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Network neighborhood for query Sequence : PI52A_MOUSE

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PI52A_MOUSE
SwissProt Accessions	O70172	Gene names	Pip5k2a
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 5-kinase type-2 alpha (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type II alpha) (1- phosphatidylinositol-4-phosphate 5-kinase 2-alpha) (PtdIns(4)P-5- kinase isoform 2-alpha) (PIP5KII-alpha) (Diphosphoinositide kinase 2- alpha).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PI52A_HUMAN
θ value	0 (rank : 1)	NC score	0.999782 (rank : 2)
Query Neighborhood Hits	16	Target Neighborhood Hits	17	Shared Neighborhood Hits	15
SwissProt Accessions	P48426, P53807, Q5VUX3	Gene names	PIP5K2A, PIP5K2
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 5-kinase type-2 alpha (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type II alpha) (1- phosphatidylinositol-4-phosphate 5-kinase 2-alpha) (PtdIns(4)P-5- kinase isoform 2-alpha) (PIP5KII-alpha) (Diphosphoinositide kinase 2- alpha) (PtdIns(4)P-5-kinase B isoform) (PIP5KIII) (PtdIns(4)P-5-kinase C isoform).

PI52A_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	16	Target Neighborhood Hits	16	Shared Neighborhood Hits	16
SwissProt Accessions	O70172	Gene names	Pip5k2a
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 5-kinase type-2 alpha (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type II alpha) (1- phosphatidylinositol-4-phosphate 5-kinase 2-alpha) (PtdIns(4)P-5- kinase isoform 2-alpha) (PIP5KII-alpha) (Diphosphoinositide kinase 2- alpha).

PI52B_MOUSE
θ value	2.33393e-165 (rank : 3)	NC score	0.996180 (rank : 3)
Query Neighborhood Hits	16	Target Neighborhood Hits	20	Shared Neighborhood Hits	13
SwissProt Accessions	Q80XI4, Q8VHB2	Gene names	Pip5k2b
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 5-kinase type-2 beta (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type II beta) (1- phosphatidylinositol-4-phosphate 5-kinase 2-beta) (PtdIns(4)P-5-kinase isoform 2-beta) (PIP5KII-beta) (Diphosphoinositide kinase 2-beta).

PI52B_HUMAN
θ value	5.19945e-165 (rank : 4)	NC score	0.995815 (rank : 4)
Query Neighborhood Hits	16	Target Neighborhood Hits	23	Shared Neighborhood Hits	13
SwissProt Accessions	P78356, Q5U0E8, Q8TBP2	Gene names	PIP5K2B
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 5-kinase type-2 beta (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type II beta) (1- phosphatidylinositol-4-phosphate 5-kinase 2-beta) (PtdIns(4)P-5-kinase isoform 2-beta) (PIP5KII-beta) (Diphosphoinositide kinase 2-beta).

PI51A_HUMAN
θ value	1.98146e-39 (rank : 5)	NC score	0.839822 (rank : 5)
Query Neighborhood Hits	16	Target Neighborhood Hits	22	Shared Neighborhood Hits	12
SwissProt Accessions	Q99755, Q99754, Q99756	Gene names	PIP5K1A
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 5-kinase type-1 alpha (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type I alpha) (PtdIns(4)P- 5-kinase alpha) (PIP5KIalpha) (68 kDa type I phosphatidylinositol-4- phosphate 5-kinase alpha).

PI51A_MOUSE
θ value	2.58786e-39 (rank : 6)	NC score	0.839346 (rank : 7)
Query Neighborhood Hits	16	Target Neighborhood Hits	21	Shared Neighborhood Hits	12
SwissProt Accessions	P70182, Q8K0D3, Q99L80	Gene names	Pip5k1a, Pip5k1b
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 5-kinase type-1 alpha (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type I alpha) (PtdIns(4)P- 5-kinase alpha) (PIP5KIalpha) (Phosphatidylinositol-4-phosphate 5- kinase type I beta) (PI4P5KIbeta) (68 kDa type I phosphatidylinositol- 4-phosphate 5-kinase).

PI51B_MOUSE
θ value	2.86122e-38 (rank : 7)	NC score	0.839458 (rank : 6)
Query Neighborhood Hits	16	Target Neighborhood Hits	15	Shared Neighborhood Hits	12
SwissProt Accessions	P70181, O70335, Q8JZY6	Gene names	Pip5k1b, Pip5k1a
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 5-kinase type-1 beta (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type I beta) (PtdIns(4)P-5- kinase beta) (PIP5KIbeta) (Phosphatidylinositol-4-phosphate 5-kinase type I alpha) (PIP5KIalpha).

PI51B_HUMAN
θ value	8.61488e-35 (rank : 8)	NC score	0.832420 (rank : 8)
Query Neighborhood Hits	16	Target Neighborhood Hits	17	Shared Neighborhood Hits	12
SwissProt Accessions	O14986, P78518, P78519, Q5T5K6, Q5T5K8, Q5T5K9, Q5VZ00, Q7KYT5, Q8NHQ5, Q92749	Gene names	PIP5K1B, STM7
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 5-kinase type-1 beta (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type I beta) (PtdIns(4)P-5- kinase beta) (PIP5KIbeta) (Type I phosphatidylinositol-4-phosphate 5- kinase beta) (Protein STM-7).

PI51C_HUMAN
θ value	1.0531e-32 (rank : 9)	NC score	0.809647 (rank : 10)
Query Neighborhood Hits	16	Target Neighborhood Hits	109	Shared Neighborhood Hits	12
SwissProt Accessions	O60331, Q7LE07	Gene names	PIP5K1C, KIAA0589
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type I gamma) (PtdIns(4)P- 5-kinase gamma) (PtdInsPKIgamma) (PIP5KIgamma).

PI51C_MOUSE
θ value	6.82597e-32 (rank : 10)	NC score	0.816794 (rank : 9)
Query Neighborhood Hits	16	Target Neighborhood Hits	25	Shared Neighborhood Hits	12
SwissProt Accessions	O70161, Q505A1, Q80TW9, Q8VCU5	Gene names	Pip5k1c, Kiaa0589
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type I gamma) (PtdIns(4)P- 5-kinase gamma) (PtdInsPKIgamma) (PIP5KIgamma).

FYV1_HUMAN
θ value	3.29651e-10 (rank : 11)	NC score	0.353079 (rank : 12)
Query Neighborhood Hits	16	Target Neighborhood Hits	217	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y2I7, Q8NB67	Gene names	PIP5K3, KIAA0981, PIKFYVE
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (Phosphatidylinositol-3- phosphate 5-kinase type III) (PIP5K) (PtdIns(4)P-5-kinase) (PIKfyve) (p235).

FYV1_MOUSE
θ value	3.29651e-10 (rank : 12)	NC score	0.363672 (rank : 11)
Query Neighborhood Hits	16	Target Neighborhood Hits	191	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Z1T6	Gene names	Pip5k3, Pikfyve
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (PIP5K) (PtdIns(4)P-5- kinase) (PIKfyve) (p235).

ZN518_HUMAN
θ value	0.365318 (rank : 13)	NC score	0.013099 (rank : 16)
Query Neighborhood Hits	16	Target Neighborhood Hits	780	Shared Neighborhood Hits	3
SwissProt Accessions	Q6AHZ1, O15044, Q32MP4	Gene names	ZNF518, KIAA0335
Domain Architecture	No domain graphic available
Description	Zinc finger protein 518.

RGMB_MOUSE
θ value	1.06291 (rank : 14)	NC score	0.048995 (rank : 13)
Query Neighborhood Hits	16	Target Neighborhood Hits	11	Shared Neighborhood Hits	6
SwissProt Accessions	Q7TQ33, Q8BNR6, Q8CBM7	Gene names	Rgmb
Domain Architecture	No domain graphic available
Description	RGM domain family member B precursor.

RGMB_HUMAN
θ value	1.81305 (rank : 15)	NC score	0.034837 (rank : 14)
Query Neighborhood Hits	16	Target Neighborhood Hits	9	Shared Neighborhood Hits	4
SwissProt Accessions	Q6NW40, Q8NC92	Gene names	RGMB
Domain Architecture	No domain graphic available
Description	RGM domain family member B precursor.

TCAL8_MOUSE
θ value	6.88961 (rank : 16)	NC score	0.014416 (rank : 15)
Query Neighborhood Hits	16	Target Neighborhood Hits	40	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CZY2, Q9CYP9	Gene names	Tceal8
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 8 (TCEA-like protein 8) (Transcription elongation factor S-II protein-like 8).

Hits sorted by NC score

PI52A_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	16	Target Neighborhood Hits	16	Shared Neighborhood Hits	16
SwissProt Accessions	O70172	Gene names	Pip5k2a
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 5-kinase type-2 alpha (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type II alpha) (1- phosphatidylinositol-4-phosphate 5-kinase 2-alpha) (PtdIns(4)P-5- kinase isoform 2-alpha) (PIP5KII-alpha) (Diphosphoinositide kinase 2- alpha).

PI52A_HUMAN
NC score	0.999782 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	16	Target Neighborhood Hits	17	Shared Neighborhood Hits	15
SwissProt Accessions	P48426, P53807, Q5VUX3	Gene names	PIP5K2A, PIP5K2
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 5-kinase type-2 alpha (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type II alpha) (1- phosphatidylinositol-4-phosphate 5-kinase 2-alpha) (PtdIns(4)P-5- kinase isoform 2-alpha) (PIP5KII-alpha) (Diphosphoinositide kinase 2- alpha) (PtdIns(4)P-5-kinase B isoform) (PIP5KIII) (PtdIns(4)P-5-kinase C isoform).

PI52B_MOUSE
NC score	0.996180 (rank : 3)	θ value	2.33393e-165 (rank : 3)
Query Neighborhood Hits	16	Target Neighborhood Hits	20	Shared Neighborhood Hits	13
SwissProt Accessions	Q80XI4, Q8VHB2	Gene names	Pip5k2b
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 5-kinase type-2 beta (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type II beta) (1- phosphatidylinositol-4-phosphate 5-kinase 2-beta) (PtdIns(4)P-5-kinase isoform 2-beta) (PIP5KII-beta) (Diphosphoinositide kinase 2-beta).

PI52B_HUMAN
NC score	0.995815 (rank : 4)	θ value	5.19945e-165 (rank : 4)
Query Neighborhood Hits	16	Target Neighborhood Hits	23	Shared Neighborhood Hits	13
SwissProt Accessions	P78356, Q5U0E8, Q8TBP2	Gene names	PIP5K2B
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 5-kinase type-2 beta (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type II beta) (1- phosphatidylinositol-4-phosphate 5-kinase 2-beta) (PtdIns(4)P-5-kinase isoform 2-beta) (PIP5KII-beta) (Diphosphoinositide kinase 2-beta).

PI51A_HUMAN
NC score	0.839822 (rank : 5)	θ value	1.98146e-39 (rank : 5)
Query Neighborhood Hits	16	Target Neighborhood Hits	22	Shared Neighborhood Hits	12
SwissProt Accessions	Q99755, Q99754, Q99756	Gene names	PIP5K1A
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 5-kinase type-1 alpha (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type I alpha) (PtdIns(4)P- 5-kinase alpha) (PIP5KIalpha) (68 kDa type I phosphatidylinositol-4- phosphate 5-kinase alpha).

PI51B_MOUSE
NC score	0.839458 (rank : 6)	θ value	2.86122e-38 (rank : 7)
Query Neighborhood Hits	16	Target Neighborhood Hits	15	Shared Neighborhood Hits	12
SwissProt Accessions	P70181, O70335, Q8JZY6	Gene names	Pip5k1b, Pip5k1a
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 5-kinase type-1 beta (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type I beta) (PtdIns(4)P-5- kinase beta) (PIP5KIbeta) (Phosphatidylinositol-4-phosphate 5-kinase type I alpha) (PIP5KIalpha).

PI51A_MOUSE
NC score	0.839346 (rank : 7)	θ value	2.58786e-39 (rank : 6)
Query Neighborhood Hits	16	Target Neighborhood Hits	21	Shared Neighborhood Hits	12
SwissProt Accessions	P70182, Q8K0D3, Q99L80	Gene names	Pip5k1a, Pip5k1b
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 5-kinase type-1 alpha (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type I alpha) (PtdIns(4)P- 5-kinase alpha) (PIP5KIalpha) (Phosphatidylinositol-4-phosphate 5- kinase type I beta) (PI4P5KIbeta) (68 kDa type I phosphatidylinositol- 4-phosphate 5-kinase).

PI51B_HUMAN
NC score	0.832420 (rank : 8)	θ value	8.61488e-35 (rank : 8)
Query Neighborhood Hits	16	Target Neighborhood Hits	17	Shared Neighborhood Hits	12
SwissProt Accessions	O14986, P78518, P78519, Q5T5K6, Q5T5K8, Q5T5K9, Q5VZ00, Q7KYT5, Q8NHQ5, Q92749	Gene names	PIP5K1B, STM7
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 5-kinase type-1 beta (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type I beta) (PtdIns(4)P-5- kinase beta) (PIP5KIbeta) (Type I phosphatidylinositol-4-phosphate 5- kinase beta) (Protein STM-7).

PI51C_MOUSE
NC score	0.816794 (rank : 9)	θ value	6.82597e-32 (rank : 10)
Query Neighborhood Hits	16	Target Neighborhood Hits	25	Shared Neighborhood Hits	12
SwissProt Accessions	O70161, Q505A1, Q80TW9, Q8VCU5	Gene names	Pip5k1c, Kiaa0589
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type I gamma) (PtdIns(4)P- 5-kinase gamma) (PtdInsPKIgamma) (PIP5KIgamma).

PI51C_HUMAN
NC score	0.809647 (rank : 10)	θ value	1.0531e-32 (rank : 9)
Query Neighborhood Hits	16	Target Neighborhood Hits	109	Shared Neighborhood Hits	12
SwissProt Accessions	O60331, Q7LE07	Gene names	PIP5K1C, KIAA0589
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type I gamma) (PtdIns(4)P- 5-kinase gamma) (PtdInsPKIgamma) (PIP5KIgamma).

FYV1_MOUSE
NC score	0.363672 (rank : 11)	θ value	3.29651e-10 (rank : 12)
Query Neighborhood Hits	16	Target Neighborhood Hits	191	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Z1T6	Gene names	Pip5k3, Pikfyve
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (PIP5K) (PtdIns(4)P-5- kinase) (PIKfyve) (p235).

FYV1_HUMAN
NC score	0.353079 (rank : 12)	θ value	3.29651e-10 (rank : 11)
Query Neighborhood Hits	16	Target Neighborhood Hits	217	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y2I7, Q8NB67	Gene names	PIP5K3, KIAA0981, PIKFYVE
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (Phosphatidylinositol-3- phosphate 5-kinase type III) (PIP5K) (PtdIns(4)P-5-kinase) (PIKfyve) (p235).

RGMB_MOUSE
NC score	0.048995 (rank : 13)	θ value	1.06291 (rank : 14)
Query Neighborhood Hits	16	Target Neighborhood Hits	11	Shared Neighborhood Hits	6
SwissProt Accessions	Q7TQ33, Q8BNR6, Q8CBM7	Gene names	Rgmb
Domain Architecture	No domain graphic available
Description	RGM domain family member B precursor.

RGMB_HUMAN
NC score	0.034837 (rank : 14)	θ value	1.81305 (rank : 15)
Query Neighborhood Hits	16	Target Neighborhood Hits	9	Shared Neighborhood Hits	4
SwissProt Accessions	Q6NW40, Q8NC92	Gene names	RGMB
Domain Architecture	No domain graphic available
Description	RGM domain family member B precursor.

TCAL8_MOUSE
NC score	0.014416 (rank : 15)	θ value	6.88961 (rank : 16)
Query Neighborhood Hits	16	Target Neighborhood Hits	40	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CZY2, Q9CYP9	Gene names	Tceal8
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 8 (TCEA-like protein 8) (Transcription elongation factor S-II protein-like 8).

ZN518_HUMAN
NC score	0.013099 (rank : 16)	θ value	0.365318 (rank : 13)
Query Neighborhood Hits	16	Target Neighborhood Hits	780	Shared Neighborhood Hits	3
SwissProt Accessions	Q6AHZ1, O15044, Q32MP4	Gene names	ZNF518, KIAA0335
Domain Architecture	No domain graphic available
Description	Zinc finger protein 518.