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Network neighborhood for query Sequence : PH4H_MOUSE

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PH4H_MOUSE
SwissProt Accessions	P16331	Gene names	Pah
Domain Architecture
Description	Phenylalanine-4-hydroxylase (EC 1.14.16.1) (PAH) (Phe-4- monooxygenase).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PH4H_HUMAN
θ value	0 (rank : 1)	NC score	0.999104 (rank : 2)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	9
SwissProt Accessions	P00439, Q16717, Q8TC14	Gene names	PAH
Domain Architecture
Description	Phenylalanine-4-hydroxylase (EC 1.14.16.1) (PAH) (Phe-4- monooxygenase).

PH4H_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	P16331	Gene names	Pah
Domain Architecture
Description	Phenylalanine-4-hydroxylase (EC 1.14.16.1) (PAH) (Phe-4- monooxygenase).

TPH2_HUMAN
θ value	1.05497e-141 (rank : 3)	NC score	0.987929 (rank : 5)
Query Neighborhood Hits	14	Target Neighborhood Hits	13	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IWU9	Gene names	TPH2, NTPH
Domain Architecture
Description	Tryptophan 5-hydroxylase 2 (EC 1.14.16.4) (Tryptophan 5-monooxygenase 2) (Neuronal tryptophan hydroxylase).

TPH1_HUMAN
θ value	5.78879e-140 (rank : 4)	NC score	0.989015 (rank : 3)
Query Neighborhood Hits	14	Target Neighborhood Hits	21	Shared Neighborhood Hits	8
SwissProt Accessions	P17752, O95188, O95189, Q16736	Gene names	TPH1, TPH, TRPH
Domain Architecture
Description	Tryptophan 5-hydroxylase 1 (EC 1.14.16.4) (Tryptophan 5-monooxygenase 1).

TPH1_MOUSE
θ value	7.56041e-140 (rank : 5)	NC score	0.988996 (rank : 4)
Query Neighborhood Hits	14	Target Neighborhood Hits	17	Shared Neighborhood Hits	8
SwissProt Accessions	P17532	Gene names	Tph1, Tph
Domain Architecture
Description	Tryptophan 5-hydroxylase 1 (EC 1.14.16.4) (Tryptophan 5-monooxygenase 1).

TPH2_MOUSE
θ value	2.689e-137 (rank : 6)	NC score	0.987213 (rank : 6)
Query Neighborhood Hits	14	Target Neighborhood Hits	16	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CGV2	Gene names	Tph2, Ntph
Domain Architecture
Description	Tryptophan 5-hydroxylase 2 (EC 1.14.16.4) (Tryptophan 5-monooxygenase 2) (Neuronal tryptophan hydroxylase).

TY3H_HUMAN
θ value	1.13238e-127 (rank : 7)	NC score	0.985427 (rank : 8)
Query Neighborhood Hits	14	Target Neighborhood Hits	13	Shared Neighborhood Hits	8
SwissProt Accessions	P07101, Q15585, Q15588, Q15589	Gene names	TH, TYH
Domain Architecture
Description	Tyrosine 3-monooxygenase (EC 1.14.16.2) (Tyrosine 3-hydroxylase) (TH).

TY3H_MOUSE
θ value	8.97236e-125 (rank : 8)	NC score	0.986006 (rank : 7)
Query Neighborhood Hits	14	Target Neighborhood Hits	12	Shared Neighborhood Hits	8
SwissProt Accessions	P24529	Gene names	Th
Domain Architecture
Description	Tyrosine 3-monooxygenase (EC 1.14.16.2) (Tyrosine 3-hydroxylase) (TH).

DBR1_MOUSE
θ value	0.279714 (rank : 9)	NC score	0.054387 (rank : 9)
Query Neighborhood Hits	14	Target Neighborhood Hits	36	Shared Neighborhood Hits	3
SwissProt Accessions	Q923B1, Q8C1T9, Q8C7J7, Q99MT1	Gene names	Dbr1
Domain Architecture	No domain graphic available
Description	Lariat debranching enzyme (EC 3.1.-.-).

AFF4_MOUSE
θ value	1.81305 (rank : 10)	NC score	0.011108 (rank : 11)
Query Neighborhood Hits	14	Target Neighborhood Hits	581	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

KLH23_HUMAN
θ value	2.36792 (rank : 11)	NC score	0.007718 (rank : 13)
Query Neighborhood Hits	14	Target Neighborhood Hits	198	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NBE8, Q8N9B9, Q96FT8	Gene names	KLHL23
Domain Architecture	No domain graphic available
Description	Kelch-like protein 23.

KLH23_MOUSE
θ value	3.0926 (rank : 12)	NC score	0.007472 (rank : 14)
Query Neighborhood Hits	14	Target Neighborhood Hits	188	Shared Neighborhood Hits	3
SwissProt Accessions	Q6GQU2, Q8C840	Gene names	Klhl23
Domain Architecture	No domain graphic available
Description	Kelch-like protein 23.

IRF1_MOUSE
θ value	4.03905 (rank : 13)	NC score	0.010079 (rank : 12)
Query Neighborhood Hits	14	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	P15314	Gene names	Irf1
Domain Architecture
Description	Interferon regulatory factor 1 (IRF-1).

TUSC4_MOUSE
θ value	6.88961 (rank : 14)	NC score	0.011649 (rank : 10)
Query Neighborhood Hits	14	Target Neighborhood Hits	5	Shared Neighborhood Hits	2
SwissProt Accessions	Q9WUE4	Gene names	Tusc4, Nprl2
Domain Architecture
Description	Tumor suppressor candidate 4 (NPR2-like) (Gene 21 protein) (G21 protein).

Hits sorted by NC score

PH4H_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	14
SwissProt Accessions	P16331	Gene names	Pah
Domain Architecture
Description	Phenylalanine-4-hydroxylase (EC 1.14.16.1) (PAH) (Phe-4- monooxygenase).

PH4H_HUMAN
NC score	0.999104 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	14	Target Neighborhood Hits	14	Shared Neighborhood Hits	9
SwissProt Accessions	P00439, Q16717, Q8TC14	Gene names	PAH
Domain Architecture
Description	Phenylalanine-4-hydroxylase (EC 1.14.16.1) (PAH) (Phe-4- monooxygenase).

TPH1_HUMAN
NC score	0.989015 (rank : 3)	θ value	5.78879e-140 (rank : 4)
Query Neighborhood Hits	14	Target Neighborhood Hits	21	Shared Neighborhood Hits	8
SwissProt Accessions	P17752, O95188, O95189, Q16736	Gene names	TPH1, TPH, TRPH
Domain Architecture
Description	Tryptophan 5-hydroxylase 1 (EC 1.14.16.4) (Tryptophan 5-monooxygenase 1).

TPH1_MOUSE
NC score	0.988996 (rank : 4)	θ value	7.56041e-140 (rank : 5)
Query Neighborhood Hits	14	Target Neighborhood Hits	17	Shared Neighborhood Hits	8
SwissProt Accessions	P17532	Gene names	Tph1, Tph
Domain Architecture
Description	Tryptophan 5-hydroxylase 1 (EC 1.14.16.4) (Tryptophan 5-monooxygenase 1).

TPH2_HUMAN
NC score	0.987929 (rank : 5)	θ value	1.05497e-141 (rank : 3)
Query Neighborhood Hits	14	Target Neighborhood Hits	13	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IWU9	Gene names	TPH2, NTPH
Domain Architecture
Description	Tryptophan 5-hydroxylase 2 (EC 1.14.16.4) (Tryptophan 5-monooxygenase 2) (Neuronal tryptophan hydroxylase).

TPH2_MOUSE
NC score	0.987213 (rank : 6)	θ value	2.689e-137 (rank : 6)
Query Neighborhood Hits	14	Target Neighborhood Hits	16	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CGV2	Gene names	Tph2, Ntph
Domain Architecture
Description	Tryptophan 5-hydroxylase 2 (EC 1.14.16.4) (Tryptophan 5-monooxygenase 2) (Neuronal tryptophan hydroxylase).

TY3H_MOUSE
NC score	0.986006 (rank : 7)	θ value	8.97236e-125 (rank : 8)
Query Neighborhood Hits	14	Target Neighborhood Hits	12	Shared Neighborhood Hits	8
SwissProt Accessions	P24529	Gene names	Th
Domain Architecture
Description	Tyrosine 3-monooxygenase (EC 1.14.16.2) (Tyrosine 3-hydroxylase) (TH).

TY3H_HUMAN
NC score	0.985427 (rank : 8)	θ value	1.13238e-127 (rank : 7)
Query Neighborhood Hits	14	Target Neighborhood Hits	13	Shared Neighborhood Hits	8
SwissProt Accessions	P07101, Q15585, Q15588, Q15589	Gene names	TH, TYH
Domain Architecture
Description	Tyrosine 3-monooxygenase (EC 1.14.16.2) (Tyrosine 3-hydroxylase) (TH).

DBR1_MOUSE
NC score	0.054387 (rank : 9)	θ value	0.279714 (rank : 9)
Query Neighborhood Hits	14	Target Neighborhood Hits	36	Shared Neighborhood Hits	3
SwissProt Accessions	Q923B1, Q8C1T9, Q8C7J7, Q99MT1	Gene names	Dbr1
Domain Architecture	No domain graphic available
Description	Lariat debranching enzyme (EC 3.1.-.-).

TUSC4_MOUSE
NC score	0.011649 (rank : 10)	θ value	6.88961 (rank : 14)
Query Neighborhood Hits	14	Target Neighborhood Hits	5	Shared Neighborhood Hits	2
SwissProt Accessions	Q9WUE4	Gene names	Tusc4, Nprl2
Domain Architecture
Description	Tumor suppressor candidate 4 (NPR2-like) (Gene 21 protein) (G21 protein).

AFF4_MOUSE
NC score	0.011108 (rank : 11)	θ value	1.81305 (rank : 10)
Query Neighborhood Hits	14	Target Neighborhood Hits	581	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

IRF1_MOUSE
NC score	0.010079 (rank : 12)	θ value	4.03905 (rank : 13)
Query Neighborhood Hits	14	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	P15314	Gene names	Irf1
Domain Architecture
Description	Interferon regulatory factor 1 (IRF-1).

KLH23_HUMAN
NC score	0.007718 (rank : 13)	θ value	2.36792 (rank : 11)
Query Neighborhood Hits	14	Target Neighborhood Hits	198	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NBE8, Q8N9B9, Q96FT8	Gene names	KLHL23
Domain Architecture	No domain graphic available
Description	Kelch-like protein 23.

KLH23_MOUSE
NC score	0.007472 (rank : 14)	θ value	3.0926 (rank : 12)
Query Neighborhood Hits	14	Target Neighborhood Hits	188	Shared Neighborhood Hits	3
SwissProt Accessions	Q6GQU2, Q8C840	Gene names	Klhl23
Domain Architecture	No domain graphic available
Description	Kelch-like protein 23.