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Network neighborhood for query Sequence : IRF2_MOUSE

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IRF2_MOUSE
SwissProt Accessions	P23906	Gene names	Irf2
Domain Architecture
Description	Interferon regulatory factor 2 (IRF-2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

IRF2_MOUSE
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	49	Target Neighborhood Hits	49	Shared Neighborhood Hits	49
SwissProt Accessions	P23906	Gene names	Irf2
Domain Architecture
Description	Interferon regulatory factor 2 (IRF-2).

IRF2_HUMAN
θ value	9.76035e-180 (rank : 2)	NC score	0.995268 (rank : 2)
Query Neighborhood Hits	49	Target Neighborhood Hits	35	Shared Neighborhood Hits	25
SwissProt Accessions	P14316, Q96B99	Gene names	IRF2
Domain Architecture
Description	Interferon regulatory factor 2 (IRF-2).

IRF1_MOUSE
θ value	2.18062e-54 (rank : 3)	NC score	0.944771 (rank : 3)
Query Neighborhood Hits	49	Target Neighborhood Hits	27	Shared Neighborhood Hits	18
SwissProt Accessions	P15314	Gene names	Irf1
Domain Architecture
Description	Interferon regulatory factor 1 (IRF-1).

IRF1_HUMAN
θ value	5.93839e-52 (rank : 4)	NC score	0.944367 (rank : 4)
Query Neighborhood Hits	49	Target Neighborhood Hits	26	Shared Neighborhood Hits	18
SwissProt Accessions	P10914, Q96GG7	Gene names	IRF1
Domain Architecture
Description	Interferon regulatory factor 1 (IRF-1).

IRF4_HUMAN
θ value	7.80994e-28 (rank : 5)	NC score	0.852593 (rank : 8)
Query Neighborhood Hits	49	Target Neighborhood Hits	31	Shared Neighborhood Hits	19
SwissProt Accessions	Q15306, Q99660	Gene names	IRF4, MUM1
Domain Architecture
Description	Interferon regulatory factor 4 (IRF-4) (Lymphocyte-specific interferon regulatory factor) (LSIRF) (NF-EM5) (Multiple myeloma oncogene 1).

IRF4_MOUSE
θ value	1.33217e-27 (rank : 6)	NC score	0.853846 (rank : 7)
Query Neighborhood Hits	49	Target Neighborhood Hits	27	Shared Neighborhood Hits	19
SwissProt Accessions	Q64287, Q60802	Gene names	Irf4, Spip
Domain Architecture
Description	Interferon regulatory factor 4 (IRF-4) (Lymphocyte-specific interferon regulatory factor) (LSIRF) (NF-EM5) (PU.1 interaction partner) (Transcriptional activator PIP).

IRF8_MOUSE
θ value	6.61148e-27 (rank : 7)	NC score	0.854431 (rank : 6)
Query Neighborhood Hits	49	Target Neighborhood Hits	31	Shared Neighborhood Hits	18
SwissProt Accessions	P23611	Gene names	Irf8, Icsbp, Icsbp1
Domain Architecture
Description	Interferon regulatory factor 8 (IRF-8) (Interferon consensus sequence- binding protein) (ICSBP).

IRF8_HUMAN
θ value	1.12775e-26 (rank : 8)	NC score	0.855631 (rank : 5)
Query Neighborhood Hits	49	Target Neighborhood Hits	25	Shared Neighborhood Hits	18
SwissProt Accessions	Q02556	Gene names	IRF8, ICSBP1
Domain Architecture
Description	Interferon regulatory factor 8 (IRF-8) (Interferon consensus sequence- binding protein) (ICSBP).

IRF5_MOUSE
θ value	1.05554e-24 (rank : 9)	NC score	0.835749 (rank : 10)
Query Neighborhood Hits	49	Target Neighborhood Hits	49	Shared Neighborhood Hits	18
SwissProt Accessions	P56477	Gene names	Irf5
Domain Architecture
Description	Interferon regulatory factor 5 (IRF-5).

IRF5_HUMAN
θ value	1.37858e-24 (rank : 10)	NC score	0.837090 (rank : 9)
Query Neighborhood Hits	49	Target Neighborhood Hits	41	Shared Neighborhood Hits	18
SwissProt Accessions	Q13568, Q9BQF0	Gene names	IRF5
Domain Architecture
Description	Interferon regulatory factor 5 (IRF-5).

IRF6_HUMAN
θ value	5.23862e-24 (rank : 11)	NC score	0.834325 (rank : 12)
Query Neighborhood Hits	49	Target Neighborhood Hits	30	Shared Neighborhood Hits	18
SwissProt Accessions	O14896	Gene names	IRF6
Domain Architecture
Description	Interferon regulatory factor 6 (IRF-6).

IRF6_MOUSE
θ value	5.23862e-24 (rank : 12)	NC score	0.834331 (rank : 11)
Query Neighborhood Hits	49	Target Neighborhood Hits	26	Shared Neighborhood Hits	18
SwissProt Accessions	P97431	Gene names	Irf6
Domain Architecture
Description	Interferon regulatory factor 6 (IRF-6).

IRTF_MOUSE
θ value	1.02238e-19 (rank : 13)	NC score	0.828121 (rank : 14)
Query Neighborhood Hits	49	Target Neighborhood Hits	26	Shared Neighborhood Hits	18
SwissProt Accessions	Q61179	Gene names	Isgf3g
Domain Architecture
Description	Transcriptional regulator ISGF3 subunit gamma (IFN-alpha-responsive transcription factor subunit) (Interferon-stimulated gene factor 3 gamma) (ISGF3 p48 subunit) (ISGF-3 gamma).

IRTF_HUMAN
θ value	3.88503e-19 (rank : 14)	NC score	0.833152 (rank : 13)
Query Neighborhood Hits	49	Target Neighborhood Hits	41	Shared Neighborhood Hits	19
SwissProt Accessions	Q00978	Gene names	ISGF3G, IRF9
Domain Architecture
Description	Transcriptional regulator ISGF3 subunit gamma (Interferon regulatory factor 9) (IRF-9) (IFN-alpha-responsive transcription factor subunit) (Interferon-stimulated gene factor 3 gamma) (ISGF3 p48 subunit) (ISGF- 3 gamma).

IRF3_HUMAN
θ value	4.02038e-16 (rank : 15)	NC score	0.779761 (rank : 16)
Query Neighborhood Hits	49	Target Neighborhood Hits	129	Shared Neighborhood Hits	20
SwissProt Accessions	Q14653	Gene names	IRF3
Domain Architecture
Description	Interferon regulatory factor 3 (IRF-3).

IRF3_MOUSE
θ value	2.20605e-14 (rank : 16)	NC score	0.786874 (rank : 15)
Query Neighborhood Hits	49	Target Neighborhood Hits	25	Shared Neighborhood Hits	18
SwissProt Accessions	P70671	Gene names	Irf3
Domain Architecture
Description	Interferon regulatory factor 3 (IRF-3).

IRF7_MOUSE
θ value	3.18553e-13 (rank : 17)	NC score	0.768967 (rank : 17)
Query Neighborhood Hits	49	Target Neighborhood Hits	34	Shared Neighborhood Hits	18
SwissProt Accessions	P70434	Gene names	Irf7
Domain Architecture
Description	Interferon regulatory factor 7 (IRF-7).

IRF7_HUMAN
θ value	1.47974e-10 (rank : 18)	NC score	0.740086 (rank : 18)
Query Neighborhood Hits	49	Target Neighborhood Hits	73	Shared Neighborhood Hits	18
SwissProt Accessions	Q92985, O00331, O00332, O00333, O75924	Gene names	IRF7
Domain Architecture
Description	Interferon regulatory factor 7 (IRF-7).

KIF1C_HUMAN
θ value	0.000786445 (rank : 19)	NC score	0.045438 (rank : 19)
Query Neighborhood Hits	49	Target Neighborhood Hits	128	Shared Neighborhood Hits	5
SwissProt Accessions	O43896, O75186	Gene names	KIF1C, KIAA0706
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF1C.

KIF1C_MOUSE
θ value	0.00665767 (rank : 20)	NC score	0.040147 (rank : 20)
Query Neighborhood Hits	49	Target Neighborhood Hits	171	Shared Neighborhood Hits	6
SwissProt Accessions	O35071, Q5SX62	Gene names	Kif1c
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF1C.

RAPH1_HUMAN
θ value	0.0113563 (rank : 21)	NC score	0.038238 (rank : 22)
Query Neighborhood Hits	49	Target Neighborhood Hits	593	Shared Neighborhood Hits	6
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

PDE3A_HUMAN
θ value	0.21417 (rank : 22)	NC score	0.023310 (rank : 25)
Query Neighborhood Hits	49	Target Neighborhood Hits	79	Shared Neighborhood Hits	3
SwissProt Accessions	Q14432, O60865, Q13348	Gene names	PDE3A
Domain Architecture
Description	cGMP-inhibited 3',5'-cyclic phosphodiesterase A (EC 3.1.4.17) (Cyclic GMP-inhibited phosphodiesterase A) (CGI-PDE A).

NOLC1_HUMAN
θ value	0.279714 (rank : 23)	NC score	0.029995 (rank : 23)
Query Neighborhood Hits	49	Target Neighborhood Hits	452	Shared Neighborhood Hits	8
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

TACC2_HUMAN
θ value	0.62314 (rank : 24)	NC score	0.014747 (rank : 32)
Query Neighborhood Hits	49	Target Neighborhood Hits	856	Shared Neighborhood Hits	8
SwissProt Accessions	O95359, Q9NZ41, Q9NZR5	Gene names	TACC2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2 (Anti Zuai-1) (AZU-1).

DMXL1_MOUSE
θ value	1.38821 (rank : 25)	NC score	0.015348 (rank : 30)
Query Neighborhood Hits	49	Target Neighborhood Hits	257	Shared Neighborhood Hits	2
SwissProt Accessions	Q6PNC0, Q3TLG8, Q6PHM6, Q8BQF2	Gene names	Dmxl1
Domain Architecture	No domain graphic available
Description	Protein DmX-like 1 (X-like 1 protein).

NEK1_MOUSE
θ value	1.38821 (rank : 26)	NC score	0.001955 (rank : 46)
Query Neighborhood Hits	49	Target Neighborhood Hits	1311	Shared Neighborhood Hits	10
SwissProt Accessions	P51954	Gene names	Nek1
Domain Architecture
Description	Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (NimA-related protein kinase 1).

RHG26_HUMAN
θ value	2.36792 (rank : 27)	NC score	0.009335 (rank : 38)
Query Neighborhood Hits	49	Target Neighborhood Hits	281	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UNA1, O75117, Q9BYS6, Q9BYS7, Q9UJ00	Gene names	ARHGAP26, GRAF, KIAA0621, OPHN1L
Domain Architecture
Description	Rho-GTPase-activating protein 26 (Oligophrenin-1-like protein) (GTPase regulator associated with focal adhesion kinase).

KATL1_MOUSE
θ value	3.0926 (rank : 28)	NC score	0.009853 (rank : 36)
Query Neighborhood Hits	49	Target Neighborhood Hits	77	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K0T4	Gene names	Katnal1
Domain Architecture	No domain graphic available
Description	Katanin p60 ATPase-containing subunit A-like 1 (EC 3.6.4.3) (Katanin p60 subunit A-like 1) (p60 katanin-like 1).

ARI1A_HUMAN
θ value	4.03905 (rank : 29)	NC score	0.009888 (rank : 35)
Query Neighborhood Hits	49	Target Neighborhood Hits	787	Shared Neighborhood Hits	7
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

CT149_MOUSE
θ value	4.03905 (rank : 30)	NC score	0.040097 (rank : 21)
Query Neighborhood Hits	49	Target Neighborhood Hits	6	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CR37	Gene names
Domain Architecture	No domain graphic available
Description	UPF0362 protein C20orf149 homolog.

KATL1_HUMAN
θ value	4.03905 (rank : 31)	NC score	0.009424 (rank : 37)
Query Neighborhood Hits	49	Target Neighborhood Hits	80	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BW62	Gene names	KATNAL1
Domain Architecture	No domain graphic available
Description	Katanin p60 ATPase-containing subunit A-like 1 (EC 3.6.4.3) (Katanin p60 subunit A-like 1) (p60 katanin-like 1).

RIMB1_HUMAN
θ value	4.03905 (rank : 32)	NC score	0.009148 (rank : 39)
Query Neighborhood Hits	49	Target Neighborhood Hits	1479	Shared Neighborhood Hits	10
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

ZN295_HUMAN
θ value	4.03905 (rank : 33)	NC score	0.000638 (rank : 47)
Query Neighborhood Hits	49	Target Neighborhood Hits	847	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ULJ3, Q6P4R0	Gene names	ZNF295, KIAA1227, ZBTB21
Domain Architecture
Description	Zinc finger protein 295 (Zinc finger and BTB domain-containing protein 21).

PSMD5_MOUSE
θ value	5.27518 (rank : 34)	NC score	0.021923 (rank : 26)
Query Neighborhood Hits	49	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BJY1, Q3UFV2, Q8BMA9, Q8VEE9	Gene names	Psmd5
Domain Architecture	No domain graphic available
Description	26S proteasome non-ATPase regulatory subunit 5 (26S proteasome subunit S5B) (26S protease subunit S5 basic).

RIMB1_MOUSE
θ value	5.27518 (rank : 35)	NC score	0.007155 (rank : 41)
Query Neighborhood Hits	49	Target Neighborhood Hits	1376	Shared Neighborhood Hits	12
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

S6OS1_MOUSE
θ value	5.27518 (rank : 36)	NC score	0.014371 (rank : 33)
Query Neighborhood Hits	49	Target Neighborhood Hits	105	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CTN5, Q9D5F5, Q9D5Y9	Gene names	Six6os1
Domain Architecture	No domain graphic available
Description	Protein SIX6OS1 (Six6 opposite strand transcript 1).

ATF5_MOUSE
θ value	6.88961 (rank : 37)	NC score	0.025106 (rank : 24)
Query Neighborhood Hits	49	Target Neighborhood Hits	62	Shared Neighborhood Hits	4
SwissProt Accessions	O70191, Q58E51, Q99NH6	Gene names	Atf5, Atfx, Nap1
Domain Architecture	No domain graphic available
Description	Cyclic AMP-dependent transcription factor ATF-5 (Activating transcription factor 5-alpha/beta) (Transcription factor ATFx) (Transcription factor-like protein ODA-10) (BZIP protein ATF7) (NRIF3- associated protein) (NAP1).

MAP1B_HUMAN
θ value	6.88961 (rank : 38)	NC score	0.007078 (rank : 42)
Query Neighborhood Hits	49	Target Neighborhood Hits	903	Shared Neighborhood Hits	10
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

MUC7_HUMAN
θ value	6.88961 (rank : 39)	NC score	0.005808 (rank : 44)
Query Neighborhood Hits	49	Target Neighborhood Hits	538	Shared Neighborhood Hits	6
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

PSMD5_HUMAN
θ value	6.88961 (rank : 40)	NC score	0.020800 (rank : 27)
Query Neighborhood Hits	49	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q16401, Q15045	Gene names	PSMD5, KIAA0072
Domain Architecture	No domain graphic available
Description	26S proteasome non-ATPase regulatory subunit 5 (26S proteasome subunit S5B) (26S protease subunit S5 basic).

SURF2_HUMAN
θ value	6.88961 (rank : 41)	NC score	0.015191 (rank : 31)
Query Neighborhood Hits	49	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q15527, Q96CD1	Gene names	SURF2
Domain Architecture
Description	Surfeit locus protein 2 (Surf-2).

TAF1C_HUMAN
θ value	6.88961 (rank : 42)	NC score	0.012501 (rank : 34)
Query Neighborhood Hits	49	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	Q15572, Q59F67, Q8N6V3	Gene names	TAF1C
Domain Architecture	No domain graphic available
Description	TATA box-binding protein-associated factor RNA polymerase I subunit C (TATA box-binding protein-associated factor 1C) (TBP-associated factor 1C) (TBP-associated factor RNA polymerase I 110 kDa) (TAFI110).

ZN688_HUMAN
θ value	6.88961 (rank : 43)	NC score	-0.002381 (rank : 49)
Query Neighborhood Hits	49	Target Neighborhood Hits	873	Shared Neighborhood Hits	5
SwissProt Accessions	Q8WV14, O75701, Q8IW91, Q96MN0	Gene names	ZNF688
Domain Architecture	No domain graphic available
Description	Zinc finger protein 688.

ATF5_HUMAN
θ value	8.99809 (rank : 44)	NC score	0.018123 (rank : 28)
Query Neighborhood Hits	49	Target Neighborhood Hits	99	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y2D1, Q9BSA1, Q9UNQ3	Gene names	ATF5, ATFX
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-5 (Activating transcription factor 5) (Transcription factor ATFx).

BPTF_HUMAN
θ value	8.99809 (rank : 45)	NC score	0.003975 (rank : 45)
Query Neighborhood Hits	49	Target Neighborhood Hits	786	Shared Neighborhood Hits	8
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

BSN_HUMAN
θ value	8.99809 (rank : 46)	NC score	0.008413 (rank : 40)
Query Neighborhood Hits	49	Target Neighborhood Hits	1537	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

IRAK1_HUMAN
θ value	8.99809 (rank : 47)	NC score	-0.000441 (rank : 48)
Query Neighborhood Hits	49	Target Neighborhood Hits	820	Shared Neighborhood Hits	4
SwissProt Accessions	P51617, Q7Z5V4, Q96RL2	Gene names	IRAK1, IRAK
Domain Architecture
Description	Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1) (IRAK-1).

MORC2_HUMAN
θ value	8.99809 (rank : 48)	NC score	0.005828 (rank : 43)
Query Neighborhood Hits	49	Target Neighborhood Hits	207	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y6X9, Q9UF28, Q9Y6V2	Gene names	MORC2, KIAA0852, ZCWCC1
Domain Architecture
Description	MORC family CW-type zinc finger protein 2 (Zinc finger CW-type coiled- coil domain protein 1).

SPDEF_MOUSE
θ value	8.99809 (rank : 49)	NC score	0.017704 (rank : 29)
Query Neighborhood Hits	49	Target Neighborhood Hits	56	Shared Neighborhood Hits	5
SwissProt Accessions	Q9WTP3	Gene names	Spdef, Pdef, Pse
Domain Architecture	No domain graphic available
Description	SAM pointed domain-containing Ets transcription factor (Prostate- derived Ets factor) (Prostate epithelium-specific Ets transcription factor) (Prostate-specific Ets).

Hits sorted by NC score

IRF2_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	49	Target Neighborhood Hits	49	Shared Neighborhood Hits	49
SwissProt Accessions	P23906	Gene names	Irf2
Domain Architecture
Description	Interferon regulatory factor 2 (IRF-2).

IRF2_HUMAN
NC score	0.995268 (rank : 2)	θ value	9.76035e-180 (rank : 2)
Query Neighborhood Hits	49	Target Neighborhood Hits	35	Shared Neighborhood Hits	25
SwissProt Accessions	P14316, Q96B99	Gene names	IRF2
Domain Architecture
Description	Interferon regulatory factor 2 (IRF-2).

IRF1_MOUSE
NC score	0.944771 (rank : 3)	θ value	2.18062e-54 (rank : 3)
Query Neighborhood Hits	49	Target Neighborhood Hits	27	Shared Neighborhood Hits	18
SwissProt Accessions	P15314	Gene names	Irf1
Domain Architecture
Description	Interferon regulatory factor 1 (IRF-1).

IRF1_HUMAN
NC score	0.944367 (rank : 4)	θ value	5.93839e-52 (rank : 4)
Query Neighborhood Hits	49	Target Neighborhood Hits	26	Shared Neighborhood Hits	18
SwissProt Accessions	P10914, Q96GG7	Gene names	IRF1
Domain Architecture
Description	Interferon regulatory factor 1 (IRF-1).

IRF8_HUMAN
NC score	0.855631 (rank : 5)	θ value	1.12775e-26 (rank : 8)
Query Neighborhood Hits	49	Target Neighborhood Hits	25	Shared Neighborhood Hits	18
SwissProt Accessions	Q02556	Gene names	IRF8, ICSBP1
Domain Architecture
Description	Interferon regulatory factor 8 (IRF-8) (Interferon consensus sequence- binding protein) (ICSBP).

IRF8_MOUSE
NC score	0.854431 (rank : 6)	θ value	6.61148e-27 (rank : 7)
Query Neighborhood Hits	49	Target Neighborhood Hits	31	Shared Neighborhood Hits	18
SwissProt Accessions	P23611	Gene names	Irf8, Icsbp, Icsbp1
Domain Architecture
Description	Interferon regulatory factor 8 (IRF-8) (Interferon consensus sequence- binding protein) (ICSBP).

IRF4_MOUSE
NC score	0.853846 (rank : 7)	θ value	1.33217e-27 (rank : 6)
Query Neighborhood Hits	49	Target Neighborhood Hits	27	Shared Neighborhood Hits	19
SwissProt Accessions	Q64287, Q60802	Gene names	Irf4, Spip
Domain Architecture
Description	Interferon regulatory factor 4 (IRF-4) (Lymphocyte-specific interferon regulatory factor) (LSIRF) (NF-EM5) (PU.1 interaction partner) (Transcriptional activator PIP).

IRF4_HUMAN
NC score	0.852593 (rank : 8)	θ value	7.80994e-28 (rank : 5)
Query Neighborhood Hits	49	Target Neighborhood Hits	31	Shared Neighborhood Hits	19
SwissProt Accessions	Q15306, Q99660	Gene names	IRF4, MUM1
Domain Architecture
Description	Interferon regulatory factor 4 (IRF-4) (Lymphocyte-specific interferon regulatory factor) (LSIRF) (NF-EM5) (Multiple myeloma oncogene 1).

IRF5_HUMAN
NC score	0.837090 (rank : 9)	θ value	1.37858e-24 (rank : 10)
Query Neighborhood Hits	49	Target Neighborhood Hits	41	Shared Neighborhood Hits	18
SwissProt Accessions	Q13568, Q9BQF0	Gene names	IRF5
Domain Architecture
Description	Interferon regulatory factor 5 (IRF-5).

IRF5_MOUSE
NC score	0.835749 (rank : 10)	θ value	1.05554e-24 (rank : 9)
Query Neighborhood Hits	49	Target Neighborhood Hits	49	Shared Neighborhood Hits	18
SwissProt Accessions	P56477	Gene names	Irf5
Domain Architecture
Description	Interferon regulatory factor 5 (IRF-5).

IRF6_MOUSE
NC score	0.834331 (rank : 11)	θ value	5.23862e-24 (rank : 12)
Query Neighborhood Hits	49	Target Neighborhood Hits	26	Shared Neighborhood Hits	18
SwissProt Accessions	P97431	Gene names	Irf6
Domain Architecture
Description	Interferon regulatory factor 6 (IRF-6).

IRF6_HUMAN
NC score	0.834325 (rank : 12)	θ value	5.23862e-24 (rank : 11)
Query Neighborhood Hits	49	Target Neighborhood Hits	30	Shared Neighborhood Hits	18
SwissProt Accessions	O14896	Gene names	IRF6
Domain Architecture
Description	Interferon regulatory factor 6 (IRF-6).

IRTF_HUMAN
NC score	0.833152 (rank : 13)	θ value	3.88503e-19 (rank : 14)
Query Neighborhood Hits	49	Target Neighborhood Hits	41	Shared Neighborhood Hits	19
SwissProt Accessions	Q00978	Gene names	ISGF3G, IRF9
Domain Architecture
Description	Transcriptional regulator ISGF3 subunit gamma (Interferon regulatory factor 9) (IRF-9) (IFN-alpha-responsive transcription factor subunit) (Interferon-stimulated gene factor 3 gamma) (ISGF3 p48 subunit) (ISGF- 3 gamma).

IRTF_MOUSE
NC score	0.828121 (rank : 14)	θ value	1.02238e-19 (rank : 13)
Query Neighborhood Hits	49	Target Neighborhood Hits	26	Shared Neighborhood Hits	18
SwissProt Accessions	Q61179	Gene names	Isgf3g
Domain Architecture
Description	Transcriptional regulator ISGF3 subunit gamma (IFN-alpha-responsive transcription factor subunit) (Interferon-stimulated gene factor 3 gamma) (ISGF3 p48 subunit) (ISGF-3 gamma).

IRF3_MOUSE
NC score	0.786874 (rank : 15)	θ value	2.20605e-14 (rank : 16)
Query Neighborhood Hits	49	Target Neighborhood Hits	25	Shared Neighborhood Hits	18
SwissProt Accessions	P70671	Gene names	Irf3
Domain Architecture
Description	Interferon regulatory factor 3 (IRF-3).

IRF3_HUMAN
NC score	0.779761 (rank : 16)	θ value	4.02038e-16 (rank : 15)
Query Neighborhood Hits	49	Target Neighborhood Hits	129	Shared Neighborhood Hits	20
SwissProt Accessions	Q14653	Gene names	IRF3
Domain Architecture
Description	Interferon regulatory factor 3 (IRF-3).

IRF7_MOUSE
NC score	0.768967 (rank : 17)	θ value	3.18553e-13 (rank : 17)
Query Neighborhood Hits	49	Target Neighborhood Hits	34	Shared Neighborhood Hits	18
SwissProt Accessions	P70434	Gene names	Irf7
Domain Architecture
Description	Interferon regulatory factor 7 (IRF-7).

IRF7_HUMAN
NC score	0.740086 (rank : 18)	θ value	1.47974e-10 (rank : 18)
Query Neighborhood Hits	49	Target Neighborhood Hits	73	Shared Neighborhood Hits	18
SwissProt Accessions	Q92985, O00331, O00332, O00333, O75924	Gene names	IRF7
Domain Architecture
Description	Interferon regulatory factor 7 (IRF-7).

KIF1C_HUMAN
NC score	0.045438 (rank : 19)	θ value	0.000786445 (rank : 19)
Query Neighborhood Hits	49	Target Neighborhood Hits	128	Shared Neighborhood Hits	5
SwissProt Accessions	O43896, O75186	Gene names	KIF1C, KIAA0706
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF1C.

KIF1C_MOUSE
NC score	0.040147 (rank : 20)	θ value	0.00665767 (rank : 20)
Query Neighborhood Hits	49	Target Neighborhood Hits	171	Shared Neighborhood Hits	6
SwissProt Accessions	O35071, Q5SX62	Gene names	Kif1c
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF1C.

CT149_MOUSE
NC score	0.040097 (rank : 21)	θ value	4.03905 (rank : 30)
Query Neighborhood Hits	49	Target Neighborhood Hits	6	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CR37	Gene names
Domain Architecture	No domain graphic available
Description	UPF0362 protein C20orf149 homolog.

RAPH1_HUMAN
NC score	0.038238 (rank : 22)	θ value	0.0113563 (rank : 21)
Query Neighborhood Hits	49	Target Neighborhood Hits	593	Shared Neighborhood Hits	6
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

NOLC1_HUMAN
NC score	0.029995 (rank : 23)	θ value	0.279714 (rank : 23)
Query Neighborhood Hits	49	Target Neighborhood Hits	452	Shared Neighborhood Hits	8
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

ATF5_MOUSE
NC score	0.025106 (rank : 24)	θ value	6.88961 (rank : 37)
Query Neighborhood Hits	49	Target Neighborhood Hits	62	Shared Neighborhood Hits	4
SwissProt Accessions	O70191, Q58E51, Q99NH6	Gene names	Atf5, Atfx, Nap1
Domain Architecture	No domain graphic available
Description	Cyclic AMP-dependent transcription factor ATF-5 (Activating transcription factor 5-alpha/beta) (Transcription factor ATFx) (Transcription factor-like protein ODA-10) (BZIP protein ATF7) (NRIF3- associated protein) (NAP1).

PDE3A_HUMAN
NC score	0.023310 (rank : 25)	θ value	0.21417 (rank : 22)
Query Neighborhood Hits	49	Target Neighborhood Hits	79	Shared Neighborhood Hits	3
SwissProt Accessions	Q14432, O60865, Q13348	Gene names	PDE3A
Domain Architecture
Description	cGMP-inhibited 3',5'-cyclic phosphodiesterase A (EC 3.1.4.17) (Cyclic GMP-inhibited phosphodiesterase A) (CGI-PDE A).

PSMD5_MOUSE
NC score	0.021923 (rank : 26)	θ value	5.27518 (rank : 34)
Query Neighborhood Hits	49	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BJY1, Q3UFV2, Q8BMA9, Q8VEE9	Gene names	Psmd5
Domain Architecture	No domain graphic available
Description	26S proteasome non-ATPase regulatory subunit 5 (26S proteasome subunit S5B) (26S protease subunit S5 basic).

PSMD5_HUMAN
NC score	0.020800 (rank : 27)	θ value	6.88961 (rank : 40)
Query Neighborhood Hits	49	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q16401, Q15045	Gene names	PSMD5, KIAA0072
Domain Architecture	No domain graphic available
Description	26S proteasome non-ATPase regulatory subunit 5 (26S proteasome subunit S5B) (26S protease subunit S5 basic).

ATF5_HUMAN
NC score	0.018123 (rank : 28)	θ value	8.99809 (rank : 44)
Query Neighborhood Hits	49	Target Neighborhood Hits	99	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y2D1, Q9BSA1, Q9UNQ3	Gene names	ATF5, ATFX
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-5 (Activating transcription factor 5) (Transcription factor ATFx).

SPDEF_MOUSE
NC score	0.017704 (rank : 29)	θ value	8.99809 (rank : 49)
Query Neighborhood Hits	49	Target Neighborhood Hits	56	Shared Neighborhood Hits	5
SwissProt Accessions	Q9WTP3	Gene names	Spdef, Pdef, Pse
Domain Architecture	No domain graphic available
Description	SAM pointed domain-containing Ets transcription factor (Prostate- derived Ets factor) (Prostate epithelium-specific Ets transcription factor) (Prostate-specific Ets).

DMXL1_MOUSE
NC score	0.015348 (rank : 30)	θ value	1.38821 (rank : 25)
Query Neighborhood Hits	49	Target Neighborhood Hits	257	Shared Neighborhood Hits	2
SwissProt Accessions	Q6PNC0, Q3TLG8, Q6PHM6, Q8BQF2	Gene names	Dmxl1
Domain Architecture	No domain graphic available
Description	Protein DmX-like 1 (X-like 1 protein).

SURF2_HUMAN
NC score	0.015191 (rank : 31)	θ value	6.88961 (rank : 41)
Query Neighborhood Hits	49	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q15527, Q96CD1	Gene names	SURF2
Domain Architecture
Description	Surfeit locus protein 2 (Surf-2).

TACC2_HUMAN
NC score	0.014747 (rank : 32)	θ value	0.62314 (rank : 24)
Query Neighborhood Hits	49	Target Neighborhood Hits	856	Shared Neighborhood Hits	8
SwissProt Accessions	O95359, Q9NZ41, Q9NZR5	Gene names	TACC2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2 (Anti Zuai-1) (AZU-1).

S6OS1_MOUSE
NC score	0.014371 (rank : 33)	θ value	5.27518 (rank : 36)
Query Neighborhood Hits	49	Target Neighborhood Hits	105	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CTN5, Q9D5F5, Q9D5Y9	Gene names	Six6os1
Domain Architecture	No domain graphic available
Description	Protein SIX6OS1 (Six6 opposite strand transcript 1).

TAF1C_HUMAN
NC score	0.012501 (rank : 34)	θ value	6.88961 (rank : 42)
Query Neighborhood Hits	49	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	Q15572, Q59F67, Q8N6V3	Gene names	TAF1C
Domain Architecture	No domain graphic available
Description	TATA box-binding protein-associated factor RNA polymerase I subunit C (TATA box-binding protein-associated factor 1C) (TBP-associated factor 1C) (TBP-associated factor RNA polymerase I 110 kDa) (TAFI110).

ARI1A_HUMAN
NC score	0.009888 (rank : 35)	θ value	4.03905 (rank : 29)
Query Neighborhood Hits	49	Target Neighborhood Hits	787	Shared Neighborhood Hits	7
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

KATL1_MOUSE
NC score	0.009853 (rank : 36)	θ value	3.0926 (rank : 28)
Query Neighborhood Hits	49	Target Neighborhood Hits	77	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K0T4	Gene names	Katnal1
Domain Architecture	No domain graphic available
Description	Katanin p60 ATPase-containing subunit A-like 1 (EC 3.6.4.3) (Katanin p60 subunit A-like 1) (p60 katanin-like 1).

KATL1_HUMAN
NC score	0.009424 (rank : 37)	θ value	4.03905 (rank : 31)
Query Neighborhood Hits	49	Target Neighborhood Hits	80	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BW62	Gene names	KATNAL1
Domain Architecture	No domain graphic available
Description	Katanin p60 ATPase-containing subunit A-like 1 (EC 3.6.4.3) (Katanin p60 subunit A-like 1) (p60 katanin-like 1).

RHG26_HUMAN
NC score	0.009335 (rank : 38)	θ value	2.36792 (rank : 27)
Query Neighborhood Hits	49	Target Neighborhood Hits	281	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UNA1, O75117, Q9BYS6, Q9BYS7, Q9UJ00	Gene names	ARHGAP26, GRAF, KIAA0621, OPHN1L
Domain Architecture
Description	Rho-GTPase-activating protein 26 (Oligophrenin-1-like protein) (GTPase regulator associated with focal adhesion kinase).

RIMB1_HUMAN
NC score	0.009148 (rank : 39)	θ value	4.03905 (rank : 32)
Query Neighborhood Hits	49	Target Neighborhood Hits	1479	Shared Neighborhood Hits	10
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

BSN_HUMAN
NC score	0.008413 (rank : 40)	θ value	8.99809 (rank : 46)
Query Neighborhood Hits	49	Target Neighborhood Hits	1537	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

RIMB1_MOUSE
NC score	0.007155 (rank : 41)	θ value	5.27518 (rank : 35)
Query Neighborhood Hits	49	Target Neighborhood Hits	1376	Shared Neighborhood Hits	12
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

MAP1B_HUMAN
NC score	0.007078 (rank : 42)	θ value	6.88961 (rank : 38)
Query Neighborhood Hits	49	Target Neighborhood Hits	903	Shared Neighborhood Hits	10
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

MORC2_HUMAN
NC score	0.005828 (rank : 43)	θ value	8.99809 (rank : 48)
Query Neighborhood Hits	49	Target Neighborhood Hits	207	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y6X9, Q9UF28, Q9Y6V2	Gene names	MORC2, KIAA0852, ZCWCC1
Domain Architecture
Description	MORC family CW-type zinc finger protein 2 (Zinc finger CW-type coiled- coil domain protein 1).

MUC7_HUMAN
NC score	0.005808 (rank : 44)	θ value	6.88961 (rank : 39)
Query Neighborhood Hits	49	Target Neighborhood Hits	538	Shared Neighborhood Hits	6
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

BPTF_HUMAN
NC score	0.003975 (rank : 45)	θ value	8.99809 (rank : 45)
Query Neighborhood Hits	49	Target Neighborhood Hits	786	Shared Neighborhood Hits	8
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

NEK1_MOUSE
NC score	0.001955 (rank : 46)	θ value	1.38821 (rank : 26)
Query Neighborhood Hits	49	Target Neighborhood Hits	1311	Shared Neighborhood Hits	10
SwissProt Accessions	P51954	Gene names	Nek1
Domain Architecture
Description	Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (NimA-related protein kinase 1).

ZN295_HUMAN
NC score	0.000638 (rank : 47)	θ value	4.03905 (rank : 33)
Query Neighborhood Hits	49	Target Neighborhood Hits	847	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ULJ3, Q6P4R0	Gene names	ZNF295, KIAA1227, ZBTB21
Domain Architecture
Description	Zinc finger protein 295 (Zinc finger and BTB domain-containing protein 21).

IRAK1_HUMAN
NC score	-0.000441 (rank : 48)	θ value	8.99809 (rank : 47)
Query Neighborhood Hits	49	Target Neighborhood Hits	820	Shared Neighborhood Hits	4
SwissProt Accessions	P51617, Q7Z5V4, Q96RL2	Gene names	IRAK1, IRAK
Domain Architecture
Description	Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1) (IRAK-1).

ZN688_HUMAN
NC score	-0.002381 (rank : 49)	θ value	6.88961 (rank : 43)
Query Neighborhood Hits	49	Target Neighborhood Hits	873	Shared Neighborhood Hits	5
SwissProt Accessions	Q8WV14, O75701, Q8IW91, Q96MN0	Gene names	ZNF688
Domain Architecture	No domain graphic available
Description	Zinc finger protein 688.