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Network neighborhood for query Sequence : TY3H_MOUSE

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TY3H_MOUSE
SwissProt Accessions	P24529	Gene names	Th
Domain Architecture
Description	Tyrosine 3-monooxygenase (EC 1.14.16.2) (Tyrosine 3-hydroxylase) (TH).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TY3H_HUMAN
θ value	0 (rank : 1)	NC score	0.999128 (rank : 2)
Query Neighborhood Hits	12	Target Neighborhood Hits	13	Shared Neighborhood Hits	8
SwissProt Accessions	P07101, Q15585, Q15588, Q15589	Gene names	TH, TYH
Domain Architecture
Description	Tyrosine 3-monooxygenase (EC 1.14.16.2) (Tyrosine 3-hydroxylase) (TH).

TY3H_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	12	Target Neighborhood Hits	12	Shared Neighborhood Hits	12
SwissProt Accessions	P24529	Gene names	Th
Domain Architecture
Description	Tyrosine 3-monooxygenase (EC 1.14.16.2) (Tyrosine 3-hydroxylase) (TH).

TPH2_HUMAN
θ value	1.38424e-125 (rank : 3)	NC score	0.982715 (rank : 7)
Query Neighborhood Hits	12	Target Neighborhood Hits	13	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IWU9	Gene names	TPH2, NTPH
Domain Architecture
Description	Tryptophan 5-hydroxylase 2 (EC 1.14.16.4) (Tryptophan 5-monooxygenase 2) (Neuronal tryptophan hydroxylase).

PH4H_HUMAN
θ value	6.86991e-125 (rank : 4)	NC score	0.985797 (rank : 4)
Query Neighborhood Hits	12	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	P00439, Q16717, Q8TC14	Gene names	PAH
Domain Architecture
Description	Phenylalanine-4-hydroxylase (EC 1.14.16.1) (PAH) (Phe-4- monooxygenase).

PH4H_MOUSE
θ value	8.97236e-125 (rank : 5)	NC score	0.986006 (rank : 3)
Query Neighborhood Hits	12	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	P16331	Gene names	Pah
Domain Architecture
Description	Phenylalanine-4-hydroxylase (EC 1.14.16.1) (PAH) (Phe-4- monooxygenase).

TPH1_HUMAN
θ value	4.92331e-123 (rank : 6)	NC score	0.983765 (rank : 5)
Query Neighborhood Hits	12	Target Neighborhood Hits	21	Shared Neighborhood Hits	9
SwissProt Accessions	P17752, O95188, O95189, Q16736	Gene names	TPH1, TPH, TRPH
Domain Architecture
Description	Tryptophan 5-hydroxylase 1 (EC 1.14.16.4) (Tryptophan 5-monooxygenase 1).

TPH2_MOUSE
θ value	1.0968e-122 (rank : 7)	NC score	0.982076 (rank : 8)
Query Neighborhood Hits	12	Target Neighborhood Hits	16	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CGV2	Gene names	Tph2, Ntph
Domain Architecture
Description	Tryptophan 5-hydroxylase 2 (EC 1.14.16.4) (Tryptophan 5-monooxygenase 2) (Neuronal tryptophan hydroxylase).

TPH1_MOUSE
θ value	3.19119e-122 (rank : 8)	NC score	0.983511 (rank : 6)
Query Neighborhood Hits	12	Target Neighborhood Hits	17	Shared Neighborhood Hits	8
SwissProt Accessions	P17532	Gene names	Tph1, Tph
Domain Architecture
Description	Tryptophan 5-hydroxylase 1 (EC 1.14.16.4) (Tryptophan 5-monooxygenase 1).

SODE_HUMAN
θ value	1.81305 (rank : 9)	NC score	0.022274 (rank : 9)
Query Neighborhood Hits	12	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	P08294, Q5U781, Q6FHA2	Gene names	SOD3
Domain Architecture
Description	Extracellular superoxide dismutase [Cu-Zn] precursor (EC 1.15.1.1) (EC-SOD).

CBPB2_HUMAN
θ value	6.88961 (rank : 10)	NC score	0.007305 (rank : 11)
Query Neighborhood Hits	12	Target Neighborhood Hits	32	Shared Neighborhood Hits	3
SwissProt Accessions	Q96IY4, Q15114, Q5T9K1, Q5T9K2, Q9P2Y6	Gene names	CPB2
Domain Architecture	No domain graphic available
Description	Carboxypeptidase B2 precursor (EC 3.4.17.20) (Carboxypeptidase U) (CPU) (Thrombin-activable fibrinolysis inhibitor) (TAFI) (Plasma carboxypeptidase B) (pCPB).

DNMT1_MOUSE
θ value	8.99809 (rank : 11)	NC score	0.007119 (rank : 12)
Query Neighborhood Hits	12	Target Neighborhood Hits	137	Shared Neighborhood Hits	2
SwissProt Accessions	P13864, P97413, Q80ZU3, Q9CSC6, Q9QXX6	Gene names	Dnmt1, Dnmt, Met1, Uim
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase MmuI) (DNA MTase MmuI) (MCMT) (M.MmuI) (Met-1).

NU155_HUMAN
θ value	8.99809 (rank : 12)	NC score	0.008230 (rank : 10)
Query Neighborhood Hits	12	Target Neighborhood Hits	44	Shared Neighborhood Hits	2
SwissProt Accessions	O75694, Q9UBE9, Q9UFL5	Gene names	NUP155, KIAA0791
Domain Architecture
Description	Nuclear pore complex protein Nup155 (Nucleoporin Nup155) (155 kDa nucleoporin).

Hits sorted by NC score

TY3H_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	12	Target Neighborhood Hits	12	Shared Neighborhood Hits	12
SwissProt Accessions	P24529	Gene names	Th
Domain Architecture
Description	Tyrosine 3-monooxygenase (EC 1.14.16.2) (Tyrosine 3-hydroxylase) (TH).

TY3H_HUMAN
NC score	0.999128 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	12	Target Neighborhood Hits	13	Shared Neighborhood Hits	8
SwissProt Accessions	P07101, Q15585, Q15588, Q15589	Gene names	TH, TYH
Domain Architecture
Description	Tyrosine 3-monooxygenase (EC 1.14.16.2) (Tyrosine 3-hydroxylase) (TH).

PH4H_MOUSE
NC score	0.986006 (rank : 3)	θ value	8.97236e-125 (rank : 5)
Query Neighborhood Hits	12	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	P16331	Gene names	Pah
Domain Architecture
Description	Phenylalanine-4-hydroxylase (EC 1.14.16.1) (PAH) (Phe-4- monooxygenase).

PH4H_HUMAN
NC score	0.985797 (rank : 4)	θ value	6.86991e-125 (rank : 4)
Query Neighborhood Hits	12	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	P00439, Q16717, Q8TC14	Gene names	PAH
Domain Architecture
Description	Phenylalanine-4-hydroxylase (EC 1.14.16.1) (PAH) (Phe-4- monooxygenase).

TPH1_HUMAN
NC score	0.983765 (rank : 5)	θ value	4.92331e-123 (rank : 6)
Query Neighborhood Hits	12	Target Neighborhood Hits	21	Shared Neighborhood Hits	9
SwissProt Accessions	P17752, O95188, O95189, Q16736	Gene names	TPH1, TPH, TRPH
Domain Architecture
Description	Tryptophan 5-hydroxylase 1 (EC 1.14.16.4) (Tryptophan 5-monooxygenase 1).

TPH1_MOUSE
NC score	0.983511 (rank : 6)	θ value	3.19119e-122 (rank : 8)
Query Neighborhood Hits	12	Target Neighborhood Hits	17	Shared Neighborhood Hits	8
SwissProt Accessions	P17532	Gene names	Tph1, Tph
Domain Architecture
Description	Tryptophan 5-hydroxylase 1 (EC 1.14.16.4) (Tryptophan 5-monooxygenase 1).

TPH2_HUMAN
NC score	0.982715 (rank : 7)	θ value	1.38424e-125 (rank : 3)
Query Neighborhood Hits	12	Target Neighborhood Hits	13	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IWU9	Gene names	TPH2, NTPH
Domain Architecture
Description	Tryptophan 5-hydroxylase 2 (EC 1.14.16.4) (Tryptophan 5-monooxygenase 2) (Neuronal tryptophan hydroxylase).

TPH2_MOUSE
NC score	0.982076 (rank : 8)	θ value	1.0968e-122 (rank : 7)
Query Neighborhood Hits	12	Target Neighborhood Hits	16	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CGV2	Gene names	Tph2, Ntph
Domain Architecture
Description	Tryptophan 5-hydroxylase 2 (EC 1.14.16.4) (Tryptophan 5-monooxygenase 2) (Neuronal tryptophan hydroxylase).

SODE_HUMAN
NC score	0.022274 (rank : 9)	θ value	1.81305 (rank : 9)
Query Neighborhood Hits	12	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	P08294, Q5U781, Q6FHA2	Gene names	SOD3
Domain Architecture
Description	Extracellular superoxide dismutase [Cu-Zn] precursor (EC 1.15.1.1) (EC-SOD).

NU155_HUMAN
NC score	0.008230 (rank : 10)	θ value	8.99809 (rank : 12)
Query Neighborhood Hits	12	Target Neighborhood Hits	44	Shared Neighborhood Hits	2
SwissProt Accessions	O75694, Q9UBE9, Q9UFL5	Gene names	NUP155, KIAA0791
Domain Architecture
Description	Nuclear pore complex protein Nup155 (Nucleoporin Nup155) (155 kDa nucleoporin).

CBPB2_HUMAN
NC score	0.007305 (rank : 11)	θ value	6.88961 (rank : 10)
Query Neighborhood Hits	12	Target Neighborhood Hits	32	Shared Neighborhood Hits	3
SwissProt Accessions	Q96IY4, Q15114, Q5T9K1, Q5T9K2, Q9P2Y6	Gene names	CPB2
Domain Architecture	No domain graphic available
Description	Carboxypeptidase B2 precursor (EC 3.4.17.20) (Carboxypeptidase U) (CPU) (Thrombin-activable fibrinolysis inhibitor) (TAFI) (Plasma carboxypeptidase B) (pCPB).

DNMT1_MOUSE
NC score	0.007119 (rank : 12)	θ value	8.99809 (rank : 11)
Query Neighborhood Hits	12	Target Neighborhood Hits	137	Shared Neighborhood Hits	2
SwissProt Accessions	P13864, P97413, Q80ZU3, Q9CSC6, Q9QXX6	Gene names	Dnmt1, Dnmt, Met1, Uim
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase MmuI) (DNA MTase MmuI) (MCMT) (M.MmuI) (Met-1).