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Network neighborhood for query Sequence : PRS6A_MOUSE

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PRS6A_MOUSE
SwissProt Accessions	O88685	Gene names	Psmc3, Tbp1
Domain Architecture
Description	26S protease regulatory subunit 6A (Proteasome 26S subunit ATPase 3) (TAT-binding protein 1) (TBP-1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PRS6A_HUMAN
θ value	0 (rank : 1)	NC score	0.999752 (rank : 2)
Query Neighborhood Hits	85	Target Neighborhood Hits	87	Shared Neighborhood Hits	82
SwissProt Accessions	P17980, Q96HD3	Gene names	PSMC3, TBP1
Domain Architecture
Description	26S protease regulatory subunit 6A (Proteasome 26S subunit ATPase 3) (TAT-binding protein 1) (TBP-1) (Proteasome subunit P50).

PRS6A_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	85	Target Neighborhood Hits	85	Shared Neighborhood Hits	85
SwissProt Accessions	O88685	Gene names	Psmc3, Tbp1
Domain Architecture
Description	26S protease regulatory subunit 6A (Proteasome 26S subunit ATPase 3) (TAT-binding protein 1) (TBP-1).

PRS4_HUMAN
θ value	4.34313e-95 (rank : 3)	NC score	0.988567 (rank : 3)
Query Neighborhood Hits	85	Target Neighborhood Hits	84	Shared Neighborhood Hits	62
SwissProt Accessions	P62191, P49014, Q03527, Q6IAW0, Q96AZ3	Gene names	PSMC1
Domain Architecture
Description	26S protease regulatory subunit 4 (P26s4) (Proteasome 26S subunit ATPase 1).

PRS4_MOUSE
θ value	4.34313e-95 (rank : 4)	NC score	0.988567 (rank : 4)
Query Neighborhood Hits	85	Target Neighborhood Hits	84	Shared Neighborhood Hits	62
SwissProt Accessions	P62192, P49014, Q03527, Q96AZ3	Gene names	Psmc1
Domain Architecture
Description	26S protease regulatory subunit 4 (P26s4) (Proteasome 26S subunit ATPase 1).

PRS8_HUMAN
θ value	1.40038e-85 (rank : 5)	NC score	0.985299 (rank : 5)
Query Neighborhood Hits	85	Target Neighborhood Hits	117	Shared Neighborhood Hits	61
SwissProt Accessions	P62195, O35051, O43208, P47210, P52915, P52916	Gene names	PSMC5, SUG1
Domain Architecture
Description	26S protease regulatory subunit 8 (Proteasome 26S subunit ATPase 5) (Proteasome subunit p45) (p45/SUG) (Thyroid hormone receptor- interacting protein 1) (TRIP1).

PRS8_MOUSE
θ value	1.40038e-85 (rank : 6)	NC score	0.985299 (rank : 6)
Query Neighborhood Hits	85	Target Neighborhood Hits	117	Shared Neighborhood Hits	61
SwissProt Accessions	P62196, O35051, P47210, P52915, P52916, Q3UL51, Q9CWN5	Gene names	Psmc5, Sug1
Domain Architecture
Description	26S protease regulatory subunit 8 (Proteasome 26S subunit ATPase 5) (Proteasome subunit p45) (p45/SUG) (mSUG1).

PRS6B_HUMAN
θ value	3.11973e-85 (rank : 7)	NC score	0.985007 (rank : 7)
Query Neighborhood Hits	85	Target Neighborhood Hits	85	Shared Neighborhood Hits	57
SwissProt Accessions	P43686, Q96FV5, Q9UBM3, Q9UEX3	Gene names	PSMC4, TBP7
Domain Architecture
Description	26S protease regulatory subunit 6B (Proteasome 26S subunit ATPase 4) (MIP224) (MB67-interacting protein) (TAT-binding protein 7) (TBP-7).

PRS6B_MOUSE
θ value	3.44927e-84 (rank : 8)	NC score	0.984601 (rank : 10)
Query Neighborhood Hits	85	Target Neighborhood Hits	89	Shared Neighborhood Hits	57
SwissProt Accessions	P54775	Gene names	Psmc4, Tbp7
Domain Architecture
Description	26S protease regulatory subunit 6B (Proteasome 26S subunit ATPase 4) (MIP224) (MB67-interacting protein) (TAT-binding protein 7) (TBP-7) (CIP21).

PRS7_HUMAN
θ value	3.34088e-79 (rank : 9)	NC score	0.984625 (rank : 8)
Query Neighborhood Hits	85	Target Neighborhood Hits	66	Shared Neighborhood Hits	57
SwissProt Accessions	P35998	Gene names	PSMC2, MSS1
Domain Architecture
Description	26S protease regulatory subunit 7 (Proteasome 26S subunit ATPase 2) (Protein MSS1).

PRS7_MOUSE
θ value	3.34088e-79 (rank : 10)	NC score	0.984614 (rank : 9)
Query Neighborhood Hits	85	Target Neighborhood Hits	67	Shared Neighborhood Hits	57
SwissProt Accessions	P46471, O08531, Q3TGX5, Q9DBA1	Gene names	Psmc2, Mss1
Domain Architecture
Description	26S protease regulatory subunit 7 (Proteasome 26S subunit ATPase 2) (Protein MSS1).

PRS10_HUMAN
θ value	2.92676e-75 (rank : 11)	NC score	0.983995 (rank : 11)
Query Neighborhood Hits	85	Target Neighborhood Hits	95	Shared Neighborhood Hits	62
SwissProt Accessions	P62333, P49719, Q6IBU3, Q92524	Gene names	PSMC6, SUG2
Domain Architecture
Description	26S protease regulatory subunit S10B (Proteasome subunit p42) (Proteasome 26S subunit ATPase 6).

PRS10_MOUSE
θ value	2.92676e-75 (rank : 12)	NC score	0.983995 (rank : 12)
Query Neighborhood Hits	85	Target Neighborhood Hits	95	Shared Neighborhood Hits	62
SwissProt Accessions	P62334, P49719, Q3TKK1, Q810A6, Q92524, Q9CXH9	Gene names	Psmc6, Sug2
Domain Architecture
Description	26S protease regulatory subunit S10B (Proteasome subunit p42) (Proteasome 26S subunit ATPase 6).

TERA_HUMAN
θ value	7.25919e-50 (rank : 13)	NC score	0.949823 (rank : 13)
Query Neighborhood Hits	85	Target Neighborhood Hits	76	Shared Neighborhood Hits	62
SwissProt Accessions	P55072, Q969G7	Gene names	VCP
Domain Architecture
Description	Transitional endoplasmic reticulum ATPase (TER ATPase) (15S Mg(2+)- ATPase p97 subunit) (Valosin-containing protein) (VCP).

TERA_MOUSE
θ value	9.48078e-50 (rank : 14)	NC score	0.949770 (rank : 14)
Query Neighborhood Hits	85	Target Neighborhood Hits	76	Shared Neighborhood Hits	62
SwissProt Accessions	Q01853	Gene names	Vcp
Domain Architecture
Description	Transitional endoplasmic reticulum ATPase (TER ATPase) (15S Mg(2+)- ATPase p97 subunit) (Valosin-containing protein) (VCP).

AFG32_MOUSE
θ value	8.87376e-48 (rank : 15)	NC score	0.939953 (rank : 21)
Query Neighborhood Hits	85	Target Neighborhood Hits	73	Shared Neighborhood Hits	57
SwissProt Accessions	Q8JZQ2	Gene names	Afg3l2
Domain Architecture	No domain graphic available
Description	AFG3-like protein 2 (EC 3.4.24.-).

AFG32_HUMAN
θ value	1.97686e-47 (rank : 16)	NC score	0.940078 (rank : 20)
Query Neighborhood Hits	85	Target Neighborhood Hits	72	Shared Neighborhood Hits	57
SwissProt Accessions	Q9Y4W6	Gene names	AFG3L2
Domain Architecture
Description	AFG3-like protein 2 (EC 3.4.24.-) (Paraplegin-like protein).

AFG31_MOUSE
θ value	3.72821e-46 (rank : 17)	NC score	0.943256 (rank : 17)
Query Neighborhood Hits	85	Target Neighborhood Hits	74	Shared Neighborhood Hits	57
SwissProt Accessions	Q920A7	Gene names	Afg3l1
Domain Architecture
Description	AFG3-like protein 1 (EC 3.4.24.-).

NVL_MOUSE
θ value	1.32601e-43 (rank : 18)	NC score	0.938539 (rank : 22)
Query Neighborhood Hits	85	Target Neighborhood Hits	110	Shared Neighborhood Hits	60
SwissProt Accessions	Q9DBY8, Q3USC4, Q8BW27, Q8K2B5	Gene names	Nvl
Domain Architecture
Description	Nuclear valosin-containing protein-like (Nuclear VCP-like protein) (NVLp).

NVL_HUMAN
θ value	1.12253e-42 (rank : 19)	NC score	0.937692 (rank : 23)
Query Neighborhood Hits	85	Target Neighborhood Hits	112	Shared Neighborhood Hits	61
SwissProt Accessions	O15381, Q96EM7	Gene names	NVL
Domain Architecture
Description	Nuclear valosin-containing protein-like (Nuclear VCP-like protein) (NVLp).

ATAD2_HUMAN
θ value	7.27602e-42 (rank : 20)	NC score	0.878294 (rank : 41)
Query Neighborhood Hits	85	Target Neighborhood Hits	322	Shared Neighborhood Hits	66
SwissProt Accessions	Q6PL18, Q658P2, Q68CQ0, Q6PJV6, Q8N890, Q9UHS5	Gene names	ATAD2
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 2.

PEX6_HUMAN
θ value	2.76489e-41 (rank : 21)	NC score	0.933342 (rank : 25)
Query Neighborhood Hits	85	Target Neighborhood Hits	99	Shared Neighborhood Hits	61
SwissProt Accessions	Q13608, Q8WYQ2, Q99476	Gene names	PEX6, PXAAA1
Domain Architecture
Description	Peroxisome assembly factor 2 (PAF-2) (Peroxisomal-type ATPase 1) (Peroxin-6) (Peroxisomal biogenesis factor 6).

ATAD2_MOUSE
θ value	1.3722e-40 (rank : 22)	NC score	0.894334 (rank : 40)
Query Neighborhood Hits	85	Target Neighborhood Hits	167	Shared Neighborhood Hits	60
SwissProt Accessions	Q8CDM1	Gene names	Atad2
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 2.

SPG7_HUMAN
θ value	1.3722e-40 (rank : 23)	NC score	0.944940 (rank : 16)
Query Neighborhood Hits	85	Target Neighborhood Hits	71	Shared Neighborhood Hits	55
SwissProt Accessions	Q9UQ90, O75756, Q96IB0	Gene names	SPG7, CAR, CMAR, PGN
Domain Architecture
Description	Paraplegin (EC 3.4.24.-) (Spastic paraplegia protein 7).

PEX1_HUMAN
θ value	1.79215e-40 (rank : 24)	NC score	0.945782 (rank : 15)
Query Neighborhood Hits	85	Target Neighborhood Hits	98	Shared Neighborhood Hits	61
SwissProt Accessions	O43933, Q96S71, Q96S72, Q96S73, Q99994	Gene names	PEX1
Domain Architecture
Description	Peroxisome biogenesis factor 1 (Peroxin-1) (Peroxisome biogenesis disorder protein 1).

PEX6_MOUSE
θ value	5.21438e-40 (rank : 25)	NC score	0.932871 (rank : 26)
Query Neighborhood Hits	85	Target Neighborhood Hits	94	Shared Neighborhood Hits	60
SwissProt Accessions	Q99LC9, Q6YNQ9	Gene names	Pex6
Domain Architecture	No domain graphic available
Description	Peroxisome assembly factor 2 (PAF-2) (Peroxisomal-type ATPase 1) (Peroxin-6) (Peroxisomal biogenesis factor 6).

YMEL1_HUMAN
θ value	3.37985e-39 (rank : 26)	NC score	0.932089 (rank : 27)
Query Neighborhood Hits	85	Target Neighborhood Hits	73	Shared Neighborhood Hits	58
SwissProt Accessions	Q96TA2, Q9H1Q0, Q9UMR9	Gene names	YME1L1, FTSH1, YME1L
Domain Architecture
Description	ATP-dependent metalloprotease YME1L1 (EC 3.4.24.-) (YME1-like protein 1) (ATP-dependent metalloprotease FtsH1) (Meg-4) (Presenilin- associated metalloprotease) (PAMP).

YMEL1_MOUSE
θ value	3.37985e-39 (rank : 27)	NC score	0.935608 (rank : 24)
Query Neighborhood Hits	85	Target Neighborhood Hits	76	Shared Neighborhood Hits	58
SwissProt Accessions	O88967, Q7TNN5	Gene names	Yme1l1
Domain Architecture
Description	ATP-dependent metalloprotease YME1L1 (EC 3.4.24.-) (YME1-like protein 1) (ATP-dependent metalloprotease FtsH1).

KATL1_MOUSE
θ value	2.19075e-38 (rank : 28)	NC score	0.927380 (rank : 29)
Query Neighborhood Hits	85	Target Neighborhood Hits	77	Shared Neighborhood Hits	60
SwissProt Accessions	Q8K0T4	Gene names	Katnal1
Domain Architecture	No domain graphic available
Description	Katanin p60 ATPase-containing subunit A-like 1 (EC 3.6.4.3) (Katanin p60 subunit A-like 1) (p60 katanin-like 1).

KATL1_HUMAN
θ value	4.88048e-38 (rank : 29)	NC score	0.927387 (rank : 28)
Query Neighborhood Hits	85	Target Neighborhood Hits	80	Shared Neighborhood Hits	60
SwissProt Accessions	Q9BW62	Gene names	KATNAL1
Domain Architecture	No domain graphic available
Description	Katanin p60 ATPase-containing subunit A-like 1 (EC 3.6.4.3) (Katanin p60 subunit A-like 1) (p60 katanin-like 1).

KTNA1_MOUSE
θ value	8.32485e-38 (rank : 30)	NC score	0.922854 (rank : 31)
Query Neighborhood Hits	85	Target Neighborhood Hits	123	Shared Neighborhood Hits	59
SwissProt Accessions	Q9WV86	Gene names	Katna1
Domain Architecture	No domain graphic available
Description	Katanin p60 ATPase-containing subunit A1 (EC 3.6.4.3) (Katanin p60 subunit A1) (p60 katanin) (Lipotransin).

KTNA1_HUMAN
θ value	2.42216e-37 (rank : 31)	NC score	0.924634 (rank : 30)
Query Neighborhood Hits	85	Target Neighborhood Hits	117	Shared Neighborhood Hits	60
SwissProt Accessions	O75449, Q5TFA8, Q5TFA9, Q86VN2, Q9NU52	Gene names	KATNA1
Domain Architecture	No domain graphic available
Description	Katanin p60 ATPase-containing subunit A1 (EC 3.6.4.3) (Katanin p60 subunit A1) (p60 katanin).

ATAD1_HUMAN
θ value	3.86705e-35 (rank : 32)	NC score	0.940268 (rank : 18)
Query Neighborhood Hits	85	Target Neighborhood Hits	75	Shared Neighborhood Hits	60
SwissProt Accessions	Q8NBU5, Q6P4B9, Q8N3G1, Q8WYR9, Q969Y3	Gene names	ATAD1
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 1.

ATAD1_MOUSE
θ value	3.86705e-35 (rank : 33)	NC score	0.940268 (rank : 19)
Query Neighborhood Hits	85	Target Neighborhood Hits	75	Shared Neighborhood Hits	60
SwissProt Accessions	Q9D5T0, Q3U8V2, Q9D7A4	Gene names	Atad1
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 1.

SPAST_HUMAN
θ value	1.6247e-33 (rank : 34)	NC score	0.919169 (rank : 33)
Query Neighborhood Hits	85	Target Neighborhood Hits	100	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UBP0, Q9UPR9	Gene names	SPAST, KIAA1083, SPG4
Domain Architecture
Description	Spastin.

VPS4B_MOUSE
θ value	2.77131e-33 (rank : 35)	NC score	0.910401 (rank : 37)
Query Neighborhood Hits	85	Target Neighborhood Hits	86	Shared Neighborhood Hits	59
SwissProt Accessions	P46467, Q91W22, Q9R1C9	Gene names	Vps4b, Skd1
Domain Architecture
Description	Vacuolar protein sorting-associating protein 4B (Protein SKD1).

SPAST_MOUSE
θ value	4.72714e-33 (rank : 36)	NC score	0.917412 (rank : 35)
Query Neighborhood Hits	85	Target Neighborhood Hits	138	Shared Neighborhood Hits	57
SwissProt Accessions	Q9QYY8, Q6ZPY6, Q80VE0, Q9CVK0	Gene names	Spast, Kiaa1083, Spg4
Domain Architecture	No domain graphic available
Description	Spastin.

VPS4B_HUMAN
θ value	4.72714e-33 (rank : 37)	NC score	0.910656 (rank : 36)
Query Neighborhood Hits	85	Target Neighborhood Hits	87	Shared Neighborhood Hits	59
SwissProt Accessions	O75351, Q9GZS7	Gene names	VPS4B, SKD1, VPS42
Domain Architecture
Description	Vacuolar protein sorting-associating protein 4B (Protein SKD1).

VPS4A_HUMAN
θ value	1.98606e-31 (rank : 38)	NC score	0.907390 (rank : 38)
Query Neighborhood Hits	85	Target Neighborhood Hits	95	Shared Neighborhood Hits	59
SwissProt Accessions	Q9UN37, Q8TF07, Q9UI03, Q9Y582	Gene names	VPS4A, VPS4
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associating protein 4A (SKD2 protein) (hVPS4) (VPS4-1).

VPS4A_MOUSE
θ value	1.98606e-31 (rank : 39)	NC score	0.907369 (rank : 39)
Query Neighborhood Hits	85	Target Neighborhood Hits	94	Shared Neighborhood Hits	59
SwissProt Accessions	Q8VEJ9, Q3TXT2	Gene names	Vps4a
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associating protein 4A.

NSF_MOUSE
θ value	2.59387e-31 (rank : 40)	NC score	0.919674 (rank : 32)
Query Neighborhood Hits	85	Target Neighborhood Hits	73	Shared Neighborhood Hits	59
SwissProt Accessions	P46460	Gene names	Nsf, Skd2
Domain Architecture
Description	Vesicle-fusing ATPase (EC 3.6.4.6) (Vesicular-fusion protein NSF) (N- ethylmaleimide sensitive fusion protein) (NEM-sensitive fusion protein) (SKD2 protein).

NSF_HUMAN
θ value	4.42448e-31 (rank : 41)	NC score	0.919118 (rank : 34)
Query Neighborhood Hits	85	Target Neighborhood Hits	74	Shared Neighborhood Hits	59
SwissProt Accessions	P46459, Q9UKZ2	Gene names	NSF
Domain Architecture
Description	Vesicle-fusing ATPase (EC 3.6.4.6) (Vesicular-fusion protein NSF) (N- ethylmaleimide sensitive fusion protein) (NEM-sensitive fusion protein).

FIGN_MOUSE
θ value	4.73814e-25 (rank : 42)	NC score	0.873859 (rank : 42)
Query Neighborhood Hits	85	Target Neighborhood Hits	165	Shared Neighborhood Hits	53
SwissProt Accessions	Q9ERZ6, Q3TPB0, Q3UP57, Q6PCM0	Gene names	Fign
Domain Architecture	No domain graphic available
Description	Fidgetin.

FIGN_HUMAN
θ value	8.08199e-25 (rank : 43)	NC score	0.868258 (rank : 43)
Query Neighborhood Hits	85	Target Neighborhood Hits	176	Shared Neighborhood Hits	53
SwissProt Accessions	Q5HY92, Q9H6M5, Q9NVZ9	Gene names	FIGN
Domain Architecture	No domain graphic available
Description	Fidgetin.

ATAD3_MOUSE
θ value	9.59137e-10 (rank : 44)	NC score	0.624299 (rank : 50)
Query Neighborhood Hits	85	Target Neighborhood Hits	326	Shared Neighborhood Hits	66
SwissProt Accessions	Q925I1, Q3UE74, Q69ZM7, Q8C6C6	Gene names	Atad3, Atad3a, Kiaa1273
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 3 (AAA-ATPase TOB3).

ATD3B_HUMAN
θ value	1.63604e-09 (rank : 45)	NC score	0.631098 (rank : 49)
Query Neighborhood Hits	85	Target Neighborhood Hits	340	Shared Neighborhood Hits	65
SwissProt Accessions	Q5T9A4, Q6ZRB5, Q9BUK4, Q9ULE7	Gene names	ATAD3B, KIAA1273
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 3B.

ATD3A_HUMAN
θ value	3.64472e-09 (rank : 46)	NC score	0.642324 (rank : 48)
Query Neighborhood Hits	85	Target Neighborhood Hits	248	Shared Neighborhood Hits	63
SwissProt Accessions	Q9NVI7, Q8N275, Q96A50	Gene names	ATAD3A
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 3A.

BCS1_HUMAN
θ value	3.08544e-08 (rank : 47)	NC score	0.699657 (rank : 44)
Query Neighborhood Hits	85	Target Neighborhood Hits	61	Shared Neighborhood Hits	54
SwissProt Accessions	Q9Y276, Q7Z2V7	Gene names	BCS1L, BCS1
Domain Architecture
Description	Mitochondrial chaperone BCS1 (BCS1-like protein) (H-BCS1).

BCS1_MOUSE
θ value	6.87365e-08 (rank : 48)	NC score	0.690644 (rank : 45)
Query Neighborhood Hits	85	Target Neighborhood Hits	64	Shared Neighborhood Hits	54
SwissProt Accessions	Q9CZP5	Gene names	Bcs1l
Domain Architecture
Description	Mitochondrial chaperone BCS1 (BCS1-like protein).

CLPX_MOUSE
θ value	0.00020696 (rank : 49)	NC score	0.449977 (rank : 52)
Query Neighborhood Hits	85	Target Neighborhood Hits	73	Shared Neighborhood Hits	51
SwissProt Accessions	Q9JHS4, Q9WVD1	Gene names	Clpx
Domain Architecture
Description	ATP-dependent Clp protease ATP-binding subunit ClpX-like, mitochondrial precursor.

CLPX_HUMAN
θ value	0.000270298 (rank : 50)	NC score	0.451823 (rank : 51)
Query Neighborhood Hits	85	Target Neighborhood Hits	72	Shared Neighborhood Hits	51
SwissProt Accessions	O76031, Q9H4D9	Gene names	CLPX
Domain Architecture
Description	ATP-dependent Clp protease ATP-binding subunit ClpX-like, mitochondrial precursor.

TRP13_MOUSE
θ value	0.000786445 (rank : 51)	NC score	0.683967 (rank : 46)
Query Neighborhood Hits	85	Target Neighborhood Hits	81	Shared Neighborhood Hits	57
SwissProt Accessions	Q3UA06, Q3UQG6, Q9CWW8	Gene names	Trip13
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 13 (Thyroid hormone receptor interactor 13) (Trip-13).

TRP13_HUMAN
θ value	0.00102713 (rank : 52)	NC score	0.680171 (rank : 47)
Query Neighborhood Hits	85	Target Neighborhood Hits	81	Shared Neighborhood Hits	57
SwissProt Accessions	Q15645, O15324	Gene names	TRIP13
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 13 (Thyroid hormone receptor interactor 13) (Trip-13) (Human papillomavirus type 16 E1 protein- binding protein) (HPV16 E1 protein-binding protein) (16E1-BP).

RFC5_MOUSE
θ value	0.0431538 (rank : 53)	NC score	0.091967 (rank : 66)
Query Neighborhood Hits	85	Target Neighborhood Hits	58	Shared Neighborhood Hits	32
SwissProt Accessions	Q9D0F6	Gene names	Rfc5
Domain Architecture
Description	Replication factor C subunit 5 (Replication factor C 36 kDa subunit) (RF-C 36 kDa subunit) (RFC36) (Activator 1 36 kDa subunit) (A1 36 kDa subunit).

RFC5_HUMAN
θ value	0.0563607 (rank : 54)	NC score	0.090599 (rank : 68)
Query Neighborhood Hits	85	Target Neighborhood Hits	60	Shared Neighborhood Hits	30
SwissProt Accessions	P40937	Gene names	RFC5
Domain Architecture
Description	Replication factor C subunit 5 (Replication factor C 36 kDa subunit) (RF-C 36 kDa subunit) (RFC36) (Activator 1 36 kDa subunit) (A1 36 kDa subunit).

WRIP1_HUMAN
θ value	0.125558 (rank : 55)	NC score	0.249560 (rank : 57)
Query Neighborhood Hits	85	Target Neighborhood Hits	100	Shared Neighborhood Hits	50
SwissProt Accessions	Q96S55, Q53EP6, Q59ET8, Q5W0E2, Q5W0E4, Q8WV26, Q9H681, Q9NRJ6	Gene names	WRNIP1, WHIP
Domain Architecture	No domain graphic available
Description	ATPase WRNIP1 (Werner helicase-interacting protein 1).

RUVB1_HUMAN
θ value	0.163984 (rank : 56)	NC score	0.308706 (rank : 54)
Query Neighborhood Hits	85	Target Neighborhood Hits	78	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Y265, Q9BSX9	Gene names	RUVBL1, NMP238, TIP49, TIP49A
Domain Architecture
Description	RuvB-like 1 (EC 3.6.1.-) (49 kDa TATA box-binding protein-interacting protein) (49 kDa TBP-interacting protein) (TIP49a) (Pontin 52) (Nuclear matrix protein 238) (NMP 238) (54 kDa erythrocyte cytosolic protein) (ECP-54) (TIP60-associated protein 54-alpha) (TAP54-alpha).

RUVB1_MOUSE
θ value	0.163984 (rank : 57)	NC score	0.308667 (rank : 55)
Query Neighborhood Hits	85	Target Neighborhood Hits	78	Shared Neighborhood Hits	56
SwissProt Accessions	P60122, O35753	Gene names	Ruvbl1, Tip49, Tip49a
Domain Architecture
Description	RuvB-like 1 (EC 3.6.1.-) (49 kDa TATA box-binding protein-interacting protein) (49 kDa TBP-interacting protein) (TIP49a) (Pontin 52) (DNA helicase p50).

SMC2_HUMAN
θ value	0.279714 (rank : 58)	NC score	0.014766 (rank : 76)
Query Neighborhood Hits	85	Target Neighborhood Hits	1405	Shared Neighborhood Hits	24
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

WRIP1_MOUSE
θ value	0.279714 (rank : 59)	NC score	0.252233 (rank : 56)
Query Neighborhood Hits	85	Target Neighborhood Hits	93	Shared Neighborhood Hits	49
SwissProt Accessions	Q91XU0, Q3TCT7, Q6PDF0, Q8BUW5, Q8BWP6, Q8BY55, Q921W3, Q9EQL3	Gene names	Wrnip1, Whip
Domain Architecture	No domain graphic available
Description	ATPase WRNIP1 (Werner helicase-interacting protein 1).

TAXB1_HUMAN
θ value	0.62314 (rank : 60)	NC score	0.010259 (rank : 80)
Query Neighborhood Hits	85	Target Neighborhood Hits	829	Shared Neighborhood Hits	19
SwissProt Accessions	Q86VP1, O60398, O95770, Q13311, Q9BQG5, Q9UI88	Gene names	TAX1BP1, T6BP
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 1 (TRAF6-binding protein).

LONM_HUMAN
θ value	0.813845 (rank : 61)	NC score	0.419752 (rank : 53)
Query Neighborhood Hits	85	Target Neighborhood Hits	130	Shared Neighborhood Hits	58
SwissProt Accessions	P36776, P36777, Q9UQ95	Gene names	PRSS15
Domain Architecture
Description	Lon protease homolog, mitochondrial precursor (EC 3.4.21.-) (Lon protease-like protein) (LONP) (LONHs).

SMC2_MOUSE
θ value	0.813845 (rank : 62)	NC score	0.013133 (rank : 77)
Query Neighborhood Hits	85	Target Neighborhood Hits	1131	Shared Neighborhood Hits	19
SwissProt Accessions	Q8CG48, Q61076, Q9CS17, Q9CSD8	Gene names	Smc2l1, Cape, Fin16, Smc2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (XCAP-E homolog) (FGF-inducible protein 16).

CE290_HUMAN
θ value	1.38821 (rank : 63)	NC score	0.012913 (rank : 78)
Query Neighborhood Hits	85	Target Neighborhood Hits	1553	Shared Neighborhood Hits	25
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

CCD13_HUMAN
θ value	2.36792 (rank : 64)	NC score	0.006655 (rank : 83)
Query Neighborhood Hits	85	Target Neighborhood Hits	721	Shared Neighborhood Hits	18
SwissProt Accessions	Q8IYE1	Gene names	CCDC13
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 13.

NAB1_HUMAN
θ value	2.36792 (rank : 65)	NC score	0.021343 (rank : 74)
Query Neighborhood Hits	85	Target Neighborhood Hits	33	Shared Neighborhood Hits	7
SwissProt Accessions	Q13506, O75383, O75384, Q6GTU1, Q9UEV1	Gene names	NAB1
Domain Architecture
Description	NGFI-A-binding protein 1 (EGR-1-binding protein 1) (Transcriptional regulatory protein p54).

CENPF_HUMAN
θ value	3.0926 (rank : 66)	NC score	0.004827 (rank : 88)
Query Neighborhood Hits	85	Target Neighborhood Hits	1932	Shared Neighborhood Hits	23
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

MYH14_HUMAN
θ value	3.0926 (rank : 67)	NC score	0.001982 (rank : 92)
Query Neighborhood Hits	85	Target Neighborhood Hits	995	Shared Neighborhood Hits	18
SwissProt Accessions	Q7Z406, Q5CZ75, Q6XYE4, Q76B62, Q8WV23, Q96I22, Q9BT27, Q9BW35, Q9H882	Gene names	MYH14, KIAA2034
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

NAB1_MOUSE
θ value	3.0926 (rank : 68)	NC score	0.018726 (rank : 75)
Query Neighborhood Hits	85	Target Neighborhood Hits	19	Shared Neighborhood Hits	4
SwissProt Accessions	Q61122	Gene names	Nab1
Domain Architecture
Description	NGFI-A-binding protein 1 (EGR-1-binding protein 1).

RBP22_HUMAN
θ value	3.0926 (rank : 69)	NC score	0.009059 (rank : 82)
Query Neighborhood Hits	85	Target Neighborhood Hits	165	Shared Neighborhood Hits	8
SwissProt Accessions	Q53T03, Q53QN2, Q59GM7	Gene names	RANBP2L2
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 2 (RanBP2L2).

SMC4_MOUSE
θ value	3.0926 (rank : 70)	NC score	0.009705 (rank : 81)
Query Neighborhood Hits	85	Target Neighborhood Hits	830	Shared Neighborhood Hits	18
SwissProt Accessions	Q8CG47, Q8BTS7, Q8BTY9, Q99K21	Gene names	Smc4l1, Capc, Smc4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (XCAP-C homolog).

TRIPB_HUMAN
θ value	3.0926 (rank : 71)	NC score	0.006110 (rank : 85)
Query Neighborhood Hits	85	Target Neighborhood Hits	1587	Shared Neighborhood Hits	25
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

DOCK8_HUMAN
θ value	5.27518 (rank : 72)	NC score	0.006415 (rank : 84)
Query Neighborhood Hits	85	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NF50, Q3MV16, Q5JPJ1, Q8TEP1, Q8WUY2, Q9BYJ5, Q9H1Q2, Q9H1Q3, Q9H308, Q9H7P2	Gene names	DOCK8
Domain Architecture	No domain graphic available
Description	Dedicator of cytokinesis protein 8.

OPTN_MOUSE
θ value	5.27518 (rank : 73)	NC score	0.005750 (rank : 86)
Query Neighborhood Hits	85	Target Neighborhood Hits	1120	Shared Neighborhood Hits	25
SwissProt Accessions	Q8K3K8	Gene names	Optn
Domain Architecture	No domain graphic available
Description	Optineurin.

PEPL_HUMAN
θ value	5.27518 (rank : 74)	NC score	0.003053 (rank : 90)
Query Neighborhood Hits	85	Target Neighborhood Hits	1141	Shared Neighborhood Hits	18
SwissProt Accessions	O60437, O60314, O60454	Gene names	PPL, KIAA0568
Domain Architecture
Description	Periplakin (195 kDa cornified envelope precursor protein) (190 kDa paraneoplastic pemphigus antigen).

RFC4_HUMAN
θ value	5.27518 (rank : 75)	NC score	0.111798 (rank : 58)
Query Neighborhood Hits	85	Target Neighborhood Hits	64	Shared Neighborhood Hits	40
SwissProt Accessions	P35249, Q6FHX7	Gene names	RFC4
Domain Architecture
Description	Replication factor C subunit 4 (Replication factor C 37 kDa subunit) (RF-C 37 kDa subunit) (RFC37) (Activator 1 37 kDa subunit) (A1 37 kDa subunit).

RFC4_MOUSE
θ value	5.27518 (rank : 76)	NC score	0.100818 (rank : 62)
Query Neighborhood Hits	85	Target Neighborhood Hits	65	Shared Neighborhood Hits	40
SwissProt Accessions	Q99J62	Gene names	Rfc4
Domain Architecture	No domain graphic available
Description	Replication factor C subunit 4.

SPAG5_MOUSE
θ value	5.27518 (rank : 77)	NC score	0.012032 (rank : 79)
Query Neighborhood Hits	85	Target Neighborhood Hits	612	Shared Neighborhood Hits	20
SwissProt Accessions	Q7TME2, Q8CH61	Gene names	Spag5
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 5 (Mastrin) (Mitotic spindle-associated protein p126) (MAP126).

EEA1_HUMAN
θ value	6.88961 (rank : 78)	NC score	0.002291 (rank : 91)
Query Neighborhood Hits	85	Target Neighborhood Hits	1796	Shared Neighborhood Hits	21
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

KINH_HUMAN
θ value	6.88961 (rank : 79)	NC score	0.001843 (rank : 93)
Query Neighborhood Hits	85	Target Neighborhood Hits	1231	Shared Neighborhood Hits	22
SwissProt Accessions	P33176, Q5VZ85	Gene names	KIF5B, KNS, KNS1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

NAF1_MOUSE
θ value	6.88961 (rank : 80)	NC score	0.003618 (rank : 89)
Query Neighborhood Hits	85	Target Neighborhood Hits	852	Shared Neighborhood Hits	18
SwissProt Accessions	Q9WUU8, Q922A9, Q922F7, Q9EPP8, Q9R0X3	Gene names	Tnip1, Abin, Naf1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (A20- binding inhibitor of NF-kappa-B activation) (ABIN) (Virion-associated nuclear shuttling protein) (VAN) (mVAN).

RENT1_MOUSE
θ value	6.88961 (rank : 81)	NC score	0.025028 (rank : 72)
Query Neighborhood Hits	85	Target Neighborhood Hits	54	Shared Neighborhood Hits	11
SwissProt Accessions	Q9EPU0, Q99PR4	Gene names	Upf1, Rent1
Domain Architecture
Description	Regulator of nonsense transcripts 1 (EC 3.6.1.-) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up- frameshift suppressor 1 homolog) (mUpf1).

MDN1_HUMAN
θ value	8.99809 (rank : 82)	NC score	0.036232 (rank : 71)
Query Neighborhood Hits	85	Target Neighborhood Hits	662	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

MORC4_MOUSE
θ value	8.99809 (rank : 83)	NC score	0.005712 (rank : 87)
Query Neighborhood Hits	85	Target Neighborhood Hits	235	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BMD7, Q4KMM6, Q8BX95, Q9CS96	Gene names	Morc4, Zcwcc2
Domain Architecture	No domain graphic available
Description	MORC family CW-type zinc finger protein 4 (Zinc finger CW-type coiled- coil domain protein 2).

RENT1_HUMAN
θ value	8.99809 (rank : 84)	NC score	0.023447 (rank : 73)
Query Neighborhood Hits	85	Target Neighborhood Hits	51	Shared Neighborhood Hits	11
SwissProt Accessions	Q92900, O00239, O43343, Q86Z25, Q92842	Gene names	UPF1, KIAA0221, RENT1
Domain Architecture
Description	Regulator of nonsense transcripts 1 (EC 3.6.1.-) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up- frameshift suppressor 1 homolog) (hUpf1).

UACA_HUMAN
θ value	8.99809 (rank : 85)	NC score	0.000328 (rank : 94)
Query Neighborhood Hits	85	Target Neighborhood Hits	1622	Shared Neighborhood Hits	24
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

KAD6_HUMAN
θ value	θ > 10 (rank : 86)	NC score	0.090932 (rank : 67)
Query Neighborhood Hits	85	Target Neighborhood Hits	46	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y3D8	Gene names	AK6
Domain Architecture
Description	Adenylate kinase isoenzyme 6 (EC 2.7.4.3) (ATP-AMP transphosphorylase 6).

KAD6_MOUSE
θ value	θ > 10 (rank : 87)	NC score	0.070425 (rank : 69)
Query Neighborhood Hits	85	Target Neighborhood Hits	34	Shared Neighborhood Hits	19
SwissProt Accessions	Q8VCP8	Gene names	Ak6
Domain Architecture	No domain graphic available
Description	Adenylate kinase isoenzyme 6 (EC 2.7.4.3) (ATP-AMP transphosphorylase 6).

RFC1_HUMAN
θ value	θ > 10 (rank : 88)	NC score	0.098855 (rank : 64)
Query Neighborhood Hits	85	Target Neighborhood Hits	352	Shared Neighborhood Hits	45
SwissProt Accessions	P35251, Q5XKF5, Q6PKU0, Q86V41, Q86V46	Gene names	RFC1, RFC140
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (DNA-binding protein PO-GA).

RFC1_MOUSE
θ value	θ > 10 (rank : 89)	NC score	0.111189 (rank : 59)
Query Neighborhood Hits	85	Target Neighborhood Hits	290	Shared Neighborhood Hits	46
SwissProt Accessions	P35601	Gene names	Rfc1, Ibf-1, Recc1
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (A1-P145) (Differentiation- specific element-binding protein) (ISRE-binding protein).

RFC2_HUMAN
θ value	θ > 10 (rank : 90)	NC score	0.050582 (rank : 70)
Query Neighborhood Hits	85	Target Neighborhood Hits	46	Shared Neighborhood Hits	20
SwissProt Accessions	P35250, P32846, Q9BU93	Gene names	RFC2
Domain Architecture
Description	Replication factor C subunit 2 (Replication factor C 40 kDa subunit) (RF-C 40 kDa subunit) (RFC40) (Activator 1 40 kDa subunit) (A1 40 kDa subunit).

RUVB2_HUMAN
θ value	θ > 10 (rank : 91)	NC score	0.110868 (rank : 60)
Query Neighborhood Hits	85	Target Neighborhood Hits	43	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Y230, Q6PK27, Q9Y361	Gene names	RUVBL2, TIP48, TIP49B
Domain Architecture
Description	RuvB-like 2 (EC 3.6.1.-) (48 kDa TATA box-binding protein-interacting protein) (48 kDa TBP-interacting protein) (TIP49b) (Repressing pontin 52) (Reptin 52) (51 kDa erythrocyte cytosolic protein) (ECP-51) (TIP60-associated protein 54-beta) (TAP54-beta).

RUVB2_MOUSE
θ value	θ > 10 (rank : 92)	NC score	0.108271 (rank : 61)
Query Neighborhood Hits	85	Target Neighborhood Hits	42	Shared Neighborhood Hits	36
SwissProt Accessions	Q9WTM5	Gene names	Ruvbl2
Domain Architecture
Description	RuvB-like 2 (EC 3.6.1.-) (p47 protein).

THNSL_HUMAN
θ value	θ > 10 (rank : 93)	NC score	0.095754 (rank : 65)
Query Neighborhood Hits	85	Target Neighborhood Hits	47	Shared Neighborhood Hits	31
SwissProt Accessions	Q8IYQ7, Q5VV21	Gene names	THNSL1
Domain Architecture	No domain graphic available
Description	Threonine synthase-like 1.

THNSL_MOUSE
θ value	θ > 10 (rank : 94)	NC score	0.099048 (rank : 63)
Query Neighborhood Hits	85	Target Neighborhood Hits	47	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BH55	Gene names	Thnsl1
Domain Architecture	No domain graphic available
Description	Threonine synthase-like 1.

Hits sorted by NC score

PRS6A_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	85	Target Neighborhood Hits	85	Shared Neighborhood Hits	85
SwissProt Accessions	O88685	Gene names	Psmc3, Tbp1
Domain Architecture
Description	26S protease regulatory subunit 6A (Proteasome 26S subunit ATPase 3) (TAT-binding protein 1) (TBP-1).

PRS6A_HUMAN
NC score	0.999752 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	85	Target Neighborhood Hits	87	Shared Neighborhood Hits	82
SwissProt Accessions	P17980, Q96HD3	Gene names	PSMC3, TBP1
Domain Architecture
Description	26S protease regulatory subunit 6A (Proteasome 26S subunit ATPase 3) (TAT-binding protein 1) (TBP-1) (Proteasome subunit P50).

PRS4_HUMAN
NC score	0.988567 (rank : 3)	θ value	4.34313e-95 (rank : 3)
Query Neighborhood Hits	85	Target Neighborhood Hits	84	Shared Neighborhood Hits	62
SwissProt Accessions	P62191, P49014, Q03527, Q6IAW0, Q96AZ3	Gene names	PSMC1
Domain Architecture
Description	26S protease regulatory subunit 4 (P26s4) (Proteasome 26S subunit ATPase 1).

PRS4_MOUSE
NC score	0.988567 (rank : 4)	θ value	4.34313e-95 (rank : 4)
Query Neighborhood Hits	85	Target Neighborhood Hits	84	Shared Neighborhood Hits	62
SwissProt Accessions	P62192, P49014, Q03527, Q96AZ3	Gene names	Psmc1
Domain Architecture
Description	26S protease regulatory subunit 4 (P26s4) (Proteasome 26S subunit ATPase 1).

PRS8_HUMAN
NC score	0.985299 (rank : 5)	θ value	1.40038e-85 (rank : 5)
Query Neighborhood Hits	85	Target Neighborhood Hits	117	Shared Neighborhood Hits	61
SwissProt Accessions	P62195, O35051, O43208, P47210, P52915, P52916	Gene names	PSMC5, SUG1
Domain Architecture
Description	26S protease regulatory subunit 8 (Proteasome 26S subunit ATPase 5) (Proteasome subunit p45) (p45/SUG) (Thyroid hormone receptor- interacting protein 1) (TRIP1).

PRS8_MOUSE
NC score	0.985299 (rank : 6)	θ value	1.40038e-85 (rank : 6)
Query Neighborhood Hits	85	Target Neighborhood Hits	117	Shared Neighborhood Hits	61
SwissProt Accessions	P62196, O35051, P47210, P52915, P52916, Q3UL51, Q9CWN5	Gene names	Psmc5, Sug1
Domain Architecture
Description	26S protease regulatory subunit 8 (Proteasome 26S subunit ATPase 5) (Proteasome subunit p45) (p45/SUG) (mSUG1).

PRS6B_HUMAN
NC score	0.985007 (rank : 7)	θ value	3.11973e-85 (rank : 7)
Query Neighborhood Hits	85	Target Neighborhood Hits	85	Shared Neighborhood Hits	57
SwissProt Accessions	P43686, Q96FV5, Q9UBM3, Q9UEX3	Gene names	PSMC4, TBP7
Domain Architecture
Description	26S protease regulatory subunit 6B (Proteasome 26S subunit ATPase 4) (MIP224) (MB67-interacting protein) (TAT-binding protein 7) (TBP-7).

PRS7_HUMAN
NC score	0.984625 (rank : 8)	θ value	3.34088e-79 (rank : 9)
Query Neighborhood Hits	85	Target Neighborhood Hits	66	Shared Neighborhood Hits	57
SwissProt Accessions	P35998	Gene names	PSMC2, MSS1
Domain Architecture
Description	26S protease regulatory subunit 7 (Proteasome 26S subunit ATPase 2) (Protein MSS1).

PRS7_MOUSE
NC score	0.984614 (rank : 9)	θ value	3.34088e-79 (rank : 10)
Query Neighborhood Hits	85	Target Neighborhood Hits	67	Shared Neighborhood Hits	57
SwissProt Accessions	P46471, O08531, Q3TGX5, Q9DBA1	Gene names	Psmc2, Mss1
Domain Architecture
Description	26S protease regulatory subunit 7 (Proteasome 26S subunit ATPase 2) (Protein MSS1).

PRS6B_MOUSE
NC score	0.984601 (rank : 10)	θ value	3.44927e-84 (rank : 8)
Query Neighborhood Hits	85	Target Neighborhood Hits	89	Shared Neighborhood Hits	57
SwissProt Accessions	P54775	Gene names	Psmc4, Tbp7
Domain Architecture
Description	26S protease regulatory subunit 6B (Proteasome 26S subunit ATPase 4) (MIP224) (MB67-interacting protein) (TAT-binding protein 7) (TBP-7) (CIP21).

PRS10_HUMAN
NC score	0.983995 (rank : 11)	θ value	2.92676e-75 (rank : 11)
Query Neighborhood Hits	85	Target Neighborhood Hits	95	Shared Neighborhood Hits	62
SwissProt Accessions	P62333, P49719, Q6IBU3, Q92524	Gene names	PSMC6, SUG2
Domain Architecture
Description	26S protease regulatory subunit S10B (Proteasome subunit p42) (Proteasome 26S subunit ATPase 6).

PRS10_MOUSE
NC score	0.983995 (rank : 12)	θ value	2.92676e-75 (rank : 12)
Query Neighborhood Hits	85	Target Neighborhood Hits	95	Shared Neighborhood Hits	62
SwissProt Accessions	P62334, P49719, Q3TKK1, Q810A6, Q92524, Q9CXH9	Gene names	Psmc6, Sug2
Domain Architecture
Description	26S protease regulatory subunit S10B (Proteasome subunit p42) (Proteasome 26S subunit ATPase 6).

TERA_HUMAN
NC score	0.949823 (rank : 13)	θ value	7.25919e-50 (rank : 13)
Query Neighborhood Hits	85	Target Neighborhood Hits	76	Shared Neighborhood Hits	62
SwissProt Accessions	P55072, Q969G7	Gene names	VCP
Domain Architecture
Description	Transitional endoplasmic reticulum ATPase (TER ATPase) (15S Mg(2+)- ATPase p97 subunit) (Valosin-containing protein) (VCP).

TERA_MOUSE
NC score	0.949770 (rank : 14)	θ value	9.48078e-50 (rank : 14)
Query Neighborhood Hits	85	Target Neighborhood Hits	76	Shared Neighborhood Hits	62
SwissProt Accessions	Q01853	Gene names	Vcp
Domain Architecture
Description	Transitional endoplasmic reticulum ATPase (TER ATPase) (15S Mg(2+)- ATPase p97 subunit) (Valosin-containing protein) (VCP).

PEX1_HUMAN
NC score	0.945782 (rank : 15)	θ value	1.79215e-40 (rank : 24)
Query Neighborhood Hits	85	Target Neighborhood Hits	98	Shared Neighborhood Hits	61
SwissProt Accessions	O43933, Q96S71, Q96S72, Q96S73, Q99994	Gene names	PEX1
Domain Architecture
Description	Peroxisome biogenesis factor 1 (Peroxin-1) (Peroxisome biogenesis disorder protein 1).

SPG7_HUMAN
NC score	0.944940 (rank : 16)	θ value	1.3722e-40 (rank : 23)
Query Neighborhood Hits	85	Target Neighborhood Hits	71	Shared Neighborhood Hits	55
SwissProt Accessions	Q9UQ90, O75756, Q96IB0	Gene names	SPG7, CAR, CMAR, PGN
Domain Architecture
Description	Paraplegin (EC 3.4.24.-) (Spastic paraplegia protein 7).

AFG31_MOUSE
NC score	0.943256 (rank : 17)	θ value	3.72821e-46 (rank : 17)
Query Neighborhood Hits	85	Target Neighborhood Hits	74	Shared Neighborhood Hits	57
SwissProt Accessions	Q920A7	Gene names	Afg3l1
Domain Architecture
Description	AFG3-like protein 1 (EC 3.4.24.-).

ATAD1_HUMAN
NC score	0.940268 (rank : 18)	θ value	3.86705e-35 (rank : 32)
Query Neighborhood Hits	85	Target Neighborhood Hits	75	Shared Neighborhood Hits	60
SwissProt Accessions	Q8NBU5, Q6P4B9, Q8N3G1, Q8WYR9, Q969Y3	Gene names	ATAD1
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 1.

ATAD1_MOUSE
NC score	0.940268 (rank : 19)	θ value	3.86705e-35 (rank : 33)
Query Neighborhood Hits	85	Target Neighborhood Hits	75	Shared Neighborhood Hits	60
SwissProt Accessions	Q9D5T0, Q3U8V2, Q9D7A4	Gene names	Atad1
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 1.

AFG32_HUMAN
NC score	0.940078 (rank : 20)	θ value	1.97686e-47 (rank : 16)
Query Neighborhood Hits	85	Target Neighborhood Hits	72	Shared Neighborhood Hits	57
SwissProt Accessions	Q9Y4W6	Gene names	AFG3L2
Domain Architecture
Description	AFG3-like protein 2 (EC 3.4.24.-) (Paraplegin-like protein).

AFG32_MOUSE
NC score	0.939953 (rank : 21)	θ value	8.87376e-48 (rank : 15)
Query Neighborhood Hits	85	Target Neighborhood Hits	73	Shared Neighborhood Hits	57
SwissProt Accessions	Q8JZQ2	Gene names	Afg3l2
Domain Architecture	No domain graphic available
Description	AFG3-like protein 2 (EC 3.4.24.-).

NVL_MOUSE
NC score	0.938539 (rank : 22)	θ value	1.32601e-43 (rank : 18)
Query Neighborhood Hits	85	Target Neighborhood Hits	110	Shared Neighborhood Hits	60
SwissProt Accessions	Q9DBY8, Q3USC4, Q8BW27, Q8K2B5	Gene names	Nvl
Domain Architecture
Description	Nuclear valosin-containing protein-like (Nuclear VCP-like protein) (NVLp).

NVL_HUMAN
NC score	0.937692 (rank : 23)	θ value	1.12253e-42 (rank : 19)
Query Neighborhood Hits	85	Target Neighborhood Hits	112	Shared Neighborhood Hits	61
SwissProt Accessions	O15381, Q96EM7	Gene names	NVL
Domain Architecture
Description	Nuclear valosin-containing protein-like (Nuclear VCP-like protein) (NVLp).

YMEL1_MOUSE
NC score	0.935608 (rank : 24)	θ value	3.37985e-39 (rank : 27)
Query Neighborhood Hits	85	Target Neighborhood Hits	76	Shared Neighborhood Hits	58
SwissProt Accessions	O88967, Q7TNN5	Gene names	Yme1l1
Domain Architecture
Description	ATP-dependent metalloprotease YME1L1 (EC 3.4.24.-) (YME1-like protein 1) (ATP-dependent metalloprotease FtsH1).

PEX6_HUMAN
NC score	0.933342 (rank : 25)	θ value	2.76489e-41 (rank : 21)
Query Neighborhood Hits	85	Target Neighborhood Hits	99	Shared Neighborhood Hits	61
SwissProt Accessions	Q13608, Q8WYQ2, Q99476	Gene names	PEX6, PXAAA1
Domain Architecture
Description	Peroxisome assembly factor 2 (PAF-2) (Peroxisomal-type ATPase 1) (Peroxin-6) (Peroxisomal biogenesis factor 6).

PEX6_MOUSE
NC score	0.932871 (rank : 26)	θ value	5.21438e-40 (rank : 25)
Query Neighborhood Hits	85	Target Neighborhood Hits	94	Shared Neighborhood Hits	60
SwissProt Accessions	Q99LC9, Q6YNQ9	Gene names	Pex6
Domain Architecture	No domain graphic available
Description	Peroxisome assembly factor 2 (PAF-2) (Peroxisomal-type ATPase 1) (Peroxin-6) (Peroxisomal biogenesis factor 6).

YMEL1_HUMAN
NC score	0.932089 (rank : 27)	θ value	3.37985e-39 (rank : 26)
Query Neighborhood Hits	85	Target Neighborhood Hits	73	Shared Neighborhood Hits	58
SwissProt Accessions	Q96TA2, Q9H1Q0, Q9UMR9	Gene names	YME1L1, FTSH1, YME1L
Domain Architecture
Description	ATP-dependent metalloprotease YME1L1 (EC 3.4.24.-) (YME1-like protein 1) (ATP-dependent metalloprotease FtsH1) (Meg-4) (Presenilin- associated metalloprotease) (PAMP).

KATL1_HUMAN
NC score	0.927387 (rank : 28)	θ value	4.88048e-38 (rank : 29)
Query Neighborhood Hits	85	Target Neighborhood Hits	80	Shared Neighborhood Hits	60
SwissProt Accessions	Q9BW62	Gene names	KATNAL1
Domain Architecture	No domain graphic available
Description	Katanin p60 ATPase-containing subunit A-like 1 (EC 3.6.4.3) (Katanin p60 subunit A-like 1) (p60 katanin-like 1).

KATL1_MOUSE
NC score	0.927380 (rank : 29)	θ value	2.19075e-38 (rank : 28)
Query Neighborhood Hits	85	Target Neighborhood Hits	77	Shared Neighborhood Hits	60
SwissProt Accessions	Q8K0T4	Gene names	Katnal1
Domain Architecture	No domain graphic available
Description	Katanin p60 ATPase-containing subunit A-like 1 (EC 3.6.4.3) (Katanin p60 subunit A-like 1) (p60 katanin-like 1).

KTNA1_HUMAN
NC score	0.924634 (rank : 30)	θ value	2.42216e-37 (rank : 31)
Query Neighborhood Hits	85	Target Neighborhood Hits	117	Shared Neighborhood Hits	60
SwissProt Accessions	O75449, Q5TFA8, Q5TFA9, Q86VN2, Q9NU52	Gene names	KATNA1
Domain Architecture	No domain graphic available
Description	Katanin p60 ATPase-containing subunit A1 (EC 3.6.4.3) (Katanin p60 subunit A1) (p60 katanin).

KTNA1_MOUSE
NC score	0.922854 (rank : 31)	θ value	8.32485e-38 (rank : 30)
Query Neighborhood Hits	85	Target Neighborhood Hits	123	Shared Neighborhood Hits	59
SwissProt Accessions	Q9WV86	Gene names	Katna1
Domain Architecture	No domain graphic available
Description	Katanin p60 ATPase-containing subunit A1 (EC 3.6.4.3) (Katanin p60 subunit A1) (p60 katanin) (Lipotransin).

NSF_MOUSE
NC score	0.919674 (rank : 32)	θ value	2.59387e-31 (rank : 40)
Query Neighborhood Hits	85	Target Neighborhood Hits	73	Shared Neighborhood Hits	59
SwissProt Accessions	P46460	Gene names	Nsf, Skd2
Domain Architecture
Description	Vesicle-fusing ATPase (EC 3.6.4.6) (Vesicular-fusion protein NSF) (N- ethylmaleimide sensitive fusion protein) (NEM-sensitive fusion protein) (SKD2 protein).

SPAST_HUMAN
NC score	0.919169 (rank : 33)	θ value	1.6247e-33 (rank : 34)
Query Neighborhood Hits	85	Target Neighborhood Hits	100	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UBP0, Q9UPR9	Gene names	SPAST, KIAA1083, SPG4
Domain Architecture
Description	Spastin.

NSF_HUMAN
NC score	0.919118 (rank : 34)	θ value	4.42448e-31 (rank : 41)
Query Neighborhood Hits	85	Target Neighborhood Hits	74	Shared Neighborhood Hits	59
SwissProt Accessions	P46459, Q9UKZ2	Gene names	NSF
Domain Architecture
Description	Vesicle-fusing ATPase (EC 3.6.4.6) (Vesicular-fusion protein NSF) (N- ethylmaleimide sensitive fusion protein) (NEM-sensitive fusion protein).

SPAST_MOUSE
NC score	0.917412 (rank : 35)	θ value	4.72714e-33 (rank : 36)
Query Neighborhood Hits	85	Target Neighborhood Hits	138	Shared Neighborhood Hits	57
SwissProt Accessions	Q9QYY8, Q6ZPY6, Q80VE0, Q9CVK0	Gene names	Spast, Kiaa1083, Spg4
Domain Architecture	No domain graphic available
Description	Spastin.

VPS4B_HUMAN
NC score	0.910656 (rank : 36)	θ value	4.72714e-33 (rank : 37)
Query Neighborhood Hits	85	Target Neighborhood Hits	87	Shared Neighborhood Hits	59
SwissProt Accessions	O75351, Q9GZS7	Gene names	VPS4B, SKD1, VPS42
Domain Architecture
Description	Vacuolar protein sorting-associating protein 4B (Protein SKD1).

VPS4B_MOUSE
NC score	0.910401 (rank : 37)	θ value	2.77131e-33 (rank : 35)
Query Neighborhood Hits	85	Target Neighborhood Hits	86	Shared Neighborhood Hits	59
SwissProt Accessions	P46467, Q91W22, Q9R1C9	Gene names	Vps4b, Skd1
Domain Architecture
Description	Vacuolar protein sorting-associating protein 4B (Protein SKD1).

VPS4A_HUMAN
NC score	0.907390 (rank : 38)	θ value	1.98606e-31 (rank : 38)
Query Neighborhood Hits	85	Target Neighborhood Hits	95	Shared Neighborhood Hits	59
SwissProt Accessions	Q9UN37, Q8TF07, Q9UI03, Q9Y582	Gene names	VPS4A, VPS4
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associating protein 4A (SKD2 protein) (hVPS4) (VPS4-1).

VPS4A_MOUSE
NC score	0.907369 (rank : 39)	θ value	1.98606e-31 (rank : 39)
Query Neighborhood Hits	85	Target Neighborhood Hits	94	Shared Neighborhood Hits	59
SwissProt Accessions	Q8VEJ9, Q3TXT2	Gene names	Vps4a
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associating protein 4A.

ATAD2_MOUSE
NC score	0.894334 (rank : 40)	θ value	1.3722e-40 (rank : 22)
Query Neighborhood Hits	85	Target Neighborhood Hits	167	Shared Neighborhood Hits	60
SwissProt Accessions	Q8CDM1	Gene names	Atad2
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 2.

ATAD2_HUMAN
NC score	0.878294 (rank : 41)	θ value	7.27602e-42 (rank : 20)
Query Neighborhood Hits	85	Target Neighborhood Hits	322	Shared Neighborhood Hits	66
SwissProt Accessions	Q6PL18, Q658P2, Q68CQ0, Q6PJV6, Q8N890, Q9UHS5	Gene names	ATAD2
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 2.

FIGN_MOUSE
NC score	0.873859 (rank : 42)	θ value	4.73814e-25 (rank : 42)
Query Neighborhood Hits	85	Target Neighborhood Hits	165	Shared Neighborhood Hits	53
SwissProt Accessions	Q9ERZ6, Q3TPB0, Q3UP57, Q6PCM0	Gene names	Fign
Domain Architecture	No domain graphic available
Description	Fidgetin.

FIGN_HUMAN
NC score	0.868258 (rank : 43)	θ value	8.08199e-25 (rank : 43)
Query Neighborhood Hits	85	Target Neighborhood Hits	176	Shared Neighborhood Hits	53
SwissProt Accessions	Q5HY92, Q9H6M5, Q9NVZ9	Gene names	FIGN
Domain Architecture	No domain graphic available
Description	Fidgetin.

BCS1_HUMAN
NC score	0.699657 (rank : 44)	θ value	3.08544e-08 (rank : 47)
Query Neighborhood Hits	85	Target Neighborhood Hits	61	Shared Neighborhood Hits	54
SwissProt Accessions	Q9Y276, Q7Z2V7	Gene names	BCS1L, BCS1
Domain Architecture
Description	Mitochondrial chaperone BCS1 (BCS1-like protein) (H-BCS1).

BCS1_MOUSE
NC score	0.690644 (rank : 45)	θ value	6.87365e-08 (rank : 48)
Query Neighborhood Hits	85	Target Neighborhood Hits	64	Shared Neighborhood Hits	54
SwissProt Accessions	Q9CZP5	Gene names	Bcs1l
Domain Architecture
Description	Mitochondrial chaperone BCS1 (BCS1-like protein).

TRP13_MOUSE
NC score	0.683967 (rank : 46)	θ value	0.000786445 (rank : 51)
Query Neighborhood Hits	85	Target Neighborhood Hits	81	Shared Neighborhood Hits	57
SwissProt Accessions	Q3UA06, Q3UQG6, Q9CWW8	Gene names	Trip13
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 13 (Thyroid hormone receptor interactor 13) (Trip-13).

TRP13_HUMAN
NC score	0.680171 (rank : 47)	θ value	0.00102713 (rank : 52)
Query Neighborhood Hits	85	Target Neighborhood Hits	81	Shared Neighborhood Hits	57
SwissProt Accessions	Q15645, O15324	Gene names	TRIP13
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 13 (Thyroid hormone receptor interactor 13) (Trip-13) (Human papillomavirus type 16 E1 protein- binding protein) (HPV16 E1 protein-binding protein) (16E1-BP).

ATD3A_HUMAN
NC score	0.642324 (rank : 48)	θ value	3.64472e-09 (rank : 46)
Query Neighborhood Hits	85	Target Neighborhood Hits	248	Shared Neighborhood Hits	63
SwissProt Accessions	Q9NVI7, Q8N275, Q96A50	Gene names	ATAD3A
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 3A.

ATD3B_HUMAN
NC score	0.631098 (rank : 49)	θ value	1.63604e-09 (rank : 45)
Query Neighborhood Hits	85	Target Neighborhood Hits	340	Shared Neighborhood Hits	65
SwissProt Accessions	Q5T9A4, Q6ZRB5, Q9BUK4, Q9ULE7	Gene names	ATAD3B, KIAA1273
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 3B.

ATAD3_MOUSE
NC score	0.624299 (rank : 50)	θ value	9.59137e-10 (rank : 44)
Query Neighborhood Hits	85	Target Neighborhood Hits	326	Shared Neighborhood Hits	66
SwissProt Accessions	Q925I1, Q3UE74, Q69ZM7, Q8C6C6	Gene names	Atad3, Atad3a, Kiaa1273
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 3 (AAA-ATPase TOB3).

CLPX_HUMAN
NC score	0.451823 (rank : 51)	θ value	0.000270298 (rank : 50)
Query Neighborhood Hits	85	Target Neighborhood Hits	72	Shared Neighborhood Hits	51
SwissProt Accessions	O76031, Q9H4D9	Gene names	CLPX
Domain Architecture
Description	ATP-dependent Clp protease ATP-binding subunit ClpX-like, mitochondrial precursor.

CLPX_MOUSE
NC score	0.449977 (rank : 52)	θ value	0.00020696 (rank : 49)
Query Neighborhood Hits	85	Target Neighborhood Hits	73	Shared Neighborhood Hits	51
SwissProt Accessions	Q9JHS4, Q9WVD1	Gene names	Clpx
Domain Architecture
Description	ATP-dependent Clp protease ATP-binding subunit ClpX-like, mitochondrial precursor.

LONM_HUMAN
NC score	0.419752 (rank : 53)	θ value	0.813845 (rank : 61)
Query Neighborhood Hits	85	Target Neighborhood Hits	130	Shared Neighborhood Hits	58
SwissProt Accessions	P36776, P36777, Q9UQ95	Gene names	PRSS15
Domain Architecture
Description	Lon protease homolog, mitochondrial precursor (EC 3.4.21.-) (Lon protease-like protein) (LONP) (LONHs).

RUVB1_HUMAN
NC score	0.308706 (rank : 54)	θ value	0.163984 (rank : 56)
Query Neighborhood Hits	85	Target Neighborhood Hits	78	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Y265, Q9BSX9	Gene names	RUVBL1, NMP238, TIP49, TIP49A
Domain Architecture
Description	RuvB-like 1 (EC 3.6.1.-) (49 kDa TATA box-binding protein-interacting protein) (49 kDa TBP-interacting protein) (TIP49a) (Pontin 52) (Nuclear matrix protein 238) (NMP 238) (54 kDa erythrocyte cytosolic protein) (ECP-54) (TIP60-associated protein 54-alpha) (TAP54-alpha).

RUVB1_MOUSE
NC score	0.308667 (rank : 55)	θ value	0.163984 (rank : 57)
Query Neighborhood Hits	85	Target Neighborhood Hits	78	Shared Neighborhood Hits	56
SwissProt Accessions	P60122, O35753	Gene names	Ruvbl1, Tip49, Tip49a
Domain Architecture
Description	RuvB-like 1 (EC 3.6.1.-) (49 kDa TATA box-binding protein-interacting protein) (49 kDa TBP-interacting protein) (TIP49a) (Pontin 52) (DNA helicase p50).

WRIP1_MOUSE
NC score	0.252233 (rank : 56)	θ value	0.279714 (rank : 59)
Query Neighborhood Hits	85	Target Neighborhood Hits	93	Shared Neighborhood Hits	49
SwissProt Accessions	Q91XU0, Q3TCT7, Q6PDF0, Q8BUW5, Q8BWP6, Q8BY55, Q921W3, Q9EQL3	Gene names	Wrnip1, Whip
Domain Architecture	No domain graphic available
Description	ATPase WRNIP1 (Werner helicase-interacting protein 1).

WRIP1_HUMAN
NC score	0.249560 (rank : 57)	θ value	0.125558 (rank : 55)
Query Neighborhood Hits	85	Target Neighborhood Hits	100	Shared Neighborhood Hits	50
SwissProt Accessions	Q96S55, Q53EP6, Q59ET8, Q5W0E2, Q5W0E4, Q8WV26, Q9H681, Q9NRJ6	Gene names	WRNIP1, WHIP
Domain Architecture	No domain graphic available
Description	ATPase WRNIP1 (Werner helicase-interacting protein 1).

RFC4_HUMAN
NC score	0.111798 (rank : 58)	θ value	5.27518 (rank : 75)
Query Neighborhood Hits	85	Target Neighborhood Hits	64	Shared Neighborhood Hits	40
SwissProt Accessions	P35249, Q6FHX7	Gene names	RFC4
Domain Architecture
Description	Replication factor C subunit 4 (Replication factor C 37 kDa subunit) (RF-C 37 kDa subunit) (RFC37) (Activator 1 37 kDa subunit) (A1 37 kDa subunit).

RFC1_MOUSE
NC score	0.111189 (rank : 59)	θ value	θ > 10 (rank : 89)
Query Neighborhood Hits	85	Target Neighborhood Hits	290	Shared Neighborhood Hits	46
SwissProt Accessions	P35601	Gene names	Rfc1, Ibf-1, Recc1
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (A1-P145) (Differentiation- specific element-binding protein) (ISRE-binding protein).

RUVB2_HUMAN
NC score	0.110868 (rank : 60)	θ value	θ > 10 (rank : 91)
Query Neighborhood Hits	85	Target Neighborhood Hits	43	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Y230, Q6PK27, Q9Y361	Gene names	RUVBL2, TIP48, TIP49B
Domain Architecture
Description	RuvB-like 2 (EC 3.6.1.-) (48 kDa TATA box-binding protein-interacting protein) (48 kDa TBP-interacting protein) (TIP49b) (Repressing pontin 52) (Reptin 52) (51 kDa erythrocyte cytosolic protein) (ECP-51) (TIP60-associated protein 54-beta) (TAP54-beta).

RUVB2_MOUSE
NC score	0.108271 (rank : 61)	θ value	θ > 10 (rank : 92)
Query Neighborhood Hits	85	Target Neighborhood Hits	42	Shared Neighborhood Hits	36
SwissProt Accessions	Q9WTM5	Gene names	Ruvbl2
Domain Architecture
Description	RuvB-like 2 (EC 3.6.1.-) (p47 protein).

RFC4_MOUSE
NC score	0.100818 (rank : 62)	θ value	5.27518 (rank : 76)
Query Neighborhood Hits	85	Target Neighborhood Hits	65	Shared Neighborhood Hits	40
SwissProt Accessions	Q99J62	Gene names	Rfc4
Domain Architecture	No domain graphic available
Description	Replication factor C subunit 4.

THNSL_MOUSE
NC score	0.099048 (rank : 63)	θ value	θ > 10 (rank : 94)
Query Neighborhood Hits	85	Target Neighborhood Hits	47	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BH55	Gene names	Thnsl1
Domain Architecture	No domain graphic available
Description	Threonine synthase-like 1.

RFC1_HUMAN
NC score	0.098855 (rank : 64)	θ value	θ > 10 (rank : 88)
Query Neighborhood Hits	85	Target Neighborhood Hits	352	Shared Neighborhood Hits	45
SwissProt Accessions	P35251, Q5XKF5, Q6PKU0, Q86V41, Q86V46	Gene names	RFC1, RFC140
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (DNA-binding protein PO-GA).

THNSL_HUMAN
NC score	0.095754 (rank : 65)	θ value	θ > 10 (rank : 93)
Query Neighborhood Hits	85	Target Neighborhood Hits	47	Shared Neighborhood Hits	31
SwissProt Accessions	Q8IYQ7, Q5VV21	Gene names	THNSL1
Domain Architecture	No domain graphic available
Description	Threonine synthase-like 1.

RFC5_MOUSE
NC score	0.091967 (rank : 66)	θ value	0.0431538 (rank : 53)
Query Neighborhood Hits	85	Target Neighborhood Hits	58	Shared Neighborhood Hits	32
SwissProt Accessions	Q9D0F6	Gene names	Rfc5
Domain Architecture
Description	Replication factor C subunit 5 (Replication factor C 36 kDa subunit) (RF-C 36 kDa subunit) (RFC36) (Activator 1 36 kDa subunit) (A1 36 kDa subunit).

KAD6_HUMAN
NC score	0.090932 (rank : 67)	θ value	θ > 10 (rank : 86)
Query Neighborhood Hits	85	Target Neighborhood Hits	46	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y3D8	Gene names	AK6
Domain Architecture
Description	Adenylate kinase isoenzyme 6 (EC 2.7.4.3) (ATP-AMP transphosphorylase 6).

RFC5_HUMAN
NC score	0.090599 (rank : 68)	θ value	0.0563607 (rank : 54)
Query Neighborhood Hits	85	Target Neighborhood Hits	60	Shared Neighborhood Hits	30
SwissProt Accessions	P40937	Gene names	RFC5
Domain Architecture
Description	Replication factor C subunit 5 (Replication factor C 36 kDa subunit) (RF-C 36 kDa subunit) (RFC36) (Activator 1 36 kDa subunit) (A1 36 kDa subunit).

KAD6_MOUSE
NC score	0.070425 (rank : 69)	θ value	θ > 10 (rank : 87)
Query Neighborhood Hits	85	Target Neighborhood Hits	34	Shared Neighborhood Hits	19
SwissProt Accessions	Q8VCP8	Gene names	Ak6
Domain Architecture	No domain graphic available
Description	Adenylate kinase isoenzyme 6 (EC 2.7.4.3) (ATP-AMP transphosphorylase 6).

RFC2_HUMAN
NC score	0.050582 (rank : 70)	θ value	θ > 10 (rank : 90)
Query Neighborhood Hits	85	Target Neighborhood Hits	46	Shared Neighborhood Hits	20
SwissProt Accessions	P35250, P32846, Q9BU93	Gene names	RFC2
Domain Architecture
Description	Replication factor C subunit 2 (Replication factor C 40 kDa subunit) (RF-C 40 kDa subunit) (RFC40) (Activator 1 40 kDa subunit) (A1 40 kDa subunit).

MDN1_HUMAN
NC score	0.036232 (rank : 71)	θ value	8.99809 (rank : 82)
Query Neighborhood Hits	85	Target Neighborhood Hits	662	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

RENT1_MOUSE
NC score	0.025028 (rank : 72)	θ value	6.88961 (rank : 81)
Query Neighborhood Hits	85	Target Neighborhood Hits	54	Shared Neighborhood Hits	11
SwissProt Accessions	Q9EPU0, Q99PR4	Gene names	Upf1, Rent1
Domain Architecture
Description	Regulator of nonsense transcripts 1 (EC 3.6.1.-) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up- frameshift suppressor 1 homolog) (mUpf1).

RENT1_HUMAN
NC score	0.023447 (rank : 73)	θ value	8.99809 (rank : 84)
Query Neighborhood Hits	85	Target Neighborhood Hits	51	Shared Neighborhood Hits	11
SwissProt Accessions	Q92900, O00239, O43343, Q86Z25, Q92842	Gene names	UPF1, KIAA0221, RENT1
Domain Architecture
Description	Regulator of nonsense transcripts 1 (EC 3.6.1.-) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up- frameshift suppressor 1 homolog) (hUpf1).

NAB1_HUMAN
NC score	0.021343 (rank : 74)	θ value	2.36792 (rank : 65)
Query Neighborhood Hits	85	Target Neighborhood Hits	33	Shared Neighborhood Hits	7
SwissProt Accessions	Q13506, O75383, O75384, Q6GTU1, Q9UEV1	Gene names	NAB1
Domain Architecture
Description	NGFI-A-binding protein 1 (EGR-1-binding protein 1) (Transcriptional regulatory protein p54).

NAB1_MOUSE
NC score	0.018726 (rank : 75)	θ value	3.0926 (rank : 68)
Query Neighborhood Hits	85	Target Neighborhood Hits	19	Shared Neighborhood Hits	4
SwissProt Accessions	Q61122	Gene names	Nab1
Domain Architecture
Description	NGFI-A-binding protein 1 (EGR-1-binding protein 1).

SMC2_HUMAN
NC score	0.014766 (rank : 76)	θ value	0.279714 (rank : 58)
Query Neighborhood Hits	85	Target Neighborhood Hits	1405	Shared Neighborhood Hits	24
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

SMC2_MOUSE
NC score	0.013133 (rank : 77)	θ value	0.813845 (rank : 62)
Query Neighborhood Hits	85	Target Neighborhood Hits	1131	Shared Neighborhood Hits	19
SwissProt Accessions	Q8CG48, Q61076, Q9CS17, Q9CSD8	Gene names	Smc2l1, Cape, Fin16, Smc2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (XCAP-E homolog) (FGF-inducible protein 16).

CE290_HUMAN
NC score	0.012913 (rank : 78)	θ value	1.38821 (rank : 63)
Query Neighborhood Hits	85	Target Neighborhood Hits	1553	Shared Neighborhood Hits	25
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

SPAG5_MOUSE
NC score	0.012032 (rank : 79)	θ value	5.27518 (rank : 77)
Query Neighborhood Hits	85	Target Neighborhood Hits	612	Shared Neighborhood Hits	20
SwissProt Accessions	Q7TME2, Q8CH61	Gene names	Spag5
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 5 (Mastrin) (Mitotic spindle-associated protein p126) (MAP126).

TAXB1_HUMAN
NC score	0.010259 (rank : 80)	θ value	0.62314 (rank : 60)
Query Neighborhood Hits	85	Target Neighborhood Hits	829	Shared Neighborhood Hits	19
SwissProt Accessions	Q86VP1, O60398, O95770, Q13311, Q9BQG5, Q9UI88	Gene names	TAX1BP1, T6BP
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 1 (TRAF6-binding protein).

SMC4_MOUSE
NC score	0.009705 (rank : 81)	θ value	3.0926 (rank : 70)
Query Neighborhood Hits	85	Target Neighborhood Hits	830	Shared Neighborhood Hits	18
SwissProt Accessions	Q8CG47, Q8BTS7, Q8BTY9, Q99K21	Gene names	Smc4l1, Capc, Smc4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (XCAP-C homolog).

RBP22_HUMAN
NC score	0.009059 (rank : 82)	θ value	3.0926 (rank : 69)
Query Neighborhood Hits	85	Target Neighborhood Hits	165	Shared Neighborhood Hits	8
SwissProt Accessions	Q53T03, Q53QN2, Q59GM7	Gene names	RANBP2L2
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 2 (RanBP2L2).

CCD13_HUMAN
NC score	0.006655 (rank : 83)	θ value	2.36792 (rank : 64)
Query Neighborhood Hits	85	Target Neighborhood Hits	721	Shared Neighborhood Hits	18
SwissProt Accessions	Q8IYE1	Gene names	CCDC13
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 13.

DOCK8_HUMAN
NC score	0.006415 (rank : 84)	θ value	5.27518 (rank : 72)
Query Neighborhood Hits	85	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NF50, Q3MV16, Q5JPJ1, Q8TEP1, Q8WUY2, Q9BYJ5, Q9H1Q2, Q9H1Q3, Q9H308, Q9H7P2	Gene names	DOCK8
Domain Architecture	No domain graphic available
Description	Dedicator of cytokinesis protein 8.

TRIPB_HUMAN
NC score	0.006110 (rank : 85)	θ value	3.0926 (rank : 71)
Query Neighborhood Hits	85	Target Neighborhood Hits	1587	Shared Neighborhood Hits	25
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

OPTN_MOUSE
NC score	0.005750 (rank : 86)	θ value	5.27518 (rank : 73)
Query Neighborhood Hits	85	Target Neighborhood Hits	1120	Shared Neighborhood Hits	25
SwissProt Accessions	Q8K3K8	Gene names	Optn
Domain Architecture	No domain graphic available
Description	Optineurin.

MORC4_MOUSE
NC score	0.005712 (rank : 87)	θ value	8.99809 (rank : 83)
Query Neighborhood Hits	85	Target Neighborhood Hits	235	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BMD7, Q4KMM6, Q8BX95, Q9CS96	Gene names	Morc4, Zcwcc2
Domain Architecture	No domain graphic available
Description	MORC family CW-type zinc finger protein 4 (Zinc finger CW-type coiled- coil domain protein 2).

CENPF_HUMAN
NC score	0.004827 (rank : 88)	θ value	3.0926 (rank : 66)
Query Neighborhood Hits	85	Target Neighborhood Hits	1932	Shared Neighborhood Hits	23
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

NAF1_MOUSE
NC score	0.003618 (rank : 89)	θ value	6.88961 (rank : 80)
Query Neighborhood Hits	85	Target Neighborhood Hits	852	Shared Neighborhood Hits	18
SwissProt Accessions	Q9WUU8, Q922A9, Q922F7, Q9EPP8, Q9R0X3	Gene names	Tnip1, Abin, Naf1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (A20- binding inhibitor of NF-kappa-B activation) (ABIN) (Virion-associated nuclear shuttling protein) (VAN) (mVAN).

PEPL_HUMAN
NC score	0.003053 (rank : 90)	θ value	5.27518 (rank : 74)
Query Neighborhood Hits	85	Target Neighborhood Hits	1141	Shared Neighborhood Hits	18
SwissProt Accessions	O60437, O60314, O60454	Gene names	PPL, KIAA0568
Domain Architecture
Description	Periplakin (195 kDa cornified envelope precursor protein) (190 kDa paraneoplastic pemphigus antigen).

EEA1_HUMAN
NC score	0.002291 (rank : 91)	θ value	6.88961 (rank : 78)
Query Neighborhood Hits	85	Target Neighborhood Hits	1796	Shared Neighborhood Hits	21
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

MYH14_HUMAN
NC score	0.001982 (rank : 92)	θ value	3.0926 (rank : 67)
Query Neighborhood Hits	85	Target Neighborhood Hits	995	Shared Neighborhood Hits	18
SwissProt Accessions	Q7Z406, Q5CZ75, Q6XYE4, Q76B62, Q8WV23, Q96I22, Q9BT27, Q9BW35, Q9H882	Gene names	MYH14, KIAA2034
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

KINH_HUMAN
NC score	0.001843 (rank : 93)	θ value	6.88961 (rank : 79)
Query Neighborhood Hits	85	Target Neighborhood Hits	1231	Shared Neighborhood Hits	22
SwissProt Accessions	P33176, Q5VZ85	Gene names	KIF5B, KNS, KNS1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

UACA_HUMAN
NC score	0.000328 (rank : 94)	θ value	8.99809 (rank : 85)
Query Neighborhood Hits	85	Target Neighborhood Hits	1622	Shared Neighborhood Hits	24
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.