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Network neighborhood for query Sequence : IRF1_MOUSE

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IRF1_MOUSE
SwissProt Accessions	P15314	Gene names	Irf1
Domain Architecture
Description	Interferon regulatory factor 1 (IRF-1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

IRF1_MOUSE
θ value	5.00115e-184 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	27	Target Neighborhood Hits	27	Shared Neighborhood Hits	27
SwissProt Accessions	P15314	Gene names	Irf1
Domain Architecture
Description	Interferon regulatory factor 1 (IRF-1).

IRF1_HUMAN
θ value	7.04359e-154 (rank : 2)	NC score	0.997469 (rank : 2)
Query Neighborhood Hits	27	Target Neighborhood Hits	26	Shared Neighborhood Hits	19
SwissProt Accessions	P10914, Q96GG7	Gene names	IRF1
Domain Architecture
Description	Interferon regulatory factor 1 (IRF-1).

IRF2_HUMAN
θ value	1.15626e-55 (rank : 3)	NC score	0.949493 (rank : 3)
Query Neighborhood Hits	27	Target Neighborhood Hits	35	Shared Neighborhood Hits	18
SwissProt Accessions	P14316, Q96B99	Gene names	IRF2
Domain Architecture
Description	Interferon regulatory factor 2 (IRF-2).

IRF2_MOUSE
θ value	2.18062e-54 (rank : 4)	NC score	0.944771 (rank : 4)
Query Neighborhood Hits	27	Target Neighborhood Hits	49	Shared Neighborhood Hits	18
SwissProt Accessions	P23906	Gene names	Irf2
Domain Architecture
Description	Interferon regulatory factor 2 (IRF-2).

IRF8_HUMAN
θ value	1.24688e-25 (rank : 5)	NC score	0.859782 (rank : 5)
Query Neighborhood Hits	27	Target Neighborhood Hits	25	Shared Neighborhood Hits	18
SwissProt Accessions	Q02556	Gene names	IRF8, ICSBP1
Domain Architecture
Description	Interferon regulatory factor 8 (IRF-8) (Interferon consensus sequence- binding protein) (ICSBP).

IRF4_HUMAN
θ value	2.12685e-25 (rank : 6)	NC score	0.853914 (rank : 8)
Query Neighborhood Hits	27	Target Neighborhood Hits	31	Shared Neighborhood Hits	18
SwissProt Accessions	Q15306, Q99660	Gene names	IRF4, MUM1
Domain Architecture
Description	Interferon regulatory factor 4 (IRF-4) (Lymphocyte-specific interferon regulatory factor) (LSIRF) (NF-EM5) (Multiple myeloma oncogene 1).

IRF8_MOUSE
θ value	2.12685e-25 (rank : 7)	NC score	0.858147 (rank : 6)
Query Neighborhood Hits	27	Target Neighborhood Hits	31	Shared Neighborhood Hits	18
SwissProt Accessions	P23611	Gene names	Irf8, Icsbp, Icsbp1
Domain Architecture
Description	Interferon regulatory factor 8 (IRF-8) (Interferon consensus sequence- binding protein) (ICSBP).

IRF4_MOUSE
θ value	2.77775e-25 (rank : 8)	NC score	0.855247 (rank : 7)
Query Neighborhood Hits	27	Target Neighborhood Hits	27	Shared Neighborhood Hits	18
SwissProt Accessions	Q64287, Q60802	Gene names	Irf4, Spip
Domain Architecture
Description	Interferon regulatory factor 4 (IRF-4) (Lymphocyte-specific interferon regulatory factor) (LSIRF) (NF-EM5) (PU.1 interaction partner) (Transcriptional activator PIP).

IRF5_HUMAN
θ value	8.93572e-24 (rank : 9)	NC score	0.840849 (rank : 10)
Query Neighborhood Hits	27	Target Neighborhood Hits	41	Shared Neighborhood Hits	18
SwissProt Accessions	Q13568, Q9BQF0	Gene names	IRF5
Domain Architecture
Description	Interferon regulatory factor 5 (IRF-5).

IRF5_MOUSE
θ value	8.93572e-24 (rank : 10)	NC score	0.839181 (rank : 11)
Query Neighborhood Hits	27	Target Neighborhood Hits	49	Shared Neighborhood Hits	18
SwissProt Accessions	P56477	Gene names	Irf5
Domain Architecture
Description	Interferon regulatory factor 5 (IRF-5).

IRF6_HUMAN
θ value	7.56453e-23 (rank : 11)	NC score	0.837231 (rank : 12)
Query Neighborhood Hits	27	Target Neighborhood Hits	30	Shared Neighborhood Hits	18
SwissProt Accessions	O14896	Gene names	IRF6
Domain Architecture
Description	Interferon regulatory factor 6 (IRF-6).

IRF6_MOUSE
θ value	7.56453e-23 (rank : 12)	NC score	0.837200 (rank : 13)
Query Neighborhood Hits	27	Target Neighborhood Hits	26	Shared Neighborhood Hits	18
SwissProt Accessions	P97431	Gene names	Irf6
Domain Architecture
Description	Interferon regulatory factor 6 (IRF-6).

IRTF_HUMAN
θ value	9.24701e-21 (rank : 13)	NC score	0.841748 (rank : 9)
Query Neighborhood Hits	27	Target Neighborhood Hits	41	Shared Neighborhood Hits	18
SwissProt Accessions	Q00978	Gene names	ISGF3G, IRF9
Domain Architecture
Description	Transcriptional regulator ISGF3 subunit gamma (Interferon regulatory factor 9) (IRF-9) (IFN-alpha-responsive transcription factor subunit) (Interferon-stimulated gene factor 3 gamma) (ISGF3 p48 subunit) (ISGF- 3 gamma).

IRTF_MOUSE
θ value	6.62687e-19 (rank : 14)	NC score	0.833975 (rank : 14)
Query Neighborhood Hits	27	Target Neighborhood Hits	26	Shared Neighborhood Hits	18
SwissProt Accessions	Q61179	Gene names	Isgf3g
Domain Architecture
Description	Transcriptional regulator ISGF3 subunit gamma (IFN-alpha-responsive transcription factor subunit) (Interferon-stimulated gene factor 3 gamma) (ISGF3 p48 subunit) (ISGF-3 gamma).

IRF3_HUMAN
θ value	3.40345e-15 (rank : 15)	NC score	0.783154 (rank : 16)
Query Neighborhood Hits	27	Target Neighborhood Hits	129	Shared Neighborhood Hits	18
SwissProt Accessions	Q14653	Gene names	IRF3
Domain Architecture
Description	Interferon regulatory factor 3 (IRF-3).

IRF3_MOUSE
θ value	4.44505e-15 (rank : 16)	NC score	0.793436 (rank : 15)
Query Neighborhood Hits	27	Target Neighborhood Hits	25	Shared Neighborhood Hits	18
SwissProt Accessions	P70671	Gene names	Irf3
Domain Architecture
Description	Interferon regulatory factor 3 (IRF-3).

IRF7_MOUSE
θ value	1.33837e-11 (rank : 17)	NC score	0.767514 (rank : 17)
Query Neighborhood Hits	27	Target Neighborhood Hits	34	Shared Neighborhood Hits	18
SwissProt Accessions	P70434	Gene names	Irf7
Domain Architecture
Description	Interferon regulatory factor 7 (IRF-7).

IRF7_HUMAN
θ value	5.62301e-10 (rank : 18)	NC score	0.739868 (rank : 18)
Query Neighborhood Hits	27	Target Neighborhood Hits	73	Shared Neighborhood Hits	18
SwissProt Accessions	Q92985, O00331, O00332, O00333, O75924	Gene names	IRF7
Domain Architecture
Description	Interferon regulatory factor 7 (IRF-7).

NPAL2_MOUSE
θ value	0.813845 (rank : 19)	NC score	0.023938 (rank : 21)
Query Neighborhood Hits	27	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	Q91WC7, Q8CC43	Gene names	Npal2, Nipal2
Domain Architecture	No domain graphic available
Description	NIPA-like protein 2.

SDPR_MOUSE
θ value	1.38821 (rank : 20)	NC score	0.022262 (rank : 22)
Query Neighborhood Hits	27	Target Neighborhood Hits	485	Shared Neighborhood Hits	3
SwissProt Accessions	Q63918, Q3V1P6, Q78EC3, Q8CBT4	Gene names	Sdpr, Sdr
Domain Architecture	No domain graphic available
Description	Serum deprivation-response protein (Phosphatidylserine-binding protein).

CNOT3_HUMAN
θ value	2.36792 (rank : 21)	NC score	0.025209 (rank : 19)
Query Neighborhood Hits	27	Target Neighborhood Hits	425	Shared Neighborhood Hits	4
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

CNOT3_MOUSE
θ value	2.36792 (rank : 22)	NC score	0.024396 (rank : 20)
Query Neighborhood Hits	27	Target Neighborhood Hits	504	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K0V4	Gene names	Cnot3, Not3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

PARG_MOUSE
θ value	3.0926 (rank : 23)	NC score	0.018539 (rank : 23)
Query Neighborhood Hits	27	Target Neighborhood Hits	54	Shared Neighborhood Hits	2
SwissProt Accessions	O88622, Q80YQ6, Q8CB72	Gene names	Parg
Domain Architecture	No domain graphic available
Description	Poly(ADP-ribose) glycohydrolase (EC 3.2.1.143).

MLL3_MOUSE
θ value	4.03905 (rank : 24)	NC score	0.004988 (rank : 26)
Query Neighborhood Hits	27	Target Neighborhood Hits	1399	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

PH4H_MOUSE
θ value	4.03905 (rank : 25)	NC score	0.010079 (rank : 24)
Query Neighborhood Hits	27	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	P16331	Gene names	Pah
Domain Architecture
Description	Phenylalanine-4-hydroxylase (EC 1.14.16.1) (PAH) (Phe-4- monooxygenase).

LMX1B_HUMAN
θ value	5.27518 (rank : 26)	NC score	0.002970 (rank : 27)
Query Neighborhood Hits	27	Target Neighborhood Hits	404	Shared Neighborhood Hits	2
SwissProt Accessions	O60663, O75463	Gene names	LMX1B
Domain Architecture
Description	LIM homeobox transcription factor 1 beta (LIM/homeobox protein LMX1B) (LIM-homeobox protein 1.2) (LMX-1.2).

ZFYV9_HUMAN
θ value	8.99809 (rank : 27)	NC score	0.006363 (rank : 25)
Query Neighborhood Hits	27	Target Neighborhood Hits	134	Shared Neighborhood Hits	2
SwissProt Accessions	O95405, Q9UNE1, Q9Y5R7	Gene names	ZFYVE9, MADHIP, SARA, SMADIP
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 9 (Mothers against decapentaplegic homolog-interacting protein) (Madh-interacting protein) (Smad anchor for receptor activation) (Receptor activation anchor) (hSARA) (Novel serine protease) (NSP).

Hits sorted by NC score

IRF1_MOUSE
NC score	0.999962 (rank : 1)	θ value	5.00115e-184 (rank : 1)
Query Neighborhood Hits	27	Target Neighborhood Hits	27	Shared Neighborhood Hits	27
SwissProt Accessions	P15314	Gene names	Irf1
Domain Architecture
Description	Interferon regulatory factor 1 (IRF-1).

IRF1_HUMAN
NC score	0.997469 (rank : 2)	θ value	7.04359e-154 (rank : 2)
Query Neighborhood Hits	27	Target Neighborhood Hits	26	Shared Neighborhood Hits	19
SwissProt Accessions	P10914, Q96GG7	Gene names	IRF1
Domain Architecture
Description	Interferon regulatory factor 1 (IRF-1).

IRF2_HUMAN
NC score	0.949493 (rank : 3)	θ value	1.15626e-55 (rank : 3)
Query Neighborhood Hits	27	Target Neighborhood Hits	35	Shared Neighborhood Hits	18
SwissProt Accessions	P14316, Q96B99	Gene names	IRF2
Domain Architecture
Description	Interferon regulatory factor 2 (IRF-2).

IRF2_MOUSE
NC score	0.944771 (rank : 4)	θ value	2.18062e-54 (rank : 4)
Query Neighborhood Hits	27	Target Neighborhood Hits	49	Shared Neighborhood Hits	18
SwissProt Accessions	P23906	Gene names	Irf2
Domain Architecture
Description	Interferon regulatory factor 2 (IRF-2).

IRF8_HUMAN
NC score	0.859782 (rank : 5)	θ value	1.24688e-25 (rank : 5)
Query Neighborhood Hits	27	Target Neighborhood Hits	25	Shared Neighborhood Hits	18
SwissProt Accessions	Q02556	Gene names	IRF8, ICSBP1
Domain Architecture
Description	Interferon regulatory factor 8 (IRF-8) (Interferon consensus sequence- binding protein) (ICSBP).

IRF8_MOUSE
NC score	0.858147 (rank : 6)	θ value	2.12685e-25 (rank : 7)
Query Neighborhood Hits	27	Target Neighborhood Hits	31	Shared Neighborhood Hits	18
SwissProt Accessions	P23611	Gene names	Irf8, Icsbp, Icsbp1
Domain Architecture
Description	Interferon regulatory factor 8 (IRF-8) (Interferon consensus sequence- binding protein) (ICSBP).

IRF4_MOUSE
NC score	0.855247 (rank : 7)	θ value	2.77775e-25 (rank : 8)
Query Neighborhood Hits	27	Target Neighborhood Hits	27	Shared Neighborhood Hits	18
SwissProt Accessions	Q64287, Q60802	Gene names	Irf4, Spip
Domain Architecture
Description	Interferon regulatory factor 4 (IRF-4) (Lymphocyte-specific interferon regulatory factor) (LSIRF) (NF-EM5) (PU.1 interaction partner) (Transcriptional activator PIP).

IRF4_HUMAN
NC score	0.853914 (rank : 8)	θ value	2.12685e-25 (rank : 6)
Query Neighborhood Hits	27	Target Neighborhood Hits	31	Shared Neighborhood Hits	18
SwissProt Accessions	Q15306, Q99660	Gene names	IRF4, MUM1
Domain Architecture
Description	Interferon regulatory factor 4 (IRF-4) (Lymphocyte-specific interferon regulatory factor) (LSIRF) (NF-EM5) (Multiple myeloma oncogene 1).

IRTF_HUMAN
NC score	0.841748 (rank : 9)	θ value	9.24701e-21 (rank : 13)
Query Neighborhood Hits	27	Target Neighborhood Hits	41	Shared Neighborhood Hits	18
SwissProt Accessions	Q00978	Gene names	ISGF3G, IRF9
Domain Architecture
Description	Transcriptional regulator ISGF3 subunit gamma (Interferon regulatory factor 9) (IRF-9) (IFN-alpha-responsive transcription factor subunit) (Interferon-stimulated gene factor 3 gamma) (ISGF3 p48 subunit) (ISGF- 3 gamma).

IRF5_HUMAN
NC score	0.840849 (rank : 10)	θ value	8.93572e-24 (rank : 9)
Query Neighborhood Hits	27	Target Neighborhood Hits	41	Shared Neighborhood Hits	18
SwissProt Accessions	Q13568, Q9BQF0	Gene names	IRF5
Domain Architecture
Description	Interferon regulatory factor 5 (IRF-5).

IRF5_MOUSE
NC score	0.839181 (rank : 11)	θ value	8.93572e-24 (rank : 10)
Query Neighborhood Hits	27	Target Neighborhood Hits	49	Shared Neighborhood Hits	18
SwissProt Accessions	P56477	Gene names	Irf5
Domain Architecture
Description	Interferon regulatory factor 5 (IRF-5).

IRF6_HUMAN
NC score	0.837231 (rank : 12)	θ value	7.56453e-23 (rank : 11)
Query Neighborhood Hits	27	Target Neighborhood Hits	30	Shared Neighborhood Hits	18
SwissProt Accessions	O14896	Gene names	IRF6
Domain Architecture
Description	Interferon regulatory factor 6 (IRF-6).

IRF6_MOUSE
NC score	0.837200 (rank : 13)	θ value	7.56453e-23 (rank : 12)
Query Neighborhood Hits	27	Target Neighborhood Hits	26	Shared Neighborhood Hits	18
SwissProt Accessions	P97431	Gene names	Irf6
Domain Architecture
Description	Interferon regulatory factor 6 (IRF-6).

IRTF_MOUSE
NC score	0.833975 (rank : 14)	θ value	6.62687e-19 (rank : 14)
Query Neighborhood Hits	27	Target Neighborhood Hits	26	Shared Neighborhood Hits	18
SwissProt Accessions	Q61179	Gene names	Isgf3g
Domain Architecture
Description	Transcriptional regulator ISGF3 subunit gamma (IFN-alpha-responsive transcription factor subunit) (Interferon-stimulated gene factor 3 gamma) (ISGF3 p48 subunit) (ISGF-3 gamma).

IRF3_MOUSE
NC score	0.793436 (rank : 15)	θ value	4.44505e-15 (rank : 16)
Query Neighborhood Hits	27	Target Neighborhood Hits	25	Shared Neighborhood Hits	18
SwissProt Accessions	P70671	Gene names	Irf3
Domain Architecture
Description	Interferon regulatory factor 3 (IRF-3).

IRF3_HUMAN
NC score	0.783154 (rank : 16)	θ value	3.40345e-15 (rank : 15)
Query Neighborhood Hits	27	Target Neighborhood Hits	129	Shared Neighborhood Hits	18
SwissProt Accessions	Q14653	Gene names	IRF3
Domain Architecture
Description	Interferon regulatory factor 3 (IRF-3).

IRF7_MOUSE
NC score	0.767514 (rank : 17)	θ value	1.33837e-11 (rank : 17)
Query Neighborhood Hits	27	Target Neighborhood Hits	34	Shared Neighborhood Hits	18
SwissProt Accessions	P70434	Gene names	Irf7
Domain Architecture
Description	Interferon regulatory factor 7 (IRF-7).

IRF7_HUMAN
NC score	0.739868 (rank : 18)	θ value	5.62301e-10 (rank : 18)
Query Neighborhood Hits	27	Target Neighborhood Hits	73	Shared Neighborhood Hits	18
SwissProt Accessions	Q92985, O00331, O00332, O00333, O75924	Gene names	IRF7
Domain Architecture
Description	Interferon regulatory factor 7 (IRF-7).

CNOT3_HUMAN
NC score	0.025209 (rank : 19)	θ value	2.36792 (rank : 21)
Query Neighborhood Hits	27	Target Neighborhood Hits	425	Shared Neighborhood Hits	4
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

CNOT3_MOUSE
NC score	0.024396 (rank : 20)	θ value	2.36792 (rank : 22)
Query Neighborhood Hits	27	Target Neighborhood Hits	504	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K0V4	Gene names	Cnot3, Not3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

NPAL2_MOUSE
NC score	0.023938 (rank : 21)	θ value	0.813845 (rank : 19)
Query Neighborhood Hits	27	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	Q91WC7, Q8CC43	Gene names	Npal2, Nipal2
Domain Architecture	No domain graphic available
Description	NIPA-like protein 2.

SDPR_MOUSE
NC score	0.022262 (rank : 22)	θ value	1.38821 (rank : 20)
Query Neighborhood Hits	27	Target Neighborhood Hits	485	Shared Neighborhood Hits	3
SwissProt Accessions	Q63918, Q3V1P6, Q78EC3, Q8CBT4	Gene names	Sdpr, Sdr
Domain Architecture	No domain graphic available
Description	Serum deprivation-response protein (Phosphatidylserine-binding protein).

PARG_MOUSE
NC score	0.018539 (rank : 23)	θ value	3.0926 (rank : 23)
Query Neighborhood Hits	27	Target Neighborhood Hits	54	Shared Neighborhood Hits	2
SwissProt Accessions	O88622, Q80YQ6, Q8CB72	Gene names	Parg
Domain Architecture	No domain graphic available
Description	Poly(ADP-ribose) glycohydrolase (EC 3.2.1.143).

PH4H_MOUSE
NC score	0.010079 (rank : 24)	θ value	4.03905 (rank : 25)
Query Neighborhood Hits	27	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	P16331	Gene names	Pah
Domain Architecture
Description	Phenylalanine-4-hydroxylase (EC 1.14.16.1) (PAH) (Phe-4- monooxygenase).

ZFYV9_HUMAN
NC score	0.006363 (rank : 25)	θ value	8.99809 (rank : 27)
Query Neighborhood Hits	27	Target Neighborhood Hits	134	Shared Neighborhood Hits	2
SwissProt Accessions	O95405, Q9UNE1, Q9Y5R7	Gene names	ZFYVE9, MADHIP, SARA, SMADIP
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 9 (Mothers against decapentaplegic homolog-interacting protein) (Madh-interacting protein) (Smad anchor for receptor activation) (Receptor activation anchor) (hSARA) (Novel serine protease) (NSP).

MLL3_MOUSE
NC score	0.004988 (rank : 26)	θ value	4.03905 (rank : 24)
Query Neighborhood Hits	27	Target Neighborhood Hits	1399	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

LMX1B_HUMAN
NC score	0.002970 (rank : 27)	θ value	5.27518 (rank : 26)
Query Neighborhood Hits	27	Target Neighborhood Hits	404	Shared Neighborhood Hits	2
SwissProt Accessions	O60663, O75463	Gene names	LMX1B
Domain Architecture
Description	LIM homeobox transcription factor 1 beta (LIM/homeobox protein LMX1B) (LIM-homeobox protein 1.2) (LMX-1.2).