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Network neighborhood for query Sequence : PI51C_MOUSE

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PI51C_MOUSE
SwissProt Accessions	O70161, Q505A1, Q80TW9, Q8VCU5	Gene names	Pip5k1c, Kiaa0589
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type I gamma) (PtdIns(4)P- 5-kinase gamma) (PtdInsPKIgamma) (PIP5KIgamma).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PI51A_HUMAN
θ value	0 (rank : 1)	NC score	0.992354 (rank : 3)
Query Neighborhood Hits	25	Target Neighborhood Hits	22	Shared Neighborhood Hits	13
SwissProt Accessions	Q99755, Q99754, Q99756	Gene names	PIP5K1A
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 5-kinase type-1 alpha (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type I alpha) (PtdIns(4)P- 5-kinase alpha) (PIP5KIalpha) (68 kDa type I phosphatidylinositol-4- phosphate 5-kinase alpha).

PI51A_MOUSE
θ value	0 (rank : 2)	NC score	0.993908 (rank : 2)
Query Neighborhood Hits	25	Target Neighborhood Hits	21	Shared Neighborhood Hits	14
SwissProt Accessions	P70182, Q8K0D3, Q99L80	Gene names	Pip5k1a, Pip5k1b
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 5-kinase type-1 alpha (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type I alpha) (PtdIns(4)P- 5-kinase alpha) (PIP5KIalpha) (Phosphatidylinositol-4-phosphate 5- kinase type I beta) (PI4P5KIbeta) (68 kDa type I phosphatidylinositol- 4-phosphate 5-kinase).

PI51C_HUMAN
θ value	0 (rank : 3)	NC score	0.989471 (rank : 6)
Query Neighborhood Hits	25	Target Neighborhood Hits	109	Shared Neighborhood Hits	22
SwissProt Accessions	O60331, Q7LE07	Gene names	PIP5K1C, KIAA0589
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type I gamma) (PtdIns(4)P- 5-kinase gamma) (PtdInsPKIgamma) (PIP5KIgamma).

PI51C_MOUSE
θ value	0 (rank : 4)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	25	Target Neighborhood Hits	25	Shared Neighborhood Hits	25
SwissProt Accessions	O70161, Q505A1, Q80TW9, Q8VCU5	Gene names	Pip5k1c, Kiaa0589
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type I gamma) (PtdIns(4)P- 5-kinase gamma) (PtdInsPKIgamma) (PIP5KIgamma).

PI51B_MOUSE
θ value	8.53067e-184 (rank : 5)	NC score	0.991592 (rank : 4)
Query Neighborhood Hits	25	Target Neighborhood Hits	15	Shared Neighborhood Hits	12
SwissProt Accessions	P70181, O70335, Q8JZY6	Gene names	Pip5k1b, Pip5k1a
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 5-kinase type-1 beta (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type I beta) (PtdIns(4)P-5- kinase beta) (PIP5KIbeta) (Phosphatidylinositol-4-phosphate 5-kinase type I alpha) (PIP5KIalpha).

PI51B_HUMAN
θ value	3.47146e-177 (rank : 6)	NC score	0.991549 (rank : 5)
Query Neighborhood Hits	25	Target Neighborhood Hits	17	Shared Neighborhood Hits	12
SwissProt Accessions	O14986, P78518, P78519, Q5T5K6, Q5T5K8, Q5T5K9, Q5VZ00, Q7KYT5, Q8NHQ5, Q92749	Gene names	PIP5K1B, STM7
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 5-kinase type-1 beta (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type I beta) (PtdIns(4)P-5- kinase beta) (PIP5KIbeta) (Type I phosphatidylinositol-4-phosphate 5- kinase beta) (Protein STM-7).

PI52B_HUMAN
θ value	1.12514e-34 (rank : 7)	NC score	0.826651 (rank : 8)
Query Neighborhood Hits	25	Target Neighborhood Hits	23	Shared Neighborhood Hits	12
SwissProt Accessions	P78356, Q5U0E8, Q8TBP2	Gene names	PIP5K2B
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 5-kinase type-2 beta (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type II beta) (1- phosphatidylinositol-4-phosphate 5-kinase 2-beta) (PtdIns(4)P-5-kinase isoform 2-beta) (PIP5KII-beta) (Diphosphoinositide kinase 2-beta).

PI52B_MOUSE
θ value	1.12514e-34 (rank : 8)	NC score	0.827006 (rank : 7)
Query Neighborhood Hits	25	Target Neighborhood Hits	20	Shared Neighborhood Hits	12
SwissProt Accessions	Q80XI4, Q8VHB2	Gene names	Pip5k2b
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 5-kinase type-2 beta (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type II beta) (1- phosphatidylinositol-4-phosphate 5-kinase 2-beta) (PtdIns(4)P-5-kinase isoform 2-beta) (PIP5KII-beta) (Diphosphoinositide kinase 2-beta).

PI52A_HUMAN
θ value	4.00176e-32 (rank : 9)	NC score	0.818760 (rank : 9)
Query Neighborhood Hits	25	Target Neighborhood Hits	17	Shared Neighborhood Hits	12
SwissProt Accessions	P48426, P53807, Q5VUX3	Gene names	PIP5K2A, PIP5K2
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 5-kinase type-2 alpha (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type II alpha) (1- phosphatidylinositol-4-phosphate 5-kinase 2-alpha) (PtdIns(4)P-5- kinase isoform 2-alpha) (PIP5KII-alpha) (Diphosphoinositide kinase 2- alpha) (PtdIns(4)P-5-kinase B isoform) (PIP5KIII) (PtdIns(4)P-5-kinase C isoform).

PI52A_MOUSE
θ value	6.82597e-32 (rank : 10)	NC score	0.816794 (rank : 10)
Query Neighborhood Hits	25	Target Neighborhood Hits	16	Shared Neighborhood Hits	12
SwissProt Accessions	O70172	Gene names	Pip5k2a
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 5-kinase type-2 alpha (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type II alpha) (1- phosphatidylinositol-4-phosphate 5-kinase 2-alpha) (PtdIns(4)P-5- kinase isoform 2-alpha) (PIP5KII-alpha) (Diphosphoinositide kinase 2- alpha).

FYV1_MOUSE
θ value	1.06045e-08 (rank : 11)	NC score	0.331238 (rank : 11)
Query Neighborhood Hits	25	Target Neighborhood Hits	191	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Z1T6	Gene names	Pip5k3, Pikfyve
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (PIP5K) (PtdIns(4)P-5- kinase) (PIKfyve) (p235).

FYV1_HUMAN
θ value	2.36244e-08 (rank : 12)	NC score	0.319890 (rank : 12)
Query Neighborhood Hits	25	Target Neighborhood Hits	217	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y2I7, Q8NB67	Gene names	PIP5K3, KIAA0981, PIKFYVE
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (Phosphatidylinositol-3- phosphate 5-kinase type III) (PIP5K) (PtdIns(4)P-5-kinase) (PIKfyve) (p235).

RFIP1_HUMAN
θ value	0.0113563 (rank : 13)	NC score	0.052142 (rank : 13)
Query Neighborhood Hits	25	Target Neighborhood Hits	236	Shared Neighborhood Hits	4
SwissProt Accessions	Q6WKZ4, Q6AZK4, Q6WKZ2, Q6WKZ6, Q86YV4, Q8TDL1, Q9H642	Gene names	RAB11FIP1, RCP
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

WNK2_HUMAN
θ value	0.279714 (rank : 14)	NC score	0.006388 (rank : 23)
Query Neighborhood Hits	25	Target Neighborhood Hits	1407	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

MAON_HUMAN
θ value	3.0926 (rank : 15)	NC score	0.010315 (rank : 21)
Query Neighborhood Hits	25	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	Q16798	Gene names	ME3
Domain Architecture
Description	NADP-dependent malic enzyme, mitochondrial precursor (EC 1.1.1.40) (NADP-ME) (Malic enzyme 3).

ADDB_MOUSE
θ value	4.03905 (rank : 16)	NC score	0.013909 (rank : 17)
Query Neighborhood Hits	25	Target Neighborhood Hits	574	Shared Neighborhood Hits	5
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

FA8_HUMAN
θ value	4.03905 (rank : 17)	NC score	0.016595 (rank : 16)
Query Neighborhood Hits	25	Target Neighborhood Hits	112	Shared Neighborhood Hits	5
SwissProt Accessions	P00451	Gene names	F8, F8C
Domain Architecture
Description	Coagulation factor VIII precursor (Procoagulant component) (Antihemophilic factor) (AHF) [Contains: Factor VIIIa heavy chain, 200 kDa isoform; Factor VIIIa heavy chain, 92 kDa isoform; Factor VIII B chain; Factor VIIIa light chain].

RFFL_HUMAN
θ value	4.03905 (rank : 18)	NC score	0.022023 (rank : 14)
Query Neighborhood Hits	25	Target Neighborhood Hits	175	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WZ73, Q8NHW0, Q8TBY7, Q96BE6	Gene names	RFFL, RNF189, RNF34L
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (FYVE-RING finger protein Sakura) (Fring) (Caspases-8 and -10- associated RING finger protein 2) (CARP-2) (Caspase regulator CARP2) (RING finger protein 189) (RING finger protein 34-like).

PDZD2_HUMAN
θ value	5.27518 (rank : 19)	NC score	0.005194 (rank : 24)
Query Neighborhood Hits	25	Target Neighborhood Hits	772	Shared Neighborhood Hits	3
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

HEXB_MOUSE
θ value	6.88961 (rank : 20)	NC score	0.017941 (rank : 15)
Query Neighborhood Hits	25	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	P20060	Gene names	Hexb
Domain Architecture
Description	Beta-hexosaminidase beta chain precursor (EC 3.2.1.52) (N-acetyl-beta- glucosaminidase) (Beta-N-acetylhexosaminidase) (Hexosaminidase B).

NVL_HUMAN
θ value	6.88961 (rank : 21)	NC score	0.006453 (rank : 22)
Query Neighborhood Hits	25	Target Neighborhood Hits	112	Shared Neighborhood Hits	3
SwissProt Accessions	O15381, Q96EM7	Gene names	NVL
Domain Architecture
Description	Nuclear valosin-containing protein-like (Nuclear VCP-like protein) (NVLp).

BIR1E_MOUSE
θ value	8.99809 (rank : 22)	NC score	0.011147 (rank : 20)
Query Neighborhood Hits	25	Target Neighborhood Hits	93	Shared Neighborhood Hits	5
SwissProt Accessions	Q9R016, O09121, O09122, P81703, Q9R029	Gene names	Birc1e, Naip-rs3, Naip5
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1e (Neuronal apoptosis inhibitory protein 5).

BIR1F_MOUSE
θ value	8.99809 (rank : 23)	NC score	0.011157 (rank : 19)
Query Neighborhood Hits	25	Target Neighborhood Hits	88	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JIB6, O09121, O09122, P81704	Gene names	Birc1f, Naip-rs4, Naip6
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1f (Neuronal apoptosis inhibitory protein 6).

BIR1G_MOUSE
θ value	8.99809 (rank : 24)	NC score	0.011596 (rank : 18)
Query Neighborhood Hits	25	Target Neighborhood Hits	92	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JIB3	Gene names	Birc1g, Naip7
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1g (Neuronal apoptosis inhibitory protein 7).

FOG2_MOUSE
θ value	8.99809 (rank : 25)	NC score	0.000962 (rank : 25)
Query Neighborhood Hits	25	Target Neighborhood Hits	714	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CCH7, Q9Z0F2	Gene names	Zfpm2, Fog2
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM2 (Zinc finger protein multitype 2) (Friend of GATA protein 2) (Friend of GATA-2) (FOG-2) (mFOG-2).

Hits sorted by NC score

PI51C_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 4)
Query Neighborhood Hits	25	Target Neighborhood Hits	25	Shared Neighborhood Hits	25
SwissProt Accessions	O70161, Q505A1, Q80TW9, Q8VCU5	Gene names	Pip5k1c, Kiaa0589
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type I gamma) (PtdIns(4)P- 5-kinase gamma) (PtdInsPKIgamma) (PIP5KIgamma).

PI51A_MOUSE
NC score	0.993908 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	25	Target Neighborhood Hits	21	Shared Neighborhood Hits	14
SwissProt Accessions	P70182, Q8K0D3, Q99L80	Gene names	Pip5k1a, Pip5k1b
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 5-kinase type-1 alpha (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type I alpha) (PtdIns(4)P- 5-kinase alpha) (PIP5KIalpha) (Phosphatidylinositol-4-phosphate 5- kinase type I beta) (PI4P5KIbeta) (68 kDa type I phosphatidylinositol- 4-phosphate 5-kinase).

PI51A_HUMAN
NC score	0.992354 (rank : 3)	θ value	0 (rank : 1)
Query Neighborhood Hits	25	Target Neighborhood Hits	22	Shared Neighborhood Hits	13
SwissProt Accessions	Q99755, Q99754, Q99756	Gene names	PIP5K1A
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 5-kinase type-1 alpha (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type I alpha) (PtdIns(4)P- 5-kinase alpha) (PIP5KIalpha) (68 kDa type I phosphatidylinositol-4- phosphate 5-kinase alpha).

PI51B_MOUSE
NC score	0.991592 (rank : 4)	θ value	8.53067e-184 (rank : 5)
Query Neighborhood Hits	25	Target Neighborhood Hits	15	Shared Neighborhood Hits	12
SwissProt Accessions	P70181, O70335, Q8JZY6	Gene names	Pip5k1b, Pip5k1a
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 5-kinase type-1 beta (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type I beta) (PtdIns(4)P-5- kinase beta) (PIP5KIbeta) (Phosphatidylinositol-4-phosphate 5-kinase type I alpha) (PIP5KIalpha).

PI51B_HUMAN
NC score	0.991549 (rank : 5)	θ value	3.47146e-177 (rank : 6)
Query Neighborhood Hits	25	Target Neighborhood Hits	17	Shared Neighborhood Hits	12
SwissProt Accessions	O14986, P78518, P78519, Q5T5K6, Q5T5K8, Q5T5K9, Q5VZ00, Q7KYT5, Q8NHQ5, Q92749	Gene names	PIP5K1B, STM7
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 5-kinase type-1 beta (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type I beta) (PtdIns(4)P-5- kinase beta) (PIP5KIbeta) (Type I phosphatidylinositol-4-phosphate 5- kinase beta) (Protein STM-7).

PI51C_HUMAN
NC score	0.989471 (rank : 6)	θ value	0 (rank : 3)
Query Neighborhood Hits	25	Target Neighborhood Hits	109	Shared Neighborhood Hits	22
SwissProt Accessions	O60331, Q7LE07	Gene names	PIP5K1C, KIAA0589
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type I gamma) (PtdIns(4)P- 5-kinase gamma) (PtdInsPKIgamma) (PIP5KIgamma).

PI52B_MOUSE
NC score	0.827006 (rank : 7)	θ value	1.12514e-34 (rank : 8)
Query Neighborhood Hits	25	Target Neighborhood Hits	20	Shared Neighborhood Hits	12
SwissProt Accessions	Q80XI4, Q8VHB2	Gene names	Pip5k2b
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 5-kinase type-2 beta (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type II beta) (1- phosphatidylinositol-4-phosphate 5-kinase 2-beta) (PtdIns(4)P-5-kinase isoform 2-beta) (PIP5KII-beta) (Diphosphoinositide kinase 2-beta).

PI52B_HUMAN
NC score	0.826651 (rank : 8)	θ value	1.12514e-34 (rank : 7)
Query Neighborhood Hits	25	Target Neighborhood Hits	23	Shared Neighborhood Hits	12
SwissProt Accessions	P78356, Q5U0E8, Q8TBP2	Gene names	PIP5K2B
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 5-kinase type-2 beta (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type II beta) (1- phosphatidylinositol-4-phosphate 5-kinase 2-beta) (PtdIns(4)P-5-kinase isoform 2-beta) (PIP5KII-beta) (Diphosphoinositide kinase 2-beta).

PI52A_HUMAN
NC score	0.818760 (rank : 9)	θ value	4.00176e-32 (rank : 9)
Query Neighborhood Hits	25	Target Neighborhood Hits	17	Shared Neighborhood Hits	12
SwissProt Accessions	P48426, P53807, Q5VUX3	Gene names	PIP5K2A, PIP5K2
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 5-kinase type-2 alpha (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type II alpha) (1- phosphatidylinositol-4-phosphate 5-kinase 2-alpha) (PtdIns(4)P-5- kinase isoform 2-alpha) (PIP5KII-alpha) (Diphosphoinositide kinase 2- alpha) (PtdIns(4)P-5-kinase B isoform) (PIP5KIII) (PtdIns(4)P-5-kinase C isoform).

PI52A_MOUSE
NC score	0.816794 (rank : 10)	θ value	6.82597e-32 (rank : 10)
Query Neighborhood Hits	25	Target Neighborhood Hits	16	Shared Neighborhood Hits	12
SwissProt Accessions	O70172	Gene names	Pip5k2a
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 5-kinase type-2 alpha (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type II alpha) (1- phosphatidylinositol-4-phosphate 5-kinase 2-alpha) (PtdIns(4)P-5- kinase isoform 2-alpha) (PIP5KII-alpha) (Diphosphoinositide kinase 2- alpha).

FYV1_MOUSE
NC score	0.331238 (rank : 11)	θ value	1.06045e-08 (rank : 11)
Query Neighborhood Hits	25	Target Neighborhood Hits	191	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Z1T6	Gene names	Pip5k3, Pikfyve
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (PIP5K) (PtdIns(4)P-5- kinase) (PIKfyve) (p235).

FYV1_HUMAN
NC score	0.319890 (rank : 12)	θ value	2.36244e-08 (rank : 12)
Query Neighborhood Hits	25	Target Neighborhood Hits	217	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y2I7, Q8NB67	Gene names	PIP5K3, KIAA0981, PIKFYVE
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (Phosphatidylinositol-3- phosphate 5-kinase type III) (PIP5K) (PtdIns(4)P-5-kinase) (PIKfyve) (p235).

RFIP1_HUMAN
NC score	0.052142 (rank : 13)	θ value	0.0113563 (rank : 13)
Query Neighborhood Hits	25	Target Neighborhood Hits	236	Shared Neighborhood Hits	4
SwissProt Accessions	Q6WKZ4, Q6AZK4, Q6WKZ2, Q6WKZ6, Q86YV4, Q8TDL1, Q9H642	Gene names	RAB11FIP1, RCP
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

RFFL_HUMAN
NC score	0.022023 (rank : 14)	θ value	4.03905 (rank : 18)
Query Neighborhood Hits	25	Target Neighborhood Hits	175	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WZ73, Q8NHW0, Q8TBY7, Q96BE6	Gene names	RFFL, RNF189, RNF34L
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (FYVE-RING finger protein Sakura) (Fring) (Caspases-8 and -10- associated RING finger protein 2) (CARP-2) (Caspase regulator CARP2) (RING finger protein 189) (RING finger protein 34-like).

HEXB_MOUSE
NC score	0.017941 (rank : 15)	θ value	6.88961 (rank : 20)
Query Neighborhood Hits	25	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	P20060	Gene names	Hexb
Domain Architecture
Description	Beta-hexosaminidase beta chain precursor (EC 3.2.1.52) (N-acetyl-beta- glucosaminidase) (Beta-N-acetylhexosaminidase) (Hexosaminidase B).

FA8_HUMAN
NC score	0.016595 (rank : 16)	θ value	4.03905 (rank : 17)
Query Neighborhood Hits	25	Target Neighborhood Hits	112	Shared Neighborhood Hits	5
SwissProt Accessions	P00451	Gene names	F8, F8C
Domain Architecture
Description	Coagulation factor VIII precursor (Procoagulant component) (Antihemophilic factor) (AHF) [Contains: Factor VIIIa heavy chain, 200 kDa isoform; Factor VIIIa heavy chain, 92 kDa isoform; Factor VIII B chain; Factor VIIIa light chain].

ADDB_MOUSE
NC score	0.013909 (rank : 17)	θ value	4.03905 (rank : 16)
Query Neighborhood Hits	25	Target Neighborhood Hits	574	Shared Neighborhood Hits	5
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

BIR1G_MOUSE
NC score	0.011596 (rank : 18)	θ value	8.99809 (rank : 24)
Query Neighborhood Hits	25	Target Neighborhood Hits	92	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JIB3	Gene names	Birc1g, Naip7
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1g (Neuronal apoptosis inhibitory protein 7).

BIR1F_MOUSE
NC score	0.011157 (rank : 19)	θ value	8.99809 (rank : 23)
Query Neighborhood Hits	25	Target Neighborhood Hits	88	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JIB6, O09121, O09122, P81704	Gene names	Birc1f, Naip-rs4, Naip6
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1f (Neuronal apoptosis inhibitory protein 6).

BIR1E_MOUSE
NC score	0.011147 (rank : 20)	θ value	8.99809 (rank : 22)
Query Neighborhood Hits	25	Target Neighborhood Hits	93	Shared Neighborhood Hits	5
SwissProt Accessions	Q9R016, O09121, O09122, P81703, Q9R029	Gene names	Birc1e, Naip-rs3, Naip5
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1e (Neuronal apoptosis inhibitory protein 5).

MAON_HUMAN
NC score	0.010315 (rank : 21)	θ value	3.0926 (rank : 15)
Query Neighborhood Hits	25	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	Q16798	Gene names	ME3
Domain Architecture
Description	NADP-dependent malic enzyme, mitochondrial precursor (EC 1.1.1.40) (NADP-ME) (Malic enzyme 3).

NVL_HUMAN
NC score	0.006453 (rank : 22)	θ value	6.88961 (rank : 21)
Query Neighborhood Hits	25	Target Neighborhood Hits	112	Shared Neighborhood Hits	3
SwissProt Accessions	O15381, Q96EM7	Gene names	NVL
Domain Architecture
Description	Nuclear valosin-containing protein-like (Nuclear VCP-like protein) (NVLp).

WNK2_HUMAN
NC score	0.006388 (rank : 23)	θ value	0.279714 (rank : 14)
Query Neighborhood Hits	25	Target Neighborhood Hits	1407	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

PDZD2_HUMAN
NC score	0.005194 (rank : 24)	θ value	5.27518 (rank : 19)
Query Neighborhood Hits	25	Target Neighborhood Hits	772	Shared Neighborhood Hits	3
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

FOG2_MOUSE
NC score	0.000962 (rank : 25)	θ value	8.99809 (rank : 25)
Query Neighborhood Hits	25	Target Neighborhood Hits	714	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CCH7, Q9Z0F2	Gene names	Zfpm2, Fog2
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM2 (Zinc finger protein multitype 2) (Friend of GATA protein 2) (Friend of GATA-2) (FOG-2) (mFOG-2).