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Network neighborhood for query Sequence : COF1_HUMAN

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COF1_HUMAN
SwissProt Accessions	P23528, Q53Y87, Q9UCA2	Gene names	CFL1, CFL
Domain Architecture
Description	Cofilin-1 (Cofilin, non-muscle isoform) (18 kDa phosphoprotein) (p18).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

COF1_HUMAN
θ value	9.37149e-90 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	16	Target Neighborhood Hits	16	Shared Neighborhood Hits	16
SwissProt Accessions	P23528, Q53Y87, Q9UCA2	Gene names	CFL1, CFL
Domain Architecture
Description	Cofilin-1 (Cofilin, non-muscle isoform) (18 kDa phosphoprotein) (p18).

COF1_MOUSE
θ value	6.07444e-89 (rank : 2)	NC score	0.999712 (rank : 2)
Query Neighborhood Hits	16	Target Neighborhood Hits	15	Shared Neighborhood Hits	15
SwissProt Accessions	P18760	Gene names	Cfl1
Domain Architecture
Description	Cofilin-1 (Cofilin, non-muscle isoform).

COF2_MOUSE
θ value	4.67263e-73 (rank : 3)	NC score	0.997127 (rank : 3)
Query Neighborhood Hits	16	Target Neighborhood Hits	15	Shared Neighborhood Hits	13
SwissProt Accessions	P45591	Gene names	Cfl2
Domain Architecture
Description	Cofilin-2 (Cofilin, muscle isoform).

COF2_HUMAN
θ value	1.04096e-72 (rank : 4)	NC score	0.997055 (rank : 4)
Query Neighborhood Hits	16	Target Neighborhood Hits	15	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y281	Gene names	CFL2
Domain Architecture
Description	Cofilin-2 (Cofilin, muscle isoform).

DEST_MOUSE
θ value	2.17557e-62 (rank : 5)	NC score	0.990539 (rank : 5)
Query Neighborhood Hits	16	Target Neighborhood Hits	12	Shared Neighborhood Hits	10
SwissProt Accessions	Q9R0P5	Gene names	Dstn, Dsn, Sid23
Domain Architecture
Description	Destrin (Actin-depolymerizing factor) (ADF) (Sid 23).

DEST_HUMAN
θ value	8.26713e-62 (rank : 6)	NC score	0.990068 (rank : 6)
Query Neighborhood Hits	16	Target Neighborhood Hits	11	Shared Neighborhood Hits	10
SwissProt Accessions	P60981, P18282, Q5W166, Q6IAW2	Gene names	DSTN, ACTDP, DSN
Domain Architecture
Description	Destrin (Actin-depolymerizing factor) (ADF).

TWF1_HUMAN
θ value	0.000158464 (rank : 7)	NC score	0.314195 (rank : 8)
Query Neighborhood Hits	16	Target Neighborhood Hits	16	Shared Neighborhood Hits	11
SwissProt Accessions	Q12792, Q59G07, Q5U0B1, Q6FHJ1, Q6FHL6, Q86XL6, Q8TCD3	Gene names	PTK9
Domain Architecture
Description	Twinfilin-1 (Protein A6) (Protein tyrosine kinase 9).

TWF1_MOUSE
θ value	0.000461057 (rank : 8)	NC score	0.316412 (rank : 7)
Query Neighborhood Hits	16	Target Neighborhood Hits	15	Shared Neighborhood Hits	10
SwissProt Accessions	Q91YR1, O09132, Q52L77, Q80X09	Gene names	Ptk9
Domain Architecture
Description	Twinfilin-1 (Protein A6).

TWF2_MOUSE
θ value	0.00175202 (rank : 9)	NC score	0.311450 (rank : 10)
Query Neighborhood Hits	16	Target Neighborhood Hits	30	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Z0P5, Q3TD06, Q3TZG2, Q8BN77, Q9DCK8	Gene names	Ptk9l
Domain Architecture	No domain graphic available
Description	Twinfilin-2 (Twinfilin-1-like protein) (A6-related protein) (mA6RP).

TWF2_HUMAN
θ value	0.00390308 (rank : 10)	NC score	0.314079 (rank : 9)
Query Neighborhood Hits	16	Target Neighborhood Hits	24	Shared Neighborhood Hits	11
SwissProt Accessions	Q6IBS0, Q9Y3F5	Gene names	PTK9L
Domain Architecture	No domain graphic available
Description	Twinfilin-2 (Twinfilin-1-like protein) (A6-related protein) (hA6RP) (Protein tyrosine kinase 9-like).

GMFB_HUMAN
θ value	0.163984 (rank : 11)	NC score	0.139192 (rank : 11)
Query Neighborhood Hits	16	Target Neighborhood Hits	8	Shared Neighborhood Hits	7
SwissProt Accessions	P60983, P17774	Gene names	GMFB
Domain Architecture
Description	Glia maturation factor beta (GMF-beta).

GMFB_MOUSE
θ value	0.62314 (rank : 12)	NC score	0.122314 (rank : 12)
Query Neighborhood Hits	16	Target Neighborhood Hits	8	Shared Neighborhood Hits	7
SwissProt Accessions	Q9CQI3, Q3UQX5, Q9ERL8	Gene names	Gmfb
Domain Architecture
Description	Glia maturation factor beta (GMF-beta).

GMFG_HUMAN
θ value	4.03905 (rank : 13)	NC score	0.091057 (rank : 13)
Query Neighborhood Hits	16	Target Neighborhood Hits	12	Shared Neighborhood Hits	10
SwissProt Accessions	O60234	Gene names	GMFG
Domain Architecture
Description	Glia maturation factor gamma (GMF-gamma).

LRCH2_MOUSE
θ value	5.27518 (rank : 14)	NC score	0.005964 (rank : 16)
Query Neighborhood Hits	16	Target Neighborhood Hits	287	Shared Neighborhood Hits	2
SwissProt Accessions	Q3UMG5, Q7TNP9, Q80TC9	Gene names	Lrch2, Kiaa1495
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and calponin homology domain-containing protein 2.

DBR1_HUMAN
θ value	6.88961 (rank : 15)	NC score	0.025605 (rank : 15)
Query Neighborhood Hits	16	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UK59, Q96GH0, Q9NXQ6	Gene names	DBR1
Domain Architecture	No domain graphic available
Description	Lariat debranching enzyme (EC 3.1.-.-).

K1KB3_MOUSE
θ value	6.88961 (rank : 16)	NC score	0.002747 (rank : 17)
Query Neighborhood Hits	16	Target Neighborhood Hits	179	Shared Neighborhood Hits	3
SwissProt Accessions	P00756	Gene names	Klk1b3, Klk-3, Klk3, Ngfg
Domain Architecture
Description	Kallikrein 1-related peptidase b3 precursor (EC 3.4.21.35) (Glandular kallikrein K3) (Tissue kallikrein-3) (mGK-3) (7S nerve growth factor gamma chain) (Gamma-NGF) [Contains: Nerve growth factor gamma chain 1; Nerve growth factor gamma chain 2].

GMFG_MOUSE
θ value	θ > 10 (rank : 17)	NC score	0.078551 (rank : 14)
Query Neighborhood Hits	16	Target Neighborhood Hits	9	Shared Neighborhood Hits	8
SwissProt Accessions	Q9ERL7	Gene names	Gmfg
Domain Architecture
Description	Glia maturation factor gamma (GMF-gamma).

Hits sorted by NC score

COF1_HUMAN
NC score	0.999962 (rank : 1)	θ value	9.37149e-90 (rank : 1)
Query Neighborhood Hits	16	Target Neighborhood Hits	16	Shared Neighborhood Hits	16
SwissProt Accessions	P23528, Q53Y87, Q9UCA2	Gene names	CFL1, CFL
Domain Architecture
Description	Cofilin-1 (Cofilin, non-muscle isoform) (18 kDa phosphoprotein) (p18).

COF1_MOUSE
NC score	0.999712 (rank : 2)	θ value	6.07444e-89 (rank : 2)
Query Neighborhood Hits	16	Target Neighborhood Hits	15	Shared Neighborhood Hits	15
SwissProt Accessions	P18760	Gene names	Cfl1
Domain Architecture
Description	Cofilin-1 (Cofilin, non-muscle isoform).

COF2_MOUSE
NC score	0.997127 (rank : 3)	θ value	4.67263e-73 (rank : 3)
Query Neighborhood Hits	16	Target Neighborhood Hits	15	Shared Neighborhood Hits	13
SwissProt Accessions	P45591	Gene names	Cfl2
Domain Architecture
Description	Cofilin-2 (Cofilin, muscle isoform).

COF2_HUMAN
NC score	0.997055 (rank : 4)	θ value	1.04096e-72 (rank : 4)
Query Neighborhood Hits	16	Target Neighborhood Hits	15	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y281	Gene names	CFL2
Domain Architecture
Description	Cofilin-2 (Cofilin, muscle isoform).

DEST_MOUSE
NC score	0.990539 (rank : 5)	θ value	2.17557e-62 (rank : 5)
Query Neighborhood Hits	16	Target Neighborhood Hits	12	Shared Neighborhood Hits	10
SwissProt Accessions	Q9R0P5	Gene names	Dstn, Dsn, Sid23
Domain Architecture
Description	Destrin (Actin-depolymerizing factor) (ADF) (Sid 23).

DEST_HUMAN
NC score	0.990068 (rank : 6)	θ value	8.26713e-62 (rank : 6)
Query Neighborhood Hits	16	Target Neighborhood Hits	11	Shared Neighborhood Hits	10
SwissProt Accessions	P60981, P18282, Q5W166, Q6IAW2	Gene names	DSTN, ACTDP, DSN
Domain Architecture
Description	Destrin (Actin-depolymerizing factor) (ADF).

TWF1_MOUSE
NC score	0.316412 (rank : 7)	θ value	0.000461057 (rank : 8)
Query Neighborhood Hits	16	Target Neighborhood Hits	15	Shared Neighborhood Hits	10
SwissProt Accessions	Q91YR1, O09132, Q52L77, Q80X09	Gene names	Ptk9
Domain Architecture
Description	Twinfilin-1 (Protein A6).

TWF1_HUMAN
NC score	0.314195 (rank : 8)	θ value	0.000158464 (rank : 7)
Query Neighborhood Hits	16	Target Neighborhood Hits	16	Shared Neighborhood Hits	11
SwissProt Accessions	Q12792, Q59G07, Q5U0B1, Q6FHJ1, Q6FHL6, Q86XL6, Q8TCD3	Gene names	PTK9
Domain Architecture
Description	Twinfilin-1 (Protein A6) (Protein tyrosine kinase 9).

TWF2_HUMAN
NC score	0.314079 (rank : 9)	θ value	0.00390308 (rank : 10)
Query Neighborhood Hits	16	Target Neighborhood Hits	24	Shared Neighborhood Hits	11
SwissProt Accessions	Q6IBS0, Q9Y3F5	Gene names	PTK9L
Domain Architecture	No domain graphic available
Description	Twinfilin-2 (Twinfilin-1-like protein) (A6-related protein) (hA6RP) (Protein tyrosine kinase 9-like).

TWF2_MOUSE
NC score	0.311450 (rank : 10)	θ value	0.00175202 (rank : 9)
Query Neighborhood Hits	16	Target Neighborhood Hits	30	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Z0P5, Q3TD06, Q3TZG2, Q8BN77, Q9DCK8	Gene names	Ptk9l
Domain Architecture	No domain graphic available
Description	Twinfilin-2 (Twinfilin-1-like protein) (A6-related protein) (mA6RP).

GMFB_HUMAN
NC score	0.139192 (rank : 11)	θ value	0.163984 (rank : 11)
Query Neighborhood Hits	16	Target Neighborhood Hits	8	Shared Neighborhood Hits	7
SwissProt Accessions	P60983, P17774	Gene names	GMFB
Domain Architecture
Description	Glia maturation factor beta (GMF-beta).

GMFB_MOUSE
NC score	0.122314 (rank : 12)	θ value	0.62314 (rank : 12)
Query Neighborhood Hits	16	Target Neighborhood Hits	8	Shared Neighborhood Hits	7
SwissProt Accessions	Q9CQI3, Q3UQX5, Q9ERL8	Gene names	Gmfb
Domain Architecture
Description	Glia maturation factor beta (GMF-beta).

GMFG_HUMAN
NC score	0.091057 (rank : 13)	θ value	4.03905 (rank : 13)
Query Neighborhood Hits	16	Target Neighborhood Hits	12	Shared Neighborhood Hits	10
SwissProt Accessions	O60234	Gene names	GMFG
Domain Architecture
Description	Glia maturation factor gamma (GMF-gamma).

GMFG_MOUSE
NC score	0.078551 (rank : 14)	θ value	θ > 10 (rank : 17)
Query Neighborhood Hits	16	Target Neighborhood Hits	9	Shared Neighborhood Hits	8
SwissProt Accessions	Q9ERL7	Gene names	Gmfg
Domain Architecture
Description	Glia maturation factor gamma (GMF-gamma).

DBR1_HUMAN
NC score	0.025605 (rank : 15)	θ value	6.88961 (rank : 15)
Query Neighborhood Hits	16	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UK59, Q96GH0, Q9NXQ6	Gene names	DBR1
Domain Architecture	No domain graphic available
Description	Lariat debranching enzyme (EC 3.1.-.-).

LRCH2_MOUSE
NC score	0.005964 (rank : 16)	θ value	5.27518 (rank : 14)
Query Neighborhood Hits	16	Target Neighborhood Hits	287	Shared Neighborhood Hits	2
SwissProt Accessions	Q3UMG5, Q7TNP9, Q80TC9	Gene names	Lrch2, Kiaa1495
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and calponin homology domain-containing protein 2.

K1KB3_MOUSE
NC score	0.002747 (rank : 17)	θ value	6.88961 (rank : 16)
Query Neighborhood Hits	16	Target Neighborhood Hits	179	Shared Neighborhood Hits	3
SwissProt Accessions	P00756	Gene names	Klk1b3, Klk-3, Klk3, Ngfg
Domain Architecture
Description	Kallikrein 1-related peptidase b3 precursor (EC 3.4.21.35) (Glandular kallikrein K3) (Tissue kallikrein-3) (mGK-3) (7S nerve growth factor gamma chain) (Gamma-NGF) [Contains: Nerve growth factor gamma chain 1; Nerve growth factor gamma chain 2].