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Network neighborhood for query Sequence : NVL_HUMAN

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NVL_HUMAN
SwissProt Accessions	O15381, Q96EM7	Gene names	NVL
Domain Architecture
Description	Nuclear valosin-containing protein-like (Nuclear VCP-like protein) (NVLp).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

NVL_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	112	Target Neighborhood Hits	112	Shared Neighborhood Hits	112
SwissProt Accessions	O15381, Q96EM7	Gene names	NVL
Domain Architecture
Description	Nuclear valosin-containing protein-like (Nuclear VCP-like protein) (NVLp).

NVL_MOUSE
θ value	0 (rank : 2)	NC score	0.997992 (rank : 2)
Query Neighborhood Hits	112	Target Neighborhood Hits	110	Shared Neighborhood Hits	86
SwissProt Accessions	Q9DBY8, Q3USC4, Q8BW27, Q8K2B5	Gene names	Nvl
Domain Architecture
Description	Nuclear valosin-containing protein-like (Nuclear VCP-like protein) (NVLp).

TERA_MOUSE
θ value	2.35568e-133 (rank : 3)	NC score	0.982065 (rank : 3)
Query Neighborhood Hits	112	Target Neighborhood Hits	76	Shared Neighborhood Hits	69
SwissProt Accessions	Q01853	Gene names	Vcp
Domain Architecture
Description	Transitional endoplasmic reticulum ATPase (TER ATPase) (15S Mg(2+)- ATPase p97 subunit) (Valosin-containing protein) (VCP).

TERA_HUMAN
θ value	3.07662e-133 (rank : 4)	NC score	0.982049 (rank : 4)
Query Neighborhood Hits	112	Target Neighborhood Hits	76	Shared Neighborhood Hits	69
SwissProt Accessions	P55072, Q969G7	Gene names	VCP
Domain Architecture
Description	Transitional endoplasmic reticulum ATPase (TER ATPase) (15S Mg(2+)- ATPase p97 subunit) (Valosin-containing protein) (VCP).

PEX6_HUMAN
θ value	3.69378e-78 (rank : 5)	NC score	0.959834 (rank : 5)
Query Neighborhood Hits	112	Target Neighborhood Hits	99	Shared Neighborhood Hits	73
SwissProt Accessions	Q13608, Q8WYQ2, Q99476	Gene names	PEX6, PXAAA1
Domain Architecture
Description	Peroxisome assembly factor 2 (PAF-2) (Peroxisomal-type ATPase 1) (Peroxin-6) (Peroxisomal biogenesis factor 6).

PEX6_MOUSE
θ value	1.18825e-76 (rank : 6)	NC score	0.959120 (rank : 6)
Query Neighborhood Hits	112	Target Neighborhood Hits	94	Shared Neighborhood Hits	71
SwissProt Accessions	Q99LC9, Q6YNQ9	Gene names	Pex6
Domain Architecture	No domain graphic available
Description	Peroxisome assembly factor 2 (PAF-2) (Peroxisomal-type ATPase 1) (Peroxin-6) (Peroxisomal biogenesis factor 6).

PEX1_HUMAN
θ value	4.10295e-61 (rank : 7)	NC score	0.957210 (rank : 7)
Query Neighborhood Hits	112	Target Neighborhood Hits	98	Shared Neighborhood Hits	64
SwissProt Accessions	O43933, Q96S71, Q96S72, Q96S73, Q99994	Gene names	PEX1
Domain Architecture
Description	Peroxisome biogenesis factor 1 (Peroxin-1) (Peroxisome biogenesis disorder protein 1).

PRS6B_HUMAN
θ value	9.81109e-47 (rank : 8)	NC score	0.938714 (rank : 16)
Query Neighborhood Hits	112	Target Neighborhood Hits	85	Shared Neighborhood Hits	59
SwissProt Accessions	P43686, Q96FV5, Q9UBM3, Q9UEX3	Gene names	PSMC4, TBP7
Domain Architecture
Description	26S protease regulatory subunit 6B (Proteasome 26S subunit ATPase 4) (MIP224) (MB67-interacting protein) (TAT-binding protein 7) (TBP-7).

PRS6B_MOUSE
θ value	1.41672e-45 (rank : 9)	NC score	0.938151 (rank : 17)
Query Neighborhood Hits	112	Target Neighborhood Hits	89	Shared Neighborhood Hits	59
SwissProt Accessions	P54775	Gene names	Psmc4, Tbp7
Domain Architecture
Description	26S protease regulatory subunit 6B (Proteasome 26S subunit ATPase 4) (MIP224) (MB67-interacting protein) (TAT-binding protein 7) (TBP-7) (CIP21).

AFG31_MOUSE
θ value	7.03111e-45 (rank : 10)	NC score	0.927585 (rank : 23)
Query Neighborhood Hits	112	Target Neighborhood Hits	74	Shared Neighborhood Hits	64
SwissProt Accessions	Q920A7	Gene names	Afg3l1
Domain Architecture
Description	AFG3-like protein 1 (EC 3.4.24.-).

AFG32_HUMAN
θ value	1.19932e-44 (rank : 11)	NC score	0.923986 (rank : 26)
Query Neighborhood Hits	112	Target Neighborhood Hits	72	Shared Neighborhood Hits	64
SwissProt Accessions	Q9Y4W6	Gene names	AFG3L2
Domain Architecture
Description	AFG3-like protein 2 (EC 3.4.24.-) (Paraplegin-like protein).

PRS10_HUMAN
θ value	1.56636e-44 (rank : 12)	NC score	0.943408 (rank : 8)
Query Neighborhood Hits	112	Target Neighborhood Hits	95	Shared Neighborhood Hits	71
SwissProt Accessions	P62333, P49719, Q6IBU3, Q92524	Gene names	PSMC6, SUG2
Domain Architecture
Description	26S protease regulatory subunit S10B (Proteasome subunit p42) (Proteasome 26S subunit ATPase 6).

PRS10_MOUSE
θ value	1.56636e-44 (rank : 13)	NC score	0.943408 (rank : 9)
Query Neighborhood Hits	112	Target Neighborhood Hits	95	Shared Neighborhood Hits	71
SwissProt Accessions	P62334, P49719, Q3TKK1, Q810A6, Q92524, Q9CXH9	Gene names	Psmc6, Sug2
Domain Architecture
Description	26S protease regulatory subunit S10B (Proteasome subunit p42) (Proteasome 26S subunit ATPase 6).

AFG32_MOUSE
θ value	3.48949e-44 (rank : 14)	NC score	0.923723 (rank : 27)
Query Neighborhood Hits	112	Target Neighborhood Hits	73	Shared Neighborhood Hits	64
SwissProt Accessions	Q8JZQ2	Gene names	Afg3l2
Domain Architecture	No domain graphic available
Description	AFG3-like protein 2 (EC 3.4.24.-).

PRS7_HUMAN
θ value	7.77379e-44 (rank : 15)	NC score	0.938969 (rank : 14)
Query Neighborhood Hits	112	Target Neighborhood Hits	66	Shared Neighborhood Hits	62
SwissProt Accessions	P35998	Gene names	PSMC2, MSS1
Domain Architecture
Description	26S protease regulatory subunit 7 (Proteasome 26S subunit ATPase 2) (Protein MSS1).

PRS7_MOUSE
θ value	7.77379e-44 (rank : 16)	NC score	0.938960 (rank : 15)
Query Neighborhood Hits	112	Target Neighborhood Hits	67	Shared Neighborhood Hits	62
SwissProt Accessions	P46471, O08531, Q3TGX5, Q9DBA1	Gene names	Psmc2, Mss1
Domain Architecture
Description	26S protease regulatory subunit 7 (Proteasome 26S subunit ATPase 2) (Protein MSS1).

ATAD2_MOUSE
θ value	6.58091e-43 (rank : 17)	NC score	0.886130 (rank : 40)
Query Neighborhood Hits	112	Target Neighborhood Hits	167	Shared Neighborhood Hits	61
SwissProt Accessions	Q8CDM1	Gene names	Atad2
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 2.

PRS6A_HUMAN
θ value	8.59492e-43 (rank : 18)	NC score	0.937594 (rank : 19)
Query Neighborhood Hits	112	Target Neighborhood Hits	87	Shared Neighborhood Hits	61
SwissProt Accessions	P17980, Q96HD3	Gene names	PSMC3, TBP1
Domain Architecture
Description	26S protease regulatory subunit 6A (Proteasome 26S subunit ATPase 3) (TAT-binding protein 1) (TBP-1) (Proteasome subunit P50).

PRS6A_MOUSE
θ value	1.12253e-42 (rank : 19)	NC score	0.937692 (rank : 18)
Query Neighborhood Hits	112	Target Neighborhood Hits	85	Shared Neighborhood Hits	61
SwissProt Accessions	O88685	Gene names	Psmc3, Tbp1
Domain Architecture
Description	26S protease regulatory subunit 6A (Proteasome 26S subunit ATPase 3) (TAT-binding protein 1) (TBP-1).

ATAD2_HUMAN
θ value	1.46607e-42 (rank : 20)	NC score	0.869038 (rank : 41)
Query Neighborhood Hits	112	Target Neighborhood Hits	322	Shared Neighborhood Hits	66
SwissProt Accessions	Q6PL18, Q658P2, Q68CQ0, Q6PJV6, Q8N890, Q9UHS5	Gene names	ATAD2
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 2.

KATL1_HUMAN
θ value	3.26607e-42 (rank : 21)	NC score	0.925111 (rank : 25)
Query Neighborhood Hits	112	Target Neighborhood Hits	80	Shared Neighborhood Hits	68
SwissProt Accessions	Q9BW62	Gene names	KATNAL1
Domain Architecture	No domain graphic available
Description	Katanin p60 ATPase-containing subunit A-like 1 (EC 3.6.4.3) (Katanin p60 subunit A-like 1) (p60 katanin-like 1).

PRS4_HUMAN
θ value	4.2656e-42 (rank : 22)	NC score	0.939983 (rank : 10)
Query Neighborhood Hits	112	Target Neighborhood Hits	84	Shared Neighborhood Hits	65
SwissProt Accessions	P62191, P49014, Q03527, Q6IAW0, Q96AZ3	Gene names	PSMC1
Domain Architecture
Description	26S protease regulatory subunit 4 (P26s4) (Proteasome 26S subunit ATPase 1).

PRS4_MOUSE
θ value	4.2656e-42 (rank : 23)	NC score	0.939983 (rank : 11)
Query Neighborhood Hits	112	Target Neighborhood Hits	84	Shared Neighborhood Hits	65
SwissProt Accessions	P62192, P49014, Q03527, Q96AZ3	Gene names	Psmc1
Domain Architecture
Description	26S protease regulatory subunit 4 (P26s4) (Proteasome 26S subunit ATPase 1).

SPG7_HUMAN
θ value	5.57106e-42 (rank : 24)	NC score	0.928117 (rank : 22)
Query Neighborhood Hits	112	Target Neighborhood Hits	71	Shared Neighborhood Hits	60
SwissProt Accessions	Q9UQ90, O75756, Q96IB0	Gene names	SPG7, CAR, CMAR, PGN
Domain Architecture
Description	Paraplegin (EC 3.4.24.-) (Spastic paraplegia protein 7).

KATL1_MOUSE
θ value	7.27602e-42 (rank : 25)	NC score	0.925337 (rank : 24)
Query Neighborhood Hits	112	Target Neighborhood Hits	77	Shared Neighborhood Hits	68
SwissProt Accessions	Q8K0T4	Gene names	Katnal1
Domain Architecture	No domain graphic available
Description	Katanin p60 ATPase-containing subunit A-like 1 (EC 3.6.4.3) (Katanin p60 subunit A-like 1) (p60 katanin-like 1).

PRS8_HUMAN
θ value	3.61106e-41 (rank : 26)	NC score	0.939766 (rank : 12)
Query Neighborhood Hits	112	Target Neighborhood Hits	117	Shared Neighborhood Hits	67
SwissProt Accessions	P62195, O35051, O43208, P47210, P52915, P52916	Gene names	PSMC5, SUG1
Domain Architecture
Description	26S protease regulatory subunit 8 (Proteasome 26S subunit ATPase 5) (Proteasome subunit p45) (p45/SUG) (Thyroid hormone receptor- interacting protein 1) (TRIP1).

PRS8_MOUSE
θ value	3.61106e-41 (rank : 27)	NC score	0.939766 (rank : 13)
Query Neighborhood Hits	112	Target Neighborhood Hits	117	Shared Neighborhood Hits	67
SwissProt Accessions	P62196, O35051, P47210, P52915, P52916, Q3UL51, Q9CWN5	Gene names	Psmc5, Sug1
Domain Architecture
Description	26S protease regulatory subunit 8 (Proteasome 26S subunit ATPase 5) (Proteasome subunit p45) (p45/SUG) (mSUG1).

KTNA1_HUMAN
θ value	5.76516e-39 (rank : 28)	NC score	0.919351 (rank : 29)
Query Neighborhood Hits	112	Target Neighborhood Hits	117	Shared Neighborhood Hits	66
SwissProt Accessions	O75449, Q5TFA8, Q5TFA9, Q86VN2, Q9NU52	Gene names	KATNA1
Domain Architecture	No domain graphic available
Description	Katanin p60 ATPase-containing subunit A1 (EC 3.6.4.3) (Katanin p60 subunit A1) (p60 katanin).

KTNA1_MOUSE
θ value	7.52953e-39 (rank : 29)	NC score	0.917151 (rank : 31)
Query Neighborhood Hits	112	Target Neighborhood Hits	123	Shared Neighborhood Hits	66
SwissProt Accessions	Q9WV86	Gene names	Katna1
Domain Architecture	No domain graphic available
Description	Katanin p60 ATPase-containing subunit A1 (EC 3.6.4.3) (Katanin p60 subunit A1) (p60 katanin) (Lipotransin).

YMEL1_HUMAN
θ value	2.42216e-37 (rank : 30)	NC score	0.917961 (rank : 30)
Query Neighborhood Hits	112	Target Neighborhood Hits	73	Shared Neighborhood Hits	62
SwissProt Accessions	Q96TA2, Q9H1Q0, Q9UMR9	Gene names	YME1L1, FTSH1, YME1L
Domain Architecture
Description	ATP-dependent metalloprotease YME1L1 (EC 3.4.24.-) (YME1-like protein 1) (ATP-dependent metalloprotease FtsH1) (Meg-4) (Presenilin- associated metalloprotease) (PAMP).

YMEL1_MOUSE
θ value	7.04741e-37 (rank : 31)	NC score	0.921199 (rank : 28)
Query Neighborhood Hits	112	Target Neighborhood Hits	76	Shared Neighborhood Hits	62
SwissProt Accessions	O88967, Q7TNN5	Gene names	Yme1l1
Domain Architecture
Description	ATP-dependent metalloprotease YME1L1 (EC 3.4.24.-) (YME1-like protein 1) (ATP-dependent metalloprotease FtsH1).

SPAST_MOUSE
θ value	2.67802e-36 (rank : 32)	NC score	0.913628 (rank : 35)
Query Neighborhood Hits	112	Target Neighborhood Hits	138	Shared Neighborhood Hits	65
SwissProt Accessions	Q9QYY8, Q6ZPY6, Q80VE0, Q9CVK0	Gene names	Spast, Kiaa1083, Spg4
Domain Architecture	No domain graphic available
Description	Spastin.

SPAST_HUMAN
θ value	5.96599e-36 (rank : 33)	NC score	0.914372 (rank : 34)
Query Neighborhood Hits	112	Target Neighborhood Hits	100	Shared Neighborhood Hits	62
SwissProt Accessions	Q9UBP0, Q9UPR9	Gene names	SPAST, KIAA1083, SPG4
Domain Architecture
Description	Spastin.

VPS4B_HUMAN
θ value	5.96599e-36 (rank : 34)	NC score	0.909752 (rank : 36)
Query Neighborhood Hits	112	Target Neighborhood Hits	87	Shared Neighborhood Hits	63
SwissProt Accessions	O75351, Q9GZS7	Gene names	VPS4B, SKD1, VPS42
Domain Architecture
Description	Vacuolar protein sorting-associating protein 4B (Protein SKD1).

ATAD1_HUMAN
θ value	2.26708e-35 (rank : 35)	NC score	0.932871 (rank : 20)
Query Neighborhood Hits	112	Target Neighborhood Hits	75	Shared Neighborhood Hits	67
SwissProt Accessions	Q8NBU5, Q6P4B9, Q8N3G1, Q8WYR9, Q969Y3	Gene names	ATAD1
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 1.

ATAD1_MOUSE
θ value	2.26708e-35 (rank : 36)	NC score	0.932871 (rank : 21)
Query Neighborhood Hits	112	Target Neighborhood Hits	75	Shared Neighborhood Hits	67
SwissProt Accessions	Q9D5T0, Q3U8V2, Q9D7A4	Gene names	Atad1
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 1.

VPS4B_MOUSE
θ value	2.96089e-35 (rank : 37)	NC score	0.908901 (rank : 37)
Query Neighborhood Hits	112	Target Neighborhood Hits	86	Shared Neighborhood Hits	64
SwissProt Accessions	P46467, Q91W22, Q9R1C9	Gene names	Vps4b, Skd1
Domain Architecture
Description	Vacuolar protein sorting-associating protein 4B (Protein SKD1).

NSF_HUMAN
θ value	3.86705e-35 (rank : 38)	NC score	0.916468 (rank : 33)
Query Neighborhood Hits	112	Target Neighborhood Hits	74	Shared Neighborhood Hits	65
SwissProt Accessions	P46459, Q9UKZ2	Gene names	NSF
Domain Architecture
Description	Vesicle-fusing ATPase (EC 3.6.4.6) (Vesicular-fusion protein NSF) (N- ethylmaleimide sensitive fusion protein) (NEM-sensitive fusion protein).

NSF_MOUSE
θ value	6.59618e-35 (rank : 39)	NC score	0.916492 (rank : 32)
Query Neighborhood Hits	112	Target Neighborhood Hits	73	Shared Neighborhood Hits	62
SwissProt Accessions	P46460	Gene names	Nsf, Skd2
Domain Architecture
Description	Vesicle-fusing ATPase (EC 3.6.4.6) (Vesicular-fusion protein NSF) (N- ethylmaleimide sensitive fusion protein) (NEM-sensitive fusion protein) (SKD2 protein).

VPS4A_HUMAN
θ value	3.27365e-34 (rank : 40)	NC score	0.907512 (rank : 39)
Query Neighborhood Hits	112	Target Neighborhood Hits	95	Shared Neighborhood Hits	65
SwissProt Accessions	Q9UN37, Q8TF07, Q9UI03, Q9Y582	Gene names	VPS4A, VPS4
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associating protein 4A (SKD2 protein) (hVPS4) (VPS4-1).

VPS4A_MOUSE
θ value	3.27365e-34 (rank : 41)	NC score	0.907515 (rank : 38)
Query Neighborhood Hits	112	Target Neighborhood Hits	94	Shared Neighborhood Hits	65
SwissProt Accessions	Q8VEJ9, Q3TXT2	Gene names	Vps4a
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associating protein 4A.

FIGN_MOUSE
θ value	2.51237e-26 (rank : 42)	NC score	0.865628 (rank : 42)
Query Neighborhood Hits	112	Target Neighborhood Hits	165	Shared Neighborhood Hits	55
SwissProt Accessions	Q9ERZ6, Q3TPB0, Q3UP57, Q6PCM0	Gene names	Fign
Domain Architecture	No domain graphic available
Description	Fidgetin.

FIGN_HUMAN
θ value	1.24688e-25 (rank : 43)	NC score	0.860138 (rank : 43)
Query Neighborhood Hits	112	Target Neighborhood Hits	176	Shared Neighborhood Hits	55
SwissProt Accessions	Q5HY92, Q9H6M5, Q9NVZ9	Gene names	FIGN
Domain Architecture	No domain graphic available
Description	Fidgetin.

BCS1_HUMAN
θ value	4.59992e-12 (rank : 44)	NC score	0.703664 (rank : 46)
Query Neighborhood Hits	112	Target Neighborhood Hits	61	Shared Neighborhood Hits	54
SwissProt Accessions	Q9Y276, Q7Z2V7	Gene names	BCS1L, BCS1
Domain Architecture
Description	Mitochondrial chaperone BCS1 (BCS1-like protein) (H-BCS1).

BCS1_MOUSE
θ value	1.33837e-11 (rank : 45)	NC score	0.692098 (rank : 47)
Query Neighborhood Hits	112	Target Neighborhood Hits	64	Shared Neighborhood Hits	54
SwissProt Accessions	Q9CZP5	Gene names	Bcs1l
Domain Architecture
Description	Mitochondrial chaperone BCS1 (BCS1-like protein).

TRP13_MOUSE
θ value	1.33837e-11 (rank : 46)	NC score	0.732146 (rank : 44)
Query Neighborhood Hits	112	Target Neighborhood Hits	81	Shared Neighborhood Hits	63
SwissProt Accessions	Q3UA06, Q3UQG6, Q9CWW8	Gene names	Trip13
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 13 (Thyroid hormone receptor interactor 13) (Trip-13).

TRP13_HUMAN
θ value	1.9326e-10 (rank : 47)	NC score	0.726989 (rank : 45)
Query Neighborhood Hits	112	Target Neighborhood Hits	81	Shared Neighborhood Hits	64
SwissProt Accessions	Q15645, O15324	Gene names	TRIP13
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 13 (Thyroid hormone receptor interactor 13) (Trip-13) (Human papillomavirus type 16 E1 protein- binding protein) (HPV16 E1 protein-binding protein) (16E1-BP).

ATAD3_MOUSE
θ value	2.79066e-09 (rank : 48)	NC score	0.611102 (rank : 50)
Query Neighborhood Hits	112	Target Neighborhood Hits	326	Shared Neighborhood Hits	66
SwissProt Accessions	Q925I1, Q3UE74, Q69ZM7, Q8C6C6	Gene names	Atad3, Atad3a, Kiaa1273
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 3 (AAA-ATPase TOB3).

ATD3B_HUMAN
θ value	2.36244e-08 (rank : 49)	NC score	0.615310 (rank : 49)
Query Neighborhood Hits	112	Target Neighborhood Hits	340	Shared Neighborhood Hits	65
SwissProt Accessions	Q5T9A4, Q6ZRB5, Q9BUK4, Q9ULE7	Gene names	ATAD3B, KIAA1273
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 3B.

ATD3A_HUMAN
θ value	8.97725e-08 (rank : 50)	NC score	0.626188 (rank : 48)
Query Neighborhood Hits	112	Target Neighborhood Hits	248	Shared Neighborhood Hits	66
SwissProt Accessions	Q9NVI7, Q8N275, Q96A50	Gene names	ATAD3A
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 3A.

RUVB1_HUMAN
θ value	0.00175202 (rank : 51)	NC score	0.351195 (rank : 54)
Query Neighborhood Hits	112	Target Neighborhood Hits	78	Shared Neighborhood Hits	65
SwissProt Accessions	Q9Y265, Q9BSX9	Gene names	RUVBL1, NMP238, TIP49, TIP49A
Domain Architecture
Description	RuvB-like 1 (EC 3.6.1.-) (49 kDa TATA box-binding protein-interacting protein) (49 kDa TBP-interacting protein) (TIP49a) (Pontin 52) (Nuclear matrix protein 238) (NMP 238) (54 kDa erythrocyte cytosolic protein) (ECP-54) (TIP60-associated protein 54-alpha) (TAP54-alpha).

RUVB1_MOUSE
θ value	0.00175202 (rank : 52)	NC score	0.351158 (rank : 55)
Query Neighborhood Hits	112	Target Neighborhood Hits	78	Shared Neighborhood Hits	65
SwissProt Accessions	P60122, O35753	Gene names	Ruvbl1, Tip49, Tip49a
Domain Architecture
Description	RuvB-like 1 (EC 3.6.1.-) (49 kDa TATA box-binding protein-interacting protein) (49 kDa TBP-interacting protein) (TIP49a) (Pontin 52) (DNA helicase p50).

WRIP1_MOUSE
θ value	0.00509761 (rank : 53)	NC score	0.267224 (rank : 56)
Query Neighborhood Hits	112	Target Neighborhood Hits	93	Shared Neighborhood Hits	57
SwissProt Accessions	Q91XU0, Q3TCT7, Q6PDF0, Q8BUW5, Q8BWP6, Q8BY55, Q921W3, Q9EQL3	Gene names	Wrnip1, Whip
Domain Architecture	No domain graphic available
Description	ATPase WRNIP1 (Werner helicase-interacting protein 1).

WRIP1_HUMAN
θ value	0.00665767 (rank : 54)	NC score	0.263251 (rank : 57)
Query Neighborhood Hits	112	Target Neighborhood Hits	100	Shared Neighborhood Hits	56
SwissProt Accessions	Q96S55, Q53EP6, Q59ET8, Q5W0E2, Q5W0E4, Q8WV26, Q9H681, Q9NRJ6	Gene names	WRNIP1, WHIP
Domain Architecture	No domain graphic available
Description	ATPase WRNIP1 (Werner helicase-interacting protein 1).

CLPX_HUMAN
θ value	0.0113563 (rank : 55)	NC score	0.421137 (rank : 52)
Query Neighborhood Hits	112	Target Neighborhood Hits	72	Shared Neighborhood Hits	54
SwissProt Accessions	O76031, Q9H4D9	Gene names	CLPX
Domain Architecture
Description	ATP-dependent Clp protease ATP-binding subunit ClpX-like, mitochondrial precursor.

CLPX_MOUSE
θ value	0.0113563 (rank : 56)	NC score	0.418844 (rank : 53)
Query Neighborhood Hits	112	Target Neighborhood Hits	73	Shared Neighborhood Hits	54
SwissProt Accessions	Q9JHS4, Q9WVD1	Gene names	Clpx
Domain Architecture
Description	ATP-dependent Clp protease ATP-binding subunit ClpX-like, mitochondrial precursor.

RUVB2_HUMAN
θ value	0.0113563 (rank : 57)	NC score	0.165749 (rank : 58)
Query Neighborhood Hits	112	Target Neighborhood Hits	43	Shared Neighborhood Hits	41
SwissProt Accessions	Q9Y230, Q6PK27, Q9Y361	Gene names	RUVBL2, TIP48, TIP49B
Domain Architecture
Description	RuvB-like 2 (EC 3.6.1.-) (48 kDa TATA box-binding protein-interacting protein) (48 kDa TBP-interacting protein) (TIP49b) (Repressing pontin 52) (Reptin 52) (51 kDa erythrocyte cytosolic protein) (ECP-51) (TIP60-associated protein 54-beta) (TAP54-beta).

RUVB2_MOUSE
θ value	0.0113563 (rank : 58)	NC score	0.163084 (rank : 59)
Query Neighborhood Hits	112	Target Neighborhood Hits	42	Shared Neighborhood Hits	40
SwissProt Accessions	Q9WTM5	Gene names	Ruvbl2
Domain Architecture
Description	RuvB-like 2 (EC 3.6.1.-) (p47 protein).

OXR1_MOUSE
θ value	0.0252991 (rank : 59)	NC score	0.022301 (rank : 77)
Query Neighborhood Hits	112	Target Neighborhood Hits	516	Shared Neighborhood Hits	9
SwissProt Accessions	Q4KMM3, Q5FWW1, Q99L06, Q99MK1, Q99MP4	Gene names	Oxr1, C7
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1 (Protein C7).

KAD6_HUMAN
θ value	0.0563607 (rank : 60)	NC score	0.144292 (rank : 60)
Query Neighborhood Hits	112	Target Neighborhood Hits	46	Shared Neighborhood Hits	29
SwissProt Accessions	Q9Y3D8	Gene names	AK6
Domain Architecture
Description	Adenylate kinase isoenzyme 6 (EC 2.7.4.3) (ATP-AMP transphosphorylase 6).

KAD6_MOUSE
θ value	0.0961366 (rank : 61)	NC score	0.122743 (rank : 65)
Query Neighborhood Hits	112	Target Neighborhood Hits	34	Shared Neighborhood Hits	23
SwissProt Accessions	Q8VCP8	Gene names	Ak6
Domain Architecture	No domain graphic available
Description	Adenylate kinase isoenzyme 6 (EC 2.7.4.3) (ATP-AMP transphosphorylase 6).

LONM_HUMAN
θ value	0.0961366 (rank : 62)	NC score	0.430263 (rank : 51)
Query Neighborhood Hits	112	Target Neighborhood Hits	130	Shared Neighborhood Hits	64
SwissProt Accessions	P36776, P36777, Q9UQ95	Gene names	PRSS15
Domain Architecture
Description	Lon protease homolog, mitochondrial precursor (EC 3.4.21.-) (Lon protease-like protein) (LONP) (LONHs).

MDN1_HUMAN
θ value	0.163984 (rank : 63)	NC score	0.056829 (rank : 73)
Query Neighborhood Hits	112	Target Neighborhood Hits	662	Shared Neighborhood Hits	36
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

RFC2_HUMAN
θ value	0.163984 (rank : 64)	NC score	0.075810 (rank : 71)
Query Neighborhood Hits	112	Target Neighborhood Hits	46	Shared Neighborhood Hits	27
SwissProt Accessions	P35250, P32846, Q9BU93	Gene names	RFC2
Domain Architecture
Description	Replication factor C subunit 2 (Replication factor C 40 kDa subunit) (RF-C 40 kDa subunit) (RFC40) (Activator 1 40 kDa subunit) (A1 40 kDa subunit).

MRP3_HUMAN
θ value	0.279714 (rank : 65)	NC score	0.015536 (rank : 82)
Query Neighborhood Hits	112	Target Neighborhood Hits	125	Shared Neighborhood Hits	12
SwissProt Accessions	O15438, O60265, O60922, O75621, O95078, O95289, O95290, Q9UN52	Gene names	ABCC3, CMOAT2, MLP2, MRP3
Domain Architecture
Description	Canalicular multispecific organic anion transporter 2 (ATP-binding cassette sub-family C member 3) (Multidrug resistance-associated protein 3) (Multi-specific organic anion transporter-D) (MOAT-D).

RFC2_MOUSE
θ value	0.279714 (rank : 66)	NC score	0.072792 (rank : 72)
Query Neighborhood Hits	112	Target Neighborhood Hits	46	Shared Neighborhood Hits	27
SwissProt Accessions	Q9WUK4	Gene names	Rfc2
Domain Architecture
Description	Replication factor C subunit 2 (Replication factor C 40 kDa subunit) (RF-C 40 kDa subunit) (RFC40) (Activator 1 40 kDa subunit) (A1 40 kDa subunit).

RFC4_HUMAN
θ value	0.365318 (rank : 67)	NC score	0.135026 (rank : 62)
Query Neighborhood Hits	112	Target Neighborhood Hits	64	Shared Neighborhood Hits	44
SwissProt Accessions	P35249, Q6FHX7	Gene names	RFC4
Domain Architecture
Description	Replication factor C subunit 4 (Replication factor C 37 kDa subunit) (RF-C 37 kDa subunit) (RFC37) (Activator 1 37 kDa subunit) (A1 37 kDa subunit).

RFC4_MOUSE
θ value	0.365318 (rank : 68)	NC score	0.123347 (rank : 64)
Query Neighborhood Hits	112	Target Neighborhood Hits	65	Shared Neighborhood Hits	44
SwissProt Accessions	Q99J62	Gene names	Rfc4
Domain Architecture	No domain graphic available
Description	Replication factor C subunit 4.

IWS1_MOUSE
θ value	0.47712 (rank : 69)	NC score	0.017442 (rank : 80)
Query Neighborhood Hits	112	Target Neighborhood Hits	1258	Shared Neighborhood Hits	15
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

AQR_HUMAN
θ value	0.62314 (rank : 70)	NC score	0.044220 (rank : 76)
Query Neighborhood Hits	112	Target Neighborhood Hits	88	Shared Neighborhood Hits	14
SwissProt Accessions	O60306, Q2YDX9, Q6IRU8, Q6PIC8	Gene names	AQR, KIAA0560
Domain Architecture	No domain graphic available
Description	Intron-binding protein aquarius (Intron-binding protein of 160 kDa) (IBP160).

AQR_MOUSE
θ value	0.62314 (rank : 71)	NC score	0.045391 (rank : 75)
Query Neighborhood Hits	112	Target Neighborhood Hits	62	Shared Neighborhood Hits	14
SwissProt Accessions	Q8CFQ3, P97871, Q3U9N1, Q3ULE8, Q80TX8	Gene names	Aqr, Kiaa0560
Domain Architecture	No domain graphic available
Description	Intron-binding protein aquarius.

FOXO1_MOUSE
θ value	0.62314 (rank : 72)	NC score	0.011344 (rank : 86)
Query Neighborhood Hits	112	Target Neighborhood Hits	118	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R1E0	Gene names	Foxo1a, Fkhr, Foxo1
Domain Architecture
Description	Forkhead box protein O1A (Forkhead in rhabdomyosarcoma).

RFC1_MOUSE
θ value	0.62314 (rank : 73)	NC score	0.141742 (rank : 61)
Query Neighborhood Hits	112	Target Neighborhood Hits	290	Shared Neighborhood Hits	58
SwissProt Accessions	P35601	Gene names	Rfc1, Ibf-1, Recc1
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (A1-P145) (Differentiation- specific element-binding protein) (ISRE-binding protein).

ATRX_MOUSE
θ value	0.813845 (rank : 74)	NC score	0.010107 (rank : 94)
Query Neighborhood Hits	112	Target Neighborhood Hits	682	Shared Neighborhood Hits	11
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

IWS1_HUMAN
θ value	0.813845 (rank : 75)	NC score	0.011580 (rank : 85)
Query Neighborhood Hits	112	Target Neighborhood Hits	1241	Shared Neighborhood Hits	13
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

MRP6_MOUSE
θ value	0.813845 (rank : 76)	NC score	0.010577 (rank : 90)
Query Neighborhood Hits	112	Target Neighborhood Hits	105	Shared Neighborhood Hits	5
SwissProt Accessions	Q9R1S7, Q80YB6	Gene names	Abcc6, Mrp6
Domain Architecture	No domain graphic available
Description	Multidrug resistance-associated protein 6 (ATP-binding cassette sub- family C member 6).

RAD17_HUMAN
θ value	1.06291 (rank : 77)	NC score	0.055546 (rank : 74)
Query Neighborhood Hits	112	Target Neighborhood Hits	44	Shared Neighborhood Hits	18
SwissProt Accessions	O75943, O75714, Q7Z3S4, Q9UNK7, Q9UNR7, Q9UNR8, Q9UPF5	Gene names	RAD17, R24L
Domain Architecture	No domain graphic available
Description	Cell cycle checkpoint protein RAD17 (hRad17) (RF-C/activator 1 homolog).

FOXO1_HUMAN
θ value	1.38821 (rank : 78)	NC score	0.010163 (rank : 93)
Query Neighborhood Hits	112	Target Neighborhood Hits	126	Shared Neighborhood Hits	3
SwissProt Accessions	Q12778, O43523, Q5VYC7, Q6NSK6	Gene names	FOXO1A, FKHR
Domain Architecture
Description	Forkhead box protein O1A (Forkhead in rhabdomyosarcoma).

RAD17_MOUSE
θ value	1.38821 (rank : 79)	NC score	0.076660 (rank : 70)
Query Neighborhood Hits	112	Target Neighborhood Hits	63	Shared Neighborhood Hits	29
SwissProt Accessions	Q6NXW6, O88934, O89024	Gene names	Rad17
Domain Architecture	No domain graphic available
Description	Cell cycle checkpoint protein RAD17.

RFC1_HUMAN
θ value	1.38821 (rank : 80)	NC score	0.126083 (rank : 63)
Query Neighborhood Hits	112	Target Neighborhood Hits	352	Shared Neighborhood Hits	52
SwissProt Accessions	P35251, Q5XKF5, Q6PKU0, Q86V41, Q86V46	Gene names	RFC1, RFC140
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (DNA-binding protein PO-GA).

EXOC4_MOUSE
θ value	1.81305 (rank : 81)	NC score	0.017579 (rank : 79)
Query Neighborhood Hits	112	Target Neighborhood Hits	86	Shared Neighborhood Hits	4
SwissProt Accessions	O35382	Gene names	Exoc4, Sec8, Sec8l1
Domain Architecture
Description	Exocyst complex component 4 (Exocyst complex component Sec8).

NEBU_HUMAN
θ value	1.81305 (rank : 82)	NC score	0.007039 (rank : 101)
Query Neighborhood Hits	112	Target Neighborhood Hits	420	Shared Neighborhood Hits	4
SwissProt Accessions	P20929, Q15346	Gene names	NEB
Domain Architecture
Description	Nebulin.

MYO9B_HUMAN
θ value	2.36792 (rank : 83)	NC score	0.000375 (rank : 110)
Query Neighborhood Hits	112	Target Neighborhood Hits	641	Shared Neighborhood Hits	6
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

NOS1_HUMAN
θ value	2.36792 (rank : 84)	NC score	0.006117 (rank : 103)
Query Neighborhood Hits	112	Target Neighborhood Hits	218	Shared Neighborhood Hits	3
SwissProt Accessions	P29475	Gene names	NOS1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

PACE1_HUMAN
θ value	2.36792 (rank : 85)	NC score	0.010215 (rank : 92)
Query Neighborhood Hits	112	Target Neighborhood Hits	74	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IZE3, Q5THA6, Q5THA8, Q8IZN9, Q96C56, Q9UBK6	Gene names	SCYL3, PACE1
Domain Architecture	No domain graphic available
Description	Protein-associating with the carboxyl-terminal domain of ezrin (Ezrin- binding protein PACE-1) (SCY1-like protein 3).

PHF8_HUMAN
θ value	2.36792 (rank : 86)	NC score	0.005920 (rank : 104)
Query Neighborhood Hits	112	Target Neighborhood Hits	105	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UPP1, Q5H9U5, Q5VUJ4, Q7Z6D4, Q9HAH2	Gene names	PHF8, KIAA1111, ZNF422
Domain Architecture	No domain graphic available
Description	PHD finger protein 8.

ANR18_HUMAN
θ value	3.0926 (rank : 87)	NC score	-0.000545 (rank : 111)
Query Neighborhood Hits	112	Target Neighborhood Hits	1106	Shared Neighborhood Hits	13
SwissProt Accessions	Q8IVF6, Q7Z468	Gene names	ANKRD18A, KIAA2015
Domain Architecture
Description	Ankyrin repeat domain-containing protein 18A.

PHAR3_HUMAN
θ value	3.0926 (rank : 88)	NC score	0.010584 (rank : 89)
Query Neighborhood Hits	112	Target Neighborhood Hits	169	Shared Neighborhood Hits	4
SwissProt Accessions	Q96KR7, Q707P6, Q9H4T4	Gene names	PHACTR3, C20orf101, SCAPIN1
Domain Architecture	No domain graphic available
Description	Phosphatase and actin regulator 3 (Scapinin) (Scaffold-associated PP1- inhibiting protein).

CE290_HUMAN
θ value	4.03905 (rank : 89)	NC score	0.004745 (rank : 106)
Query Neighborhood Hits	112	Target Neighborhood Hits	1553	Shared Neighborhood Hits	16
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

MRP6_HUMAN
θ value	4.03905 (rank : 90)	NC score	0.012684 (rank : 84)
Query Neighborhood Hits	112	Target Neighborhood Hits	113	Shared Neighborhood Hits	9
SwissProt Accessions	O95255, P78420, Q9UMZ7	Gene names	ABCC6, ARA, MRP6
Domain Architecture
Description	Multidrug resistance-associated protein 6 (ATP-binding cassette sub- family C member 6) (Anthracycline resistance-associated protein) (Multi-specific organic anion transporter-E) (MOAT-E).

PCDG2_HUMAN
θ value	4.03905 (rank : 91)	NC score	-0.001143 (rank : 112)
Query Neighborhood Hits	112	Target Neighborhood Hits	151	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y5H1, Q9Y5D5	Gene names	PCDHGA2
Domain Architecture
Description	Protocadherin gamma A2 precursor (PCDH-gamma-A2).

PI51C_HUMAN
θ value	4.03905 (rank : 92)	NC score	0.008034 (rank : 100)
Query Neighborhood Hits	112	Target Neighborhood Hits	109	Shared Neighborhood Hits	6
SwissProt Accessions	O60331, Q7LE07	Gene names	PIP5K1C, KIAA0589
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type I gamma) (PtdIns(4)P- 5-kinase gamma) (PtdInsPKIgamma) (PIP5KIgamma).

SACS_MOUSE
θ value	4.03905 (rank : 93)	NC score	0.011015 (rank : 88)
Query Neighborhood Hits	112	Target Neighborhood Hits	99	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JLC8	Gene names	Sacs
Domain Architecture
Description	Sacsin.

MOV10_HUMAN
θ value	5.27518 (rank : 94)	NC score	0.019637 (rank : 78)
Query Neighborhood Hits	112	Target Neighborhood Hits	46	Shared Neighborhood Hits	16
SwissProt Accessions	Q9HCE1, Q8TEF0, Q9BSY3, Q9BUJ9	Gene names	MOV10, KIAA1631
Domain Architecture
Description	Putative helicase MOV-10 (EC 3.6.1.-) (Moloney leukemia virus 10 protein).

MOV10_MOUSE
θ value	5.27518 (rank : 95)	NC score	0.015520 (rank : 83)
Query Neighborhood Hits	112	Target Neighborhood Hits	39	Shared Neighborhood Hits	15
SwissProt Accessions	P23249, Q9DC64	Gene names	Mov10, Gb110
Domain Architecture
Description	Putative helicase MOV-10 (EC 3.6.1.-) (Moloney leukemia virus 10 protein).

DYHC_HUMAN
θ value	6.88961 (rank : 96)	NC score	0.008730 (rank : 96)
Query Neighborhood Hits	112	Target Neighborhood Hits	733	Shared Neighborhood Hits	17
SwissProt Accessions	Q14204, Q6DKQ7, Q8WU28, Q92814, Q9Y4G5	Gene names	DYNC1H1, DNCH1, DNECL, KIAA0325
Domain Architecture	No domain graphic available
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

DYHC_MOUSE
θ value	6.88961 (rank : 97)	NC score	0.008737 (rank : 95)
Query Neighborhood Hits	112	Target Neighborhood Hits	729	Shared Neighborhood Hits	17
SwissProt Accessions	Q9JHU4	Gene names	Dync1h1, Dnch1, Dnchc1
Domain Architecture
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

NALP5_MOUSE
θ value	6.88961 (rank : 98)	NC score	0.010471 (rank : 91)
Query Neighborhood Hits	112	Target Neighborhood Hits	560	Shared Neighborhood Hits	17
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

PHAR3_MOUSE
θ value	6.88961 (rank : 99)	NC score	0.008249 (rank : 99)
Query Neighborhood Hits	112	Target Neighborhood Hits	206	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BYK5, Q8BYS8, Q8C058, Q9DB87	Gene names	Phactr3, Scapin1
Domain Architecture	No domain graphic available
Description	Phosphatase and actin regulator 3 (Scapinin) (Scaffold-associated PP1- inhibiting protein).

PI51C_MOUSE
θ value	6.88961 (rank : 100)	NC score	0.006453 (rank : 102)
Query Neighborhood Hits	112	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	O70161, Q505A1, Q80TW9, Q8VCU5	Gene names	Pip5k1c, Kiaa0589
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type I gamma) (PtdIns(4)P- 5-kinase gamma) (PtdInsPKIgamma) (PIP5KIgamma).

S29A3_HUMAN
θ value	6.88961 (rank : 101)	NC score	0.008520 (rank : 98)
Query Neighborhood Hits	112	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BZD2, Q7RTT8, Q8IVZ0	Gene names	SLC29A3, ENT3
Domain Architecture
Description	Equilibrative nucleoside transporter 3 (Solute carrier family 29 member 3).

THNSL_HUMAN
θ value	6.88961 (rank : 102)	NC score	0.105989 (rank : 67)
Query Neighborhood Hits	112	Target Neighborhood Hits	47	Shared Neighborhood Hits	38
SwissProt Accessions	Q8IYQ7, Q5VV21	Gene names	THNSL1
Domain Architecture	No domain graphic available
Description	Threonine synthase-like 1.

THNSL_MOUSE
θ value	6.88961 (rank : 103)	NC score	0.109294 (rank : 66)
Query Neighborhood Hits	112	Target Neighborhood Hits	47	Shared Neighborhood Hits	37
SwissProt Accessions	Q8BH55	Gene names	Thnsl1
Domain Architecture	No domain graphic available
Description	Threonine synthase-like 1.

AT2A2_HUMAN
θ value	8.99809 (rank : 104)	NC score	0.001550 (rank : 108)
Query Neighborhood Hits	112	Target Neighborhood Hits	66	Shared Neighborhood Hits	3
SwissProt Accessions	P16615, P16614	Gene names	ATP2A2, ATP2B
Domain Architecture
Description	Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (EC 3.6.3.8) (Calcium pump 2) (SERCA2) (SR Ca(2+)-ATPase 2) (Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform) (Endoplasmic reticulum class 1/2 Ca(2+) ATPase).

AT2A2_MOUSE
θ value	8.99809 (rank : 105)	NC score	0.001542 (rank : 109)
Query Neighborhood Hits	112	Target Neighborhood Hits	68	Shared Neighborhood Hits	3
SwissProt Accessions	O55143, Q9R2A9, Q9WUT5	Gene names	Atp2a2
Domain Architecture
Description	Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (EC 3.6.3.8) (Calcium pump 2) (SERCA2) (SR Ca(2+)-ATPase 2) (Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform) (Endoplasmic reticulum class 1/2 Ca(2+) ATPase).

CLPB_HUMAN
θ value	8.99809 (rank : 106)	NC score	0.011099 (rank : 87)
Query Neighborhood Hits	112	Target Neighborhood Hits	265	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H078, Q8ND11, Q9H8Y0	Gene names	CLPB, SKD3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

CLPB_MOUSE
θ value	8.99809 (rank : 107)	NC score	0.008559 (rank : 97)
Query Neighborhood Hits	112	Target Neighborhood Hits	289	Shared Neighborhood Hits	7
SwissProt Accessions	Q60649	Gene names	Clpb, Skd3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

KIF4A_MOUSE
θ value	8.99809 (rank : 108)	NC score	-0.002372 (rank : 113)
Query Neighborhood Hits	112	Target Neighborhood Hits	1033	Shared Neighborhood Hits	8
SwissProt Accessions	P33174	Gene names	Kif4a, Kif4, Kns4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

NAL12_HUMAN
θ value	8.99809 (rank : 109)	NC score	0.004252 (rank : 107)
Query Neighborhood Hits	112	Target Neighborhood Hits	96	Shared Neighborhood Hits	5
SwissProt Accessions	P59046, Q8NEU4, Q9BY26	Gene names	NALP12, PYPAF7, RNO
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 12 (PYRIN-containing APAF1-like protein 7) (Monarch-1) (Regulated by nitric oxide).

NALP7_HUMAN
θ value	8.99809 (rank : 110)	NC score	0.016579 (rank : 81)
Query Neighborhood Hits	112	Target Neighborhood Hits	65	Shared Neighborhood Hits	14
SwissProt Accessions	Q8WX94, Q7RTR1	Gene names	NALP7, NOD12, PYPAF3
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 7 (PYRIN-containing APAF1-like protein 3).

NOS1_MOUSE
θ value	8.99809 (rank : 111)	NC score	0.004907 (rank : 105)
Query Neighborhood Hits	112	Target Neighborhood Hits	155	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z0J4, Q64208	Gene names	Nos1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

ZN710_HUMAN
θ value	8.99809 (rank : 112)	NC score	-0.005984 (rank : 114)
Query Neighborhood Hits	112	Target Neighborhood Hits	796	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N1W2, Q6ZMK9, Q8NDU0	Gene names	ZNF710
Domain Architecture	No domain graphic available
Description	Zinc finger protein 710.

RFC5_HUMAN
θ value	θ > 10 (rank : 113)	NC score	0.084220 (rank : 69)
Query Neighborhood Hits	112	Target Neighborhood Hits	60	Shared Neighborhood Hits	36
SwissProt Accessions	P40937	Gene names	RFC5
Domain Architecture
Description	Replication factor C subunit 5 (Replication factor C 36 kDa subunit) (RF-C 36 kDa subunit) (RFC36) (Activator 1 36 kDa subunit) (A1 36 kDa subunit).

RFC5_MOUSE
θ value	θ > 10 (rank : 114)	NC score	0.084997 (rank : 68)
Query Neighborhood Hits	112	Target Neighborhood Hits	58	Shared Neighborhood Hits	40
SwissProt Accessions	Q9D0F6	Gene names	Rfc5
Domain Architecture
Description	Replication factor C subunit 5 (Replication factor C 36 kDa subunit) (RF-C 36 kDa subunit) (RFC36) (Activator 1 36 kDa subunit) (A1 36 kDa subunit).

Hits sorted by NC score

NVL_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	112	Target Neighborhood Hits	112	Shared Neighborhood Hits	112
SwissProt Accessions	O15381, Q96EM7	Gene names	NVL
Domain Architecture
Description	Nuclear valosin-containing protein-like (Nuclear VCP-like protein) (NVLp).

NVL_MOUSE
NC score	0.997992 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	112	Target Neighborhood Hits	110	Shared Neighborhood Hits	86
SwissProt Accessions	Q9DBY8, Q3USC4, Q8BW27, Q8K2B5	Gene names	Nvl
Domain Architecture
Description	Nuclear valosin-containing protein-like (Nuclear VCP-like protein) (NVLp).

TERA_MOUSE
NC score	0.982065 (rank : 3)	θ value	2.35568e-133 (rank : 3)
Query Neighborhood Hits	112	Target Neighborhood Hits	76	Shared Neighborhood Hits	69
SwissProt Accessions	Q01853	Gene names	Vcp
Domain Architecture
Description	Transitional endoplasmic reticulum ATPase (TER ATPase) (15S Mg(2+)- ATPase p97 subunit) (Valosin-containing protein) (VCP).

TERA_HUMAN
NC score	0.982049 (rank : 4)	θ value	3.07662e-133 (rank : 4)
Query Neighborhood Hits	112	Target Neighborhood Hits	76	Shared Neighborhood Hits	69
SwissProt Accessions	P55072, Q969G7	Gene names	VCP
Domain Architecture
Description	Transitional endoplasmic reticulum ATPase (TER ATPase) (15S Mg(2+)- ATPase p97 subunit) (Valosin-containing protein) (VCP).

PEX6_HUMAN
NC score	0.959834 (rank : 5)	θ value	3.69378e-78 (rank : 5)
Query Neighborhood Hits	112	Target Neighborhood Hits	99	Shared Neighborhood Hits	73
SwissProt Accessions	Q13608, Q8WYQ2, Q99476	Gene names	PEX6, PXAAA1
Domain Architecture
Description	Peroxisome assembly factor 2 (PAF-2) (Peroxisomal-type ATPase 1) (Peroxin-6) (Peroxisomal biogenesis factor 6).

PEX6_MOUSE
NC score	0.959120 (rank : 6)	θ value	1.18825e-76 (rank : 6)
Query Neighborhood Hits	112	Target Neighborhood Hits	94	Shared Neighborhood Hits	71
SwissProt Accessions	Q99LC9, Q6YNQ9	Gene names	Pex6
Domain Architecture	No domain graphic available
Description	Peroxisome assembly factor 2 (PAF-2) (Peroxisomal-type ATPase 1) (Peroxin-6) (Peroxisomal biogenesis factor 6).

PEX1_HUMAN
NC score	0.957210 (rank : 7)	θ value	4.10295e-61 (rank : 7)
Query Neighborhood Hits	112	Target Neighborhood Hits	98	Shared Neighborhood Hits	64
SwissProt Accessions	O43933, Q96S71, Q96S72, Q96S73, Q99994	Gene names	PEX1
Domain Architecture
Description	Peroxisome biogenesis factor 1 (Peroxin-1) (Peroxisome biogenesis disorder protein 1).

PRS10_HUMAN
NC score	0.943408 (rank : 8)	θ value	1.56636e-44 (rank : 12)
Query Neighborhood Hits	112	Target Neighborhood Hits	95	Shared Neighborhood Hits	71
SwissProt Accessions	P62333, P49719, Q6IBU3, Q92524	Gene names	PSMC6, SUG2
Domain Architecture
Description	26S protease regulatory subunit S10B (Proteasome subunit p42) (Proteasome 26S subunit ATPase 6).

PRS10_MOUSE
NC score	0.943408 (rank : 9)	θ value	1.56636e-44 (rank : 13)
Query Neighborhood Hits	112	Target Neighborhood Hits	95	Shared Neighborhood Hits	71
SwissProt Accessions	P62334, P49719, Q3TKK1, Q810A6, Q92524, Q9CXH9	Gene names	Psmc6, Sug2
Domain Architecture
Description	26S protease regulatory subunit S10B (Proteasome subunit p42) (Proteasome 26S subunit ATPase 6).

PRS4_HUMAN
NC score	0.939983 (rank : 10)	θ value	4.2656e-42 (rank : 22)
Query Neighborhood Hits	112	Target Neighborhood Hits	84	Shared Neighborhood Hits	65
SwissProt Accessions	P62191, P49014, Q03527, Q6IAW0, Q96AZ3	Gene names	PSMC1
Domain Architecture
Description	26S protease regulatory subunit 4 (P26s4) (Proteasome 26S subunit ATPase 1).

PRS4_MOUSE
NC score	0.939983 (rank : 11)	θ value	4.2656e-42 (rank : 23)
Query Neighborhood Hits	112	Target Neighborhood Hits	84	Shared Neighborhood Hits	65
SwissProt Accessions	P62192, P49014, Q03527, Q96AZ3	Gene names	Psmc1
Domain Architecture
Description	26S protease regulatory subunit 4 (P26s4) (Proteasome 26S subunit ATPase 1).

PRS8_HUMAN
NC score	0.939766 (rank : 12)	θ value	3.61106e-41 (rank : 26)
Query Neighborhood Hits	112	Target Neighborhood Hits	117	Shared Neighborhood Hits	67
SwissProt Accessions	P62195, O35051, O43208, P47210, P52915, P52916	Gene names	PSMC5, SUG1
Domain Architecture
Description	26S protease regulatory subunit 8 (Proteasome 26S subunit ATPase 5) (Proteasome subunit p45) (p45/SUG) (Thyroid hormone receptor- interacting protein 1) (TRIP1).

PRS8_MOUSE
NC score	0.939766 (rank : 13)	θ value	3.61106e-41 (rank : 27)
Query Neighborhood Hits	112	Target Neighborhood Hits	117	Shared Neighborhood Hits	67
SwissProt Accessions	P62196, O35051, P47210, P52915, P52916, Q3UL51, Q9CWN5	Gene names	Psmc5, Sug1
Domain Architecture
Description	26S protease regulatory subunit 8 (Proteasome 26S subunit ATPase 5) (Proteasome subunit p45) (p45/SUG) (mSUG1).

PRS7_HUMAN
NC score	0.938969 (rank : 14)	θ value	7.77379e-44 (rank : 15)
Query Neighborhood Hits	112	Target Neighborhood Hits	66	Shared Neighborhood Hits	62
SwissProt Accessions	P35998	Gene names	PSMC2, MSS1
Domain Architecture
Description	26S protease regulatory subunit 7 (Proteasome 26S subunit ATPase 2) (Protein MSS1).

PRS7_MOUSE
NC score	0.938960 (rank : 15)	θ value	7.77379e-44 (rank : 16)
Query Neighborhood Hits	112	Target Neighborhood Hits	67	Shared Neighborhood Hits	62
SwissProt Accessions	P46471, O08531, Q3TGX5, Q9DBA1	Gene names	Psmc2, Mss1
Domain Architecture
Description	26S protease regulatory subunit 7 (Proteasome 26S subunit ATPase 2) (Protein MSS1).

PRS6B_HUMAN
NC score	0.938714 (rank : 16)	θ value	9.81109e-47 (rank : 8)
Query Neighborhood Hits	112	Target Neighborhood Hits	85	Shared Neighborhood Hits	59
SwissProt Accessions	P43686, Q96FV5, Q9UBM3, Q9UEX3	Gene names	PSMC4, TBP7
Domain Architecture
Description	26S protease regulatory subunit 6B (Proteasome 26S subunit ATPase 4) (MIP224) (MB67-interacting protein) (TAT-binding protein 7) (TBP-7).

PRS6B_MOUSE
NC score	0.938151 (rank : 17)	θ value	1.41672e-45 (rank : 9)
Query Neighborhood Hits	112	Target Neighborhood Hits	89	Shared Neighborhood Hits	59
SwissProt Accessions	P54775	Gene names	Psmc4, Tbp7
Domain Architecture
Description	26S protease regulatory subunit 6B (Proteasome 26S subunit ATPase 4) (MIP224) (MB67-interacting protein) (TAT-binding protein 7) (TBP-7) (CIP21).

PRS6A_MOUSE
NC score	0.937692 (rank : 18)	θ value	1.12253e-42 (rank : 19)
Query Neighborhood Hits	112	Target Neighborhood Hits	85	Shared Neighborhood Hits	61
SwissProt Accessions	O88685	Gene names	Psmc3, Tbp1
Domain Architecture
Description	26S protease regulatory subunit 6A (Proteasome 26S subunit ATPase 3) (TAT-binding protein 1) (TBP-1).

PRS6A_HUMAN
NC score	0.937594 (rank : 19)	θ value	8.59492e-43 (rank : 18)
Query Neighborhood Hits	112	Target Neighborhood Hits	87	Shared Neighborhood Hits	61
SwissProt Accessions	P17980, Q96HD3	Gene names	PSMC3, TBP1
Domain Architecture
Description	26S protease regulatory subunit 6A (Proteasome 26S subunit ATPase 3) (TAT-binding protein 1) (TBP-1) (Proteasome subunit P50).

ATAD1_HUMAN
NC score	0.932871 (rank : 20)	θ value	2.26708e-35 (rank : 35)
Query Neighborhood Hits	112	Target Neighborhood Hits	75	Shared Neighborhood Hits	67
SwissProt Accessions	Q8NBU5, Q6P4B9, Q8N3G1, Q8WYR9, Q969Y3	Gene names	ATAD1
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 1.

ATAD1_MOUSE
NC score	0.932871 (rank : 21)	θ value	2.26708e-35 (rank : 36)
Query Neighborhood Hits	112	Target Neighborhood Hits	75	Shared Neighborhood Hits	67
SwissProt Accessions	Q9D5T0, Q3U8V2, Q9D7A4	Gene names	Atad1
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 1.

SPG7_HUMAN
NC score	0.928117 (rank : 22)	θ value	5.57106e-42 (rank : 24)
Query Neighborhood Hits	112	Target Neighborhood Hits	71	Shared Neighborhood Hits	60
SwissProt Accessions	Q9UQ90, O75756, Q96IB0	Gene names	SPG7, CAR, CMAR, PGN
Domain Architecture
Description	Paraplegin (EC 3.4.24.-) (Spastic paraplegia protein 7).

AFG31_MOUSE
NC score	0.927585 (rank : 23)	θ value	7.03111e-45 (rank : 10)
Query Neighborhood Hits	112	Target Neighborhood Hits	74	Shared Neighborhood Hits	64
SwissProt Accessions	Q920A7	Gene names	Afg3l1
Domain Architecture
Description	AFG3-like protein 1 (EC 3.4.24.-).

KATL1_MOUSE
NC score	0.925337 (rank : 24)	θ value	7.27602e-42 (rank : 25)
Query Neighborhood Hits	112	Target Neighborhood Hits	77	Shared Neighborhood Hits	68
SwissProt Accessions	Q8K0T4	Gene names	Katnal1
Domain Architecture	No domain graphic available
Description	Katanin p60 ATPase-containing subunit A-like 1 (EC 3.6.4.3) (Katanin p60 subunit A-like 1) (p60 katanin-like 1).

KATL1_HUMAN
NC score	0.925111 (rank : 25)	θ value	3.26607e-42 (rank : 21)
Query Neighborhood Hits	112	Target Neighborhood Hits	80	Shared Neighborhood Hits	68
SwissProt Accessions	Q9BW62	Gene names	KATNAL1
Domain Architecture	No domain graphic available
Description	Katanin p60 ATPase-containing subunit A-like 1 (EC 3.6.4.3) (Katanin p60 subunit A-like 1) (p60 katanin-like 1).

AFG32_HUMAN
NC score	0.923986 (rank : 26)	θ value	1.19932e-44 (rank : 11)
Query Neighborhood Hits	112	Target Neighborhood Hits	72	Shared Neighborhood Hits	64
SwissProt Accessions	Q9Y4W6	Gene names	AFG3L2
Domain Architecture
Description	AFG3-like protein 2 (EC 3.4.24.-) (Paraplegin-like protein).

AFG32_MOUSE
NC score	0.923723 (rank : 27)	θ value	3.48949e-44 (rank : 14)
Query Neighborhood Hits	112	Target Neighborhood Hits	73	Shared Neighborhood Hits	64
SwissProt Accessions	Q8JZQ2	Gene names	Afg3l2
Domain Architecture	No domain graphic available
Description	AFG3-like protein 2 (EC 3.4.24.-).

YMEL1_MOUSE
NC score	0.921199 (rank : 28)	θ value	7.04741e-37 (rank : 31)
Query Neighborhood Hits	112	Target Neighborhood Hits	76	Shared Neighborhood Hits	62
SwissProt Accessions	O88967, Q7TNN5	Gene names	Yme1l1
Domain Architecture
Description	ATP-dependent metalloprotease YME1L1 (EC 3.4.24.-) (YME1-like protein 1) (ATP-dependent metalloprotease FtsH1).

KTNA1_HUMAN
NC score	0.919351 (rank : 29)	θ value	5.76516e-39 (rank : 28)
Query Neighborhood Hits	112	Target Neighborhood Hits	117	Shared Neighborhood Hits	66
SwissProt Accessions	O75449, Q5TFA8, Q5TFA9, Q86VN2, Q9NU52	Gene names	KATNA1
Domain Architecture	No domain graphic available
Description	Katanin p60 ATPase-containing subunit A1 (EC 3.6.4.3) (Katanin p60 subunit A1) (p60 katanin).

YMEL1_HUMAN
NC score	0.917961 (rank : 30)	θ value	2.42216e-37 (rank : 30)
Query Neighborhood Hits	112	Target Neighborhood Hits	73	Shared Neighborhood Hits	62
SwissProt Accessions	Q96TA2, Q9H1Q0, Q9UMR9	Gene names	YME1L1, FTSH1, YME1L
Domain Architecture
Description	ATP-dependent metalloprotease YME1L1 (EC 3.4.24.-) (YME1-like protein 1) (ATP-dependent metalloprotease FtsH1) (Meg-4) (Presenilin- associated metalloprotease) (PAMP).

KTNA1_MOUSE
NC score	0.917151 (rank : 31)	θ value	7.52953e-39 (rank : 29)
Query Neighborhood Hits	112	Target Neighborhood Hits	123	Shared Neighborhood Hits	66
SwissProt Accessions	Q9WV86	Gene names	Katna1
Domain Architecture	No domain graphic available
Description	Katanin p60 ATPase-containing subunit A1 (EC 3.6.4.3) (Katanin p60 subunit A1) (p60 katanin) (Lipotransin).

NSF_MOUSE
NC score	0.916492 (rank : 32)	θ value	6.59618e-35 (rank : 39)
Query Neighborhood Hits	112	Target Neighborhood Hits	73	Shared Neighborhood Hits	62
SwissProt Accessions	P46460	Gene names	Nsf, Skd2
Domain Architecture
Description	Vesicle-fusing ATPase (EC 3.6.4.6) (Vesicular-fusion protein NSF) (N- ethylmaleimide sensitive fusion protein) (NEM-sensitive fusion protein) (SKD2 protein).

NSF_HUMAN
NC score	0.916468 (rank : 33)	θ value	3.86705e-35 (rank : 38)
Query Neighborhood Hits	112	Target Neighborhood Hits	74	Shared Neighborhood Hits	65
SwissProt Accessions	P46459, Q9UKZ2	Gene names	NSF
Domain Architecture
Description	Vesicle-fusing ATPase (EC 3.6.4.6) (Vesicular-fusion protein NSF) (N- ethylmaleimide sensitive fusion protein) (NEM-sensitive fusion protein).

SPAST_HUMAN
NC score	0.914372 (rank : 34)	θ value	5.96599e-36 (rank : 33)
Query Neighborhood Hits	112	Target Neighborhood Hits	100	Shared Neighborhood Hits	62
SwissProt Accessions	Q9UBP0, Q9UPR9	Gene names	SPAST, KIAA1083, SPG4
Domain Architecture
Description	Spastin.

SPAST_MOUSE
NC score	0.913628 (rank : 35)	θ value	2.67802e-36 (rank : 32)
Query Neighborhood Hits	112	Target Neighborhood Hits	138	Shared Neighborhood Hits	65
SwissProt Accessions	Q9QYY8, Q6ZPY6, Q80VE0, Q9CVK0	Gene names	Spast, Kiaa1083, Spg4
Domain Architecture	No domain graphic available
Description	Spastin.

VPS4B_HUMAN
NC score	0.909752 (rank : 36)	θ value	5.96599e-36 (rank : 34)
Query Neighborhood Hits	112	Target Neighborhood Hits	87	Shared Neighborhood Hits	63
SwissProt Accessions	O75351, Q9GZS7	Gene names	VPS4B, SKD1, VPS42
Domain Architecture
Description	Vacuolar protein sorting-associating protein 4B (Protein SKD1).

VPS4B_MOUSE
NC score	0.908901 (rank : 37)	θ value	2.96089e-35 (rank : 37)
Query Neighborhood Hits	112	Target Neighborhood Hits	86	Shared Neighborhood Hits	64
SwissProt Accessions	P46467, Q91W22, Q9R1C9	Gene names	Vps4b, Skd1
Domain Architecture
Description	Vacuolar protein sorting-associating protein 4B (Protein SKD1).

VPS4A_MOUSE
NC score	0.907515 (rank : 38)	θ value	3.27365e-34 (rank : 41)
Query Neighborhood Hits	112	Target Neighborhood Hits	94	Shared Neighborhood Hits	65
SwissProt Accessions	Q8VEJ9, Q3TXT2	Gene names	Vps4a
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associating protein 4A.

VPS4A_HUMAN
NC score	0.907512 (rank : 39)	θ value	3.27365e-34 (rank : 40)
Query Neighborhood Hits	112	Target Neighborhood Hits	95	Shared Neighborhood Hits	65
SwissProt Accessions	Q9UN37, Q8TF07, Q9UI03, Q9Y582	Gene names	VPS4A, VPS4
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associating protein 4A (SKD2 protein) (hVPS4) (VPS4-1).

ATAD2_MOUSE
NC score	0.886130 (rank : 40)	θ value	6.58091e-43 (rank : 17)
Query Neighborhood Hits	112	Target Neighborhood Hits	167	Shared Neighborhood Hits	61
SwissProt Accessions	Q8CDM1	Gene names	Atad2
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 2.

ATAD2_HUMAN
NC score	0.869038 (rank : 41)	θ value	1.46607e-42 (rank : 20)
Query Neighborhood Hits	112	Target Neighborhood Hits	322	Shared Neighborhood Hits	66
SwissProt Accessions	Q6PL18, Q658P2, Q68CQ0, Q6PJV6, Q8N890, Q9UHS5	Gene names	ATAD2
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 2.

FIGN_MOUSE
NC score	0.865628 (rank : 42)	θ value	2.51237e-26 (rank : 42)
Query Neighborhood Hits	112	Target Neighborhood Hits	165	Shared Neighborhood Hits	55
SwissProt Accessions	Q9ERZ6, Q3TPB0, Q3UP57, Q6PCM0	Gene names	Fign
Domain Architecture	No domain graphic available
Description	Fidgetin.

FIGN_HUMAN
NC score	0.860138 (rank : 43)	θ value	1.24688e-25 (rank : 43)
Query Neighborhood Hits	112	Target Neighborhood Hits	176	Shared Neighborhood Hits	55
SwissProt Accessions	Q5HY92, Q9H6M5, Q9NVZ9	Gene names	FIGN
Domain Architecture	No domain graphic available
Description	Fidgetin.

TRP13_MOUSE
NC score	0.732146 (rank : 44)	θ value	1.33837e-11 (rank : 46)
Query Neighborhood Hits	112	Target Neighborhood Hits	81	Shared Neighborhood Hits	63
SwissProt Accessions	Q3UA06, Q3UQG6, Q9CWW8	Gene names	Trip13
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 13 (Thyroid hormone receptor interactor 13) (Trip-13).

TRP13_HUMAN
NC score	0.726989 (rank : 45)	θ value	1.9326e-10 (rank : 47)
Query Neighborhood Hits	112	Target Neighborhood Hits	81	Shared Neighborhood Hits	64
SwissProt Accessions	Q15645, O15324	Gene names	TRIP13
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 13 (Thyroid hormone receptor interactor 13) (Trip-13) (Human papillomavirus type 16 E1 protein- binding protein) (HPV16 E1 protein-binding protein) (16E1-BP).

BCS1_HUMAN
NC score	0.703664 (rank : 46)	θ value	4.59992e-12 (rank : 44)
Query Neighborhood Hits	112	Target Neighborhood Hits	61	Shared Neighborhood Hits	54
SwissProt Accessions	Q9Y276, Q7Z2V7	Gene names	BCS1L, BCS1
Domain Architecture
Description	Mitochondrial chaperone BCS1 (BCS1-like protein) (H-BCS1).

BCS1_MOUSE
NC score	0.692098 (rank : 47)	θ value	1.33837e-11 (rank : 45)
Query Neighborhood Hits	112	Target Neighborhood Hits	64	Shared Neighborhood Hits	54
SwissProt Accessions	Q9CZP5	Gene names	Bcs1l
Domain Architecture
Description	Mitochondrial chaperone BCS1 (BCS1-like protein).

ATD3A_HUMAN
NC score	0.626188 (rank : 48)	θ value	8.97725e-08 (rank : 50)
Query Neighborhood Hits	112	Target Neighborhood Hits	248	Shared Neighborhood Hits	66
SwissProt Accessions	Q9NVI7, Q8N275, Q96A50	Gene names	ATAD3A
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 3A.

ATD3B_HUMAN
NC score	0.615310 (rank : 49)	θ value	2.36244e-08 (rank : 49)
Query Neighborhood Hits	112	Target Neighborhood Hits	340	Shared Neighborhood Hits	65
SwissProt Accessions	Q5T9A4, Q6ZRB5, Q9BUK4, Q9ULE7	Gene names	ATAD3B, KIAA1273
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 3B.

ATAD3_MOUSE
NC score	0.611102 (rank : 50)	θ value	2.79066e-09 (rank : 48)
Query Neighborhood Hits	112	Target Neighborhood Hits	326	Shared Neighborhood Hits	66
SwissProt Accessions	Q925I1, Q3UE74, Q69ZM7, Q8C6C6	Gene names	Atad3, Atad3a, Kiaa1273
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 3 (AAA-ATPase TOB3).

LONM_HUMAN
NC score	0.430263 (rank : 51)	θ value	0.0961366 (rank : 62)
Query Neighborhood Hits	112	Target Neighborhood Hits	130	Shared Neighborhood Hits	64
SwissProt Accessions	P36776, P36777, Q9UQ95	Gene names	PRSS15
Domain Architecture
Description	Lon protease homolog, mitochondrial precursor (EC 3.4.21.-) (Lon protease-like protein) (LONP) (LONHs).

CLPX_HUMAN
NC score	0.421137 (rank : 52)	θ value	0.0113563 (rank : 55)
Query Neighborhood Hits	112	Target Neighborhood Hits	72	Shared Neighborhood Hits	54
SwissProt Accessions	O76031, Q9H4D9	Gene names	CLPX
Domain Architecture
Description	ATP-dependent Clp protease ATP-binding subunit ClpX-like, mitochondrial precursor.

CLPX_MOUSE
NC score	0.418844 (rank : 53)	θ value	0.0113563 (rank : 56)
Query Neighborhood Hits	112	Target Neighborhood Hits	73	Shared Neighborhood Hits	54
SwissProt Accessions	Q9JHS4, Q9WVD1	Gene names	Clpx
Domain Architecture
Description	ATP-dependent Clp protease ATP-binding subunit ClpX-like, mitochondrial precursor.

RUVB1_HUMAN
NC score	0.351195 (rank : 54)	θ value	0.00175202 (rank : 51)
Query Neighborhood Hits	112	Target Neighborhood Hits	78	Shared Neighborhood Hits	65
SwissProt Accessions	Q9Y265, Q9BSX9	Gene names	RUVBL1, NMP238, TIP49, TIP49A
Domain Architecture
Description	RuvB-like 1 (EC 3.6.1.-) (49 kDa TATA box-binding protein-interacting protein) (49 kDa TBP-interacting protein) (TIP49a) (Pontin 52) (Nuclear matrix protein 238) (NMP 238) (54 kDa erythrocyte cytosolic protein) (ECP-54) (TIP60-associated protein 54-alpha) (TAP54-alpha).

RUVB1_MOUSE
NC score	0.351158 (rank : 55)	θ value	0.00175202 (rank : 52)
Query Neighborhood Hits	112	Target Neighborhood Hits	78	Shared Neighborhood Hits	65
SwissProt Accessions	P60122, O35753	Gene names	Ruvbl1, Tip49, Tip49a
Domain Architecture
Description	RuvB-like 1 (EC 3.6.1.-) (49 kDa TATA box-binding protein-interacting protein) (49 kDa TBP-interacting protein) (TIP49a) (Pontin 52) (DNA helicase p50).

WRIP1_MOUSE
NC score	0.267224 (rank : 56)	θ value	0.00509761 (rank : 53)
Query Neighborhood Hits	112	Target Neighborhood Hits	93	Shared Neighborhood Hits	57
SwissProt Accessions	Q91XU0, Q3TCT7, Q6PDF0, Q8BUW5, Q8BWP6, Q8BY55, Q921W3, Q9EQL3	Gene names	Wrnip1, Whip
Domain Architecture	No domain graphic available
Description	ATPase WRNIP1 (Werner helicase-interacting protein 1).

WRIP1_HUMAN
NC score	0.263251 (rank : 57)	θ value	0.00665767 (rank : 54)
Query Neighborhood Hits	112	Target Neighborhood Hits	100	Shared Neighborhood Hits	56
SwissProt Accessions	Q96S55, Q53EP6, Q59ET8, Q5W0E2, Q5W0E4, Q8WV26, Q9H681, Q9NRJ6	Gene names	WRNIP1, WHIP
Domain Architecture	No domain graphic available
Description	ATPase WRNIP1 (Werner helicase-interacting protein 1).

RUVB2_HUMAN
NC score	0.165749 (rank : 58)	θ value	0.0113563 (rank : 57)
Query Neighborhood Hits	112	Target Neighborhood Hits	43	Shared Neighborhood Hits	41
SwissProt Accessions	Q9Y230, Q6PK27, Q9Y361	Gene names	RUVBL2, TIP48, TIP49B
Domain Architecture
Description	RuvB-like 2 (EC 3.6.1.-) (48 kDa TATA box-binding protein-interacting protein) (48 kDa TBP-interacting protein) (TIP49b) (Repressing pontin 52) (Reptin 52) (51 kDa erythrocyte cytosolic protein) (ECP-51) (TIP60-associated protein 54-beta) (TAP54-beta).

RUVB2_MOUSE
NC score	0.163084 (rank : 59)	θ value	0.0113563 (rank : 58)
Query Neighborhood Hits	112	Target Neighborhood Hits	42	Shared Neighborhood Hits	40
SwissProt Accessions	Q9WTM5	Gene names	Ruvbl2
Domain Architecture
Description	RuvB-like 2 (EC 3.6.1.-) (p47 protein).

KAD6_HUMAN
NC score	0.144292 (rank : 60)	θ value	0.0563607 (rank : 60)
Query Neighborhood Hits	112	Target Neighborhood Hits	46	Shared Neighborhood Hits	29
SwissProt Accessions	Q9Y3D8	Gene names	AK6
Domain Architecture
Description	Adenylate kinase isoenzyme 6 (EC 2.7.4.3) (ATP-AMP transphosphorylase 6).

RFC1_MOUSE
NC score	0.141742 (rank : 61)	θ value	0.62314 (rank : 73)
Query Neighborhood Hits	112	Target Neighborhood Hits	290	Shared Neighborhood Hits	58
SwissProt Accessions	P35601	Gene names	Rfc1, Ibf-1, Recc1
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (A1-P145) (Differentiation- specific element-binding protein) (ISRE-binding protein).

RFC4_HUMAN
NC score	0.135026 (rank : 62)	θ value	0.365318 (rank : 67)
Query Neighborhood Hits	112	Target Neighborhood Hits	64	Shared Neighborhood Hits	44
SwissProt Accessions	P35249, Q6FHX7	Gene names	RFC4
Domain Architecture
Description	Replication factor C subunit 4 (Replication factor C 37 kDa subunit) (RF-C 37 kDa subunit) (RFC37) (Activator 1 37 kDa subunit) (A1 37 kDa subunit).

RFC1_HUMAN
NC score	0.126083 (rank : 63)	θ value	1.38821 (rank : 80)
Query Neighborhood Hits	112	Target Neighborhood Hits	352	Shared Neighborhood Hits	52
SwissProt Accessions	P35251, Q5XKF5, Q6PKU0, Q86V41, Q86V46	Gene names	RFC1, RFC140
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (DNA-binding protein PO-GA).

RFC4_MOUSE
NC score	0.123347 (rank : 64)	θ value	0.365318 (rank : 68)
Query Neighborhood Hits	112	Target Neighborhood Hits	65	Shared Neighborhood Hits	44
SwissProt Accessions	Q99J62	Gene names	Rfc4
Domain Architecture	No domain graphic available
Description	Replication factor C subunit 4.

KAD6_MOUSE
NC score	0.122743 (rank : 65)	θ value	0.0961366 (rank : 61)
Query Neighborhood Hits	112	Target Neighborhood Hits	34	Shared Neighborhood Hits	23
SwissProt Accessions	Q8VCP8	Gene names	Ak6
Domain Architecture	No domain graphic available
Description	Adenylate kinase isoenzyme 6 (EC 2.7.4.3) (ATP-AMP transphosphorylase 6).

THNSL_MOUSE
NC score	0.109294 (rank : 66)	θ value	6.88961 (rank : 103)
Query Neighborhood Hits	112	Target Neighborhood Hits	47	Shared Neighborhood Hits	37
SwissProt Accessions	Q8BH55	Gene names	Thnsl1
Domain Architecture	No domain graphic available
Description	Threonine synthase-like 1.

THNSL_HUMAN
NC score	0.105989 (rank : 67)	θ value	6.88961 (rank : 102)
Query Neighborhood Hits	112	Target Neighborhood Hits	47	Shared Neighborhood Hits	38
SwissProt Accessions	Q8IYQ7, Q5VV21	Gene names	THNSL1
Domain Architecture	No domain graphic available
Description	Threonine synthase-like 1.

RFC5_MOUSE
NC score	0.084997 (rank : 68)	θ value	θ > 10 (rank : 114)
Query Neighborhood Hits	112	Target Neighborhood Hits	58	Shared Neighborhood Hits	40
SwissProt Accessions	Q9D0F6	Gene names	Rfc5
Domain Architecture
Description	Replication factor C subunit 5 (Replication factor C 36 kDa subunit) (RF-C 36 kDa subunit) (RFC36) (Activator 1 36 kDa subunit) (A1 36 kDa subunit).

RFC5_HUMAN
NC score	0.084220 (rank : 69)	θ value	θ > 10 (rank : 113)
Query Neighborhood Hits	112	Target Neighborhood Hits	60	Shared Neighborhood Hits	36
SwissProt Accessions	P40937	Gene names	RFC5
Domain Architecture
Description	Replication factor C subunit 5 (Replication factor C 36 kDa subunit) (RF-C 36 kDa subunit) (RFC36) (Activator 1 36 kDa subunit) (A1 36 kDa subunit).

RAD17_MOUSE
NC score	0.076660 (rank : 70)	θ value	1.38821 (rank : 79)
Query Neighborhood Hits	112	Target Neighborhood Hits	63	Shared Neighborhood Hits	29
SwissProt Accessions	Q6NXW6, O88934, O89024	Gene names	Rad17
Domain Architecture	No domain graphic available
Description	Cell cycle checkpoint protein RAD17.

RFC2_HUMAN
NC score	0.075810 (rank : 71)	θ value	0.163984 (rank : 64)
Query Neighborhood Hits	112	Target Neighborhood Hits	46	Shared Neighborhood Hits	27
SwissProt Accessions	P35250, P32846, Q9BU93	Gene names	RFC2
Domain Architecture
Description	Replication factor C subunit 2 (Replication factor C 40 kDa subunit) (RF-C 40 kDa subunit) (RFC40) (Activator 1 40 kDa subunit) (A1 40 kDa subunit).

RFC2_MOUSE
NC score	0.072792 (rank : 72)	θ value	0.279714 (rank : 66)
Query Neighborhood Hits	112	Target Neighborhood Hits	46	Shared Neighborhood Hits	27
SwissProt Accessions	Q9WUK4	Gene names	Rfc2
Domain Architecture
Description	Replication factor C subunit 2 (Replication factor C 40 kDa subunit) (RF-C 40 kDa subunit) (RFC40) (Activator 1 40 kDa subunit) (A1 40 kDa subunit).

MDN1_HUMAN
NC score	0.056829 (rank : 73)	θ value	0.163984 (rank : 63)
Query Neighborhood Hits	112	Target Neighborhood Hits	662	Shared Neighborhood Hits	36
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

RAD17_HUMAN
NC score	0.055546 (rank : 74)	θ value	1.06291 (rank : 77)
Query Neighborhood Hits	112	Target Neighborhood Hits	44	Shared Neighborhood Hits	18
SwissProt Accessions	O75943, O75714, Q7Z3S4, Q9UNK7, Q9UNR7, Q9UNR8, Q9UPF5	Gene names	RAD17, R24L
Domain Architecture	No domain graphic available
Description	Cell cycle checkpoint protein RAD17 (hRad17) (RF-C/activator 1 homolog).

AQR_MOUSE
NC score	0.045391 (rank : 75)	θ value	0.62314 (rank : 71)
Query Neighborhood Hits	112	Target Neighborhood Hits	62	Shared Neighborhood Hits	14
SwissProt Accessions	Q8CFQ3, P97871, Q3U9N1, Q3ULE8, Q80TX8	Gene names	Aqr, Kiaa0560
Domain Architecture	No domain graphic available
Description	Intron-binding protein aquarius.

AQR_HUMAN
NC score	0.044220 (rank : 76)	θ value	0.62314 (rank : 70)
Query Neighborhood Hits	112	Target Neighborhood Hits	88	Shared Neighborhood Hits	14
SwissProt Accessions	O60306, Q2YDX9, Q6IRU8, Q6PIC8	Gene names	AQR, KIAA0560
Domain Architecture	No domain graphic available
Description	Intron-binding protein aquarius (Intron-binding protein of 160 kDa) (IBP160).

OXR1_MOUSE
NC score	0.022301 (rank : 77)	θ value	0.0252991 (rank : 59)
Query Neighborhood Hits	112	Target Neighborhood Hits	516	Shared Neighborhood Hits	9
SwissProt Accessions	Q4KMM3, Q5FWW1, Q99L06, Q99MK1, Q99MP4	Gene names	Oxr1, C7
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1 (Protein C7).

MOV10_HUMAN
NC score	0.019637 (rank : 78)	θ value	5.27518 (rank : 94)
Query Neighborhood Hits	112	Target Neighborhood Hits	46	Shared Neighborhood Hits	16
SwissProt Accessions	Q9HCE1, Q8TEF0, Q9BSY3, Q9BUJ9	Gene names	MOV10, KIAA1631
Domain Architecture
Description	Putative helicase MOV-10 (EC 3.6.1.-) (Moloney leukemia virus 10 protein).

EXOC4_MOUSE
NC score	0.017579 (rank : 79)	θ value	1.81305 (rank : 81)
Query Neighborhood Hits	112	Target Neighborhood Hits	86	Shared Neighborhood Hits	4
SwissProt Accessions	O35382	Gene names	Exoc4, Sec8, Sec8l1
Domain Architecture
Description	Exocyst complex component 4 (Exocyst complex component Sec8).

IWS1_MOUSE
NC score	0.017442 (rank : 80)	θ value	0.47712 (rank : 69)
Query Neighborhood Hits	112	Target Neighborhood Hits	1258	Shared Neighborhood Hits	15
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

NALP7_HUMAN
NC score	0.016579 (rank : 81)	θ value	8.99809 (rank : 110)
Query Neighborhood Hits	112	Target Neighborhood Hits	65	Shared Neighborhood Hits	14
SwissProt Accessions	Q8WX94, Q7RTR1	Gene names	NALP7, NOD12, PYPAF3
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 7 (PYRIN-containing APAF1-like protein 3).

MRP3_HUMAN
NC score	0.015536 (rank : 82)	θ value	0.279714 (rank : 65)
Query Neighborhood Hits	112	Target Neighborhood Hits	125	Shared Neighborhood Hits	12
SwissProt Accessions	O15438, O60265, O60922, O75621, O95078, O95289, O95290, Q9UN52	Gene names	ABCC3, CMOAT2, MLP2, MRP3
Domain Architecture
Description	Canalicular multispecific organic anion transporter 2 (ATP-binding cassette sub-family C member 3) (Multidrug resistance-associated protein 3) (Multi-specific organic anion transporter-D) (MOAT-D).

MOV10_MOUSE
NC score	0.015520 (rank : 83)	θ value	5.27518 (rank : 95)
Query Neighborhood Hits	112	Target Neighborhood Hits	39	Shared Neighborhood Hits	15
SwissProt Accessions	P23249, Q9DC64	Gene names	Mov10, Gb110
Domain Architecture
Description	Putative helicase MOV-10 (EC 3.6.1.-) (Moloney leukemia virus 10 protein).

MRP6_HUMAN
NC score	0.012684 (rank : 84)	θ value	4.03905 (rank : 90)
Query Neighborhood Hits	112	Target Neighborhood Hits	113	Shared Neighborhood Hits	9
SwissProt Accessions	O95255, P78420, Q9UMZ7	Gene names	ABCC6, ARA, MRP6
Domain Architecture
Description	Multidrug resistance-associated protein 6 (ATP-binding cassette sub- family C member 6) (Anthracycline resistance-associated protein) (Multi-specific organic anion transporter-E) (MOAT-E).

IWS1_HUMAN
NC score	0.011580 (rank : 85)	θ value	0.813845 (rank : 75)
Query Neighborhood Hits	112	Target Neighborhood Hits	1241	Shared Neighborhood Hits	13
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

FOXO1_MOUSE
NC score	0.011344 (rank : 86)	θ value	0.62314 (rank : 72)
Query Neighborhood Hits	112	Target Neighborhood Hits	118	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R1E0	Gene names	Foxo1a, Fkhr, Foxo1
Domain Architecture
Description	Forkhead box protein O1A (Forkhead in rhabdomyosarcoma).

CLPB_HUMAN
NC score	0.011099 (rank : 87)	θ value	8.99809 (rank : 106)
Query Neighborhood Hits	112	Target Neighborhood Hits	265	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H078, Q8ND11, Q9H8Y0	Gene names	CLPB, SKD3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

SACS_MOUSE
NC score	0.011015 (rank : 88)	θ value	4.03905 (rank : 93)
Query Neighborhood Hits	112	Target Neighborhood Hits	99	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JLC8	Gene names	Sacs
Domain Architecture
Description	Sacsin.

PHAR3_HUMAN
NC score	0.010584 (rank : 89)	θ value	3.0926 (rank : 88)
Query Neighborhood Hits	112	Target Neighborhood Hits	169	Shared Neighborhood Hits	4
SwissProt Accessions	Q96KR7, Q707P6, Q9H4T4	Gene names	PHACTR3, C20orf101, SCAPIN1
Domain Architecture	No domain graphic available
Description	Phosphatase and actin regulator 3 (Scapinin) (Scaffold-associated PP1- inhibiting protein).

MRP6_MOUSE
NC score	0.010577 (rank : 90)	θ value	0.813845 (rank : 76)
Query Neighborhood Hits	112	Target Neighborhood Hits	105	Shared Neighborhood Hits	5
SwissProt Accessions	Q9R1S7, Q80YB6	Gene names	Abcc6, Mrp6
Domain Architecture	No domain graphic available
Description	Multidrug resistance-associated protein 6 (ATP-binding cassette sub- family C member 6).

NALP5_MOUSE
NC score	0.010471 (rank : 91)	θ value	6.88961 (rank : 98)
Query Neighborhood Hits	112	Target Neighborhood Hits	560	Shared Neighborhood Hits	17
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

PACE1_HUMAN
NC score	0.010215 (rank : 92)	θ value	2.36792 (rank : 85)
Query Neighborhood Hits	112	Target Neighborhood Hits	74	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IZE3, Q5THA6, Q5THA8, Q8IZN9, Q96C56, Q9UBK6	Gene names	SCYL3, PACE1
Domain Architecture	No domain graphic available
Description	Protein-associating with the carboxyl-terminal domain of ezrin (Ezrin- binding protein PACE-1) (SCY1-like protein 3).

FOXO1_HUMAN
NC score	0.010163 (rank : 93)	θ value	1.38821 (rank : 78)
Query Neighborhood Hits	112	Target Neighborhood Hits	126	Shared Neighborhood Hits	3
SwissProt Accessions	Q12778, O43523, Q5VYC7, Q6NSK6	Gene names	FOXO1A, FKHR
Domain Architecture
Description	Forkhead box protein O1A (Forkhead in rhabdomyosarcoma).

ATRX_MOUSE
NC score	0.010107 (rank : 94)	θ value	0.813845 (rank : 74)
Query Neighborhood Hits	112	Target Neighborhood Hits	682	Shared Neighborhood Hits	11
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

DYHC_MOUSE
NC score	0.008737 (rank : 95)	θ value	6.88961 (rank : 97)
Query Neighborhood Hits	112	Target Neighborhood Hits	729	Shared Neighborhood Hits	17
SwissProt Accessions	Q9JHU4	Gene names	Dync1h1, Dnch1, Dnchc1
Domain Architecture
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

DYHC_HUMAN
NC score	0.008730 (rank : 96)	θ value	6.88961 (rank : 96)
Query Neighborhood Hits	112	Target Neighborhood Hits	733	Shared Neighborhood Hits	17
SwissProt Accessions	Q14204, Q6DKQ7, Q8WU28, Q92814, Q9Y4G5	Gene names	DYNC1H1, DNCH1, DNECL, KIAA0325
Domain Architecture	No domain graphic available
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

CLPB_MOUSE
NC score	0.008559 (rank : 97)	θ value	8.99809 (rank : 107)
Query Neighborhood Hits	112	Target Neighborhood Hits	289	Shared Neighborhood Hits	7
SwissProt Accessions	Q60649	Gene names	Clpb, Skd3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

S29A3_HUMAN
NC score	0.008520 (rank : 98)	θ value	6.88961 (rank : 101)
Query Neighborhood Hits	112	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BZD2, Q7RTT8, Q8IVZ0	Gene names	SLC29A3, ENT3
Domain Architecture
Description	Equilibrative nucleoside transporter 3 (Solute carrier family 29 member 3).

PHAR3_MOUSE
NC score	0.008249 (rank : 99)	θ value	6.88961 (rank : 99)
Query Neighborhood Hits	112	Target Neighborhood Hits	206	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BYK5, Q8BYS8, Q8C058, Q9DB87	Gene names	Phactr3, Scapin1
Domain Architecture	No domain graphic available
Description	Phosphatase and actin regulator 3 (Scapinin) (Scaffold-associated PP1- inhibiting protein).

PI51C_HUMAN
NC score	0.008034 (rank : 100)	θ value	4.03905 (rank : 92)
Query Neighborhood Hits	112	Target Neighborhood Hits	109	Shared Neighborhood Hits	6
SwissProt Accessions	O60331, Q7LE07	Gene names	PIP5K1C, KIAA0589
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type I gamma) (PtdIns(4)P- 5-kinase gamma) (PtdInsPKIgamma) (PIP5KIgamma).

NEBU_HUMAN
NC score	0.007039 (rank : 101)	θ value	1.81305 (rank : 82)
Query Neighborhood Hits	112	Target Neighborhood Hits	420	Shared Neighborhood Hits	4
SwissProt Accessions	P20929, Q15346	Gene names	NEB
Domain Architecture
Description	Nebulin.

PI51C_MOUSE
NC score	0.006453 (rank : 102)	θ value	6.88961 (rank : 100)
Query Neighborhood Hits	112	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	O70161, Q505A1, Q80TW9, Q8VCU5	Gene names	Pip5k1c, Kiaa0589
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type I gamma) (PtdIns(4)P- 5-kinase gamma) (PtdInsPKIgamma) (PIP5KIgamma).

NOS1_HUMAN
NC score	0.006117 (rank : 103)	θ value	2.36792 (rank : 84)
Query Neighborhood Hits	112	Target Neighborhood Hits	218	Shared Neighborhood Hits	3
SwissProt Accessions	P29475	Gene names	NOS1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

PHF8_HUMAN
NC score	0.005920 (rank : 104)	θ value	2.36792 (rank : 86)
Query Neighborhood Hits	112	Target Neighborhood Hits	105	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UPP1, Q5H9U5, Q5VUJ4, Q7Z6D4, Q9HAH2	Gene names	PHF8, KIAA1111, ZNF422
Domain Architecture	No domain graphic available
Description	PHD finger protein 8.

NOS1_MOUSE
NC score	0.004907 (rank : 105)	θ value	8.99809 (rank : 111)
Query Neighborhood Hits	112	Target Neighborhood Hits	155	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z0J4, Q64208	Gene names	Nos1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

CE290_HUMAN
NC score	0.004745 (rank : 106)	θ value	4.03905 (rank : 89)
Query Neighborhood Hits	112	Target Neighborhood Hits	1553	Shared Neighborhood Hits	16
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

NAL12_HUMAN
NC score	0.004252 (rank : 107)	θ value	8.99809 (rank : 109)
Query Neighborhood Hits	112	Target Neighborhood Hits	96	Shared Neighborhood Hits	5
SwissProt Accessions	P59046, Q8NEU4, Q9BY26	Gene names	NALP12, PYPAF7, RNO
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 12 (PYRIN-containing APAF1-like protein 7) (Monarch-1) (Regulated by nitric oxide).

AT2A2_HUMAN
NC score	0.001550 (rank : 108)	θ value	8.99809 (rank : 104)
Query Neighborhood Hits	112	Target Neighborhood Hits	66	Shared Neighborhood Hits	3
SwissProt Accessions	P16615, P16614	Gene names	ATP2A2, ATP2B
Domain Architecture
Description	Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (EC 3.6.3.8) (Calcium pump 2) (SERCA2) (SR Ca(2+)-ATPase 2) (Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform) (Endoplasmic reticulum class 1/2 Ca(2+) ATPase).

AT2A2_MOUSE
NC score	0.001542 (rank : 109)	θ value	8.99809 (rank : 105)
Query Neighborhood Hits	112	Target Neighborhood Hits	68	Shared Neighborhood Hits	3
SwissProt Accessions	O55143, Q9R2A9, Q9WUT5	Gene names	Atp2a2
Domain Architecture
Description	Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (EC 3.6.3.8) (Calcium pump 2) (SERCA2) (SR Ca(2+)-ATPase 2) (Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform) (Endoplasmic reticulum class 1/2 Ca(2+) ATPase).

MYO9B_HUMAN
NC score	0.000375 (rank : 110)	θ value	2.36792 (rank : 83)
Query Neighborhood Hits	112	Target Neighborhood Hits	641	Shared Neighborhood Hits	6
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

ANR18_HUMAN
NC score	-0.000545 (rank : 111)	θ value	3.0926 (rank : 87)
Query Neighborhood Hits	112	Target Neighborhood Hits	1106	Shared Neighborhood Hits	13
SwissProt Accessions	Q8IVF6, Q7Z468	Gene names	ANKRD18A, KIAA2015
Domain Architecture
Description	Ankyrin repeat domain-containing protein 18A.

PCDG2_HUMAN
NC score	-0.001143 (rank : 112)	θ value	4.03905 (rank : 91)
Query Neighborhood Hits	112	Target Neighborhood Hits	151	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y5H1, Q9Y5D5	Gene names	PCDHGA2
Domain Architecture
Description	Protocadherin gamma A2 precursor (PCDH-gamma-A2).

KIF4A_MOUSE
NC score	-0.002372 (rank : 113)	θ value	8.99809 (rank : 108)
Query Neighborhood Hits	112	Target Neighborhood Hits	1033	Shared Neighborhood Hits	8
SwissProt Accessions	P33174	Gene names	Kif4a, Kif4, Kns4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

ZN710_HUMAN
NC score	-0.005984 (rank : 114)	θ value	8.99809 (rank : 112)
Query Neighborhood Hits	112	Target Neighborhood Hits	796	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N1W2, Q6ZMK9, Q8NDU0	Gene names	ZNF710
Domain Architecture	No domain graphic available
Description	Zinc finger protein 710.