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Network neighborhood for query Sequence : KTNA1_HUMAN

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KTNA1_HUMAN
SwissProt Accessions	O75449, Q5TFA8, Q5TFA9, Q86VN2, Q9NU52	Gene names	KATNA1
Domain Architecture	No domain graphic available
Description	Katanin p60 ATPase-containing subunit A1 (EC 3.6.4.3) (Katanin p60 subunit A1) (p60 katanin).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

KTNA1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	117	Target Neighborhood Hits	117	Shared Neighborhood Hits	117
SwissProt Accessions	O75449, Q5TFA8, Q5TFA9, Q86VN2, Q9NU52	Gene names	KATNA1
Domain Architecture	No domain graphic available
Description	Katanin p60 ATPase-containing subunit A1 (EC 3.6.4.3) (Katanin p60 subunit A1) (p60 katanin).

KTNA1_MOUSE
θ value	0 (rank : 2)	NC score	0.997142 (rank : 2)
Query Neighborhood Hits	117	Target Neighborhood Hits	123	Shared Neighborhood Hits	87
SwissProt Accessions	Q9WV86	Gene names	Katna1
Domain Architecture	No domain graphic available
Description	Katanin p60 ATPase-containing subunit A1 (EC 3.6.4.3) (Katanin p60 subunit A1) (p60 katanin) (Lipotransin).

KATL1_HUMAN
θ value	2.40406e-178 (rank : 3)	NC score	0.995133 (rank : 4)
Query Neighborhood Hits	117	Target Neighborhood Hits	80	Shared Neighborhood Hits	67
SwissProt Accessions	Q9BW62	Gene names	KATNAL1
Domain Architecture	No domain graphic available
Description	Katanin p60 ATPase-containing subunit A-like 1 (EC 3.6.4.3) (Katanin p60 subunit A-like 1) (p60 katanin-like 1).

KATL1_MOUSE
θ value	2.25013e-176 (rank : 4)	NC score	0.995159 (rank : 3)
Query Neighborhood Hits	117	Target Neighborhood Hits	77	Shared Neighborhood Hits	67
SwissProt Accessions	Q8K0T4	Gene names	Katnal1
Domain Architecture	No domain graphic available
Description	Katanin p60 ATPase-containing subunit A-like 1 (EC 3.6.4.3) (Katanin p60 subunit A-like 1) (p60 katanin-like 1).

VPS4A_HUMAN
θ value	5.17823e-64 (rank : 5)	NC score	0.957970 (rank : 11)
Query Neighborhood Hits	117	Target Neighborhood Hits	95	Shared Neighborhood Hits	63
SwissProt Accessions	Q9UN37, Q8TF07, Q9UI03, Q9Y582	Gene names	VPS4A, VPS4
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associating protein 4A (SKD2 protein) (hVPS4) (VPS4-1).

VPS4A_MOUSE
θ value	5.17823e-64 (rank : 6)	NC score	0.957939 (rank : 12)
Query Neighborhood Hits	117	Target Neighborhood Hits	94	Shared Neighborhood Hits	63
SwissProt Accessions	Q8VEJ9, Q3TXT2	Gene names	Vps4a
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associating protein 4A.

SPAST_HUMAN
θ value	6.76295e-64 (rank : 7)	NC score	0.962764 (rank : 5)
Query Neighborhood Hits	117	Target Neighborhood Hits	100	Shared Neighborhood Hits	61
SwissProt Accessions	Q9UBP0, Q9UPR9	Gene names	SPAST, KIAA1083, SPG4
Domain Architecture
Description	Spastin.

SPAST_MOUSE
θ value	7.47731e-63 (rank : 8)	NC score	0.961469 (rank : 6)
Query Neighborhood Hits	117	Target Neighborhood Hits	138	Shared Neighborhood Hits	65
SwissProt Accessions	Q9QYY8, Q6ZPY6, Q80VE0, Q9CVK0	Gene names	Spast, Kiaa1083, Spg4
Domain Architecture	No domain graphic available
Description	Spastin.

VPS4B_MOUSE
θ value	7.47731e-63 (rank : 9)	NC score	0.959559 (rank : 10)
Query Neighborhood Hits	117	Target Neighborhood Hits	86	Shared Neighborhood Hits	62
SwissProt Accessions	P46467, Q91W22, Q9R1C9	Gene names	Vps4b, Skd1
Domain Architecture
Description	Vacuolar protein sorting-associating protein 4B (Protein SKD1).

VPS4B_HUMAN
θ value	1.07972e-61 (rank : 10)	NC score	0.959997 (rank : 9)
Query Neighborhood Hits	117	Target Neighborhood Hits	87	Shared Neighborhood Hits	63
SwissProt Accessions	O75351, Q9GZS7	Gene names	VPS4B, SKD1, VPS42
Domain Architecture
Description	Vacuolar protein sorting-associating protein 4B (Protein SKD1).

ATAD1_HUMAN
θ value	5.20228e-48 (rank : 11)	NC score	0.961443 (rank : 7)
Query Neighborhood Hits	117	Target Neighborhood Hits	75	Shared Neighborhood Hits	62
SwissProt Accessions	Q8NBU5, Q6P4B9, Q8N3G1, Q8WYR9, Q969Y3	Gene names	ATAD1
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 1.

ATAD1_MOUSE
θ value	5.20228e-48 (rank : 12)	NC score	0.961443 (rank : 8)
Query Neighborhood Hits	117	Target Neighborhood Hits	75	Shared Neighborhood Hits	62
SwissProt Accessions	Q9D5T0, Q3U8V2, Q9D7A4	Gene names	Atad1
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 1.

FIGN_MOUSE
θ value	1.15895e-47 (rank : 13)	NC score	0.928323 (rank : 17)
Query Neighborhood Hits	117	Target Neighborhood Hits	165	Shared Neighborhood Hits	59
SwissProt Accessions	Q9ERZ6, Q3TPB0, Q3UP57, Q6PCM0	Gene names	Fign
Domain Architecture	No domain graphic available
Description	Fidgetin.

FIGN_HUMAN
θ value	4.40402e-47 (rank : 14)	NC score	0.923864 (rank : 22)
Query Neighborhood Hits	117	Target Neighborhood Hits	176	Shared Neighborhood Hits	57
SwissProt Accessions	Q5HY92, Q9H6M5, Q9NVZ9	Gene names	FIGN
Domain Architecture	No domain graphic available
Description	Fidgetin.

TERA_HUMAN
θ value	7.03111e-45 (rank : 15)	NC score	0.929933 (rank : 13)
Query Neighborhood Hits	117	Target Neighborhood Hits	76	Shared Neighborhood Hits	65
SwissProt Accessions	P55072, Q969G7	Gene names	VCP
Domain Architecture
Description	Transitional endoplasmic reticulum ATPase (TER ATPase) (15S Mg(2+)- ATPase p97 subunit) (Valosin-containing protein) (VCP).

TERA_MOUSE
θ value	9.18288e-45 (rank : 16)	NC score	0.929890 (rank : 14)
Query Neighborhood Hits	117	Target Neighborhood Hits	76	Shared Neighborhood Hits	65
SwissProt Accessions	Q01853	Gene names	Vcp
Domain Architecture
Description	Transitional endoplasmic reticulum ATPase (TER ATPase) (15S Mg(2+)- ATPase p97 subunit) (Valosin-containing protein) (VCP).

PRS8_HUMAN
θ value	1.2411e-41 (rank : 17)	NC score	0.927278 (rank : 18)
Query Neighborhood Hits	117	Target Neighborhood Hits	117	Shared Neighborhood Hits	63
SwissProt Accessions	P62195, O35051, O43208, P47210, P52915, P52916	Gene names	PSMC5, SUG1
Domain Architecture
Description	26S protease regulatory subunit 8 (Proteasome 26S subunit ATPase 5) (Proteasome subunit p45) (p45/SUG) (Thyroid hormone receptor- interacting protein 1) (TRIP1).

PRS8_MOUSE
θ value	1.2411e-41 (rank : 18)	NC score	0.927278 (rank : 19)
Query Neighborhood Hits	117	Target Neighborhood Hits	117	Shared Neighborhood Hits	63
SwissProt Accessions	P62196, O35051, P47210, P52915, P52916, Q3UL51, Q9CWN5	Gene names	Psmc5, Sug1
Domain Architecture
Description	26S protease regulatory subunit 8 (Proteasome 26S subunit ATPase 5) (Proteasome subunit p45) (p45/SUG) (mSUG1).

PRS10_HUMAN
θ value	5.21438e-40 (rank : 19)	NC score	0.928710 (rank : 15)
Query Neighborhood Hits	117	Target Neighborhood Hits	95	Shared Neighborhood Hits	65
SwissProt Accessions	P62333, P49719, Q6IBU3, Q92524	Gene names	PSMC6, SUG2
Domain Architecture
Description	26S protease regulatory subunit S10B (Proteasome subunit p42) (Proteasome 26S subunit ATPase 6).

PRS10_MOUSE
θ value	5.21438e-40 (rank : 20)	NC score	0.928710 (rank : 16)
Query Neighborhood Hits	117	Target Neighborhood Hits	95	Shared Neighborhood Hits	65
SwissProt Accessions	P62334, P49719, Q3TKK1, Q810A6, Q92524, Q9CXH9	Gene names	Psmc6, Sug2
Domain Architecture
Description	26S protease regulatory subunit S10B (Proteasome subunit p42) (Proteasome 26S subunit ATPase 6).

PRS4_HUMAN
θ value	1.51715e-39 (rank : 21)	NC score	0.923488 (rank : 23)
Query Neighborhood Hits	117	Target Neighborhood Hits	84	Shared Neighborhood Hits	64
SwissProt Accessions	P62191, P49014, Q03527, Q6IAW0, Q96AZ3	Gene names	PSMC1
Domain Architecture
Description	26S protease regulatory subunit 4 (P26s4) (Proteasome 26S subunit ATPase 1).

PRS4_MOUSE
θ value	1.51715e-39 (rank : 22)	NC score	0.923488 (rank : 24)
Query Neighborhood Hits	117	Target Neighborhood Hits	84	Shared Neighborhood Hits	64
SwissProt Accessions	P62192, P49014, Q03527, Q96AZ3	Gene names	Psmc1
Domain Architecture
Description	26S protease regulatory subunit 4 (P26s4) (Proteasome 26S subunit ATPase 1).

NVL_HUMAN
θ value	5.76516e-39 (rank : 23)	NC score	0.919351 (rank : 27)
Query Neighborhood Hits	117	Target Neighborhood Hits	112	Shared Neighborhood Hits	66
SwissProt Accessions	O15381, Q96EM7	Gene names	NVL
Domain Architecture
Description	Nuclear valosin-containing protein-like (Nuclear VCP-like protein) (NVLp).

NVL_MOUSE
θ value	7.52953e-39 (rank : 24)	NC score	0.919901 (rank : 26)
Query Neighborhood Hits	117	Target Neighborhood Hits	110	Shared Neighborhood Hits	65
SwissProt Accessions	Q9DBY8, Q3USC4, Q8BW27, Q8K2B5	Gene names	Nvl
Domain Architecture
Description	Nuclear valosin-containing protein-like (Nuclear VCP-like protein) (NVLp).

PRS6A_HUMAN
θ value	1.08726e-37 (rank : 25)	NC score	0.924449 (rank : 21)
Query Neighborhood Hits	117	Target Neighborhood Hits	87	Shared Neighborhood Hits	60
SwissProt Accessions	P17980, Q96HD3	Gene names	PSMC3, TBP1
Domain Architecture
Description	26S protease regulatory subunit 6A (Proteasome 26S subunit ATPase 3) (TAT-binding protein 1) (TBP-1) (Proteasome subunit P50).

PRS6A_MOUSE
θ value	2.42216e-37 (rank : 26)	NC score	0.924634 (rank : 20)
Query Neighborhood Hits	117	Target Neighborhood Hits	85	Shared Neighborhood Hits	60
SwissProt Accessions	O88685	Gene names	Psmc3, Tbp1
Domain Architecture
Description	26S protease regulatory subunit 6A (Proteasome 26S subunit ATPase 3) (TAT-binding protein 1) (TBP-1).

PEX6_MOUSE
θ value	7.04741e-37 (rank : 27)	NC score	0.914815 (rank : 33)
Query Neighborhood Hits	117	Target Neighborhood Hits	94	Shared Neighborhood Hits	63
SwissProt Accessions	Q99LC9, Q6YNQ9	Gene names	Pex6
Domain Architecture	No domain graphic available
Description	Peroxisome assembly factor 2 (PAF-2) (Peroxisomal-type ATPase 1) (Peroxin-6) (Peroxisomal biogenesis factor 6).

PEX6_HUMAN
θ value	2.67802e-36 (rank : 28)	NC score	0.915081 (rank : 32)
Query Neighborhood Hits	117	Target Neighborhood Hits	99	Shared Neighborhood Hits	65
SwissProt Accessions	Q13608, Q8WYQ2, Q99476	Gene names	PEX6, PXAAA1
Domain Architecture
Description	Peroxisome assembly factor 2 (PAF-2) (Peroxisomal-type ATPase 1) (Peroxin-6) (Peroxisomal biogenesis factor 6).

PEX1_HUMAN
θ value	2.96089e-35 (rank : 29)	NC score	0.922484 (rank : 25)
Query Neighborhood Hits	117	Target Neighborhood Hits	98	Shared Neighborhood Hits	62
SwissProt Accessions	O43933, Q96S71, Q96S72, Q96S73, Q99994	Gene names	PEX1
Domain Architecture
Description	Peroxisome biogenesis factor 1 (Peroxin-1) (Peroxisome biogenesis disorder protein 1).

YMEL1_MOUSE
θ value	1.12514e-34 (rank : 30)	NC score	0.903856 (rank : 34)
Query Neighborhood Hits	117	Target Neighborhood Hits	76	Shared Neighborhood Hits	60
SwissProt Accessions	O88967, Q7TNN5	Gene names	Yme1l1
Domain Architecture
Description	ATP-dependent metalloprotease YME1L1 (EC 3.4.24.-) (YME1-like protein 1) (ATP-dependent metalloprotease FtsH1).

ATAD2_HUMAN
θ value	4.72714e-33 (rank : 31)	NC score	0.853903 (rank : 43)
Query Neighborhood Hits	117	Target Neighborhood Hits	322	Shared Neighborhood Hits	64
SwissProt Accessions	Q6PL18, Q658P2, Q68CQ0, Q6PJV6, Q8N890, Q9UHS5	Gene names	ATAD2
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 2.

ATAD2_MOUSE
θ value	8.06329e-33 (rank : 32)	NC score	0.871140 (rank : 42)
Query Neighborhood Hits	117	Target Neighborhood Hits	167	Shared Neighborhood Hits	61
SwissProt Accessions	Q8CDM1	Gene names	Atad2
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 2.

AFG31_MOUSE
θ value	1.37539e-32 (rank : 33)	NC score	0.898991 (rank : 36)
Query Neighborhood Hits	117	Target Neighborhood Hits	74	Shared Neighborhood Hits	62
SwissProt Accessions	Q920A7	Gene names	Afg3l1
Domain Architecture
Description	AFG3-like protein 1 (EC 3.4.24.-).

PRS6B_HUMAN
θ value	1.37539e-32 (rank : 34)	NC score	0.918038 (rank : 30)
Query Neighborhood Hits	117	Target Neighborhood Hits	85	Shared Neighborhood Hits	57
SwissProt Accessions	P43686, Q96FV5, Q9UBM3, Q9UEX3	Gene names	PSMC4, TBP7
Domain Architecture
Description	26S protease regulatory subunit 6B (Proteasome 26S subunit ATPase 4) (MIP224) (MB67-interacting protein) (TAT-binding protein 7) (TBP-7).

PRS7_HUMAN
θ value	1.79631e-32 (rank : 35)	NC score	0.918791 (rank : 28)
Query Neighborhood Hits	117	Target Neighborhood Hits	66	Shared Neighborhood Hits	61
SwissProt Accessions	P35998	Gene names	PSMC2, MSS1
Domain Architecture
Description	26S protease regulatory subunit 7 (Proteasome 26S subunit ATPase 2) (Protein MSS1).

PRS7_MOUSE
θ value	1.79631e-32 (rank : 36)	NC score	0.918782 (rank : 29)
Query Neighborhood Hits	117	Target Neighborhood Hits	67	Shared Neighborhood Hits	61
SwissProt Accessions	P46471, O08531, Q3TGX5, Q9DBA1	Gene names	Psmc2, Mss1
Domain Architecture
Description	26S protease regulatory subunit 7 (Proteasome 26S subunit ATPase 2) (Protein MSS1).

PRS6B_MOUSE
θ value	6.82597e-32 (rank : 37)	NC score	0.916862 (rank : 31)
Query Neighborhood Hits	117	Target Neighborhood Hits	89	Shared Neighborhood Hits	57
SwissProt Accessions	P54775	Gene names	Psmc4, Tbp7
Domain Architecture
Description	26S protease regulatory subunit 6B (Proteasome 26S subunit ATPase 4) (MIP224) (MB67-interacting protein) (TAT-binding protein 7) (TBP-7) (CIP21).

AFG32_HUMAN
θ value	3.3877e-31 (rank : 38)	NC score	0.893148 (rank : 38)
Query Neighborhood Hits	117	Target Neighborhood Hits	72	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Y4W6	Gene names	AFG3L2
Domain Architecture
Description	AFG3-like protein 2 (EC 3.4.24.-) (Paraplegin-like protein).

AFG32_MOUSE
θ value	4.42448e-31 (rank : 39)	NC score	0.892973 (rank : 39)
Query Neighborhood Hits	117	Target Neighborhood Hits	73	Shared Neighborhood Hits	62
SwissProt Accessions	Q8JZQ2	Gene names	Afg3l2
Domain Architecture	No domain graphic available
Description	AFG3-like protein 2 (EC 3.4.24.-).

YMEL1_HUMAN
θ value	7.54701e-31 (rank : 40)	NC score	0.900325 (rank : 35)
Query Neighborhood Hits	117	Target Neighborhood Hits	73	Shared Neighborhood Hits	60
SwissProt Accessions	Q96TA2, Q9H1Q0, Q9UMR9	Gene names	YME1L1, FTSH1, YME1L
Domain Architecture
Description	ATP-dependent metalloprotease YME1L1 (EC 3.4.24.-) (YME1-like protein 1) (ATP-dependent metalloprotease FtsH1) (Meg-4) (Presenilin- associated metalloprotease) (PAMP).

SPG7_HUMAN
θ value	3.74554e-30 (rank : 41)	NC score	0.898262 (rank : 37)
Query Neighborhood Hits	117	Target Neighborhood Hits	71	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UQ90, O75756, Q96IB0	Gene names	SPG7, CAR, CMAR, PGN
Domain Architecture
Description	Paraplegin (EC 3.4.24.-) (Spastic paraplegia protein 7).

NSF_HUMAN
θ value	5.79196e-23 (rank : 42)	NC score	0.879257 (rank : 40)
Query Neighborhood Hits	117	Target Neighborhood Hits	74	Shared Neighborhood Hits	64
SwissProt Accessions	P46459, Q9UKZ2	Gene names	NSF
Domain Architecture
Description	Vesicle-fusing ATPase (EC 3.6.4.6) (Vesicular-fusion protein NSF) (N- ethylmaleimide sensitive fusion protein) (NEM-sensitive fusion protein).

NSF_MOUSE
θ value	5.79196e-23 (rank : 43)	NC score	0.878785 (rank : 41)
Query Neighborhood Hits	117	Target Neighborhood Hits	73	Shared Neighborhood Hits	61
SwissProt Accessions	P46460	Gene names	Nsf, Skd2
Domain Architecture
Description	Vesicle-fusing ATPase (EC 3.6.4.6) (Vesicular-fusion protein NSF) (N- ethylmaleimide sensitive fusion protein) (NEM-sensitive fusion protein) (SKD2 protein).

TRP13_HUMAN
θ value	2.13673e-09 (rank : 44)	NC score	0.717015 (rank : 45)
Query Neighborhood Hits	117	Target Neighborhood Hits	81	Shared Neighborhood Hits	58
SwissProt Accessions	Q15645, O15324	Gene names	TRIP13
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 13 (Thyroid hormone receptor interactor 13) (Trip-13) (Human papillomavirus type 16 E1 protein- binding protein) (HPV16 E1 protein-binding protein) (16E1-BP).

TRP13_MOUSE
θ value	2.13673e-09 (rank : 45)	NC score	0.718482 (rank : 44)
Query Neighborhood Hits	117	Target Neighborhood Hits	81	Shared Neighborhood Hits	57
SwissProt Accessions	Q3UA06, Q3UQG6, Q9CWW8	Gene names	Trip13
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 13 (Thyroid hormone receptor interactor 13) (Trip-13).

ATD3B_HUMAN
θ value	4.76016e-09 (rank : 46)	NC score	0.623496 (rank : 47)
Query Neighborhood Hits	117	Target Neighborhood Hits	340	Shared Neighborhood Hits	59
SwissProt Accessions	Q5T9A4, Q6ZRB5, Q9BUK4, Q9ULE7	Gene names	ATAD3B, KIAA1273
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 3B.

ATD3A_HUMAN
θ value	1.38499e-08 (rank : 47)	NC score	0.638767 (rank : 46)
Query Neighborhood Hits	117	Target Neighborhood Hits	248	Shared Neighborhood Hits	63
SwissProt Accessions	Q9NVI7, Q8N275, Q96A50	Gene names	ATAD3A
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 3A.

ATAD3_MOUSE
θ value	2.36244e-08 (rank : 48)	NC score	0.614536 (rank : 48)
Query Neighborhood Hits	117	Target Neighborhood Hits	326	Shared Neighborhood Hits	62
SwissProt Accessions	Q925I1, Q3UE74, Q69ZM7, Q8C6C6	Gene names	Atad3, Atad3a, Kiaa1273
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 3 (AAA-ATPase TOB3).

CLPX_MOUSE
θ value	0.00175202 (rank : 49)	NC score	0.425856 (rank : 52)
Query Neighborhood Hits	117	Target Neighborhood Hits	73	Shared Neighborhood Hits	51
SwissProt Accessions	Q9JHS4, Q9WVD1	Gene names	Clpx
Domain Architecture
Description	ATP-dependent Clp protease ATP-binding subunit ClpX-like, mitochondrial precursor.

CLPX_HUMAN
θ value	0.00228821 (rank : 50)	NC score	0.428688 (rank : 51)
Query Neighborhood Hits	117	Target Neighborhood Hits	72	Shared Neighborhood Hits	51
SwissProt Accessions	O76031, Q9H4D9	Gene names	CLPX
Domain Architecture
Description	ATP-dependent Clp protease ATP-binding subunit ClpX-like, mitochondrial precursor.

RUVB1_HUMAN
θ value	0.0563607 (rank : 51)	NC score	0.324907 (rank : 54)
Query Neighborhood Hits	117	Target Neighborhood Hits	78	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Y265, Q9BSX9	Gene names	RUVBL1, NMP238, TIP49, TIP49A
Domain Architecture
Description	RuvB-like 1 (EC 3.6.1.-) (49 kDa TATA box-binding protein-interacting protein) (49 kDa TBP-interacting protein) (TIP49a) (Pontin 52) (Nuclear matrix protein 238) (NMP 238) (54 kDa erythrocyte cytosolic protein) (ECP-54) (TIP60-associated protein 54-alpha) (TAP54-alpha).

RUVB1_MOUSE
θ value	0.0563607 (rank : 52)	NC score	0.324867 (rank : 55)
Query Neighborhood Hits	117	Target Neighborhood Hits	78	Shared Neighborhood Hits	60
SwissProt Accessions	P60122, O35753	Gene names	Ruvbl1, Tip49, Tip49a
Domain Architecture
Description	RuvB-like 1 (EC 3.6.1.-) (49 kDa TATA box-binding protein-interacting protein) (49 kDa TBP-interacting protein) (TIP49a) (Pontin 52) (DNA helicase p50).

CAC1B_MOUSE
θ value	0.125558 (rank : 53)	NC score	0.010860 (rank : 92)
Query Neighborhood Hits	117	Target Neighborhood Hits	351	Shared Neighborhood Hits	7
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CHD3_HUMAN
θ value	0.163984 (rank : 54)	NC score	0.010419 (rank : 94)
Query Neighborhood Hits	117	Target Neighborhood Hits	397	Shared Neighborhood Hits	13
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

FOXM1_HUMAN
θ value	0.21417 (rank : 55)	NC score	0.017424 (rank : 74)
Query Neighborhood Hits	117	Target Neighborhood Hits	167	Shared Neighborhood Hits	4
SwissProt Accessions	Q08050, O43258, O43259, O43260, Q4ZGG7, Q9BRL2	Gene names	FOXM1, FKHL16, HFH11, MPP2, WIN
Domain Architecture
Description	Forkhead box protein M1 (Forkhead-related protein FKHL16) (Hepatocyte nuclear factor 3 forkhead homolog 11) (HNF-3/fork-head homolog 11) (HFH-11) (Winged helix factor from INS-1 cells) (M-phase phosphoprotein 2) (MPM-2 reactive phosphoprotein 2) (Transcription factor Trident).

IMUP_HUMAN
θ value	0.279714 (rank : 56)	NC score	0.075869 (rank : 68)
Query Neighborhood Hits	117	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	Q9GZP8, Q96H58, Q9HCR4	Gene names	IMUP, C19orf33
Domain Architecture	No domain graphic available
Description	Immortalization-up-regulated protein (Hepatocyte growth factor activator inhibitor type 2-related small protein) (HAI-2-related small protein) (H2RSP).

AKA12_HUMAN
θ value	0.365318 (rank : 57)	NC score	0.012445 (rank : 86)
Query Neighborhood Hits	117	Target Neighborhood Hits	825	Shared Neighborhood Hits	18
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

WRIP1_HUMAN
θ value	0.47712 (rank : 58)	NC score	0.230493 (rank : 56)
Query Neighborhood Hits	117	Target Neighborhood Hits	100	Shared Neighborhood Hits	51
SwissProt Accessions	Q96S55, Q53EP6, Q59ET8, Q5W0E2, Q5W0E4, Q8WV26, Q9H681, Q9NRJ6	Gene names	WRNIP1, WHIP
Domain Architecture	No domain graphic available
Description	ATPase WRNIP1 (Werner helicase-interacting protein 1).

MAP4_HUMAN
θ value	0.62314 (rank : 59)	NC score	0.016536 (rank : 75)
Query Neighborhood Hits	117	Target Neighborhood Hits	428	Shared Neighborhood Hits	12
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

THNSL_MOUSE
θ value	0.62314 (rank : 60)	NC score	0.131636 (rank : 58)
Query Neighborhood Hits	117	Target Neighborhood Hits	47	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BH55	Gene names	Thnsl1
Domain Architecture	No domain graphic available
Description	Threonine synthase-like 1.

THOC2_HUMAN
θ value	0.62314 (rank : 61)	NC score	0.025397 (rank : 72)
Query Neighborhood Hits	117	Target Neighborhood Hits	337	Shared Neighborhood Hits	14
SwissProt Accessions	Q8NI27, Q9H8I6	Gene names	THOC2, CXorf3
Domain Architecture	No domain graphic available
Description	THO complex subunit 2 (Tho2).

WRIP1_MOUSE
θ value	0.62314 (rank : 62)	NC score	0.229009 (rank : 57)
Query Neighborhood Hits	117	Target Neighborhood Hits	93	Shared Neighborhood Hits	52
SwissProt Accessions	Q91XU0, Q3TCT7, Q6PDF0, Q8BUW5, Q8BWP6, Q8BY55, Q921W3, Q9EQL3	Gene names	Wrnip1, Whip
Domain Architecture	No domain graphic available
Description	ATPase WRNIP1 (Werner helicase-interacting protein 1).

RBBP6_HUMAN
θ value	0.813845 (rank : 63)	NC score	0.016432 (rank : 76)
Query Neighborhood Hits	117	Target Neighborhood Hits	1135	Shared Neighborhood Hits	36
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

BCS1_MOUSE
θ value	1.06291 (rank : 64)	NC score	0.565687 (rank : 50)
Query Neighborhood Hits	117	Target Neighborhood Hits	64	Shared Neighborhood Hits	52
SwissProt Accessions	Q9CZP5	Gene names	Bcs1l
Domain Architecture
Description	Mitochondrial chaperone BCS1 (BCS1-like protein).

SFRS6_HUMAN
θ value	1.06291 (rank : 65)	NC score	0.009501 (rank : 96)
Query Neighborhood Hits	117	Target Neighborhood Hits	247	Shared Neighborhood Hits	9
SwissProt Accessions	Q13247, Q13244, Q13245, Q96J06, Q9UJB8, Q9Y3N7	Gene names	SFRS6, SRP55
Domain Architecture
Description	Splicing factor, arginine/serine-rich 6 (Pre-mRNA-splicing factor SRP55).

LONM_HUMAN
θ value	1.38821 (rank : 66)	NC score	0.408500 (rank : 53)
Query Neighborhood Hits	117	Target Neighborhood Hits	130	Shared Neighborhood Hits	59
SwissProt Accessions	P36776, P36777, Q9UQ95	Gene names	PRSS15
Domain Architecture
Description	Lon protease homolog, mitochondrial precursor (EC 3.4.21.-) (Lon protease-like protein) (LONP) (LONHs).

RFC1_HUMAN
θ value	1.38821 (rank : 67)	NC score	0.120503 (rank : 61)
Query Neighborhood Hits	117	Target Neighborhood Hits	352	Shared Neighborhood Hits	53
SwissProt Accessions	P35251, Q5XKF5, Q6PKU0, Q86V41, Q86V46	Gene names	RFC1, RFC140
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (DNA-binding protein PO-GA).

RFC1_MOUSE
θ value	1.38821 (rank : 68)	NC score	0.130121 (rank : 59)
Query Neighborhood Hits	117	Target Neighborhood Hits	290	Shared Neighborhood Hits	52
SwissProt Accessions	P35601	Gene names	Rfc1, Ibf-1, Recc1
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (A1-P145) (Differentiation- specific element-binding protein) (ISRE-binding protein).

MUC1_MOUSE
θ value	1.81305 (rank : 69)	NC score	0.009611 (rank : 95)
Query Neighborhood Hits	117	Target Neighborhood Hits	388	Shared Neighborhood Hits	8
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

TSH1_MOUSE
θ value	1.81305 (rank : 70)	NC score	0.007115 (rank : 104)
Query Neighborhood Hits	117	Target Neighborhood Hits	675	Shared Neighborhood Hits	10
SwissProt Accessions	Q5DTH5, Q6PE60, Q8VD19, Q9JLD5	Gene names	Tshz1, Kiaa4206, Sdccag33, Tsh1
Domain Architecture	No domain graphic available
Description	Teashirt homolog 1 (Serologically defined colon cancer antigen 3 homolog).

ATN1_HUMAN
θ value	2.36792 (rank : 71)	NC score	0.011360 (rank : 91)
Query Neighborhood Hits	117	Target Neighborhood Hits	676	Shared Neighborhood Hits	15
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

BCS1_HUMAN
θ value	2.36792 (rank : 72)	NC score	0.576281 (rank : 49)
Query Neighborhood Hits	117	Target Neighborhood Hits	61	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Y276, Q7Z2V7	Gene names	BCS1L, BCS1
Domain Architecture
Description	Mitochondrial chaperone BCS1 (BCS1-like protein) (H-BCS1).

CEP35_HUMAN
θ value	2.36792 (rank : 73)	NC score	0.006672 (rank : 105)
Query Neighborhood Hits	117	Target Neighborhood Hits	811	Shared Neighborhood Hits	18
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

SRRM1_HUMAN
θ value	2.36792 (rank : 74)	NC score	0.013903 (rank : 79)
Query Neighborhood Hits	117	Target Neighborhood Hits	690	Shared Neighborhood Hits	16
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

SRRM1_MOUSE
θ value	2.36792 (rank : 75)	NC score	0.013575 (rank : 82)
Query Neighborhood Hits	117	Target Neighborhood Hits	966	Shared Neighborhood Hits	21
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

THNSL_HUMAN
θ value	2.36792 (rank : 76)	NC score	0.120059 (rank : 63)
Query Neighborhood Hits	117	Target Neighborhood Hits	47	Shared Neighborhood Hits	36
SwissProt Accessions	Q8IYQ7, Q5VV21	Gene names	THNSL1
Domain Architecture	No domain graphic available
Description	Threonine synthase-like 1.

ANR26_HUMAN
θ value	3.0926 (rank : 77)	NC score	-0.003015 (rank : 118)
Query Neighborhood Hits	117	Target Neighborhood Hits	1614	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

DEK_HUMAN
θ value	3.0926 (rank : 78)	NC score	0.013156 (rank : 84)
Query Neighborhood Hits	117	Target Neighborhood Hits	199	Shared Neighborhood Hits	7
SwissProt Accessions	P35659, Q5TGV4, Q5TGV5	Gene names	DEK
Domain Architecture	No domain graphic available
Description	Protein DEK.

ENL_HUMAN
θ value	3.0926 (rank : 79)	NC score	0.012888 (rank : 85)
Query Neighborhood Hits	117	Target Neighborhood Hits	305	Shared Neighborhood Hits	12
SwissProt Accessions	Q03111, Q14768	Gene names	MLLT1, ENL, LTG19, YEATS1
Domain Architecture
Description	Protein ENL (YEATS domain-containing protein 1).

SGOL1_HUMAN
θ value	3.0926 (rank : 80)	NC score	0.012098 (rank : 87)
Query Neighborhood Hits	117	Target Neighborhood Hits	62	Shared Neighborhood Hits	3
SwissProt Accessions	Q5FBB7, Q588H5, Q5FBB4, Q5FBB5, Q5FBB6, Q5FBB8, Q8N579, Q8WVL0, Q9BVA8, Q9H275	Gene names	SGOL1, SGO1
Domain Architecture	No domain graphic available
Description	Shugoshin-like 1 (hSgo1) (Serologically defined breast cancer antigen NY-BR-85).

LYAR_MOUSE
θ value	4.03905 (rank : 81)	NC score	0.010858 (rank : 93)
Query Neighborhood Hits	117	Target Neighborhood Hits	153	Shared Neighborhood Hits	9
SwissProt Accessions	Q08288, Q9D9X2	Gene names	Lyar
Domain Architecture	No domain graphic available
Description	Cell growth-regulating nucleolar protein.

M4K4_HUMAN
θ value	4.03905 (rank : 82)	NC score	-0.005856 (rank : 120)
Query Neighborhood Hits	117	Target Neighborhood Hits	1589	Shared Neighborhood Hits	9
SwissProt Accessions	O95819, O75172, Q9NST7	Gene names	MAP4K4, HGK, KIAA0687, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

MCPH1_MOUSE
θ value	4.03905 (rank : 83)	NC score	0.009229 (rank : 100)
Query Neighborhood Hits	117	Target Neighborhood Hits	116	Shared Neighborhood Hits	5
SwissProt Accessions	Q7TT79, Q8BNI9, Q8C9I7	Gene names	Mcph1
Domain Architecture
Description	Microcephalin.

RFC4_HUMAN
θ value	4.03905 (rank : 84)	NC score	0.104778 (rank : 65)
Query Neighborhood Hits	117	Target Neighborhood Hits	64	Shared Neighborhood Hits	39
SwissProt Accessions	P35249, Q6FHX7	Gene names	RFC4
Domain Architecture
Description	Replication factor C subunit 4 (Replication factor C 37 kDa subunit) (RF-C 37 kDa subunit) (RFC37) (Activator 1 37 kDa subunit) (A1 37 kDa subunit).

RTKN_MOUSE
θ value	4.03905 (rank : 85)	NC score	0.014924 (rank : 78)
Query Neighborhood Hits	117	Target Neighborhood Hits	16	Shared Neighborhood Hits	4
SwissProt Accessions	Q8C6B2, Q61192, Q8VIG7	Gene names	Rtkn
Domain Architecture	No domain graphic available
Description	Rhotekin.

TR150_HUMAN
θ value	4.03905 (rank : 86)	NC score	0.011540 (rank : 90)
Query Neighborhood Hits	117	Target Neighborhood Hits	313	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y2W1, Q5VTK6	Gene names	THRAP3, TRAP150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

U2AFM_HUMAN
θ value	4.03905 (rank : 87)	NC score	0.002693 (rank : 112)
Query Neighborhood Hits	117	Target Neighborhood Hits	577	Shared Neighborhood Hits	8
SwissProt Accessions	Q15696	Gene names	ZRSR2, U2AF1-RS2, U2AF1L2, U2AF1RS2
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 2 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 2) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2) (NY-REN-20 antigen).

CBLB_MOUSE
θ value	5.27518 (rank : 88)	NC score	0.005859 (rank : 108)
Query Neighborhood Hits	117	Target Neighborhood Hits	277	Shared Neighborhood Hits	6
SwissProt Accessions	Q3TTA7	Gene names	Cblb
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b).

CIR_MOUSE
θ value	5.27518 (rank : 89)	NC score	0.027201 (rank : 71)
Query Neighborhood Hits	117	Target Neighborhood Hits	255	Shared Neighborhood Hits	10
SwissProt Accessions	Q9DA19, Q3V2N9, Q4KL44, Q52KL9, Q5FW66	Gene names	Cir
Domain Architecture	No domain graphic available
Description	CBF1-interacting corepressor.

DYH5_HUMAN
θ value	5.27518 (rank : 90)	NC score	0.009284 (rank : 98)
Query Neighborhood Hits	117	Target Neighborhood Hits	323	Shared Neighborhood Hits	8
SwissProt Accessions	Q8TE73, Q92860, Q96L74, Q9H5S7, Q9HCG9	Gene names	DNAH5, DNAHC5, KIAA1603
Domain Architecture	No domain graphic available
Description	Ciliary dynein heavy chain 5 (Axonemal beta dynein heavy chain 5) (HL1).

NAB1_HUMAN
θ value	5.27518 (rank : 91)	NC score	0.011953 (rank : 88)
Query Neighborhood Hits	117	Target Neighborhood Hits	33	Shared Neighborhood Hits	4
SwissProt Accessions	Q13506, O75383, O75384, Q6GTU1, Q9UEV1	Gene names	NAB1
Domain Architecture
Description	NGFI-A-binding protein 1 (EGR-1-binding protein 1) (Transcriptional regulatory protein p54).

NPBL_MOUSE
θ value	5.27518 (rank : 92)	NC score	0.011578 (rank : 89)
Query Neighborhood Hits	117	Target Neighborhood Hits	1041	Shared Neighborhood Hits	37
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

RFC4_MOUSE
θ value	5.27518 (rank : 93)	NC score	0.093075 (rank : 66)
Query Neighborhood Hits	117	Target Neighborhood Hits	65	Shared Neighborhood Hits	39
SwissProt Accessions	Q99J62	Gene names	Rfc4
Domain Architecture	No domain graphic available
Description	Replication factor C subunit 4.

SFR12_HUMAN
θ value	5.27518 (rank : 94)	NC score	0.013892 (rank : 80)
Query Neighborhood Hits	117	Target Neighborhood Hits	553	Shared Neighborhood Hits	15
SwissProt Accessions	Q8WXA9, Q86X37	Gene names	SFRS12, SRRP86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86) (Splicing regulatory protein 508) (SRrp508).

SFRS4_MOUSE
θ value	5.27518 (rank : 95)	NC score	0.007487 (rank : 103)
Query Neighborhood Hits	117	Target Neighborhood Hits	406	Shared Neighborhood Hits	15
SwissProt Accessions	Q8VE97, Q9JJC3	Gene names	Sfrs4
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4.

AF9_HUMAN
θ value	6.88961 (rank : 96)	NC score	0.013287 (rank : 83)
Query Neighborhood Hits	117	Target Neighborhood Hits	202	Shared Neighborhood Hits	11
SwissProt Accessions	P42568	Gene names	MLLT3, AF9, YEATS3
Domain Architecture
Description	Protein AF-9 (ALL1 fused gene from chromosome 9 protein) (Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein) (YEATS domain-containing protein 3).

APC_MOUSE
θ value	6.88961 (rank : 97)	NC score	0.007843 (rank : 101)
Query Neighborhood Hits	117	Target Neighborhood Hits	441	Shared Neighborhood Hits	7
SwissProt Accessions	Q61315, Q62044	Gene names	Apc
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC) (mAPC).

BANK1_MOUSE
θ value	6.88961 (rank : 98)	NC score	0.018804 (rank : 73)
Query Neighborhood Hits	117	Target Neighborhood Hits	63	Shared Neighborhood Hits	4
SwissProt Accessions	Q80VH0, Q3U178, Q8BRV6, Q8BRY8	Gene names	Bank1
Domain Architecture	No domain graphic available
Description	B-cell scaffold protein with ankyrin repeats (Protein AVIEF).

BARX2_MOUSE
θ value	6.88961 (rank : 99)	NC score	-0.000507 (rank : 117)
Query Neighborhood Hits	117	Target Neighborhood Hits	335	Shared Neighborhood Hits	3
SwissProt Accessions	O08686	Gene names	Barx2
Domain Architecture
Description	Homeobox protein BarH-like 2.

CTCF_HUMAN
θ value	6.88961 (rank : 100)	NC score	-0.004878 (rank : 119)
Query Neighborhood Hits	117	Target Neighborhood Hits	764	Shared Neighborhood Hits	4
SwissProt Accessions	P49711	Gene names	CTCF
Domain Architecture
Description	Transcriptional repressor CTCF (CCCTC-binding factor) (CTCFL paralog) (11-zinc finger protein).

ERCC6_HUMAN
θ value	6.88961 (rank : 101)	NC score	0.004944 (rank : 109)
Query Neighborhood Hits	117	Target Neighborhood Hits	247	Shared Neighborhood Hits	11
SwissProt Accessions	Q03468	Gene names	ERCC6, CSB
Domain Architecture
Description	DNA excision repair protein ERCC-6 (EC 3.6.1.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB).

GPTC8_HUMAN
θ value	6.88961 (rank : 102)	NC score	0.007798 (rank : 102)
Query Neighborhood Hits	117	Target Neighborhood Hits	366	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

PAWR_HUMAN
θ value	6.88961 (rank : 103)	NC score	0.006455 (rank : 106)
Query Neighborhood Hits	117	Target Neighborhood Hits	252	Shared Neighborhood Hits	5
SwissProt Accessions	Q96IZ0, O75796, Q6FHY9, Q8N700	Gene names	PAWR, PAR4
Domain Architecture	No domain graphic available
Description	PRKC apoptosis WT1 regulator protein (Prostate apoptosis response 4 protein) (Par-4).

TAF3_HUMAN
θ value	6.88961 (rank : 104)	NC score	0.009435 (rank : 97)
Query Neighborhood Hits	117	Target Neighborhood Hits	568	Shared Neighborhood Hits	16
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

ACHA6_MOUSE
θ value	8.99809 (rank : 105)	NC score	-0.000232 (rank : 116)
Query Neighborhood Hits	117	Target Neighborhood Hits	82	Shared Neighborhood Hits	2
SwissProt Accessions	Q9R0W9, Q8K0A7	Gene names	Chrna6, Nica6
Domain Architecture	No domain graphic available
Description	Neuronal acetylcholine receptor protein subunit alpha-6 precursor.

DBNL_HUMAN
θ value	8.99809 (rank : 106)	NC score	0.001402 (rank : 114)
Query Neighborhood Hits	117	Target Neighborhood Hits	244	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UJU6, P84070, Q6IAI8, Q96F30, Q96K74, Q9HBN8, Q9NR72	Gene names	DBNL, CMAP, SH3P7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Drebrin F) (Cervical SH3P7) (HPK1-interacting protein of 55 kDa) (HIP-55) (Cervical mucin-associated protein).

HELZ_HUMAN
θ value	8.99809 (rank : 107)	NC score	0.003505 (rank : 110)
Query Neighborhood Hits	117	Target Neighborhood Hits	198	Shared Neighborhood Hits	6
SwissProt Accessions	P42694	Gene names	HELZ, KIAA0054
Domain Architecture	No domain graphic available
Description	Probable helicase with zinc-finger domain (EC 3.6.1.-).

KAD6_HUMAN
θ value	8.99809 (rank : 108)	NC score	0.107389 (rank : 64)
Query Neighborhood Hits	117	Target Neighborhood Hits	46	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y3D8	Gene names	AK6
Domain Architecture
Description	Adenylate kinase isoenzyme 6 (EC 2.7.4.3) (ATP-AMP transphosphorylase 6).

LIMA1_MOUSE
θ value	8.99809 (rank : 109)	NC score	0.013677 (rank : 81)
Query Neighborhood Hits	117	Target Neighborhood Hits	298	Shared Neighborhood Hits	7
SwissProt Accessions	Q9ERG0, Q9ERG1	Gene names	Lima1, D15Ertd366e, Eplin
Domain Architecture
Description	LIM domain and actin-binding protein 1 (Epithelial protein lost in neoplasm) (mEPLIN).

LRRF1_MOUSE
θ value	8.99809 (rank : 110)	NC score	0.002469 (rank : 113)
Query Neighborhood Hits	117	Target Neighborhood Hits	440	Shared Neighborhood Hits	10
SwissProt Accessions	Q3UZ39, O70323, Q3TS94	Gene names	Lrrfip1, Flap
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 1 (LRR FLII- interacting protein 1) (FLI-LRR-associated protein 1) (Flap-1) (H186 FLAP).

NCOR1_HUMAN
θ value	8.99809 (rank : 111)	NC score	0.003088 (rank : 111)
Query Neighborhood Hits	117	Target Neighborhood Hits	577	Shared Neighborhood Hits	16
SwissProt Accessions	O75376, Q9UPV5, Q9UQ18	Gene names	NCOR1, KIAA1047
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR).

NMDE4_HUMAN
θ value	8.99809 (rank : 112)	NC score	0.000628 (rank : 115)
Query Neighborhood Hits	117	Target Neighborhood Hits	133	Shared Neighborhood Hits	2
SwissProt Accessions	O15399	Gene names	GRIN2D
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 4 precursor (N-methyl D- aspartate receptor subtype 2D) (NR2D) (NMDAR2D) (EB11).

RBBP6_MOUSE
θ value	8.99809 (rank : 113)	NC score	0.014966 (rank : 77)
Query Neighborhood Hits	117	Target Neighborhood Hits	1014	Shared Neighborhood Hits	33
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

RUVB2_HUMAN
θ value	8.99809 (rank : 114)	NC score	0.123872 (rank : 60)
Query Neighborhood Hits	117	Target Neighborhood Hits	43	Shared Neighborhood Hits	38
SwissProt Accessions	Q9Y230, Q6PK27, Q9Y361	Gene names	RUVBL2, TIP48, TIP49B
Domain Architecture
Description	RuvB-like 2 (EC 3.6.1.-) (48 kDa TATA box-binding protein-interacting protein) (48 kDa TBP-interacting protein) (TIP49b) (Repressing pontin 52) (Reptin 52) (51 kDa erythrocyte cytosolic protein) (ECP-51) (TIP60-associated protein 54-beta) (TAP54-beta).

RUVB2_MOUSE
θ value	8.99809 (rank : 115)	NC score	0.120334 (rank : 62)
Query Neighborhood Hits	117	Target Neighborhood Hits	42	Shared Neighborhood Hits	37
SwissProt Accessions	Q9WTM5	Gene names	Ruvbl2
Domain Architecture
Description	RuvB-like 2 (EC 3.6.1.-) (p47 protein).

SFRS4_HUMAN
θ value	8.99809 (rank : 116)	NC score	0.005995 (rank : 107)
Query Neighborhood Hits	117	Target Neighborhood Hits	384	Shared Neighborhood Hits	10
SwissProt Accessions	Q08170, Q5VXP1, Q9BUA4, Q9UEB5	Gene names	SFRS4, SRP75
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4 (Pre-mRNA-splicing factor SRP75) (SRP001LB).

TR150_MOUSE
θ value	8.99809 (rank : 117)	NC score	0.009258 (rank : 99)
Query Neighborhood Hits	117	Target Neighborhood Hits	468	Shared Neighborhood Hits	22
SwissProt Accessions	Q569Z6	Gene names	Thrap3, Trap150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

KAD6_MOUSE
θ value	θ > 10 (rank : 118)	NC score	0.082095 (rank : 67)
Query Neighborhood Hits	117	Target Neighborhood Hits	34	Shared Neighborhood Hits	21
SwissProt Accessions	Q8VCP8	Gene names	Ak6
Domain Architecture	No domain graphic available
Description	Adenylate kinase isoenzyme 6 (EC 2.7.4.3) (ATP-AMP transphosphorylase 6).

RFC5_HUMAN
θ value	θ > 10 (rank : 119)	NC score	0.057366 (rank : 69)
Query Neighborhood Hits	117	Target Neighborhood Hits	60	Shared Neighborhood Hits	32
SwissProt Accessions	P40937	Gene names	RFC5
Domain Architecture
Description	Replication factor C subunit 5 (Replication factor C 36 kDa subunit) (RF-C 36 kDa subunit) (RFC36) (Activator 1 36 kDa subunit) (A1 36 kDa subunit).

RFC5_MOUSE
θ value	θ > 10 (rank : 120)	NC score	0.056612 (rank : 70)
Query Neighborhood Hits	117	Target Neighborhood Hits	58	Shared Neighborhood Hits	33
SwissProt Accessions	Q9D0F6	Gene names	Rfc5
Domain Architecture
Description	Replication factor C subunit 5 (Replication factor C 36 kDa subunit) (RF-C 36 kDa subunit) (RFC36) (Activator 1 36 kDa subunit) (A1 36 kDa subunit).

Hits sorted by NC score

KTNA1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	117	Target Neighborhood Hits	117	Shared Neighborhood Hits	117
SwissProt Accessions	O75449, Q5TFA8, Q5TFA9, Q86VN2, Q9NU52	Gene names	KATNA1
Domain Architecture	No domain graphic available
Description	Katanin p60 ATPase-containing subunit A1 (EC 3.6.4.3) (Katanin p60 subunit A1) (p60 katanin).

KTNA1_MOUSE
NC score	0.997142 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	117	Target Neighborhood Hits	123	Shared Neighborhood Hits	87
SwissProt Accessions	Q9WV86	Gene names	Katna1
Domain Architecture	No domain graphic available
Description	Katanin p60 ATPase-containing subunit A1 (EC 3.6.4.3) (Katanin p60 subunit A1) (p60 katanin) (Lipotransin).

KATL1_MOUSE
NC score	0.995159 (rank : 3)	θ value	2.25013e-176 (rank : 4)
Query Neighborhood Hits	117	Target Neighborhood Hits	77	Shared Neighborhood Hits	67
SwissProt Accessions	Q8K0T4	Gene names	Katnal1
Domain Architecture	No domain graphic available
Description	Katanin p60 ATPase-containing subunit A-like 1 (EC 3.6.4.3) (Katanin p60 subunit A-like 1) (p60 katanin-like 1).

KATL1_HUMAN
NC score	0.995133 (rank : 4)	θ value	2.40406e-178 (rank : 3)
Query Neighborhood Hits	117	Target Neighborhood Hits	80	Shared Neighborhood Hits	67
SwissProt Accessions	Q9BW62	Gene names	KATNAL1
Domain Architecture	No domain graphic available
Description	Katanin p60 ATPase-containing subunit A-like 1 (EC 3.6.4.3) (Katanin p60 subunit A-like 1) (p60 katanin-like 1).

SPAST_HUMAN
NC score	0.962764 (rank : 5)	θ value	6.76295e-64 (rank : 7)
Query Neighborhood Hits	117	Target Neighborhood Hits	100	Shared Neighborhood Hits	61
SwissProt Accessions	Q9UBP0, Q9UPR9	Gene names	SPAST, KIAA1083, SPG4
Domain Architecture
Description	Spastin.

SPAST_MOUSE
NC score	0.961469 (rank : 6)	θ value	7.47731e-63 (rank : 8)
Query Neighborhood Hits	117	Target Neighborhood Hits	138	Shared Neighborhood Hits	65
SwissProt Accessions	Q9QYY8, Q6ZPY6, Q80VE0, Q9CVK0	Gene names	Spast, Kiaa1083, Spg4
Domain Architecture	No domain graphic available
Description	Spastin.

ATAD1_HUMAN
NC score	0.961443 (rank : 7)	θ value	5.20228e-48 (rank : 11)
Query Neighborhood Hits	117	Target Neighborhood Hits	75	Shared Neighborhood Hits	62
SwissProt Accessions	Q8NBU5, Q6P4B9, Q8N3G1, Q8WYR9, Q969Y3	Gene names	ATAD1
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 1.

ATAD1_MOUSE
NC score	0.961443 (rank : 8)	θ value	5.20228e-48 (rank : 12)
Query Neighborhood Hits	117	Target Neighborhood Hits	75	Shared Neighborhood Hits	62
SwissProt Accessions	Q9D5T0, Q3U8V2, Q9D7A4	Gene names	Atad1
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 1.

VPS4B_HUMAN
NC score	0.959997 (rank : 9)	θ value	1.07972e-61 (rank : 10)
Query Neighborhood Hits	117	Target Neighborhood Hits	87	Shared Neighborhood Hits	63
SwissProt Accessions	O75351, Q9GZS7	Gene names	VPS4B, SKD1, VPS42
Domain Architecture
Description	Vacuolar protein sorting-associating protein 4B (Protein SKD1).

VPS4B_MOUSE
NC score	0.959559 (rank : 10)	θ value	7.47731e-63 (rank : 9)
Query Neighborhood Hits	117	Target Neighborhood Hits	86	Shared Neighborhood Hits	62
SwissProt Accessions	P46467, Q91W22, Q9R1C9	Gene names	Vps4b, Skd1
Domain Architecture
Description	Vacuolar protein sorting-associating protein 4B (Protein SKD1).

VPS4A_HUMAN
NC score	0.957970 (rank : 11)	θ value	5.17823e-64 (rank : 5)
Query Neighborhood Hits	117	Target Neighborhood Hits	95	Shared Neighborhood Hits	63
SwissProt Accessions	Q9UN37, Q8TF07, Q9UI03, Q9Y582	Gene names	VPS4A, VPS4
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associating protein 4A (SKD2 protein) (hVPS4) (VPS4-1).

VPS4A_MOUSE
NC score	0.957939 (rank : 12)	θ value	5.17823e-64 (rank : 6)
Query Neighborhood Hits	117	Target Neighborhood Hits	94	Shared Neighborhood Hits	63
SwissProt Accessions	Q8VEJ9, Q3TXT2	Gene names	Vps4a
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associating protein 4A.

TERA_HUMAN
NC score	0.929933 (rank : 13)	θ value	7.03111e-45 (rank : 15)
Query Neighborhood Hits	117	Target Neighborhood Hits	76	Shared Neighborhood Hits	65
SwissProt Accessions	P55072, Q969G7	Gene names	VCP
Domain Architecture
Description	Transitional endoplasmic reticulum ATPase (TER ATPase) (15S Mg(2+)- ATPase p97 subunit) (Valosin-containing protein) (VCP).

TERA_MOUSE
NC score	0.929890 (rank : 14)	θ value	9.18288e-45 (rank : 16)
Query Neighborhood Hits	117	Target Neighborhood Hits	76	Shared Neighborhood Hits	65
SwissProt Accessions	Q01853	Gene names	Vcp
Domain Architecture
Description	Transitional endoplasmic reticulum ATPase (TER ATPase) (15S Mg(2+)- ATPase p97 subunit) (Valosin-containing protein) (VCP).

PRS10_HUMAN
NC score	0.928710 (rank : 15)	θ value	5.21438e-40 (rank : 19)
Query Neighborhood Hits	117	Target Neighborhood Hits	95	Shared Neighborhood Hits	65
SwissProt Accessions	P62333, P49719, Q6IBU3, Q92524	Gene names	PSMC6, SUG2
Domain Architecture
Description	26S protease regulatory subunit S10B (Proteasome subunit p42) (Proteasome 26S subunit ATPase 6).

PRS10_MOUSE
NC score	0.928710 (rank : 16)	θ value	5.21438e-40 (rank : 20)
Query Neighborhood Hits	117	Target Neighborhood Hits	95	Shared Neighborhood Hits	65
SwissProt Accessions	P62334, P49719, Q3TKK1, Q810A6, Q92524, Q9CXH9	Gene names	Psmc6, Sug2
Domain Architecture
Description	26S protease regulatory subunit S10B (Proteasome subunit p42) (Proteasome 26S subunit ATPase 6).

FIGN_MOUSE
NC score	0.928323 (rank : 17)	θ value	1.15895e-47 (rank : 13)
Query Neighborhood Hits	117	Target Neighborhood Hits	165	Shared Neighborhood Hits	59
SwissProt Accessions	Q9ERZ6, Q3TPB0, Q3UP57, Q6PCM0	Gene names	Fign
Domain Architecture	No domain graphic available
Description	Fidgetin.

PRS8_HUMAN
NC score	0.927278 (rank : 18)	θ value	1.2411e-41 (rank : 17)
Query Neighborhood Hits	117	Target Neighborhood Hits	117	Shared Neighborhood Hits	63
SwissProt Accessions	P62195, O35051, O43208, P47210, P52915, P52916	Gene names	PSMC5, SUG1
Domain Architecture
Description	26S protease regulatory subunit 8 (Proteasome 26S subunit ATPase 5) (Proteasome subunit p45) (p45/SUG) (Thyroid hormone receptor- interacting protein 1) (TRIP1).

PRS8_MOUSE
NC score	0.927278 (rank : 19)	θ value	1.2411e-41 (rank : 18)
Query Neighborhood Hits	117	Target Neighborhood Hits	117	Shared Neighborhood Hits	63
SwissProt Accessions	P62196, O35051, P47210, P52915, P52916, Q3UL51, Q9CWN5	Gene names	Psmc5, Sug1
Domain Architecture
Description	26S protease regulatory subunit 8 (Proteasome 26S subunit ATPase 5) (Proteasome subunit p45) (p45/SUG) (mSUG1).

PRS6A_MOUSE
NC score	0.924634 (rank : 20)	θ value	2.42216e-37 (rank : 26)
Query Neighborhood Hits	117	Target Neighborhood Hits	85	Shared Neighborhood Hits	60
SwissProt Accessions	O88685	Gene names	Psmc3, Tbp1
Domain Architecture
Description	26S protease regulatory subunit 6A (Proteasome 26S subunit ATPase 3) (TAT-binding protein 1) (TBP-1).

PRS6A_HUMAN
NC score	0.924449 (rank : 21)	θ value	1.08726e-37 (rank : 25)
Query Neighborhood Hits	117	Target Neighborhood Hits	87	Shared Neighborhood Hits	60
SwissProt Accessions	P17980, Q96HD3	Gene names	PSMC3, TBP1
Domain Architecture
Description	26S protease regulatory subunit 6A (Proteasome 26S subunit ATPase 3) (TAT-binding protein 1) (TBP-1) (Proteasome subunit P50).

FIGN_HUMAN
NC score	0.923864 (rank : 22)	θ value	4.40402e-47 (rank : 14)
Query Neighborhood Hits	117	Target Neighborhood Hits	176	Shared Neighborhood Hits	57
SwissProt Accessions	Q5HY92, Q9H6M5, Q9NVZ9	Gene names	FIGN
Domain Architecture	No domain graphic available
Description	Fidgetin.

PRS4_HUMAN
NC score	0.923488 (rank : 23)	θ value	1.51715e-39 (rank : 21)
Query Neighborhood Hits	117	Target Neighborhood Hits	84	Shared Neighborhood Hits	64
SwissProt Accessions	P62191, P49014, Q03527, Q6IAW0, Q96AZ3	Gene names	PSMC1
Domain Architecture
Description	26S protease regulatory subunit 4 (P26s4) (Proteasome 26S subunit ATPase 1).

PRS4_MOUSE
NC score	0.923488 (rank : 24)	θ value	1.51715e-39 (rank : 22)
Query Neighborhood Hits	117	Target Neighborhood Hits	84	Shared Neighborhood Hits	64
SwissProt Accessions	P62192, P49014, Q03527, Q96AZ3	Gene names	Psmc1
Domain Architecture
Description	26S protease regulatory subunit 4 (P26s4) (Proteasome 26S subunit ATPase 1).

PEX1_HUMAN
NC score	0.922484 (rank : 25)	θ value	2.96089e-35 (rank : 29)
Query Neighborhood Hits	117	Target Neighborhood Hits	98	Shared Neighborhood Hits	62
SwissProt Accessions	O43933, Q96S71, Q96S72, Q96S73, Q99994	Gene names	PEX1
Domain Architecture
Description	Peroxisome biogenesis factor 1 (Peroxin-1) (Peroxisome biogenesis disorder protein 1).

NVL_MOUSE
NC score	0.919901 (rank : 26)	θ value	7.52953e-39 (rank : 24)
Query Neighborhood Hits	117	Target Neighborhood Hits	110	Shared Neighborhood Hits	65
SwissProt Accessions	Q9DBY8, Q3USC4, Q8BW27, Q8K2B5	Gene names	Nvl
Domain Architecture
Description	Nuclear valosin-containing protein-like (Nuclear VCP-like protein) (NVLp).

NVL_HUMAN
NC score	0.919351 (rank : 27)	θ value	5.76516e-39 (rank : 23)
Query Neighborhood Hits	117	Target Neighborhood Hits	112	Shared Neighborhood Hits	66
SwissProt Accessions	O15381, Q96EM7	Gene names	NVL
Domain Architecture
Description	Nuclear valosin-containing protein-like (Nuclear VCP-like protein) (NVLp).

PRS7_HUMAN
NC score	0.918791 (rank : 28)	θ value	1.79631e-32 (rank : 35)
Query Neighborhood Hits	117	Target Neighborhood Hits	66	Shared Neighborhood Hits	61
SwissProt Accessions	P35998	Gene names	PSMC2, MSS1
Domain Architecture
Description	26S protease regulatory subunit 7 (Proteasome 26S subunit ATPase 2) (Protein MSS1).

PRS7_MOUSE
NC score	0.918782 (rank : 29)	θ value	1.79631e-32 (rank : 36)
Query Neighborhood Hits	117	Target Neighborhood Hits	67	Shared Neighborhood Hits	61
SwissProt Accessions	P46471, O08531, Q3TGX5, Q9DBA1	Gene names	Psmc2, Mss1
Domain Architecture
Description	26S protease regulatory subunit 7 (Proteasome 26S subunit ATPase 2) (Protein MSS1).

PRS6B_HUMAN
NC score	0.918038 (rank : 30)	θ value	1.37539e-32 (rank : 34)
Query Neighborhood Hits	117	Target Neighborhood Hits	85	Shared Neighborhood Hits	57
SwissProt Accessions	P43686, Q96FV5, Q9UBM3, Q9UEX3	Gene names	PSMC4, TBP7
Domain Architecture
Description	26S protease regulatory subunit 6B (Proteasome 26S subunit ATPase 4) (MIP224) (MB67-interacting protein) (TAT-binding protein 7) (TBP-7).

PRS6B_MOUSE
NC score	0.916862 (rank : 31)	θ value	6.82597e-32 (rank : 37)
Query Neighborhood Hits	117	Target Neighborhood Hits	89	Shared Neighborhood Hits	57
SwissProt Accessions	P54775	Gene names	Psmc4, Tbp7
Domain Architecture
Description	26S protease regulatory subunit 6B (Proteasome 26S subunit ATPase 4) (MIP224) (MB67-interacting protein) (TAT-binding protein 7) (TBP-7) (CIP21).

PEX6_HUMAN
NC score	0.915081 (rank : 32)	θ value	2.67802e-36 (rank : 28)
Query Neighborhood Hits	117	Target Neighborhood Hits	99	Shared Neighborhood Hits	65
SwissProt Accessions	Q13608, Q8WYQ2, Q99476	Gene names	PEX6, PXAAA1
Domain Architecture
Description	Peroxisome assembly factor 2 (PAF-2) (Peroxisomal-type ATPase 1) (Peroxin-6) (Peroxisomal biogenesis factor 6).

PEX6_MOUSE
NC score	0.914815 (rank : 33)	θ value	7.04741e-37 (rank : 27)
Query Neighborhood Hits	117	Target Neighborhood Hits	94	Shared Neighborhood Hits	63
SwissProt Accessions	Q99LC9, Q6YNQ9	Gene names	Pex6
Domain Architecture	No domain graphic available
Description	Peroxisome assembly factor 2 (PAF-2) (Peroxisomal-type ATPase 1) (Peroxin-6) (Peroxisomal biogenesis factor 6).

YMEL1_MOUSE
NC score	0.903856 (rank : 34)	θ value	1.12514e-34 (rank : 30)
Query Neighborhood Hits	117	Target Neighborhood Hits	76	Shared Neighborhood Hits	60
SwissProt Accessions	O88967, Q7TNN5	Gene names	Yme1l1
Domain Architecture
Description	ATP-dependent metalloprotease YME1L1 (EC 3.4.24.-) (YME1-like protein 1) (ATP-dependent metalloprotease FtsH1).

YMEL1_HUMAN
NC score	0.900325 (rank : 35)	θ value	7.54701e-31 (rank : 40)
Query Neighborhood Hits	117	Target Neighborhood Hits	73	Shared Neighborhood Hits	60
SwissProt Accessions	Q96TA2, Q9H1Q0, Q9UMR9	Gene names	YME1L1, FTSH1, YME1L
Domain Architecture
Description	ATP-dependent metalloprotease YME1L1 (EC 3.4.24.-) (YME1-like protein 1) (ATP-dependent metalloprotease FtsH1) (Meg-4) (Presenilin- associated metalloprotease) (PAMP).

AFG31_MOUSE
NC score	0.898991 (rank : 36)	θ value	1.37539e-32 (rank : 33)
Query Neighborhood Hits	117	Target Neighborhood Hits	74	Shared Neighborhood Hits	62
SwissProt Accessions	Q920A7	Gene names	Afg3l1
Domain Architecture
Description	AFG3-like protein 1 (EC 3.4.24.-).

SPG7_HUMAN
NC score	0.898262 (rank : 37)	θ value	3.74554e-30 (rank : 41)
Query Neighborhood Hits	117	Target Neighborhood Hits	71	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UQ90, O75756, Q96IB0	Gene names	SPG7, CAR, CMAR, PGN
Domain Architecture
Description	Paraplegin (EC 3.4.24.-) (Spastic paraplegia protein 7).

AFG32_HUMAN
NC score	0.893148 (rank : 38)	θ value	3.3877e-31 (rank : 38)
Query Neighborhood Hits	117	Target Neighborhood Hits	72	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Y4W6	Gene names	AFG3L2
Domain Architecture
Description	AFG3-like protein 2 (EC 3.4.24.-) (Paraplegin-like protein).

AFG32_MOUSE
NC score	0.892973 (rank : 39)	θ value	4.42448e-31 (rank : 39)
Query Neighborhood Hits	117	Target Neighborhood Hits	73	Shared Neighborhood Hits	62
SwissProt Accessions	Q8JZQ2	Gene names	Afg3l2
Domain Architecture	No domain graphic available
Description	AFG3-like protein 2 (EC 3.4.24.-).

NSF_HUMAN
NC score	0.879257 (rank : 40)	θ value	5.79196e-23 (rank : 42)
Query Neighborhood Hits	117	Target Neighborhood Hits	74	Shared Neighborhood Hits	64
SwissProt Accessions	P46459, Q9UKZ2	Gene names	NSF
Domain Architecture
Description	Vesicle-fusing ATPase (EC 3.6.4.6) (Vesicular-fusion protein NSF) (N- ethylmaleimide sensitive fusion protein) (NEM-sensitive fusion protein).

NSF_MOUSE
NC score	0.878785 (rank : 41)	θ value	5.79196e-23 (rank : 43)
Query Neighborhood Hits	117	Target Neighborhood Hits	73	Shared Neighborhood Hits	61
SwissProt Accessions	P46460	Gene names	Nsf, Skd2
Domain Architecture
Description	Vesicle-fusing ATPase (EC 3.6.4.6) (Vesicular-fusion protein NSF) (N- ethylmaleimide sensitive fusion protein) (NEM-sensitive fusion protein) (SKD2 protein).

ATAD2_MOUSE
NC score	0.871140 (rank : 42)	θ value	8.06329e-33 (rank : 32)
Query Neighborhood Hits	117	Target Neighborhood Hits	167	Shared Neighborhood Hits	61
SwissProt Accessions	Q8CDM1	Gene names	Atad2
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 2.

ATAD2_HUMAN
NC score	0.853903 (rank : 43)	θ value	4.72714e-33 (rank : 31)
Query Neighborhood Hits	117	Target Neighborhood Hits	322	Shared Neighborhood Hits	64
SwissProt Accessions	Q6PL18, Q658P2, Q68CQ0, Q6PJV6, Q8N890, Q9UHS5	Gene names	ATAD2
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 2.

TRP13_MOUSE
NC score	0.718482 (rank : 44)	θ value	2.13673e-09 (rank : 45)
Query Neighborhood Hits	117	Target Neighborhood Hits	81	Shared Neighborhood Hits	57
SwissProt Accessions	Q3UA06, Q3UQG6, Q9CWW8	Gene names	Trip13
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 13 (Thyroid hormone receptor interactor 13) (Trip-13).

TRP13_HUMAN
NC score	0.717015 (rank : 45)	θ value	2.13673e-09 (rank : 44)
Query Neighborhood Hits	117	Target Neighborhood Hits	81	Shared Neighborhood Hits	58
SwissProt Accessions	Q15645, O15324	Gene names	TRIP13
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 13 (Thyroid hormone receptor interactor 13) (Trip-13) (Human papillomavirus type 16 E1 protein- binding protein) (HPV16 E1 protein-binding protein) (16E1-BP).

ATD3A_HUMAN
NC score	0.638767 (rank : 46)	θ value	1.38499e-08 (rank : 47)
Query Neighborhood Hits	117	Target Neighborhood Hits	248	Shared Neighborhood Hits	63
SwissProt Accessions	Q9NVI7, Q8N275, Q96A50	Gene names	ATAD3A
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 3A.

ATD3B_HUMAN
NC score	0.623496 (rank : 47)	θ value	4.76016e-09 (rank : 46)
Query Neighborhood Hits	117	Target Neighborhood Hits	340	Shared Neighborhood Hits	59
SwissProt Accessions	Q5T9A4, Q6ZRB5, Q9BUK4, Q9ULE7	Gene names	ATAD3B, KIAA1273
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 3B.

ATAD3_MOUSE
NC score	0.614536 (rank : 48)	θ value	2.36244e-08 (rank : 48)
Query Neighborhood Hits	117	Target Neighborhood Hits	326	Shared Neighborhood Hits	62
SwissProt Accessions	Q925I1, Q3UE74, Q69ZM7, Q8C6C6	Gene names	Atad3, Atad3a, Kiaa1273
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 3 (AAA-ATPase TOB3).

BCS1_HUMAN
NC score	0.576281 (rank : 49)	θ value	2.36792 (rank : 72)
Query Neighborhood Hits	117	Target Neighborhood Hits	61	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Y276, Q7Z2V7	Gene names	BCS1L, BCS1
Domain Architecture
Description	Mitochondrial chaperone BCS1 (BCS1-like protein) (H-BCS1).

BCS1_MOUSE
NC score	0.565687 (rank : 50)	θ value	1.06291 (rank : 64)
Query Neighborhood Hits	117	Target Neighborhood Hits	64	Shared Neighborhood Hits	52
SwissProt Accessions	Q9CZP5	Gene names	Bcs1l
Domain Architecture
Description	Mitochondrial chaperone BCS1 (BCS1-like protein).

CLPX_HUMAN
NC score	0.428688 (rank : 51)	θ value	0.00228821 (rank : 50)
Query Neighborhood Hits	117	Target Neighborhood Hits	72	Shared Neighborhood Hits	51
SwissProt Accessions	O76031, Q9H4D9	Gene names	CLPX
Domain Architecture
Description	ATP-dependent Clp protease ATP-binding subunit ClpX-like, mitochondrial precursor.

CLPX_MOUSE
NC score	0.425856 (rank : 52)	θ value	0.00175202 (rank : 49)
Query Neighborhood Hits	117	Target Neighborhood Hits	73	Shared Neighborhood Hits	51
SwissProt Accessions	Q9JHS4, Q9WVD1	Gene names	Clpx
Domain Architecture
Description	ATP-dependent Clp protease ATP-binding subunit ClpX-like, mitochondrial precursor.

LONM_HUMAN
NC score	0.408500 (rank : 53)	θ value	1.38821 (rank : 66)
Query Neighborhood Hits	117	Target Neighborhood Hits	130	Shared Neighborhood Hits	59
SwissProt Accessions	P36776, P36777, Q9UQ95	Gene names	PRSS15
Domain Architecture
Description	Lon protease homolog, mitochondrial precursor (EC 3.4.21.-) (Lon protease-like protein) (LONP) (LONHs).

RUVB1_HUMAN
NC score	0.324907 (rank : 54)	θ value	0.0563607 (rank : 51)
Query Neighborhood Hits	117	Target Neighborhood Hits	78	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Y265, Q9BSX9	Gene names	RUVBL1, NMP238, TIP49, TIP49A
Domain Architecture
Description	RuvB-like 1 (EC 3.6.1.-) (49 kDa TATA box-binding protein-interacting protein) (49 kDa TBP-interacting protein) (TIP49a) (Pontin 52) (Nuclear matrix protein 238) (NMP 238) (54 kDa erythrocyte cytosolic protein) (ECP-54) (TIP60-associated protein 54-alpha) (TAP54-alpha).

RUVB1_MOUSE
NC score	0.324867 (rank : 55)	θ value	0.0563607 (rank : 52)
Query Neighborhood Hits	117	Target Neighborhood Hits	78	Shared Neighborhood Hits	60
SwissProt Accessions	P60122, O35753	Gene names	Ruvbl1, Tip49, Tip49a
Domain Architecture
Description	RuvB-like 1 (EC 3.6.1.-) (49 kDa TATA box-binding protein-interacting protein) (49 kDa TBP-interacting protein) (TIP49a) (Pontin 52) (DNA helicase p50).

WRIP1_HUMAN
NC score	0.230493 (rank : 56)	θ value	0.47712 (rank : 58)
Query Neighborhood Hits	117	Target Neighborhood Hits	100	Shared Neighborhood Hits	51
SwissProt Accessions	Q96S55, Q53EP6, Q59ET8, Q5W0E2, Q5W0E4, Q8WV26, Q9H681, Q9NRJ6	Gene names	WRNIP1, WHIP
Domain Architecture	No domain graphic available
Description	ATPase WRNIP1 (Werner helicase-interacting protein 1).

WRIP1_MOUSE
NC score	0.229009 (rank : 57)	θ value	0.62314 (rank : 62)
Query Neighborhood Hits	117	Target Neighborhood Hits	93	Shared Neighborhood Hits	52
SwissProt Accessions	Q91XU0, Q3TCT7, Q6PDF0, Q8BUW5, Q8BWP6, Q8BY55, Q921W3, Q9EQL3	Gene names	Wrnip1, Whip
Domain Architecture	No domain graphic available
Description	ATPase WRNIP1 (Werner helicase-interacting protein 1).

THNSL_MOUSE
NC score	0.131636 (rank : 58)	θ value	0.62314 (rank : 60)
Query Neighborhood Hits	117	Target Neighborhood Hits	47	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BH55	Gene names	Thnsl1
Domain Architecture	No domain graphic available
Description	Threonine synthase-like 1.

RFC1_MOUSE
NC score	0.130121 (rank : 59)	θ value	1.38821 (rank : 68)
Query Neighborhood Hits	117	Target Neighborhood Hits	290	Shared Neighborhood Hits	52
SwissProt Accessions	P35601	Gene names	Rfc1, Ibf-1, Recc1
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (A1-P145) (Differentiation- specific element-binding protein) (ISRE-binding protein).

RUVB2_HUMAN
NC score	0.123872 (rank : 60)	θ value	8.99809 (rank : 114)
Query Neighborhood Hits	117	Target Neighborhood Hits	43	Shared Neighborhood Hits	38
SwissProt Accessions	Q9Y230, Q6PK27, Q9Y361	Gene names	RUVBL2, TIP48, TIP49B
Domain Architecture
Description	RuvB-like 2 (EC 3.6.1.-) (48 kDa TATA box-binding protein-interacting protein) (48 kDa TBP-interacting protein) (TIP49b) (Repressing pontin 52) (Reptin 52) (51 kDa erythrocyte cytosolic protein) (ECP-51) (TIP60-associated protein 54-beta) (TAP54-beta).

RFC1_HUMAN
NC score	0.120503 (rank : 61)	θ value	1.38821 (rank : 67)
Query Neighborhood Hits	117	Target Neighborhood Hits	352	Shared Neighborhood Hits	53
SwissProt Accessions	P35251, Q5XKF5, Q6PKU0, Q86V41, Q86V46	Gene names	RFC1, RFC140
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (DNA-binding protein PO-GA).

RUVB2_MOUSE
NC score	0.120334 (rank : 62)	θ value	8.99809 (rank : 115)
Query Neighborhood Hits	117	Target Neighborhood Hits	42	Shared Neighborhood Hits	37
SwissProt Accessions	Q9WTM5	Gene names	Ruvbl2
Domain Architecture
Description	RuvB-like 2 (EC 3.6.1.-) (p47 protein).

THNSL_HUMAN
NC score	0.120059 (rank : 63)	θ value	2.36792 (rank : 76)
Query Neighborhood Hits	117	Target Neighborhood Hits	47	Shared Neighborhood Hits	36
SwissProt Accessions	Q8IYQ7, Q5VV21	Gene names	THNSL1
Domain Architecture	No domain graphic available
Description	Threonine synthase-like 1.

KAD6_HUMAN
NC score	0.107389 (rank : 64)	θ value	8.99809 (rank : 108)
Query Neighborhood Hits	117	Target Neighborhood Hits	46	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y3D8	Gene names	AK6
Domain Architecture
Description	Adenylate kinase isoenzyme 6 (EC 2.7.4.3) (ATP-AMP transphosphorylase 6).

RFC4_HUMAN
NC score	0.104778 (rank : 65)	θ value	4.03905 (rank : 84)
Query Neighborhood Hits	117	Target Neighborhood Hits	64	Shared Neighborhood Hits	39
SwissProt Accessions	P35249, Q6FHX7	Gene names	RFC4
Domain Architecture
Description	Replication factor C subunit 4 (Replication factor C 37 kDa subunit) (RF-C 37 kDa subunit) (RFC37) (Activator 1 37 kDa subunit) (A1 37 kDa subunit).

RFC4_MOUSE
NC score	0.093075 (rank : 66)	θ value	5.27518 (rank : 93)
Query Neighborhood Hits	117	Target Neighborhood Hits	65	Shared Neighborhood Hits	39
SwissProt Accessions	Q99J62	Gene names	Rfc4
Domain Architecture	No domain graphic available
Description	Replication factor C subunit 4.

KAD6_MOUSE
NC score	0.082095 (rank : 67)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	117	Target Neighborhood Hits	34	Shared Neighborhood Hits	21
SwissProt Accessions	Q8VCP8	Gene names	Ak6
Domain Architecture	No domain graphic available
Description	Adenylate kinase isoenzyme 6 (EC 2.7.4.3) (ATP-AMP transphosphorylase 6).

IMUP_HUMAN
NC score	0.075869 (rank : 68)	θ value	0.279714 (rank : 56)
Query Neighborhood Hits	117	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	Q9GZP8, Q96H58, Q9HCR4	Gene names	IMUP, C19orf33
Domain Architecture	No domain graphic available
Description	Immortalization-up-regulated protein (Hepatocyte growth factor activator inhibitor type 2-related small protein) (HAI-2-related small protein) (H2RSP).

RFC5_HUMAN
NC score	0.057366 (rank : 69)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	117	Target Neighborhood Hits	60	Shared Neighborhood Hits	32
SwissProt Accessions	P40937	Gene names	RFC5
Domain Architecture
Description	Replication factor C subunit 5 (Replication factor C 36 kDa subunit) (RF-C 36 kDa subunit) (RFC36) (Activator 1 36 kDa subunit) (A1 36 kDa subunit).

RFC5_MOUSE
NC score	0.056612 (rank : 70)	θ value	θ > 10 (rank : 120)
Query Neighborhood Hits	117	Target Neighborhood Hits	58	Shared Neighborhood Hits	33
SwissProt Accessions	Q9D0F6	Gene names	Rfc5
Domain Architecture
Description	Replication factor C subunit 5 (Replication factor C 36 kDa subunit) (RF-C 36 kDa subunit) (RFC36) (Activator 1 36 kDa subunit) (A1 36 kDa subunit).

CIR_MOUSE
NC score	0.027201 (rank : 71)	θ value	5.27518 (rank : 89)
Query Neighborhood Hits	117	Target Neighborhood Hits	255	Shared Neighborhood Hits	10
SwissProt Accessions	Q9DA19, Q3V2N9, Q4KL44, Q52KL9, Q5FW66	Gene names	Cir
Domain Architecture	No domain graphic available
Description	CBF1-interacting corepressor.

THOC2_HUMAN
NC score	0.025397 (rank : 72)	θ value	0.62314 (rank : 61)
Query Neighborhood Hits	117	Target Neighborhood Hits	337	Shared Neighborhood Hits	14
SwissProt Accessions	Q8NI27, Q9H8I6	Gene names	THOC2, CXorf3
Domain Architecture	No domain graphic available
Description	THO complex subunit 2 (Tho2).

BANK1_MOUSE
NC score	0.018804 (rank : 73)	θ value	6.88961 (rank : 98)
Query Neighborhood Hits	117	Target Neighborhood Hits	63	Shared Neighborhood Hits	4
SwissProt Accessions	Q80VH0, Q3U178, Q8BRV6, Q8BRY8	Gene names	Bank1
Domain Architecture	No domain graphic available
Description	B-cell scaffold protein with ankyrin repeats (Protein AVIEF).

FOXM1_HUMAN
NC score	0.017424 (rank : 74)	θ value	0.21417 (rank : 55)
Query Neighborhood Hits	117	Target Neighborhood Hits	167	Shared Neighborhood Hits	4
SwissProt Accessions	Q08050, O43258, O43259, O43260, Q4ZGG7, Q9BRL2	Gene names	FOXM1, FKHL16, HFH11, MPP2, WIN
Domain Architecture
Description	Forkhead box protein M1 (Forkhead-related protein FKHL16) (Hepatocyte nuclear factor 3 forkhead homolog 11) (HNF-3/fork-head homolog 11) (HFH-11) (Winged helix factor from INS-1 cells) (M-phase phosphoprotein 2) (MPM-2 reactive phosphoprotein 2) (Transcription factor Trident).

MAP4_HUMAN
NC score	0.016536 (rank : 75)	θ value	0.62314 (rank : 59)
Query Neighborhood Hits	117	Target Neighborhood Hits	428	Shared Neighborhood Hits	12
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

RBBP6_HUMAN
NC score	0.016432 (rank : 76)	θ value	0.813845 (rank : 63)
Query Neighborhood Hits	117	Target Neighborhood Hits	1135	Shared Neighborhood Hits	36
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

RBBP6_MOUSE
NC score	0.014966 (rank : 77)	θ value	8.99809 (rank : 113)
Query Neighborhood Hits	117	Target Neighborhood Hits	1014	Shared Neighborhood Hits	33
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

RTKN_MOUSE
NC score	0.014924 (rank : 78)	θ value	4.03905 (rank : 85)
Query Neighborhood Hits	117	Target Neighborhood Hits	16	Shared Neighborhood Hits	4
SwissProt Accessions	Q8C6B2, Q61192, Q8VIG7	Gene names	Rtkn
Domain Architecture	No domain graphic available
Description	Rhotekin.

SRRM1_HUMAN
NC score	0.013903 (rank : 79)	θ value	2.36792 (rank : 74)
Query Neighborhood Hits	117	Target Neighborhood Hits	690	Shared Neighborhood Hits	16
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

SFR12_HUMAN
NC score	0.013892 (rank : 80)	θ value	5.27518 (rank : 94)
Query Neighborhood Hits	117	Target Neighborhood Hits	553	Shared Neighborhood Hits	15
SwissProt Accessions	Q8WXA9, Q86X37	Gene names	SFRS12, SRRP86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86) (Splicing regulatory protein 508) (SRrp508).

LIMA1_MOUSE
NC score	0.013677 (rank : 81)	θ value	8.99809 (rank : 109)
Query Neighborhood Hits	117	Target Neighborhood Hits	298	Shared Neighborhood Hits	7
SwissProt Accessions	Q9ERG0, Q9ERG1	Gene names	Lima1, D15Ertd366e, Eplin
Domain Architecture
Description	LIM domain and actin-binding protein 1 (Epithelial protein lost in neoplasm) (mEPLIN).

SRRM1_MOUSE
NC score	0.013575 (rank : 82)	θ value	2.36792 (rank : 75)
Query Neighborhood Hits	117	Target Neighborhood Hits	966	Shared Neighborhood Hits	21
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

AF9_HUMAN
NC score	0.013287 (rank : 83)	θ value	6.88961 (rank : 96)
Query Neighborhood Hits	117	Target Neighborhood Hits	202	Shared Neighborhood Hits	11
SwissProt Accessions	P42568	Gene names	MLLT3, AF9, YEATS3
Domain Architecture
Description	Protein AF-9 (ALL1 fused gene from chromosome 9 protein) (Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein) (YEATS domain-containing protein 3).

DEK_HUMAN
NC score	0.013156 (rank : 84)	θ value	3.0926 (rank : 78)
Query Neighborhood Hits	117	Target Neighborhood Hits	199	Shared Neighborhood Hits	7
SwissProt Accessions	P35659, Q5TGV4, Q5TGV5	Gene names	DEK
Domain Architecture	No domain graphic available
Description	Protein DEK.

ENL_HUMAN
NC score	0.012888 (rank : 85)	θ value	3.0926 (rank : 79)
Query Neighborhood Hits	117	Target Neighborhood Hits	305	Shared Neighborhood Hits	12
SwissProt Accessions	Q03111, Q14768	Gene names	MLLT1, ENL, LTG19, YEATS1
Domain Architecture
Description	Protein ENL (YEATS domain-containing protein 1).

AKA12_HUMAN
NC score	0.012445 (rank : 86)	θ value	0.365318 (rank : 57)
Query Neighborhood Hits	117	Target Neighborhood Hits	825	Shared Neighborhood Hits	18
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

SGOL1_HUMAN
NC score	0.012098 (rank : 87)	θ value	3.0926 (rank : 80)
Query Neighborhood Hits	117	Target Neighborhood Hits	62	Shared Neighborhood Hits	3
SwissProt Accessions	Q5FBB7, Q588H5, Q5FBB4, Q5FBB5, Q5FBB6, Q5FBB8, Q8N579, Q8WVL0, Q9BVA8, Q9H275	Gene names	SGOL1, SGO1
Domain Architecture	No domain graphic available
Description	Shugoshin-like 1 (hSgo1) (Serologically defined breast cancer antigen NY-BR-85).

NAB1_HUMAN
NC score	0.011953 (rank : 88)	θ value	5.27518 (rank : 91)
Query Neighborhood Hits	117	Target Neighborhood Hits	33	Shared Neighborhood Hits	4
SwissProt Accessions	Q13506, O75383, O75384, Q6GTU1, Q9UEV1	Gene names	NAB1
Domain Architecture
Description	NGFI-A-binding protein 1 (EGR-1-binding protein 1) (Transcriptional regulatory protein p54).

NPBL_MOUSE
NC score	0.011578 (rank : 89)	θ value	5.27518 (rank : 92)
Query Neighborhood Hits	117	Target Neighborhood Hits	1041	Shared Neighborhood Hits	37
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

TR150_HUMAN
NC score	0.011540 (rank : 90)	θ value	4.03905 (rank : 86)
Query Neighborhood Hits	117	Target Neighborhood Hits	313	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y2W1, Q5VTK6	Gene names	THRAP3, TRAP150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

ATN1_HUMAN
NC score	0.011360 (rank : 91)	θ value	2.36792 (rank : 71)
Query Neighborhood Hits	117	Target Neighborhood Hits	676	Shared Neighborhood Hits	15
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

CAC1B_MOUSE
NC score	0.010860 (rank : 92)	θ value	0.125558 (rank : 53)
Query Neighborhood Hits	117	Target Neighborhood Hits	351	Shared Neighborhood Hits	7
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

LYAR_MOUSE
NC score	0.010858 (rank : 93)	θ value	4.03905 (rank : 81)
Query Neighborhood Hits	117	Target Neighborhood Hits	153	Shared Neighborhood Hits	9
SwissProt Accessions	Q08288, Q9D9X2	Gene names	Lyar
Domain Architecture	No domain graphic available
Description	Cell growth-regulating nucleolar protein.

CHD3_HUMAN
NC score	0.010419 (rank : 94)	θ value	0.163984 (rank : 54)
Query Neighborhood Hits	117	Target Neighborhood Hits	397	Shared Neighborhood Hits	13
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

MUC1_MOUSE
NC score	0.009611 (rank : 95)	θ value	1.81305 (rank : 69)
Query Neighborhood Hits	117	Target Neighborhood Hits	388	Shared Neighborhood Hits	8
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

SFRS6_HUMAN
NC score	0.009501 (rank : 96)	θ value	1.06291 (rank : 65)
Query Neighborhood Hits	117	Target Neighborhood Hits	247	Shared Neighborhood Hits	9
SwissProt Accessions	Q13247, Q13244, Q13245, Q96J06, Q9UJB8, Q9Y3N7	Gene names	SFRS6, SRP55
Domain Architecture
Description	Splicing factor, arginine/serine-rich 6 (Pre-mRNA-splicing factor SRP55).

TAF3_HUMAN
NC score	0.009435 (rank : 97)	θ value	6.88961 (rank : 104)
Query Neighborhood Hits	117	Target Neighborhood Hits	568	Shared Neighborhood Hits	16
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

DYH5_HUMAN
NC score	0.009284 (rank : 98)	θ value	5.27518 (rank : 90)
Query Neighborhood Hits	117	Target Neighborhood Hits	323	Shared Neighborhood Hits	8
SwissProt Accessions	Q8TE73, Q92860, Q96L74, Q9H5S7, Q9HCG9	Gene names	DNAH5, DNAHC5, KIAA1603
Domain Architecture	No domain graphic available
Description	Ciliary dynein heavy chain 5 (Axonemal beta dynein heavy chain 5) (HL1).

TR150_MOUSE
NC score	0.009258 (rank : 99)	θ value	8.99809 (rank : 117)
Query Neighborhood Hits	117	Target Neighborhood Hits	468	Shared Neighborhood Hits	22
SwissProt Accessions	Q569Z6	Gene names	Thrap3, Trap150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

MCPH1_MOUSE
NC score	0.009229 (rank : 100)	θ value	4.03905 (rank : 83)
Query Neighborhood Hits	117	Target Neighborhood Hits	116	Shared Neighborhood Hits	5
SwissProt Accessions	Q7TT79, Q8BNI9, Q8C9I7	Gene names	Mcph1
Domain Architecture
Description	Microcephalin.

APC_MOUSE
NC score	0.007843 (rank : 101)	θ value	6.88961 (rank : 97)
Query Neighborhood Hits	117	Target Neighborhood Hits	441	Shared Neighborhood Hits	7
SwissProt Accessions	Q61315, Q62044	Gene names	Apc
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC) (mAPC).

GPTC8_HUMAN
NC score	0.007798 (rank : 102)	θ value	6.88961 (rank : 102)
Query Neighborhood Hits	117	Target Neighborhood Hits	366	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

SFRS4_MOUSE
NC score	0.007487 (rank : 103)	θ value	5.27518 (rank : 95)
Query Neighborhood Hits	117	Target Neighborhood Hits	406	Shared Neighborhood Hits	15
SwissProt Accessions	Q8VE97, Q9JJC3	Gene names	Sfrs4
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4.

TSH1_MOUSE
NC score	0.007115 (rank : 104)	θ value	1.81305 (rank : 70)
Query Neighborhood Hits	117	Target Neighborhood Hits	675	Shared Neighborhood Hits	10
SwissProt Accessions	Q5DTH5, Q6PE60, Q8VD19, Q9JLD5	Gene names	Tshz1, Kiaa4206, Sdccag33, Tsh1
Domain Architecture	No domain graphic available
Description	Teashirt homolog 1 (Serologically defined colon cancer antigen 3 homolog).

CEP35_HUMAN
NC score	0.006672 (rank : 105)	θ value	2.36792 (rank : 73)
Query Neighborhood Hits	117	Target Neighborhood Hits	811	Shared Neighborhood Hits	18
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

PAWR_HUMAN
NC score	0.006455 (rank : 106)	θ value	6.88961 (rank : 103)
Query Neighborhood Hits	117	Target Neighborhood Hits	252	Shared Neighborhood Hits	5
SwissProt Accessions	Q96IZ0, O75796, Q6FHY9, Q8N700	Gene names	PAWR, PAR4
Domain Architecture	No domain graphic available
Description	PRKC apoptosis WT1 regulator protein (Prostate apoptosis response 4 protein) (Par-4).

SFRS4_HUMAN
NC score	0.005995 (rank : 107)	θ value	8.99809 (rank : 116)
Query Neighborhood Hits	117	Target Neighborhood Hits	384	Shared Neighborhood Hits	10
SwissProt Accessions	Q08170, Q5VXP1, Q9BUA4, Q9UEB5	Gene names	SFRS4, SRP75
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4 (Pre-mRNA-splicing factor SRP75) (SRP001LB).

CBLB_MOUSE
NC score	0.005859 (rank : 108)	θ value	5.27518 (rank : 88)
Query Neighborhood Hits	117	Target Neighborhood Hits	277	Shared Neighborhood Hits	6
SwissProt Accessions	Q3TTA7	Gene names	Cblb
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b).

ERCC6_HUMAN
NC score	0.004944 (rank : 109)	θ value	6.88961 (rank : 101)
Query Neighborhood Hits	117	Target Neighborhood Hits	247	Shared Neighborhood Hits	11
SwissProt Accessions	Q03468	Gene names	ERCC6, CSB
Domain Architecture
Description	DNA excision repair protein ERCC-6 (EC 3.6.1.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB).

HELZ_HUMAN
NC score	0.003505 (rank : 110)	θ value	8.99809 (rank : 107)
Query Neighborhood Hits	117	Target Neighborhood Hits	198	Shared Neighborhood Hits	6
SwissProt Accessions	P42694	Gene names	HELZ, KIAA0054
Domain Architecture	No domain graphic available
Description	Probable helicase with zinc-finger domain (EC 3.6.1.-).

NCOR1_HUMAN
NC score	0.003088 (rank : 111)	θ value	8.99809 (rank : 111)
Query Neighborhood Hits	117	Target Neighborhood Hits	577	Shared Neighborhood Hits	16
SwissProt Accessions	O75376, Q9UPV5, Q9UQ18	Gene names	NCOR1, KIAA1047
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR).

U2AFM_HUMAN
NC score	0.002693 (rank : 112)	θ value	4.03905 (rank : 87)
Query Neighborhood Hits	117	Target Neighborhood Hits	577	Shared Neighborhood Hits	8
SwissProt Accessions	Q15696	Gene names	ZRSR2, U2AF1-RS2, U2AF1L2, U2AF1RS2
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 2 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 2) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2) (NY-REN-20 antigen).

LRRF1_MOUSE
NC score	0.002469 (rank : 113)	θ value	8.99809 (rank : 110)
Query Neighborhood Hits	117	Target Neighborhood Hits	440	Shared Neighborhood Hits	10
SwissProt Accessions	Q3UZ39, O70323, Q3TS94	Gene names	Lrrfip1, Flap
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 1 (LRR FLII- interacting protein 1) (FLI-LRR-associated protein 1) (Flap-1) (H186 FLAP).

DBNL_HUMAN
NC score	0.001402 (rank : 114)	θ value	8.99809 (rank : 106)
Query Neighborhood Hits	117	Target Neighborhood Hits	244	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UJU6, P84070, Q6IAI8, Q96F30, Q96K74, Q9HBN8, Q9NR72	Gene names	DBNL, CMAP, SH3P7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Drebrin F) (Cervical SH3P7) (HPK1-interacting protein of 55 kDa) (HIP-55) (Cervical mucin-associated protein).

NMDE4_HUMAN
NC score	0.000628 (rank : 115)	θ value	8.99809 (rank : 112)
Query Neighborhood Hits	117	Target Neighborhood Hits	133	Shared Neighborhood Hits	2
SwissProt Accessions	O15399	Gene names	GRIN2D
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 4 precursor (N-methyl D- aspartate receptor subtype 2D) (NR2D) (NMDAR2D) (EB11).

ACHA6_MOUSE
NC score	-0.000232 (rank : 116)	θ value	8.99809 (rank : 105)
Query Neighborhood Hits	117	Target Neighborhood Hits	82	Shared Neighborhood Hits	2
SwissProt Accessions	Q9R0W9, Q8K0A7	Gene names	Chrna6, Nica6
Domain Architecture	No domain graphic available
Description	Neuronal acetylcholine receptor protein subunit alpha-6 precursor.

BARX2_MOUSE
NC score	-0.000507 (rank : 117)	θ value	6.88961 (rank : 99)
Query Neighborhood Hits	117	Target Neighborhood Hits	335	Shared Neighborhood Hits	3
SwissProt Accessions	O08686	Gene names	Barx2
Domain Architecture
Description	Homeobox protein BarH-like 2.

ANR26_HUMAN
NC score	-0.003015 (rank : 118)	θ value	3.0926 (rank : 77)
Query Neighborhood Hits	117	Target Neighborhood Hits	1614	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

CTCF_HUMAN
NC score	-0.004878 (rank : 119)	θ value	6.88961 (rank : 100)
Query Neighborhood Hits	117	Target Neighborhood Hits	764	Shared Neighborhood Hits	4
SwissProt Accessions	P49711	Gene names	CTCF
Domain Architecture
Description	Transcriptional repressor CTCF (CCCTC-binding factor) (CTCFL paralog) (11-zinc finger protein).

M4K4_HUMAN
NC score	-0.005856 (rank : 120)	θ value	4.03905 (rank : 82)
Query Neighborhood Hits	117	Target Neighborhood Hits	1589	Shared Neighborhood Hits	9
SwissProt Accessions	O95819, O75172, Q9NST7	Gene names	MAP4K4, HGK, KIAA0687, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).