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Network neighborhood for query Sequence : IRTF_HUMAN

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IRTF_HUMAN
SwissProt Accessions	Q00978	Gene names	ISGF3G, IRF9
Domain Architecture
Description	Transcriptional regulator ISGF3 subunit gamma (Interferon regulatory factor 9) (IRF-9) (IFN-alpha-responsive transcription factor subunit) (Interferon-stimulated gene factor 3 gamma) (ISGF3 p48 subunit) (ISGF- 3 gamma).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

IRTF_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	41	Target Neighborhood Hits	41	Shared Neighborhood Hits	41
SwissProt Accessions	Q00978	Gene names	ISGF3G, IRF9
Domain Architecture
Description	Transcriptional regulator ISGF3 subunit gamma (Interferon regulatory factor 9) (IRF-9) (IFN-alpha-responsive transcription factor subunit) (Interferon-stimulated gene factor 3 gamma) (ISGF3 p48 subunit) (ISGF- 3 gamma).

IRTF_MOUSE
θ value	2.85966e-155 (rank : 2)	NC score	0.991530 (rank : 2)
Query Neighborhood Hits	41	Target Neighborhood Hits	26	Shared Neighborhood Hits	20
SwissProt Accessions	Q61179	Gene names	Isgf3g
Domain Architecture
Description	Transcriptional regulator ISGF3 subunit gamma (IFN-alpha-responsive transcription factor subunit) (Interferon-stimulated gene factor 3 gamma) (ISGF3 p48 subunit) (ISGF-3 gamma).

IRF8_MOUSE
θ value	8.55514e-59 (rank : 3)	NC score	0.951543 (rank : 3)
Query Neighborhood Hits	41	Target Neighborhood Hits	31	Shared Neighborhood Hits	18
SwissProt Accessions	P23611	Gene names	Irf8, Icsbp, Icsbp1
Domain Architecture
Description	Interferon regulatory factor 8 (IRF-8) (Interferon consensus sequence- binding protein) (ICSBP).

IRF8_HUMAN
θ value	5.19021e-56 (rank : 4)	NC score	0.951533 (rank : 4)
Query Neighborhood Hits	41	Target Neighborhood Hits	25	Shared Neighborhood Hits	18
SwissProt Accessions	Q02556	Gene names	IRF8, ICSBP1
Domain Architecture
Description	Interferon regulatory factor 8 (IRF-8) (Interferon consensus sequence- binding protein) (ICSBP).

IRF4_MOUSE
θ value	9.78833e-55 (rank : 5)	NC score	0.944459 (rank : 5)
Query Neighborhood Hits	41	Target Neighborhood Hits	27	Shared Neighborhood Hits	19
SwissProt Accessions	Q64287, Q60802	Gene names	Irf4, Spip
Domain Architecture
Description	Interferon regulatory factor 4 (IRF-4) (Lymphocyte-specific interferon regulatory factor) (LSIRF) (NF-EM5) (PU.1 interaction partner) (Transcriptional activator PIP).

IRF4_HUMAN
θ value	1.84601e-53 (rank : 6)	NC score	0.941721 (rank : 6)
Query Neighborhood Hits	41	Target Neighborhood Hits	31	Shared Neighborhood Hits	18
SwissProt Accessions	Q15306, Q99660	Gene names	IRF4, MUM1
Domain Architecture
Description	Interferon regulatory factor 4 (IRF-4) (Lymphocyte-specific interferon regulatory factor) (LSIRF) (NF-EM5) (Multiple myeloma oncogene 1).

IRF6_HUMAN
θ value	9.83387e-39 (rank : 7)	NC score	0.907542 (rank : 7)
Query Neighborhood Hits	41	Target Neighborhood Hits	30	Shared Neighborhood Hits	18
SwissProt Accessions	O14896	Gene names	IRF6
Domain Architecture
Description	Interferon regulatory factor 6 (IRF-6).

IRF6_MOUSE
θ value	2.19075e-38 (rank : 8)	NC score	0.907280 (rank : 8)
Query Neighborhood Hits	41	Target Neighborhood Hits	26	Shared Neighborhood Hits	18
SwissProt Accessions	P97431	Gene names	Irf6
Domain Architecture
Description	Interferon regulatory factor 6 (IRF-6).

IRF5_HUMAN
θ value	1.6247e-33 (rank : 9)	NC score	0.892118 (rank : 9)
Query Neighborhood Hits	41	Target Neighborhood Hits	41	Shared Neighborhood Hits	18
SwissProt Accessions	Q13568, Q9BQF0	Gene names	IRF5
Domain Architecture
Description	Interferon regulatory factor 5 (IRF-5).

IRF5_MOUSE
θ value	2.12192e-33 (rank : 10)	NC score	0.891904 (rank : 10)
Query Neighborhood Hits	41	Target Neighborhood Hits	49	Shared Neighborhood Hits	18
SwissProt Accessions	P56477	Gene names	Irf5
Domain Architecture
Description	Interferon regulatory factor 5 (IRF-5).

IRF7_MOUSE
θ value	4.01107e-24 (rank : 11)	NC score	0.851830 (rank : 11)
Query Neighborhood Hits	41	Target Neighborhood Hits	34	Shared Neighborhood Hits	18
SwissProt Accessions	P70434	Gene names	Irf7
Domain Architecture
Description	Interferon regulatory factor 7 (IRF-7).

IRF3_HUMAN
θ value	1.42661e-21 (rank : 12)	NC score	0.837651 (rank : 15)
Query Neighborhood Hits	41	Target Neighborhood Hits	129	Shared Neighborhood Hits	19
SwissProt Accessions	Q14653	Gene names	IRF3
Domain Architecture
Description	Interferon regulatory factor 3 (IRF-3).

IRF1_HUMAN
θ value	3.17815e-21 (rank : 13)	NC score	0.846080 (rank : 13)
Query Neighborhood Hits	41	Target Neighborhood Hits	26	Shared Neighborhood Hits	18
SwissProt Accessions	P10914, Q96GG7	Gene names	IRF1
Domain Architecture
Description	Interferon regulatory factor 1 (IRF-1).

IRF3_MOUSE
θ value	3.17815e-21 (rank : 14)	NC score	0.849513 (rank : 12)
Query Neighborhood Hits	41	Target Neighborhood Hits	25	Shared Neighborhood Hits	18
SwissProt Accessions	P70671	Gene names	Irf3
Domain Architecture
Description	Interferon regulatory factor 3 (IRF-3).

IRF1_MOUSE
θ value	9.24701e-21 (rank : 15)	NC score	0.841748 (rank : 14)
Query Neighborhood Hits	41	Target Neighborhood Hits	27	Shared Neighborhood Hits	18
SwissProt Accessions	P15314	Gene names	Irf1
Domain Architecture
Description	Interferon regulatory factor 1 (IRF-1).

IRF2_HUMAN
θ value	1.02238e-19 (rank : 16)	NC score	0.835783 (rank : 16)
Query Neighborhood Hits	41	Target Neighborhood Hits	35	Shared Neighborhood Hits	18
SwissProt Accessions	P14316, Q96B99	Gene names	IRF2
Domain Architecture
Description	Interferon regulatory factor 2 (IRF-2).

IRF2_MOUSE
θ value	3.88503e-19 (rank : 17)	NC score	0.833152 (rank : 17)
Query Neighborhood Hits	41	Target Neighborhood Hits	49	Shared Neighborhood Hits	19
SwissProt Accessions	P23906	Gene names	Irf2
Domain Architecture
Description	Interferon regulatory factor 2 (IRF-2).

IRF7_HUMAN
θ value	3.28887e-18 (rank : 18)	NC score	0.822407 (rank : 18)
Query Neighborhood Hits	41	Target Neighborhood Hits	73	Shared Neighborhood Hits	18
SwissProt Accessions	Q92985, O00331, O00332, O00333, O75924	Gene names	IRF7
Domain Architecture
Description	Interferon regulatory factor 7 (IRF-7).

ARI5B_MOUSE
θ value	0.21417 (rank : 19)	NC score	0.032439 (rank : 19)
Query Neighborhood Hits	41	Target Neighborhood Hits	158	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BM75, Q8C0E0, Q8K4G8, Q8K4L9, Q9CU78, Q9JIX4	Gene names	Arid5b, Desrt, Mrf2
Domain Architecture
Description	AT-rich interactive domain-containing protein 5B (ARID domain- containing protein 5B) (MRF1-like) (Modulator recognition factor protein 2) (MRF-2) (Developmentally and sexually retarded with transient immune abnormalities protein).

GTSE1_MOUSE
θ value	0.813845 (rank : 20)	NC score	0.028061 (rank : 20)
Query Neighborhood Hits	41	Target Neighborhood Hits	245	Shared Neighborhood Hits	6
SwissProt Accessions	Q8R080, O89015, Q9CSG9	Gene names	Gtse1, B99
Domain Architecture	No domain graphic available
Description	G2 and S phase expressed protein 1 (Gtse-1) (B99 protein).

X3CL1_MOUSE
θ value	0.813845 (rank : 21)	NC score	0.027118 (rank : 21)
Query Neighborhood Hits	41	Target Neighborhood Hits	90	Shared Neighborhood Hits	2
SwissProt Accessions	O35188, O35933	Gene names	Cx3cl1, Cx3c, Fkn, Scyd1
Domain Architecture
Description	Fractalkine precursor (CX3CL1) (Neurotactin) (CX3C membrane-anchored chemokine) (Small inducible cytokine D1).

PTN23_MOUSE
θ value	1.06291 (rank : 22)	NC score	0.012123 (rank : 27)
Query Neighborhood Hits	41	Target Neighborhood Hits	726	Shared Neighborhood Hits	9
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

CAC1A_HUMAN
θ value	1.81305 (rank : 23)	NC score	0.007351 (rank : 33)
Query Neighborhood Hits	41	Target Neighborhood Hits	387	Shared Neighborhood Hits	5
SwissProt Accessions	O00555, P78510, P78511, Q16290, Q92690, Q99790, Q99791, Q99792, Q99793	Gene names	CACNA1A, CACH4, CACN3, CACNL1A4
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

RPC5_MOUSE
θ value	1.81305 (rank : 24)	NC score	0.021874 (rank : 22)
Query Neighborhood Hits	41	Target Neighborhood Hits	40	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CZT4, Q8CI35, Q9DBD1	Gene names	Polr3e, Sin
Domain Architecture
Description	DNA-directed RNA polymerases III 80 kDa polypeptide (EC 2.7.7.6) (RNA polymerase III subunit 5) (RPC5) (Sex-lethal interactor homolog).

CSPG3_HUMAN
θ value	2.36792 (rank : 25)	NC score	0.004577 (rank : 35)
Query Neighborhood Hits	41	Target Neighborhood Hits	676	Shared Neighborhood Hits	5
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

SOX13_MOUSE
θ value	2.36792 (rank : 26)	NC score	0.009285 (rank : 30)
Query Neighborhood Hits	41	Target Neighborhood Hits	495	Shared Neighborhood Hits	7
SwissProt Accessions	Q04891, Q922L3	Gene names	Sox13, Sox-13
Domain Architecture
Description	SOX-13 protein.

BAT2_MOUSE
θ value	3.0926 (rank : 27)	NC score	0.012115 (rank : 28)
Query Neighborhood Hits	41	Target Neighborhood Hits	947	Shared Neighborhood Hits	11
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

ANR11_HUMAN
θ value	4.03905 (rank : 28)	NC score	0.003336 (rank : 36)
Query Neighborhood Hits	41	Target Neighborhood Hits	1289	Shared Neighborhood Hits	8
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

SYMM_MOUSE
θ value	5.27518 (rank : 29)	NC score	0.016971 (rank : 23)
Query Neighborhood Hits	41	Target Neighborhood Hits	28	Shared Neighborhood Hits	3
SwissProt Accessions	Q499X9, Q3T9W7, Q8BWR9, Q8BXY1	Gene names	Mars2
Domain Architecture	No domain graphic available
Description	Methionyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.10) (Methionine--tRNA ligase 2) (Mitochondrial methionine--tRNA ligase) (MtMetRS).

UBP2L_HUMAN
θ value	5.27518 (rank : 30)	NC score	0.013739 (rank : 25)
Query Neighborhood Hits	41	Target Neighborhood Hits	170	Shared Neighborhood Hits	4
SwissProt Accessions	Q14157, Q5VU75, Q5VU76, Q9BTU3, Q9UGL5	Gene names	UBAP2L, KIAA0144, NICE4
Domain Architecture
Description	Ubiquitin-associated protein 2-like (Protein NICE-4).

WEE1B_HUMAN
θ value	5.27518 (rank : 31)	NC score	0.000650 (rank : 40)
Query Neighborhood Hits	41	Target Neighborhood Hits	836	Shared Neighborhood Hits	4
SwissProt Accessions	P0C1S8	Gene names	WEE1B, WEE2
Domain Architecture	No domain graphic available
Description	Wee1-like protein kinase 1B (EC 2.7.10.2) (Wee1B kinase).

PAFA2_HUMAN
θ value	6.88961 (rank : 32)	NC score	0.015577 (rank : 24)
Query Neighborhood Hits	41	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	Q99487, O15458	Gene names	PAFAH2
Domain Architecture
Description	Platelet-activating factor acetylhydrolase 2, cytoplasmic (EC 3.1.1.47) (Serine-dependent phospholipase A2) (HSD-PLA2).

RAPH1_HUMAN
θ value	6.88961 (rank : 33)	NC score	0.012686 (rank : 26)
Query Neighborhood Hits	41	Target Neighborhood Hits	593	Shared Neighborhood Hits	10
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

TENS4_HUMAN
θ value	6.88961 (rank : 34)	NC score	0.010061 (rank : 29)
Query Neighborhood Hits	41	Target Neighborhood Hits	214	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IZW8, Q71RB7, Q8WV64, Q96JV4	Gene names	TNS4, CTEN
Domain Architecture	No domain graphic available
Description	Tensin-4 precursor (C-terminal tensin-like protein).

MLL2_HUMAN
θ value	8.99809 (rank : 35)	NC score	0.002095 (rank : 39)
Query Neighborhood Hits	41	Target Neighborhood Hits	1788	Shared Neighborhood Hits	12
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

NALP5_MOUSE
θ value	8.99809 (rank : 36)	NC score	0.002538 (rank : 38)
Query Neighborhood Hits	41	Target Neighborhood Hits	560	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

NBEA_HUMAN
θ value	8.99809 (rank : 37)	NC score	0.008064 (rank : 31)
Query Neighborhood Hits	41	Target Neighborhood Hits	186	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NFP9, Q9HCM8, Q9NSU1, Q9NW98, Q9Y6J1	Gene names	NBEA, BCL8B, KIAA1544, LYST2
Domain Architecture
Description	Protein neurobeachin (Lysosomal-trafficking regulator 2) (Protein BCL8B).

NBEA_MOUSE
θ value	8.99809 (rank : 38)	NC score	0.007964 (rank : 32)
Query Neighborhood Hits	41	Target Neighborhood Hits	225	Shared Neighborhood Hits	5
SwissProt Accessions	Q9EPN1, Q8C931, Q9EPM9, Q9EPN0, Q9WVM9	Gene names	Nbea, Lyst2
Domain Architecture
Description	Protein neurobeachin (Lysosomal-trafficking regulator 2).

TITIN_HUMAN
θ value	8.99809 (rank : 39)	NC score	-0.003510 (rank : 41)
Query Neighborhood Hits	41	Target Neighborhood Hits	2923	Shared Neighborhood Hits	11
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

WDR33_HUMAN
θ value	8.99809 (rank : 40)	NC score	0.003114 (rank : 37)
Query Neighborhood Hits	41	Target Neighborhood Hits	638	Shared Neighborhood Hits	9
SwissProt Accessions	Q9C0J8	Gene names	WDR33, WDC146
Domain Architecture
Description	WD repeat protein 33 (WD repeat protein WDC146).

ZF106_MOUSE
θ value	8.99809 (rank : 41)	NC score	0.004631 (rank : 34)
Query Neighborhood Hits	41	Target Neighborhood Hits	472	Shared Neighborhood Hits	8
SwissProt Accessions	O88466, O55185, O88465, O88467, Q792M1, Q792P4, Q8CDZ8, Q8R3I4, Q9ESU3	Gene names	Zfp106, H3a, Sh3bp3, Sirm, Znf474
Domain Architecture	No domain graphic available
Description	Zinc finger protein 106 (Zfp-106) (Zinc finger protein 474) (H3a minor histocompatibility antigen) (Son of insulin receptor mutant).

Hits sorted by NC score

IRTF_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	41	Target Neighborhood Hits	41	Shared Neighborhood Hits	41
SwissProt Accessions	Q00978	Gene names	ISGF3G, IRF9
Domain Architecture
Description	Transcriptional regulator ISGF3 subunit gamma (Interferon regulatory factor 9) (IRF-9) (IFN-alpha-responsive transcription factor subunit) (Interferon-stimulated gene factor 3 gamma) (ISGF3 p48 subunit) (ISGF- 3 gamma).

IRTF_MOUSE
NC score	0.991530 (rank : 2)	θ value	2.85966e-155 (rank : 2)
Query Neighborhood Hits	41	Target Neighborhood Hits	26	Shared Neighborhood Hits	20
SwissProt Accessions	Q61179	Gene names	Isgf3g
Domain Architecture
Description	Transcriptional regulator ISGF3 subunit gamma (IFN-alpha-responsive transcription factor subunit) (Interferon-stimulated gene factor 3 gamma) (ISGF3 p48 subunit) (ISGF-3 gamma).

IRF8_MOUSE
NC score	0.951543 (rank : 3)	θ value	8.55514e-59 (rank : 3)
Query Neighborhood Hits	41	Target Neighborhood Hits	31	Shared Neighborhood Hits	18
SwissProt Accessions	P23611	Gene names	Irf8, Icsbp, Icsbp1
Domain Architecture
Description	Interferon regulatory factor 8 (IRF-8) (Interferon consensus sequence- binding protein) (ICSBP).

IRF8_HUMAN
NC score	0.951533 (rank : 4)	θ value	5.19021e-56 (rank : 4)
Query Neighborhood Hits	41	Target Neighborhood Hits	25	Shared Neighborhood Hits	18
SwissProt Accessions	Q02556	Gene names	IRF8, ICSBP1
Domain Architecture
Description	Interferon regulatory factor 8 (IRF-8) (Interferon consensus sequence- binding protein) (ICSBP).

IRF4_MOUSE
NC score	0.944459 (rank : 5)	θ value	9.78833e-55 (rank : 5)
Query Neighborhood Hits	41	Target Neighborhood Hits	27	Shared Neighborhood Hits	19
SwissProt Accessions	Q64287, Q60802	Gene names	Irf4, Spip
Domain Architecture
Description	Interferon regulatory factor 4 (IRF-4) (Lymphocyte-specific interferon regulatory factor) (LSIRF) (NF-EM5) (PU.1 interaction partner) (Transcriptional activator PIP).

IRF4_HUMAN
NC score	0.941721 (rank : 6)	θ value	1.84601e-53 (rank : 6)
Query Neighborhood Hits	41	Target Neighborhood Hits	31	Shared Neighborhood Hits	18
SwissProt Accessions	Q15306, Q99660	Gene names	IRF4, MUM1
Domain Architecture
Description	Interferon regulatory factor 4 (IRF-4) (Lymphocyte-specific interferon regulatory factor) (LSIRF) (NF-EM5) (Multiple myeloma oncogene 1).

IRF6_HUMAN
NC score	0.907542 (rank : 7)	θ value	9.83387e-39 (rank : 7)
Query Neighborhood Hits	41	Target Neighborhood Hits	30	Shared Neighborhood Hits	18
SwissProt Accessions	O14896	Gene names	IRF6
Domain Architecture
Description	Interferon regulatory factor 6 (IRF-6).

IRF6_MOUSE
NC score	0.907280 (rank : 8)	θ value	2.19075e-38 (rank : 8)
Query Neighborhood Hits	41	Target Neighborhood Hits	26	Shared Neighborhood Hits	18
SwissProt Accessions	P97431	Gene names	Irf6
Domain Architecture
Description	Interferon regulatory factor 6 (IRF-6).

IRF5_HUMAN
NC score	0.892118 (rank : 9)	θ value	1.6247e-33 (rank : 9)
Query Neighborhood Hits	41	Target Neighborhood Hits	41	Shared Neighborhood Hits	18
SwissProt Accessions	Q13568, Q9BQF0	Gene names	IRF5
Domain Architecture
Description	Interferon regulatory factor 5 (IRF-5).

IRF5_MOUSE
NC score	0.891904 (rank : 10)	θ value	2.12192e-33 (rank : 10)
Query Neighborhood Hits	41	Target Neighborhood Hits	49	Shared Neighborhood Hits	18
SwissProt Accessions	P56477	Gene names	Irf5
Domain Architecture
Description	Interferon regulatory factor 5 (IRF-5).

IRF7_MOUSE
NC score	0.851830 (rank : 11)	θ value	4.01107e-24 (rank : 11)
Query Neighborhood Hits	41	Target Neighborhood Hits	34	Shared Neighborhood Hits	18
SwissProt Accessions	P70434	Gene names	Irf7
Domain Architecture
Description	Interferon regulatory factor 7 (IRF-7).

IRF3_MOUSE
NC score	0.849513 (rank : 12)	θ value	3.17815e-21 (rank : 14)
Query Neighborhood Hits	41	Target Neighborhood Hits	25	Shared Neighborhood Hits	18
SwissProt Accessions	P70671	Gene names	Irf3
Domain Architecture
Description	Interferon regulatory factor 3 (IRF-3).

IRF1_HUMAN
NC score	0.846080 (rank : 13)	θ value	3.17815e-21 (rank : 13)
Query Neighborhood Hits	41	Target Neighborhood Hits	26	Shared Neighborhood Hits	18
SwissProt Accessions	P10914, Q96GG7	Gene names	IRF1
Domain Architecture
Description	Interferon regulatory factor 1 (IRF-1).

IRF1_MOUSE
NC score	0.841748 (rank : 14)	θ value	9.24701e-21 (rank : 15)
Query Neighborhood Hits	41	Target Neighborhood Hits	27	Shared Neighborhood Hits	18
SwissProt Accessions	P15314	Gene names	Irf1
Domain Architecture
Description	Interferon regulatory factor 1 (IRF-1).

IRF3_HUMAN
NC score	0.837651 (rank : 15)	θ value	1.42661e-21 (rank : 12)
Query Neighborhood Hits	41	Target Neighborhood Hits	129	Shared Neighborhood Hits	19
SwissProt Accessions	Q14653	Gene names	IRF3
Domain Architecture
Description	Interferon regulatory factor 3 (IRF-3).

IRF2_HUMAN
NC score	0.835783 (rank : 16)	θ value	1.02238e-19 (rank : 16)
Query Neighborhood Hits	41	Target Neighborhood Hits	35	Shared Neighborhood Hits	18
SwissProt Accessions	P14316, Q96B99	Gene names	IRF2
Domain Architecture
Description	Interferon regulatory factor 2 (IRF-2).

IRF2_MOUSE
NC score	0.833152 (rank : 17)	θ value	3.88503e-19 (rank : 17)
Query Neighborhood Hits	41	Target Neighborhood Hits	49	Shared Neighborhood Hits	19
SwissProt Accessions	P23906	Gene names	Irf2
Domain Architecture
Description	Interferon regulatory factor 2 (IRF-2).

IRF7_HUMAN
NC score	0.822407 (rank : 18)	θ value	3.28887e-18 (rank : 18)
Query Neighborhood Hits	41	Target Neighborhood Hits	73	Shared Neighborhood Hits	18
SwissProt Accessions	Q92985, O00331, O00332, O00333, O75924	Gene names	IRF7
Domain Architecture
Description	Interferon regulatory factor 7 (IRF-7).

ARI5B_MOUSE
NC score	0.032439 (rank : 19)	θ value	0.21417 (rank : 19)
Query Neighborhood Hits	41	Target Neighborhood Hits	158	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BM75, Q8C0E0, Q8K4G8, Q8K4L9, Q9CU78, Q9JIX4	Gene names	Arid5b, Desrt, Mrf2
Domain Architecture
Description	AT-rich interactive domain-containing protein 5B (ARID domain- containing protein 5B) (MRF1-like) (Modulator recognition factor protein 2) (MRF-2) (Developmentally and sexually retarded with transient immune abnormalities protein).

GTSE1_MOUSE
NC score	0.028061 (rank : 20)	θ value	0.813845 (rank : 20)
Query Neighborhood Hits	41	Target Neighborhood Hits	245	Shared Neighborhood Hits	6
SwissProt Accessions	Q8R080, O89015, Q9CSG9	Gene names	Gtse1, B99
Domain Architecture	No domain graphic available
Description	G2 and S phase expressed protein 1 (Gtse-1) (B99 protein).

X3CL1_MOUSE
NC score	0.027118 (rank : 21)	θ value	0.813845 (rank : 21)
Query Neighborhood Hits	41	Target Neighborhood Hits	90	Shared Neighborhood Hits	2
SwissProt Accessions	O35188, O35933	Gene names	Cx3cl1, Cx3c, Fkn, Scyd1
Domain Architecture
Description	Fractalkine precursor (CX3CL1) (Neurotactin) (CX3C membrane-anchored chemokine) (Small inducible cytokine D1).

RPC5_MOUSE
NC score	0.021874 (rank : 22)	θ value	1.81305 (rank : 24)
Query Neighborhood Hits	41	Target Neighborhood Hits	40	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CZT4, Q8CI35, Q9DBD1	Gene names	Polr3e, Sin
Domain Architecture
Description	DNA-directed RNA polymerases III 80 kDa polypeptide (EC 2.7.7.6) (RNA polymerase III subunit 5) (RPC5) (Sex-lethal interactor homolog).

SYMM_MOUSE
NC score	0.016971 (rank : 23)	θ value	5.27518 (rank : 29)
Query Neighborhood Hits	41	Target Neighborhood Hits	28	Shared Neighborhood Hits	3
SwissProt Accessions	Q499X9, Q3T9W7, Q8BWR9, Q8BXY1	Gene names	Mars2
Domain Architecture	No domain graphic available
Description	Methionyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.10) (Methionine--tRNA ligase 2) (Mitochondrial methionine--tRNA ligase) (MtMetRS).

PAFA2_HUMAN
NC score	0.015577 (rank : 24)	θ value	6.88961 (rank : 32)
Query Neighborhood Hits	41	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	Q99487, O15458	Gene names	PAFAH2
Domain Architecture
Description	Platelet-activating factor acetylhydrolase 2, cytoplasmic (EC 3.1.1.47) (Serine-dependent phospholipase A2) (HSD-PLA2).

UBP2L_HUMAN
NC score	0.013739 (rank : 25)	θ value	5.27518 (rank : 30)
Query Neighborhood Hits	41	Target Neighborhood Hits	170	Shared Neighborhood Hits	4
SwissProt Accessions	Q14157, Q5VU75, Q5VU76, Q9BTU3, Q9UGL5	Gene names	UBAP2L, KIAA0144, NICE4
Domain Architecture
Description	Ubiquitin-associated protein 2-like (Protein NICE-4).

RAPH1_HUMAN
NC score	0.012686 (rank : 26)	θ value	6.88961 (rank : 33)
Query Neighborhood Hits	41	Target Neighborhood Hits	593	Shared Neighborhood Hits	10
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

PTN23_MOUSE
NC score	0.012123 (rank : 27)	θ value	1.06291 (rank : 22)
Query Neighborhood Hits	41	Target Neighborhood Hits	726	Shared Neighborhood Hits	9
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

BAT2_MOUSE
NC score	0.012115 (rank : 28)	θ value	3.0926 (rank : 27)
Query Neighborhood Hits	41	Target Neighborhood Hits	947	Shared Neighborhood Hits	11
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

TENS4_HUMAN
NC score	0.010061 (rank : 29)	θ value	6.88961 (rank : 34)
Query Neighborhood Hits	41	Target Neighborhood Hits	214	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IZW8, Q71RB7, Q8WV64, Q96JV4	Gene names	TNS4, CTEN
Domain Architecture	No domain graphic available
Description	Tensin-4 precursor (C-terminal tensin-like protein).

SOX13_MOUSE
NC score	0.009285 (rank : 30)	θ value	2.36792 (rank : 26)
Query Neighborhood Hits	41	Target Neighborhood Hits	495	Shared Neighborhood Hits	7
SwissProt Accessions	Q04891, Q922L3	Gene names	Sox13, Sox-13
Domain Architecture
Description	SOX-13 protein.

NBEA_HUMAN
NC score	0.008064 (rank : 31)	θ value	8.99809 (rank : 37)
Query Neighborhood Hits	41	Target Neighborhood Hits	186	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NFP9, Q9HCM8, Q9NSU1, Q9NW98, Q9Y6J1	Gene names	NBEA, BCL8B, KIAA1544, LYST2
Domain Architecture
Description	Protein neurobeachin (Lysosomal-trafficking regulator 2) (Protein BCL8B).

NBEA_MOUSE
NC score	0.007964 (rank : 32)	θ value	8.99809 (rank : 38)
Query Neighborhood Hits	41	Target Neighborhood Hits	225	Shared Neighborhood Hits	5
SwissProt Accessions	Q9EPN1, Q8C931, Q9EPM9, Q9EPN0, Q9WVM9	Gene names	Nbea, Lyst2
Domain Architecture
Description	Protein neurobeachin (Lysosomal-trafficking regulator 2).

CAC1A_HUMAN
NC score	0.007351 (rank : 33)	θ value	1.81305 (rank : 23)
Query Neighborhood Hits	41	Target Neighborhood Hits	387	Shared Neighborhood Hits	5
SwissProt Accessions	O00555, P78510, P78511, Q16290, Q92690, Q99790, Q99791, Q99792, Q99793	Gene names	CACNA1A, CACH4, CACN3, CACNL1A4
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

ZF106_MOUSE
NC score	0.004631 (rank : 34)	θ value	8.99809 (rank : 41)
Query Neighborhood Hits	41	Target Neighborhood Hits	472	Shared Neighborhood Hits	8
SwissProt Accessions	O88466, O55185, O88465, O88467, Q792M1, Q792P4, Q8CDZ8, Q8R3I4, Q9ESU3	Gene names	Zfp106, H3a, Sh3bp3, Sirm, Znf474
Domain Architecture	No domain graphic available
Description	Zinc finger protein 106 (Zfp-106) (Zinc finger protein 474) (H3a minor histocompatibility antigen) (Son of insulin receptor mutant).

CSPG3_HUMAN
NC score	0.004577 (rank : 35)	θ value	2.36792 (rank : 25)
Query Neighborhood Hits	41	Target Neighborhood Hits	676	Shared Neighborhood Hits	5
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

ANR11_HUMAN
NC score	0.003336 (rank : 36)	θ value	4.03905 (rank : 28)
Query Neighborhood Hits	41	Target Neighborhood Hits	1289	Shared Neighborhood Hits	8
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

WDR33_HUMAN
NC score	0.003114 (rank : 37)	θ value	8.99809 (rank : 40)
Query Neighborhood Hits	41	Target Neighborhood Hits	638	Shared Neighborhood Hits	9
SwissProt Accessions	Q9C0J8	Gene names	WDR33, WDC146
Domain Architecture
Description	WD repeat protein 33 (WD repeat protein WDC146).

NALP5_MOUSE
NC score	0.002538 (rank : 38)	θ value	8.99809 (rank : 36)
Query Neighborhood Hits	41	Target Neighborhood Hits	560	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

MLL2_HUMAN
NC score	0.002095 (rank : 39)	θ value	8.99809 (rank : 35)
Query Neighborhood Hits	41	Target Neighborhood Hits	1788	Shared Neighborhood Hits	12
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

WEE1B_HUMAN
NC score	0.000650 (rank : 40)	θ value	5.27518 (rank : 31)
Query Neighborhood Hits	41	Target Neighborhood Hits	836	Shared Neighborhood Hits	4
SwissProt Accessions	P0C1S8	Gene names	WEE1B, WEE2
Domain Architecture	No domain graphic available
Description	Wee1-like protein kinase 1B (EC 2.7.10.2) (Wee1B kinase).

TITIN_HUMAN
NC score	-0.003510 (rank : 41)	θ value	8.99809 (rank : 39)
Query Neighborhood Hits	41	Target Neighborhood Hits	2923	Shared Neighborhood Hits	11
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).