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Network neighborhood for query Sequence : IRF8_HUMAN

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IRF8_HUMAN
SwissProt Accessions	Q02556	Gene names	IRF8, ICSBP1
Domain Architecture
Description	Interferon regulatory factor 8 (IRF-8) (Interferon consensus sequence- binding protein) (ICSBP).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

IRF8_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	25	Target Neighborhood Hits	25	Shared Neighborhood Hits	25
SwissProt Accessions	Q02556	Gene names	IRF8, ICSBP1
Domain Architecture
Description	Interferon regulatory factor 8 (IRF-8) (Interferon consensus sequence- binding protein) (ICSBP).

IRF8_MOUSE
θ value	0 (rank : 2)	NC score	0.998158 (rank : 2)
Query Neighborhood Hits	25	Target Neighborhood Hits	31	Shared Neighborhood Hits	21
SwissProt Accessions	P23611	Gene names	Irf8, Icsbp, Icsbp1
Domain Architecture
Description	Interferon regulatory factor 8 (IRF-8) (Interferon consensus sequence- binding protein) (ICSBP).

IRF4_MOUSE
θ value	4.21644e-82 (rank : 3)	NC score	0.967237 (rank : 3)
Query Neighborhood Hits	25	Target Neighborhood Hits	27	Shared Neighborhood Hits	18
SwissProt Accessions	Q64287, Q60802	Gene names	Irf4, Spip
Domain Architecture
Description	Interferon regulatory factor 4 (IRF-4) (Lymphocyte-specific interferon regulatory factor) (LSIRF) (NF-EM5) (PU.1 interaction partner) (Transcriptional activator PIP).

IRF4_HUMAN
θ value	5.50685e-82 (rank : 4)	NC score	0.965254 (rank : 4)
Query Neighborhood Hits	25	Target Neighborhood Hits	31	Shared Neighborhood Hits	18
SwissProt Accessions	Q15306, Q99660	Gene names	IRF4, MUM1
Domain Architecture
Description	Interferon regulatory factor 4 (IRF-4) (Lymphocyte-specific interferon regulatory factor) (LSIRF) (NF-EM5) (Multiple myeloma oncogene 1).

IRTF_MOUSE
θ value	2.94036e-59 (rank : 5)	NC score	0.947928 (rank : 6)
Query Neighborhood Hits	25	Target Neighborhood Hits	26	Shared Neighborhood Hits	18
SwissProt Accessions	Q61179	Gene names	Isgf3g
Domain Architecture
Description	Transcriptional regulator ISGF3 subunit gamma (IFN-alpha-responsive transcription factor subunit) (Interferon-stimulated gene factor 3 gamma) (ISGF3 p48 subunit) (ISGF-3 gamma).

IRTF_HUMAN
θ value	5.19021e-56 (rank : 6)	NC score	0.951533 (rank : 5)
Query Neighborhood Hits	25	Target Neighborhood Hits	41	Shared Neighborhood Hits	18
SwissProt Accessions	Q00978	Gene names	ISGF3G, IRF9
Domain Architecture
Description	Transcriptional regulator ISGF3 subunit gamma (Interferon regulatory factor 9) (IRF-9) (IFN-alpha-responsive transcription factor subunit) (Interferon-stimulated gene factor 3 gamma) (ISGF3 p48 subunit) (ISGF- 3 gamma).

IRF5_MOUSE
θ value	3.71957e-54 (rank : 7)	NC score	0.926846 (rank : 9)
Query Neighborhood Hits	25	Target Neighborhood Hits	49	Shared Neighborhood Hits	18
SwissProt Accessions	P56477	Gene names	Irf5
Domain Architecture
Description	Interferon regulatory factor 5 (IRF-5).

IRF6_HUMAN
θ value	5.37103e-53 (rank : 8)	NC score	0.930665 (rank : 8)
Query Neighborhood Hits	25	Target Neighborhood Hits	30	Shared Neighborhood Hits	18
SwissProt Accessions	O14896	Gene names	IRF6
Domain Architecture
Description	Interferon regulatory factor 6 (IRF-6).

IRF6_MOUSE
θ value	5.37103e-53 (rank : 9)	NC score	0.930699 (rank : 7)
Query Neighborhood Hits	25	Target Neighborhood Hits	26	Shared Neighborhood Hits	18
SwissProt Accessions	P97431	Gene names	Irf6
Domain Architecture
Description	Interferon regulatory factor 6 (IRF-6).

IRF5_HUMAN
θ value	5.55816e-50 (rank : 10)	NC score	0.925403 (rank : 10)
Query Neighborhood Hits	25	Target Neighborhood Hits	41	Shared Neighborhood Hits	18
SwissProt Accessions	Q13568, Q9BQF0	Gene names	IRF5
Domain Architecture
Description	Interferon regulatory factor 5 (IRF-5).

IRF3_HUMAN
θ value	1.08979e-29 (rank : 11)	NC score	0.860701 (rank : 14)
Query Neighborhood Hits	25	Target Neighborhood Hits	129	Shared Neighborhood Hits	18
SwissProt Accessions	Q14653	Gene names	IRF3
Domain Architecture
Description	Interferon regulatory factor 3 (IRF-3).

IRF2_MOUSE
θ value	1.12775e-26 (rank : 12)	NC score	0.855631 (rank : 17)
Query Neighborhood Hits	25	Target Neighborhood Hits	49	Shared Neighborhood Hits	18
SwissProt Accessions	P23906	Gene names	Irf2
Domain Architecture
Description	Interferon regulatory factor 2 (IRF-2).

IRF7_MOUSE
θ value	1.47289e-26 (rank : 13)	NC score	0.862165 (rank : 13)
Query Neighborhood Hits	25	Target Neighborhood Hits	34	Shared Neighborhood Hits	18
SwissProt Accessions	P70434	Gene names	Irf7
Domain Architecture
Description	Interferon regulatory factor 7 (IRF-7).

IRF1_HUMAN
θ value	1.92365e-26 (rank : 14)	NC score	0.864427 (rank : 12)
Query Neighborhood Hits	25	Target Neighborhood Hits	26	Shared Neighborhood Hits	18
SwissProt Accessions	P10914, Q96GG7	Gene names	IRF1
Domain Architecture
Description	Interferon regulatory factor 1 (IRF-1).

IRF2_HUMAN
θ value	2.51237e-26 (rank : 15)	NC score	0.857920 (rank : 16)
Query Neighborhood Hits	25	Target Neighborhood Hits	35	Shared Neighborhood Hits	18
SwissProt Accessions	P14316, Q96B99	Gene names	IRF2
Domain Architecture
Description	Interferon regulatory factor 2 (IRF-2).

IRF3_MOUSE
θ value	7.30988e-26 (rank : 16)	NC score	0.868473 (rank : 11)
Query Neighborhood Hits	25	Target Neighborhood Hits	25	Shared Neighborhood Hits	18
SwissProt Accessions	P70671	Gene names	Irf3
Domain Architecture
Description	Interferon regulatory factor 3 (IRF-3).

IRF1_MOUSE
θ value	1.24688e-25 (rank : 17)	NC score	0.859782 (rank : 15)
Query Neighborhood Hits	25	Target Neighborhood Hits	27	Shared Neighborhood Hits	18
SwissProt Accessions	P15314	Gene names	Irf1
Domain Architecture
Description	Interferon regulatory factor 1 (IRF-1).

IRF7_HUMAN
θ value	1.24977e-17 (rank : 18)	NC score	0.827928 (rank : 18)
Query Neighborhood Hits	25	Target Neighborhood Hits	73	Shared Neighborhood Hits	18
SwissProt Accessions	Q92985, O00331, O00332, O00333, O75924	Gene names	IRF7
Domain Architecture
Description	Interferon regulatory factor 7 (IRF-7).

IPF1_MOUSE
θ value	1.06291 (rank : 19)	NC score	0.009204 (rank : 22)
Query Neighborhood Hits	25	Target Neighborhood Hits	340	Shared Neighborhood Hits	3
SwissProt Accessions	P52946	Gene names	Ipf1, Pdx1
Domain Architecture
Description	Insulin promoter factor 1 (IPF-1) (Islet/duodenum homeobox 1) (IDX-1) (Somatostatin-transactivating factor 1) (STF-1) (Pancreas/duodenum homeobox 1).

ANK3_HUMAN
θ value	2.36792 (rank : 20)	NC score	0.002825 (rank : 25)
Query Neighborhood Hits	25	Target Neighborhood Hits	853	Shared Neighborhood Hits	2
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

FA62A_HUMAN
θ value	3.0926 (rank : 21)	NC score	0.014256 (rank : 19)
Query Neighborhood Hits	25	Target Neighborhood Hits	168	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BSJ8, O94848, Q6PJN4, Q9H6J1, Q9H6W2, Q9Y416	Gene names	FAM62A, KIAA0747, MBC2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

PCDA5_HUMAN
θ value	4.03905 (rank : 22)	NC score	0.004369 (rank : 24)
Query Neighborhood Hits	25	Target Neighborhood Hits	217	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y5H7, O75284, Q8N4R3	Gene names	PCDHA5
Domain Architecture
Description	Protocadherin alpha 5 precursor (PCDH-alpha5).

TAI12_MOUSE
θ value	5.27518 (rank : 23)	NC score	0.009277 (rank : 21)
Query Neighborhood Hits	25	Target Neighborhood Hits	34	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BGQ2, Q3UIH1	Gene names	Taip12
Domain Architecture	No domain graphic available
Description	TGF-beta-induced apoptosis protein 12 (TAIP-12).

FBSH_HUMAN
θ value	6.88961 (rank : 24)	NC score	0.011055 (rank : 20)
Query Neighborhood Hits	25	Target Neighborhood Hits	46	Shared Neighborhood Hits	2
SwissProt Accessions	Q9HAH7, Q96CI9, Q9H9X4	Gene names	FBS1, FBS
Domain Architecture	No domain graphic available
Description	Probable fibrosin-1 long transcript protein.

FMN1A_MOUSE
θ value	6.88961 (rank : 25)	NC score	0.005332 (rank : 23)
Query Neighborhood Hits	25	Target Neighborhood Hits	423	Shared Neighborhood Hits	2
SwissProt Accessions	Q05860	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoforms I/II/III (Limb deformity protein).

Hits sorted by NC score

IRF8_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	25	Target Neighborhood Hits	25	Shared Neighborhood Hits	25
SwissProt Accessions	Q02556	Gene names	IRF8, ICSBP1
Domain Architecture
Description	Interferon regulatory factor 8 (IRF-8) (Interferon consensus sequence- binding protein) (ICSBP).

IRF8_MOUSE
NC score	0.998158 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	25	Target Neighborhood Hits	31	Shared Neighborhood Hits	21
SwissProt Accessions	P23611	Gene names	Irf8, Icsbp, Icsbp1
Domain Architecture
Description	Interferon regulatory factor 8 (IRF-8) (Interferon consensus sequence- binding protein) (ICSBP).

IRF4_MOUSE
NC score	0.967237 (rank : 3)	θ value	4.21644e-82 (rank : 3)
Query Neighborhood Hits	25	Target Neighborhood Hits	27	Shared Neighborhood Hits	18
SwissProt Accessions	Q64287, Q60802	Gene names	Irf4, Spip
Domain Architecture
Description	Interferon regulatory factor 4 (IRF-4) (Lymphocyte-specific interferon regulatory factor) (LSIRF) (NF-EM5) (PU.1 interaction partner) (Transcriptional activator PIP).

IRF4_HUMAN
NC score	0.965254 (rank : 4)	θ value	5.50685e-82 (rank : 4)
Query Neighborhood Hits	25	Target Neighborhood Hits	31	Shared Neighborhood Hits	18
SwissProt Accessions	Q15306, Q99660	Gene names	IRF4, MUM1
Domain Architecture
Description	Interferon regulatory factor 4 (IRF-4) (Lymphocyte-specific interferon regulatory factor) (LSIRF) (NF-EM5) (Multiple myeloma oncogene 1).

IRTF_HUMAN
NC score	0.951533 (rank : 5)	θ value	5.19021e-56 (rank : 6)
Query Neighborhood Hits	25	Target Neighborhood Hits	41	Shared Neighborhood Hits	18
SwissProt Accessions	Q00978	Gene names	ISGF3G, IRF9
Domain Architecture
Description	Transcriptional regulator ISGF3 subunit gamma (Interferon regulatory factor 9) (IRF-9) (IFN-alpha-responsive transcription factor subunit) (Interferon-stimulated gene factor 3 gamma) (ISGF3 p48 subunit) (ISGF- 3 gamma).

IRTF_MOUSE
NC score	0.947928 (rank : 6)	θ value	2.94036e-59 (rank : 5)
Query Neighborhood Hits	25	Target Neighborhood Hits	26	Shared Neighborhood Hits	18
SwissProt Accessions	Q61179	Gene names	Isgf3g
Domain Architecture
Description	Transcriptional regulator ISGF3 subunit gamma (IFN-alpha-responsive transcription factor subunit) (Interferon-stimulated gene factor 3 gamma) (ISGF3 p48 subunit) (ISGF-3 gamma).

IRF6_MOUSE
NC score	0.930699 (rank : 7)	θ value	5.37103e-53 (rank : 9)
Query Neighborhood Hits	25	Target Neighborhood Hits	26	Shared Neighborhood Hits	18
SwissProt Accessions	P97431	Gene names	Irf6
Domain Architecture
Description	Interferon regulatory factor 6 (IRF-6).

IRF6_HUMAN
NC score	0.930665 (rank : 8)	θ value	5.37103e-53 (rank : 8)
Query Neighborhood Hits	25	Target Neighborhood Hits	30	Shared Neighborhood Hits	18
SwissProt Accessions	O14896	Gene names	IRF6
Domain Architecture
Description	Interferon regulatory factor 6 (IRF-6).

IRF5_MOUSE
NC score	0.926846 (rank : 9)	θ value	3.71957e-54 (rank : 7)
Query Neighborhood Hits	25	Target Neighborhood Hits	49	Shared Neighborhood Hits	18
SwissProt Accessions	P56477	Gene names	Irf5
Domain Architecture
Description	Interferon regulatory factor 5 (IRF-5).

IRF5_HUMAN
NC score	0.925403 (rank : 10)	θ value	5.55816e-50 (rank : 10)
Query Neighborhood Hits	25	Target Neighborhood Hits	41	Shared Neighborhood Hits	18
SwissProt Accessions	Q13568, Q9BQF0	Gene names	IRF5
Domain Architecture
Description	Interferon regulatory factor 5 (IRF-5).

IRF3_MOUSE
NC score	0.868473 (rank : 11)	θ value	7.30988e-26 (rank : 16)
Query Neighborhood Hits	25	Target Neighborhood Hits	25	Shared Neighborhood Hits	18
SwissProt Accessions	P70671	Gene names	Irf3
Domain Architecture
Description	Interferon regulatory factor 3 (IRF-3).

IRF1_HUMAN
NC score	0.864427 (rank : 12)	θ value	1.92365e-26 (rank : 14)
Query Neighborhood Hits	25	Target Neighborhood Hits	26	Shared Neighborhood Hits	18
SwissProt Accessions	P10914, Q96GG7	Gene names	IRF1
Domain Architecture
Description	Interferon regulatory factor 1 (IRF-1).

IRF7_MOUSE
NC score	0.862165 (rank : 13)	θ value	1.47289e-26 (rank : 13)
Query Neighborhood Hits	25	Target Neighborhood Hits	34	Shared Neighborhood Hits	18
SwissProt Accessions	P70434	Gene names	Irf7
Domain Architecture
Description	Interferon regulatory factor 7 (IRF-7).

IRF3_HUMAN
NC score	0.860701 (rank : 14)	θ value	1.08979e-29 (rank : 11)
Query Neighborhood Hits	25	Target Neighborhood Hits	129	Shared Neighborhood Hits	18
SwissProt Accessions	Q14653	Gene names	IRF3
Domain Architecture
Description	Interferon regulatory factor 3 (IRF-3).

IRF1_MOUSE
NC score	0.859782 (rank : 15)	θ value	1.24688e-25 (rank : 17)
Query Neighborhood Hits	25	Target Neighborhood Hits	27	Shared Neighborhood Hits	18
SwissProt Accessions	P15314	Gene names	Irf1
Domain Architecture
Description	Interferon regulatory factor 1 (IRF-1).

IRF2_HUMAN
NC score	0.857920 (rank : 16)	θ value	2.51237e-26 (rank : 15)
Query Neighborhood Hits	25	Target Neighborhood Hits	35	Shared Neighborhood Hits	18
SwissProt Accessions	P14316, Q96B99	Gene names	IRF2
Domain Architecture
Description	Interferon regulatory factor 2 (IRF-2).

IRF2_MOUSE
NC score	0.855631 (rank : 17)	θ value	1.12775e-26 (rank : 12)
Query Neighborhood Hits	25	Target Neighborhood Hits	49	Shared Neighborhood Hits	18
SwissProt Accessions	P23906	Gene names	Irf2
Domain Architecture
Description	Interferon regulatory factor 2 (IRF-2).

IRF7_HUMAN
NC score	0.827928 (rank : 18)	θ value	1.24977e-17 (rank : 18)
Query Neighborhood Hits	25	Target Neighborhood Hits	73	Shared Neighborhood Hits	18
SwissProt Accessions	Q92985, O00331, O00332, O00333, O75924	Gene names	IRF7
Domain Architecture
Description	Interferon regulatory factor 7 (IRF-7).

FA62A_HUMAN
NC score	0.014256 (rank : 19)	θ value	3.0926 (rank : 21)
Query Neighborhood Hits	25	Target Neighborhood Hits	168	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BSJ8, O94848, Q6PJN4, Q9H6J1, Q9H6W2, Q9Y416	Gene names	FAM62A, KIAA0747, MBC2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

FBSH_HUMAN
NC score	0.011055 (rank : 20)	θ value	6.88961 (rank : 24)
Query Neighborhood Hits	25	Target Neighborhood Hits	46	Shared Neighborhood Hits	2
SwissProt Accessions	Q9HAH7, Q96CI9, Q9H9X4	Gene names	FBS1, FBS
Domain Architecture	No domain graphic available
Description	Probable fibrosin-1 long transcript protein.

TAI12_MOUSE
NC score	0.009277 (rank : 21)	θ value	5.27518 (rank : 23)
Query Neighborhood Hits	25	Target Neighborhood Hits	34	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BGQ2, Q3UIH1	Gene names	Taip12
Domain Architecture	No domain graphic available
Description	TGF-beta-induced apoptosis protein 12 (TAIP-12).

IPF1_MOUSE
NC score	0.009204 (rank : 22)	θ value	1.06291 (rank : 19)
Query Neighborhood Hits	25	Target Neighborhood Hits	340	Shared Neighborhood Hits	3
SwissProt Accessions	P52946	Gene names	Ipf1, Pdx1
Domain Architecture
Description	Insulin promoter factor 1 (IPF-1) (Islet/duodenum homeobox 1) (IDX-1) (Somatostatin-transactivating factor 1) (STF-1) (Pancreas/duodenum homeobox 1).

FMN1A_MOUSE
NC score	0.005332 (rank : 23)	θ value	6.88961 (rank : 25)
Query Neighborhood Hits	25	Target Neighborhood Hits	423	Shared Neighborhood Hits	2
SwissProt Accessions	Q05860	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoforms I/II/III (Limb deformity protein).

PCDA5_HUMAN
NC score	0.004369 (rank : 24)	θ value	4.03905 (rank : 22)
Query Neighborhood Hits	25	Target Neighborhood Hits	217	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y5H7, O75284, Q8N4R3	Gene names	PCDHA5
Domain Architecture
Description	Protocadherin alpha 5 precursor (PCDH-alpha5).

ANK3_HUMAN
NC score	0.002825 (rank : 25)	θ value	2.36792 (rank : 20)
Query Neighborhood Hits	25	Target Neighborhood Hits	853	Shared Neighborhood Hits	2
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).