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Network neighborhood for query Sequence : PH4H_HUMAN

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PH4H_HUMAN
SwissProt Accessions	P00439, Q16717, Q8TC14	Gene names	PAH
Domain Architecture
Description	Phenylalanine-4-hydroxylase (EC 1.14.16.1) (PAH) (Phe-4- monooxygenase).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PH4H_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	P00439, Q16717, Q8TC14	Gene names	PAH
Domain Architecture
Description	Phenylalanine-4-hydroxylase (EC 1.14.16.1) (PAH) (Phe-4- monooxygenase).

PH4H_MOUSE
θ value	0 (rank : 2)	NC score	0.999104 (rank : 2)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	9
SwissProt Accessions	P16331	Gene names	Pah
Domain Architecture
Description	Phenylalanine-4-hydroxylase (EC 1.14.16.1) (PAH) (Phe-4- monooxygenase).

TPH2_HUMAN
θ value	4.00889e-141 (rank : 3)	NC score	0.987701 (rank : 5)
Query Neighborhood Hits	14	Target Neighborhood Hits	13	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IWU9	Gene names	TPH2, NTPH
Domain Architecture
Description	Tryptophan 5-hydroxylase 2 (EC 1.14.16.4) (Tryptophan 5-monooxygenase 2) (Neuronal tryptophan hydroxylase).

TPH1_HUMAN
θ value	4.90052e-139 (rank : 4)	NC score	0.988778 (rank : 3)
Query Neighborhood Hits	14	Target Neighborhood Hits	21	Shared Neighborhood Hits	8
SwissProt Accessions	P17752, O95188, O95189, Q16736	Gene names	TPH1, TPH, TRPH
Domain Architecture
Description	Tryptophan 5-hydroxylase 1 (EC 1.14.16.4) (Tryptophan 5-monooxygenase 1).

TPH1_MOUSE
θ value	6.40027e-139 (rank : 5)	NC score	0.988761 (rank : 4)
Query Neighborhood Hits	14	Target Neighborhood Hits	17	Shared Neighborhood Hits	8
SwissProt Accessions	P17532	Gene names	Tph1, Tph
Domain Architecture
Description	Tryptophan 5-hydroxylase 1 (EC 1.14.16.4) (Tryptophan 5-monooxygenase 1).

TPH2_MOUSE
θ value	2.97304e-136 (rank : 6)	NC score	0.986975 (rank : 6)
Query Neighborhood Hits	14	Target Neighborhood Hits	16	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CGV2	Gene names	Tph2, Ntph
Domain Architecture
Description	Tryptophan 5-hydroxylase 2 (EC 1.14.16.4) (Tryptophan 5-monooxygenase 2) (Neuronal tryptophan hydroxylase).

TY3H_HUMAN
θ value	4.75757e-126 (rank : 7)	NC score	0.985180 (rank : 8)
Query Neighborhood Hits	14	Target Neighborhood Hits	13	Shared Neighborhood Hits	8
SwissProt Accessions	P07101, Q15585, Q15588, Q15589	Gene names	TH, TYH
Domain Architecture
Description	Tyrosine 3-monooxygenase (EC 1.14.16.2) (Tyrosine 3-hydroxylase) (TH).

TY3H_MOUSE
θ value	6.86991e-125 (rank : 8)	NC score	0.985797 (rank : 7)
Query Neighborhood Hits	14	Target Neighborhood Hits	12	Shared Neighborhood Hits	8
SwissProt Accessions	P24529	Gene names	Th
Domain Architecture
Description	Tyrosine 3-monooxygenase (EC 1.14.16.2) (Tyrosine 3-hydroxylase) (TH).

DBR1_MOUSE
θ value	0.0961366 (rank : 9)	NC score	0.065872 (rank : 9)
Query Neighborhood Hits	14	Target Neighborhood Hits	36	Shared Neighborhood Hits	4
SwissProt Accessions	Q923B1, Q8C1T9, Q8C7J7, Q99MT1	Gene names	Dbr1
Domain Architecture	No domain graphic available
Description	Lariat debranching enzyme (EC 3.1.-.-).

FA8_HUMAN
θ value	2.36792 (rank : 10)	NC score	0.009360 (rank : 12)
Query Neighborhood Hits	14	Target Neighborhood Hits	112	Shared Neighborhood Hits	2
SwissProt Accessions	P00451	Gene names	F8, F8C
Domain Architecture
Description	Coagulation factor VIII precursor (Procoagulant component) (Antihemophilic factor) (AHF) [Contains: Factor VIIIa heavy chain, 200 kDa isoform; Factor VIIIa heavy chain, 92 kDa isoform; Factor VIII B chain; Factor VIIIa light chain].

KINH_HUMAN
θ value	2.36792 (rank : 11)	NC score	0.001873 (rank : 14)
Query Neighborhood Hits	14	Target Neighborhood Hits	1231	Shared Neighborhood Hits	2
SwissProt Accessions	P33176, Q5VZ85	Gene names	KIF5B, KNS, KNS1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

CHL1_MOUSE
θ value	3.0926 (rank : 12)	NC score	0.003546 (rank : 13)
Query Neighborhood Hits	14	Target Neighborhood Hits	402	Shared Neighborhood Hits	2
SwissProt Accessions	P70232, Q8BS24, Q8C6W0, Q8C823, Q8VBY7	Gene names	Chl1, Call
Domain Architecture	No domain graphic available
Description	Neural cell adhesion molecule L1-like protein precursor (Cell adhesion molecule with homology to L1CAM) (Close homolog of L1) (Chl1-like protein).

DBR1_HUMAN
θ value	4.03905 (rank : 13)	NC score	0.036451 (rank : 10)
Query Neighborhood Hits	14	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UK59, Q96GH0, Q9NXQ6	Gene names	DBR1
Domain Architecture	No domain graphic available
Description	Lariat debranching enzyme (EC 3.1.-.-).

TDRD4_HUMAN
θ value	8.99809 (rank : 14)	NC score	0.011056 (rank : 11)
Query Neighborhood Hits	14	Target Neighborhood Hits	33	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NUY9	Gene names	TDRD4
Domain Architecture
Description	Tudor domain-containing protein 4.

Hits sorted by NC score

PH4H_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	P00439, Q16717, Q8TC14	Gene names	PAH
Domain Architecture
Description	Phenylalanine-4-hydroxylase (EC 1.14.16.1) (PAH) (Phe-4- monooxygenase).

PH4H_MOUSE
NC score	0.999104 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	9
SwissProt Accessions	P16331	Gene names	Pah
Domain Architecture
Description	Phenylalanine-4-hydroxylase (EC 1.14.16.1) (PAH) (Phe-4- monooxygenase).

TPH1_HUMAN
NC score	0.988778 (rank : 3)	θ value	4.90052e-139 (rank : 4)
Query Neighborhood Hits	14	Target Neighborhood Hits	21	Shared Neighborhood Hits	8
SwissProt Accessions	P17752, O95188, O95189, Q16736	Gene names	TPH1, TPH, TRPH
Domain Architecture
Description	Tryptophan 5-hydroxylase 1 (EC 1.14.16.4) (Tryptophan 5-monooxygenase 1).

TPH1_MOUSE
NC score	0.988761 (rank : 4)	θ value	6.40027e-139 (rank : 5)
Query Neighborhood Hits	14	Target Neighborhood Hits	17	Shared Neighborhood Hits	8
SwissProt Accessions	P17532	Gene names	Tph1, Tph
Domain Architecture
Description	Tryptophan 5-hydroxylase 1 (EC 1.14.16.4) (Tryptophan 5-monooxygenase 1).

TPH2_HUMAN
NC score	0.987701 (rank : 5)	θ value	4.00889e-141 (rank : 3)
Query Neighborhood Hits	14	Target Neighborhood Hits	13	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IWU9	Gene names	TPH2, NTPH
Domain Architecture
Description	Tryptophan 5-hydroxylase 2 (EC 1.14.16.4) (Tryptophan 5-monooxygenase 2) (Neuronal tryptophan hydroxylase).

TPH2_MOUSE
NC score	0.986975 (rank : 6)	θ value	2.97304e-136 (rank : 6)
Query Neighborhood Hits	14	Target Neighborhood Hits	16	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CGV2	Gene names	Tph2, Ntph
Domain Architecture
Description	Tryptophan 5-hydroxylase 2 (EC 1.14.16.4) (Tryptophan 5-monooxygenase 2) (Neuronal tryptophan hydroxylase).

TY3H_MOUSE
NC score	0.985797 (rank : 7)	θ value	6.86991e-125 (rank : 8)
Query Neighborhood Hits	14	Target Neighborhood Hits	12	Shared Neighborhood Hits	8
SwissProt Accessions	P24529	Gene names	Th
Domain Architecture
Description	Tyrosine 3-monooxygenase (EC 1.14.16.2) (Tyrosine 3-hydroxylase) (TH).

TY3H_HUMAN
NC score	0.985180 (rank : 8)	θ value	4.75757e-126 (rank : 7)
Query Neighborhood Hits	14	Target Neighborhood Hits	13	Shared Neighborhood Hits	8
SwissProt Accessions	P07101, Q15585, Q15588, Q15589	Gene names	TH, TYH
Domain Architecture
Description	Tyrosine 3-monooxygenase (EC 1.14.16.2) (Tyrosine 3-hydroxylase) (TH).

DBR1_MOUSE
NC score	0.065872 (rank : 9)	θ value	0.0961366 (rank : 9)
Query Neighborhood Hits	14	Target Neighborhood Hits	36	Shared Neighborhood Hits	4
SwissProt Accessions	Q923B1, Q8C1T9, Q8C7J7, Q99MT1	Gene names	Dbr1
Domain Architecture	No domain graphic available
Description	Lariat debranching enzyme (EC 3.1.-.-).

DBR1_HUMAN
NC score	0.036451 (rank : 10)	θ value	4.03905 (rank : 13)
Query Neighborhood Hits	14	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UK59, Q96GH0, Q9NXQ6	Gene names	DBR1
Domain Architecture	No domain graphic available
Description	Lariat debranching enzyme (EC 3.1.-.-).

TDRD4_HUMAN
NC score	0.011056 (rank : 11)	θ value	8.99809 (rank : 14)
Query Neighborhood Hits	14	Target Neighborhood Hits	33	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NUY9	Gene names	TDRD4
Domain Architecture
Description	Tudor domain-containing protein 4.

FA8_HUMAN
NC score	0.009360 (rank : 12)	θ value	2.36792 (rank : 10)
Query Neighborhood Hits	14	Target Neighborhood Hits	112	Shared Neighborhood Hits	2
SwissProt Accessions	P00451	Gene names	F8, F8C
Domain Architecture
Description	Coagulation factor VIII precursor (Procoagulant component) (Antihemophilic factor) (AHF) [Contains: Factor VIIIa heavy chain, 200 kDa isoform; Factor VIIIa heavy chain, 92 kDa isoform; Factor VIII B chain; Factor VIIIa light chain].

CHL1_MOUSE
NC score	0.003546 (rank : 13)	θ value	3.0926 (rank : 12)
Query Neighborhood Hits	14	Target Neighborhood Hits	402	Shared Neighborhood Hits	2
SwissProt Accessions	P70232, Q8BS24, Q8C6W0, Q8C823, Q8VBY7	Gene names	Chl1, Call
Domain Architecture	No domain graphic available
Description	Neural cell adhesion molecule L1-like protein precursor (Cell adhesion molecule with homology to L1CAM) (Close homolog of L1) (Chl1-like protein).

KINH_HUMAN
NC score	0.001873 (rank : 14)	θ value	2.36792 (rank : 11)
Query Neighborhood Hits	14	Target Neighborhood Hits	1231	Shared Neighborhood Hits	2
SwissProt Accessions	P33176, Q5VZ85	Gene names	KIF5B, KNS, KNS1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).