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Network neighborhood for query Sequence : PI51B_HUMAN

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PI51B_HUMAN
SwissProt Accessions	O14986, P78518, P78519, Q5T5K6, Q5T5K8, Q5T5K9, Q5VZ00, Q7KYT5, Q8NHQ5, Q92749	Gene names	PIP5K1B, STM7
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 5-kinase type-1 beta (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type I beta) (PtdIns(4)P-5- kinase beta) (PIP5KIbeta) (Type I phosphatidylinositol-4-phosphate 5- kinase beta) (Protein STM-7).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PI51B_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	17	Target Neighborhood Hits	17	Shared Neighborhood Hits	17
SwissProt Accessions	O14986, P78518, P78519, Q5T5K6, Q5T5K8, Q5T5K9, Q5VZ00, Q7KYT5, Q8NHQ5, Q92749	Gene names	PIP5K1B, STM7
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 5-kinase type-1 beta (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type I beta) (PtdIns(4)P-5- kinase beta) (PIP5KIbeta) (Type I phosphatidylinositol-4-phosphate 5- kinase beta) (Protein STM-7).

PI51B_MOUSE
θ value	0 (rank : 2)	NC score	0.999666 (rank : 2)
Query Neighborhood Hits	17	Target Neighborhood Hits	15	Shared Neighborhood Hits	13
SwissProt Accessions	P70181, O70335, Q8JZY6	Gene names	Pip5k1b, Pip5k1a
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 5-kinase type-1 beta (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type I beta) (PtdIns(4)P-5- kinase beta) (PIP5KIbeta) (Phosphatidylinositol-4-phosphate 5-kinase type I alpha) (PIP5KIalpha).

PI51C_MOUSE
θ value	3.47146e-177 (rank : 3)	NC score	0.991549 (rank : 5)
Query Neighborhood Hits	17	Target Neighborhood Hits	25	Shared Neighborhood Hits	12
SwissProt Accessions	O70161, Q505A1, Q80TW9, Q8VCU5	Gene names	Pip5k1c, Kiaa0589
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type I gamma) (PtdIns(4)P- 5-kinase gamma) (PtdInsPKIgamma) (PIP5KIgamma).

PI51C_HUMAN
θ value	2.48782e-175 (rank : 4)	NC score	0.980909 (rank : 6)
Query Neighborhood Hits	17	Target Neighborhood Hits	109	Shared Neighborhood Hits	12
SwissProt Accessions	O60331, Q7LE07	Gene names	PIP5K1C, KIAA0589
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type I gamma) (PtdIns(4)P- 5-kinase gamma) (PtdInsPKIgamma) (PIP5KIgamma).

PI51A_MOUSE
θ value	3.5924e-174 (rank : 5)	NC score	0.992849 (rank : 3)
Query Neighborhood Hits	17	Target Neighborhood Hits	21	Shared Neighborhood Hits	12
SwissProt Accessions	P70182, Q8K0D3, Q99L80	Gene names	Pip5k1a, Pip5k1b
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 5-kinase type-1 alpha (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type I alpha) (PtdIns(4)P- 5-kinase alpha) (PIP5KIalpha) (Phosphatidylinositol-4-phosphate 5- kinase type I beta) (PI4P5KIbeta) (68 kDa type I phosphatidylinositol- 4-phosphate 5-kinase).

PI51A_HUMAN
θ value	2.49359e-167 (rank : 6)	NC score	0.991627 (rank : 4)
Query Neighborhood Hits	17	Target Neighborhood Hits	22	Shared Neighborhood Hits	12
SwissProt Accessions	Q99755, Q99754, Q99756	Gene names	PIP5K1A
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 5-kinase type-1 alpha (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type I alpha) (PtdIns(4)P- 5-kinase alpha) (PIP5KIalpha) (68 kDa type I phosphatidylinositol-4- phosphate 5-kinase alpha).

PI52B_MOUSE
θ value	4.71619e-41 (rank : 7)	NC score	0.843749 (rank : 7)
Query Neighborhood Hits	17	Target Neighborhood Hits	20	Shared Neighborhood Hits	12
SwissProt Accessions	Q80XI4, Q8VHB2	Gene names	Pip5k2b
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 5-kinase type-2 beta (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type II beta) (1- phosphatidylinositol-4-phosphate 5-kinase 2-beta) (PtdIns(4)P-5-kinase isoform 2-beta) (PIP5KII-beta) (Diphosphoinositide kinase 2-beta).

PI52B_HUMAN
θ value	8.04462e-41 (rank : 8)	NC score	0.843337 (rank : 8)
Query Neighborhood Hits	17	Target Neighborhood Hits	23	Shared Neighborhood Hits	12
SwissProt Accessions	P78356, Q5U0E8, Q8TBP2	Gene names	PIP5K2B
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 5-kinase type-2 beta (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type II beta) (1- phosphatidylinositol-4-phosphate 5-kinase 2-beta) (PtdIns(4)P-5-kinase isoform 2-beta) (PIP5KII-beta) (Diphosphoinositide kinase 2-beta).

PI52A_HUMAN
θ value	5.0505e-35 (rank : 9)	NC score	0.834280 (rank : 9)
Query Neighborhood Hits	17	Target Neighborhood Hits	17	Shared Neighborhood Hits	12
SwissProt Accessions	P48426, P53807, Q5VUX3	Gene names	PIP5K2A, PIP5K2
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 5-kinase type-2 alpha (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type II alpha) (1- phosphatidylinositol-4-phosphate 5-kinase 2-alpha) (PtdIns(4)P-5- kinase isoform 2-alpha) (PIP5KII-alpha) (Diphosphoinositide kinase 2- alpha) (PtdIns(4)P-5-kinase B isoform) (PIP5KIII) (PtdIns(4)P-5-kinase C isoform).

PI52A_MOUSE
θ value	8.61488e-35 (rank : 10)	NC score	0.832420 (rank : 10)
Query Neighborhood Hits	17	Target Neighborhood Hits	16	Shared Neighborhood Hits	12
SwissProt Accessions	O70172	Gene names	Pip5k2a
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 5-kinase type-2 alpha (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type II alpha) (1- phosphatidylinositol-4-phosphate 5-kinase 2-alpha) (PtdIns(4)P-5- kinase isoform 2-alpha) (PIP5KII-alpha) (Diphosphoinositide kinase 2- alpha).

FYV1_MOUSE
θ value	2.36244e-08 (rank : 11)	NC score	0.330735 (rank : 11)
Query Neighborhood Hits	17	Target Neighborhood Hits	191	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Z1T6	Gene names	Pip5k3, Pikfyve
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (PIP5K) (PtdIns(4)P-5- kinase) (PIKfyve) (p235).

FYV1_HUMAN
θ value	8.97725e-08 (rank : 12)	NC score	0.319226 (rank : 12)
Query Neighborhood Hits	17	Target Neighborhood Hits	217	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y2I7, Q8NB67	Gene names	PIP5K3, KIAA0981, PIKFYVE
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (Phosphatidylinositol-3- phosphate 5-kinase type III) (PIP5K) (PtdIns(4)P-5-kinase) (PIKfyve) (p235).

MTF1_MOUSE
θ value	4.03905 (rank : 13)	NC score	0.000159 (rank : 16)
Query Neighborhood Hits	17	Target Neighborhood Hits	785	Shared Neighborhood Hits	4
SwissProt Accessions	Q07243	Gene names	Mtf1, Mtf-1
Domain Architecture	No domain graphic available
Description	Metal-regulatory transcription factor 1 (Transcription factor MTF-1) (MRE-binding transcription factor).

MTF1_HUMAN
θ value	6.88961 (rank : 14)	NC score	-0.000166 (rank : 17)
Query Neighborhood Hits	17	Target Neighborhood Hits	814	Shared Neighborhood Hits	4
SwissProt Accessions	Q14872, Q96CB1	Gene names	MTF1
Domain Architecture	No domain graphic available
Description	Metal-regulatory transcription factor 1 (Transcription factor MTF-1) (MRE-binding transcription factor).

ZEP2_HUMAN
θ value	6.88961 (rank : 15)	NC score	0.000910 (rank : 15)
Query Neighborhood Hits	17	Target Neighborhood Hits	937	Shared Neighborhood Hits	5
SwissProt Accessions	P31629, Q02646, Q5THT5, Q9NS05	Gene names	HIVEP2
Domain Architecture	No domain graphic available
Description	Human immunodeficiency virus type I enhancer-binding protein 2 (HIV- EP2) (MHC-binding protein 2) (MBP-2).

SRGP1_HUMAN
θ value	8.99809 (rank : 16)	NC score	0.006423 (rank : 14)
Query Neighborhood Hits	17	Target Neighborhood Hits	390	Shared Neighborhood Hits	4
SwissProt Accessions	Q7Z6B7, Q9H8A3, Q9P2P2	Gene names	SRGAP1, ARHGAP13, KIAA1304
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho-GTPase- activating protein 13).

ZN318_MOUSE
θ value	8.99809 (rank : 17)	NC score	0.008131 (rank : 13)
Query Neighborhood Hits	17	Target Neighborhood Hits	642	Shared Neighborhood Hits	4
SwissProt Accessions	Q99PP2, Q3TZL5, Q9JJ01	Gene names	Znf318, Tzf, Zfp318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Testicular zinc finger protein).

Hits sorted by NC score

PI51B_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	17	Target Neighborhood Hits	17	Shared Neighborhood Hits	17
SwissProt Accessions	O14986, P78518, P78519, Q5T5K6, Q5T5K8, Q5T5K9, Q5VZ00, Q7KYT5, Q8NHQ5, Q92749	Gene names	PIP5K1B, STM7
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 5-kinase type-1 beta (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type I beta) (PtdIns(4)P-5- kinase beta) (PIP5KIbeta) (Type I phosphatidylinositol-4-phosphate 5- kinase beta) (Protein STM-7).

PI51B_MOUSE
NC score	0.999666 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	17	Target Neighborhood Hits	15	Shared Neighborhood Hits	13
SwissProt Accessions	P70181, O70335, Q8JZY6	Gene names	Pip5k1b, Pip5k1a
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 5-kinase type-1 beta (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type I beta) (PtdIns(4)P-5- kinase beta) (PIP5KIbeta) (Phosphatidylinositol-4-phosphate 5-kinase type I alpha) (PIP5KIalpha).

PI51A_MOUSE
NC score	0.992849 (rank : 3)	θ value	3.5924e-174 (rank : 5)
Query Neighborhood Hits	17	Target Neighborhood Hits	21	Shared Neighborhood Hits	12
SwissProt Accessions	P70182, Q8K0D3, Q99L80	Gene names	Pip5k1a, Pip5k1b
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 5-kinase type-1 alpha (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type I alpha) (PtdIns(4)P- 5-kinase alpha) (PIP5KIalpha) (Phosphatidylinositol-4-phosphate 5- kinase type I beta) (PI4P5KIbeta) (68 kDa type I phosphatidylinositol- 4-phosphate 5-kinase).

PI51A_HUMAN
NC score	0.991627 (rank : 4)	θ value	2.49359e-167 (rank : 6)
Query Neighborhood Hits	17	Target Neighborhood Hits	22	Shared Neighborhood Hits	12
SwissProt Accessions	Q99755, Q99754, Q99756	Gene names	PIP5K1A
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 5-kinase type-1 alpha (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type I alpha) (PtdIns(4)P- 5-kinase alpha) (PIP5KIalpha) (68 kDa type I phosphatidylinositol-4- phosphate 5-kinase alpha).

PI51C_MOUSE
NC score	0.991549 (rank : 5)	θ value	3.47146e-177 (rank : 3)
Query Neighborhood Hits	17	Target Neighborhood Hits	25	Shared Neighborhood Hits	12
SwissProt Accessions	O70161, Q505A1, Q80TW9, Q8VCU5	Gene names	Pip5k1c, Kiaa0589
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type I gamma) (PtdIns(4)P- 5-kinase gamma) (PtdInsPKIgamma) (PIP5KIgamma).

PI51C_HUMAN
NC score	0.980909 (rank : 6)	θ value	2.48782e-175 (rank : 4)
Query Neighborhood Hits	17	Target Neighborhood Hits	109	Shared Neighborhood Hits	12
SwissProt Accessions	O60331, Q7LE07	Gene names	PIP5K1C, KIAA0589
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type I gamma) (PtdIns(4)P- 5-kinase gamma) (PtdInsPKIgamma) (PIP5KIgamma).

PI52B_MOUSE
NC score	0.843749 (rank : 7)	θ value	4.71619e-41 (rank : 7)
Query Neighborhood Hits	17	Target Neighborhood Hits	20	Shared Neighborhood Hits	12
SwissProt Accessions	Q80XI4, Q8VHB2	Gene names	Pip5k2b
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 5-kinase type-2 beta (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type II beta) (1- phosphatidylinositol-4-phosphate 5-kinase 2-beta) (PtdIns(4)P-5-kinase isoform 2-beta) (PIP5KII-beta) (Diphosphoinositide kinase 2-beta).

PI52B_HUMAN
NC score	0.843337 (rank : 8)	θ value	8.04462e-41 (rank : 8)
Query Neighborhood Hits	17	Target Neighborhood Hits	23	Shared Neighborhood Hits	12
SwissProt Accessions	P78356, Q5U0E8, Q8TBP2	Gene names	PIP5K2B
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 5-kinase type-2 beta (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type II beta) (1- phosphatidylinositol-4-phosphate 5-kinase 2-beta) (PtdIns(4)P-5-kinase isoform 2-beta) (PIP5KII-beta) (Diphosphoinositide kinase 2-beta).

PI52A_HUMAN
NC score	0.834280 (rank : 9)	θ value	5.0505e-35 (rank : 9)
Query Neighborhood Hits	17	Target Neighborhood Hits	17	Shared Neighborhood Hits	12
SwissProt Accessions	P48426, P53807, Q5VUX3	Gene names	PIP5K2A, PIP5K2
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 5-kinase type-2 alpha (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type II alpha) (1- phosphatidylinositol-4-phosphate 5-kinase 2-alpha) (PtdIns(4)P-5- kinase isoform 2-alpha) (PIP5KII-alpha) (Diphosphoinositide kinase 2- alpha) (PtdIns(4)P-5-kinase B isoform) (PIP5KIII) (PtdIns(4)P-5-kinase C isoform).

PI52A_MOUSE
NC score	0.832420 (rank : 10)	θ value	8.61488e-35 (rank : 10)
Query Neighborhood Hits	17	Target Neighborhood Hits	16	Shared Neighborhood Hits	12
SwissProt Accessions	O70172	Gene names	Pip5k2a
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 5-kinase type-2 alpha (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type II alpha) (1- phosphatidylinositol-4-phosphate 5-kinase 2-alpha) (PtdIns(4)P-5- kinase isoform 2-alpha) (PIP5KII-alpha) (Diphosphoinositide kinase 2- alpha).

FYV1_MOUSE
NC score	0.330735 (rank : 11)	θ value	2.36244e-08 (rank : 11)
Query Neighborhood Hits	17	Target Neighborhood Hits	191	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Z1T6	Gene names	Pip5k3, Pikfyve
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (PIP5K) (PtdIns(4)P-5- kinase) (PIKfyve) (p235).

FYV1_HUMAN
NC score	0.319226 (rank : 12)	θ value	8.97725e-08 (rank : 12)
Query Neighborhood Hits	17	Target Neighborhood Hits	217	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y2I7, Q8NB67	Gene names	PIP5K3, KIAA0981, PIKFYVE
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (Phosphatidylinositol-3- phosphate 5-kinase type III) (PIP5K) (PtdIns(4)P-5-kinase) (PIKfyve) (p235).

ZN318_MOUSE
NC score	0.008131 (rank : 13)	θ value	8.99809 (rank : 17)
Query Neighborhood Hits	17	Target Neighborhood Hits	642	Shared Neighborhood Hits	4
SwissProt Accessions	Q99PP2, Q3TZL5, Q9JJ01	Gene names	Znf318, Tzf, Zfp318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Testicular zinc finger protein).

SRGP1_HUMAN
NC score	0.006423 (rank : 14)	θ value	8.99809 (rank : 16)
Query Neighborhood Hits	17	Target Neighborhood Hits	390	Shared Neighborhood Hits	4
SwissProt Accessions	Q7Z6B7, Q9H8A3, Q9P2P2	Gene names	SRGAP1, ARHGAP13, KIAA1304
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho-GTPase- activating protein 13).

ZEP2_HUMAN
NC score	0.000910 (rank : 15)	θ value	6.88961 (rank : 15)
Query Neighborhood Hits	17	Target Neighborhood Hits	937	Shared Neighborhood Hits	5
SwissProt Accessions	P31629, Q02646, Q5THT5, Q9NS05	Gene names	HIVEP2
Domain Architecture	No domain graphic available
Description	Human immunodeficiency virus type I enhancer-binding protein 2 (HIV- EP2) (MHC-binding protein 2) (MBP-2).

MTF1_MOUSE
NC score	0.000159 (rank : 16)	θ value	4.03905 (rank : 13)
Query Neighborhood Hits	17	Target Neighborhood Hits	785	Shared Neighborhood Hits	4
SwissProt Accessions	Q07243	Gene names	Mtf1, Mtf-1
Domain Architecture	No domain graphic available
Description	Metal-regulatory transcription factor 1 (Transcription factor MTF-1) (MRE-binding transcription factor).

MTF1_HUMAN
NC score	-0.000166 (rank : 17)	θ value	6.88961 (rank : 14)
Query Neighborhood Hits	17	Target Neighborhood Hits	814	Shared Neighborhood Hits	4
SwissProt Accessions	Q14872, Q96CB1	Gene names	MTF1
Domain Architecture	No domain graphic available
Description	Metal-regulatory transcription factor 1 (Transcription factor MTF-1) (MRE-binding transcription factor).