits	13
SwissProt Accessions	P05160	Gene names	F13B
Domain Architecture
Description	Coagulation factor XIII B chain precursor (Protein-glutamine gamma- glutamyltransferase B chain) (Transglutaminase B chain) (Fibrin- stabilizing factor B subunit).

STAB1_HUMAN
NC score	0.054368 (rank : 333)	θ value	θ > 10 (rank : 347)
Query Neighborhood Hits	118	Target Neighborhood Hits	546	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

ELA2B_HUMAN
NC score	0.054306 (rank : 334)	θ value	θ > 10 (rank : 203)
Query Neighborhood Hits	118	Target Neighborhood Hits	178	Shared Neighborhood Hits	14
SwissProt Accessions	P08218	Gene names	ELA2B
Domain Architecture
Description	Elastase-2B precursor (EC 3.4.21.71).

TRY3_HUMAN
NC score	0.054236 (rank : 335)	θ value	θ > 10 (rank : 383)
Query Neighborhood Hits	118	Target Neighborhood Hits	178	Shared Neighborhood Hits	14
SwissProt Accessions	P35030, P15951, Q15665, Q9UQV3	Gene names	PRSS3, PRSS4, TRY3, TRY4
Domain Architecture
Description	Trypsin-3 precursor (EC 3.4.21.4) (Trypsin III) (Brain trypsinogen) (Mesotrypsinogen) (Trypsin IV).

PGBM_HUMAN
NC score	0.054140 (rank : 336)	θ value	θ > 10 (rank : 330)
Query Neighborhood Hits	118	Target Neighborhood Hits	1113	Shared Neighborhood Hits	34
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

STAB1_MOUSE
NC score	0.053950 (rank : 337)	θ value	θ > 10 (rank : 348)
Query Neighborhood Hits	118	Target Neighborhood Hits	566	Shared Neighborhood Hits	24
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

MATN3_HUMAN
NC score	0.053939 (rank : 338)	θ value	θ > 10 (rank : 300)
Query Neighborhood Hits	118	Target Neighborhood Hits	268	Shared Neighborhood Hits	26
SwissProt Accessions	O15232	Gene names	MATN3
Domain Architecture
Description	Matrilin-3 precursor.

KLK14_HUMAN
NC score	0.053754 (rank : 339)	θ value	θ > 10 (rank : 256)
Query Neighborhood Hits	118	Target Neighborhood Hits	179	Shared Neighborhood Hits	14
SwissProt Accessions	Q9P0G3	Gene names	KLK14, KLKL6
Domain Architecture
Description	Kallikrein-14 precursor (EC 3.4.21.-) (Kallikrein-like protein 6) (KLK-L6).

NRPN_HUMAN
NC score	0.053680 (rank : 340)	θ value	θ > 10 (rank : 322)
Query Neighborhood Hits	118	Target Neighborhood Hits	182	Shared Neighborhood Hits	14
SwissProt Accessions	O60259, Q9HCB3, Q9UIL9, Q9UQ47	Gene names	KLK8, NRPN, PRSS19, TADG14
Domain Architecture
Description	Neuropsin precursor (EC 3.4.21.-) (NP) (Kallikrein-8) (Ovasin) (Serine protease TADG-14) (Tumor-associated differentially expressed gene 14 protein).

NOTC3_MOUSE
NC score	0.053673 (rank : 341)	θ value	θ > 10 (rank : 320)
Query Neighborhood Hits	118	Target Neighborhood Hits	975	Shared Neighborhood Hits	44
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

FBLN1_MOUSE
NC score	0.053502 (rank : 342)	θ value	θ > 10 (rank : 215)
Query Neighborhood Hits	118	Target Neighborhood Hits	329	Shared Neighborhood Hits	26
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

LYAM1_HUMAN
NC score	0.053499 (rank : 343)	θ value	θ > 10 (rank : 288)
Query Neighborhood Hits	118	Target Neighborhood Hits	315	Shared Neighborhood Hits	25
SwissProt Accessions	P14151, P15023	Gene names	SELL, LNHR, LYAM1
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Leukocyte surface antigen Leu-8) (TQ1) (gp90-MEL) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

FBLN3_HUMAN
NC score	0.053085 (rank : 344)	θ value	θ > 10 (rank : 218)
Query Neighborhood Hits	118	Target Neighborhood Hits	293	Shared Neighborhood Hits	25
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

LTBP3_HUMAN
NC score	0.053082 (rank : 345)	θ value	θ > 10 (rank : 286)
Query Neighborhood Hits	118	Target Neighborhood Hits	502	Shared Neighborhood Hits	35
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

LTBP2_HUMAN
NC score	0.052927 (rank : 346)	θ value	θ > 10 (rank : 284)
Query Neighborhood Hits	118	Target Neighborhood Hits	552	Shared Neighborhood Hits	35
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

GRAH_HUMAN
NC score	0.052880 (rank : 347)	θ value	θ > 10 (rank : 234)
Query Neighborhood Hits	118	Target Neighborhood Hits	175	Shared Neighborhood Hits	14
SwissProt Accessions	P20718	Gene names	GZMH, CGL2, CTSGL2
Domain Architecture
Description	Granzyme H precursor (EC 3.4.21.-) (Cytotoxic T-lymphocyte proteinase) (Cathepsin G-like 2) (CTSGL2) (CCP-X) (Cytotoxic serine protease C) (CSP-C).

CFAD_MOUSE
NC score	0.052806 (rank : 348)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	118	Target Neighborhood Hits	177	Shared Neighborhood Hits	14
SwissProt Accessions	P03953, Q61280	Gene names	Cfd, Adn, Df
Domain Architecture
Description	Complement factor D precursor (EC 3.4.21.46) (C3 convertase activator) (Properdin factor D) (Adipsin) (28 kDa adipocyte protein).

NOTC3_HUMAN
NC score	0.052782 (rank : 349)	θ value	θ > 10 (rank : 319)
Query Neighborhood Hits	118	Target Neighborhood Hits	1062	Shared Neighborhood Hits	39
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

FBLN4_HUMAN
NC score	0.052601 (rank : 350)	θ value	θ > 10 (rank : 219)
Query Neighborhood Hits	118	Target Neighborhood Hits	278	Shared Neighborhood Hits	23
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

CFAD_HUMAN
NC score	0.052546 (rank : 351)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	118	Target Neighborhood Hits	176	Shared Neighborhood Hits	14
SwissProt Accessions	P00746	Gene names	CFD, DF
Domain Architecture
Description	Complement factor D precursor (EC 3.4.21.46) (C3 convertase activator) (Properdin factor D) (Adipsin).

KLK12_HUMAN
NC score	0.052422 (rank : 352)	θ value	θ > 10 (rank : 254)
Query Neighborhood Hits	118	Target Neighborhood Hits	197	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UKR0, Q9UKR1	Gene names	KLK12, KLKL5
Domain Architecture
Description	Kallikrein-12 precursor (EC 3.4.21.-) (Kallikrein-like protein 5) (KLK-L5).

KLK7_MOUSE
NC score	0.052304 (rank : 353)	θ value	θ > 10 (rank : 261)
Query Neighborhood Hits	118	Target Neighborhood Hits	175	Shared Neighborhood Hits	14
SwissProt Accessions	Q91VE3, Q9R048	Gene names	Klk7, Prss6, Scce
Domain Architecture	No domain graphic available
Description	Kallikrein-7 precursor (EC 3.4.21.-) (Stratum corneum chymotryptic enzyme) (Thymopsin).

MATN3_MOUSE
NC score	0.052259 (rank : 354)	θ value	θ > 10 (rank : 301)
Query Neighborhood Hits	118	Target Neighborhood Hits	261	Shared Neighborhood Hits	25
SwissProt Accessions	O35701, Q9JHM0	Gene names	Matn3
Domain Architecture
Description	Matrilin-3 precursor.

KLK10_HUMAN
NC score	0.052213 (rank : 355)	θ value	θ > 10 (rank : 252)
Query Neighborhood Hits	118	Target Neighborhood Hits	178	Shared Neighborhood Hits	15
SwissProt Accessions	O43240, Q99920, Q9GZW9	Gene names	KLK10, NES1, PRRSL1
Domain Architecture
Description	Kallikrein-10 precursor (EC 3.4.21.-) (Protease serine-like 1) (Normal epithelial cell-specific 1).

KLK13_HUMAN
NC score	0.052208 (rank : 356)	θ value	θ > 10 (rank : 255)
Query Neighborhood Hits	118	Target Neighborhood Hits	179	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UKR3, Q9Y433	Gene names	KLK13, KLKL4
Domain Architecture
Description	Kallikrein-13 precursor (EC 3.4.21.-) (Kallikrein-like protein 4) (KLK-L4).

DNER_HUMAN
NC score	0.052191 (rank : 357)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	118	Target Neighborhood Hits	460	Shared Neighborhood Hits	25
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

PAPPA_MOUSE
NC score	0.052095 (rank : 358)	θ value	θ > 10 (rank : 328)
Query Neighborhood Hits	118	Target Neighborhood Hits	153	Shared Neighborhood Hits	13
SwissProt Accessions	Q8R4K8, Q80VW3, Q80YY1, Q8K423, Q8R4K7, Q9ES06, Q9JK57	Gene names	Pappa
Domain Architecture	No domain graphic available
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

NRPN_MOUSE
NC score	0.052058 (rank : 359)	θ value	θ > 10 (rank : 323)
Query Neighborhood Hits	118	Target Neighborhood Hits	186	Shared Neighborhood Hits	14
SwissProt Accessions	Q61955	Gene names	Klk8, Nrpn, Prss19
Domain Architecture
Description	Neuropsin precursor (EC 3.4.21.-) (NP) (Kallikrein-8).

DNER_MOUSE
NC score	0.051969 (rank : 360)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	118	Target Neighborhood Hits	413	Shared Neighborhood Hits	24
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

CATG_MOUSE
NC score	0.051821 (rank : 361)	θ value	θ > 10 (rank : 137)
Query Neighborhood Hits	118	Target Neighborhood Hits	174	Shared Neighborhood Hits	14
SwissProt Accessions	P28293	Gene names	Ctsg
Domain Architecture
Description	Cathepsin G precursor (EC 3.4.21.20) (Vimentin-specific protease) (VSP).

KLK11_HUMAN
NC score	0.051782 (rank : 362)	θ value	θ > 10 (rank : 253)
Query Neighborhood Hits	118	Target Neighborhood Hits	174	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UBX7, O75837, Q9NS65	Gene names	KLK11, PRSS20, TLSP
Domain Architecture
Description	Kallikrein-11 precursor (EC 3.4.21.-) (Hippostasin) (Trypsin-like protease).

K1KB9_MOUSE
NC score	0.051672 (rank : 363)	θ value	θ > 10 (rank : 251)
Query Neighborhood Hits	118	Target Neighborhood Hits	176	Shared Neighborhood Hits	14
SwissProt Accessions	P15949	Gene names	Klk1b9, Egfbp3, Klk-9, Klk9
Domain Architecture
Description	Kallikrein 1-related peptidase b9 precursor (EC 3.4.21.35) (Tissue kallikrein-9) (Glandular kallikrein K9) (mGK-9) (Epidermal growth factor-binding protein type C) (EGF-BP C).

KLK7_HUMAN
NC score	0.051638 (rank : 364)	θ value	θ > 10 (rank : 260)
Query Neighborhood Hits	118	Target Neighborhood Hits	175	Shared Neighborhood Hits	14
SwissProt Accessions	P49862, Q8N5N9, Q8NFV7	Gene names	KLK7, PRSS6, SCCE
Domain Architecture
Description	Kallikrein-7 precursor (EC 3.4.21.-) (hK7) (Stratum corneum chymotryptic enzyme) (hSCCE).

EGFL9_MOUSE
NC score	0.051589 (rank : 365)	θ value	θ > 10 (rank : 199)
Query Neighborhood Hits	118	Target Neighborhood Hits	379	Shared Neighborhood Hits	22
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

DLL4_HUMAN
NC score	0.051545 (rank : 366)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	118	Target Neighborhood Hits	435	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

DLL4_MOUSE
NC score	0.051529 (rank : 367)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	118	Target Neighborhood Hits	440	Shared Neighborhood Hits	26
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

NID2_MOUSE
NC score	0.051472 (rank : 368)	θ value	θ > 10 (rank : 314)
Query Neighborhood Hits	118	Target Neighborhood Hits	338	Shared Neighborhood Hits	33
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

NOTC4_MOUSE
NC score	0.051420 (rank : 369)	θ value	θ > 10 (rank : 321)
Query Neighborhood Hits	118	Target Neighborhood Hits	872	Shared Neighborhood Hits	38
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

FBLN4_MOUSE
NC score	0.051302 (rank : 370)	θ value	θ > 10 (rank : 220)
Query Neighborhood Hits	118	Target Neighborhood Hits	270	Shared Neighborhood Hits	23
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

C163B_HUMAN
NC score	0.051266 (rank : 371)	θ value	θ > 10 (rank : 131)
Query Neighborhood Hits	118	Target Neighborhood Hits	64	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NR16, Q6UWC2	Gene names	CD163L1, CD163B, M160
Domain Architecture	No domain graphic available
Description	Scavenger receptor cysteine-rich type 1 protein M160 precursor (CD163 antigen-like 1) (CD163b antigen).

C163A_MOUSE
NC score	0.051228 (rank : 372)	θ value	θ > 10 (rank : 130)
Query Neighborhood Hits	118	Target Neighborhood Hits	48	Shared Neighborhood Hits	5
SwissProt Accessions	Q2VLH6, Q2VLH5, Q99MX8	Gene names	Cd163, M130
Domain Architecture	No domain graphic available
Description	Scavenger receptor cysteine-rich type 1 protein M130 precursor (CD163 antigen) [Contains: Soluble CD163 (sCD163)].

K1KB1_MOUSE
NC score	0.051044 (rank : 373)	θ value	θ > 10 (rank : 250)
Query Neighborhood Hits	118	Target Neighborhood Hits	180	Shared Neighborhood Hits	16
SwissProt Accessions	P00755	Gene names	Klk1b1, Klk-1, Klk1
Domain Architecture
Description	Kallikrein 1-related peptidase b1 precursor (EC 3.4.21.35) (Glandular kallikrein K1) (Tissue kallikrein-1) (mGK-1).

KLK1_MOUSE
NC score	0.050896 (rank : 374)	θ value	θ > 10 (rank : 258)
Query Neighborhood Hits	118	Target Neighborhood Hits	179	Shared Neighborhood Hits	14
SwissProt Accessions	P15947, Q61855	Gene names	Klk1, Klk-6, Klk6
Domain Architecture
Description	Glandular kallikrein K1 precursor (EC 3.4.21.35) (Tissue kallikrein-6) (mGK-6) (Renal kallikrein) (KAL-B).

ZP2_HUMAN
NC score	0.050860 (rank : 375)	θ value	θ > 10 (rank : 400)
Query Neighborhood Hits	118	Target Neighborhood Hits	26	Shared Neighborhood Hits	4
SwissProt Accessions	Q05996	Gene names	ZP2, ZPA
Domain Architecture
Description	Zona pellucida sperm-binding protein 2 precursor (Zona pellucida glycoprotein ZP2) (Zona pellucida protein A).

LRP5_HUMAN
NC score	0.050684 (rank : 376)	θ value	θ > 10 (rank : 275)
Query Neighborhood Hits	118	Target Neighborhood Hits	224	Shared Neighborhood Hits	32
SwissProt Accessions	O75197, Q96TD6, Q9UP66	Gene names	LRP5, LRP7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor.

C163A_HUMAN
NC score	0.050585 (rank : 377)	θ value	θ > 10 (rank : 129)
Query Neighborhood Hits	118	Target Neighborhood Hits	54	Shared Neighborhood Hits	5
SwissProt Accessions	Q86VB7, Q07898, Q07899, Q07900, Q07901, Q2VLH7	Gene names	CD163, M130
Domain Architecture	No domain graphic available
Description	Scavenger receptor cysteine-rich type 1 protein M130 precursor (CD163 antigen) (Hemoglobin scavenger receptor) [Contains: Soluble CD163 (sCD163)].

SUSD2_HUMAN
NC score	0.050523 (rank : 378)	θ value	θ > 10 (rank : 350)
Query Neighborhood Hits	118	Target Neighborhood Hits	99	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UGT4, Q9H5Y6	Gene names	SUSD2
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 2 precursor.

KLK9_HUMAN
NC score	0.050457 (rank : 379)	θ value	θ > 10 (rank : 262)
Query Neighborhood Hits	118	Target Neighborhood Hits	176	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UKQ9	Gene names	KLK9
Domain Architecture
Description	Kallikrein-9 precursor (EC 3.4.21.-) (Kallikrein-like protein 3) (KLK- L3).

KLK15_HUMAN
NC score	0.050342 (rank : 380)	θ value	θ > 10 (rank : 257)
Query Neighborhood Hits	118	Target Neighborhood Hits	180	Shared Neighborhood Hits	14
SwissProt Accessions	Q9H2R5, Q15358, Q9H2R3, Q9H2R4, Q9H2R6, Q9HBG9	Gene names	KLK15
Domain Architecture
Description	Kallikrein-15 precursor (EC 3.4.21.-) (ACO protease).

CD97_HUMAN
NC score	0.050016 (rank : 381)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	118	Target Neighborhood Hits	353	Shared Neighborhood Hits	27
SwissProt Accessions	P48960, O00718, O76101, Q8NG72, Q8TBQ7	Gene names	CD97
Domain Architecture
Description	CD97 antigen precursor (Leukocyte antigen CD97).

PHF22_HUMAN
NC score	0.031842 (rank : 382)	θ value	0.125558 (rank : 92)
Query Neighborhood Hits	118	Target Neighborhood Hits	121	Shared Neighborhood Hits	3
SwissProt Accessions	Q96CB8, Q9HD71	Gene names	INTS12, PHF22
Domain Architecture	No domain graphic available
Description	Integrator complex subunit 12 (PHD finger protein 22).

SDC4_HUMAN
NC score	0.027841 (rank : 383)	θ value	1.38821 (rank : 102)
Query Neighborhood Hits	118	Target Neighborhood Hits	22	Shared Neighborhood Hits	4
SwissProt Accessions	P31431, O00773, Q16833	Gene names	SDC4
Domain Architecture
Description	Syndecan-4 precursor (SYND4) (Amphiglycan) (Ryudocan core protein).

AP180_HUMAN
NC score	0.019789 (rank : 384)	θ value	1.81305 (rank : 103)
Query Neighborhood Hits	118	Target Neighborhood Hits	183	Shared Neighborhood Hits	5
SwissProt Accessions	O60641, Q5JX13, Q68DL9, Q6P9D3, Q9NTY7	Gene names	SNAP91, KIAA0656
Domain Architecture
Description	Clathrin coat assembly protein AP180 (Clathrin coat-associated protein AP180) (91 kDa synaptosomal-associated protein).

AP180_MOUSE
NC score	0.018215 (rank : 385)	θ value	2.36792 (rank : 106)
Query Neighborhood Hits	118	Target Neighborhood Hits	194	Shared Neighborhood Hits	6
SwissProt Accessions	Q61548, Q61547	Gene names	Snap91
Domain Architecture
Description	Clathrin coat assembly protein AP180 (Clathrin coat-associated protein AP180) (91 kDa synaptosomal-associated protein) (Phosphoprotein F1- 20).

SYNPO_MOUSE
NC score	0.017844 (rank : 386)	θ value	0.62314 (rank : 94)
Query Neighborhood Hits	118	Target Neighborhood Hits	242	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CC35, Q99JI0	Gene names	Synpo, Kiaa1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

SDC3_MOUSE
NC score	0.017592 (rank : 387)	θ value	6.88961 (rank : 115)
Query Neighborhood Hits	118	Target Neighborhood Hits	107	Shared Neighborhood Hits	6
SwissProt Accessions	Q64519, Q3UDD9, Q6ZQA4, Q7TQD4	Gene names	Sdc3, Kiaa0468
Domain Architecture
Description	Syndecan-3 precursor (SYND3).

IPO4_HUMAN
NC score	0.017045 (rank : 388)	θ value	4.03905 (rank : 110)
Query Neighborhood Hits	118	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TEX9, Q86TZ9, Q8NCG8, Q96SJ3, Q9BTI4, Q9H5L0	Gene names	IPO4, IMP4B, RANBP4
Domain Architecture
Description	Importin-4 (Importin 4b) (Imp4b) (Ran-binding protein 4) (RanBP4).

MYCB2_HUMAN
NC score	0.015520 (rank : 389)	θ value	0.365318 (rank : 93)
Query Neighborhood Hits	118	Target Neighborhood Hits	390	Shared Neighborhood Hits	2
SwissProt Accessions	O75592, Q5JSX8, Q5VZN6, Q6PIB6, Q9UQ11, Q9Y6E4	Gene names	MYCBP2, KIAA0916, PAM
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

MOGT2_MOUSE
NC score	0.010059 (rank : 390)	θ value	1.38821 (rank : 100)
Query Neighborhood Hits	118	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q80W94	Gene names	Mogat2, Dgat2l5, Mgat1l
Domain Architecture	No domain graphic available
Description	2-acylglycerol O-acyltransferase 2 (EC 2.3.1.22) (Monoacylglycerol O- acyltransferase 2) (Acyl CoA:monoacylglycerol acyltransferase 2) (MGAT2) (Diacylglycerol acyltransferase 2-like protein 5) (Monoacylglycerol O-acyltransferase 1-like).

CJ047_MOUSE
NC score	0.009415 (rank : 391)	θ value	6.88961 (rank : 112)
Query Neighborhood Hits	118	Target Neighborhood Hits	76	Shared Neighborhood Hits	2
SwissProt Accessions	Q8C5R2, Q8R017, Q8R2Z9	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf47 homolog.

TIP_HUMAN
NC score	0.007189 (rank : 392)	θ value	8.99809 (rank : 118)
Query Neighborhood Hits	118	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TB96, Q96SR4, Q9BRE2, Q9H2V9	Gene names	ITFG1, TIP
Domain Architecture	No domain graphic available
Description	T-cell immunomodulatory protein precursor (Protein TIP) (Integrin alpha FG-GAP repeat-containing protein 1).

FMN2_HUMAN
NC score	0.006436 (rank : 393)	θ value	1.81305 (rank : 105)
Query Neighborhood Hits	118	Target Neighborhood Hits	484	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

PLS1_HUMAN
NC score	0.005418 (rank : 394)	θ value	6.88961 (rank : 114)
Query Neighborhood Hits	118	Target Neighborhood Hits	35	Shared Neighborhood Hits	3
SwissProt Accessions	O15162	Gene names	PLSCR1
Domain Architecture
Description	Phospholipid scramblase 1 (PL scramblase 1) (Ca(2+)-dependent phospholipid scramblase 1) (Erythrocyte phospholipid scramblase) (MmTRA1b).

DICER_MOUSE
NC score	0.004803 (rank : 395)	θ value	6.88961 (rank : 113)
Query Neighborhood Hits	118	Target Neighborhood Hits	140	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R418	Gene names	Dicer1, Dicer, Mdcr
Domain Architecture
Description	Endoribonuclease Dicer (EC 3.1.26.-) (Double-strand-specific ribonuclease mDCR-1).

EMSY_HUMAN
NC score	0.004346 (rank : 396)	θ value	8.99809 (rank : 117)
Query Neighborhood Hits	118	Target Neighborhood Hits	296	Shared Neighborhood Hits	7
SwissProt Accessions	Q7Z589, Q4G109, Q8NBU6, Q8TE50, Q9H8I9, Q9NRH0	Gene names	EMSY, C11orf30
Domain Architecture
Description	Protein EMSY.

OXRP_HUMAN
NC score	0.003613 (rank : 397)	θ value	3.0926 (rank : 108)
Query Neighborhood Hits	118	Target Neighborhood Hits	544	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y4L1	Gene names	HYOU1, ORP150
Domain Architecture
Description	150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia up- regulated 1).

TITIN_HUMAN
NC score	-0.002358 (rank : 398)	θ value	5.27518 (rank : 111)
Query Neighborhood Hits	118	Target Neighborhood Hits	2923	Shared Neighborhood Hits	13
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

SP4_MOUSE
NC score	-0.004268 (rank : 399)	θ value	3.0926 (rank : 109)
Query Neighborhood Hits	118	Target Neighborhood Hits	759	Shared Neighborhood Hits	5
SwissProt Accessions	Q62445	Gene names	Sp4
Domain Architecture
Description	Transcription factor Sp4.

SP4_HUMAN
NC score	-0.004737 (rank : 400)	θ value	6.88961 (rank : 116)
Query Neighborhood Hits	118	Target Neighborhood Hits	749	Shared Neighborhood Hits	5
SwissProt Accessions	Q02446, O60402	Gene names	SP4
Domain Architecture
Description	Transcription factor Sp4 (SPR-1).

EGR1_HUMAN
NC score	-0.005175 (rank : 401)	θ value	3.0926 (rank : 107)
Query Neighborhood Hits	118	Target Neighborhood Hits	788	Shared Neighborhood Hits	4
SwissProt Accessions	P18146	Gene names	EGR1, ZNF225
Domain Architecture
Description	Early growth response protein 1 (EGR-1) (Krox-24 protein) (Transcription factor Zif268) (Nerve growth factor-induced protein A) (NGFI-A) (Transcription factor ETR103) (Zinc finger protein 225) (AT225).