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Network neighborhood for query Sequence : DBR1_HUMAN

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DBR1_HUMAN
SwissProt Accessions	Q9UK59, Q96GH0, Q9NXQ6	Gene names	DBR1
Domain Architecture	No domain graphic available
Description	Lariat debranching enzyme (EC 3.1.-.-).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

DBR1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	15	Target Neighborhood Hits	15	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UK59, Q96GH0, Q9NXQ6	Gene names	DBR1
Domain Architecture	No domain graphic available
Description	Lariat debranching enzyme (EC 3.1.-.-).

DBR1_MOUSE
θ value	0 (rank : 2)	NC score	0.990175 (rank : 2)
Query Neighborhood Hits	15	Target Neighborhood Hits	36	Shared Neighborhood Hits	7
SwissProt Accessions	Q923B1, Q8C1T9, Q8C7J7, Q99MT1	Gene names	Dbr1
Domain Architecture	No domain graphic available
Description	Lariat debranching enzyme (EC 3.1.-.-).

CEP35_HUMAN
θ value	0.163984 (rank : 3)	NC score	0.045443 (rank : 3)
Query Neighborhood Hits	15	Target Neighborhood Hits	811	Shared Neighborhood Hits	5
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

SUHW4_MOUSE
θ value	1.06291 (rank : 4)	NC score	0.021865 (rank : 11)
Query Neighborhood Hits	15	Target Neighborhood Hits	737	Shared Neighborhood Hits	4
SwissProt Accessions	Q68FE8, Q3T9B1, Q8BI82	Gene names	Suhw4
Domain Architecture	No domain graphic available
Description	Suppressor of hairy wing homolog 4.

COF1_MOUSE
θ value	1.81305 (rank : 5)	NC score	0.033352 (rank : 5)
Query Neighborhood Hits	15	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	P18760	Gene names	Cfl1
Domain Architecture
Description	Cofilin-1 (Cofilin, non-muscle isoform).

TNR6A_HUMAN
θ value	2.36792 (rank : 6)	NC score	0.030970 (rank : 7)
Query Neighborhood Hits	15	Target Neighborhood Hits	343	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NDV7, O15408, Q658L5, Q6NVB5, Q8NEZ0, Q8TBT8, Q8TCR0, Q9NV59, Q9P268	Gene names	TNRC6A, CAGH26, KIAA1460, TNRC6
Domain Architecture	No domain graphic available
Description	Trinucleotide repeat-containing gene 6A protein (CAG repeat protein 26) (Glycine-tryptophan protein of 182 kDa) (GW182 autoantigen) (Protein GW1) (EMSY interactor protein).

PKCB1_HUMAN
θ value	3.0926 (rank : 7)	NC score	0.022031 (rank : 10)
Query Neighborhood Hits	15	Target Neighborhood Hits	488	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

LEO1_HUMAN
θ value	4.03905 (rank : 8)	NC score	0.027053 (rank : 8)
Query Neighborhood Hits	15	Target Neighborhood Hits	958	Shared Neighborhood Hits	7
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

PH4H_HUMAN
θ value	4.03905 (rank : 9)	NC score	0.036451 (rank : 4)
Query Neighborhood Hits	15	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	P00439, Q16717, Q8TC14	Gene names	PAH
Domain Architecture
Description	Phenylalanine-4-hydroxylase (EC 1.14.16.1) (PAH) (Phe-4- monooxygenase).

NBN_HUMAN
θ value	5.27518 (rank : 10)	NC score	0.019579 (rank : 12)
Query Neighborhood Hits	15	Target Neighborhood Hits	226	Shared Neighborhood Hits	3
SwissProt Accessions	O60934, O60672, Q32NF7, Q53FM6, Q63HR6, Q7LDM2	Gene names	NBN, NBS, NBS1, P95
Domain Architecture	No domain graphic available
Description	Nibrin (Nijmegen breakage syndrome protein 1) (Cell cycle regulatory protein p95).

COF1_HUMAN
θ value	6.88961 (rank : 11)	NC score	0.025605 (rank : 9)
Query Neighborhood Hits	15	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	P23528, Q53Y87, Q9UCA2	Gene names	CFL1, CFL
Domain Architecture
Description	Cofilin-1 (Cofilin, non-muscle isoform) (18 kDa phosphoprotein) (p18).

DSPP_MOUSE
θ value	6.88961 (rank : 12)	NC score	0.031811 (rank : 6)
Query Neighborhood Hits	15	Target Neighborhood Hits	491	Shared Neighborhood Hits	6
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

EYA2_MOUSE
θ value	6.88961 (rank : 13)	NC score	0.010987 (rank : 15)
Query Neighborhood Hits	15	Target Neighborhood Hits	43	Shared Neighborhood Hits	2
SwissProt Accessions	O08575, P97925	Gene names	Eya2, Eab1
Domain Architecture
Description	Eyes absent homolog 2 (EC 3.1.3.48).

TTC3_HUMAN
θ value	6.88961 (rank : 14)	NC score	0.012025 (rank : 14)
Query Neighborhood Hits	15	Target Neighborhood Hits	664	Shared Neighborhood Hits	2
SwissProt Accessions	P53804, O60767, P78476, P78477	Gene names	TTC3, TPRD
Domain Architecture
Description	Tetratricopeptide repeat protein 3 (TPR repeat protein 3) (TPR repeat protein D).

IF2P_HUMAN
θ value	8.99809 (rank : 15)	NC score	0.013150 (rank : 13)
Query Neighborhood Hits	15	Target Neighborhood Hits	889	Shared Neighborhood Hits	6
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

Hits sorted by NC score

DBR1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	15	Target Neighborhood Hits	15	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UK59, Q96GH0, Q9NXQ6	Gene names	DBR1
Domain Architecture	No domain graphic available
Description	Lariat debranching enzyme (EC 3.1.-.-).

DBR1_MOUSE
NC score	0.990175 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	15	Target Neighborhood Hits	36	Shared Neighborhood Hits	7
SwissProt Accessions	Q923B1, Q8C1T9, Q8C7J7, Q99MT1	Gene names	Dbr1
Domain Architecture	No domain graphic available
Description	Lariat debranching enzyme (EC 3.1.-.-).

CEP35_HUMAN
NC score	0.045443 (rank : 3)	θ value	0.163984 (rank : 3)
Query Neighborhood Hits	15	Target Neighborhood Hits	811	Shared Neighborhood Hits	5
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

PH4H_HUMAN
NC score	0.036451 (rank : 4)	θ value	4.03905 (rank : 9)
Query Neighborhood Hits	15	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	P00439, Q16717, Q8TC14	Gene names	PAH
Domain Architecture
Description	Phenylalanine-4-hydroxylase (EC 1.14.16.1) (PAH) (Phe-4- monooxygenase).

COF1_MOUSE
NC score	0.033352 (rank : 5)	θ value	1.81305 (rank : 5)
Query Neighborhood Hits	15	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	P18760	Gene names	Cfl1
Domain Architecture
Description	Cofilin-1 (Cofilin, non-muscle isoform).

DSPP_MOUSE
NC score	0.031811 (rank : 6)	θ value	6.88961 (rank : 12)
Query Neighborhood Hits	15	Target Neighborhood Hits	491	Shared Neighborhood Hits	6
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

TNR6A_HUMAN
NC score	0.030970 (rank : 7)	θ value	2.36792 (rank : 6)
Query Neighborhood Hits	15	Target Neighborhood Hits	343	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NDV7, O15408, Q658L5, Q6NVB5, Q8NEZ0, Q8TBT8, Q8TCR0, Q9NV59, Q9P268	Gene names	TNRC6A, CAGH26, KIAA1460, TNRC6
Domain Architecture	No domain graphic available
Description	Trinucleotide repeat-containing gene 6A protein (CAG repeat protein 26) (Glycine-tryptophan protein of 182 kDa) (GW182 autoantigen) (Protein GW1) (EMSY interactor protein).

LEO1_HUMAN
NC score	0.027053 (rank : 8)	θ value	4.03905 (rank : 8)
Query Neighborhood Hits	15	Target Neighborhood Hits	958	Shared Neighborhood Hits	7
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

COF1_HUMAN
NC score	0.025605 (rank : 9)	θ value	6.88961 (rank : 11)
Query Neighborhood Hits	15	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	P23528, Q53Y87, Q9UCA2	Gene names	CFL1, CFL
Domain Architecture
Description	Cofilin-1 (Cofilin, non-muscle isoform) (18 kDa phosphoprotein) (p18).

PKCB1_HUMAN
NC score	0.022031 (rank : 10)	θ value	3.0926 (rank : 7)
Query Neighborhood Hits	15	Target Neighborhood Hits	488	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

SUHW4_MOUSE
NC score	0.021865 (rank : 11)	θ value	1.06291 (rank : 4)
Query Neighborhood Hits	15	Target Neighborhood Hits	737	Shared Neighborhood Hits	4
SwissProt Accessions	Q68FE8, Q3T9B1, Q8BI82	Gene names	Suhw4
Domain Architecture	No domain graphic available
Description	Suppressor of hairy wing homolog 4.

NBN_HUMAN
NC score	0.019579 (rank : 12)	θ value	5.27518 (rank : 10)
Query Neighborhood Hits	15	Target Neighborhood Hits	226	Shared Neighborhood Hits	3
SwissProt Accessions	O60934, O60672, Q32NF7, Q53FM6, Q63HR6, Q7LDM2	Gene names	NBN, NBS, NBS1, P95
Domain Architecture	No domain graphic available
Description	Nibrin (Nijmegen breakage syndrome protein 1) (Cell cycle regulatory protein p95).

IF2P_HUMAN
NC score	0.013150 (rank : 13)	θ value	8.99809 (rank : 15)
Query Neighborhood Hits	15	Target Neighborhood Hits	889	Shared Neighborhood Hits	6
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

TTC3_HUMAN
NC score	0.012025 (rank : 14)	θ value	6.88961 (rank : 14)
Query Neighborhood Hits	15	Target Neighborhood Hits	664	Shared Neighborhood Hits	2
SwissProt Accessions	P53804, O60767, P78476, P78477	Gene names	TTC3, TPRD
Domain Architecture
Description	Tetratricopeptide repeat protein 3 (TPR repeat protein 3) (TPR repeat protein D).

EYA2_MOUSE
NC score	0.010987 (rank : 15)	θ value	6.88961 (rank : 13)
Query Neighborhood Hits	15	Target Neighborhood Hits	43	Shared Neighborhood Hits	2
SwissProt Accessions	O08575, P97925	Gene names	Eya2, Eab1
Domain Architecture
Description	Eyes absent homolog 2 (EC 3.1.3.48).