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Network neighborhood for query Sequence : FA8_HUMAN

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FA8_HUMAN
SwissProt Accessions	P00451	Gene names	F8, F8C
Domain Architecture
Description	Coagulation factor VIII precursor (Procoagulant component) (Antihemophilic factor) (AHF) [Contains: Factor VIIIa heavy chain, 200 kDa isoform; Factor VIIIa heavy chain, 92 kDa isoform; Factor VIII B chain; Factor VIIIa light chain].
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

FA8_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	112	Target Neighborhood Hits	112	Shared Neighborhood Hits	112
SwissProt Accessions	P00451	Gene names	F8, F8C
Domain Architecture
Description	Coagulation factor VIII precursor (Procoagulant component) (Antihemophilic factor) (AHF) [Contains: Factor VIIIa heavy chain, 200 kDa isoform; Factor VIIIa heavy chain, 92 kDa isoform; Factor VIII B chain; Factor VIIIa light chain].

FA8_MOUSE
θ value	0 (rank : 2)	NC score	0.989977 (rank : 2)
Query Neighborhood Hits	112	Target Neighborhood Hits	100	Shared Neighborhood Hits	46
SwissProt Accessions	Q06194	Gene names	F8, Cf8, F8c
Domain Architecture
Description	Coagulation factor VIII precursor (Procoagulant component).

FA5_HUMAN
θ value	1.46868e-151 (rank : 3)	NC score	0.931033 (rank : 3)
Query Neighborhood Hits	112	Target Neighborhood Hits	172	Shared Neighborhood Hits	39
SwissProt Accessions	P12259, Q14285, Q6UPU6	Gene names	F5
Domain Architecture
Description	Coagulation factor V precursor (Activated protein C cofactor) [Contains: Coagulation factor V heavy chain; Coagulation factor V light chain].

HEPH_MOUSE
θ value	5.8157e-124 (rank : 4)	NC score	0.698293 (rank : 7)
Query Neighborhood Hits	112	Target Neighborhood Hits	17	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Z0Z4, Q6ZQ65, Q80Y80, Q8C4S2	Gene names	Heph, Kiaa0698
Domain Architecture	No domain graphic available
Description	Hephaestin precursor (EC 1.-.-.-).

CERU_HUMAN
θ value	2.52853e-119 (rank : 5)	NC score	0.696921 (rank : 8)
Query Neighborhood Hits	112	Target Neighborhood Hits	15	Shared Neighborhood Hits	7
SwissProt Accessions	P00450, Q14063, Q2PP18, Q9UKS4	Gene names	CP
Domain Architecture
Description	Ceruloplasmin precursor (EC 1.16.3.1) (Ferroxidase).

HEPH_HUMAN
θ value	2.00348e-116 (rank : 6)	NC score	0.695653 (rank : 9)
Query Neighborhood Hits	112	Target Neighborhood Hits	19	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BQS7, O75180, Q6UW45, Q9C058	Gene names	HEPH, KIAA0698
Domain Architecture	No domain graphic available
Description	Hephaestin precursor (EC 1.-.-.-).

CERU_MOUSE
θ value	1.02895e-112 (rank : 7)	NC score	0.694526 (rank : 10)
Query Neighborhood Hits	112	Target Neighborhood Hits	23	Shared Neighborhood Hits	7
SwissProt Accessions	Q61147	Gene names	Cp
Domain Architecture
Description	Ceruloplasmin precursor (EC 1.16.3.1) (Ferroxidase).

MFGM_MOUSE
θ value	5.91091e-68 (rank : 8)	NC score	0.666429 (rank : 11)
Query Neighborhood Hits	112	Target Neighborhood Hits	233	Shared Neighborhood Hits	32
SwissProt Accessions	P21956, P97800, Q3TBN5, Q9R1X9, Q9WTS3	Gene names	Mfge8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (MFGM) (Sperm surface protein SP47) (MP47).

EDIL3_HUMAN
θ value	1.00825e-67 (rank : 9)	NC score	0.550544 (rank : 15)
Query Neighborhood Hits	112	Target Neighborhood Hits	292	Shared Neighborhood Hits	32
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

EDIL3_MOUSE
θ value	6.53529e-67 (rank : 10)	NC score	0.541861 (rank : 16)
Query Neighborhood Hits	112	Target Neighborhood Hits	317	Shared Neighborhood Hits	32
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

MFGM_HUMAN
θ value	8.55514e-59 (rank : 11)	NC score	0.766309 (rank : 4)
Query Neighborhood Hits	112	Target Neighborhood Hits	150	Shared Neighborhood Hits	32
SwissProt Accessions	Q08431	Gene names	MFGE8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (HMFG) (Breast epithelial antigen BA46) (MFGM) [Contains: Lactadherin short form; Medin].

NRP1_MOUSE
θ value	3.61106e-41 (rank : 12)	NC score	0.533166 (rank : 19)
Query Neighborhood Hits	112	Target Neighborhood Hits	120	Shared Neighborhood Hits	31
SwissProt Accessions	P97333	Gene names	Nrp1, Nrp
Domain Architecture
Description	Neuropilin-1 precursor (A5 protein).

NRP2_HUMAN
θ value	2.34062e-40 (rank : 13)	NC score	0.537143 (rank : 18)
Query Neighborhood Hits	112	Target Neighborhood Hits	120	Shared Neighborhood Hits	32
SwissProt Accessions	O60462, O14820, O14821	Gene names	NRP2, VEGF165R2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

NRP2_MOUSE
θ value	3.99248e-40 (rank : 14)	NC score	0.539580 (rank : 17)
Query Neighborhood Hits	112	Target Neighborhood Hits	113	Shared Neighborhood Hits	32
SwissProt Accessions	O35375, O35373, O35374, O35376, O35377, O35378	Gene names	Nrp2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

NRP1_HUMAN
θ value	3.37985e-39 (rank : 15)	NC score	0.530262 (rank : 20)
Query Neighborhood Hits	112	Target Neighborhood Hits	119	Shared Neighborhood Hits	32
SwissProt Accessions	O14786, O60461, Q96IH5	Gene names	NRP1, NRP, VEGF165R
Domain Architecture
Description	Neuropilin-1 precursor (Vascular endothelial cell growth factor 165 receptor) (CD304 antigen).

DCBD2_HUMAN
θ value	3.87602e-27 (rank : 16)	NC score	0.576457 (rank : 14)
Query Neighborhood Hits	112	Target Neighborhood Hits	118	Shared Neighborhood Hits	33
SwissProt Accessions	Q96PD2, Q8N6M4, Q8TDX2	Gene names	DCBLD2, CLCP1, ESDN
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein) (CUB, LCCL and coagulation factor V/VIII-homology domains protein 1).

DCBD2_MOUSE
θ value	2.12685e-25 (rank : 17)	NC score	0.588061 (rank : 12)
Query Neighborhood Hits	112	Target Neighborhood Hits	113	Shared Neighborhood Hits	32
SwissProt Accessions	Q91ZV3, Q8BKI4	Gene names	Dcbld2, Esdn
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein).

DCBD1_HUMAN
θ value	4.01107e-24 (rank : 18)	NC score	0.588013 (rank : 13)
Query Neighborhood Hits	112	Target Neighborhood Hits	110	Shared Neighborhood Hits	33
SwissProt Accessions	Q8N8Z6, Q5H992, Q8IYK5, Q8N7L9, Q96NH2	Gene names	DCBLD1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

CPXM2_MOUSE
θ value	4.9032e-22 (rank : 19)	NC score	0.481624 (rank : 21)
Query Neighborhood Hits	112	Target Neighborhood Hits	58	Shared Neighborhood Hits	31
SwissProt Accessions	Q9D2L5, O54860, Q8VDQ4	Gene names	Cpxm2, Cpx2
Domain Architecture
Description	Carboxypeptidase-like protein X2 precursor.

CPXM2_HUMAN
θ value	1.86321e-21 (rank : 20)	NC score	0.478823 (rank : 22)
Query Neighborhood Hits	112	Target Neighborhood Hits	84	Shared Neighborhood Hits	31
SwissProt Accessions	Q8N436	Gene names	CPXM2
Domain Architecture
Description	Carboxypeptidase-like protein X2 precursor.

XLRS1_MOUSE
θ value	3.51386e-20 (rank : 21)	NC score	0.729240 (rank : 5)
Query Neighborhood Hits	112	Target Neighborhood Hits	32	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Z1L4	Gene names	Rs1, Rs1h, Xlrs1
Domain Architecture
Description	Retinoschisin precursor (X-linked juvenile retinoschisis protein homolog).

XLRS1_HUMAN
θ value	1.02238e-19 (rank : 22)	NC score	0.728464 (rank : 6)
Query Neighborhood Hits	112	Target Neighborhood Hits	32	Shared Neighborhood Hits	31
SwissProt Accessions	O15537	Gene names	RS1, XLRS1
Domain Architecture
Description	Retinoschisin precursor (X-linked juvenile retinoschisis protein).

CNTP2_HUMAN
θ value	4.02038e-16 (rank : 23)	NC score	0.463066 (rank : 23)
Query Neighborhood Hits	112	Target Neighborhood Hits	199	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UHC6, Q52LV1, Q5H9Q7, Q9UQ12	Gene names	CNTNAP2, CASPR2, KIAA0868
Domain Architecture
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

CPXM1_MOUSE
θ value	4.02038e-16 (rank : 24)	NC score	0.434363 (rank : 29)
Query Neighborhood Hits	112	Target Neighborhood Hits	63	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Z100, Q99LA3	Gene names	Cpxm1, Cpx1, Cpxm
Domain Architecture
Description	Probable carboxypeptidase X1 precursor (EC 3.4.17.-) (Metallocarboxypeptidase CPX-1).

CPXM1_HUMAN
θ value	1.16975e-15 (rank : 25)	NC score	0.442074 (rank : 28)
Query Neighborhood Hits	112	Target Neighborhood Hits	69	Shared Neighborhood Hits	32
SwissProt Accessions	Q96SM3, Q6P4G8, Q6UW65, Q9NUB5	Gene names	CPXM1, CPX1, CPXM
Domain Architecture
Description	Probable carboxypeptidase X1 precursor (EC 3.4.17.-) (Metallocarboxypeptidase CPX-1).

CNTP4_MOUSE
θ value	2.60593e-15 (rank : 26)	NC score	0.446204 (rank : 26)
Query Neighborhood Hits	112	Target Neighborhood Hits	193	Shared Neighborhood Hits	31
SwissProt Accessions	Q99P47	Gene names	Cntnap4, Caspr4
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

CNTP4_HUMAN
θ value	5.8054e-15 (rank : 27)	NC score	0.443397 (rank : 27)
Query Neighborhood Hits	112	Target Neighborhood Hits	187	Shared Neighborhood Hits	31
SwissProt Accessions	Q9C0A0	Gene names	CNTNAP4, CASPR4, KIAA1763
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

CNTP2_MOUSE
θ value	7.58209e-15 (rank : 28)	NC score	0.450711 (rank : 25)
Query Neighborhood Hits	112	Target Neighborhood Hits	194	Shared Neighborhood Hits	31
SwissProt Accessions	Q9CPW0, Q6P2K4, Q6ZQ31	Gene names	Cntnap2, Kiaa0868
Domain Architecture	No domain graphic available
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

CNTP3_HUMAN
θ value	1.09485e-13 (rank : 29)	NC score	0.453587 (rank : 24)
Query Neighborhood Hits	112	Target Neighborhood Hits	195	Shared Neighborhood Hits	32
SwissProt Accessions	Q9BZ76, Q9C0E9	Gene names	CNTNAP3, CASPR3, KIAA1714
Domain Architecture
Description	Contactin-associated protein-like 3 precursor (Cell recognition molecule Caspr3).

DDR2_MOUSE
θ value	2.43908e-13 (rank : 30)	NC score	0.164178 (rank : 32)
Query Neighborhood Hits	112	Target Neighborhood Hits	813	Shared Neighborhood Hits	33
SwissProt Accessions	Q62371	Gene names	Ddr2, Ntrkr3, Tkt, Tyro10
Domain Architecture
Description	Discoidin domain-containing receptor 2 precursor (EC 2.7.10.1) (Discoidin domain receptor 2) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO 10) (Neurotrophic tyrosine kinase, receptor-related 3) (CD167b antigen).

DDR1_HUMAN
θ value	5.43371e-13 (rank : 31)	NC score	0.150869 (rank : 35)
Query Neighborhood Hits	112	Target Neighborhood Hits	819	Shared Neighborhood Hits	33
SwissProt Accessions	Q08345, Q14196, Q16562, Q5ST12, Q9UD37	Gene names	DDR1, CAK, EDDR1, RTK6, TRKE
Domain Architecture
Description	Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (TRK E) (Protein-tyrosine kinase RTK 6) (HGK2) (CD167a antigen).

CNTP1_HUMAN
θ value	6.00763e-12 (rank : 32)	NC score	0.421300 (rank : 30)
Query Neighborhood Hits	112	Target Neighborhood Hits	196	Shared Neighborhood Hits	32
SwissProt Accessions	P78357	Gene names	CNTNAP1, CASPR, NRXN4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (p190).

DDR1_MOUSE
θ value	6.00763e-12 (rank : 33)	NC score	0.143975 (rank : 36)
Query Neighborhood Hits	112	Target Neighborhood Hits	818	Shared Neighborhood Hits	33
SwissProt Accessions	Q03146	Gene names	Ddr1, Cak, Eddr1, Mpk6
Domain Architecture
Description	Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (Protein-tyrosine kinase MPK-6) (CD167a antigen).

DDR2_HUMAN
θ value	7.84624e-12 (rank : 34)	NC score	0.162424 (rank : 33)
Query Neighborhood Hits	112	Target Neighborhood Hits	818	Shared Neighborhood Hits	33
SwissProt Accessions	Q16832	Gene names	DDR2, NTRKR3, TKT, TYRO10
Domain Architecture
Description	Discoidin domain-containing receptor 2 precursor (EC 2.7.10.1) (Discoidin domain receptor 2) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO 10) (Neurotrophic tyrosine kinase, receptor-related 3) (CD167b antigen).

CNTP1_MOUSE
θ value	6.64225e-11 (rank : 35)	NC score	0.419184 (rank : 31)
Query Neighborhood Hits	112	Target Neighborhood Hits	183	Shared Neighborhood Hits	32
SwissProt Accessions	O54991	Gene names	Cntnap1, Nrxn4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (Paranodin) (NCP1) (MHDNIV).

CALB2_MOUSE
θ value	0.0330416 (rank : 36)	NC score	0.047764 (rank : 95)
Query Neighborhood Hits	112	Target Neighborhood Hits	141	Shared Neighborhood Hits	5
SwissProt Accessions	Q08331, Q60964, Q9JM81	Gene names	Calb2
Domain Architecture
Description	Calretinin (CR).

GCC2_HUMAN
θ value	0.0330416 (rank : 37)	NC score	0.017174 (rank : 118)
Query Neighborhood Hits	112	Target Neighborhood Hits	1558	Shared Neighborhood Hits	26
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

RBP24_HUMAN
θ value	0.0330416 (rank : 38)	NC score	0.017167 (rank : 119)
Query Neighborhood Hits	112	Target Neighborhood Hits	1559	Shared Neighborhood Hits	26
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

ZN281_HUMAN
θ value	0.0330416 (rank : 39)	NC score	0.002639 (rank : 160)
Query Neighborhood Hits	112	Target Neighborhood Hits	745	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y2X9, Q9NY92	Gene names	ZNF281, GZP1, ZBP99
Domain Architecture	No domain graphic available
Description	Zinc finger protein 281 (Zinc finger DNA-binding protein 99) (Transcription factor ZBP-99) (GC-box-binding zinc finger protein 1).

CALB2_HUMAN
θ value	0.0431538 (rank : 40)	NC score	0.046698 (rank : 97)
Query Neighborhood Hits	112	Target Neighborhood Hits	149	Shared Neighborhood Hits	5
SwissProt Accessions	P22676, Q53HD2, Q96BK4	Gene names	CALB2, CAB29
Domain Architecture
Description	Calretinin (CR) (29 kDa calbindin).

TM117_MOUSE
θ value	0.0431538 (rank : 41)	NC score	0.056292 (rank : 83)
Query Neighborhood Hits	112	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BH18, Q8C6X8	Gene names	Tmem117
Domain Architecture	No domain graphic available
Description	Transmembrane protein 117.

BORG2_MOUSE
θ value	0.0563607 (rank : 42)	NC score	0.050387 (rank : 93)
Query Neighborhood Hits	112	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CQC5, Q3UD77, Q8BVR7	Gene names	Cdc42ep3, Borg2, Cep3
Domain Architecture	No domain graphic available
Description	Cdc42 effector protein 3 (Binder of Rho GTPases 2).

BORG2_HUMAN
θ value	0.0736092 (rank : 43)	NC score	0.049593 (rank : 94)
Query Neighborhood Hits	112	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UKI2, O95353, Q9UQJ0	Gene names	CDC42EP3, BORG2, CEP3
Domain Architecture	No domain graphic available
Description	Cdc42 effector protein 3 (Binder of Rho GTPases 2) (MSE55-related Cdc42-binding protein).

SSPO_MOUSE
θ value	0.0736092 (rank : 44)	NC score	0.047021 (rank : 96)
Query Neighborhood Hits	112	Target Neighborhood Hits	800	Shared Neighborhood Hits	19
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

K0319_MOUSE
θ value	0.163984 (rank : 45)	NC score	0.028602 (rank : 99)
Query Neighborhood Hits	112	Target Neighborhood Hits	134	Shared Neighborhood Hits	5
SwissProt Accessions	Q5SZV5, Q80U39	Gene names	Kiaa0319
Domain Architecture	No domain graphic available
Description	Protein KIAA0319 precursor.

TOP2B_HUMAN
θ value	0.163984 (rank : 46)	NC score	0.020983 (rank : 107)
Query Neighborhood Hits	112	Target Neighborhood Hits	101	Shared Neighborhood Hits	7
SwissProt Accessions	Q02880, Q13600, Q9UMG8, Q9UQP8	Gene names	TOP2B
Domain Architecture
Description	DNA topoisomerase 2-beta (EC 5.99.1.3) (DNA topoisomerase II, beta isozyme).

MAP4_MOUSE
θ value	0.21417 (rank : 47)	NC score	0.021624 (rank : 104)
Query Neighborhood Hits	112	Target Neighborhood Hits	409	Shared Neighborhood Hits	9
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

RTN4_HUMAN
θ value	0.21417 (rank : 48)	NC score	0.022523 (rank : 103)
Query Neighborhood Hits	112	Target Neighborhood Hits	357	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NQC3, O94962, Q9BXG5, Q9H212, Q9H3I3, Q9UQ42, Q9Y293, Q9Y2Y7, Q9Y5U6	Gene names	RTN4, KIAA0886, NOGO
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein) (Foocen) (Neuroendocrine-specific protein) (NSP) (Neuroendocrine-specific protein C homolog) (RTN-x) (Reticulon-5).

RBBP6_HUMAN
θ value	0.365318 (rank : 49)	NC score	0.015000 (rank : 125)
Query Neighborhood Hits	112	Target Neighborhood Hits	1135	Shared Neighborhood Hits	22
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

RBM16_HUMAN
θ value	0.47712 (rank : 50)	NC score	0.025709 (rank : 101)
Query Neighborhood Hits	112	Target Neighborhood Hits	300	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UPN6, Q5TBU6, Q9BQN8, Q9BX43	Gene names	RBM16, KIAA1116
Domain Architecture
Description	Putative RNA-binding protein 16 (RNA-binding motif protein 16).

TTP_MOUSE
θ value	0.62314 (rank : 51)	NC score	0.021404 (rank : 105)
Query Neighborhood Hits	112	Target Neighborhood Hits	75	Shared Neighborhood Hits	2
SwissProt Accessions	P22893, P11520	Gene names	Zfp36, Tis11, Tis11a
Domain Architecture
Description	Tristetraproline (TTP) (Zinc finger protein 36) (Zfp-36) (TIS11A protein) (TIS11) (Growth factor-inducible nuclear protein NUP475) (TPA-induced sequence 11).

VASP_HUMAN
θ value	0.62314 (rank : 52)	NC score	0.018074 (rank : 115)
Query Neighborhood Hits	112	Target Neighborhood Hits	201	Shared Neighborhood Hits	6
SwissProt Accessions	P50552, Q6PIZ1, Q93035	Gene names	VASP
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

KI21B_MOUSE
θ value	0.813845 (rank : 53)	NC score	0.008302 (rank : 139)
Query Neighborhood Hits	112	Target Neighborhood Hits	997	Shared Neighborhood Hits	13
SwissProt Accessions	Q9QXL1, P97424	Gene names	Kif21b, Kif6
Domain Architecture	No domain graphic available
Description	Kinesin family member 21B (Kinesin-like protein KIF6).

ZN286_HUMAN
θ value	0.813845 (rank : 54)	NC score	-0.002350 (rank : 167)
Query Neighborhood Hits	112	Target Neighborhood Hits	775	Shared Neighborhood Hits	4
SwissProt Accessions	Q9HBT8, Q96JF3	Gene names	ZNF286, KIAA1874
Domain Architecture
Description	Zinc finger protein 286.

C2TA_HUMAN
θ value	1.06291 (rank : 55)	NC score	0.019802 (rank : 109)
Query Neighborhood Hits	112	Target Neighborhood Hits	190	Shared Neighborhood Hits	8
SwissProt Accessions	P33076	Gene names	CIITA, MHC2TA
Domain Architecture
Description	MHC class II transactivator (CIITA).

HIRA_HUMAN
θ value	1.06291 (rank : 56)	NC score	0.009093 (rank : 138)
Query Neighborhood Hits	112	Target Neighborhood Hits	279	Shared Neighborhood Hits	2
SwissProt Accessions	P54198, Q8IXN2	Gene names	HIRA, DGCR1, HIR, TUPLE1
Domain Architecture
Description	HIRA protein (TUP1-like enhancer of split protein 1).

KI21B_HUMAN
θ value	1.06291 (rank : 57)	NC score	0.008097 (rank : 140)
Query Neighborhood Hits	112	Target Neighborhood Hits	1017	Shared Neighborhood Hits	14
SwissProt Accessions	O75037, Q5T4J3	Gene names	KIF21B, KIAA0449
Domain Architecture	No domain graphic available
Description	Kinesin family member 21B.

LNX1_HUMAN
θ value	1.06291 (rank : 58)	NC score	0.007218 (rank : 143)
Query Neighborhood Hits	112	Target Neighborhood Hits	379	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

TERF2_HUMAN
θ value	1.06291 (rank : 59)	NC score	0.028356 (rank : 100)
Query Neighborhood Hits	112	Target Neighborhood Hits	102	Shared Neighborhood Hits	6
SwissProt Accessions	Q15554	Gene names	TERF2, TRF2
Domain Architecture
Description	Telomeric repeat-binding factor 2 (TTAGGG repeat-binding factor 2) (Telomeric DNA-binding protein).

TM117_HUMAN
θ value	1.06291 (rank : 60)	NC score	0.039075 (rank : 98)
Query Neighborhood Hits	112	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H0C3	Gene names	TMEM117
Domain Architecture	No domain graphic available
Description	Transmembrane protein 117.

LEUK_HUMAN
θ value	1.38821 (rank : 61)	NC score	0.019064 (rank : 113)
Query Neighborhood Hits	112	Target Neighborhood Hits	213	Shared Neighborhood Hits	7
SwissProt Accessions	P16150	Gene names	SPN, CD43
Domain Architecture	No domain graphic available
Description	Leukosialin precursor (Leukocyte sialoglycoprotein) (Sialophorin) (Galactoglycoprotein) (GALGP) (CD43 antigen).

NIBA_HUMAN
θ value	1.38821 (rank : 62)	NC score	0.019187 (rank : 112)
Query Neighborhood Hits	112	Target Neighborhood Hits	84	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BZQ8, Q5TEM8, Q8TEI5, Q9H593, Q9H9Y8, Q9HCB9	Gene names	C1orf24
Domain Architecture	No domain graphic available
Description	Niban protein.

CP17A_HUMAN
θ value	1.81305 (rank : 63)	NC score	0.003573 (rank : 156)
Query Neighborhood Hits	112	Target Neighborhood Hits	115	Shared Neighborhood Hits	2
SwissProt Accessions	P05093, Q5TZV7	Gene names	CYP17A1, CYP17, S17AH
Domain Architecture
Description	Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17) (P450c17) (Steroid 17-alpha-monooxygenase) (Steroid 17-alpha-hydroxylase/17,20 lyase).

PCLO_MOUSE
θ value	1.81305 (rank : 64)	NC score	0.006774 (rank : 144)
Query Neighborhood Hits	112	Target Neighborhood Hits	2275	Shared Neighborhood Hits	32
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

TOM70_MOUSE
θ value	1.81305 (rank : 65)	NC score	0.021092 (rank : 106)
Query Neighborhood Hits	112	Target Neighborhood Hits	102	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CZW5	Gene names	Tomm70a, D16Wsu109e
Domain Architecture
Description	Mitochondrial precursor proteins import receptor (Translocase of outer membrane TOM70).

TXND2_HUMAN
θ value	1.81305 (rank : 66)	NC score	0.010269 (rank : 132)
Query Neighborhood Hits	112	Target Neighborhood Hits	793	Shared Neighborhood Hits	18
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

PH4H_HUMAN
θ value	2.36792 (rank : 67)	NC score	0.009360 (rank : 137)
Query Neighborhood Hits	112	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	P00439, Q16717, Q8TC14	Gene names	PAH
Domain Architecture
Description	Phenylalanine-4-hydroxylase (EC 1.14.16.1) (PAH) (Phe-4- monooxygenase).

PI51A_MOUSE
θ value	2.36792 (rank : 68)	NC score	0.017780 (rank : 116)
Query Neighborhood Hits	112	Target Neighborhood Hits	21	Shared Neighborhood Hits	5
SwissProt Accessions	P70182, Q8K0D3, Q99L80	Gene names	Pip5k1a, Pip5k1b
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 5-kinase type-1 alpha (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type I alpha) (PtdIns(4)P- 5-kinase alpha) (PIP5KIalpha) (Phosphatidylinositol-4-phosphate 5- kinase type I beta) (PI4P5KIbeta) (68 kDa type I phosphatidylinositol- 4-phosphate 5-kinase).

TDRD6_MOUSE
θ value	2.36792 (rank : 69)	NC score	0.016118 (rank : 122)
Query Neighborhood Hits	112	Target Neighborhood Hits	82	Shared Neighborhood Hits	4
SwissProt Accessions	P61407	Gene names	Tdrd6
Domain Architecture
Description	Tudor domain-containing protein 6.

TOM70_HUMAN
θ value	2.36792 (rank : 70)	NC score	0.019798 (rank : 110)
Query Neighborhood Hits	112	Target Neighborhood Hits	127	Shared Neighborhood Hits	4
SwissProt Accessions	O94826	Gene names	TOMM70A, KIAA0719
Domain Architecture
Description	Mitochondrial precursor proteins import receptor (Translocase of outer membrane TOM70).

C2TA_MOUSE
θ value	3.0926 (rank : 71)	NC score	0.016582 (rank : 121)
Query Neighborhood Hits	112	Target Neighborhood Hits	131	Shared Neighborhood Hits	6
SwissProt Accessions	P79621, O46787, O78036, O78109, Q31115, Q9TPP1	Gene names	Ciita, C2ta, Mhc2ta
Domain Architecture
Description	MHC class II transactivator (CIITA).

PARP4_HUMAN
θ value	3.0926 (rank : 72)	NC score	0.012746 (rank : 127)
Query Neighborhood Hits	112	Target Neighborhood Hits	93	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UKK3, O75903, Q14682, Q9H1M6	Gene names	PARP4, ADPRTL1, KIAA0177, PARPL
Domain Architecture
Description	Poly [ADP-ribose] polymerase 4 (EC 2.4.2.30) (PARP-4) (Vault poly(ADP- ribose) polymerase) (VPARP) (193 kDa vault protein) (PARP- related/IalphaI-related H5/proline-rich) (PH5P).

PI51A_HUMAN
θ value	3.0926 (rank : 73)	NC score	0.017204 (rank : 117)
Query Neighborhood Hits	112	Target Neighborhood Hits	22	Shared Neighborhood Hits	5
SwissProt Accessions	Q99755, Q99754, Q99756	Gene names	PIP5K1A
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 5-kinase type-1 alpha (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type I alpha) (PtdIns(4)P- 5-kinase alpha) (PIP5KIalpha) (68 kDa type I phosphatidylinositol-4- phosphate 5-kinase alpha).

PKN3_MOUSE
θ value	3.0926 (rank : 74)	NC score	0.003351 (rank : 157)
Query Neighborhood Hits	112	Target Neighborhood Hits	1009	Shared Neighborhood Hits	12
SwissProt Accessions	Q8K045	Gene names	Pkn3, Pknbeta
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase N3 (EC 2.7.11.13) (Protein kinase PKN- beta) (Protein-kinase C-related kinase 3).

PO121_MOUSE
θ value	3.0926 (rank : 75)	NC score	0.011378 (rank : 129)
Query Neighborhood Hits	112	Target Neighborhood Hits	345	Shared Neighborhood Hits	9
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

RGPD8_HUMAN
θ value	3.0926 (rank : 76)	NC score	0.020396 (rank : 108)
Query Neighborhood Hits	112	Target Neighborhood Hits	135	Shared Neighborhood Hits	11
SwissProt Accessions	Q99666	Gene names	RGPD8, RANBP2L1
Domain Architecture	No domain graphic available
Description	RANBP2-like and GRIP domain-containing protein 8 (Ran-binding protein 2-like 1) (RanBP2L1) (Sperm membrane protein BS-63).

TITIN_HUMAN
θ value	3.0926 (rank : 77)	NC score	0.003629 (rank : 155)
Query Neighborhood Hits	112	Target Neighborhood Hits	2923	Shared Neighborhood Hits	31
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

AF10_MOUSE
θ value	4.03905 (rank : 78)	NC score	0.010849 (rank : 131)
Query Neighborhood Hits	112	Target Neighborhood Hits	182	Shared Neighborhood Hits	9
SwissProt Accessions	O54826	Gene names	Mllt10, Af10
Domain Architecture
Description	Protein AF-10.

AL2S2_MOUSE
θ value	4.03905 (rank : 79)	NC score	0.000028 (rank : 164)
Query Neighborhood Hits	112	Target Neighborhood Hits	709	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K4T3, Q6P922, Q8BU86, Q8BXK0, Q8K4T2	Gene names	Als2cr2, Papk
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ALS2CR2 (EC 2.7.11.1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein homolog) (ILP-interacting protein homolog) (Polyploidy-associated protein kinase).

BPAEA_HUMAN
θ value	4.03905 (rank : 80)	NC score	0.004500 (rank : 151)
Query Neighborhood Hits	112	Target Neighborhood Hits	1369	Shared Neighborhood Hits	26
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CMTA1_HUMAN
θ value	4.03905 (rank : 81)	NC score	0.009900 (rank : 135)
Query Neighborhood Hits	112	Target Neighborhood Hits	217	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y6Y1, Q5VUE1	Gene names	CAMTA1, KIAA0833
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 1.

K0082_HUMAN
θ value	4.03905 (rank : 82)	NC score	0.018979 (rank : 114)
Query Neighborhood Hits	112	Target Neighborhood Hits	60	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N1G2, Q14670, Q96FJ9	Gene names	KIAA0082
Domain Architecture	No domain graphic available
Description	Protein KIAA0082.

MYST3_HUMAN
θ value	4.03905 (rank : 83)	NC score	0.005042 (rank : 149)
Query Neighborhood Hits	112	Target Neighborhood Hits	772	Shared Neighborhood Hits	15
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

PI51C_MOUSE
θ value	4.03905 (rank : 84)	NC score	0.016595 (rank : 120)
Query Neighborhood Hits	112	Target Neighborhood Hits	25	Shared Neighborhood Hits	5
SwissProt Accessions	O70161, Q505A1, Q80TW9, Q8VCU5	Gene names	Pip5k1c, Kiaa0589
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type I gamma) (PtdIns(4)P- 5-kinase gamma) (PtdInsPKIgamma) (PIP5KIgamma).

RBP22_HUMAN
θ value	4.03905 (rank : 85)	NC score	0.019781 (rank : 111)
Query Neighborhood Hits	112	Target Neighborhood Hits	165	Shared Neighborhood Hits	10
SwissProt Accessions	Q53T03, Q53QN2, Q59GM7	Gene names	RANBP2L2
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 2 (RanBP2L2).

SOX4_MOUSE
θ value	4.03905 (rank : 86)	NC score	0.004480 (rank : 152)
Query Neighborhood Hits	112	Target Neighborhood Hits	108	Shared Neighborhood Hits	2
SwissProt Accessions	Q06831	Gene names	Sox4, Sox-4
Domain Architecture
Description	Transcription factor SOX-4.

ZN318_HUMAN
θ value	4.03905 (rank : 87)	NC score	0.010895 (rank : 130)
Query Neighborhood Hits	112	Target Neighborhood Hits	497	Shared Neighborhood Hits	13
SwissProt Accessions	Q5VUA4, O94796, Q4G0E4, Q8NEM6, Q9UNU8, Q9Y2W9	Gene names	ZNF318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Endocrine regulatory protein).

ZN485_HUMAN
θ value	4.03905 (rank : 88)	NC score	-0.003048 (rank : 168)
Query Neighborhood Hits	112	Target Neighborhood Hits	744	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NCK3, Q96CL0	Gene names	ZNF485
Domain Architecture	No domain graphic available
Description	Zinc finger protein 485.

AL2S2_HUMAN
θ value	5.27518 (rank : 89)	NC score	-0.000626 (rank : 166)
Query Neighborhood Hits	112	Target Neighborhood Hits	727	Shared Neighborhood Hits	4
SwissProt Accessions	Q9C0K7, Q5BKY7, Q9P1L0	Gene names	ALS2CR2, ILPIP
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ALS2CR2 (EC 2.7.11.1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein) (ILP- interacting protein) (CALS-21).

CEP35_HUMAN
θ value	5.27518 (rank : 90)	NC score	0.010009 (rank : 133)
Query Neighborhood Hits	112	Target Neighborhood Hits	811	Shared Neighborhood Hits	23
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

FA21C_HUMAN
θ value	5.27518 (rank : 91)	NC score	0.015024 (rank : 124)
Query Neighborhood Hits	112	Target Neighborhood Hits	194	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y4E1, Q5SQU4, Q5SQU5, Q7L521, Q9UG79	Gene names	FAM21C, KIAA0592
Domain Architecture	No domain graphic available
Description	Protein FAM21C.

MLL2_HUMAN
θ value	5.27518 (rank : 92)	NC score	0.024675 (rank : 102)
Query Neighborhood Hits	112	Target Neighborhood Hits	1788	Shared Neighborhood Hits	31
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MYT1L_MOUSE
θ value	5.27518 (rank : 93)	NC score	0.005756 (rank : 148)
Query Neighborhood Hits	112	Target Neighborhood Hits	461	Shared Neighborhood Hits	11
SwissProt Accessions	P97500, O08996, Q8C643, Q8C7L4, Q8CHB4	Gene names	Myt1l, Kiaa1106, Nzf1, Png1
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1-like protein (MyT1L protein) (Postmitotic neural gene 1 protein) (Zinc finger protein Png-1) (Neural zinc finger factor 1) (NZF-1).

NFAT5_HUMAN
θ value	5.27518 (rank : 94)	NC score	0.006640 (rank : 145)
Query Neighborhood Hits	112	Target Neighborhood Hits	217	Shared Neighborhood Hits	6
SwissProt Accessions	O94916, O95693, Q9UN18	Gene names	NFAT5, KIAA0827, TONEBP
Domain Architecture
Description	Nuclear factor of activated T-cells 5 (T-cell transcription factor NFAT5) (NF-AT5) (Tonicity-responsive enhancer-binding protein) (TonE- binding protein) (TonEBP).

PI51C_HUMAN
θ value	5.27518 (rank : 95)	NC score	0.015558 (rank : 123)
Query Neighborhood Hits	112	Target Neighborhood Hits	109	Shared Neighborhood Hits	5
SwissProt Accessions	O60331, Q7LE07	Gene names	PIP5K1C, KIAA0589
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type I gamma) (PtdIns(4)P- 5-kinase gamma) (PtdInsPKIgamma) (PIP5KIgamma).

TM45A_HUMAN
θ value	5.27518 (rank : 96)	NC score	0.013409 (rank : 126)
Query Neighborhood Hits	112	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NWC5, Q53YW5	Gene names	TMEM45A, DERP7, DNAPTP4
Domain Architecture
Description	Transmembrane protein 45a (Dermal papilla-derived protein 7) (DNA polymerase-transactivated protein 4).

ASPP2_HUMAN
θ value	6.88961 (rank : 97)	NC score	0.002749 (rank : 159)
Query Neighborhood Hits	112	Target Neighborhood Hits	1156	Shared Neighborhood Hits	18
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

CI093_HUMAN
θ value	6.88961 (rank : 98)	NC score	0.002943 (rank : 158)
Query Neighborhood Hits	112	Target Neighborhood Hits	1088	Shared Neighborhood Hits	21
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

GP73_MOUSE
θ value	6.88961 (rank : 99)	NC score	0.007247 (rank : 142)
Query Neighborhood Hits	112	Target Neighborhood Hits	506	Shared Neighborhood Hits	13
SwissProt Accessions	Q91XA2	Gene names	Golph2
Domain Architecture	No domain graphic available
Description	Golgi phosphoprotein 2 (Golgi membrane protein GP73).

KIF9_HUMAN
θ value	6.88961 (rank : 100)	NC score	0.006450 (rank : 146)
Query Neighborhood Hits	112	Target Neighborhood Hits	118	Shared Neighborhood Hits	7
SwissProt Accessions	Q9HAQ2, Q86Z28, Q9H8A4	Gene names	KIF9
Domain Architecture
Description	Kinesin-like protein KIF9.

PCDH9_HUMAN
θ value	6.88961 (rank : 101)	NC score	-0.000139 (rank : 165)
Query Neighborhood Hits	112	Target Neighborhood Hits	180	Shared Neighborhood Hits	4
SwissProt Accessions	Q9HC56	Gene names	PCDH9
Domain Architecture
Description	Protocadherin-9 precursor.

RERE_HUMAN
θ value	6.88961 (rank : 102)	NC score	0.003683 (rank : 154)
Query Neighborhood Hits	112	Target Neighborhood Hits	779	Shared Neighborhood Hits	13
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

ASAH2_MOUSE
θ value	8.99809 (rank : 103)	NC score	0.007375 (rank : 141)
Query Neighborhood Hits	112	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JHE3, Q3UWP9, Q8BNP0, Q8BQN7, Q8R236	Gene names	Asah2
Domain Architecture	No domain graphic available
Description	Neutral ceramidase (EC 3.5.1.23) (NCDase) (N-CDase) (Acylsphingosine deacylase 2) (N-acylsphingosine amidohydrolase 2) [Contains: Neutral ceramidase soluble form].

CENPE_HUMAN
θ value	8.99809 (rank : 104)	NC score	0.002212 (rank : 161)
Query Neighborhood Hits	112	Target Neighborhood Hits	2060	Shared Neighborhood Hits	26
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

DSPP_HUMAN
θ value	8.99809 (rank : 105)	NC score	0.003716 (rank : 153)
Query Neighborhood Hits	112	Target Neighborhood Hits	645	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

HIP1_HUMAN
θ value	8.99809 (rank : 106)	NC score	0.001305 (rank : 162)
Query Neighborhood Hits	112	Target Neighborhood Hits	1016	Shared Neighborhood Hits	20
SwissProt Accessions	O00291, O00328, Q8TDL4	Gene names	HIP1
Domain Architecture
Description	Huntingtin-interacting protein 1 (HIP-I).

KIF5A_HUMAN
θ value	8.99809 (rank : 107)	NC score	0.004582 (rank : 150)
Query Neighborhood Hits	112	Target Neighborhood Hits	843	Shared Neighborhood Hits	15
SwissProt Accessions	Q12840, Q4LE26	Gene names	KIF5A, NKHC1
Domain Architecture
Description	Kinesin heavy chain isoform 5A (Neuronal kinesin heavy chain) (NKHC) (Kinesin heavy chain neuron-specific 1).

LAS1L_HUMAN
θ value	8.99809 (rank : 108)	NC score	0.009911 (rank : 134)
Query Neighborhood Hits	112	Target Neighborhood Hits	57	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y4W2, Q5JXQ0, Q8TEN5, Q9H9V5	Gene names	LAS1L
Domain Architecture	No domain graphic available
Description	LAS1-like protein.

TARA_MOUSE
θ value	8.99809 (rank : 109)	NC score	0.009876 (rank : 136)
Query Neighborhood Hits	112	Target Neighborhood Hits	1133	Shared Neighborhood Hits	19
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TLR1_HUMAN
θ value	8.99809 (rank : 110)	NC score	0.000951 (rank : 163)
Query Neighborhood Hits	112	Target Neighborhood Hits	280	Shared Neighborhood Hits	4
SwissProt Accessions	Q15399, O15452, Q9UG90	Gene names	TLR1, KIAA0012
Domain Architecture
Description	Toll-like receptor 1 precursor (Toll/interleukin-1 receptor-like protein) (TIL) (CD281 antigen).

UT14A_HUMAN
θ value	8.99809 (rank : 111)	NC score	0.006132 (rank : 147)
Query Neighborhood Hits	112	Target Neighborhood Hits	168	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BVJ6, Q5JYF1	Gene names	UTP14A
Domain Architecture	No domain graphic available
Description	U3 small nucleolar RNA-associated protein 14 homolog A (Antigen NY-CO- 16).

ZCH10_MOUSE
θ value	8.99809 (rank : 112)	NC score	0.011605 (rank : 128)
Query Neighborhood Hits	112	Target Neighborhood Hits	133	Shared Neighborhood Hits	6
SwissProt Accessions	Q9CX48	Gene names	Zcchc10
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 10.

AGRIN_HUMAN
θ value	θ > 10 (rank : 113)	NC score	0.064335 (rank : 78)
Query Neighborhood Hits	112	Target Neighborhood Hits	582	Shared Neighborhood Hits	14
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

BMP1_HUMAN
θ value	θ > 10 (rank : 114)	NC score	0.075743 (rank : 69)
Query Neighborhood Hits	112	Target Neighborhood Hits	233	Shared Neighborhood Hits	7
SwissProt Accessions	P13497, Q13292, Q13872, Q14874, Q99421, Q99422, Q99423, Q9UL38	Gene names	BMP1, PCOLC
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

BMP1_MOUSE
θ value	θ > 10 (rank : 115)	NC score	0.075624 (rank : 70)
Query Neighborhood Hits	112	Target Neighborhood Hits	236	Shared Neighborhood Hits	7
SwissProt Accessions	P98063	Gene names	Bmp1
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

CBPD_HUMAN
θ value	θ > 10 (rank : 116)	NC score	0.086468 (rank : 63)
Query Neighborhood Hits	112	Target Neighborhood Hits	53	Shared Neighborhood Hits	4
SwissProt Accessions	O75976, O15377, Q86SH9, Q86XE6	Gene names	CPD
Domain Architecture
Description	Carboxypeptidase D precursor (EC 3.4.17.22) (Metallocarboxypeptidase D) (gp180).

CBPD_MOUSE
θ value	θ > 10 (rank : 117)	NC score	0.086458 (rank : 64)
Query Neighborhood Hits	112	Target Neighborhood Hits	62	Shared Neighborhood Hits	4
SwissProt Accessions	O89001	Gene names	Cpd
Domain Architecture
Description	Carboxypeptidase D precursor (EC 3.4.17.22) (Metallocarboxypeptidase D) (gp180).

CBPE_HUMAN
θ value	θ > 10 (rank : 118)	NC score	0.100323 (rank : 43)
Query Neighborhood Hits	112	Target Neighborhood Hits	28	Shared Neighborhood Hits	4
SwissProt Accessions	P16870, Q9UIU9	Gene names	CPE
Domain Architecture
Description	Carboxypeptidase E precursor (EC 3.4.17.10) (CPE) (Carboxypeptidase H) (CPH) (Enkephalin convertase) (Prohormone-processing carboxypeptidase).

CBPE_MOUSE
θ value	θ > 10 (rank : 119)	NC score	0.100209 (rank : 44)
Query Neighborhood Hits	112	Target Neighborhood Hits	29	Shared Neighborhood Hits	4
SwissProt Accessions	Q00493, Q64439	Gene names	Cpe
Domain Architecture
Description	Carboxypeptidase E precursor (EC 3.4.17.10) (CPE) (Carboxypeptidase H) (CPH) (Enkephalin convertase) (Prohormone-processing carboxypeptidase).

CBPM_HUMAN
θ value	θ > 10 (rank : 120)	NC score	0.089862 (rank : 55)
Query Neighborhood Hits	112	Target Neighborhood Hits	33	Shared Neighborhood Hits	4
SwissProt Accessions	P14384, Q9H2K9	Gene names	CPM
Domain Architecture
Description	Carboxypeptidase M precursor (EC 3.4.17.12) (CPM).

CBPM_MOUSE
θ value	θ > 10 (rank : 121)	NC score	0.090208 (rank : 53)
Query Neighborhood Hits	112	Target Neighborhood Hits	30	Shared Neighborhood Hits	4
SwissProt Accessions	Q80V42, Q497S5, Q9CYH8	Gene names	Cpm
Domain Architecture	No domain graphic available
Description	Carboxypeptidase M precursor (EC 3.4.17.12) (CPM).

CBPN_HUMAN
θ value	θ > 10 (rank : 122)	NC score	0.098632 (rank : 47)
Query Neighborhood Hits	112	Target Neighborhood Hits	32	Shared Neighborhood Hits	4
SwissProt Accessions	P15169	Gene names	CPN1, ACBP
Domain Architecture
Description	Carboxypeptidase N catalytic chain precursor (EC 3.4.17.3) (CPN) (Carboxypeptidase N polypeptide 1) (Carboxypeptidase N small subunit) (Lysine carboxypeptidase) (Arginine carboxypeptidase) (Kininase-1) (Serum carboxypeptidase N) (SCPN) (Anaphylatoxin inactivator) (Plasma carboxypeptidase B).

CBPN_MOUSE
θ value	θ > 10 (rank : 123)	NC score	0.098972 (rank : 46)
Query Neighborhood Hits	112	Target Neighborhood Hits	26	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JJN5, Q91WM9	Gene names	Cpn1
Domain Architecture	No domain graphic available
Description	Carboxypeptidase N catalytic chain precursor (EC 3.4.17.3) (CPN) (Carboxypeptidase N polypeptide 1) (Carboxypeptidase N small subunit).

CBPZ_HUMAN
θ value	θ > 10 (rank : 124)	NC score	0.088082 (rank : 58)
Query Neighborhood Hits	112	Target Neighborhood Hits	69	Shared Neighborhood Hits	4
SwissProt Accessions	Q66K79, O00520, Q96MX2	Gene names	CPZ
Domain Architecture	No domain graphic available
Description	Carboxypeptidase Z precursor (EC 3.4.17.-) (CPZ).

CBPZ_MOUSE
θ value	θ > 10 (rank : 125)	NC score	0.089420 (rank : 56)
Query Neighborhood Hits	112	Target Neighborhood Hits	77	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R4V4	Gene names	Cpz
Domain Architecture	No domain graphic available
Description	Carboxypeptidase Z precursor (EC 3.4.17.-) (CPZ).

CRUM1_HUMAN
θ value	θ > 10 (rank : 126)	NC score	0.051446 (rank : 92)
Query Neighborhood Hits	112	Target Neighborhood Hits	457	Shared Neighborhood Hits	12
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

CRUM1_MOUSE
θ value	θ > 10 (rank : 127)	NC score	0.052172 (rank : 91)
Query Neighborhood Hits	112	Target Neighborhood Hits	444	Shared Neighborhood Hits	12
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

CSMD1_HUMAN
θ value	θ > 10 (rank : 128)	NC score	0.052526 (rank : 88)
Query Neighborhood Hits	112	Target Neighborhood Hits	176	Shared Neighborhood Hits	7
SwissProt Accessions	Q96PZ7, Q96QU9, Q96RM4	Gene names	CSMD1, KIAA1890
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

CSMD1_MOUSE
θ value	θ > 10 (rank : 129)	NC score	0.052187 (rank : 90)
Query Neighborhood Hits	112	Target Neighborhood Hits	193	Shared Neighborhood Hits	7
SwissProt Accessions	Q923L3, Q8BUV1, Q8BYQ3	Gene names	Csmd1
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

CSMD2_HUMAN
θ value	θ > 10 (rank : 130)	NC score	0.056254 (rank : 84)
Query Neighborhood Hits	112	Target Neighborhood Hits	188	Shared Neighborhood Hits	9
SwissProt Accessions	Q7Z408, Q5VT59, Q8N963, Q96Q03, Q9H4V7, Q9H4V8, Q9H4V9, Q9H4W0, Q9H4W1, Q9H4W2, Q9H4W3, Q9H4W4, Q9HCY5, Q9HCY6, Q9HCY7	Gene names	CSMD2, KIAA1884
Domain Architecture
Description	CUB and sushi domain-containing protein 2 (CUB and sushi multiple domains protein 2).

CSMD3_HUMAN
θ value	θ > 10 (rank : 131)	NC score	0.053116 (rank : 87)
Query Neighborhood Hits	112	Target Neighborhood Hits	199	Shared Neighborhood Hits	7
SwissProt Accessions	Q7Z407, Q96PZ3	Gene names	CSMD3, KIAA1894
Domain Architecture
Description	CUB and sushi domain-containing protein 3 precursor (CUB and sushi multiple domains protein 3).

CUBN_HUMAN
θ value	θ > 10 (rank : 132)	NC score	0.086775 (rank : 62)
Query Neighborhood Hits	112	Target Neighborhood Hits	482	Shared Neighborhood Hits	19
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

CUBN_MOUSE
θ value	θ > 10 (rank : 133)	NC score	0.087241 (rank : 61)
Query Neighborhood Hits	112	Target Neighborhood Hits	477	Shared Neighborhood Hits	19
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

CUZD1_HUMAN
θ value	θ > 10 (rank : 134)	NC score	0.087552 (rank : 60)
Query Neighborhood Hits	112	Target Neighborhood Hits	89	Shared Neighborhood Hits	6
SwissProt Accessions	Q86UP6, Q7Z660, Q7Z661, Q86SG1, Q86UP5, Q9HAR7	Gene names	CUZD1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Transmembrane protein UO-44).

CUZD1_MOUSE
θ value	θ > 10 (rank : 135)	NC score	0.082150 (rank : 65)
Query Neighborhood Hits	112	Target Neighborhood Hits	91	Shared Neighborhood Hits	6
SwissProt Accessions	P70412, Q9CTZ7	Gene names	Cuzd1, Itmap1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Integral membrane-associated protein 1).

DCBD1_MOUSE
θ value	θ > 10 (rank : 136)	NC score	0.158435 (rank : 34)
Query Neighborhood Hits	112	Target Neighborhood Hits	89	Shared Neighborhood Hits	7
SwissProt Accessions	Q9D4J3, Q8R327, Q9D696	Gene names	Dcbld1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

DMBT1_MOUSE
θ value	θ > 10 (rank : 137)	NC score	0.064874 (rank : 77)
Query Neighborhood Hits	112	Target Neighborhood Hits	134	Shared Neighborhood Hits	7
SwissProt Accessions	Q60997, Q80YC6, Q9JMJ9	Gene names	Dmbt1, Crpd
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (CRP-ductin) (Vomeroglandin).

GLPC_HUMAN
θ value	θ > 10 (rank : 138)	NC score	0.100918 (rank : 42)
Query Neighborhood Hits	112	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	P04921, Q92642	Gene names	GYPC, GPC
Domain Architecture
Description	Glycophorin C (PAS-2') (Glycoprotein beta) (GLPC) (Glycoconnectin) (Sialoglycoprotein D) (Glycophorin D) (GPD) (CD236 antigen).

GP126_HUMAN
θ value	θ > 10 (rank : 139)	NC score	0.054747 (rank : 85)
Query Neighborhood Hits	112	Target Neighborhood Hits	187	Shared Neighborhood Hits	7
SwissProt Accessions	Q86SQ4, Q6MZU7, Q8NC14, Q96JW0	Gene names	GPR126
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 126 precursor.

LRP12_HUMAN
θ value	θ > 10 (rank : 140)	NC score	0.056324 (rank : 82)
Query Neighborhood Hits	112	Target Neighborhood Hits	205	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y561	Gene names	LRP12, ST7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor (Suppressor of tumorigenicity protein 7).

LRP12_MOUSE
θ value	θ > 10 (rank : 141)	NC score	0.058306 (rank : 81)
Query Neighborhood Hits	112	Target Neighborhood Hits	180	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BUJ9, Q8BWM9	Gene names	Lrp12
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor.

MAMC2_HUMAN
θ value	θ > 10 (rank : 142)	NC score	0.068599 (rank : 76)
Query Neighborhood Hits	112	Target Neighborhood Hits	31	Shared Neighborhood Hits	4
SwissProt Accessions	Q7Z304, Q5VW47, Q8WX43, Q96BM4	Gene names	MAMDC2
Domain Architecture
Description	MAM domain-containing protein 2 precursor.

MAMC2_MOUSE
θ value	θ > 10 (rank : 143)	NC score	0.063995 (rank : 79)
Query Neighborhood Hits	112	Target Neighborhood Hits	31	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CG85, Q8BM24	Gene names	Mamdc2
Domain Architecture
Description	MAM domain-containing protein 2 precursor.

MFRP_HUMAN
θ value	θ > 10 (rank : 144)	NC score	0.079899 (rank : 67)
Query Neighborhood Hits	112	Target Neighborhood Hits	165	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BY79, Q335M3, Q96DQ9	Gene names	MFRP
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

MFRP_MOUSE
θ value	θ > 10 (rank : 145)	NC score	0.081050 (rank : 66)
Query Neighborhood Hits	112	Target Neighborhood Hits	166	Shared Neighborhood Hits	8
SwissProt Accessions	Q8K480, Q8BPP4	Gene names	Mfrp
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

NETO1_HUMAN
θ value	θ > 10 (rank : 146)	NC score	0.095480 (rank : 51)
Query Neighborhood Hits	112	Target Neighborhood Hits	110	Shared Neighborhood Hits	8
SwissProt Accessions	Q8TDF5, Q86W85, Q8ND78, Q8TDF4	Gene names	NETO1, BTCL1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

NETO1_MOUSE
θ value	θ > 10 (rank : 147)	NC score	0.098082 (rank : 48)
Query Neighborhood Hits	112	Target Neighborhood Hits	109	Shared Neighborhood Hits	8
SwissProt Accessions	Q8R4I7, Q80X39, Q8C4S3, Q8CCM2	Gene names	Neto1, Btcl1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

NETO2_HUMAN
θ value	θ > 10 (rank : 148)	NC score	0.101434 (rank : 41)
Query Neighborhood Hits	112	Target Neighborhood Hits	109	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NC67, Q7Z381, Q8ND51, Q96SP4, Q9NVY8	Gene names	NETO2, BTCL2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

NETO2_MOUSE
θ value	θ > 10 (rank : 149)	NC score	0.099441 (rank : 45)
Query Neighborhood Hits	112	Target Neighborhood Hits	113	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BNJ6, Q5VM49, Q8C4Q8	Gene names	Neto2, Btcl2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

NRX1A_HUMAN
θ value	θ > 10 (rank : 150)	NC score	0.091062 (rank : 52)
Query Neighborhood Hits	112	Target Neighborhood Hits	170	Shared Neighborhood Hits	11
SwissProt Accessions	Q9ULB1, O60323, Q53TJ9, Q53TQ1, Q9C079, Q9C080, Q9C081, Q9H3M2, Q9UDM6	Gene names	NRXN1, KIAA0578
Domain Architecture
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

NRX1A_MOUSE
θ value	θ > 10 (rank : 151)	NC score	0.090014 (rank : 54)
Query Neighborhood Hits	112	Target Neighborhood Hits	164	Shared Neighborhood Hits	11
SwissProt Accessions	Q9CS84, O88722, Q80Y87, Q8CHE6	Gene names	Nrxn1, Kiaa0578
Domain Architecture	No domain graphic available
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

NRX2A_HUMAN
θ value	θ > 10 (rank : 152)	NC score	0.077844 (rank : 68)
Query Neighborhood Hits	112	Target Neighborhood Hits	614	Shared Neighborhood Hits	18
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

NRX3A_HUMAN
θ value	θ > 10 (rank : 153)	NC score	0.088036 (rank : 59)
Query Neighborhood Hits	112	Target Neighborhood Hits	164	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y4C0, O95378, Q9NS47, Q9P1V3, Q9P1V6, Q9UIE2, Q9UIE3, Q9ULA5, Q9Y486	Gene names	NRXN3, KIAA0743
Domain Architecture
Description	Neurexin-3-alpha precursor (Neurexin III-alpha).

PCOC1_HUMAN
θ value	θ > 10 (rank : 154)	NC score	0.112312 (rank : 39)
Query Neighborhood Hits	112	Target Neighborhood Hits	146	Shared Neighborhood Hits	9
SwissProt Accessions	Q15113, O14550	Gene names	PCOLCE, PCPE1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein).

PCOC1_MOUSE
θ value	θ > 10 (rank : 155)	NC score	0.114100 (rank : 38)
Query Neighborhood Hits	112	Target Neighborhood Hits	100	Shared Neighborhood Hits	8
SwissProt Accessions	Q61398, O35113	Gene names	Pcolce, Pcpe1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein) (P14).

PCOC2_HUMAN
θ value	θ > 10 (rank : 156)	NC score	0.111431 (rank : 40)
Query Neighborhood Hits	112	Target Neighborhood Hits	73	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UKZ9, Q9BRH3	Gene names	PCOLCE2, PCPE2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

PCOC2_MOUSE
θ value	θ > 10 (rank : 157)	NC score	0.114209 (rank : 37)
Query Neighborhood Hits	112	Target Neighborhood Hits	73	Shared Neighborhood Hits	7
SwissProt Accessions	Q8R4W6, Q3V1K6, Q9CX06	Gene names	Pcolce2, Pcpe2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

PDGFD_HUMAN
θ value	θ > 10 (rank : 158)	NC score	0.088568 (rank : 57)
Query Neighborhood Hits	112	Target Neighborhood Hits	74	Shared Neighborhood Hits	7
SwissProt Accessions	Q9GZP0, Q9BWV5	Gene names	PDGFD, IEGF, SCDGFB
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor D precursor (PDGF D) (Iris-expressed growth factor) (Spinal cord-derived growth factor B) (SCDGF-B).

PDGFD_MOUSE
θ value	θ > 10 (rank : 159)	NC score	0.074785 (rank : 74)
Query Neighborhood Hits	112	Target Neighborhood Hits	72	Shared Neighborhood Hits	6
SwissProt Accessions	Q925I7, Q3URF6, Q8K2L3, Q9D1L8	Gene names	Pdgfd, Scdgfb
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor chain precursor (PDGF D) (Spinal cord- derived growth factor B) (SCDGF-B).

SEZ6L_HUMAN
θ value	θ > 10 (rank : 160)	NC score	0.061183 (rank : 80)
Query Neighborhood Hits	112	Target Neighborhood Hits	289	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.

SHBG_HUMAN
θ value	θ > 10 (rank : 161)	NC score	0.053378 (rank : 86)
Query Neighborhood Hits	112	Target Neighborhood Hits	45	Shared Neighborhood Hits	7
SwissProt Accessions	P04278, P14689, Q16616	Gene names	SHBG
Domain Architecture
Description	Sex hormone-binding globulin precursor (SHBG) (Sex steroid-binding protein) (SBP) (Testis-specific androgen-binding protein) (ABP) (Testosterone-estrogen-binding globulin) (Testosterone-estradiol- binding globulin) (TeBG).

TLL1_HUMAN
θ value	θ > 10 (rank : 162)	NC score	0.074813 (rank : 72)
Query Neighborhood Hits	112	Target Neighborhood Hits	236	Shared Neighborhood Hits	7
SwissProt Accessions	O43897, Q96AN3, Q9NQS4	Gene names	TLL1, TLL
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-).

TLL1_MOUSE
θ value	θ > 10 (rank : 163)	NC score	0.073956 (rank : 75)
Query Neighborhood Hits	112	Target Neighborhood Hits	237	Shared Neighborhood Hits	7
SwissProt Accessions	Q62381, Q3UTT9, Q8BNP5	Gene names	Tll1, Tll
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-) (mTll).

TLL2_HUMAN
θ value	θ > 10 (rank : 164)	NC score	0.074799 (rank : 73)
Query Neighborhood Hits	112	Target Neighborhood Hits	241	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y6L7, Q6PJN5, Q9UQ00	Gene names	TLL2, KIAA0932
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

TLL2_MOUSE
θ value	θ > 10 (rank : 165)	NC score	0.075324 (rank : 71)
Query Neighborhood Hits	112	Target Neighborhood Hits	240	Shared Neighborhood Hits	7
SwissProt Accessions	Q9WVM6	Gene names	Tll2
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

TSG6_HUMAN
θ value	θ > 10 (rank : 166)	NC score	0.096148 (rank : 50)
Query Neighborhood Hits	112	Target Neighborhood Hits	91	Shared Neighborhood Hits	7
SwissProt Accessions	P98066, Q8WWI9	Gene names	TNFAIP6, TSG6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein) (Hyaluronate-binding protein).

TSG6_MOUSE
θ value	θ > 10 (rank : 167)	NC score	0.096649 (rank : 49)
Query Neighborhood Hits	112	Target Neighborhood Hits	91	Shared Neighborhood Hits	7
SwissProt Accessions	O08859	Gene names	Tnfaip6, Tnfip6, Tsg6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein).

ZAN_HUMAN
θ value	θ > 10 (rank : 168)	NC score	0.052497 (rank : 89)
Query Neighborhood Hits	112	Target Neighborhood Hits	679	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

Hits sorted by NC score

FA8_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	112	Target Neighborhood Hits	112	Shared Neighborhood Hits	112
SwissProt Accessions	P00451	Gene names	F8, F8C
Domain Architecture
Description	Coagulation factor VIII precursor (Procoagulant component) (Antihemophilic factor) (AHF) [Contains: Factor VIIIa heavy chain, 200 kDa isoform; Factor VIIIa heavy chain, 92 kDa isoform; Factor VIII B chain; Factor VIIIa light chain].

FA8_MOUSE
NC score	0.989977 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	112	Target Neighborhood Hits	100	Shared Neighborhood Hits	46
SwissProt Accessions	Q06194	Gene names	F8, Cf8, F8c
Domain Architecture
Description	Coagulation factor VIII precursor (Procoagulant component).

FA5_HUMAN
NC score	0.931033 (rank : 3)	θ value	1.46868e-151 (rank : 3)
Query Neighborhood Hits	112	Target Neighborhood Hits	172	Shared Neighborhood Hits	39
SwissProt Accessions	P12259, Q14285, Q6UPU6	Gene names	F5
Domain Architecture
Description	Coagulation factor V precursor (Activated protein C cofactor) [Contains: Coagulation factor V heavy chain; Coagulation factor V light chain].

MFGM_HUMAN
NC score	0.766309 (rank : 4)	θ value	8.55514e-59 (rank : 11)
Query Neighborhood Hits	112	Target Neighborhood Hits	150	Shared Neighborhood Hits	32
SwissProt Accessions	Q08431	Gene names	MFGE8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (HMFG) (Breast epithelial antigen BA46) (MFGM) [Contains: Lactadherin short form; Medin].

XLRS1_MOUSE
NC score	0.729240 (rank : 5)	θ value	3.51386e-20 (rank : 21)
Query Neighborhood Hits	112	Target Neighborhood Hits	32	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Z1L4	Gene names	Rs1, Rs1h, Xlrs1
Domain Architecture
Description	Retinoschisin precursor (X-linked juvenile retinoschisis protein homolog).

XLRS1_HUMAN
NC score	0.728464 (rank : 6)	θ value	1.02238e-19 (rank : 22)
Query Neighborhood Hits	112	Target Neighborhood Hits	32	Shared Neighborhood Hits	31
SwissProt Accessions	O15537	Gene names	RS1, XLRS1
Domain Architecture
Description	Retinoschisin precursor (X-linked juvenile retinoschisis protein).

HEPH_MOUSE
NC score	0.698293 (rank : 7)	θ value	5.8157e-124 (rank : 4)
Query Neighborhood Hits	112	Target Neighborhood Hits	17	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Z0Z4, Q6ZQ65, Q80Y80, Q8C4S2	Gene names	Heph, Kiaa0698
Domain Architecture	No domain graphic available
Description	Hephaestin precursor (EC 1.-.-.-).

CERU_HUMAN
NC score	0.696921 (rank : 8)	θ value	2.52853e-119 (rank : 5)
Query Neighborhood Hits	112	Target Neighborhood Hits	15	Shared Neighborhood Hits	7
SwissProt Accessions	P00450, Q14063, Q2PP18, Q9UKS4	Gene names	CP
Domain Architecture
Description	Ceruloplasmin precursor (EC 1.16.3.1) (Ferroxidase).

HEPH_HUMAN
NC score	0.695653 (rank : 9)	θ value	2.00348e-116 (rank : 6)
Query Neighborhood Hits	112	Target Neighborhood Hits	19	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BQS7, O75180, Q6UW45, Q9C058	Gene names	HEPH, KIAA0698
Domain Architecture	No domain graphic available
Description	Hephaestin precursor (EC 1.-.-.-).

CERU_MOUSE
NC score	0.694526 (rank : 10)	θ value	1.02895e-112 (rank : 7)
Query Neighborhood Hits	112	Target Neighborhood Hits	23	Shared Neighborhood Hits	7
SwissProt Accessions	Q61147	Gene names	Cp
Domain Architecture
Description	Ceruloplasmin precursor (EC 1.16.3.1) (Ferroxidase).

MFGM_MOUSE
NC score	0.666429 (rank : 11)	θ value	5.91091e-68 (rank : 8)
Query Neighborhood Hits	112	Target Neighborhood Hits	233	Shared Neighborhood Hits	32
SwissProt Accessions	P21956, P97800, Q3TBN5, Q9R1X9, Q9WTS3	Gene names	Mfge8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (MFGM) (Sperm surface protein SP47) (MP47).

DCBD2_MOUSE
NC score	0.588061 (rank : 12)	θ value	2.12685e-25 (rank : 17)
Query Neighborhood Hits	112	Target Neighborhood Hits	113	Shared Neighborhood Hits	32
SwissProt Accessions	Q91ZV3, Q8BKI4	Gene names	Dcbld2, Esdn
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein).

DCBD1_HUMAN
NC score	0.588013 (rank : 13)	θ value	4.01107e-24 (rank : 18)
Query Neighborhood Hits	112	Target Neighborhood Hits	110	Shared Neighborhood Hits	33
SwissProt Accessions	Q8N8Z6, Q5H992, Q8IYK5, Q8N7L9, Q96NH2	Gene names	DCBLD1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

DCBD2_HUMAN
NC score	0.576457 (rank : 14)	θ value	3.87602e-27 (rank : 16)
Query Neighborhood Hits	112	Target Neighborhood Hits	118	Shared Neighborhood Hits	33
SwissProt Accessions	Q96PD2, Q8N6M4, Q8TDX2	Gene names	DCBLD2, CLCP1, ESDN
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein) (CUB, LCCL and coagulation factor V/VIII-homology domains protein 1).

EDIL3_HUMAN
NC score	0.550544 (rank : 15)	θ value	1.00825e-67 (rank : 9)
Query Neighborhood Hits	112	Target Neighborhood Hits	292	Shared Neighborhood Hits	32
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

EDIL3_MOUSE
NC score	0.541861 (rank : 16)	θ value	6.53529e-67 (rank : 10)
Query Neighborhood Hits	112	Target Neighborhood Hits	317	Shared Neighborhood Hits	32
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

NRP2_MOUSE
NC score	0.539580 (rank : 17)	θ value	3.99248e-40 (rank : 14)
Query Neighborhood Hits	112	Target Neighborhood Hits	113	Shared Neighborhood Hits	32
SwissProt Accessions	O35375, O35373, O35374, O35376, O35377, O35378	Gene names	Nrp2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

NRP2_HUMAN
NC score	0.537143 (rank : 18)	θ value	2.34062e-40 (rank : 13)
Query Neighborhood Hits	112	Target Neighborhood Hits	120	Shared Neighborhood Hits	32
SwissProt Accessions	O60462, O14820, O14821	Gene names	NRP2, VEGF165R2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

NRP1_MOUSE
NC score	0.533166 (rank : 19)	θ value	3.61106e-41 (rank : 12)
Query Neighborhood Hits	112	Target Neighborhood Hits	120	Shared Neighborhood Hits	31
SwissProt Accessions	P97333	Gene names	Nrp1, Nrp
Domain Architecture
Description	Neuropilin-1 precursor (A5 protein).

NRP1_HUMAN
NC score	0.530262 (rank : 20)	θ value	3.37985e-39 (rank : 15)
Query Neighborhood Hits	112	Target Neighborhood Hits	119	Shared Neighborhood Hits	32
SwissProt Accessions	O14786, O60461, Q96IH5	Gene names	NRP1, NRP, VEGF165R
Domain Architecture
Description	Neuropilin-1 precursor (Vascular endothelial cell growth factor 165 receptor) (CD304 antigen).

CPXM2_MOUSE
NC score	0.481624 (rank : 21)	θ value	4.9032e-22 (rank : 19)
Query Neighborhood Hits	112	Target Neighborhood Hits	58	Shared Neighborhood Hits	31
SwissProt Accessions	Q9D2L5, O54860, Q8VDQ4	Gene names	Cpxm2, Cpx2
Domain Architecture
Description	Carboxypeptidase-like protein X2 precursor.

CPXM2_HUMAN
NC score	0.478823 (rank : 22)	θ value	1.86321e-21 (rank : 20)
Query Neighborhood Hits	112	Target Neighborhood Hits	84	Shared Neighborhood Hits	31
SwissProt Accessions	Q8N436	Gene names	CPXM2
Domain Architecture
Description	Carboxypeptidase-like protein X2 precursor.

CNTP2_HUMAN
NC score	0.463066 (rank : 23)	θ value	4.02038e-16 (rank : 23)
Query Neighborhood Hits	112	Target Neighborhood Hits	199	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UHC6, Q52LV1, Q5H9Q7, Q9UQ12	Gene names	CNTNAP2, CASPR2, KIAA0868
Domain Architecture
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

CNTP3_HUMAN
NC score	0.453587 (rank : 24)	θ value	1.09485e-13 (rank : 29)
Query Neighborhood Hits	112	Target Neighborhood Hits	195	Shared Neighborhood Hits	32
SwissProt Accessions	Q9BZ76, Q9C0E9	Gene names	CNTNAP3, CASPR3, KIAA1714
Domain Architecture
Description	Contactin-associated protein-like 3 precursor (Cell recognition molecule Caspr3).

CNTP2_MOUSE
NC score	0.450711 (rank : 25)	θ value	7.58209e-15 (rank : 28)
Query Neighborhood Hits	112	Target Neighborhood Hits	194	Shared Neighborhood Hits	31
SwissProt Accessions	Q9CPW0, Q6P2K4, Q6ZQ31	Gene names	Cntnap2, Kiaa0868
Domain Architecture	No domain graphic available
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

CNTP4_MOUSE
NC score	0.446204 (rank : 26)	θ value	2.60593e-15 (rank : 26)
Query Neighborhood Hits	112	Target Neighborhood Hits	193	Shared Neighborhood Hits	31
SwissProt Accessions	Q99P47	Gene names	Cntnap4, Caspr4
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

CNTP4_HUMAN
NC score	0.443397 (rank : 27)	θ value	5.8054e-15 (rank : 27)
Query Neighborhood Hits	112	Target Neighborhood Hits	187	Shared Neighborhood Hits	31
SwissProt Accessions	Q9C0A0	Gene names	CNTNAP4, CASPR4, KIAA1763
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

CPXM1_HUMAN
NC score	0.442074 (rank : 28)	θ value	1.16975e-15 (rank : 25)
Query Neighborhood Hits	112	Target Neighborhood Hits	69	Shared Neighborhood Hits	32
SwissProt Accessions	Q96SM3, Q6P4G8, Q6UW65, Q9NUB5	Gene names	CPXM1, CPX1, CPXM
Domain Architecture
Description	Probable carboxypeptidase X1 precursor (EC 3.4.17.-) (Metallocarboxypeptidase CPX-1).

CPXM1_MOUSE
NC score	0.434363 (rank : 29)	θ value	4.02038e-16 (rank : 24)
Query Neighborhood Hits	112	Target Neighborhood Hits	63	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Z100, Q99LA3	Gene names	Cpxm1, Cpx1, Cpxm
Domain Architecture
Description	Probable carboxypeptidase X1 precursor (EC 3.4.17.-) (Metallocarboxypeptidase CPX-1).

CNTP1_HUMAN
NC score	0.421300 (rank : 30)	θ value	6.00763e-12 (rank : 32)
Query Neighborhood Hits	112	Target Neighborhood Hits	196	Shared Neighborhood Hits	32
SwissProt Accessions	P78357	Gene names	CNTNAP1, CASPR, NRXN4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (p190).

CNTP1_MOUSE
NC score	0.419184 (rank : 31)	θ value	6.64225e-11 (rank : 35)
Query Neighborhood Hits	112	Target Neighborhood Hits	183	Shared Neighborhood Hits	32
SwissProt Accessions	O54991	Gene names	Cntnap1, Nrxn4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (Paranodin) (NCP1) (MHDNIV).

DDR2_MOUSE
NC score	0.164178 (rank : 32)	θ value	2.43908e-13 (rank : 30)
Query Neighborhood Hits	112	Target Neighborhood Hits	813	Shared Neighborhood Hits	33
SwissProt Accessions	Q62371	Gene names	Ddr2, Ntrkr3, Tkt, Tyro10
Domain Architecture
Description	Discoidin domain-containing receptor 2 precursor (EC 2.7.10.1) (Discoidin domain receptor 2) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO 10) (Neurotrophic tyrosine kinase, receptor-related 3) (CD167b antigen).

DDR2_HUMAN
NC score	0.162424 (rank : 33)	θ value	7.84624e-12 (rank : 34)
Query Neighborhood Hits	112	Target Neighborhood Hits	818	Shared Neighborhood Hits	33
SwissProt Accessions	Q16832	Gene names	DDR2, NTRKR3, TKT, TYRO10
Domain Architecture
Description	Discoidin domain-containing receptor 2 precursor (EC 2.7.10.1) (Discoidin domain receptor 2) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO 10) (Neurotrophic tyrosine kinase, receptor-related 3) (CD167b antigen).

DCBD1_MOUSE
NC score	0.158435 (rank : 34)	θ value	θ > 10 (rank : 136)
Query Neighborhood Hits	112	Target Neighborhood Hits	89	Shared Neighborhood Hits	7
SwissProt Accessions	Q9D4J3, Q8R327, Q9D696	Gene names	Dcbld1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

DDR1_HUMAN
NC score	0.150869 (rank : 35)	θ value	5.43371e-13 (rank : 31)
Query Neighborhood Hits	112	Target Neighborhood Hits	819	Shared Neighborhood Hits	33
SwissProt Accessions	Q08345, Q14196, Q16562, Q5ST12, Q9UD37	Gene names	DDR1, CAK, EDDR1, RTK6, TRKE
Domain Architecture
Description	Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (TRK E) (Protein-tyrosine kinase RTK 6) (HGK2) (CD167a antigen).

DDR1_MOUSE
NC score	0.143975 (rank : 36)	θ value	6.00763e-12 (rank : 33)
Query Neighborhood Hits	112	Target Neighborhood Hits	818	Shared Neighborhood Hits	33
SwissProt Accessions	Q03146	Gene names	Ddr1, Cak, Eddr1, Mpk6
Domain Architecture
Description	Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (Protein-tyrosine kinase MPK-6) (CD167a antigen).

PCOC2_MOUSE
NC score	0.114209 (rank : 37)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	112	Target Neighborhood Hits	73	Shared Neighborhood Hits	7
SwissProt Accessions	Q8R4W6, Q3V1K6, Q9CX06	Gene names	Pcolce2, Pcpe2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

PCOC1_MOUSE
NC score	0.114100 (rank : 38)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	112	Target Neighborhood Hits	100	Shared Neighborhood Hits	8
SwissProt Accessions	Q61398, O35113	Gene names	Pcolce, Pcpe1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein) (P14).

PCOC1_HUMAN
NC score	0.112312 (rank : 39)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	112	Target Neighborhood Hits	146	Shared Neighborhood Hits	9
SwissProt Accessions	Q15113, O14550	Gene names	PCOLCE, PCPE1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein).

PCOC2_HUMAN
NC score	0.111431 (rank : 40)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	112	Target Neighborhood Hits	73	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UKZ9, Q9BRH3	Gene names	PCOLCE2, PCPE2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

NETO2_HUMAN
NC score	0.101434 (rank : 41)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	112	Target Neighborhood Hits	109	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NC67, Q7Z381, Q8ND51, Q96SP4, Q9NVY8	Gene names	NETO2, BTCL2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

GLPC_HUMAN
NC score	0.100918 (rank : 42)	θ value	θ > 10 (rank : 138)
Query Neighborhood Hits	112	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	P04921, Q92642	Gene names	GYPC, GPC
Domain Architecture
Description	Glycophorin C (PAS-2') (Glycoprotein beta) (GLPC) (Glycoconnectin) (Sialoglycoprotein D) (Glycophorin D) (GPD) (CD236 antigen).

CBPE_HUMAN
NC score	0.100323 (rank : 43)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	112	Target Neighborhood Hits	28	Shared Neighborhood Hits	4
SwissProt Accessions	P16870, Q9UIU9	Gene names	CPE
Domain Architecture
Description	Carboxypeptidase E precursor (EC 3.4.17.10) (CPE) (Carboxypeptidase H) (CPH) (Enkephalin convertase) (Prohormone-processing carboxypeptidase).

CBPE_MOUSE
NC score	0.100209 (rank : 44)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	112	Target Neighborhood Hits	29	Shared Neighborhood Hits	4
SwissProt Accessions	Q00493, Q64439	Gene names	Cpe
Domain Architecture
Description	Carboxypeptidase E precursor (EC 3.4.17.10) (CPE) (Carboxypeptidase H) (CPH) (Enkephalin convertase) (Prohormone-processing carboxypeptidase).

NETO2_MOUSE
NC score	0.099441 (rank : 45)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	112	Target Neighborhood Hits	113	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BNJ6, Q5VM49, Q8C4Q8	Gene names	Neto2, Btcl2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

CBPN_MOUSE
NC score	0.098972 (rank : 46)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	112	Target Neighborhood Hits	26	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JJN5, Q91WM9	Gene names	Cpn1
Domain Architecture	No domain graphic available
Description	Carboxypeptidase N catalytic chain precursor (EC 3.4.17.3) (CPN) (Carboxypeptidase N polypeptide 1) (Carboxypeptidase N small subunit).

CBPN_HUMAN
NC score	0.098632 (rank : 47)	θ value	θ > 10 (rank : 122)
Query Neighborhood Hits	112	Target Neighborhood Hits	32	Shared Neighborhood Hits	4
SwissProt Accessions	P15169	Gene names	CPN1, ACBP
Domain Architecture
Description	Carboxypeptidase N catalytic chain precursor (EC 3.4.17.3) (CPN) (Carboxypeptidase N polypeptide 1) (Carboxypeptidase N small subunit) (Lysine carboxypeptidase) (Arginine carboxypeptidase) (Kininase-1) (Serum carboxypeptidase N) (SCPN) (Anaphylatoxin inactivator) (Plasma carboxypeptidase B).

NETO1_MOUSE
NC score	0.098082 (rank : 48)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	112	Target Neighborhood Hits	109	Shared Neighborhood Hits	8
SwissProt Accessions	Q8R4I7, Q80X39, Q8C4S3, Q8CCM2	Gene names	Neto1, Btcl1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

TSG6_MOUSE
NC score	0.096649 (rank : 49)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	112	Target Neighborhood Hits	91	Shared Neighborhood Hits	7
SwissProt Accessions	O08859	Gene names	Tnfaip6, Tnfip6, Tsg6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein).

TSG6_HUMAN
NC score	0.096148 (rank : 50)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	112	Target Neighborhood Hits	91	Shared Neighborhood Hits	7
SwissProt Accessions	P98066, Q8WWI9	Gene names	TNFAIP6, TSG6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein) (Hyaluronate-binding protein).

NETO1_HUMAN
NC score	0.095480 (rank : 51)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	112	Target Neighborhood Hits	110	Shared Neighborhood Hits	8
SwissProt Accessions	Q8TDF5, Q86W85, Q8ND78, Q8TDF4	Gene names	NETO1, BTCL1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

NRX1A_HUMAN
NC score	0.091062 (rank : 52)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	112	Target Neighborhood Hits	170	Shared Neighborhood Hits	11
SwissProt Accessions	Q9ULB1, O60323, Q53TJ9, Q53TQ1, Q9C079, Q9C080, Q9C081, Q9H3M2, Q9UDM6	Gene names	NRXN1, KIAA0578
Domain Architecture
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

CBPM_MOUSE
NC score	0.090208 (rank : 53)	θ value	θ > 10 (rank : 121)
Query Neighborhood Hits	112	Target Neighborhood Hits	30	Shared Neighborhood Hits	4
SwissProt Accessions	Q80V42, Q497S5, Q9CYH8	Gene names	Cpm
Domain Architecture	No domain graphic available
Description	Carboxypeptidase M precursor (EC 3.4.17.12) (CPM).

NRX1A_MOUSE
NC score	0.090014 (rank : 54)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	112	Target Neighborhood Hits	164	Shared Neighborhood Hits	11
SwissProt Accessions	Q9CS84, O88722, Q80Y87, Q8CHE6	Gene names	Nrxn1, Kiaa0578
Domain Architecture	No domain graphic available
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

CBPM_HUMAN
NC score	0.089862 (rank : 55)	θ value	θ > 10 (rank : 120)
Query Neighborhood Hits	112	Target Neighborhood Hits	33	Shared Neighborhood Hits	4
SwissProt Accessions	P14384, Q9H2K9	Gene names	CPM
Domain Architecture
Description	Carboxypeptidase M precursor (EC 3.4.17.12) (CPM).

CBPZ_MOUSE
NC score	0.089420 (rank : 56)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	112	Target Neighborhood Hits	77	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R4V4	Gene names	Cpz
Domain Architecture	No domain graphic available
Description	Carboxypeptidase Z precursor (EC 3.4.17.-) (CPZ).

PDGFD_HUMAN
NC score	0.088568 (rank : 57)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	112	Target Neighborhood Hits	74	Shared Neighborhood Hits	7
SwissProt Accessions	Q9GZP0, Q9BWV5	Gene names	PDGFD, IEGF, SCDGFB
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor D precursor (PDGF D) (Iris-expressed growth factor) (Spinal cord-derived growth factor B) (SCDGF-B).

CBPZ_HUMAN
NC score	0.088082 (rank : 58)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	112	Target Neighborhood Hits	69	Shared Neighborhood Hits	4
SwissProt Accessions	Q66K79, O00520, Q96MX2	Gene names	CPZ
Domain Architecture	No domain graphic available
Description	Carboxypeptidase Z precursor (EC 3.4.17.-) (CPZ).

NRX3A_HUMAN
NC score	0.088036 (rank : 59)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	112	Target Neighborhood Hits	164	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y4C0, O95378, Q9NS47, Q9P1V3, Q9P1V6, Q9UIE2, Q9UIE3, Q9ULA5, Q9Y486	Gene names	NRXN3, KIAA0743
Domain Architecture
Description	Neurexin-3-alpha precursor (Neurexin III-alpha).

CUZD1_HUMAN
NC score	0.087552 (rank : 60)	θ value	θ > 10 (rank : 134)
Query Neighborhood Hits	112	Target Neighborhood Hits	89	Shared Neighborhood Hits	6
SwissProt Accessions	Q86UP6, Q7Z660, Q7Z661, Q86SG1, Q86UP5, Q9HAR7	Gene names	CUZD1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Transmembrane protein UO-44).

CUBN_MOUSE
NC score	0.087241 (rank : 61)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	112	Target Neighborhood Hits	477	Shared Neighborhood Hits	19
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

CUBN_HUMAN
NC score	0.086775 (rank : 62)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	112	Target Neighborhood Hits	482	Shared Neighborhood Hits	19
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

CBPD_HUMAN
NC score	0.086468 (rank : 63)	θ value	θ > 10 (rank : 116)
Query Neighborhood Hits	112	Target Neighborhood Hits	53	Shared Neighborhood Hits	4
SwissProt Accessions	O75976, O15377, Q86SH9, Q86XE6	Gene names	CPD
Domain Architecture
Description	Carboxypeptidase D precursor (EC 3.4.17.22) (Metallocarboxypeptidase D) (gp180).

CBPD_MOUSE
NC score	0.086458 (rank : 64)	θ value	θ > 10 (rank : 117)
Query Neighborhood Hits	112	Target Neighborhood Hits	62	Shared Neighborhood Hits	4
SwissProt Accessions	O89001	Gene names	Cpd
Domain Architecture
Description	Carboxypeptidase D precursor (EC 3.4.17.22) (Metallocarboxypeptidase D) (gp180).

CUZD1_MOUSE
NC score	0.082150 (rank : 65)	θ value	θ > 10 (rank : 135)
Query Neighborhood Hits	112	Target Neighborhood Hits	91	Shared Neighborhood Hits	6
SwissProt Accessions	P70412, Q9CTZ7	Gene names	Cuzd1, Itmap1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Integral membrane-associated protein 1).

MFRP_MOUSE
NC score	0.081050 (rank : 66)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	112	Target Neighborhood Hits	166	Shared Neighborhood Hits	8
SwissProt Accessions	Q8K480, Q8BPP4	Gene names	Mfrp
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

MFRP_HUMAN
NC score	0.079899 (rank : 67)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	112	Target Neighborhood Hits	165	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BY79, Q335M3, Q96DQ9	Gene names	MFRP
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

NRX2A_HUMAN
NC score	0.077844 (rank : 68)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	112	Target Neighborhood Hits	614	Shared Neighborhood Hits	18
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

BMP1_HUMAN
NC score	0.075743 (rank : 69)	θ value	θ > 10 (rank : 114)
Query Neighborhood Hits	112	Target Neighborhood Hits	233	Shared Neighborhood Hits	7
SwissProt Accessions	P13497, Q13292, Q13872, Q14874, Q99421, Q99422, Q99423, Q9UL38	Gene names	BMP1, PCOLC
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

BMP1_MOUSE
NC score	0.075624 (rank : 70)	θ value	θ > 10 (rank : 115)
Query Neighborhood Hits	112	Target Neighborhood Hits	236	Shared Neighborhood Hits	7
SwissProt Accessions	P98063	Gene names	Bmp1
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

TLL2_MOUSE
NC score	0.075324 (rank : 71)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	112	Target Neighborhood Hits	240	Shared Neighborhood Hits	7
SwissProt Accessions	Q9WVM6	Gene names	Tll2
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

TLL1_HUMAN
NC score	0.074813 (rank : 72)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	112	Target Neighborhood Hits	236	Shared Neighborhood Hits	7
SwissProt Accessions	O43897, Q96AN3, Q9NQS4	Gene names	TLL1, TLL
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-).

TLL2_HUMAN
NC score	0.074799 (rank : 73)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	112	Target Neighborhood Hits	241	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y6L7, Q6PJN5, Q9UQ00	Gene names	TLL2, KIAA0932
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

PDGFD_MOUSE
NC score	0.074785 (rank : 74)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	112	Target Neighborhood Hits	72	Shared Neighborhood Hits	6
SwissProt Accessions	Q925I7, Q3URF6, Q8K2L3, Q9D1L8	Gene names	Pdgfd, Scdgfb
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor chain precursor (PDGF D) (Spinal cord- derived growth factor B) (SCDGF-B).

TLL1_MOUSE
NC score	0.073956 (rank : 75)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	112	Target Neighborhood Hits	237	Shared Neighborhood Hits	7
SwissProt Accessions	Q62381, Q3UTT9, Q8BNP5	Gene names	Tll1, Tll
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-) (mTll).

MAMC2_HUMAN
NC score	0.068599 (rank : 76)	θ value	θ > 10 (rank : 142)
Query Neighborhood Hits	112	Target Neighborhood Hits	31	Shared Neighborhood Hits	4
SwissProt Accessions	Q7Z304, Q5VW47, Q8WX43, Q96BM4	Gene names	MAMDC2
Domain Architecture
Description	MAM domain-containing protein 2 precursor.

DMBT1_MOUSE
NC score	0.064874 (rank : 77)	θ value	θ > 10 (rank : 137)
Query Neighborhood Hits	112	Target Neighborhood Hits	134	Shared Neighborhood Hits	7
SwissProt Accessions	Q60997, Q80YC6, Q9JMJ9	Gene names	Dmbt1, Crpd
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (CRP-ductin) (Vomeroglandin).

AGRIN_HUMAN
NC score	0.064335 (rank : 78)	θ value	θ > 10 (rank : 113)
Query Neighborhood Hits	112	Target Neighborhood Hits	582	Shared Neighborhood Hits	14
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

MAMC2_MOUSE
NC score	0.063995 (rank : 79)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	112	Target Neighborhood Hits	31	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CG85, Q8BM24	Gene names	Mamdc2
Domain Architecture
Description	MAM domain-containing protein 2 precursor.

SEZ6L_HUMAN
NC score	0.061183 (rank : 80)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	112	Target Neighborhood Hits	289	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.

LRP12_MOUSE
NC score	0.058306 (rank : 81)	θ value	θ > 10 (rank : 141)
Query Neighborhood Hits	112	Target Neighborhood Hits	180	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BUJ9, Q8BWM9	Gene names	Lrp12
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor.

LRP12_HUMAN
NC score	0.056324 (rank : 82)	θ value	θ > 10 (rank : 140)
Query Neighborhood Hits	112	Target Neighborhood Hits	205	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y561	Gene names	LRP12, ST7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor (Suppressor of tumorigenicity protein 7).

TM117_MOUSE
NC score	0.056292 (rank : 83)	θ value	0.0431538 (rank : 41)
Query Neighborhood Hits	112	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BH18, Q8C6X8	Gene names	Tmem117
Domain Architecture	No domain graphic available
Description	Transmembrane protein 117.

CSMD2_HUMAN
NC score	0.056254 (rank : 84)	θ value	θ > 10 (rank : 130)
Query Neighborhood Hits	112	Target Neighborhood Hits	188	Shared Neighborhood Hits	9
SwissProt Accessions	Q7Z408, Q5VT59, Q8N963, Q96Q03, Q9H4V7, Q9H4V8, Q9H4V9, Q9H4W0, Q9H4W1, Q9H4W2, Q9H4W3, Q9H4W4, Q9HCY5, Q9HCY6, Q9HCY7	Gene names	CSMD2, KIAA1884
Domain Architecture
Description	CUB and sushi domain-containing protein 2 (CUB and sushi multiple domains protein 2).

GP126_HUMAN
NC score	0.054747 (rank : 85)	θ value	θ > 10 (rank : 139)
Query Neighborhood Hits	112	Target Neighborhood Hits	187	Shared Neighborhood Hits	7
SwissProt Accessions	Q86SQ4, Q6MZU7, Q8NC14, Q96JW0	Gene names	GPR126
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 126 precursor.

SHBG_HUMAN
NC score	0.053378 (rank : 86)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	112	Target Neighborhood Hits	45	Shared Neighborhood Hits	7
SwissProt Accessions	P04278, P14689, Q16616	Gene names	SHBG
Domain Architecture
Description	Sex hormone-binding globulin precursor (SHBG) (Sex steroid-binding protein) (SBP) (Testis-specific androgen-binding protein) (ABP) (Testosterone-estrogen-binding globulin) (Testosterone-estradiol- binding globulin) (TeBG).

CSMD3_HUMAN
NC score	0.053116 (rank : 87)	θ value	θ > 10 (rank : 131)
Query Neighborhood Hits	112	Target Neighborhood Hits	199	Shared Neighborhood Hits	7
SwissProt Accessions	Q7Z407, Q96PZ3	Gene names	CSMD3, KIAA1894
Domain Architecture
Description	CUB and sushi domain-containing protein 3 precursor (CUB and sushi multiple domains protein 3).

CSMD1_HUMAN
NC score	0.052526 (rank : 88)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	112	Target Neighborhood Hits	176	Shared Neighborhood Hits	7
SwissProt Accessions	Q96PZ7, Q96QU9, Q96RM4	Gene names	CSMD1, KIAA1890
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

ZAN_HUMAN
NC score	0.052497 (rank : 89)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	112	Target Neighborhood Hits	679	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

CSMD1_MOUSE
NC score	0.052187 (rank : 90)	θ value	θ > 10 (rank : 129)
Query Neighborhood Hits	112	Target Neighborhood Hits	193	Shared Neighborhood Hits	7
SwissProt Accessions	Q923L3, Q8BUV1, Q8BYQ3	Gene names	Csmd1
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

CRUM1_MOUSE
NC score	0.052172 (rank : 91)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	112	Target Neighborhood Hits	444	Shared Neighborhood Hits	12
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

CRUM1_HUMAN
NC score	0.051446 (rank : 92)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	112	Target Neighborhood Hits	457	Shared Neighborhood Hits	12
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

BORG2_MOUSE
NC score	0.050387 (rank : 93)	θ value	0.0563607 (rank : 42)
Query Neighborhood Hits	112	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CQC5, Q3UD77, Q8BVR7	Gene names	Cdc42ep3, Borg2, Cep3
Domain Architecture	No domain graphic available
Description	Cdc42 effector protein 3 (Binder of Rho GTPases 2).

BORG2_HUMAN
NC score	0.049593 (rank : 94)	θ value	0.0736092 (rank : 43)
Query Neighborhood Hits	112	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UKI2, O95353, Q9UQJ0	Gene names	CDC42EP3, BORG2, CEP3
Domain Architecture	No domain graphic available
Description	Cdc42 effector protein 3 (Binder of Rho GTPases 2) (MSE55-related Cdc42-binding protein).

CALB2_MOUSE
NC score	0.047764 (rank : 95)	θ value	0.0330416 (rank : 36)
Query Neighborhood Hits	112	Target Neighborhood Hits	141	Shared Neighborhood Hits	5
SwissProt Accessions	Q08331, Q60964, Q9JM81	Gene names	Calb2
Domain Architecture
Description	Calretinin (CR).

SSPO_MOUSE
NC score	0.047021 (rank : 96)	θ value	0.0736092 (rank : 44)
Query Neighborhood Hits	112	Target Neighborhood Hits	800	Shared Neighborhood Hits	19
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

CALB2_HUMAN
NC score	0.046698 (rank : 97)	θ value	0.0431538 (rank : 40)
Query Neighborhood Hits	112	Target Neighborhood Hits	149	Shared Neighborhood Hits	5
SwissProt Accessions	P22676, Q53HD2, Q96BK4	Gene names	CALB2, CAB29
Domain Architecture
Description	Calretinin (CR) (29 kDa calbindin).

TM117_HUMAN
NC score	0.039075 (rank : 98)	θ value	1.06291 (rank : 60)
Query Neighborhood Hits	112	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H0C3	Gene names	TMEM117
Domain Architecture	No domain graphic available
Description	Transmembrane protein 117.

K0319_MOUSE
NC score	0.028602 (rank : 99)	θ value	0.163984 (rank : 45)
Query Neighborhood Hits	112	Target Neighborhood Hits	134	Shared Neighborhood Hits	5
SwissProt Accessions	Q5SZV5, Q80U39	Gene names	Kiaa0319
Domain Architecture	No domain graphic available
Description	Protein KIAA0319 precursor.

TERF2_HUMAN
NC score	0.028356 (rank : 100)	θ value	1.06291 (rank : 59)
Query Neighborhood Hits	112	Target Neighborhood Hits	102	Shared Neighborhood Hits	6
SwissProt Accessions	Q15554	Gene names	TERF2, TRF2
Domain Architecture
Description	Telomeric repeat-binding factor 2 (TTAGGG repeat-binding factor 2) (Telomeric DNA-binding protein).

RBM16_HUMAN
NC score	0.025709 (rank : 101)	θ value	0.47712 (rank : 50)
Query Neighborhood Hits	112	Target Neighborhood Hits	300	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UPN6, Q5TBU6, Q9BQN8, Q9BX43	Gene names	RBM16, KIAA1116
Domain Architecture
Description	Putative RNA-binding protein 16 (RNA-binding motif protein 16).

MLL2_HUMAN
NC score	0.024675 (rank : 102)	θ value	5.27518 (rank : 92)
Query Neighborhood Hits	112	Target Neighborhood Hits	1788	Shared Neighborhood Hits	31
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

RTN4_HUMAN
NC score	0.022523 (rank : 103)	θ value	0.21417 (rank : 48)
Query Neighborhood Hits	112	Target Neighborhood Hits	357	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NQC3, O94962, Q9BXG5, Q9H212, Q9H3I3, Q9UQ42, Q9Y293, Q9Y2Y7, Q9Y5U6	Gene names	RTN4, KIAA0886, NOGO
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein) (Foocen) (Neuroendocrine-specific protein) (NSP) (Neuroendocrine-specific protein C homolog) (RTN-x) (Reticulon-5).

MAP4_MOUSE
NC score	0.021624 (rank : 104)	θ value	0.21417 (rank : 47)
Query Neighborhood Hits	112	Target Neighborhood Hits	409	Shared Neighborhood Hits	9
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

TTP_MOUSE
NC score	0.021404 (rank : 105)	θ value	0.62314 (rank : 51)
Query Neighborhood Hits	112	Target Neighborhood Hits	75	Shared Neighborhood Hits	2
SwissProt Accessions	P22893, P11520	Gene names	Zfp36, Tis11, Tis11a
Domain Architecture
Description	Tristetraproline (TTP) (Zinc finger protein 36) (Zfp-36) (TIS11A protein) (TIS11) (Growth factor-inducible nuclear protein NUP475) (TPA-induced sequence 11).

TOM70_MOUSE
NC score	0.021092 (rank : 106)	θ value	1.81305 (rank : 65)
Query Neighborhood Hits	112	Target Neighborhood Hits	102	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CZW5	Gene names	Tomm70a, D16Wsu109e
Domain Architecture
Description	Mitochondrial precursor proteins import receptor (Translocase of outer membrane TOM70).

TOP2B_HUMAN
NC score	0.020983 (rank : 107)	θ value	0.163984 (rank : 46)
Query Neighborhood Hits	112	Target Neighborhood Hits	101	Shared Neighborhood Hits	7
SwissProt Accessions	Q02880, Q13600, Q9UMG8, Q9UQP8	Gene names	TOP2B
Domain Architecture
Description	DNA topoisomerase 2-beta (EC 5.99.1.3) (DNA topoisomerase II, beta isozyme).

RGPD8_HUMAN
NC score	0.020396 (rank : 108)	θ value	3.0926 (rank : 76)
Query Neighborhood Hits	112	Target Neighborhood Hits	135	Shared Neighborhood Hits	11
SwissProt Accessions	Q99666	Gene names	RGPD8, RANBP2L1
Domain Architecture	No domain graphic available
Description	RANBP2-like and GRIP domain-containing protein 8 (Ran-binding protein 2-like 1) (RanBP2L1) (Sperm membrane protein BS-63).

C2TA_HUMAN
NC score	0.019802 (rank : 109)	θ value	1.06291 (rank : 55)
Query Neighborhood Hits	112	Target Neighborhood Hits	190	Shared Neighborhood Hits	8
SwissProt Accessions	P33076	Gene names	CIITA, MHC2TA
Domain Architecture
Description	MHC class II transactivator (CIITA).

TOM70_HUMAN
NC score	0.019798 (rank : 110)	θ value	2.36792 (rank : 70)
Query Neighborhood Hits	112	Target Neighborhood Hits	127	Shared Neighborhood Hits	4
SwissProt Accessions	O94826	Gene names	TOMM70A, KIAA0719
Domain Architecture
Description	Mitochondrial precursor proteins import receptor (Translocase of outer membrane TOM70).

RBP22_HUMAN
NC score	0.019781 (rank : 111)	θ value	4.03905 (rank : 85)
Query Neighborhood Hits	112	Target Neighborhood Hits	165	Shared Neighborhood Hits	10
SwissProt Accessions	Q53T03, Q53QN2, Q59GM7	Gene names	RANBP2L2
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 2 (RanBP2L2).

NIBA_HUMAN
NC score	0.019187 (rank : 112)	θ value	1.38821 (rank : 62)
Query Neighborhood Hits	112	Target Neighborhood Hits	84	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BZQ8, Q5TEM8, Q8TEI5, Q9H593, Q9H9Y8, Q9HCB9	Gene names	C1orf24
Domain Architecture	No domain graphic available
Description	Niban protein.

LEUK_HUMAN
NC score	0.019064 (rank : 113)	θ value	1.38821 (rank : 61)
Query Neighborhood Hits	112	Target Neighborhood Hits	213	Shared Neighborhood Hits	7
SwissProt Accessions	P16150	Gene names	SPN, CD43
Domain Architecture	No domain graphic available
Description	Leukosialin precursor (Leukocyte sialoglycoprotein) (Sialophorin) (Galactoglycoprotein) (GALGP) (CD43 antigen).

K0082_HUMAN
NC score	0.018979 (rank : 114)	θ value	4.03905 (rank : 82)
Query Neighborhood Hits	112	Target Neighborhood Hits	60	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N1G2, Q14670, Q96FJ9	Gene names	KIAA0082
Domain Architecture	No domain graphic available
Description	Protein KIAA0082.

VASP_HUMAN
NC score	0.018074 (rank : 115)	θ value	0.62314 (rank : 52)
Query Neighborhood Hits	112	Target Neighborhood Hits	201	Shared Neighborhood Hits	6
SwissProt Accessions	P50552, Q6PIZ1, Q93035	Gene names	VASP
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

PI51A_MOUSE
NC score	0.017780 (rank : 116)	θ value	2.36792 (rank : 68)
Query Neighborhood Hits	112	Target Neighborhood Hits	21	Shared Neighborhood Hits	5
SwissProt Accessions	P70182, Q8K0D3, Q99L80	Gene names	Pip5k1a, Pip5k1b
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 5-kinase type-1 alpha (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type I alpha) (PtdIns(4)P- 5-kinase alpha) (PIP5KIalpha) (Phosphatidylinositol-4-phosphate 5- kinase type I beta) (PI4P5KIbeta) (68 kDa type I phosphatidylinositol- 4-phosphate 5-kinase).

PI51A_HUMAN
NC score	0.017204 (rank : 117)	θ value	3.0926 (rank : 73)
Query Neighborhood Hits	112	Target Neighborhood Hits	22	Shared Neighborhood Hits	5
SwissProt Accessions	Q99755, Q99754, Q99756	Gene names	PIP5K1A
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 5-kinase type-1 alpha (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type I alpha) (PtdIns(4)P- 5-kinase alpha) (PIP5KIalpha) (68 kDa type I phosphatidylinositol-4- phosphate 5-kinase alpha).

GCC2_HUMAN
NC score	0.017174 (rank : 118)	θ value	0.0330416 (rank : 37)
Query Neighborhood Hits	112	Target Neighborhood Hits	1558	Shared Neighborhood Hits	26
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

RBP24_HUMAN
NC score	0.017167 (rank : 119)	θ value	0.0330416 (rank : 38)
Query Neighborhood Hits	112	Target Neighborhood Hits	1559	Shared Neighborhood Hits	26
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

PI51C_MOUSE
NC score	0.016595 (rank : 120)	θ value	4.03905 (rank : 84)
Query Neighborhood Hits	112	Target Neighborhood Hits	25	Shared Neighborhood Hits	5
SwissProt Accessions	O70161, Q505A1, Q80TW9, Q8VCU5	Gene names	Pip5k1c, Kiaa0589
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type I gamma) (PtdIns(4)P- 5-kinase gamma) (PtdInsPKIgamma) (PIP5KIgamma).

C2TA_MOUSE
NC score	0.016582 (rank : 121)	θ value	3.0926 (rank : 71)
Query Neighborhood Hits	112	Target Neighborhood Hits	131	Shared Neighborhood Hits	6
SwissProt Accessions	P79621, O46787, O78036, O78109, Q31115, Q9TPP1	Gene names	Ciita, C2ta, Mhc2ta
Domain Architecture
Description	MHC class II transactivator (CIITA).

TDRD6_MOUSE
NC score	0.016118 (rank : 122)	θ value	2.36792 (rank : 69)
Query Neighborhood Hits	112	Target Neighborhood Hits	82	Shared Neighborhood Hits	4
SwissProt Accessions	P61407	Gene names	Tdrd6
Domain Architecture
Description	Tudor domain-containing protein 6.

PI51C_HUMAN
NC score	0.015558 (rank : 123)	θ value	5.27518 (rank : 95)
Query Neighborhood Hits	112	Target Neighborhood Hits	109	Shared Neighborhood Hits	5
SwissProt Accessions	O60331, Q7LE07	Gene names	PIP5K1C, KIAA0589
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type I gamma) (PtdIns(4)P- 5-kinase gamma) (PtdInsPKIgamma) (PIP5KIgamma).

FA21C_HUMAN
NC score	0.015024 (rank : 124)	θ value	5.27518 (rank : 91)
Query Neighborhood Hits	112	Target Neighborhood Hits	194	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y4E1, Q5SQU4, Q5SQU5, Q7L521, Q9UG79	Gene names	FAM21C, KIAA0592
Domain Architecture	No domain graphic available
Description	Protein FAM21C.

RBBP6_HUMAN
NC score	0.015000 (rank : 125)	θ value	0.365318 (rank : 49)
Query Neighborhood Hits	112	Target Neighborhood Hits	1135	Shared Neighborhood Hits	22
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

TM45A_HUMAN
NC score	0.013409 (rank : 126)	θ value	5.27518 (rank : 96)
Query Neighborhood Hits	112	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NWC5, Q53YW5	Gene names	TMEM45A, DERP7, DNAPTP4
Domain Architecture
Description	Transmembrane protein 45a (Dermal papilla-derived protein 7) (DNA polymerase-transactivated protein 4).

PARP4_HUMAN
NC score	0.012746 (rank : 127)	θ value	3.0926 (rank : 72)
Query Neighborhood Hits	112	Target Neighborhood Hits	93	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UKK3, O75903, Q14682, Q9H1M6	Gene names	PARP4, ADPRTL1, KIAA0177, PARPL
Domain Architecture
Description	Poly [ADP-ribose] polymerase 4 (EC 2.4.2.30) (PARP-4) (Vault poly(ADP- ribose) polymerase) (VPARP) (193 kDa vault protein) (PARP- related/IalphaI-related H5/proline-rich) (PH5P).

ZCH10_MOUSE
NC score	0.011605 (rank : 128)	θ value	8.99809 (rank : 112)
Query Neighborhood Hits	112	Target Neighborhood Hits	133	Shared Neighborhood Hits	6
SwissProt Accessions	Q9CX48	Gene names	Zcchc10
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 10.

PO121_MOUSE
NC score	0.011378 (rank : 129)	θ value	3.0926 (rank : 75)
Query Neighborhood Hits	112	Target Neighborhood Hits	345	Shared Neighborhood Hits	9
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

ZN318_HUMAN
NC score	0.010895 (rank : 130)	θ value	4.03905 (rank : 87)
Query Neighborhood Hits	112	Target Neighborhood Hits	497	Shared Neighborhood Hits	13
SwissProt Accessions	Q5VUA4, O94796, Q4G0E4, Q8NEM6, Q9UNU8, Q9Y2W9	Gene names	ZNF318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Endocrine regulatory protein).

AF10_MOUSE
NC score	0.010849 (rank : 131)	θ value	4.03905 (rank : 78)
Query Neighborhood Hits	112	Target Neighborhood Hits	182	Shared Neighborhood Hits	9
SwissProt Accessions	O54826	Gene names	Mllt10, Af10
Domain Architecture
Description	Protein AF-10.

TXND2_HUMAN
NC score	0.010269 (rank : 132)	θ value	1.81305 (rank : 66)
Query Neighborhood Hits	112	Target Neighborhood Hits	793	Shared Neighborhood Hits	18
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

CEP35_HUMAN
NC score	0.010009 (rank : 133)	θ value	5.27518 (rank : 90)
Query Neighborhood Hits	112	Target Neighborhood Hits	811	Shared Neighborhood Hits	23
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

LAS1L_HUMAN
NC score	0.009911 (rank : 134)	θ value	8.99809 (rank : 108)
Query Neighborhood Hits	112	Target Neighborhood Hits	57	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y4W2, Q5JXQ0, Q8TEN5, Q9H9V5	Gene names	LAS1L
Domain Architecture	No domain graphic available
Description	LAS1-like protein.

CMTA1_HUMAN
NC score	0.009900 (rank : 135)	θ value	4.03905 (rank : 81)
Query Neighborhood Hits	112	Target Neighborhood Hits	217	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y6Y1, Q5VUE1	Gene names	CAMTA1, KIAA0833
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 1.

TARA_MOUSE
NC score	0.009876 (rank : 136)	θ value	8.99809 (rank : 109)
Query Neighborhood Hits	112	Target Neighborhood Hits	1133	Shared Neighborhood Hits	19
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

PH4H_HUMAN
NC score	0.009360 (rank : 137)	θ value	2.36792 (rank : 67)
Query Neighborhood Hits	112	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	P00439, Q16717, Q8TC14	Gene names	PAH
Domain Architecture
Description	Phenylalanine-4-hydroxylase (EC 1.14.16.1) (PAH) (Phe-4- monooxygenase).

HIRA_HUMAN
NC score	0.009093 (rank : 138)	θ value	1.06291 (rank : 56)
Query Neighborhood Hits	112	Target Neighborhood Hits	279	Shared Neighborhood Hits	2
SwissProt Accessions	P54198, Q8IXN2	Gene names	HIRA, DGCR1, HIR, TUPLE1
Domain Architecture
Description	HIRA protein (TUP1-like enhancer of split protein 1).

KI21B_MOUSE
NC score	0.008302 (rank : 139)	θ value	0.813845 (rank : 53)
Query Neighborhood Hits	112	Target Neighborhood Hits	997	Shared Neighborhood Hits	13
SwissProt Accessions	Q9QXL1, P97424	Gene names	Kif21b, Kif6
Domain Architecture	No domain graphic available
Description	Kinesin family member 21B (Kinesin-like protein KIF6).

KI21B_HUMAN
NC score	0.008097 (rank : 140)	θ value	1.06291 (rank : 57)
Query Neighborhood Hits	112	Target Neighborhood Hits	1017	Shared Neighborhood Hits	14
SwissProt Accessions	O75037, Q5T4J3	Gene names	KIF21B, KIAA0449
Domain Architecture	No domain graphic available
Description	Kinesin family member 21B.

ASAH2_MOUSE
NC score	0.007375 (rank : 141)	θ value	8.99809 (rank : 103)
Query Neighborhood Hits	112	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JHE3, Q3UWP9, Q8BNP0, Q8BQN7, Q8R236	Gene names	Asah2
Domain Architecture	No domain graphic available
Description	Neutral ceramidase (EC 3.5.1.23) (NCDase) (N-CDase) (Acylsphingosine deacylase 2) (N-acylsphingosine amidohydrolase 2) [Contains: Neutral ceramidase soluble form].

GP73_MOUSE
NC score	0.007247 (rank : 142)	θ value	6.88961 (rank : 99)
Query Neighborhood Hits	112	Target Neighborhood Hits	506	Shared Neighborhood Hits	13
SwissProt Accessions	Q91XA2	Gene names	Golph2
Domain Architecture	No domain graphic available
Description	Golgi phosphoprotein 2 (Golgi membrane protein GP73).

LNX1_HUMAN
NC score	0.007218 (rank : 143)	θ value	1.06291 (rank : 58)
Query Neighborhood Hits	112	Target Neighborhood Hits	379	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

PCLO_MOUSE
NC score	0.006774 (rank : 144)	θ value	1.81305 (rank : 64)
Query Neighborhood Hits	112	Target Neighborhood Hits	2275	Shared Neighborhood Hits	32
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

NFAT5_HUMAN
NC score	0.006640 (rank : 145)	θ value	5.27518 (rank : 94)
Query Neighborhood Hits	112	Target Neighborhood Hits	217	Shared Neighborhood Hits	6
SwissProt Accessions	O94916, O95693, Q9UN18	Gene names	NFAT5, KIAA0827, TONEBP
Domain Architecture
Description	Nuclear factor of activated T-cells 5 (T-cell transcription factor NFAT5) (NF-AT5) (Tonicity-responsive enhancer-binding protein) (TonE- binding protein) (TonEBP).

KIF9_HUMAN
NC score	0.006450 (rank : 146)	θ value	6.88961 (rank : 100)
Query Neighborhood Hits	112	Target Neighborhood Hits	118	Shared Neighborhood Hits	7
SwissProt Accessions	Q9HAQ2, Q86Z28, Q9H8A4	Gene names	KIF9
Domain Architecture
Description	Kinesin-like protein KIF9.

UT14A_HUMAN
NC score	0.006132 (rank : 147)	θ value	8.99809 (rank : 111)
Query Neighborhood Hits	112	Target Neighborhood Hits	168	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BVJ6, Q5JYF1	Gene names	UTP14A
Domain Architecture	No domain graphic available
Description	U3 small nucleolar RNA-associated protein 14 homolog A (Antigen NY-CO- 16).

MYT1L_MOUSE
NC score	0.005756 (rank : 148)	θ value	5.27518 (rank : 93)
Query Neighborhood Hits	112	Target Neighborhood Hits	461	Shared Neighborhood Hits	11
SwissProt Accessions	P97500, O08996, Q8C643, Q8C7L4, Q8CHB4	Gene names	Myt1l, Kiaa1106, Nzf1, Png1
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1-like protein (MyT1L protein) (Postmitotic neural gene 1 protein) (Zinc finger protein Png-1) (Neural zinc finger factor 1) (NZF-1).

MYST3_HUMAN
NC score	0.005042 (rank : 149)	θ value	4.03905 (rank : 83)
Query Neighborhood Hits	112	Target Neighborhood Hits	772	Shared Neighborhood Hits	15
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

KIF5A_HUMAN
NC score	0.004582 (rank : 150)	θ value	8.99809 (rank : 107)
Query Neighborhood Hits	112	Target Neighborhood Hits	843	Shared Neighborhood Hits	15
SwissProt Accessions	Q12840, Q4LE26	Gene names	KIF5A, NKHC1
Domain Architecture
Description	Kinesin heavy chain isoform 5A (Neuronal kinesin heavy chain) (NKHC) (Kinesin heavy chain neuron-specific 1).

BPAEA_HUMAN
NC score	0.004500 (rank : 151)	θ value	4.03905 (rank : 80)
Query Neighborhood Hits	112	Target Neighborhood Hits	1369	Shared Neighborhood Hits	26
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

SOX4_MOUSE
NC score	0.004480 (rank : 152)	θ value	4.03905 (rank : 86)
Query Neighborhood Hits	112	Target Neighborhood Hits	108	Shared Neighborhood Hits	2
SwissProt Accessions	Q06831	Gene names	Sox4, Sox-4
Domain Architecture
Description	Transcription factor SOX-4.

DSPP_HUMAN
NC score	0.003716 (rank : 153)	θ value	8.99809 (rank : 105)
Query Neighborhood Hits	112	Target Neighborhood Hits	645	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

RERE_HUMAN
NC score	0.003683 (rank : 154)	θ value	6.88961 (rank : 102)
Query Neighborhood Hits	112	Target Neighborhood Hits	779	Shared Neighborhood Hits	13
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

TITIN_HUMAN
NC score	0.003629 (rank : 155)	θ value	3.0926 (rank : 77)
Query Neighborhood Hits	112	Target Neighborhood Hits	2923	Shared Neighborhood Hits	31
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

CP17A_HUMAN
NC score	0.003573 (rank : 156)	θ value	1.81305 (rank : 63)
Query Neighborhood Hits	112	Target Neighborhood Hits	115	Shared Neighborhood Hits	2
SwissProt Accessions	P05093, Q5TZV7	Gene names	CYP17A1, CYP17, S17AH
Domain Architecture
Description	Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17) (P450c17) (Steroid 17-alpha-monooxygenase) (Steroid 17-alpha-hydroxylase/17,20 lyase).

PKN3_MOUSE
NC score	0.003351 (rank : 157)	θ value	3.0926 (rank : 74)
Query Neighborhood Hits	112	Target Neighborhood Hits	1009	Shared Neighborhood Hits	12
SwissProt Accessions	Q8K045	Gene names	Pkn3, Pknbeta
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase N3 (EC 2.7.11.13) (Protein kinase PKN- beta) (Protein-kinase C-related kinase 3).

CI093_HUMAN
NC score	0.002943 (rank : 158)	θ value	6.88961 (rank : 98)
Query Neighborhood Hits	112	Target Neighborhood Hits	1088	Shared Neighborhood Hits	21
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

ASPP2_HUMAN
NC score	0.002749 (rank : 159)	θ value	6.88961 (rank : 97)
Query Neighborhood Hits	112	Target Neighborhood Hits	1156	Shared Neighborhood Hits	18
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

ZN281_HUMAN
NC score	0.002639 (rank : 160)	θ value	0.0330416 (rank : 39)
Query Neighborhood Hits	112	Target Neighborhood Hits	745	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y2X9, Q9NY92	Gene names	ZNF281, GZP1, ZBP99
Domain Architecture	No domain graphic available
Description	Zinc finger protein 281 (Zinc finger DNA-binding protein 99) (Transcription factor ZBP-99) (GC-box-binding zinc finger protein 1).

CENPE_HUMAN
NC score	0.002212 (rank : 161)	θ value	8.99809 (rank : 104)
Query Neighborhood Hits	112	Target Neighborhood Hits	2060	Shared Neighborhood Hits	26
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

HIP1_HUMAN
NC score	0.001305 (rank : 162)	θ value	8.99809 (rank : 106)
Query Neighborhood Hits	112	Target Neighborhood Hits	1016	Shared Neighborhood Hits	20
SwissProt Accessions	O00291, O00328, Q8TDL4	Gene names	HIP1
Domain Architecture
Description	Huntingtin-interacting protein 1 (HIP-I).

TLR1_HUMAN
NC score	0.000951 (rank : 163)	θ value	8.99809 (rank : 110)
Query Neighborhood Hits	112	Target Neighborhood Hits	280	Shared Neighborhood Hits	4
SwissProt Accessions	Q15399, O15452, Q9UG90	Gene names	TLR1, KIAA0012
Domain Architecture
Description	Toll-like receptor 1 precursor (Toll/interleukin-1 receptor-like protein) (TIL) (CD281 antigen).

AL2S2_MOUSE
NC score	0.000028 (rank : 164)	θ value	4.03905 (rank : 79)
Query Neighborhood Hits	112	Target Neighborhood Hits	709	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K4T3, Q6P922, Q8BU86, Q8BXK0, Q8K4T2	Gene names	Als2cr2, Papk
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ALS2CR2 (EC 2.7.11.1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein homolog) (ILP-interacting protein homolog) (Polyploidy-associated protein kinase).

PCDH9_HUMAN
NC score	-0.000139 (rank : 165)	θ value	6.88961 (rank : 101)
Query Neighborhood Hits	112	Target Neighborhood Hits	180	Shared Neighborhood Hits	4
SwissProt Accessions	Q9HC56	Gene names	PCDH9
Domain Architecture
Description	Protocadherin-9 precursor.

AL2S2_HUMAN
NC score	-0.000626 (rank : 166)	θ value	5.27518 (rank : 89)
Query Neighborhood Hits	112	Target Neighborhood Hits	727	Shared Neighborhood Hits	4
SwissProt Accessions	Q9C0K7, Q5BKY7, Q9P1L0	Gene names	ALS2CR2, ILPIP
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ALS2CR2 (EC 2.7.11.1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein) (ILP- interacting protein) (CALS-21).

ZN286_HUMAN
NC score	-0.002350 (rank : 167)	θ value	0.813845 (rank : 54)
Query Neighborhood Hits	112	Target Neighborhood Hits	775	Shared Neighborhood Hits	4
SwissProt Accessions	Q9HBT8, Q96JF3	Gene names	ZNF286, KIAA1874
Domain Architecture
Description	Zinc finger protein 286.

ZN485_HUMAN
NC score	-0.003048 (rank : 168)	θ value	4.03905 (rank : 88)
Query Neighborhood Hits	112	Target Neighborhood Hits	744	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NCK3, Q96CL0	Gene names	ZNF485
Domain Architecture	No domain graphic available
Description	Zinc finger protein 485.