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Network neighborhood for query Sequence : CERU_MOUSE

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CERU_MOUSE
SwissProt Accessions	Q61147	Gene names	Cp
Domain Architecture
Description	Ceruloplasmin precursor (EC 1.16.3.1) (Ferroxidase).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CERU_HUMAN
θ value	0 (rank : 1)	NC score	0.998657 (rank : 2)
Query Neighborhood Hits	23	Target Neighborhood Hits	15	Shared Neighborhood Hits	9
SwissProt Accessions	P00450, Q14063, Q2PP18, Q9UKS4	Gene names	CP
Domain Architecture
Description	Ceruloplasmin precursor (EC 1.16.3.1) (Ferroxidase).

CERU_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	23	Target Neighborhood Hits	23	Shared Neighborhood Hits	23
SwissProt Accessions	Q61147	Gene names	Cp
Domain Architecture
Description	Ceruloplasmin precursor (EC 1.16.3.1) (Ferroxidase).

HEPH_HUMAN
θ value	0 (rank : 3)	NC score	0.986895 (rank : 4)
Query Neighborhood Hits	23	Target Neighborhood Hits	19	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BQS7, O75180, Q6UW45, Q9C058	Gene names	HEPH, KIAA0698
Domain Architecture	No domain graphic available
Description	Hephaestin precursor (EC 1.-.-.-).

HEPH_MOUSE
θ value	0 (rank : 4)	NC score	0.987103 (rank : 3)
Query Neighborhood Hits	23	Target Neighborhood Hits	17	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Z0Z4, Q6ZQ65, Q80Y80, Q8C4S2	Gene names	Heph, Kiaa0698
Domain Architecture	No domain graphic available
Description	Hephaestin precursor (EC 1.-.-.-).

FA8_HUMAN
θ value	1.02895e-112 (rank : 5)	NC score	0.694526 (rank : 6)
Query Neighborhood Hits	23	Target Neighborhood Hits	112	Shared Neighborhood Hits	7
SwissProt Accessions	P00451	Gene names	F8, F8C
Domain Architecture
Description	Coagulation factor VIII precursor (Procoagulant component) (Antihemophilic factor) (AHF) [Contains: Factor VIIIa heavy chain, 200 kDa isoform; Factor VIIIa heavy chain, 92 kDa isoform; Factor VIII B chain; Factor VIIIa light chain].

FA8_MOUSE
θ value	4.32305e-111 (rank : 6)	NC score	0.695125 (rank : 5)
Query Neighborhood Hits	23	Target Neighborhood Hits	100	Shared Neighborhood Hits	7
SwissProt Accessions	Q06194	Gene names	F8, Cf8, F8c
Domain Architecture
Description	Coagulation factor VIII precursor (Procoagulant component).

FA5_HUMAN
θ value	6.45994e-107 (rank : 7)	NC score	0.669355 (rank : 7)
Query Neighborhood Hits	23	Target Neighborhood Hits	172	Shared Neighborhood Hits	7
SwissProt Accessions	P12259, Q14285, Q6UPU6	Gene names	F5
Domain Architecture
Description	Coagulation factor V precursor (Activated protein C cofactor) [Contains: Coagulation factor V heavy chain; Coagulation factor V light chain].

CP2J6_MOUSE
θ value	1.06291 (rank : 8)	NC score	0.005832 (rank : 47)
Query Neighborhood Hits	23	Target Neighborhood Hits	110	Shared Neighborhood Hits	2
SwissProt Accessions	O54750	Gene names	Cyp2j6
Domain Architecture
Description	Cytochrome P450 2J6 (EC 1.14.14.1) (CYPIIJ6) (Arachidonic acid epoxygenase).

ZNT1_HUMAN
θ value	1.38821 (rank : 9)	NC score	0.031091 (rank : 32)
Query Neighborhood Hits	23	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y6M5, Q9BZF6	Gene names	SLC30A1, ZNT1
Domain Architecture
Description	Zinc transporter 1 (ZnT-1) (Solute carrier family 30 member 1).

CAN11_HUMAN
θ value	1.81305 (rank : 10)	NC score	0.014467 (rank : 37)
Query Neighborhood Hits	23	Target Neighborhood Hits	63	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UMQ6, Q8N4R5	Gene names	CAPN11
Domain Architecture
Description	Calpain-11 (EC 3.4.22.-) (Calcium-activated neutral proteinase 11) (CANP 11).

EGLN1_HUMAN
θ value	3.0926 (rank : 11)	NC score	0.017643 (rank : 34)
Query Neighborhood Hits	23	Target Neighborhood Hits	61	Shared Neighborhood Hits	3
SwissProt Accessions	Q9GZT9, Q8N3M8, Q9BZS8, Q9BZT0	Gene names	EGLN1, C1orf12
Domain Architecture
Description	Egl nine homolog 1 (EC 1.14.11.-) (Hypoxia-inducible factor prolyl hydroxylase 2) (HIF-prolyl hydroxylase 2) (HIF-PH2) (HPH-2) (Prolyl hydroxylase domain-containing protein 2) (PHD2) (SM-20).

EGLN1_MOUSE
θ value	3.0926 (rank : 12)	NC score	0.017411 (rank : 36)
Query Neighborhood Hits	23	Target Neighborhood Hits	88	Shared Neighborhood Hits	3
SwissProt Accessions	Q91YE3, Q8VHJ2, Q922P3	Gene names	Egln1
Domain Architecture
Description	Egl nine homolog 1 (EC 1.14.11.-) (Hypoxia-inducible factor prolyl hydroxylase 2) (HIF-prolyl hydroxylase 2) (HIF-PH2) (HPH-2) (SM-20).

ZNT1_MOUSE
θ value	3.0926 (rank : 13)	NC score	0.027892 (rank : 33)
Query Neighborhood Hits	23	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	Q60738	Gene names	Slc30a1, Znt1
Domain Architecture
Description	Zinc transporter 1 (ZnT-1) (Solute carrier family 30 member 1).

ARY1_MOUSE
θ value	4.03905 (rank : 14)	NC score	0.011843 (rank : 40)
Query Neighborhood Hits	23	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	P50294	Gene names	Nat1, Aac1
Domain Architecture
Description	Arylamine N-acetyltransferase 1 (EC 2.3.1.5) (Arylamide acetylase 1) (N-acetyltransferase type 1) (NAT-1).

PHLD1_HUMAN
θ value	4.03905 (rank : 15)	NC score	0.017447 (rank : 35)
Query Neighborhood Hits	23	Target Neighborhood Hits	48	Shared Neighborhood Hits	4
SwissProt Accessions	P80108, Q15128	Gene names	GPLD1, PIGPLD1
Domain Architecture
Description	Phosphatidylinositol-glycan-specific phospholipase D 1 precursor (EC 3.1.4.50) (PI-G PLD) (Glycoprotein phospholipase D) (Glycosyl- phosphatidylinositol-specific phospholipase D).

IL1F5_MOUSE
θ value	5.27518 (rank : 16)	NC score	0.011863 (rank : 39)
Query Neighborhood Hits	23	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QYY1, Q9JIG2	Gene names	Il1f5, Fil1d, Il1h3, Il1hy1
Domain Architecture
Description	Interleukin-1 family member 5 (IL-1F5) (Interleukin-1 delta) (IL-1 delta) (Interleukin-1-like protein 1) (IL-1L1) (Interleukin-1 HY1) (IL-1HY1) (Interleukin-1 homolog 3) (IL-1H3).

ITPR1_HUMAN
θ value	6.88961 (rank : 17)	NC score	0.008637 (rank : 41)
Query Neighborhood Hits	23	Target Neighborhood Hits	90	Shared Neighborhood Hits	3
SwissProt Accessions	Q14643, Q14660, Q99897	Gene names	ITPR1, INSP3R1
Domain Architecture
Description	Inositol 1,4,5-trisphosphate receptor type 1 (Type 1 inositol 1,4,5- trisphosphate receptor) (Type 1 InsP3 receptor) (IP3 receptor isoform 1) (InsP3R1) (IP3R).

ITPR1_MOUSE
θ value	6.88961 (rank : 18)	NC score	0.008633 (rank : 42)
Query Neighborhood Hits	23	Target Neighborhood Hits	99	Shared Neighborhood Hits	3
SwissProt Accessions	P11881, P20943, Q99LG5	Gene names	Itpr1, Insp3r, Pcd6, Pcp1
Domain Architecture
Description	Inositol 1,4,5-trisphosphate receptor type 1 (Type 1 inositol 1,4,5- trisphosphate receptor) (Type 1 InsP3 receptor) (IP3 receptor isoform 1) (InsP3R1) (Inositol 1,4,5-trisphosphate-binding protein P400) (Purkinje cell protein 1) (Protein PCD-6).

PHLD2_HUMAN
θ value	6.88961 (rank : 19)	NC score	0.012741 (rank : 38)
Query Neighborhood Hits	23	Target Neighborhood Hits	44	Shared Neighborhood Hits	3
SwissProt Accessions	Q15127	Gene names	GPLD2, PIGPLD2
Domain Architecture
Description	Phosphatidylinositol-glycan-specific phospholipase D 2 precursor (EC 3.1.4.50) (PI-G PLD) (Glycoprotein phospholipase D) (Glycosyl- phosphatidylinositol-specific phospholipase D).

CAN7_HUMAN
θ value	8.99809 (rank : 20)	NC score	0.008422 (rank : 43)
Query Neighborhood Hits	23	Target Neighborhood Hits	71	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y6W3	Gene names	CAPN7, PALBH
Domain Architecture
Description	Calpain-7 (EC 3.4.22.-) (PalB homolog) (PalBH).

SMRC1_HUMAN
θ value	8.99809 (rank : 21)	NC score	0.008056 (rank : 44)
Query Neighborhood Hits	23	Target Neighborhood Hits	375	Shared Neighborhood Hits	3
SwissProt Accessions	Q92922, Q6P172, Q8IWH2	Gene names	SMARCC1, BAF155
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1 (SWI/SNF complex 155 kDa subunit) (BRG1-associated factor 155).

SMRC1_MOUSE
θ value	8.99809 (rank : 22)	NC score	0.007859 (rank : 46)
Query Neighborhood Hits	23	Target Neighborhood Hits	459	Shared Neighborhood Hits	3
SwissProt Accessions	P97496, Q7TS80, Q7TT29	Gene names	Smarcc1, Baf155, Srg3
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1 (SWI/SNF complex 155 kDa subunit) (BRG1-associated factor 155) (SWI3-related protein).

THOC2_HUMAN
θ value	8.99809 (rank : 23)	NC score	0.007924 (rank : 45)
Query Neighborhood Hits	23	Target Neighborhood Hits	337	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NI27, Q9H8I6	Gene names	THOC2, CXorf3
Domain Architecture	No domain graphic available
Description	THO complex subunit 2 (Tho2).

CNTP1_HUMAN
θ value	θ > 10 (rank : 24)	NC score	0.063349 (rank : 30)
Query Neighborhood Hits	23	Target Neighborhood Hits	196	Shared Neighborhood Hits	3
SwissProt Accessions	P78357	Gene names	CNTNAP1, CASPR, NRXN4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (p190).

CNTP1_MOUSE
θ value	θ > 10 (rank : 25)	NC score	0.061686 (rank : 31)
Query Neighborhood Hits	23	Target Neighborhood Hits	183	Shared Neighborhood Hits	3
SwissProt Accessions	O54991	Gene names	Cntnap1, Nrxn4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (Paranodin) (NCP1) (MHDNIV).

CNTP2_HUMAN
θ value	θ > 10 (rank : 26)	NC score	0.071695 (rank : 25)
Query Neighborhood Hits	23	Target Neighborhood Hits	199	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UHC6, Q52LV1, Q5H9Q7, Q9UQ12	Gene names	CNTNAP2, CASPR2, KIAA0868
Domain Architecture
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

CNTP2_MOUSE
θ value	θ > 10 (rank : 27)	NC score	0.067696 (rank : 29)
Query Neighborhood Hits	23	Target Neighborhood Hits	194	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CPW0, Q6P2K4, Q6ZQ31	Gene names	Cntnap2, Kiaa0868
Domain Architecture	No domain graphic available
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

CNTP3_HUMAN
θ value	θ > 10 (rank : 28)	NC score	0.068452 (rank : 28)
Query Neighborhood Hits	23	Target Neighborhood Hits	195	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BZ76, Q9C0E9	Gene names	CNTNAP3, CASPR3, KIAA1714
Domain Architecture
Description	Contactin-associated protein-like 3 precursor (Cell recognition molecule Caspr3).

CNTP4_HUMAN
θ value	θ > 10 (rank : 29)	NC score	0.069616 (rank : 27)
Query Neighborhood Hits	23	Target Neighborhood Hits	187	Shared Neighborhood Hits	3
SwissProt Accessions	Q9C0A0	Gene names	CNTNAP4, CASPR4, KIAA1763
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

CNTP4_MOUSE
θ value	θ > 10 (rank : 30)	NC score	0.070068 (rank : 26)
Query Neighborhood Hits	23	Target Neighborhood Hits	193	Shared Neighborhood Hits	3
SwissProt Accessions	Q99P47	Gene names	Cntnap4, Caspr4
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

CPXM1_HUMAN
θ value	θ > 10 (rank : 31)	NC score	0.077628 (rank : 23)
Query Neighborhood Hits	23	Target Neighborhood Hits	69	Shared Neighborhood Hits	3
SwissProt Accessions	Q96SM3, Q6P4G8, Q6UW65, Q9NUB5	Gene names	CPXM1, CPX1, CPXM
Domain Architecture
Description	Probable carboxypeptidase X1 precursor (EC 3.4.17.-) (Metallocarboxypeptidase CPX-1).

CPXM1_MOUSE
θ value	θ > 10 (rank : 32)	NC score	0.077156 (rank : 24)
Query Neighborhood Hits	23	Target Neighborhood Hits	63	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z100, Q99LA3	Gene names	Cpxm1, Cpx1, Cpxm
Domain Architecture
Description	Probable carboxypeptidase X1 precursor (EC 3.4.17.-) (Metallocarboxypeptidase CPX-1).

CPXM2_HUMAN
θ value	θ > 10 (rank : 33)	NC score	0.091480 (rank : 22)
Query Neighborhood Hits	23	Target Neighborhood Hits	84	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N436	Gene names	CPXM2
Domain Architecture
Description	Carboxypeptidase-like protein X2 precursor.

CPXM2_MOUSE
θ value	θ > 10 (rank : 34)	NC score	0.092284 (rank : 21)
Query Neighborhood Hits	23	Target Neighborhood Hits	58	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D2L5, O54860, Q8VDQ4	Gene names	Cpxm2, Cpx2
Domain Architecture
Description	Carboxypeptidase-like protein X2 precursor.

DCBD1_HUMAN
θ value	θ > 10 (rank : 35)	NC score	0.128737 (rank : 14)
Query Neighborhood Hits	23	Target Neighborhood Hits	110	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N8Z6, Q5H992, Q8IYK5, Q8N7L9, Q96NH2	Gene names	DCBLD1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

DCBD2_HUMAN
θ value	θ > 10 (rank : 36)	NC score	0.116361 (rank : 16)
Query Neighborhood Hits	23	Target Neighborhood Hits	118	Shared Neighborhood Hits	3
SwissProt Accessions	Q96PD2, Q8N6M4, Q8TDX2	Gene names	DCBLD2, CLCP1, ESDN
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein) (CUB, LCCL and coagulation factor V/VIII-homology domains protein 1).

DCBD2_MOUSE
θ value	θ > 10 (rank : 37)	NC score	0.117942 (rank : 15)
Query Neighborhood Hits	23	Target Neighborhood Hits	113	Shared Neighborhood Hits	3
SwissProt Accessions	Q91ZV3, Q8BKI4	Gene names	Dcbld2, Esdn
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein).

EDIL3_HUMAN
θ value	θ > 10 (rank : 38)	NC score	0.135407 (rank : 12)
Query Neighborhood Hits	23	Target Neighborhood Hits	292	Shared Neighborhood Hits	3
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

EDIL3_MOUSE
θ value	θ > 10 (rank : 39)	NC score	0.132850 (rank : 13)
Query Neighborhood Hits	23	Target Neighborhood Hits	317	Shared Neighborhood Hits	3
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

MFGM_HUMAN
θ value	θ > 10 (rank : 40)	NC score	0.185042 (rank : 8)
Query Neighborhood Hits	23	Target Neighborhood Hits	150	Shared Neighborhood Hits	3
SwissProt Accessions	Q08431	Gene names	MFGE8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (HMFG) (Breast epithelial antigen BA46) (MFGM) [Contains: Lactadherin short form; Medin].

MFGM_MOUSE
θ value	θ > 10 (rank : 41)	NC score	0.164292 (rank : 9)
Query Neighborhood Hits	23	Target Neighborhood Hits	233	Shared Neighborhood Hits	3
SwissProt Accessions	P21956, P97800, Q3TBN5, Q9R1X9, Q9WTS3	Gene names	Mfge8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (MFGM) (Sperm surface protein SP47) (MP47).

NRP1_HUMAN
θ value	θ > 10 (rank : 42)	NC score	0.105493 (rank : 20)
Query Neighborhood Hits	23	Target Neighborhood Hits	119	Shared Neighborhood Hits	3
SwissProt Accessions	O14786, O60461, Q96IH5	Gene names	NRP1, NRP, VEGF165R
Domain Architecture
Description	Neuropilin-1 precursor (Vascular endothelial cell growth factor 165 receptor) (CD304 antigen).

NRP1_MOUSE
θ value	θ > 10 (rank : 43)	NC score	0.107888 (rank : 19)
Query Neighborhood Hits	23	Target Neighborhood Hits	120	Shared Neighborhood Hits	3
SwissProt Accessions	P97333	Gene names	Nrp1, Nrp
Domain Architecture
Description	Neuropilin-1 precursor (A5 protein).

NRP2_HUMAN
θ value	θ > 10 (rank : 44)	NC score	0.108317 (rank : 18)
Query Neighborhood Hits	23	Target Neighborhood Hits	120	Shared Neighborhood Hits	3
SwissProt Accessions	O60462, O14820, O14821	Gene names	NRP2, VEGF165R2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

NRP2_MOUSE
θ value	θ > 10 (rank : 45)	NC score	0.109308 (rank : 17)
Query Neighborhood Hits	23	Target Neighborhood Hits	113	Shared Neighborhood Hits	3
SwissProt Accessions	O35375, O35373, O35374, O35376, O35377, O35378	Gene names	Nrp2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

XLRS1_HUMAN
θ value	θ > 10 (rank : 46)	NC score	0.152310 (rank : 11)
Query Neighborhood Hits	23	Target Neighborhood Hits	32	Shared Neighborhood Hits	3
SwissProt Accessions	O15537	Gene names	RS1, XLRS1
Domain Architecture
Description	Retinoschisin precursor (X-linked juvenile retinoschisis protein).

XLRS1_MOUSE
θ value	θ > 10 (rank : 47)	NC score	0.152992 (rank : 10)
Query Neighborhood Hits	23	Target Neighborhood Hits	32	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z1L4	Gene names	Rs1, Rs1h, Xlrs1
Domain Architecture
Description	Retinoschisin precursor (X-linked juvenile retinoschisis protein homolog).

Hits sorted by NC score

CERU_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	23	Target Neighborhood Hits	23	Shared Neighborhood Hits	23
SwissProt Accessions	Q61147	Gene names	Cp
Domain Architecture
Description	Ceruloplasmin precursor (EC 1.16.3.1) (Ferroxidase).

CERU_HUMAN
NC score	0.998657 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	23	Target Neighborhood Hits	15	Shared Neighborhood Hits	9
SwissProt Accessions	P00450, Q14063, Q2PP18, Q9UKS4	Gene names	CP
Domain Architecture
Description	Ceruloplasmin precursor (EC 1.16.3.1) (Ferroxidase).

HEPH_MOUSE
NC score	0.987103 (rank : 3)	θ value	0 (rank : 4)
Query Neighborhood Hits	23	Target Neighborhood Hits	17	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Z0Z4, Q6ZQ65, Q80Y80, Q8C4S2	Gene names	Heph, Kiaa0698
Domain Architecture	No domain graphic available
Description	Hephaestin precursor (EC 1.-.-.-).

HEPH_HUMAN
NC score	0.986895 (rank : 4)	θ value	0 (rank : 3)
Query Neighborhood Hits	23	Target Neighborhood Hits	19	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BQS7, O75180, Q6UW45, Q9C058	Gene names	HEPH, KIAA0698
Domain Architecture	No domain graphic available
Description	Hephaestin precursor (EC 1.-.-.-).

FA8_MOUSE
NC score	0.695125 (rank : 5)	θ value	4.32305e-111 (rank : 6)
Query Neighborhood Hits	23	Target Neighborhood Hits	100	Shared Neighborhood Hits	7
SwissProt Accessions	Q06194	Gene names	F8, Cf8, F8c
Domain Architecture
Description	Coagulation factor VIII precursor (Procoagulant component).

FA8_HUMAN
NC score	0.694526 (rank : 6)	θ value	1.02895e-112 (rank : 5)
Query Neighborhood Hits	23	Target Neighborhood Hits	112	Shared Neighborhood Hits	7
SwissProt Accessions	P00451	Gene names	F8, F8C
Domain Architecture
Description	Coagulation factor VIII precursor (Procoagulant component) (Antihemophilic factor) (AHF) [Contains: Factor VIIIa heavy chain, 200 kDa isoform; Factor VIIIa heavy chain, 92 kDa isoform; Factor VIII B chain; Factor VIIIa light chain].

FA5_HUMAN
NC score	0.669355 (rank : 7)	θ value	6.45994e-107 (rank : 7)
Query Neighborhood Hits	23	Target Neighborhood Hits	172	Shared Neighborhood Hits	7
SwissProt Accessions	P12259, Q14285, Q6UPU6	Gene names	F5
Domain Architecture
Description	Coagulation factor V precursor (Activated protein C cofactor) [Contains: Coagulation factor V heavy chain; Coagulation factor V light chain].

MFGM_HUMAN
NC score	0.185042 (rank : 8)	θ value	θ > 10 (rank : 40)
Query Neighborhood Hits	23	Target Neighborhood Hits	150	Shared Neighborhood Hits	3
SwissProt Accessions	Q08431	Gene names	MFGE8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (HMFG) (Breast epithelial antigen BA46) (MFGM) [Contains: Lactadherin short form; Medin].

MFGM_MOUSE
NC score	0.164292 (rank : 9)	θ value	θ > 10 (rank : 41)
Query Neighborhood Hits	23	Target Neighborhood Hits	233	Shared Neighborhood Hits	3
SwissProt Accessions	P21956, P97800, Q3TBN5, Q9R1X9, Q9WTS3	Gene names	Mfge8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (MFGM) (Sperm surface protein SP47) (MP47).

XLRS1_MOUSE
NC score	0.152992 (rank : 10)	θ value	θ > 10 (rank : 47)
Query Neighborhood Hits	23	Target Neighborhood Hits	32	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z1L4	Gene names	Rs1, Rs1h, Xlrs1
Domain Architecture
Description	Retinoschisin precursor (X-linked juvenile retinoschisis protein homolog).

XLRS1_HUMAN
NC score	0.152310 (rank : 11)	θ value	θ > 10 (rank : 46)
Query Neighborhood Hits	23	Target Neighborhood Hits	32	Shared Neighborhood Hits	3
SwissProt Accessions	O15537	Gene names	RS1, XLRS1
Domain Architecture
Description	Retinoschisin precursor (X-linked juvenile retinoschisis protein).

EDIL3_HUMAN
NC score	0.135407 (rank : 12)	θ value	θ > 10 (rank : 38)
Query Neighborhood Hits	23	Target Neighborhood Hits	292	Shared Neighborhood Hits	3
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

EDIL3_MOUSE
NC score	0.132850 (rank : 13)	θ value	θ > 10 (rank : 39)
Query Neighborhood Hits	23	Target Neighborhood Hits	317	Shared Neighborhood Hits	3
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

DCBD1_HUMAN
NC score	0.128737 (rank : 14)	θ value	θ > 10 (rank : 35)
Query Neighborhood Hits	23	Target Neighborhood Hits	110	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N8Z6, Q5H992, Q8IYK5, Q8N7L9, Q96NH2	Gene names	DCBLD1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

DCBD2_MOUSE
NC score	0.117942 (rank : 15)	θ value	θ > 10 (rank : 37)
Query Neighborhood Hits	23	Target Neighborhood Hits	113	Shared Neighborhood Hits	3
SwissProt Accessions	Q91ZV3, Q8BKI4	Gene names	Dcbld2, Esdn
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein).

DCBD2_HUMAN
NC score	0.116361 (rank : 16)	θ value	θ > 10 (rank : 36)
Query Neighborhood Hits	23	Target Neighborhood Hits	118	Shared Neighborhood Hits	3
SwissProt Accessions	Q96PD2, Q8N6M4, Q8TDX2	Gene names	DCBLD2, CLCP1, ESDN
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein) (CUB, LCCL and coagulation factor V/VIII-homology domains protein 1).

NRP2_MOUSE
NC score	0.109308 (rank : 17)	θ value	θ > 10 (rank : 45)
Query Neighborhood Hits	23	Target Neighborhood Hits	113	Shared Neighborhood Hits	3
SwissProt Accessions	O35375, O35373, O35374, O35376, O35377, O35378	Gene names	Nrp2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

NRP2_HUMAN
NC score	0.108317 (rank : 18)	θ value	θ > 10 (rank : 44)
Query Neighborhood Hits	23	Target Neighborhood Hits	120	Shared Neighborhood Hits	3
SwissProt Accessions	O60462, O14820, O14821	Gene names	NRP2, VEGF165R2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

NRP1_MOUSE
NC score	0.107888 (rank : 19)	θ value	θ > 10 (rank : 43)
Query Neighborhood Hits	23	Target Neighborhood Hits	120	Shared Neighborhood Hits	3
SwissProt Accessions	P97333	Gene names	Nrp1, Nrp
Domain Architecture
Description	Neuropilin-1 precursor (A5 protein).

NRP1_HUMAN
NC score	0.105493 (rank : 20)	θ value	θ > 10 (rank : 42)
Query Neighborhood Hits	23	Target Neighborhood Hits	119	Shared Neighborhood Hits	3
SwissProt Accessions	O14786, O60461, Q96IH5	Gene names	NRP1, NRP, VEGF165R
Domain Architecture
Description	Neuropilin-1 precursor (Vascular endothelial cell growth factor 165 receptor) (CD304 antigen).

CPXM2_MOUSE
NC score	0.092284 (rank : 21)	θ value	θ > 10 (rank : 34)
Query Neighborhood Hits	23	Target Neighborhood Hits	58	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D2L5, O54860, Q8VDQ4	Gene names	Cpxm2, Cpx2
Domain Architecture
Description	Carboxypeptidase-like protein X2 precursor.

CPXM2_HUMAN
NC score	0.091480 (rank : 22)	θ value	θ > 10 (rank : 33)
Query Neighborhood Hits	23	Target Neighborhood Hits	84	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N436	Gene names	CPXM2
Domain Architecture
Description	Carboxypeptidase-like protein X2 precursor.

CPXM1_HUMAN
NC score	0.077628 (rank : 23)	θ value	θ > 10 (rank : 31)
Query Neighborhood Hits	23	Target Neighborhood Hits	69	Shared Neighborhood Hits	3
SwissProt Accessions	Q96SM3, Q6P4G8, Q6UW65, Q9NUB5	Gene names	CPXM1, CPX1, CPXM
Domain Architecture
Description	Probable carboxypeptidase X1 precursor (EC 3.4.17.-) (Metallocarboxypeptidase CPX-1).

CPXM1_MOUSE
NC score	0.077156 (rank : 24)	θ value	θ > 10 (rank : 32)
Query Neighborhood Hits	23	Target Neighborhood Hits	63	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z100, Q99LA3	Gene names	Cpxm1, Cpx1, Cpxm
Domain Architecture
Description	Probable carboxypeptidase X1 precursor (EC 3.4.17.-) (Metallocarboxypeptidase CPX-1).

CNTP2_HUMAN
NC score	0.071695 (rank : 25)	θ value	θ > 10 (rank : 26)
Query Neighborhood Hits	23	Target Neighborhood Hits	199	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UHC6, Q52LV1, Q5H9Q7, Q9UQ12	Gene names	CNTNAP2, CASPR2, KIAA0868
Domain Architecture
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

CNTP4_MOUSE
NC score	0.070068 (rank : 26)	θ value	θ > 10 (rank : 30)
Query Neighborhood Hits	23	Target Neighborhood Hits	193	Shared Neighborhood Hits	3
SwissProt Accessions	Q99P47	Gene names	Cntnap4, Caspr4
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

CNTP4_HUMAN
NC score	0.069616 (rank : 27)	θ value	θ > 10 (rank : 29)
Query Neighborhood Hits	23	Target Neighborhood Hits	187	Shared Neighborhood Hits	3
SwissProt Accessions	Q9C0A0	Gene names	CNTNAP4, CASPR4, KIAA1763
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

CNTP3_HUMAN
NC score	0.068452 (rank : 28)	θ value	θ > 10 (rank : 28)
Query Neighborhood Hits	23	Target Neighborhood Hits	195	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BZ76, Q9C0E9	Gene names	CNTNAP3, CASPR3, KIAA1714
Domain Architecture
Description	Contactin-associated protein-like 3 precursor (Cell recognition molecule Caspr3).

CNTP2_MOUSE
NC score	0.067696 (rank : 29)	θ value	θ > 10 (rank : 27)
Query Neighborhood Hits	23	Target Neighborhood Hits	194	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CPW0, Q6P2K4, Q6ZQ31	Gene names	Cntnap2, Kiaa0868
Domain Architecture	No domain graphic available
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

CNTP1_HUMAN
NC score	0.063349 (rank : 30)	θ value	θ > 10 (rank : 24)
Query Neighborhood Hits	23	Target Neighborhood Hits	196	Shared Neighborhood Hits	3
SwissProt Accessions	P78357	Gene names	CNTNAP1, CASPR, NRXN4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (p190).

CNTP1_MOUSE
NC score	0.061686 (rank : 31)	θ value	θ > 10 (rank : 25)
Query Neighborhood Hits	23	Target Neighborhood Hits	183	Shared Neighborhood Hits	3
SwissProt Accessions	O54991	Gene names	Cntnap1, Nrxn4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (Paranodin) (NCP1) (MHDNIV).

ZNT1_HUMAN
NC score	0.031091 (rank : 32)	θ value	1.38821 (rank : 9)
Query Neighborhood Hits	23	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y6M5, Q9BZF6	Gene names	SLC30A1, ZNT1
Domain Architecture
Description	Zinc transporter 1 (ZnT-1) (Solute carrier family 30 member 1).

ZNT1_MOUSE
NC score	0.027892 (rank : 33)	θ value	3.0926 (rank : 13)
Query Neighborhood Hits	23	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	Q60738	Gene names	Slc30a1, Znt1
Domain Architecture
Description	Zinc transporter 1 (ZnT-1) (Solute carrier family 30 member 1).

EGLN1_HUMAN
NC score	0.017643 (rank : 34)	θ value	3.0926 (rank : 11)
Query Neighborhood Hits	23	Target Neighborhood Hits	61	Shared Neighborhood Hits	3
SwissProt Accessions	Q9GZT9, Q8N3M8, Q9BZS8, Q9BZT0	Gene names	EGLN1, C1orf12
Domain Architecture
Description	Egl nine homolog 1 (EC 1.14.11.-) (Hypoxia-inducible factor prolyl hydroxylase 2) (HIF-prolyl hydroxylase 2) (HIF-PH2) (HPH-2) (Prolyl hydroxylase domain-containing protein 2) (PHD2) (SM-20).

PHLD1_HUMAN
NC score	0.017447 (rank : 35)	θ value	4.03905 (rank : 15)
Query Neighborhood Hits	23	Target Neighborhood Hits	48	Shared Neighborhood Hits	4
SwissProt Accessions	P80108, Q15128	Gene names	GPLD1, PIGPLD1
Domain Architecture
Description	Phosphatidylinositol-glycan-specific phospholipase D 1 precursor (EC 3.1.4.50) (PI-G PLD) (Glycoprotein phospholipase D) (Glycosyl- phosphatidylinositol-specific phospholipase D).

EGLN1_MOUSE
NC score	0.017411 (rank : 36)	θ value	3.0926 (rank : 12)
Query Neighborhood Hits	23	Target Neighborhood Hits	88	Shared Neighborhood Hits	3
SwissProt Accessions	Q91YE3, Q8VHJ2, Q922P3	Gene names	Egln1
Domain Architecture
Description	Egl nine homolog 1 (EC 1.14.11.-) (Hypoxia-inducible factor prolyl hydroxylase 2) (HIF-prolyl hydroxylase 2) (HIF-PH2) (HPH-2) (SM-20).

CAN11_HUMAN
NC score	0.014467 (rank : 37)	θ value	1.81305 (rank : 10)
Query Neighborhood Hits	23	Target Neighborhood Hits	63	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UMQ6, Q8N4R5	Gene names	CAPN11
Domain Architecture
Description	Calpain-11 (EC 3.4.22.-) (Calcium-activated neutral proteinase 11) (CANP 11).

PHLD2_HUMAN
NC score	0.012741 (rank : 38)	θ value	6.88961 (rank : 19)
Query Neighborhood Hits	23	Target Neighborhood Hits	44	Shared Neighborhood Hits	3
SwissProt Accessions	Q15127	Gene names	GPLD2, PIGPLD2
Domain Architecture
Description	Phosphatidylinositol-glycan-specific phospholipase D 2 precursor (EC 3.1.4.50) (PI-G PLD) (Glycoprotein phospholipase D) (Glycosyl- phosphatidylinositol-specific phospholipase D).

IL1F5_MOUSE
NC score	0.011863 (rank : 39)	θ value	5.27518 (rank : 16)
Query Neighborhood Hits	23	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QYY1, Q9JIG2	Gene names	Il1f5, Fil1d, Il1h3, Il1hy1
Domain Architecture
Description	Interleukin-1 family member 5 (IL-1F5) (Interleukin-1 delta) (IL-1 delta) (Interleukin-1-like protein 1) (IL-1L1) (Interleukin-1 HY1) (IL-1HY1) (Interleukin-1 homolog 3) (IL-1H3).

ARY1_MOUSE
NC score	0.011843 (rank : 40)	θ value	4.03905 (rank : 14)
Query Neighborhood Hits	23	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	P50294	Gene names	Nat1, Aac1
Domain Architecture
Description	Arylamine N-acetyltransferase 1 (EC 2.3.1.5) (Arylamide acetylase 1) (N-acetyltransferase type 1) (NAT-1).

ITPR1_HUMAN
NC score	0.008637 (rank : 41)	θ value	6.88961 (rank : 17)
Query Neighborhood Hits	23	Target Neighborhood Hits	90	Shared Neighborhood Hits	3
SwissProt Accessions	Q14643, Q14660, Q99897	Gene names	ITPR1, INSP3R1
Domain Architecture
Description	Inositol 1,4,5-trisphosphate receptor type 1 (Type 1 inositol 1,4,5- trisphosphate receptor) (Type 1 InsP3 receptor) (IP3 receptor isoform 1) (InsP3R1) (IP3R).

ITPR1_MOUSE
NC score	0.008633 (rank : 42)	θ value	6.88961 (rank : 18)
Query Neighborhood Hits	23	Target Neighborhood Hits	99	Shared Neighborhood Hits	3
SwissProt Accessions	P11881, P20943, Q99LG5	Gene names	Itpr1, Insp3r, Pcd6, Pcp1
Domain Architecture
Description	Inositol 1,4,5-trisphosphate receptor type 1 (Type 1 inositol 1,4,5- trisphosphate receptor) (Type 1 InsP3 receptor) (IP3 receptor isoform 1) (InsP3R1) (Inositol 1,4,5-trisphosphate-binding protein P400) (Purkinje cell protein 1) (Protein PCD-6).

CAN7_HUMAN
NC score	0.008422 (rank : 43)	θ value	8.99809 (rank : 20)
Query Neighborhood Hits	23	Target Neighborhood Hits	71	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y6W3	Gene names	CAPN7, PALBH
Domain Architecture
Description	Calpain-7 (EC 3.4.22.-) (PalB homolog) (PalBH).

SMRC1_HUMAN
NC score	0.008056 (rank : 44)	θ value	8.99809 (rank : 21)
Query Neighborhood Hits	23	Target Neighborhood Hits	375	Shared Neighborhood Hits	3
SwissProt Accessions	Q92922, Q6P172, Q8IWH2	Gene names	SMARCC1, BAF155
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1 (SWI/SNF complex 155 kDa subunit) (BRG1-associated factor 155).

THOC2_HUMAN
NC score	0.007924 (rank : 45)	θ value	8.99809 (rank : 23)
Query Neighborhood Hits	23	Target Neighborhood Hits	337	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NI27, Q9H8I6	Gene names	THOC2, CXorf3
Domain Architecture	No domain graphic available
Description	THO complex subunit 2 (Tho2).

SMRC1_MOUSE
NC score	0.007859 (rank : 46)	θ value	8.99809 (rank : 22)
Query Neighborhood Hits	23	Target Neighborhood Hits	459	Shared Neighborhood Hits	3
SwissProt Accessions	P97496, Q7TS80, Q7TT29	Gene names	Smarcc1, Baf155, Srg3
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1 (SWI/SNF complex 155 kDa subunit) (BRG1-associated factor 155) (SWI3-related protein).

CP2J6_MOUSE
NC score	0.005832 (rank : 47)	θ value	1.06291 (rank : 8)
Query Neighborhood Hits	23	Target Neighborhood Hits	110	Shared Neighborhood Hits	2
SwissProt Accessions	O54750	Gene names	Cyp2j6
Domain Architecture
Description	Cytochrome P450 2J6 (EC 1.14.14.1) (CYPIIJ6) (Arachidonic acid epoxygenase).