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Network neighborhood for query Sequence : CPXM1_HUMAN

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CPXM1_HUMAN
SwissProt Accessions	Q96SM3, Q6P4G8, Q6UW65, Q9NUB5	Gene names	CPXM1, CPX1, CPXM
Domain Architecture
Description	Probable carboxypeptidase X1 precursor (EC 3.4.17.-) (Metallocarboxypeptidase CPX-1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CPXM1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	69	Target Neighborhood Hits	69	Shared Neighborhood Hits	69
SwissProt Accessions	Q96SM3, Q6P4G8, Q6UW65, Q9NUB5	Gene names	CPXM1, CPX1, CPXM
Domain Architecture
Description	Probable carboxypeptidase X1 precursor (EC 3.4.17.-) (Metallocarboxypeptidase CPX-1).

CPXM1_MOUSE
θ value	0 (rank : 2)	NC score	0.997373 (rank : 2)
Query Neighborhood Hits	69	Target Neighborhood Hits	63	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Z100, Q99LA3	Gene names	Cpxm1, Cpx1, Cpxm
Domain Architecture
Description	Probable carboxypeptidase X1 precursor (EC 3.4.17.-) (Metallocarboxypeptidase CPX-1).

CPXM2_HUMAN
θ value	0 (rank : 3)	NC score	0.990065 (rank : 4)
Query Neighborhood Hits	69	Target Neighborhood Hits	84	Shared Neighborhood Hits	52
SwissProt Accessions	Q8N436	Gene names	CPXM2
Domain Architecture
Description	Carboxypeptidase-like protein X2 precursor.

CPXM2_MOUSE
θ value	0 (rank : 4)	NC score	0.990666 (rank : 3)
Query Neighborhood Hits	69	Target Neighborhood Hits	58	Shared Neighborhood Hits	52
SwissProt Accessions	Q9D2L5, O54860, Q8VDQ4	Gene names	Cpxm2, Cpx2
Domain Architecture
Description	Carboxypeptidase-like protein X2 precursor.

CBPE_MOUSE
θ value	1.39067e-109 (rank : 5)	NC score	0.878648 (rank : 7)
Query Neighborhood Hits	69	Target Neighborhood Hits	29	Shared Neighborhood Hits	23
SwissProt Accessions	Q00493, Q64439	Gene names	Cpe
Domain Architecture
Description	Carboxypeptidase E precursor (EC 3.4.17.10) (CPE) (Carboxypeptidase H) (CPH) (Enkephalin convertase) (Prohormone-processing carboxypeptidase).

CBPE_HUMAN
θ value	3.0981e-109 (rank : 6)	NC score	0.878590 (rank : 8)
Query Neighborhood Hits	69	Target Neighborhood Hits	28	Shared Neighborhood Hits	23
SwissProt Accessions	P16870, Q9UIU9	Gene names	CPE
Domain Architecture
Description	Carboxypeptidase E precursor (EC 3.4.17.10) (CPE) (Carboxypeptidase H) (CPH) (Enkephalin convertase) (Prohormone-processing carboxypeptidase).

CBPZ_HUMAN
θ value	1.30163e-107 (rank : 7)	NC score	0.790153 (rank : 14)
Query Neighborhood Hits	69	Target Neighborhood Hits	69	Shared Neighborhood Hits	25
SwissProt Accessions	Q66K79, O00520, Q96MX2	Gene names	CPZ
Domain Architecture	No domain graphic available
Description	Carboxypeptidase Z precursor (EC 3.4.17.-) (CPZ).

CBPZ_MOUSE
θ value	6.45994e-107 (rank : 8)	NC score	0.806005 (rank : 13)
Query Neighborhood Hits	69	Target Neighborhood Hits	77	Shared Neighborhood Hits	25
SwissProt Accessions	Q8R4V4	Gene names	Cpz
Domain Architecture	No domain graphic available
Description	Carboxypeptidase Z precursor (EC 3.4.17.-) (CPZ).

CBPN_HUMAN
θ value	2.07809e-105 (rank : 9)	NC score	0.879841 (rank : 5)
Query Neighborhood Hits	69	Target Neighborhood Hits	32	Shared Neighborhood Hits	26
SwissProt Accessions	P15169	Gene names	CPN1, ACBP
Domain Architecture
Description	Carboxypeptidase N catalytic chain precursor (EC 3.4.17.3) (CPN) (Carboxypeptidase N polypeptide 1) (Carboxypeptidase N small subunit) (Lysine carboxypeptidase) (Arginine carboxypeptidase) (Kininase-1) (Serum carboxypeptidase N) (SCPN) (Anaphylatoxin inactivator) (Plasma carboxypeptidase B).

CBPN_MOUSE
θ value	1.75921e-104 (rank : 10)	NC score	0.879445 (rank : 6)
Query Neighborhood Hits	69	Target Neighborhood Hits	26	Shared Neighborhood Hits	23
SwissProt Accessions	Q9JJN5, Q91WM9	Gene names	Cpn1
Domain Architecture	No domain graphic available
Description	Carboxypeptidase N catalytic chain precursor (EC 3.4.17.3) (CPN) (Carboxypeptidase N polypeptide 1) (Carboxypeptidase N small subunit).

CBPD_MOUSE
θ value	2.81514e-94 (rank : 11)	NC score	0.844853 (rank : 12)
Query Neighborhood Hits	69	Target Neighborhood Hits	62	Shared Neighborhood Hits	27
SwissProt Accessions	O89001	Gene names	Cpd
Domain Architecture
Description	Carboxypeptidase D precursor (EC 3.4.17.22) (Metallocarboxypeptidase D) (gp180).

CBPD_HUMAN
θ value	2.38316e-93 (rank : 12)	NC score	0.844918 (rank : 11)
Query Neighborhood Hits	69	Target Neighborhood Hits	53	Shared Neighborhood Hits	27
SwissProt Accessions	O75976, O15377, Q86SH9, Q86XE6	Gene names	CPD
Domain Architecture
Description	Carboxypeptidase D precursor (EC 3.4.17.22) (Metallocarboxypeptidase D) (gp180).

CBPM_MOUSE
θ value	1.5555e-68 (rank : 13)	NC score	0.857771 (rank : 9)
Query Neighborhood Hits	69	Target Neighborhood Hits	30	Shared Neighborhood Hits	27
SwissProt Accessions	Q80V42, Q497S5, Q9CYH8	Gene names	Cpm
Domain Architecture	No domain graphic available
Description	Carboxypeptidase M precursor (EC 3.4.17.12) (CPM).

CBPM_HUMAN
θ value	1.6097e-65 (rank : 14)	NC score	0.857662 (rank : 10)
Query Neighborhood Hits	69	Target Neighborhood Hits	33	Shared Neighborhood Hits	27
SwissProt Accessions	P14384, Q9H2K9	Gene names	CPM
Domain Architecture
Description	Carboxypeptidase M precursor (EC 3.4.17.12) (CPM).

MFGM_HUMAN
θ value	7.82807e-20 (rank : 15)	NC score	0.518597 (rank : 17)
Query Neighborhood Hits	69	Target Neighborhood Hits	150	Shared Neighborhood Hits	31
SwissProt Accessions	Q08431	Gene names	MFGE8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (HMFG) (Breast epithelial antigen BA46) (MFGM) [Contains: Lactadherin short form; Medin].

EDIL3_MOUSE
θ value	1.02238e-19 (rank : 16)	NC score	0.362083 (rank : 31)
Query Neighborhood Hits	69	Target Neighborhood Hits	317	Shared Neighborhood Hits	32
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

MFGM_MOUSE
θ value	1.74391e-19 (rank : 17)	NC score	0.449669 (rank : 18)
Query Neighborhood Hits	69	Target Neighborhood Hits	233	Shared Neighborhood Hits	31
SwissProt Accessions	P21956, P97800, Q3TBN5, Q9R1X9, Q9WTS3	Gene names	Mfge8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (MFGM) (Sperm surface protein SP47) (MP47).

EDIL3_HUMAN
θ value	6.62687e-19 (rank : 18)	NC score	0.367580 (rank : 27)
Query Neighborhood Hits	69	Target Neighborhood Hits	292	Shared Neighborhood Hits	32
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

XLRS1_MOUSE
θ value	9.56915e-18 (rank : 19)	NC score	0.577953 (rank : 15)
Query Neighborhood Hits	69	Target Neighborhood Hits	32	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Z1L4	Gene names	Rs1, Rs1h, Xlrs1
Domain Architecture
Description	Retinoschisin precursor (X-linked juvenile retinoschisis protein homolog).

XLRS1_HUMAN
θ value	3.63628e-17 (rank : 20)	NC score	0.576018 (rank : 16)
Query Neighborhood Hits	69	Target Neighborhood Hits	32	Shared Neighborhood Hits	31
SwissProt Accessions	O15537	Gene names	RS1, XLRS1
Domain Architecture
Description	Retinoschisin precursor (X-linked juvenile retinoschisis protein).

FA5_HUMAN
θ value	3.07829e-16 (rank : 21)	NC score	0.445552 (rank : 19)
Query Neighborhood Hits	69	Target Neighborhood Hits	172	Shared Neighborhood Hits	31
SwissProt Accessions	P12259, Q14285, Q6UPU6	Gene names	F5
Domain Architecture
Description	Coagulation factor V precursor (Activated protein C cofactor) [Contains: Coagulation factor V heavy chain; Coagulation factor V light chain].

FA8_HUMAN
θ value	1.16975e-15 (rank : 22)	NC score	0.442074 (rank : 21)
Query Neighborhood Hits	69	Target Neighborhood Hits	112	Shared Neighborhood Hits	32
SwissProt Accessions	P00451	Gene names	F8, F8C
Domain Architecture
Description	Coagulation factor VIII precursor (Procoagulant component) (Antihemophilic factor) (AHF) [Contains: Factor VIIIa heavy chain, 200 kDa isoform; Factor VIIIa heavy chain, 92 kDa isoform; Factor VIII B chain; Factor VIIIa light chain].

FA8_MOUSE
θ value	1.52774e-15 (rank : 23)	NC score	0.442625 (rank : 20)
Query Neighborhood Hits	69	Target Neighborhood Hits	100	Shared Neighborhood Hits	31
SwissProt Accessions	Q06194	Gene names	F8, Cf8, F8c
Domain Architecture
Description	Coagulation factor VIII precursor (Procoagulant component).

CNTP2_MOUSE
θ value	9.90251e-15 (rank : 24)	NC score	0.368365 (rank : 26)
Query Neighborhood Hits	69	Target Neighborhood Hits	194	Shared Neighborhood Hits	31
SwissProt Accessions	Q9CPW0, Q6P2K4, Q6ZQ31	Gene names	Cntnap2, Kiaa0868
Domain Architecture	No domain graphic available
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

CNTP2_HUMAN
θ value	1.68911e-14 (rank : 25)	NC score	0.374746 (rank : 25)
Query Neighborhood Hits	69	Target Neighborhood Hits	199	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UHC6, Q52LV1, Q5H9Q7, Q9UQ12	Gene names	CNTNAP2, CASPR2, KIAA0868
Domain Architecture
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

NRP2_HUMAN
θ value	1.68911e-14 (rank : 26)	NC score	0.364294 (rank : 29)
Query Neighborhood Hits	69	Target Neighborhood Hits	120	Shared Neighborhood Hits	32
SwissProt Accessions	O60462, O14820, O14821	Gene names	NRP2, VEGF165R2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

NRP2_MOUSE
θ value	4.91457e-14 (rank : 27)	NC score	0.364740 (rank : 28)
Query Neighborhood Hits	69	Target Neighborhood Hits	113	Shared Neighborhood Hits	32
SwissProt Accessions	O35375, O35373, O35374, O35376, O35377, O35378	Gene names	Nrp2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

DCBD2_HUMAN
θ value	4.16044e-13 (rank : 28)	NC score	0.410855 (rank : 24)
Query Neighborhood Hits	69	Target Neighborhood Hits	118	Shared Neighborhood Hits	32
SwissProt Accessions	Q96PD2, Q8N6M4, Q8TDX2	Gene names	DCBLD2, CLCP1, ESDN
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein) (CUB, LCCL and coagulation factor V/VIII-homology domains protein 1).

DCBD2_MOUSE
θ value	4.16044e-13 (rank : 29)	NC score	0.424364 (rank : 22)
Query Neighborhood Hits	69	Target Neighborhood Hits	113	Shared Neighborhood Hits	32
SwissProt Accessions	Q91ZV3, Q8BKI4	Gene names	Dcbld2, Esdn
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein).

CNTP3_HUMAN
θ value	2.0648e-12 (rank : 30)	NC score	0.363582 (rank : 30)
Query Neighborhood Hits	69	Target Neighborhood Hits	195	Shared Neighborhood Hits	31
SwissProt Accessions	Q9BZ76, Q9C0E9	Gene names	CNTNAP3, CASPR3, KIAA1714
Domain Architecture
Description	Contactin-associated protein-like 3 precursor (Cell recognition molecule Caspr3).

NRP1_HUMAN
θ value	1.74796e-11 (rank : 31)	NC score	0.351479 (rank : 32)
Query Neighborhood Hits	69	Target Neighborhood Hits	119	Shared Neighborhood Hits	32
SwissProt Accessions	O14786, O60461, Q96IH5	Gene names	NRP1, NRP, VEGF165R
Domain Architecture
Description	Neuropilin-1 precursor (Vascular endothelial cell growth factor 165 receptor) (CD304 antigen).

DDR2_HUMAN
θ value	3.89403e-11 (rank : 32)	NC score	0.130787 (rank : 54)
Query Neighborhood Hits	69	Target Neighborhood Hits	818	Shared Neighborhood Hits	32
SwissProt Accessions	Q16832	Gene names	DDR2, NTRKR3, TKT, TYRO10
Domain Architecture
Description	Discoidin domain-containing receptor 2 precursor (EC 2.7.10.1) (Discoidin domain receptor 2) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO 10) (Neurotrophic tyrosine kinase, receptor-related 3) (CD167b antigen).

DDR2_MOUSE
θ value	3.89403e-11 (rank : 33)	NC score	0.131890 (rank : 53)
Query Neighborhood Hits	69	Target Neighborhood Hits	813	Shared Neighborhood Hits	32
SwissProt Accessions	Q62371	Gene names	Ddr2, Ntrkr3, Tkt, Tyro10
Domain Architecture
Description	Discoidin domain-containing receptor 2 precursor (EC 2.7.10.1) (Discoidin domain receptor 2) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO 10) (Neurotrophic tyrosine kinase, receptor-related 3) (CD167b antigen).

DDR1_HUMAN
θ value	6.64225e-11 (rank : 34)	NC score	0.121572 (rank : 55)
Query Neighborhood Hits	69	Target Neighborhood Hits	819	Shared Neighborhood Hits	31
SwissProt Accessions	Q08345, Q14196, Q16562, Q5ST12, Q9UD37	Gene names	DDR1, CAK, EDDR1, RTK6, TRKE
Domain Architecture
Description	Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (TRK E) (Protein-tyrosine kinase RTK 6) (HGK2) (CD167a antigen).

DCBD1_HUMAN
θ value	1.133e-10 (rank : 35)	NC score	0.413157 (rank : 23)
Query Neighborhood Hits	69	Target Neighborhood Hits	110	Shared Neighborhood Hits	32
SwissProt Accessions	Q8N8Z6, Q5H992, Q8IYK5, Q8N7L9, Q96NH2	Gene names	DCBLD1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

NRP1_MOUSE
θ value	1.133e-10 (rank : 36)	NC score	0.349112 (rank : 34)
Query Neighborhood Hits	69	Target Neighborhood Hits	120	Shared Neighborhood Hits	32
SwissProt Accessions	P97333	Gene names	Nrp1, Nrp
Domain Architecture
Description	Neuropilin-1 precursor (A5 protein).

CNTP4_MOUSE
θ value	9.59137e-10 (rank : 37)	NC score	0.349995 (rank : 33)
Query Neighborhood Hits	69	Target Neighborhood Hits	193	Shared Neighborhood Hits	31
SwissProt Accessions	Q99P47	Gene names	Cntnap4, Caspr4
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

CNTP4_HUMAN
θ value	8.11959e-09 (rank : 38)	NC score	0.346843 (rank : 35)
Query Neighborhood Hits	69	Target Neighborhood Hits	187	Shared Neighborhood Hits	32
SwissProt Accessions	Q9C0A0	Gene names	CNTNAP4, CASPR4, KIAA1763
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

DDR1_MOUSE
θ value	1.06045e-08 (rank : 39)	NC score	0.115395 (rank : 56)
Query Neighborhood Hits	69	Target Neighborhood Hits	818	Shared Neighborhood Hits	31
SwissProt Accessions	Q03146	Gene names	Ddr1, Cak, Eddr1, Mpk6
Domain Architecture
Description	Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (Protein-tyrosine kinase MPK-6) (CD167a antigen).

CNTP1_MOUSE
θ value	1.80886e-08 (rank : 40)	NC score	0.340278 (rank : 36)
Query Neighborhood Hits	69	Target Neighborhood Hits	183	Shared Neighborhood Hits	31
SwissProt Accessions	O54991	Gene names	Cntnap1, Nrxn4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (Paranodin) (NCP1) (MHDNIV).

CBPA4_HUMAN
θ value	2.36244e-08 (rank : 41)	NC score	0.321561 (rank : 38)
Query Neighborhood Hits	69	Target Neighborhood Hits	33	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UI42, Q86UY9	Gene names	CPA4, CPA3
Domain Architecture
Description	Carboxypeptidase A4 precursor (EC 3.4.17.-) (Carboxypeptidase A3).

CBPA6_MOUSE
θ value	2.36244e-08 (rank : 42)	NC score	0.283374 (rank : 40)
Query Neighborhood Hits	69	Target Neighborhood Hits	31	Shared Neighborhood Hits	27
SwissProt Accessions	Q5U901, Q8BVD0	Gene names	Cpa6
Domain Architecture	No domain graphic available
Description	Carboxypeptidase A6 precursor (EC 3.4.17.1).

CNTP1_HUMAN
θ value	2.36244e-08 (rank : 43)	NC score	0.339766 (rank : 37)
Query Neighborhood Hits	69	Target Neighborhood Hits	196	Shared Neighborhood Hits	31
SwissProt Accessions	P78357	Gene names	CNTNAP1, CASPR, NRXN4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (p190).

CBPB2_MOUSE
θ value	2.21117e-06 (rank : 44)	NC score	0.292798 (rank : 39)
Query Neighborhood Hits	69	Target Neighborhood Hits	36	Shared Neighborhood Hits	27
SwissProt Accessions	Q9JHH6, Q5EBI3, Q9QZF0	Gene names	Cpb2, Tafi
Domain Architecture	No domain graphic available
Description	Carboxypeptidase B2 precursor (EC 3.4.17.20) (Carboxypeptidase U) (CPU) (Thrombin-activable fibrinolysis inhibitor) (TAFI) (Carboxypeptidase R) (CPR).

CBPA6_HUMAN
θ value	6.43352e-06 (rank : 45)	NC score	0.269262 (rank : 42)
Query Neighborhood Hits	69	Target Neighborhood Hits	31	Shared Neighborhood Hits	27
SwissProt Accessions	Q8N4T0, Q8NEX8, Q8TDE8, Q9NRI9	Gene names	CPA6, CPAH
Domain Architecture
Description	Carboxypeptidase A6 precursor (EC 3.4.17.1) (Carboxypeptidase B).

CBPA4_MOUSE
θ value	2.44474e-05 (rank : 46)	NC score	0.280554 (rank : 41)
Query Neighborhood Hits	69	Target Neighborhood Hits	35	Shared Neighborhood Hits	27
SwissProt Accessions	Q6P8K8, Q8BMK6, Q9CTE6	Gene names	Cpa4
Domain Architecture	No domain graphic available
Description	Carboxypeptidase A4 precursor (EC 3.4.17.-).

CBPB2_HUMAN
θ value	5.44631e-05 (rank : 47)	NC score	0.249810 (rank : 44)
Query Neighborhood Hits	69	Target Neighborhood Hits	32	Shared Neighborhood Hits	25
SwissProt Accessions	Q96IY4, Q15114, Q5T9K1, Q5T9K2, Q9P2Y6	Gene names	CPB2
Domain Architecture	No domain graphic available
Description	Carboxypeptidase B2 precursor (EC 3.4.17.20) (Carboxypeptidase U) (CPU) (Thrombin-activable fibrinolysis inhibitor) (TAFI) (Plasma carboxypeptidase B) (pCPB).

CBPA3_MOUSE
θ value	0.000158464 (rank : 48)	NC score	0.221833 (rank : 45)
Query Neighborhood Hits	69	Target Neighborhood Hits	47	Shared Neighborhood Hits	27
SwissProt Accessions	P15089	Gene names	Cpa3
Domain Architecture
Description	Mast cell carboxypeptidase A precursor (EC 3.4.17.1) (MC-CPA) (Carboxypeptidase A3).

CBPA3_HUMAN
θ value	0.00228821 (rank : 49)	NC score	0.214515 (rank : 47)
Query Neighborhood Hits	69	Target Neighborhood Hits	41	Shared Neighborhood Hits	27
SwissProt Accessions	P15088, Q96E94	Gene names	CPA3
Domain Architecture
Description	Mast cell carboxypeptidase A precursor (EC 3.4.17.1) (MC-CPA) (Carboxypeptidase A3).

CBPA2_HUMAN
θ value	0.00390308 (rank : 50)	NC score	0.256427 (rank : 43)
Query Neighborhood Hits	69	Target Neighborhood Hits	33	Shared Neighborhood Hits	27
SwissProt Accessions	P48052, Q96A12, Q96QN3	Gene names	CPA2
Domain Architecture
Description	Carboxypeptidase A2 precursor (EC 3.4.17.15).

CBPB1_HUMAN
θ value	0.0736092 (rank : 51)	NC score	0.188548 (rank : 49)
Query Neighborhood Hits	69	Target Neighborhood Hits	26	Shared Neighborhood Hits	22
SwissProt Accessions	P15086, O60834, Q96BQ8	Gene names	CPB1, CPB, PCPB
Domain Architecture
Description	Carboxypeptidase B precursor (EC 3.4.17.2) (Pancreas-specific protein) (PASP).

CBPO_HUMAN
θ value	0.62314 (rank : 52)	NC score	0.192764 (rank : 48)
Query Neighborhood Hits	69	Target Neighborhood Hits	30	Shared Neighborhood Hits	23
SwissProt Accessions	Q8IVL8, Q2M277, Q7RTW7	Gene names	CPO
Domain Architecture	No domain graphic available
Description	Carboxypeptidase O precursor (EC 3.4.17.-) (CPO).

ENTK_MOUSE
θ value	0.62314 (rank : 53)	NC score	0.019539 (rank : 84)
Query Neighborhood Hits	69	Target Neighborhood Hits	338	Shared Neighborhood Hits	10
SwissProt Accessions	P97435	Gene names	Prss7, Entk
Domain Architecture
Description	Enteropeptidase (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

TRIM8_MOUSE
θ value	1.06291 (rank : 54)	NC score	0.007179 (rank : 90)
Query Neighborhood Hits	69	Target Neighborhood Hits	674	Shared Neighborhood Hits	4
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

CSPG5_MOUSE
θ value	1.38821 (rank : 55)	NC score	0.020761 (rank : 83)
Query Neighborhood Hits	69	Target Neighborhood Hits	211	Shared Neighborhood Hits	5
SwissProt Accessions	Q71M36, Q71M37, Q7TNT8, Q8BPJ5, Q9QY32	Gene names	Cspg5, Caleb, Ngc
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 5 precursor (Neuroglycan C) (Acidic leucine-rich EGF-like domain-containing brain protein).

CBPA1_HUMAN
θ value	3.0926 (rank : 56)	NC score	0.162257 (rank : 52)
Query Neighborhood Hits	69	Target Neighborhood Hits	31	Shared Neighborhood Hits	21
SwissProt Accessions	P15085, Q9BS67	Gene names	CPA1, CPA
Domain Architecture
Description	Carboxypeptidase A1 precursor (EC 3.4.17.1).

FOXC2_HUMAN
θ value	3.0926 (rank : 57)	NC score	0.002276 (rank : 93)
Query Neighborhood Hits	69	Target Neighborhood Hits	236	Shared Neighborhood Hits	2
SwissProt Accessions	Q99958	Gene names	FOXC2, FKHL14, MFH1
Domain Architecture
Description	Forkhead box protein C2 (Forkhead-related protein FKHL14) (Mesenchyme fork head protein 1) (MFH-1 protein) (Transcription factor FKH-14).

PCD12_HUMAN
θ value	3.0926 (rank : 58)	NC score	0.000290 (rank : 95)
Query Neighborhood Hits	69	Target Neighborhood Hits	203	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NPG4, Q6UXB6, Q96KB8, Q9H7Y6, Q9H8E0	Gene names	PCDH12
Domain Architecture
Description	Protocadherin-12 precursor (Vascular cadherin-2) (Vascular endothelial cadherin-2) (VE-cadherin-2) (VE-cad-2).

CBPA1_MOUSE
θ value	4.03905 (rank : 59)	NC score	0.163008 (rank : 51)
Query Neighborhood Hits	69	Target Neighborhood Hits	25	Shared Neighborhood Hits	21
SwissProt Accessions	Q7TPZ8	Gene names	Cpa1
Domain Architecture	No domain graphic available
Description	Carboxypeptidase A1 precursor (EC 3.4.17.1).

MATN3_HUMAN
θ value	4.03905 (rank : 60)	NC score	0.001008 (rank : 94)
Query Neighborhood Hits	69	Target Neighborhood Hits	268	Shared Neighborhood Hits	2
SwissProt Accessions	O15232	Gene names	MATN3
Domain Architecture
Description	Matrilin-3 precursor.

PRGC2_MOUSE
θ value	4.03905 (rank : 61)	NC score	0.008364 (rank : 88)
Query Neighborhood Hits	69	Target Neighborhood Hits	225	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VHJ7, Q8C1C0	Gene names	Ppargc1b, Errl1, Pgc1, Pgc1b, Ppargc1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta protein) (PGC-1beta) (ERR ligand 1) (PPARGC-1-beta) (PGC-1-beta).

PTC2_HUMAN
θ value	4.03905 (rank : 62)	NC score	0.006859 (rank : 91)
Query Neighborhood Hits	69	Target Neighborhood Hits	63	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y6C5, O95341, O95856, Q5QP87, Q6UX14	Gene names	PTCH2
Domain Architecture
Description	Protein patched homolog 2 (PTC2).

TARA_HUMAN
θ value	4.03905 (rank : 63)	NC score	-0.000537 (rank : 96)
Query Neighborhood Hits	69	Target Neighborhood Hits	1626	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TRIM8_HUMAN
θ value	4.03905 (rank : 64)	NC score	0.005538 (rank : 92)
Query Neighborhood Hits	69	Target Neighborhood Hits	650	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TROAP_HUMAN
θ value	4.03905 (rank : 65)	NC score	0.010927 (rank : 87)
Query Neighborhood Hits	69	Target Neighborhood Hits	258	Shared Neighborhood Hits	2
SwissProt Accessions	Q12815	Gene names	TROAP
Domain Architecture	No domain graphic available
Description	Trophinin-associated protein (Tastin) (Trophinin-assisting protein).

ZN318_HUMAN
θ value	4.03905 (rank : 66)	NC score	0.008191 (rank : 89)
Query Neighborhood Hits	69	Target Neighborhood Hits	497	Shared Neighborhood Hits	6
SwissProt Accessions	Q5VUA4, O94796, Q4G0E4, Q8NEM6, Q9UNU8, Q9Y2W9	Gene names	ZNF318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Endocrine regulatory protein).

SSF1_MOUSE
θ value	5.27518 (rank : 67)	NC score	0.016690 (rank : 86)
Query Neighborhood Hits	69	Target Neighborhood Hits	99	Shared Neighborhood Hits	4
SwissProt Accessions	Q91YU8	Gene names	Ppan
Domain Architecture
Description	Suppressor of SWI4 1 homolog (Ssf-1) (Peter Pan homolog).

NKX12_MOUSE
θ value	6.88961 (rank : 68)	NC score	-0.000979 (rank : 97)
Query Neighborhood Hits	69	Target Neighborhood Hits	332	Shared Neighborhood Hits	2
SwissProt Accessions	P42580, Q9JHF2, Q9JKW5, Q9JKW6, Q9JKW9, Q9JKX0, Q9JKX1	Gene names	Nkx1-2, Nkx1.1, Sax1
Domain Architecture
Description	NK1 transcription factor-related protein 2 (Homeobox protein SAX-1) (NKX-1.1).

SSF1_HUMAN
θ value	6.88961 (rank : 69)	NC score	0.016876 (rank : 85)
Query Neighborhood Hits	69	Target Neighborhood Hits	33	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NQ55, Q9BW97, Q9H170	Gene names	PPAN, SSF1
Domain Architecture
Description	Suppressor of SWI4 1 homolog (Ssf-1) (Peter Pan homolog).

CBPA5_HUMAN
θ value	θ > 10 (rank : 70)	NC score	0.186849 (rank : 50)
Query Neighborhood Hits	69	Target Neighborhood Hits	28	Shared Neighborhood Hits	21
SwissProt Accessions	Q8WXQ8, Q86SE2, Q86XM3, Q8NA08	Gene names	CPA5
Domain Architecture
Description	Carboxypeptidase A5 precursor (EC 3.4.17.1).

CBPA5_MOUSE
θ value	θ > 10 (rank : 71)	NC score	0.219339 (rank : 46)
Query Neighborhood Hits	69	Target Neighborhood Hits	27	Shared Neighborhood Hits	23
SwissProt Accessions	Q8R4H4	Gene names	Cpa5
Domain Architecture
Description	Carboxypeptidase A5 precursor (EC 3.4.17.1).

CERU_HUMAN
θ value	θ > 10 (rank : 72)	NC score	0.078425 (rank : 60)
Query Neighborhood Hits	69	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	P00450, Q14063, Q2PP18, Q9UKS4	Gene names	CP
Domain Architecture
Description	Ceruloplasmin precursor (EC 1.16.3.1) (Ferroxidase).

CERU_MOUSE
θ value	θ > 10 (rank : 73)	NC score	0.077628 (rank : 62)
Query Neighborhood Hits	69	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	Q61147	Gene names	Cp
Domain Architecture
Description	Ceruloplasmin precursor (EC 1.16.3.1) (Ferroxidase).

CUBN_HUMAN
θ value	θ > 10 (rank : 74)	NC score	0.050747 (rank : 79)
Query Neighborhood Hits	69	Target Neighborhood Hits	482	Shared Neighborhood Hits	21
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

CUBN_MOUSE
θ value	θ > 10 (rank : 75)	NC score	0.050484 (rank : 81)
Query Neighborhood Hits	69	Target Neighborhood Hits	477	Shared Neighborhood Hits	20
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

CUZD1_HUMAN
θ value	θ > 10 (rank : 76)	NC score	0.050408 (rank : 82)
Query Neighborhood Hits	69	Target Neighborhood Hits	89	Shared Neighborhood Hits	7
SwissProt Accessions	Q86UP6, Q7Z660, Q7Z661, Q86SG1, Q86UP5, Q9HAR7	Gene names	CUZD1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Transmembrane protein UO-44).

DCBD1_MOUSE
θ value	θ > 10 (rank : 77)	NC score	0.098672 (rank : 57)
Query Neighborhood Hits	69	Target Neighborhood Hits	89	Shared Neighborhood Hits	8
SwissProt Accessions	Q9D4J3, Q8R327, Q9D696	Gene names	Dcbld1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

GLPC_HUMAN
θ value	θ > 10 (rank : 78)	NC score	0.088511 (rank : 58)
Query Neighborhood Hits	69	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	P04921, Q92642	Gene names	GYPC, GPC
Domain Architecture
Description	Glycophorin C (PAS-2') (Glycoprotein beta) (GLPC) (Glycoconnectin) (Sialoglycoprotein D) (Glycophorin D) (GPD) (CD236 antigen).

HEPH_HUMAN
θ value	θ > 10 (rank : 79)	NC score	0.077949 (rank : 61)
Query Neighborhood Hits	69	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BQS7, O75180, Q6UW45, Q9C058	Gene names	HEPH, KIAA0698
Domain Architecture	No domain graphic available
Description	Hephaestin precursor (EC 1.-.-.-).

HEPH_MOUSE
θ value	θ > 10 (rank : 80)	NC score	0.079007 (rank : 59)
Query Neighborhood Hits	69	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z0Z4, Q6ZQ65, Q80Y80, Q8C4S2	Gene names	Heph, Kiaa0698
Domain Architecture	No domain graphic available
Description	Hephaestin precursor (EC 1.-.-.-).

MFRP_HUMAN
θ value	θ > 10 (rank : 81)	NC score	0.068152 (rank : 67)
Query Neighborhood Hits	69	Target Neighborhood Hits	165	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BY79, Q335M3, Q96DQ9	Gene names	MFRP
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

MFRP_MOUSE
θ value	θ > 10 (rank : 82)	NC score	0.069322 (rank : 66)
Query Neighborhood Hits	69	Target Neighborhood Hits	166	Shared Neighborhood Hits	10
SwissProt Accessions	Q8K480, Q8BPP4	Gene names	Mfrp
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

NETO1_HUMAN
θ value	θ > 10 (rank : 83)	NC score	0.053536 (rank : 78)
Query Neighborhood Hits	69	Target Neighborhood Hits	110	Shared Neighborhood Hits	8
SwissProt Accessions	Q8TDF5, Q86W85, Q8ND78, Q8TDF4	Gene names	NETO1, BTCL1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

NETO1_MOUSE
θ value	θ > 10 (rank : 84)	NC score	0.055084 (rank : 77)
Query Neighborhood Hits	69	Target Neighborhood Hits	109	Shared Neighborhood Hits	8
SwissProt Accessions	Q8R4I7, Q80X39, Q8C4S3, Q8CCM2	Gene names	Neto1, Btcl1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

NETO2_HUMAN
θ value	θ > 10 (rank : 85)	NC score	0.057666 (rank : 73)
Query Neighborhood Hits	69	Target Neighborhood Hits	109	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NC67, Q7Z381, Q8ND51, Q96SP4, Q9NVY8	Gene names	NETO2, BTCL2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

NETO2_MOUSE
θ value	θ > 10 (rank : 86)	NC score	0.056608 (rank : 74)
Query Neighborhood Hits	69	Target Neighborhood Hits	113	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BNJ6, Q5VM49, Q8C4Q8	Gene names	Neto2, Btcl2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

NRX1A_HUMAN
θ value	θ > 10 (rank : 87)	NC score	0.073288 (rank : 63)
Query Neighborhood Hits	69	Target Neighborhood Hits	170	Shared Neighborhood Hits	11
SwissProt Accessions	Q9ULB1, O60323, Q53TJ9, Q53TQ1, Q9C079, Q9C080, Q9C081, Q9H3M2, Q9UDM6	Gene names	NRXN1, KIAA0578
Domain Architecture
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

NRX1A_MOUSE
θ value	θ > 10 (rank : 88)	NC score	0.072363 (rank : 64)
Query Neighborhood Hits	69	Target Neighborhood Hits	164	Shared Neighborhood Hits	11
SwissProt Accessions	Q9CS84, O88722, Q80Y87, Q8CHE6	Gene names	Nrxn1, Kiaa0578
Domain Architecture	No domain graphic available
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

NRX2A_HUMAN
θ value	θ > 10 (rank : 89)	NC score	0.061890 (rank : 72)
Query Neighborhood Hits	69	Target Neighborhood Hits	614	Shared Neighborhood Hits	11
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

NRX3A_HUMAN
θ value	θ > 10 (rank : 90)	NC score	0.071421 (rank : 65)
Query Neighborhood Hits	69	Target Neighborhood Hits	164	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y4C0, O95378, Q9NS47, Q9P1V3, Q9P1V6, Q9UIE2, Q9UIE3, Q9ULA5, Q9Y486	Gene names	NRXN3, KIAA0743
Domain Architecture
Description	Neurexin-3-alpha precursor (Neurexin III-alpha).

PCOC1_HUMAN
θ value	θ > 10 (rank : 91)	NC score	0.063654 (rank : 71)
Query Neighborhood Hits	69	Target Neighborhood Hits	146	Shared Neighborhood Hits	8
SwissProt Accessions	Q15113, O14550	Gene names	PCOLCE, PCPE1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein).

PCOC1_MOUSE
θ value	θ > 10 (rank : 92)	NC score	0.064853 (rank : 69)
Query Neighborhood Hits	69	Target Neighborhood Hits	100	Shared Neighborhood Hits	8
SwissProt Accessions	Q61398, O35113	Gene names	Pcolce, Pcpe1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein) (P14).

PCOC2_HUMAN
θ value	θ > 10 (rank : 93)	NC score	0.063716 (rank : 70)
Query Neighborhood Hits	69	Target Neighborhood Hits	73	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UKZ9, Q9BRH3	Gene names	PCOLCE2, PCPE2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

PCOC2_MOUSE
θ value	θ > 10 (rank : 94)	NC score	0.065521 (rank : 68)
Query Neighborhood Hits	69	Target Neighborhood Hits	73	Shared Neighborhood Hits	8
SwissProt Accessions	Q8R4W6, Q3V1K6, Q9CX06	Gene names	Pcolce2, Pcpe2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

PDGFD_HUMAN
θ value	θ > 10 (rank : 95)	NC score	0.050518 (rank : 80)
Query Neighborhood Hits	69	Target Neighborhood Hits	74	Shared Neighborhood Hits	8
SwissProt Accessions	Q9GZP0, Q9BWV5	Gene names	PDGFD, IEGF, SCDGFB
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor D precursor (PDGF D) (Iris-expressed growth factor) (Spinal cord-derived growth factor B) (SCDGF-B).

TSG6_HUMAN
θ value	θ > 10 (rank : 96)	NC score	0.056320 (rank : 76)
Query Neighborhood Hits	69	Target Neighborhood Hits	91	Shared Neighborhood Hits	8
SwissProt Accessions	P98066, Q8WWI9	Gene names	TNFAIP6, TSG6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein) (Hyaluronate-binding protein).

TSG6_MOUSE
θ value	θ > 10 (rank : 97)	NC score	0.056576 (rank : 75)
Query Neighborhood Hits	69	Target Neighborhood Hits	91	Shared Neighborhood Hits	8
SwissProt Accessions	O08859	Gene names	Tnfaip6, Tnfip6, Tsg6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein).

Hits sorted by NC score

CPXM1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	69	Target Neighborhood Hits	69	Shared Neighborhood Hits	69
SwissProt Accessions	Q96SM3, Q6P4G8, Q6UW65, Q9NUB5	Gene names	CPXM1, CPX1, CPXM
Domain Architecture
Description	Probable carboxypeptidase X1 precursor (EC 3.4.17.-) (Metallocarboxypeptidase CPX-1).

CPXM1_MOUSE
NC score	0.997373 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	69	Target Neighborhood Hits	63	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Z100, Q99LA3	Gene names	Cpxm1, Cpx1, Cpxm
Domain Architecture
Description	Probable carboxypeptidase X1 precursor (EC 3.4.17.-) (Metallocarboxypeptidase CPX-1).

CPXM2_MOUSE
NC score	0.990666 (rank : 3)	θ value	0 (rank : 4)
Query Neighborhood Hits	69	Target Neighborhood Hits	58	Shared Neighborhood Hits	52
SwissProt Accessions	Q9D2L5, O54860, Q8VDQ4	Gene names	Cpxm2, Cpx2
Domain Architecture
Description	Carboxypeptidase-like protein X2 precursor.

CPXM2_HUMAN
NC score	0.990065 (rank : 4)	θ value	0 (rank : 3)
Query Neighborhood Hits	69	Target Neighborhood Hits	84	Shared Neighborhood Hits	52
SwissProt Accessions	Q8N436	Gene names	CPXM2
Domain Architecture
Description	Carboxypeptidase-like protein X2 precursor.

CBPN_HUMAN
NC score	0.879841 (rank : 5)	θ value	2.07809e-105 (rank : 9)
Query Neighborhood Hits	69	Target Neighborhood Hits	32	Shared Neighborhood Hits	26
SwissProt Accessions	P15169	Gene names	CPN1, ACBP
Domain Architecture
Description	Carboxypeptidase N catalytic chain precursor (EC 3.4.17.3) (CPN) (Carboxypeptidase N polypeptide 1) (Carboxypeptidase N small subunit) (Lysine carboxypeptidase) (Arginine carboxypeptidase) (Kininase-1) (Serum carboxypeptidase N) (SCPN) (Anaphylatoxin inactivator) (Plasma carboxypeptidase B).

CBPN_MOUSE
NC score	0.879445 (rank : 6)	θ value	1.75921e-104 (rank : 10)
Query Neighborhood Hits	69	Target Neighborhood Hits	26	Shared Neighborhood Hits	23
SwissProt Accessions	Q9JJN5, Q91WM9	Gene names	Cpn1
Domain Architecture	No domain graphic available
Description	Carboxypeptidase N catalytic chain precursor (EC 3.4.17.3) (CPN) (Carboxypeptidase N polypeptide 1) (Carboxypeptidase N small subunit).

CBPE_MOUSE
NC score	0.878648 (rank : 7)	θ value	1.39067e-109 (rank : 5)
Query Neighborhood Hits	69	Target Neighborhood Hits	29	Shared Neighborhood Hits	23
SwissProt Accessions	Q00493, Q64439	Gene names	Cpe
Domain Architecture
Description	Carboxypeptidase E precursor (EC 3.4.17.10) (CPE) (Carboxypeptidase H) (CPH) (Enkephalin convertase) (Prohormone-processing carboxypeptidase).

CBPE_HUMAN
NC score	0.878590 (rank : 8)	θ value	3.0981e-109 (rank : 6)
Query Neighborhood Hits	69	Target Neighborhood Hits	28	Shared Neighborhood Hits	23
SwissProt Accessions	P16870, Q9UIU9	Gene names	CPE
Domain Architecture
Description	Carboxypeptidase E precursor (EC 3.4.17.10) (CPE) (Carboxypeptidase H) (CPH) (Enkephalin convertase) (Prohormone-processing carboxypeptidase).

CBPM_MOUSE
NC score	0.857771 (rank : 9)	θ value	1.5555e-68 (rank : 13)
Query Neighborhood Hits	69	Target Neighborhood Hits	30	Shared Neighborhood Hits	27
SwissProt Accessions	Q80V42, Q497S5, Q9CYH8	Gene names	Cpm
Domain Architecture	No domain graphic available
Description	Carboxypeptidase M precursor (EC 3.4.17.12) (CPM).

CBPM_HUMAN
NC score	0.857662 (rank : 10)	θ value	1.6097e-65 (rank : 14)
Query Neighborhood Hits	69	Target Neighborhood Hits	33	Shared Neighborhood Hits	27
SwissProt Accessions	P14384, Q9H2K9	Gene names	CPM
Domain Architecture
Description	Carboxypeptidase M precursor (EC 3.4.17.12) (CPM).

CBPD_HUMAN
NC score	0.844918 (rank : 11)	θ value	2.38316e-93 (rank : 12)
Query Neighborhood Hits	69	Target Neighborhood Hits	53	Shared Neighborhood Hits	27
SwissProt Accessions	O75976, O15377, Q86SH9, Q86XE6	Gene names	CPD
Domain Architecture
Description	Carboxypeptidase D precursor (EC 3.4.17.22) (Metallocarboxypeptidase D) (gp180).

CBPD_MOUSE
NC score	0.844853 (rank : 12)	θ value	2.81514e-94 (rank : 11)
Query Neighborhood Hits	69	Target Neighborhood Hits	62	Shared Neighborhood Hits	27
SwissProt Accessions	O89001	Gene names	Cpd
Domain Architecture
Description	Carboxypeptidase D precursor (EC 3.4.17.22) (Metallocarboxypeptidase D) (gp180).

CBPZ_MOUSE
NC score	0.806005 (rank : 13)	θ value	6.45994e-107 (rank : 8)
Query Neighborhood Hits	69	Target Neighborhood Hits	77	Shared Neighborhood Hits	25
SwissProt Accessions	Q8R4V4	Gene names	Cpz
Domain Architecture	No domain graphic available
Description	Carboxypeptidase Z precursor (EC 3.4.17.-) (CPZ).

CBPZ_HUMAN
NC score	0.790153 (rank : 14)	θ value	1.30163e-107 (rank : 7)
Query Neighborhood Hits	69	Target Neighborhood Hits	69	Shared Neighborhood Hits	25
SwissProt Accessions	Q66K79, O00520, Q96MX2	Gene names	CPZ
Domain Architecture	No domain graphic available
Description	Carboxypeptidase Z precursor (EC 3.4.17.-) (CPZ).

XLRS1_MOUSE
NC score	0.577953 (rank : 15)	θ value	9.56915e-18 (rank : 19)
Query Neighborhood Hits	69	Target Neighborhood Hits	32	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Z1L4	Gene names	Rs1, Rs1h, Xlrs1
Domain Architecture
Description	Retinoschisin precursor (X-linked juvenile retinoschisis protein homolog).

XLRS1_HUMAN
NC score	0.576018 (rank : 16)	θ value	3.63628e-17 (rank : 20)
Query Neighborhood Hits	69	Target Neighborhood Hits	32	Shared Neighborhood Hits	31
SwissProt Accessions	O15537	Gene names	RS1, XLRS1
Domain Architecture
Description	Retinoschisin precursor (X-linked juvenile retinoschisis protein).

MFGM_HUMAN
NC score	0.518597 (rank : 17)	θ value	7.82807e-20 (rank : 15)
Query Neighborhood Hits	69	Target Neighborhood Hits	150	Shared Neighborhood Hits	31
SwissProt Accessions	Q08431	Gene names	MFGE8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (HMFG) (Breast epithelial antigen BA46) (MFGM) [Contains: Lactadherin short form; Medin].

MFGM_MOUSE
NC score	0.449669 (rank : 18)	θ value	1.74391e-19 (rank : 17)
Query Neighborhood Hits	69	Target Neighborhood Hits	233	Shared Neighborhood Hits	31
SwissProt Accessions	P21956, P97800, Q3TBN5, Q9R1X9, Q9WTS3	Gene names	Mfge8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (MFGM) (Sperm surface protein SP47) (MP47).

FA5_HUMAN
NC score	0.445552 (rank : 19)	θ value	3.07829e-16 (rank : 21)
Query Neighborhood Hits	69	Target Neighborhood Hits	172	Shared Neighborhood Hits	31
SwissProt Accessions	P12259, Q14285, Q6UPU6	Gene names	F5
Domain Architecture
Description	Coagulation factor V precursor (Activated protein C cofactor) [Contains: Coagulation factor V heavy chain; Coagulation factor V light chain].

FA8_MOUSE
NC score	0.442625 (rank : 20)	θ value	1.52774e-15 (rank : 23)
Query Neighborhood Hits	69	Target Neighborhood Hits	100	Shared Neighborhood Hits	31
SwissProt Accessions	Q06194	Gene names	F8, Cf8, F8c
Domain Architecture
Description	Coagulation factor VIII precursor (Procoagulant component).

FA8_HUMAN
NC score	0.442074 (rank : 21)	θ value	1.16975e-15 (rank : 22)
Query Neighborhood Hits	69	Target Neighborhood Hits	112	Shared Neighborhood Hits	32
SwissProt Accessions	P00451	Gene names	F8, F8C
Domain Architecture
Description	Coagulation factor VIII precursor (Procoagulant component) (Antihemophilic factor) (AHF) [Contains: Factor VIIIa heavy chain, 200 kDa isoform; Factor VIIIa heavy chain, 92 kDa isoform; Factor VIII B chain; Factor VIIIa light chain].

DCBD2_MOUSE
NC score	0.424364 (rank : 22)	θ value	4.16044e-13 (rank : 29)
Query Neighborhood Hits	69	Target Neighborhood Hits	113	Shared Neighborhood Hits	32
SwissProt Accessions	Q91ZV3, Q8BKI4	Gene names	Dcbld2, Esdn
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein).

DCBD1_HUMAN
NC score	0.413157 (rank : 23)	θ value	1.133e-10 (rank : 35)
Query Neighborhood Hits	69	Target Neighborhood Hits	110	Shared Neighborhood Hits	32
SwissProt Accessions	Q8N8Z6, Q5H992, Q8IYK5, Q8N7L9, Q96NH2	Gene names	DCBLD1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

DCBD2_HUMAN
NC score	0.410855 (rank : 24)	θ value	4.16044e-13 (rank : 28)
Query Neighborhood Hits	69	Target Neighborhood Hits	118	Shared Neighborhood Hits	32
SwissProt Accessions	Q96PD2, Q8N6M4, Q8TDX2	Gene names	DCBLD2, CLCP1, ESDN
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein) (CUB, LCCL and coagulation factor V/VIII-homology domains protein 1).

CNTP2_HUMAN
NC score	0.374746 (rank : 25)	θ value	1.68911e-14 (rank : 25)
Query Neighborhood Hits	69	Target Neighborhood Hits	199	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UHC6, Q52LV1, Q5H9Q7, Q9UQ12	Gene names	CNTNAP2, CASPR2, KIAA0868
Domain Architecture
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

CNTP2_MOUSE
NC score	0.368365 (rank : 26)	θ value	9.90251e-15 (rank : 24)
Query Neighborhood Hits	69	Target Neighborhood Hits	194	Shared Neighborhood Hits	31
SwissProt Accessions	Q9CPW0, Q6P2K4, Q6ZQ31	Gene names	Cntnap2, Kiaa0868
Domain Architecture	No domain graphic available
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

EDIL3_HUMAN
NC score	0.367580 (rank : 27)	θ value	6.62687e-19 (rank : 18)
Query Neighborhood Hits	69	Target Neighborhood Hits	292	Shared Neighborhood Hits	32
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

NRP2_MOUSE
NC score	0.364740 (rank : 28)	θ value	4.91457e-14 (rank : 27)
Query Neighborhood Hits	69	Target Neighborhood Hits	113	Shared Neighborhood Hits	32
SwissProt Accessions	O35375, O35373, O35374, O35376, O35377, O35378	Gene names	Nrp2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

NRP2_HUMAN
NC score	0.364294 (rank : 29)	θ value	1.68911e-14 (rank : 26)
Query Neighborhood Hits	69	Target Neighborhood Hits	120	Shared Neighborhood Hits	32
SwissProt Accessions	O60462, O14820, O14821	Gene names	NRP2, VEGF165R2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

CNTP3_HUMAN
NC score	0.363582 (rank : 30)	θ value	2.0648e-12 (rank : 30)
Query Neighborhood Hits	69	Target Neighborhood Hits	195	Shared Neighborhood Hits	31
SwissProt Accessions	Q9BZ76, Q9C0E9	Gene names	CNTNAP3, CASPR3, KIAA1714
Domain Architecture
Description	Contactin-associated protein-like 3 precursor (Cell recognition molecule Caspr3).

EDIL3_MOUSE
NC score	0.362083 (rank : 31)	θ value	1.02238e-19 (rank : 16)
Query Neighborhood Hits	69	Target Neighborhood Hits	317	Shared Neighborhood Hits	32
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

NRP1_HUMAN
NC score	0.351479 (rank : 32)	θ value	1.74796e-11 (rank : 31)
Query Neighborhood Hits	69	Target Neighborhood Hits	119	Shared Neighborhood Hits	32
SwissProt Accessions	O14786, O60461, Q96IH5	Gene names	NRP1, NRP, VEGF165R
Domain Architecture
Description	Neuropilin-1 precursor (Vascular endothelial cell growth factor 165 receptor) (CD304 antigen).

CNTP4_MOUSE
NC score	0.349995 (rank : 33)	θ value	9.59137e-10 (rank : 37)
Query Neighborhood Hits	69	Target Neighborhood Hits	193	Shared Neighborhood Hits	31
SwissProt Accessions	Q99P47	Gene names	Cntnap4, Caspr4
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

NRP1_MOUSE
NC score	0.349112 (rank : 34)	θ value	1.133e-10 (rank : 36)
Query Neighborhood Hits	69	Target Neighborhood Hits	120	Shared Neighborhood Hits	32
SwissProt Accessions	P97333	Gene names	Nrp1, Nrp
Domain Architecture
Description	Neuropilin-1 precursor (A5 protein).

CNTP4_HUMAN
NC score	0.346843 (rank : 35)	θ value	8.11959e-09 (rank : 38)
Query Neighborhood Hits	69	Target Neighborhood Hits	187	Shared Neighborhood Hits	32
SwissProt Accessions	Q9C0A0	Gene names	CNTNAP4, CASPR4, KIAA1763
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

CNTP1_MOUSE
NC score	0.340278 (rank : 36)	θ value	1.80886e-08 (rank : 40)
Query Neighborhood Hits	69	Target Neighborhood Hits	183	Shared Neighborhood Hits	31
SwissProt Accessions	O54991	Gene names	Cntnap1, Nrxn4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (Paranodin) (NCP1) (MHDNIV).

CNTP1_HUMAN
NC score	0.339766 (rank : 37)	θ value	2.36244e-08 (rank : 43)
Query Neighborhood Hits	69	Target Neighborhood Hits	196	Shared Neighborhood Hits	31
SwissProt Accessions	P78357	Gene names	CNTNAP1, CASPR, NRXN4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (p190).

CBPA4_HUMAN
NC score	0.321561 (rank : 38)	θ value	2.36244e-08 (rank : 41)
Query Neighborhood Hits	69	Target Neighborhood Hits	33	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UI42, Q86UY9	Gene names	CPA4, CPA3
Domain Architecture
Description	Carboxypeptidase A4 precursor (EC 3.4.17.-) (Carboxypeptidase A3).

CBPB2_MOUSE
NC score	0.292798 (rank : 39)	θ value	2.21117e-06 (rank : 44)
Query Neighborhood Hits	69	Target Neighborhood Hits	36	Shared Neighborhood Hits	27
SwissProt Accessions	Q9JHH6, Q5EBI3, Q9QZF0	Gene names	Cpb2, Tafi
Domain Architecture	No domain graphic available
Description	Carboxypeptidase B2 precursor (EC 3.4.17.20) (Carboxypeptidase U) (CPU) (Thrombin-activable fibrinolysis inhibitor) (TAFI) (Carboxypeptidase R) (CPR).

CBPA6_MOUSE
NC score	0.283374 (rank : 40)	θ value	2.36244e-08 (rank : 42)
Query Neighborhood Hits	69	Target Neighborhood Hits	31	Shared Neighborhood Hits	27
SwissProt Accessions	Q5U901, Q8BVD0	Gene names	Cpa6
Domain Architecture	No domain graphic available
Description	Carboxypeptidase A6 precursor (EC 3.4.17.1).

CBPA4_MOUSE
NC score	0.280554 (rank : 41)	θ value	2.44474e-05 (rank : 46)
Query Neighborhood Hits	69	Target Neighborhood Hits	35	Shared Neighborhood Hits	27
SwissProt Accessions	Q6P8K8, Q8BMK6, Q9CTE6	Gene names	Cpa4
Domain Architecture	No domain graphic available
Description	Carboxypeptidase A4 precursor (EC 3.4.17.-).

CBPA6_HUMAN
NC score	0.269262 (rank : 42)	θ value	6.43352e-06 (rank : 45)
Query Neighborhood Hits	69	Target Neighborhood Hits	31	Shared Neighborhood Hits	27
SwissProt Accessions	Q8N4T0, Q8NEX8, Q8TDE8, Q9NRI9	Gene names	CPA6, CPAH
Domain Architecture
Description	Carboxypeptidase A6 precursor (EC 3.4.17.1) (Carboxypeptidase B).

CBPA2_HUMAN
NC score	0.256427 (rank : 43)	θ value	0.00390308 (rank : 50)
Query Neighborhood Hits	69	Target Neighborhood Hits	33	Shared Neighborhood Hits	27
SwissProt Accessions	P48052, Q96A12, Q96QN3	Gene names	CPA2
Domain Architecture
Description	Carboxypeptidase A2 precursor (EC 3.4.17.15).

CBPB2_HUMAN
NC score	0.249810 (rank : 44)	θ value	5.44631e-05 (rank : 47)
Query Neighborhood Hits	69	Target Neighborhood Hits	32	Shared Neighborhood Hits	25
SwissProt Accessions	Q96IY4, Q15114, Q5T9K1, Q5T9K2, Q9P2Y6	Gene names	CPB2
Domain Architecture	No domain graphic available
Description	Carboxypeptidase B2 precursor (EC 3.4.17.20) (Carboxypeptidase U) (CPU) (Thrombin-activable fibrinolysis inhibitor) (TAFI) (Plasma carboxypeptidase B) (pCPB).

CBPA3_MOUSE
NC score	0.221833 (rank : 45)	θ value	0.000158464 (rank : 48)
Query Neighborhood Hits	69	Target Neighborhood Hits	47	Shared Neighborhood Hits	27
SwissProt Accessions	P15089	Gene names	Cpa3
Domain Architecture
Description	Mast cell carboxypeptidase A precursor (EC 3.4.17.1) (MC-CPA) (Carboxypeptidase A3).

CBPA5_MOUSE
NC score	0.219339 (rank : 46)	θ value	θ > 10 (rank : 71)
Query Neighborhood Hits	69	Target Neighborhood Hits	27	Shared Neighborhood Hits	23
SwissProt Accessions	Q8R4H4	Gene names	Cpa5
Domain Architecture
Description	Carboxypeptidase A5 precursor (EC 3.4.17.1).

CBPA3_HUMAN
NC score	0.214515 (rank : 47)	θ value	0.00228821 (rank : 49)
Query Neighborhood Hits	69	Target Neighborhood Hits	41	Shared Neighborhood Hits	27
SwissProt Accessions	P15088, Q96E94	Gene names	CPA3
Domain Architecture
Description	Mast cell carboxypeptidase A precursor (EC 3.4.17.1) (MC-CPA) (Carboxypeptidase A3).

CBPO_HUMAN
NC score	0.192764 (rank : 48)	θ value	0.62314 (rank : 52)
Query Neighborhood Hits	69	Target Neighborhood Hits	30	Shared Neighborhood Hits	23
SwissProt Accessions	Q8IVL8, Q2M277, Q7RTW7	Gene names	CPO
Domain Architecture	No domain graphic available
Description	Carboxypeptidase O precursor (EC 3.4.17.-) (CPO).

CBPB1_HUMAN
NC score	0.188548 (rank : 49)	θ value	0.0736092 (rank : 51)
Query Neighborhood Hits	69	Target Neighborhood Hits	26	Shared Neighborhood Hits	22
SwissProt Accessions	P15086, O60834, Q96BQ8	Gene names	CPB1, CPB, PCPB
Domain Architecture
Description	Carboxypeptidase B precursor (EC 3.4.17.2) (Pancreas-specific protein) (PASP).

CBPA5_HUMAN
NC score	0.186849 (rank : 50)	θ value	θ > 10 (rank : 70)
Query Neighborhood Hits	69	Target Neighborhood Hits	28	Shared Neighborhood Hits	21
SwissProt Accessions	Q8WXQ8, Q86SE2, Q86XM3, Q8NA08	Gene names	CPA5
Domain Architecture
Description	Carboxypeptidase A5 precursor (EC 3.4.17.1).

CBPA1_MOUSE
NC score	0.163008 (rank : 51)	θ value	4.03905 (rank : 59)
Query Neighborhood Hits	69	Target Neighborhood Hits	25	Shared Neighborhood Hits	21
SwissProt Accessions	Q7TPZ8	Gene names	Cpa1
Domain Architecture	No domain graphic available
Description	Carboxypeptidase A1 precursor (EC 3.4.17.1).

CBPA1_HUMAN
NC score	0.162257 (rank : 52)	θ value	3.0926 (rank : 56)
Query Neighborhood Hits	69	Target Neighborhood Hits	31	Shared Neighborhood Hits	21
SwissProt Accessions	P15085, Q9BS67	Gene names	CPA1, CPA
Domain Architecture
Description	Carboxypeptidase A1 precursor (EC 3.4.17.1).

DDR2_MOUSE
NC score	0.131890 (rank : 53)	θ value	3.89403e-11 (rank : 33)
Query Neighborhood Hits	69	Target Neighborhood Hits	813	Shared Neighborhood Hits	32
SwissProt Accessions	Q62371	Gene names	Ddr2, Ntrkr3, Tkt, Tyro10
Domain Architecture
Description	Discoidin domain-containing receptor 2 precursor (EC 2.7.10.1) (Discoidin domain receptor 2) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO 10) (Neurotrophic tyrosine kinase, receptor-related 3) (CD167b antigen).

DDR2_HUMAN
NC score	0.130787 (rank : 54)	θ value	3.89403e-11 (rank : 32)
Query Neighborhood Hits	69	Target Neighborhood Hits	818	Shared Neighborhood Hits	32
SwissProt Accessions	Q16832	Gene names	DDR2, NTRKR3, TKT, TYRO10
Domain Architecture
Description	Discoidin domain-containing receptor 2 precursor (EC 2.7.10.1) (Discoidin domain receptor 2) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO 10) (Neurotrophic tyrosine kinase, receptor-related 3) (CD167b antigen).

DDR1_HUMAN
NC score	0.121572 (rank : 55)	θ value	6.64225e-11 (rank : 34)
Query Neighborhood Hits	69	Target Neighborhood Hits	819	Shared Neighborhood Hits	31
SwissProt Accessions	Q08345, Q14196, Q16562, Q5ST12, Q9UD37	Gene names	DDR1, CAK, EDDR1, RTK6, TRKE
Domain Architecture
Description	Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (TRK E) (Protein-tyrosine kinase RTK 6) (HGK2) (CD167a antigen).

DDR1_MOUSE
NC score	0.115395 (rank : 56)	θ value	1.06045e-08 (rank : 39)
Query Neighborhood Hits	69	Target Neighborhood Hits	818	Shared Neighborhood Hits	31
SwissProt Accessions	Q03146	Gene names	Ddr1, Cak, Eddr1, Mpk6
Domain Architecture
Description	Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (Protein-tyrosine kinase MPK-6) (CD167a antigen).

DCBD1_MOUSE
NC score	0.098672 (rank : 57)	θ value	θ > 10 (rank : 77)
Query Neighborhood Hits	69	Target Neighborhood Hits	89	Shared Neighborhood Hits	8
SwissProt Accessions	Q9D4J3, Q8R327, Q9D696	Gene names	Dcbld1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

GLPC_HUMAN
NC score	0.088511 (rank : 58)	θ value	θ > 10 (rank : 78)
Query Neighborhood Hits	69	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	P04921, Q92642	Gene names	GYPC, GPC
Domain Architecture
Description	Glycophorin C (PAS-2') (Glycoprotein beta) (GLPC) (Glycoconnectin) (Sialoglycoprotein D) (Glycophorin D) (GPD) (CD236 antigen).

HEPH_MOUSE
NC score	0.079007 (rank : 59)	θ value	θ > 10 (rank : 80)
Query Neighborhood Hits	69	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z0Z4, Q6ZQ65, Q80Y80, Q8C4S2	Gene names	Heph, Kiaa0698
Domain Architecture	No domain graphic available
Description	Hephaestin precursor (EC 1.-.-.-).

CERU_HUMAN
NC score	0.078425 (rank : 60)	θ value	θ > 10 (rank : 72)
Query Neighborhood Hits	69	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	P00450, Q14063, Q2PP18, Q9UKS4	Gene names	CP
Domain Architecture
Description	Ceruloplasmin precursor (EC 1.16.3.1) (Ferroxidase).

HEPH_HUMAN
NC score	0.077949 (rank : 61)	θ value	θ > 10 (rank : 79)
Query Neighborhood Hits	69	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BQS7, O75180, Q6UW45, Q9C058	Gene names	HEPH, KIAA0698
Domain Architecture	No domain graphic available
Description	Hephaestin precursor (EC 1.-.-.-).

CERU_MOUSE
NC score	0.077628 (rank : 62)	θ value	θ > 10 (rank : 73)
Query Neighborhood Hits	69	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	Q61147	Gene names	Cp
Domain Architecture
Description	Ceruloplasmin precursor (EC 1.16.3.1) (Ferroxidase).

NRX1A_HUMAN
NC score	0.073288 (rank : 63)	θ value	θ > 10 (rank : 87)
Query Neighborhood Hits	69	Target Neighborhood Hits	170	Shared Neighborhood Hits	11
SwissProt Accessions	Q9ULB1, O60323, Q53TJ9, Q53TQ1, Q9C079, Q9C080, Q9C081, Q9H3M2, Q9UDM6	Gene names	NRXN1, KIAA0578
Domain Architecture
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

NRX1A_MOUSE
NC score	0.072363 (rank : 64)	θ value	θ > 10 (rank : 88)
Query Neighborhood Hits	69	Target Neighborhood Hits	164	Shared Neighborhood Hits	11
SwissProt Accessions	Q9CS84, O88722, Q80Y87, Q8CHE6	Gene names	Nrxn1, Kiaa0578
Domain Architecture	No domain graphic available
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

NRX3A_HUMAN
NC score	0.071421 (rank : 65)	θ value	θ > 10 (rank : 90)
Query Neighborhood Hits	69	Target Neighborhood Hits	164	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y4C0, O95378, Q9NS47, Q9P1V3, Q9P1V6, Q9UIE2, Q9UIE3, Q9ULA5, Q9Y486	Gene names	NRXN3, KIAA0743
Domain Architecture
Description	Neurexin-3-alpha precursor (Neurexin III-alpha).

MFRP_MOUSE
NC score	0.069322 (rank : 66)	θ value	θ > 10 (rank : 82)
Query Neighborhood Hits	69	Target Neighborhood Hits	166	Shared Neighborhood Hits	10
SwissProt Accessions	Q8K480, Q8BPP4	Gene names	Mfrp
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

MFRP_HUMAN
NC score	0.068152 (rank : 67)	θ value	θ > 10 (rank : 81)
Query Neighborhood Hits	69	Target Neighborhood Hits	165	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BY79, Q335M3, Q96DQ9	Gene names	MFRP
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

PCOC2_MOUSE
NC score	0.065521 (rank : 68)	θ value	θ > 10 (rank : 94)
Query Neighborhood Hits	69	Target Neighborhood Hits	73	Shared Neighborhood Hits	8
SwissProt Accessions	Q8R4W6, Q3V1K6, Q9CX06	Gene names	Pcolce2, Pcpe2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

PCOC1_MOUSE
NC score	0.064853 (rank : 69)	θ value	θ > 10 (rank : 92)
Query Neighborhood Hits	69	Target Neighborhood Hits	100	Shared Neighborhood Hits	8
SwissProt Accessions	Q61398, O35113	Gene names	Pcolce, Pcpe1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein) (P14).

PCOC2_HUMAN
NC score	0.063716 (rank : 70)	θ value	θ > 10 (rank : 93)
Query Neighborhood Hits	69	Target Neighborhood Hits	73	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UKZ9, Q9BRH3	Gene names	PCOLCE2, PCPE2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

PCOC1_HUMAN
NC score	0.063654 (rank : 71)	θ value	θ > 10 (rank : 91)
Query Neighborhood Hits	69	Target Neighborhood Hits	146	Shared Neighborhood Hits	8
SwissProt Accessions	Q15113, O14550	Gene names	PCOLCE, PCPE1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein).

NRX2A_HUMAN
NC score	0.061890 (rank : 72)	θ value	θ > 10 (rank : 89)
Query Neighborhood Hits	69	Target Neighborhood Hits	614	Shared Neighborhood Hits	11
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

NETO2_HUMAN
NC score	0.057666 (rank : 73)	θ value	θ > 10 (rank : 85)
Query Neighborhood Hits	69	Target Neighborhood Hits	109	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NC67, Q7Z381, Q8ND51, Q96SP4, Q9NVY8	Gene names	NETO2, BTCL2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

NETO2_MOUSE
NC score	0.056608 (rank : 74)	θ value	θ > 10 (rank : 86)
Query Neighborhood Hits	69	Target Neighborhood Hits	113	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BNJ6, Q5VM49, Q8C4Q8	Gene names	Neto2, Btcl2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

TSG6_MOUSE
NC score	0.056576 (rank : 75)	θ value	θ > 10 (rank : 97)
Query Neighborhood Hits	69	Target Neighborhood Hits	91	Shared Neighborhood Hits	8
SwissProt Accessions	O08859	Gene names	Tnfaip6, Tnfip6, Tsg6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein).

TSG6_HUMAN
NC score	0.056320 (rank : 76)	θ value	θ > 10 (rank : 96)
Query Neighborhood Hits	69	Target Neighborhood Hits	91	Shared Neighborhood Hits	8
SwissProt Accessions	P98066, Q8WWI9	Gene names	TNFAIP6, TSG6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein) (Hyaluronate-binding protein).

NETO1_MOUSE
NC score	0.055084 (rank : 77)	θ value	θ > 10 (rank : 84)
Query Neighborhood Hits	69	Target Neighborhood Hits	109	Shared Neighborhood Hits	8
SwissProt Accessions	Q8R4I7, Q80X39, Q8C4S3, Q8CCM2	Gene names	Neto1, Btcl1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

NETO1_HUMAN
NC score	0.053536 (rank : 78)	θ value	θ > 10 (rank : 83)
Query Neighborhood Hits	69	Target Neighborhood Hits	110	Shared Neighborhood Hits	8
SwissProt Accessions	Q8TDF5, Q86W85, Q8ND78, Q8TDF4	Gene names	NETO1, BTCL1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

CUBN_HUMAN
NC score	0.050747 (rank : 79)	θ value	θ > 10 (rank : 74)
Query Neighborhood Hits	69	Target Neighborhood Hits	482	Shared Neighborhood Hits	21
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

PDGFD_HUMAN
NC score	0.050518 (rank : 80)	θ value	θ > 10 (rank : 95)
Query Neighborhood Hits	69	Target Neighborhood Hits	74	Shared Neighborhood Hits	8
SwissProt Accessions	Q9GZP0, Q9BWV5	Gene names	PDGFD, IEGF, SCDGFB
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor D precursor (PDGF D) (Iris-expressed growth factor) (Spinal cord-derived growth factor B) (SCDGF-B).

CUBN_MOUSE
NC score	0.050484 (rank : 81)	θ value	θ > 10 (rank : 75)
Query Neighborhood Hits	69	Target Neighborhood Hits	477	Shared Neighborhood Hits	20
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

CUZD1_HUMAN
NC score	0.050408 (rank : 82)	θ value	θ > 10 (rank : 76)
Query Neighborhood Hits	69	Target Neighborhood Hits	89	Shared Neighborhood Hits	7
SwissProt Accessions	Q86UP6, Q7Z660, Q7Z661, Q86SG1, Q86UP5, Q9HAR7	Gene names	CUZD1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Transmembrane protein UO-44).

CSPG5_MOUSE
NC score	0.020761 (rank : 83)	θ value	1.38821 (rank : 55)
Query Neighborhood Hits	69	Target Neighborhood Hits	211	Shared Neighborhood Hits	5
SwissProt Accessions	Q71M36, Q71M37, Q7TNT8, Q8BPJ5, Q9QY32	Gene names	Cspg5, Caleb, Ngc
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 5 precursor (Neuroglycan C) (Acidic leucine-rich EGF-like domain-containing brain protein).

ENTK_MOUSE
NC score	0.019539 (rank : 84)	θ value	0.62314 (rank : 53)
Query Neighborhood Hits	69	Target Neighborhood Hits	338	Shared Neighborhood Hits	10
SwissProt Accessions	P97435	Gene names	Prss7, Entk
Domain Architecture
Description	Enteropeptidase (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

SSF1_HUMAN
NC score	0.016876 (rank : 85)	θ value	6.88961 (rank : 69)
Query Neighborhood Hits	69	Target Neighborhood Hits	33	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NQ55, Q9BW97, Q9H170	Gene names	PPAN, SSF1
Domain Architecture
Description	Suppressor of SWI4 1 homolog (Ssf-1) (Peter Pan homolog).

SSF1_MOUSE
NC score	0.016690 (rank : 86)	θ value	5.27518 (rank : 67)
Query Neighborhood Hits	69	Target Neighborhood Hits	99	Shared Neighborhood Hits	4
SwissProt Accessions	Q91YU8	Gene names	Ppan
Domain Architecture
Description	Suppressor of SWI4 1 homolog (Ssf-1) (Peter Pan homolog).

TROAP_HUMAN
NC score	0.010927 (rank : 87)	θ value	4.03905 (rank : 65)
Query Neighborhood Hits	69	Target Neighborhood Hits	258	Shared Neighborhood Hits	2
SwissProt Accessions	Q12815	Gene names	TROAP
Domain Architecture	No domain graphic available
Description	Trophinin-associated protein (Tastin) (Trophinin-assisting protein).

PRGC2_MOUSE
NC score	0.008364 (rank : 88)	θ value	4.03905 (rank : 61)
Query Neighborhood Hits	69	Target Neighborhood Hits	225	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VHJ7, Q8C1C0	Gene names	Ppargc1b, Errl1, Pgc1, Pgc1b, Ppargc1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta protein) (PGC-1beta) (ERR ligand 1) (PPARGC-1-beta) (PGC-1-beta).

ZN318_HUMAN
NC score	0.008191 (rank : 89)	θ value	4.03905 (rank : 66)
Query Neighborhood Hits	69	Target Neighborhood Hits	497	Shared Neighborhood Hits	6
SwissProt Accessions	Q5VUA4, O94796, Q4G0E4, Q8NEM6, Q9UNU8, Q9Y2W9	Gene names	ZNF318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Endocrine regulatory protein).

TRIM8_MOUSE
NC score	0.007179 (rank : 90)	θ value	1.06291 (rank : 54)
Query Neighborhood Hits	69	Target Neighborhood Hits	674	Shared Neighborhood Hits	4
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

PTC2_HUMAN
NC score	0.006859 (rank : 91)	θ value	4.03905 (rank : 62)
Query Neighborhood Hits	69	Target Neighborhood Hits	63	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y6C5, O95341, O95856, Q5QP87, Q6UX14	Gene names	PTCH2
Domain Architecture
Description	Protein patched homolog 2 (PTC2).

TRIM8_HUMAN
NC score	0.005538 (rank : 92)	θ value	4.03905 (rank : 64)
Query Neighborhood Hits	69	Target Neighborhood Hits	650	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

FOXC2_HUMAN
NC score	0.002276 (rank : 93)	θ value	3.0926 (rank : 57)
Query Neighborhood Hits	69	Target Neighborhood Hits	236	Shared Neighborhood Hits	2
SwissProt Accessions	Q99958	Gene names	FOXC2, FKHL14, MFH1
Domain Architecture
Description	Forkhead box protein C2 (Forkhead-related protein FKHL14) (Mesenchyme fork head protein 1) (MFH-1 protein) (Transcription factor FKH-14).

MATN3_HUMAN
NC score	0.001008 (rank : 94)	θ value	4.03905 (rank : 60)
Query Neighborhood Hits	69	Target Neighborhood Hits	268	Shared Neighborhood Hits	2
SwissProt Accessions	O15232	Gene names	MATN3
Domain Architecture
Description	Matrilin-3 precursor.

PCD12_HUMAN
NC score	0.000290 (rank : 95)	θ value	3.0926 (rank : 58)
Query Neighborhood Hits	69	Target Neighborhood Hits	203	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NPG4, Q6UXB6, Q96KB8, Q9H7Y6, Q9H8E0	Gene names	PCDH12
Domain Architecture
Description	Protocadherin-12 precursor (Vascular cadherin-2) (Vascular endothelial cadherin-2) (VE-cadherin-2) (VE-cad-2).

TARA_HUMAN
NC score	-0.000537 (rank : 96)	θ value	4.03905 (rank : 63)
Query Neighborhood Hits	69	Target Neighborhood Hits	1626	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

NKX12_MOUSE
NC score	-0.000979 (rank : 97)	θ value	6.88961 (rank : 68)
Query Neighborhood Hits	69	Target Neighborhood Hits	332	Shared Neighborhood Hits	2
SwissProt Accessions	P42580, Q9JHF2, Q9JKW5, Q9JKW6, Q9JKW9, Q9JKX0, Q9JKX1	Gene names	Nkx1-2, Nkx1.1, Sax1
Domain Architecture
Description	NK1 transcription factor-related protein 2 (Homeobox protein SAX-1) (NKX-1.1).