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Network neighborhood for query Sequence : IRF3_MOUSE

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IRF3_MOUSE
SwissProt Accessions	P70671	Gene names	Irf3
Domain Architecture
Description	Interferon regulatory factor 3 (IRF-3).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

IRF3_MOUSE
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	25	Target Neighborhood Hits	25	Shared Neighborhood Hits	25
SwissProt Accessions	P70671	Gene names	Irf3
Domain Architecture
Description	Interferon regulatory factor 3 (IRF-3).

IRF3_HUMAN
θ value	9.78303e-172 (rank : 2)	NC score	0.980458 (rank : 2)
Query Neighborhood Hits	25	Target Neighborhood Hits	129	Shared Neighborhood Hits	18
SwissProt Accessions	Q14653	Gene names	IRF3
Domain Architecture
Description	Interferon regulatory factor 3 (IRF-3).

IRF5_HUMAN
θ value	7.52953e-39 (rank : 3)	NC score	0.902699 (rank : 3)
Query Neighborhood Hits	25	Target Neighborhood Hits	41	Shared Neighborhood Hits	19
SwissProt Accessions	Q13568, Q9BQF0	Gene names	IRF5
Domain Architecture
Description	Interferon regulatory factor 5 (IRF-5).

IRF5_MOUSE
θ value	4.88048e-38 (rank : 4)	NC score	0.902641 (rank : 4)
Query Neighborhood Hits	25	Target Neighborhood Hits	49	Shared Neighborhood Hits	18
SwissProt Accessions	P56477	Gene names	Irf5
Domain Architecture
Description	Interferon regulatory factor 5 (IRF-5).

IRF7_MOUSE
θ value	1.08726e-37 (rank : 5)	NC score	0.899758 (rank : 5)
Query Neighborhood Hits	25	Target Neighborhood Hits	34	Shared Neighborhood Hits	18
SwissProt Accessions	P70434	Gene names	Irf7
Domain Architecture
Description	Interferon regulatory factor 7 (IRF-7).

IRF6_HUMAN
θ value	2.77131e-33 (rank : 6)	NC score	0.894368 (rank : 6)
Query Neighborhood Hits	25	Target Neighborhood Hits	30	Shared Neighborhood Hits	18
SwissProt Accessions	O14896	Gene names	IRF6
Domain Architecture
Description	Interferon regulatory factor 6 (IRF-6).

IRF6_MOUSE
θ value	1.37539e-32 (rank : 7)	NC score	0.893689 (rank : 7)
Query Neighborhood Hits	25	Target Neighborhood Hits	26	Shared Neighborhood Hits	18
SwissProt Accessions	P97431	Gene names	Irf6
Domain Architecture
Description	Interferon regulatory factor 6 (IRF-6).

IRF4_HUMAN
θ value	3.06405e-32 (rank : 8)	NC score	0.880277 (rank : 8)
Query Neighborhood Hits	25	Target Neighborhood Hits	31	Shared Neighborhood Hits	18
SwissProt Accessions	Q15306, Q99660	Gene names	IRF4, MUM1
Domain Architecture
Description	Interferon regulatory factor 4 (IRF-4) (Lymphocyte-specific interferon regulatory factor) (LSIRF) (NF-EM5) (Multiple myeloma oncogene 1).

IRF4_MOUSE
θ value	2.86786e-30 (rank : 9)	NC score	0.879173 (rank : 9)
Query Neighborhood Hits	25	Target Neighborhood Hits	27	Shared Neighborhood Hits	18
SwissProt Accessions	Q64287, Q60802	Gene names	Irf4, Spip
Domain Architecture
Description	Interferon regulatory factor 4 (IRF-4) (Lymphocyte-specific interferon regulatory factor) (LSIRF) (NF-EM5) (PU.1 interaction partner) (Transcriptional activator PIP).

IRF8_HUMAN
θ value	7.30988e-26 (rank : 10)	NC score	0.868473 (rank : 10)
Query Neighborhood Hits	25	Target Neighborhood Hits	25	Shared Neighborhood Hits	18
SwissProt Accessions	Q02556	Gene names	IRF8, ICSBP1
Domain Architecture
Description	Interferon regulatory factor 8 (IRF-8) (Interferon consensus sequence- binding protein) (ICSBP).

IRF8_MOUSE
θ value	8.08199e-25 (rank : 11)	NC score	0.864625 (rank : 12)
Query Neighborhood Hits	25	Target Neighborhood Hits	31	Shared Neighborhood Hits	18
SwissProt Accessions	P23611	Gene names	Irf8, Icsbp, Icsbp1
Domain Architecture
Description	Interferon regulatory factor 8 (IRF-8) (Interferon consensus sequence- binding protein) (ICSBP).

IRF7_HUMAN
θ value	3.17815e-21 (rank : 12)	NC score	0.866294 (rank : 11)
Query Neighborhood Hits	25	Target Neighborhood Hits	73	Shared Neighborhood Hits	18
SwissProt Accessions	Q92985, O00331, O00332, O00333, O75924	Gene names	IRF7
Domain Architecture
Description	Interferon regulatory factor 7 (IRF-7).

IRTF_HUMAN
θ value	3.17815e-21 (rank : 13)	NC score	0.849513 (rank : 13)
Query Neighborhood Hits	25	Target Neighborhood Hits	41	Shared Neighborhood Hits	18
SwissProt Accessions	Q00978	Gene names	ISGF3G, IRF9
Domain Architecture
Description	Transcriptional regulator ISGF3 subunit gamma (Interferon regulatory factor 9) (IRF-9) (IFN-alpha-responsive transcription factor subunit) (Interferon-stimulated gene factor 3 gamma) (ISGF3 p48 subunit) (ISGF- 3 gamma).

IRTF_MOUSE
θ value	8.10077e-17 (rank : 14)	NC score	0.818865 (rank : 14)
Query Neighborhood Hits	25	Target Neighborhood Hits	26	Shared Neighborhood Hits	18
SwissProt Accessions	Q61179	Gene names	Isgf3g
Domain Architecture
Description	Transcriptional regulator ISGF3 subunit gamma (IFN-alpha-responsive transcription factor subunit) (Interferon-stimulated gene factor 3 gamma) (ISGF3 p48 subunit) (ISGF-3 gamma).

IRF1_HUMAN
θ value	3.40345e-15 (rank : 15)	NC score	0.796972 (rank : 15)
Query Neighborhood Hits	25	Target Neighborhood Hits	26	Shared Neighborhood Hits	18
SwissProt Accessions	P10914, Q96GG7	Gene names	IRF1
Domain Architecture
Description	Interferon regulatory factor 1 (IRF-1).

IRF1_MOUSE
θ value	4.44505e-15 (rank : 16)	NC score	0.793436 (rank : 16)
Query Neighborhood Hits	25	Target Neighborhood Hits	27	Shared Neighborhood Hits	18
SwissProt Accessions	P15314	Gene names	Irf1
Domain Architecture
Description	Interferon regulatory factor 1 (IRF-1).

IRF2_HUMAN
θ value	1.29331e-14 (rank : 17)	NC score	0.789742 (rank : 17)
Query Neighborhood Hits	25	Target Neighborhood Hits	35	Shared Neighborhood Hits	18
SwissProt Accessions	P14316, Q96B99	Gene names	IRF2
Domain Architecture
Description	Interferon regulatory factor 2 (IRF-2).

IRF2_MOUSE
θ value	2.20605e-14 (rank : 18)	NC score	0.786874 (rank : 18)
Query Neighborhood Hits	25	Target Neighborhood Hits	49	Shared Neighborhood Hits	18
SwissProt Accessions	P23906	Gene names	Irf2
Domain Architecture
Description	Interferon regulatory factor 2 (IRF-2).

LMO7_HUMAN
θ value	3.0926 (rank : 19)	NC score	0.015671 (rank : 21)
Query Neighborhood Hits	25	Target Neighborhood Hits	507	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WWI1, O15462, O95346, Q9UKC1, Q9UQM5, Q9Y6A7	Gene names	LMO7, FBX20, FBXO20, KIAA0858
Domain Architecture
Description	LIM domain only protein 7 (LOMP) (F-box only protein 20).

MLL3_HUMAN
θ value	4.03905 (rank : 20)	NC score	0.006425 (rank : 24)
Query Neighborhood Hits	25	Target Neighborhood Hits	1644	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

NRF1_HUMAN
θ value	5.27518 (rank : 21)	NC score	0.024015 (rank : 19)
Query Neighborhood Hits	25	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q16656, Q15305	Gene names	NRF1
Domain Architecture	No domain graphic available
Description	Nuclear respiratory factor 1 (NRF-1) (Alpha palindromic-binding protein) (Alpha-pal).

NRF1_MOUSE
θ value	5.27518 (rank : 22)	NC score	0.024013 (rank : 20)
Query Neighborhood Hits	25	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q9WU00	Gene names	Nrf1
Domain Architecture	No domain graphic available
Description	Nuclear respiratory factor 1 (NRF-1) (Alpha palindromic-binding protein) (Alpha-pal).

ARSA_MOUSE
θ value	6.88961 (rank : 23)	NC score	0.007236 (rank : 23)
Query Neighborhood Hits	25	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	P50428	Gene names	Arsa, As2
Domain Architecture
Description	Arylsulfatase A precursor (EC 3.1.6.8) (ASA) (Cerebroside-sulfatase).

PTPRO_HUMAN
θ value	6.88961 (rank : 24)	NC score	0.003531 (rank : 25)
Query Neighborhood Hits	25	Target Neighborhood Hits	139	Shared Neighborhood Hits	2
SwissProt Accessions	Q16827, Q13101	Gene names	PTPRO, GLEPP1, PTPU2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase O precursor (EC 3.1.3.48) (Glomerular epithelial protein 1) (Protein tyrosine phosphatase U2) (PTPase U2) (PTP-U2).

ZC3H6_MOUSE
θ value	6.88961 (rank : 25)	NC score	0.008299 (rank : 22)
Query Neighborhood Hits	25	Target Neighborhood Hits	239	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BYK8, Q80UK3, Q8C1H1, Q9D604	Gene names	Zc3h6, Zc3hdc6
Domain Architecture
Description	Zinc finger CCCH domain-containing protein 6.

Hits sorted by NC score

IRF3_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	25	Target Neighborhood Hits	25	Shared Neighborhood Hits	25
SwissProt Accessions	P70671	Gene names	Irf3
Domain Architecture
Description	Interferon regulatory factor 3 (IRF-3).

IRF3_HUMAN
NC score	0.980458 (rank : 2)	θ value	9.78303e-172 (rank : 2)
Query Neighborhood Hits	25	Target Neighborhood Hits	129	Shared Neighborhood Hits	18
SwissProt Accessions	Q14653	Gene names	IRF3
Domain Architecture
Description	Interferon regulatory factor 3 (IRF-3).

IRF5_HUMAN
NC score	0.902699 (rank : 3)	θ value	7.52953e-39 (rank : 3)
Query Neighborhood Hits	25	Target Neighborhood Hits	41	Shared Neighborhood Hits	19
SwissProt Accessions	Q13568, Q9BQF0	Gene names	IRF5
Domain Architecture
Description	Interferon regulatory factor 5 (IRF-5).

IRF5_MOUSE
NC score	0.902641 (rank : 4)	θ value	4.88048e-38 (rank : 4)
Query Neighborhood Hits	25	Target Neighborhood Hits	49	Shared Neighborhood Hits	18
SwissProt Accessions	P56477	Gene names	Irf5
Domain Architecture
Description	Interferon regulatory factor 5 (IRF-5).

IRF7_MOUSE
NC score	0.899758 (rank : 5)	θ value	1.08726e-37 (rank : 5)
Query Neighborhood Hits	25	Target Neighborhood Hits	34	Shared Neighborhood Hits	18
SwissProt Accessions	P70434	Gene names	Irf7
Domain Architecture
Description	Interferon regulatory factor 7 (IRF-7).

IRF6_HUMAN
NC score	0.894368 (rank : 6)	θ value	2.77131e-33 (rank : 6)
Query Neighborhood Hits	25	Target Neighborhood Hits	30	Shared Neighborhood Hits	18
SwissProt Accessions	O14896	Gene names	IRF6
Domain Architecture
Description	Interferon regulatory factor 6 (IRF-6).

IRF6_MOUSE
NC score	0.893689 (rank : 7)	θ value	1.37539e-32 (rank : 7)
Query Neighborhood Hits	25	Target Neighborhood Hits	26	Shared Neighborhood Hits	18
SwissProt Accessions	P97431	Gene names	Irf6
Domain Architecture
Description	Interferon regulatory factor 6 (IRF-6).

IRF4_HUMAN
NC score	0.880277 (rank : 8)	θ value	3.06405e-32 (rank : 8)
Query Neighborhood Hits	25	Target Neighborhood Hits	31	Shared Neighborhood Hits	18
SwissProt Accessions	Q15306, Q99660	Gene names	IRF4, MUM1
Domain Architecture
Description	Interferon regulatory factor 4 (IRF-4) (Lymphocyte-specific interferon regulatory factor) (LSIRF) (NF-EM5) (Multiple myeloma oncogene 1).

IRF4_MOUSE
NC score	0.879173 (rank : 9)	θ value	2.86786e-30 (rank : 9)
Query Neighborhood Hits	25	Target Neighborhood Hits	27	Shared Neighborhood Hits	18
SwissProt Accessions	Q64287, Q60802	Gene names	Irf4, Spip
Domain Architecture
Description	Interferon regulatory factor 4 (IRF-4) (Lymphocyte-specific interferon regulatory factor) (LSIRF) (NF-EM5) (PU.1 interaction partner) (Transcriptional activator PIP).

IRF8_HUMAN
NC score	0.868473 (rank : 10)	θ value	7.30988e-26 (rank : 10)
Query Neighborhood Hits	25	Target Neighborhood Hits	25	Shared Neighborhood Hits	18
SwissProt Accessions	Q02556	Gene names	IRF8, ICSBP1
Domain Architecture
Description	Interferon regulatory factor 8 (IRF-8) (Interferon consensus sequence- binding protein) (ICSBP).

IRF7_HUMAN
NC score	0.866294 (rank : 11)	θ value	3.17815e-21 (rank : 12)
Query Neighborhood Hits	25	Target Neighborhood Hits	73	Shared Neighborhood Hits	18
SwissProt Accessions	Q92985, O00331, O00332, O00333, O75924	Gene names	IRF7
Domain Architecture
Description	Interferon regulatory factor 7 (IRF-7).

IRF8_MOUSE
NC score	0.864625 (rank : 12)	θ value	8.08199e-25 (rank : 11)
Query Neighborhood Hits	25	Target Neighborhood Hits	31	Shared Neighborhood Hits	18
SwissProt Accessions	P23611	Gene names	Irf8, Icsbp, Icsbp1
Domain Architecture
Description	Interferon regulatory factor 8 (IRF-8) (Interferon consensus sequence- binding protein) (ICSBP).

IRTF_HUMAN
NC score	0.849513 (rank : 13)	θ value	3.17815e-21 (rank : 13)
Query Neighborhood Hits	25	Target Neighborhood Hits	41	Shared Neighborhood Hits	18
SwissProt Accessions	Q00978	Gene names	ISGF3G, IRF9
Domain Architecture
Description	Transcriptional regulator ISGF3 subunit gamma (Interferon regulatory factor 9) (IRF-9) (IFN-alpha-responsive transcription factor subunit) (Interferon-stimulated gene factor 3 gamma) (ISGF3 p48 subunit) (ISGF- 3 gamma).

IRTF_MOUSE
NC score	0.818865 (rank : 14)	θ value	8.10077e-17 (rank : 14)
Query Neighborhood Hits	25	Target Neighborhood Hits	26	Shared Neighborhood Hits	18
SwissProt Accessions	Q61179	Gene names	Isgf3g
Domain Architecture
Description	Transcriptional regulator ISGF3 subunit gamma (IFN-alpha-responsive transcription factor subunit) (Interferon-stimulated gene factor 3 gamma) (ISGF3 p48 subunit) (ISGF-3 gamma).

IRF1_HUMAN
NC score	0.796972 (rank : 15)	θ value	3.40345e-15 (rank : 15)
Query Neighborhood Hits	25	Target Neighborhood Hits	26	Shared Neighborhood Hits	18
SwissProt Accessions	P10914, Q96GG7	Gene names	IRF1
Domain Architecture
Description	Interferon regulatory factor 1 (IRF-1).

IRF1_MOUSE
NC score	0.793436 (rank : 16)	θ value	4.44505e-15 (rank : 16)
Query Neighborhood Hits	25	Target Neighborhood Hits	27	Shared Neighborhood Hits	18
SwissProt Accessions	P15314	Gene names	Irf1
Domain Architecture
Description	Interferon regulatory factor 1 (IRF-1).

IRF2_HUMAN
NC score	0.789742 (rank : 17)	θ value	1.29331e-14 (rank : 17)
Query Neighborhood Hits	25	Target Neighborhood Hits	35	Shared Neighborhood Hits	18
SwissProt Accessions	P14316, Q96B99	Gene names	IRF2
Domain Architecture
Description	Interferon regulatory factor 2 (IRF-2).

IRF2_MOUSE
NC score	0.786874 (rank : 18)	θ value	2.20605e-14 (rank : 18)
Query Neighborhood Hits	25	Target Neighborhood Hits	49	Shared Neighborhood Hits	18
SwissProt Accessions	P23906	Gene names	Irf2
Domain Architecture
Description	Interferon regulatory factor 2 (IRF-2).

NRF1_HUMAN
NC score	0.024015 (rank : 19)	θ value	5.27518 (rank : 21)
Query Neighborhood Hits	25	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q16656, Q15305	Gene names	NRF1
Domain Architecture	No domain graphic available
Description	Nuclear respiratory factor 1 (NRF-1) (Alpha palindromic-binding protein) (Alpha-pal).

NRF1_MOUSE
NC score	0.024013 (rank : 20)	θ value	5.27518 (rank : 22)
Query Neighborhood Hits	25	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q9WU00	Gene names	Nrf1
Domain Architecture	No domain graphic available
Description	Nuclear respiratory factor 1 (NRF-1) (Alpha palindromic-binding protein) (Alpha-pal).

LMO7_HUMAN
NC score	0.015671 (rank : 21)	θ value	3.0926 (rank : 19)
Query Neighborhood Hits	25	Target Neighborhood Hits	507	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WWI1, O15462, O95346, Q9UKC1, Q9UQM5, Q9Y6A7	Gene names	LMO7, FBX20, FBXO20, KIAA0858
Domain Architecture
Description	LIM domain only protein 7 (LOMP) (F-box only protein 20).

ZC3H6_MOUSE
NC score	0.008299 (rank : 22)	θ value	6.88961 (rank : 25)
Query Neighborhood Hits	25	Target Neighborhood Hits	239	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BYK8, Q80UK3, Q8C1H1, Q9D604	Gene names	Zc3h6, Zc3hdc6
Domain Architecture
Description	Zinc finger CCCH domain-containing protein 6.

ARSA_MOUSE
NC score	0.007236 (rank : 23)	θ value	6.88961 (rank : 23)
Query Neighborhood Hits	25	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	P50428	Gene names	Arsa, As2
Domain Architecture
Description	Arylsulfatase A precursor (EC 3.1.6.8) (ASA) (Cerebroside-sulfatase).

MLL3_HUMAN
NC score	0.006425 (rank : 24)	θ value	4.03905 (rank : 20)
Query Neighborhood Hits	25	Target Neighborhood Hits	1644	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

PTPRO_HUMAN
NC score	0.003531 (rank : 25)	θ value	6.88961 (rank : 24)
Query Neighborhood Hits	25	Target Neighborhood Hits	139	Shared Neighborhood Hits	2
SwissProt Accessions	Q16827, Q13101	Gene names	PTPRO, GLEPP1, PTPU2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase O precursor (EC 3.1.3.48) (Glomerular epithelial protein 1) (Protein tyrosine phosphatase U2) (PTPase U2) (PTP-U2).