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Network neighborhood for query Sequence : RFC4_MOUSE

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RFC4_MOUSE
SwissProt Accessions	Q99J62	Gene names	Rfc4
Domain Architecture	No domain graphic available
Description	Replication factor C subunit 4.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

RFC4_HUMAN
θ value	0 (rank : 1)	NC score	0.997743 (rank : 2)
Query Neighborhood Hits	65	Target Neighborhood Hits	64	Shared Neighborhood Hits	59
SwissProt Accessions	P35249, Q6FHX7	Gene names	RFC4
Domain Architecture
Description	Replication factor C subunit 4 (Replication factor C 37 kDa subunit) (RF-C 37 kDa subunit) (RFC37) (Activator 1 37 kDa subunit) (A1 37 kDa subunit).

RFC4_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	65	Target Neighborhood Hits	65	Shared Neighborhood Hits	65
SwissProt Accessions	Q99J62	Gene names	Rfc4
Domain Architecture	No domain graphic available
Description	Replication factor C subunit 4.

RFC5_HUMAN
θ value	1.15626e-55 (rank : 3)	NC score	0.925909 (rank : 4)
Query Neighborhood Hits	65	Target Neighborhood Hits	60	Shared Neighborhood Hits	38
SwissProt Accessions	P40937	Gene names	RFC5
Domain Architecture
Description	Replication factor C subunit 5 (Replication factor C 36 kDa subunit) (RF-C 36 kDa subunit) (RFC36) (Activator 1 36 kDa subunit) (A1 36 kDa subunit).

RFC5_MOUSE
θ value	3.36421e-55 (rank : 4)	NC score	0.927803 (rank : 3)
Query Neighborhood Hits	65	Target Neighborhood Hits	58	Shared Neighborhood Hits	40
SwissProt Accessions	Q9D0F6	Gene names	Rfc5
Domain Architecture
Description	Replication factor C subunit 5 (Replication factor C 36 kDa subunit) (RF-C 36 kDa subunit) (RFC36) (Activator 1 36 kDa subunit) (A1 36 kDa subunit).

RFC2_HUMAN
θ value	3.04986e-48 (rank : 5)	NC score	0.909806 (rank : 5)
Query Neighborhood Hits	65	Target Neighborhood Hits	46	Shared Neighborhood Hits	27
SwissProt Accessions	P35250, P32846, Q9BU93	Gene names	RFC2
Domain Architecture
Description	Replication factor C subunit 2 (Replication factor C 40 kDa subunit) (RF-C 40 kDa subunit) (RFC40) (Activator 1 40 kDa subunit) (A1 40 kDa subunit).

RFC2_MOUSE
θ value	3.98324e-48 (rank : 6)	NC score	0.909169 (rank : 6)
Query Neighborhood Hits	65	Target Neighborhood Hits	46	Shared Neighborhood Hits	27
SwissProt Accessions	Q9WUK4	Gene names	Rfc2
Domain Architecture
Description	Replication factor C subunit 2 (Replication factor C 40 kDa subunit) (RF-C 40 kDa subunit) (RFC40) (Activator 1 40 kDa subunit) (A1 40 kDa subunit).

RFC3_HUMAN
θ value	1.37858e-24 (rank : 7)	NC score	0.788078 (rank : 8)
Query Neighborhood Hits	65	Target Neighborhood Hits	16	Shared Neighborhood Hits	14
SwissProt Accessions	P40938, O15252	Gene names	RFC3
Domain Architecture
Description	Replication factor C subunit 3 (Replication factor C 38 kDa subunit) (RFC38) (Activator 1 38 kDa subunit) (A1 38 kDa subunit) (RF-C 38 kDa subunit).

RFC3_MOUSE
θ value	1.80048e-24 (rank : 8)	NC score	0.790293 (rank : 7)
Query Neighborhood Hits	65	Target Neighborhood Hits	18	Shared Neighborhood Hits	14
SwissProt Accessions	Q8R323	Gene names	Rfc3
Domain Architecture
Description	Replication factor C subunit 3 (Replication factor C 38 kDa subunit) (RFC38) (Activator 1 38 kDa subunit) (A1 38 kDa subunit) (RF-C 38 kDa subunit).

RFC1_HUMAN
θ value	8.40245e-06 (rank : 9)	NC score	0.355331 (rank : 10)
Query Neighborhood Hits	65	Target Neighborhood Hits	352	Shared Neighborhood Hits	36
SwissProt Accessions	P35251, Q5XKF5, Q6PKU0, Q86V41, Q86V46	Gene names	RFC1, RFC140
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (DNA-binding protein PO-GA).

RFC1_MOUSE
θ value	0.000121331 (rank : 10)	NC score	0.363056 (rank : 9)
Query Neighborhood Hits	65	Target Neighborhood Hits	290	Shared Neighborhood Hits	37
SwissProt Accessions	P35601	Gene names	Rfc1, Ibf-1, Recc1
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (A1-P145) (Differentiation- specific element-binding protein) (ISRE-binding protein).

RAD17_MOUSE
θ value	0.00390308 (rank : 11)	NC score	0.332373 (rank : 11)
Query Neighborhood Hits	65	Target Neighborhood Hits	63	Shared Neighborhood Hits	27
SwissProt Accessions	Q6NXW6, O88934, O89024	Gene names	Rad17
Domain Architecture	No domain graphic available
Description	Cell cycle checkpoint protein RAD17.

WRIP1_MOUSE
θ value	0.00390308 (rank : 12)	NC score	0.323715 (rank : 12)
Query Neighborhood Hits	65	Target Neighborhood Hits	93	Shared Neighborhood Hits	37
SwissProt Accessions	Q91XU0, Q3TCT7, Q6PDF0, Q8BUW5, Q8BWP6, Q8BY55, Q921W3, Q9EQL3	Gene names	Wrnip1, Whip
Domain Architecture	No domain graphic available
Description	ATPase WRNIP1 (Werner helicase-interacting protein 1).

RAD17_HUMAN
θ value	0.0113563 (rank : 13)	NC score	0.300151 (rank : 13)
Query Neighborhood Hits	65	Target Neighborhood Hits	44	Shared Neighborhood Hits	21
SwissProt Accessions	O75943, O75714, Q7Z3S4, Q9UNK7, Q9UNR7, Q9UNR8, Q9UPF5	Gene names	RAD17, R24L
Domain Architecture	No domain graphic available
Description	Cell cycle checkpoint protein RAD17 (hRad17) (RF-C/activator 1 homolog).

WRIP1_HUMAN
θ value	0.0252991 (rank : 14)	NC score	0.289182 (rank : 14)
Query Neighborhood Hits	65	Target Neighborhood Hits	100	Shared Neighborhood Hits	37
SwissProt Accessions	Q96S55, Q53EP6, Q59ET8, Q5W0E2, Q5W0E4, Q8WV26, Q9H681, Q9NRJ6	Gene names	WRNIP1, WHIP
Domain Architecture	No domain graphic available
Description	ATPase WRNIP1 (Werner helicase-interacting protein 1).

PRS10_HUMAN
θ value	0.0961366 (rank : 15)	NC score	0.120975 (rank : 18)
Query Neighborhood Hits	65	Target Neighborhood Hits	95	Shared Neighborhood Hits	44
SwissProt Accessions	P62333, P49719, Q6IBU3, Q92524	Gene names	PSMC6, SUG2
Domain Architecture
Description	26S protease regulatory subunit S10B (Proteasome subunit p42) (Proteasome 26S subunit ATPase 6).

PRS10_MOUSE
θ value	0.0961366 (rank : 16)	NC score	0.120975 (rank : 19)
Query Neighborhood Hits	65	Target Neighborhood Hits	95	Shared Neighborhood Hits	44
SwissProt Accessions	P62334, P49719, Q3TKK1, Q810A6, Q92524, Q9CXH9	Gene names	Psmc6, Sug2
Domain Architecture
Description	26S protease regulatory subunit S10B (Proteasome subunit p42) (Proteasome 26S subunit ATPase 6).

M10L1_MOUSE
θ value	0.125558 (rank : 17)	NC score	0.084022 (rank : 57)
Query Neighborhood Hits	65	Target Neighborhood Hits	59	Shared Neighborhood Hits	12
SwissProt Accessions	Q99MV5, Q7TPA9, Q8C3W0, Q924C2	Gene names	Mov10l1, Champ
Domain Architecture
Description	Putative helicase Mov10l1 (EC 3.6.1.-) (Moloney leukemia virus 10-like protein 1) (MOV10-like 1) (Cardiac helicase activated by MEF2 protein) (Cardiac-specific RNA helicase).

NVL_MOUSE
θ value	0.21417 (rank : 18)	NC score	0.123960 (rank : 16)
Query Neighborhood Hits	65	Target Neighborhood Hits	110	Shared Neighborhood Hits	42
SwissProt Accessions	Q9DBY8, Q3USC4, Q8BW27, Q8K2B5	Gene names	Nvl
Domain Architecture
Description	Nuclear valosin-containing protein-like (Nuclear VCP-like protein) (NVLp).

CDC6_HUMAN
θ value	0.279714 (rank : 19)	NC score	0.120908 (rank : 20)
Query Neighborhood Hits	65	Target Neighborhood Hits	30	Shared Neighborhood Hits	12
SwissProt Accessions	Q99741, Q8TB30	Gene names	CDC6, CDC18L
Domain Architecture	No domain graphic available
Description	Cell division control protein 6 homolog (CDC6-related protein) (p62(cdc6)) (HsCDC6) (HsCDC18).

LONM_HUMAN
θ value	0.365318 (rank : 20)	NC score	0.128525 (rank : 15)
Query Neighborhood Hits	65	Target Neighborhood Hits	130	Shared Neighborhood Hits	36
SwissProt Accessions	P36776, P36777, Q9UQ95	Gene names	PRSS15
Domain Architecture
Description	Lon protease homolog, mitochondrial precursor (EC 3.4.21.-) (Lon protease-like protein) (LONP) (LONHs).

NVL_HUMAN
θ value	0.365318 (rank : 21)	NC score	0.123347 (rank : 17)
Query Neighborhood Hits	65	Target Neighborhood Hits	112	Shared Neighborhood Hits	44
SwissProt Accessions	O15381, Q96EM7	Gene names	NVL
Domain Architecture
Description	Nuclear valosin-containing protein-like (Nuclear VCP-like protein) (NVLp).

TERA_HUMAN
θ value	0.62314 (rank : 22)	NC score	0.114440 (rank : 23)
Query Neighborhood Hits	65	Target Neighborhood Hits	76	Shared Neighborhood Hits	41
SwissProt Accessions	P55072, Q969G7	Gene names	VCP
Domain Architecture
Description	Transitional endoplasmic reticulum ATPase (TER ATPase) (15S Mg(2+)- ATPase p97 subunit) (Valosin-containing protein) (VCP).

TERA_MOUSE
θ value	0.62314 (rank : 23)	NC score	0.114459 (rank : 22)
Query Neighborhood Hits	65	Target Neighborhood Hits	76	Shared Neighborhood Hits	41
SwissProt Accessions	Q01853	Gene names	Vcp
Domain Architecture
Description	Transitional endoplasmic reticulum ATPase (TER ATPase) (15S Mg(2+)- ATPase p97 subunit) (Valosin-containing protein) (VCP).

VPS4B_HUMAN
θ value	0.62314 (rank : 24)	NC score	0.104273 (rank : 30)
Query Neighborhood Hits	65	Target Neighborhood Hits	87	Shared Neighborhood Hits	38
SwissProt Accessions	O75351, Q9GZS7	Gene names	VPS4B, SKD1, VPS42
Domain Architecture
Description	Vacuolar protein sorting-associating protein 4B (Protein SKD1).

VPS4B_MOUSE
θ value	0.62314 (rank : 25)	NC score	0.103501 (rank : 31)
Query Neighborhood Hits	65	Target Neighborhood Hits	86	Shared Neighborhood Hits	37
SwissProt Accessions	P46467, Q91W22, Q9R1C9	Gene names	Vps4b, Skd1
Domain Architecture
Description	Vacuolar protein sorting-associating protein 4B (Protein SKD1).

PEX6_HUMAN
θ value	0.813845 (rank : 26)	NC score	0.114096 (rank : 24)
Query Neighborhood Hits	65	Target Neighborhood Hits	99	Shared Neighborhood Hits	44
SwissProt Accessions	Q13608, Q8WYQ2, Q99476	Gene names	PEX6, PXAAA1
Domain Architecture
Description	Peroxisome assembly factor 2 (PAF-2) (Peroxisomal-type ATPase 1) (Peroxin-6) (Peroxisomal biogenesis factor 6).

PR285_HUMAN
θ value	0.813845 (rank : 27)	NC score	0.075108 (rank : 69)
Query Neighborhood Hits	65	Target Neighborhood Hits	63	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BYK8, Q3C2G2, Q4VXQ1, Q8TEF3, Q96ND3, Q9C094	Gene names	PRIC285, KIAA1769
Domain Architecture
Description	Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein (EC 3.6.1.-) (ATP-dependent helicase PRIC285) (PPAR-alpha- interacting complex protein 285) (PPAR-gamma DBD-interacting protein 1) (PDIP1).

PEX6_MOUSE
θ value	1.06291 (rank : 28)	NC score	0.113732 (rank : 26)
Query Neighborhood Hits	65	Target Neighborhood Hits	94	Shared Neighborhood Hits	42
SwissProt Accessions	Q99LC9, Q6YNQ9	Gene names	Pex6
Domain Architecture	No domain graphic available
Description	Peroxisome assembly factor 2 (PAF-2) (Peroxisomal-type ATPase 1) (Peroxin-6) (Peroxisomal biogenesis factor 6).

KIF22_HUMAN
θ value	1.38821 (rank : 29)	NC score	0.017321 (rank : 80)
Query Neighborhood Hits	65	Target Neighborhood Hits	110	Shared Neighborhood Hits	4
SwissProt Accessions	Q14807, O94814, Q9BT46	Gene names	KIF22, KID, KNSL4
Domain Architecture
Description	Kinesin-like protein KIF22 (Kinesin-like DNA-binding protein) (Kinesin-like protein 4).

ATAD2_HUMAN
θ value	1.81305 (rank : 30)	NC score	0.089793 (rank : 49)
Query Neighborhood Hits	65	Target Neighborhood Hits	322	Shared Neighborhood Hits	37
SwissProt Accessions	Q6PL18, Q658P2, Q68CQ0, Q6PJV6, Q8N890, Q9UHS5	Gene names	ATAD2
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 2.

ATAD2_MOUSE
θ value	1.81305 (rank : 31)	NC score	0.091670 (rank : 46)
Query Neighborhood Hits	65	Target Neighborhood Hits	167	Shared Neighborhood Hits	37
SwissProt Accessions	Q8CDM1	Gene names	Atad2
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 2.

TRP13_HUMAN
θ value	1.81305 (rank : 32)	NC score	0.113896 (rank : 25)
Query Neighborhood Hits	65	Target Neighborhood Hits	81	Shared Neighborhood Hits	37
SwissProt Accessions	Q15645, O15324	Gene names	TRIP13
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 13 (Thyroid hormone receptor interactor 13) (Trip-13) (Human papillomavirus type 16 E1 protein- binding protein) (HPV16 E1 protein-binding protein) (16E1-BP).

TRP13_MOUSE
θ value	1.81305 (rank : 33)	NC score	0.114947 (rank : 21)
Query Neighborhood Hits	65	Target Neighborhood Hits	81	Shared Neighborhood Hits	37
SwissProt Accessions	Q3UA06, Q3UQG6, Q9CWW8	Gene names	Trip13
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 13 (Thyroid hormone receptor interactor 13) (Trip-13).

YMEL1_HUMAN
θ value	1.81305 (rank : 34)	NC score	0.106573 (rank : 28)
Query Neighborhood Hits	65	Target Neighborhood Hits	73	Shared Neighborhood Hits	37
SwissProt Accessions	Q96TA2, Q9H1Q0, Q9UMR9	Gene names	YME1L1, FTSH1, YME1L
Domain Architecture
Description	ATP-dependent metalloprotease YME1L1 (EC 3.4.24.-) (YME1-like protein 1) (ATP-dependent metalloprotease FtsH1) (Meg-4) (Presenilin- associated metalloprotease) (PAMP).

KATL1_MOUSE
θ value	2.36792 (rank : 35)	NC score	0.097640 (rank : 39)
Query Neighborhood Hits	65	Target Neighborhood Hits	77	Shared Neighborhood Hits	38
SwissProt Accessions	Q8K0T4	Gene names	Katnal1
Domain Architecture	No domain graphic available
Description	Katanin p60 ATPase-containing subunit A-like 1 (EC 3.6.4.3) (Katanin p60 subunit A-like 1) (p60 katanin-like 1).

KTNA1_MOUSE
θ value	2.36792 (rank : 36)	NC score	0.097165 (rank : 41)
Query Neighborhood Hits	65	Target Neighborhood Hits	123	Shared Neighborhood Hits	38
SwissProt Accessions	Q9WV86	Gene names	Katna1
Domain Architecture	No domain graphic available
Description	Katanin p60 ATPase-containing subunit A1 (EC 3.6.4.3) (Katanin p60 subunit A1) (p60 katanin) (Lipotransin).

M10L1_HUMAN
θ value	2.36792 (rank : 37)	NC score	0.084057 (rank : 56)
Query Neighborhood Hits	65	Target Neighborhood Hits	36	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BXT6, Q5TGD5, Q8NBD4, Q9NXW3, Q9UFB3, Q9UGX9	Gene names	MOV10L1
Domain Architecture
Description	Putative helicase Mov10l1 (EC 3.6.1.-) (Moloney leukemia virus 10-like protein 1) (MOV10-like 1).

RUVB1_HUMAN
θ value	2.36792 (rank : 38)	NC score	0.101697 (rank : 32)
Query Neighborhood Hits	65	Target Neighborhood Hits	78	Shared Neighborhood Hits	40
SwissProt Accessions	Q9Y265, Q9BSX9	Gene names	RUVBL1, NMP238, TIP49, TIP49A
Domain Architecture
Description	RuvB-like 1 (EC 3.6.1.-) (49 kDa TATA box-binding protein-interacting protein) (49 kDa TBP-interacting protein) (TIP49a) (Pontin 52) (Nuclear matrix protein 238) (NMP 238) (54 kDa erythrocyte cytosolic protein) (ECP-54) (TIP60-associated protein 54-alpha) (TAP54-alpha).

RUVB1_MOUSE
θ value	2.36792 (rank : 39)	NC score	0.101684 (rank : 33)
Query Neighborhood Hits	65	Target Neighborhood Hits	78	Shared Neighborhood Hits	40
SwissProt Accessions	P60122, O35753	Gene names	Ruvbl1, Tip49, Tip49a
Domain Architecture
Description	RuvB-like 1 (EC 3.6.1.-) (49 kDa TATA box-binding protein-interacting protein) (49 kDa TBP-interacting protein) (TIP49a) (Pontin 52) (DNA helicase p50).

YMEL1_MOUSE
θ value	2.36792 (rank : 40)	NC score	0.105288 (rank : 29)
Query Neighborhood Hits	65	Target Neighborhood Hits	76	Shared Neighborhood Hits	37
SwissProt Accessions	O88967, Q7TNN5	Gene names	Yme1l1
Domain Architecture
Description	ATP-dependent metalloprotease YME1L1 (EC 3.4.24.-) (YME1-like protein 1) (ATP-dependent metalloprotease FtsH1).

BCS1_HUMAN
θ value	3.0926 (rank : 41)	NC score	0.110501 (rank : 27)
Query Neighborhood Hits	65	Target Neighborhood Hits	61	Shared Neighborhood Hits	36
SwissProt Accessions	Q9Y276, Q7Z2V7	Gene names	BCS1L, BCS1
Domain Architecture
Description	Mitochondrial chaperone BCS1 (BCS1-like protein) (H-BCS1).

BCS1_MOUSE
θ value	3.0926 (rank : 42)	NC score	0.101360 (rank : 34)
Query Neighborhood Hits	65	Target Neighborhood Hits	64	Shared Neighborhood Hits	36
SwissProt Accessions	Q9CZP5	Gene names	Bcs1l
Domain Architecture
Description	Mitochondrial chaperone BCS1 (BCS1-like protein).

CF060_HUMAN
θ value	3.0926 (rank : 43)	NC score	0.003823 (rank : 86)
Query Neighborhood Hits	65	Target Neighborhood Hits	1270	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NB25, Q96GY8, Q9H851	Gene names	C6orf60
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf60.

VPS4A_HUMAN
θ value	3.0926 (rank : 44)	NC score	0.100884 (rank : 35)
Query Neighborhood Hits	65	Target Neighborhood Hits	95	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UN37, Q8TF07, Q9UI03, Q9Y582	Gene names	VPS4A, VPS4
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associating protein 4A (SKD2 protein) (hVPS4) (VPS4-1).

VPS4A_MOUSE
θ value	3.0926 (rank : 45)	NC score	0.100879 (rank : 36)
Query Neighborhood Hits	65	Target Neighborhood Hits	94	Shared Neighborhood Hits	40
SwissProt Accessions	Q8VEJ9, Q3TXT2	Gene names	Vps4a
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associating protein 4A.

HELZ_HUMAN
θ value	4.03905 (rank : 46)	NC score	0.066064 (rank : 72)
Query Neighborhood Hits	65	Target Neighborhood Hits	198	Shared Neighborhood Hits	13
SwissProt Accessions	P42694	Gene names	HELZ, KIAA0054
Domain Architecture	No domain graphic available
Description	Probable helicase with zinc-finger domain (EC 3.6.1.-).

RENT1_HUMAN
θ value	4.03905 (rank : 47)	NC score	0.049050 (rank : 79)
Query Neighborhood Hits	65	Target Neighborhood Hits	51	Shared Neighborhood Hits	13
SwissProt Accessions	Q92900, O00239, O43343, Q86Z25, Q92842	Gene names	UPF1, KIAA0221, RENT1
Domain Architecture
Description	Regulator of nonsense transcripts 1 (EC 3.6.1.-) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up- frameshift suppressor 1 homolog) (hUpf1).

RENT1_MOUSE
θ value	4.03905 (rank : 48)	NC score	0.049064 (rank : 78)
Query Neighborhood Hits	65	Target Neighborhood Hits	54	Shared Neighborhood Hits	13
SwissProt Accessions	Q9EPU0, Q99PR4	Gene names	Upf1, Rent1
Domain Architecture
Description	Regulator of nonsense transcripts 1 (EC 3.6.1.-) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up- frameshift suppressor 1 homolog) (mUpf1).

ATD3A_HUMAN
θ value	5.27518 (rank : 49)	NC score	0.084798 (rank : 52)
Query Neighborhood Hits	65	Target Neighborhood Hits	248	Shared Neighborhood Hits	38
SwissProt Accessions	Q9NVI7, Q8N275, Q96A50	Gene names	ATAD3A
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 3A.

KATL1_HUMAN
θ value	5.27518 (rank : 50)	NC score	0.094262 (rank : 42)
Query Neighborhood Hits	65	Target Neighborhood Hits	80	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BW62	Gene names	KATNAL1
Domain Architecture	No domain graphic available
Description	Katanin p60 ATPase-containing subunit A-like 1 (EC 3.6.4.3) (Katanin p60 subunit A-like 1) (p60 katanin-like 1).

KI18A_HUMAN
θ value	5.27518 (rank : 51)	NC score	0.007469 (rank : 85)
Query Neighborhood Hits	65	Target Neighborhood Hits	168	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NI77, Q86VS5, Q9H0F3	Gene names	KIF18A
Domain Architecture	No domain graphic available
Description	Kinesin family member 18A.

KTNA1_HUMAN
θ value	5.27518 (rank : 52)	NC score	0.093075 (rank : 45)
Query Neighborhood Hits	65	Target Neighborhood Hits	117	Shared Neighborhood Hits	39
SwissProt Accessions	O75449, Q5TFA8, Q5TFA9, Q86VN2, Q9NU52	Gene names	KATNA1
Domain Architecture	No domain graphic available
Description	Katanin p60 ATPase-containing subunit A1 (EC 3.6.4.3) (Katanin p60 subunit A1) (p60 katanin).

MOV10_HUMAN
θ value	5.27518 (rank : 53)	NC score	0.063854 (rank : 74)
Query Neighborhood Hits	65	Target Neighborhood Hits	46	Shared Neighborhood Hits	16
SwissProt Accessions	Q9HCE1, Q8TEF0, Q9BSY3, Q9BUJ9	Gene names	MOV10, KIAA1631
Domain Architecture
Description	Putative helicase MOV-10 (EC 3.6.1.-) (Moloney leukemia virus 10 protein).

PEX1_HUMAN
θ value	5.27518 (rank : 54)	NC score	0.097350 (rank : 40)
Query Neighborhood Hits	65	Target Neighborhood Hits	98	Shared Neighborhood Hits	40
SwissProt Accessions	O43933, Q96S71, Q96S72, Q96S73, Q99994	Gene names	PEX1
Domain Architecture
Description	Peroxisome biogenesis factor 1 (Peroxin-1) (Peroxisome biogenesis disorder protein 1).

PRS6A_HUMAN
θ value	5.27518 (rank : 55)	NC score	0.100804 (rank : 38)
Query Neighborhood Hits	65	Target Neighborhood Hits	87	Shared Neighborhood Hits	40
SwissProt Accessions	P17980, Q96HD3	Gene names	PSMC3, TBP1
Domain Architecture
Description	26S protease regulatory subunit 6A (Proteasome 26S subunit ATPase 3) (TAT-binding protein 1) (TBP-1) (Proteasome subunit P50).

PRS6A_MOUSE
θ value	5.27518 (rank : 56)	NC score	0.100818 (rank : 37)
Query Neighborhood Hits	65	Target Neighborhood Hits	85	Shared Neighborhood Hits	40
SwissProt Accessions	O88685	Gene names	Psmc3, Tbp1
Domain Architecture
Description	26S protease regulatory subunit 6A (Proteasome 26S subunit ATPase 3) (TAT-binding protein 1) (TBP-1).

REST_MOUSE
θ value	5.27518 (rank : 57)	NC score	0.001310 (rank : 88)
Query Neighborhood Hits	65	Target Neighborhood Hits	1506	Shared Neighborhood Hits	6
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

SFRS5_MOUSE
θ value	5.27518 (rank : 58)	NC score	0.013908 (rank : 81)
Query Neighborhood Hits	65	Target Neighborhood Hits	175	Shared Neighborhood Hits	3
SwissProt Accessions	O35326	Gene names	Sfrs5, Hrs
Domain Architecture
Description	Splicing factor, arginine/serine-rich 5 (Pre-mRNA-splicing factor SRP40) (Delayed-early protein HRS).

ATAD3_MOUSE
θ value	6.88961 (rank : 59)	NC score	0.084302 (rank : 53)
Query Neighborhood Hits	65	Target Neighborhood Hits	326	Shared Neighborhood Hits	40
SwissProt Accessions	Q925I1, Q3UE74, Q69ZM7, Q8C6C6	Gene names	Atad3, Atad3a, Kiaa1273
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 3 (AAA-ATPase TOB3).

BCL6B_HUMAN
θ value	8.99809 (rank : 60)	NC score	-0.001793 (rank : 89)
Query Neighborhood Hits	65	Target Neighborhood Hits	855	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N143, Q6PCB4	Gene names	BCL6B, BAZF, ZNF62
Domain Architecture	No domain graphic available
Description	B-cell CLL/lymphoma 6 member B protein (Bcl6-associated zinc finger protein) (Zinc finger protein 62).

CASP1_HUMAN
θ value	8.99809 (rank : 61)	NC score	0.010216 (rank : 83)
Query Neighborhood Hits	65	Target Neighborhood Hits	41	Shared Neighborhood Hits	3
SwissProt Accessions	P29466, Q9UCN3	Gene names	CASP1, IL1BC, IL1BCE
Domain Architecture
Description	Caspase-1 precursor (EC 3.4.22.36) (CASP-1) (Interleukin-1 beta convertase) (IL-1BC) (IL-1 beta-converting enzyme) (ICE) (Interleukin- 1 beta-converting enzyme) (p45) [Contains: Caspase-1 p20 subunit; Caspase-1 p10 subunit].

CF188_HUMAN
θ value	8.99809 (rank : 62)	NC score	0.009748 (rank : 84)
Query Neighborhood Hits	65	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N5C1	Gene names	C6orf188
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf188.

CHD5_HUMAN
θ value	8.99809 (rank : 63)	NC score	0.002573 (rank : 87)
Query Neighborhood Hits	65	Target Neighborhood Hits	349	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

MOV10_MOUSE
θ value	8.99809 (rank : 64)	NC score	0.064332 (rank : 73)
Query Neighborhood Hits	65	Target Neighborhood Hits	39	Shared Neighborhood Hits	16
SwissProt Accessions	P23249, Q9DC64	Gene names	Mov10, Gb110
Domain Architecture
Description	Putative helicase MOV-10 (EC 3.6.1.-) (Moloney leukemia virus 10 protein).

STX5_MOUSE
θ value	8.99809 (rank : 65)	NC score	0.012136 (rank : 82)
Query Neighborhood Hits	65	Target Neighborhood Hits	69	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K1E0, Q3TM79, Q99J28, Q9JKP2	Gene names	Stx5, Stx5a
Domain Architecture
Description	Syntaxin-5.

AFG31_MOUSE
θ value	θ > 10 (rank : 66)	NC score	0.080717 (rank : 66)
Query Neighborhood Hits	65	Target Neighborhood Hits	74	Shared Neighborhood Hits	36
SwissProt Accessions	Q920A7	Gene names	Afg3l1
Domain Architecture
Description	AFG3-like protein 1 (EC 3.4.24.-).

AFG32_HUMAN
θ value	θ > 10 (rank : 67)	NC score	0.079367 (rank : 67)
Query Neighborhood Hits	65	Target Neighborhood Hits	72	Shared Neighborhood Hits	36
SwissProt Accessions	Q9Y4W6	Gene names	AFG3L2
Domain Architecture
Description	AFG3-like protein 2 (EC 3.4.24.-) (Paraplegin-like protein).

AFG32_MOUSE
θ value	θ > 10 (rank : 68)	NC score	0.079338 (rank : 68)
Query Neighborhood Hits	65	Target Neighborhood Hits	73	Shared Neighborhood Hits	36
SwissProt Accessions	Q8JZQ2	Gene names	Afg3l2
Domain Architecture	No domain graphic available
Description	AFG3-like protein 2 (EC 3.4.24.-).

ATAD1_HUMAN
θ value	θ > 10 (rank : 69)	NC score	0.093484 (rank : 43)
Query Neighborhood Hits	65	Target Neighborhood Hits	75	Shared Neighborhood Hits	40
SwissProt Accessions	Q8NBU5, Q6P4B9, Q8N3G1, Q8WYR9, Q969Y3	Gene names	ATAD1
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 1.

ATAD1_MOUSE
θ value	θ > 10 (rank : 70)	NC score	0.093484 (rank : 44)
Query Neighborhood Hits	65	Target Neighborhood Hits	75	Shared Neighborhood Hits	40
SwissProt Accessions	Q9D5T0, Q3U8V2, Q9D7A4	Gene names	Atad1
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 1.

ATD3B_HUMAN
θ value	θ > 10 (rank : 71)	NC score	0.082991 (rank : 58)
Query Neighborhood Hits	65	Target Neighborhood Hits	340	Shared Neighborhood Hits	39
SwissProt Accessions	Q5T9A4, Q6ZRB5, Q9BUK4, Q9ULE7	Gene names	ATAD3B, KIAA1273
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 3B.

CDC6_MOUSE
θ value	θ > 10 (rank : 72)	NC score	0.052337 (rank : 77)
Query Neighborhood Hits	65	Target Neighborhood Hits	32	Shared Neighborhood Hits	8
SwissProt Accessions	O89033, Q3TMD0, Q8C3S5, Q9CZT0	Gene names	Cdc6
Domain Architecture	No domain graphic available
Description	Cell division control protein 6 homolog (CDC6-related protein) (p62(cdc6)).

CLPX_HUMAN
θ value	θ > 10 (rank : 73)	NC score	0.058216 (rank : 76)
Query Neighborhood Hits	65	Target Neighborhood Hits	72	Shared Neighborhood Hits	30
SwissProt Accessions	O76031, Q9H4D9	Gene names	CLPX
Domain Architecture
Description	ATP-dependent Clp protease ATP-binding subunit ClpX-like, mitochondrial precursor.

CLPX_MOUSE
θ value	θ > 10 (rank : 74)	NC score	0.058325 (rank : 75)
Query Neighborhood Hits	65	Target Neighborhood Hits	73	Shared Neighborhood Hits	30
SwissProt Accessions	Q9JHS4, Q9WVD1	Gene names	Clpx
Domain Architecture
Description	ATP-dependent Clp protease ATP-binding subunit ClpX-like, mitochondrial precursor.

FIGN_HUMAN
θ value	θ > 10 (rank : 75)	NC score	0.071870 (rank : 71)
Query Neighborhood Hits	65	Target Neighborhood Hits	176	Shared Neighborhood Hits	30
SwissProt Accessions	Q5HY92, Q9H6M5, Q9NVZ9	Gene names	FIGN
Domain Architecture	No domain graphic available
Description	Fidgetin.

FIGN_MOUSE
θ value	θ > 10 (rank : 76)	NC score	0.072412 (rank : 70)
Query Neighborhood Hits	65	Target Neighborhood Hits	165	Shared Neighborhood Hits	30
SwissProt Accessions	Q9ERZ6, Q3TPB0, Q3UP57, Q6PCM0	Gene names	Fign
Domain Architecture	No domain graphic available
Description	Fidgetin.

NSF_HUMAN
θ value	θ > 10 (rank : 77)	NC score	0.086133 (rank : 50)
Query Neighborhood Hits	65	Target Neighborhood Hits	74	Shared Neighborhood Hits	39
SwissProt Accessions	P46459, Q9UKZ2	Gene names	NSF
Domain Architecture
Description	Vesicle-fusing ATPase (EC 3.6.4.6) (Vesicular-fusion protein NSF) (N- ethylmaleimide sensitive fusion protein) (NEM-sensitive fusion protein).

NSF_MOUSE
θ value	θ > 10 (rank : 78)	NC score	0.086031 (rank : 51)
Query Neighborhood Hits	65	Target Neighborhood Hits	73	Shared Neighborhood Hits	39
SwissProt Accessions	P46460	Gene names	Nsf, Skd2
Domain Architecture
Description	Vesicle-fusing ATPase (EC 3.6.4.6) (Vesicular-fusion protein NSF) (N- ethylmaleimide sensitive fusion protein) (NEM-sensitive fusion protein) (SKD2 protein).

PRS4_HUMAN
θ value	θ > 10 (rank : 79)	NC score	0.089972 (rank : 47)
Query Neighborhood Hits	65	Target Neighborhood Hits	84	Shared Neighborhood Hits	40
SwissProt Accessions	P62191, P49014, Q03527, Q6IAW0, Q96AZ3	Gene names	PSMC1
Domain Architecture
Description	26S protease regulatory subunit 4 (P26s4) (Proteasome 26S subunit ATPase 1).

PRS4_MOUSE
θ value	θ > 10 (rank : 80)	NC score	0.089972 (rank : 48)
Query Neighborhood Hits	65	Target Neighborhood Hits	84	Shared Neighborhood Hits	40
SwissProt Accessions	P62192, P49014, Q03527, Q96AZ3	Gene names	Psmc1
Domain Architecture
Description	26S protease regulatory subunit 4 (P26s4) (Proteasome 26S subunit ATPase 1).

PRS6B_HUMAN
θ value	θ > 10 (rank : 81)	NC score	0.081594 (rank : 61)
Query Neighborhood Hits	65	Target Neighborhood Hits	85	Shared Neighborhood Hits	34
SwissProt Accessions	P43686, Q96FV5, Q9UBM3, Q9UEX3	Gene names	PSMC4, TBP7
Domain Architecture
Description	26S protease regulatory subunit 6B (Proteasome 26S subunit ATPase 4) (MIP224) (MB67-interacting protein) (TAT-binding protein 7) (TBP-7).

PRS6B_MOUSE
θ value	θ > 10 (rank : 82)	NC score	0.081547 (rank : 62)
Query Neighborhood Hits	65	Target Neighborhood Hits	89	Shared Neighborhood Hits	34
SwissProt Accessions	P54775	Gene names	Psmc4, Tbp7
Domain Architecture
Description	26S protease regulatory subunit 6B (Proteasome 26S subunit ATPase 4) (MIP224) (MB67-interacting protein) (TAT-binding protein 7) (TBP-7) (CIP21).

PRS7_HUMAN
θ value	θ > 10 (rank : 83)	NC score	0.080791 (rank : 64)
Query Neighborhood Hits	65	Target Neighborhood Hits	66	Shared Neighborhood Hits	35
SwissProt Accessions	P35998	Gene names	PSMC2, MSS1
Domain Architecture
Description	26S protease regulatory subunit 7 (Proteasome 26S subunit ATPase 2) (Protein MSS1).

PRS7_MOUSE
θ value	θ > 10 (rank : 84)	NC score	0.080790 (rank : 65)
Query Neighborhood Hits	65	Target Neighborhood Hits	67	Shared Neighborhood Hits	35
SwissProt Accessions	P46471, O08531, Q3TGX5, Q9DBA1	Gene names	Psmc2, Mss1
Domain Architecture
Description	26S protease regulatory subunit 7 (Proteasome 26S subunit ATPase 2) (Protein MSS1).

PRS8_HUMAN
θ value	θ > 10 (rank : 85)	NC score	0.084139 (rank : 54)
Query Neighborhood Hits	65	Target Neighborhood Hits	117	Shared Neighborhood Hits	41
SwissProt Accessions	P62195, O35051, O43208, P47210, P52915, P52916	Gene names	PSMC5, SUG1
Domain Architecture
Description	26S protease regulatory subunit 8 (Proteasome 26S subunit ATPase 5) (Proteasome subunit p45) (p45/SUG) (Thyroid hormone receptor- interacting protein 1) (TRIP1).

PRS8_MOUSE
θ value	θ > 10 (rank : 86)	NC score	0.084139 (rank : 55)
Query Neighborhood Hits	65	Target Neighborhood Hits	117	Shared Neighborhood Hits	41
SwissProt Accessions	P62196, O35051, P47210, P52915, P52916, Q3UL51, Q9CWN5	Gene names	Psmc5, Sug1
Domain Architecture
Description	26S protease regulatory subunit 8 (Proteasome 26S subunit ATPase 5) (Proteasome subunit p45) (p45/SUG) (mSUG1).

SPAST_HUMAN
θ value	θ > 10 (rank : 87)	NC score	0.082209 (rank : 60)
Query Neighborhood Hits	65	Target Neighborhood Hits	100	Shared Neighborhood Hits	36
SwissProt Accessions	Q9UBP0, Q9UPR9	Gene names	SPAST, KIAA1083, SPG4
Domain Architecture
Description	Spastin.

SPAST_MOUSE
θ value	θ > 10 (rank : 88)	NC score	0.082292 (rank : 59)
Query Neighborhood Hits	65	Target Neighborhood Hits	138	Shared Neighborhood Hits	36
SwissProt Accessions	Q9QYY8, Q6ZPY6, Q80VE0, Q9CVK0	Gene names	Spast, Kiaa1083, Spg4
Domain Architecture	No domain graphic available
Description	Spastin.

SPG7_HUMAN
θ value	θ > 10 (rank : 89)	NC score	0.080797 (rank : 63)
Query Neighborhood Hits	65	Target Neighborhood Hits	71	Shared Neighborhood Hits	36
SwissProt Accessions	Q9UQ90, O75756, Q96IB0	Gene names	SPG7, CAR, CMAR, PGN
Domain Architecture
Description	Paraplegin (EC 3.4.24.-) (Spastic paraplegia protein 7).

Hits sorted by NC score

RFC4_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	65	Target Neighborhood Hits	65	Shared Neighborhood Hits	65
SwissProt Accessions	Q99J62	Gene names	Rfc4
Domain Architecture	No domain graphic available
Description	Replication factor C subunit 4.

RFC4_HUMAN
NC score	0.997743 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	65	Target Neighborhood Hits	64	Shared Neighborhood Hits	59
SwissProt Accessions	P35249, Q6FHX7	Gene names	RFC4
Domain Architecture
Description	Replication factor C subunit 4 (Replication factor C 37 kDa subunit) (RF-C 37 kDa subunit) (RFC37) (Activator 1 37 kDa subunit) (A1 37 kDa subunit).

RFC5_MOUSE
NC score	0.927803 (rank : 3)	θ value	3.36421e-55 (rank : 4)
Query Neighborhood Hits	65	Target Neighborhood Hits	58	Shared Neighborhood Hits	40
SwissProt Accessions	Q9D0F6	Gene names	Rfc5
Domain Architecture
Description	Replication factor C subunit 5 (Replication factor C 36 kDa subunit) (RF-C 36 kDa subunit) (RFC36) (Activator 1 36 kDa subunit) (A1 36 kDa subunit).

RFC5_HUMAN
NC score	0.925909 (rank : 4)	θ value	1.15626e-55 (rank : 3)
Query Neighborhood Hits	65	Target Neighborhood Hits	60	Shared Neighborhood Hits	38
SwissProt Accessions	P40937	Gene names	RFC5
Domain Architecture
Description	Replication factor C subunit 5 (Replication factor C 36 kDa subunit) (RF-C 36 kDa subunit) (RFC36) (Activator 1 36 kDa subunit) (A1 36 kDa subunit).

RFC2_HUMAN
NC score	0.909806 (rank : 5)	θ value	3.04986e-48 (rank : 5)
Query Neighborhood Hits	65	Target Neighborhood Hits	46	Shared Neighborhood Hits	27
SwissProt Accessions	P35250, P32846, Q9BU93	Gene names	RFC2
Domain Architecture
Description	Replication factor C subunit 2 (Replication factor C 40 kDa subunit) (RF-C 40 kDa subunit) (RFC40) (Activator 1 40 kDa subunit) (A1 40 kDa subunit).

RFC2_MOUSE
NC score	0.909169 (rank : 6)	θ value	3.98324e-48 (rank : 6)
Query Neighborhood Hits	65	Target Neighborhood Hits	46	Shared Neighborhood Hits	27
SwissProt Accessions	Q9WUK4	Gene names	Rfc2
Domain Architecture
Description	Replication factor C subunit 2 (Replication factor C 40 kDa subunit) (RF-C 40 kDa subunit) (RFC40) (Activator 1 40 kDa subunit) (A1 40 kDa subunit).

RFC3_MOUSE
NC score	0.790293 (rank : 7)	θ value	1.80048e-24 (rank : 8)
Query Neighborhood Hits	65	Target Neighborhood Hits	18	Shared Neighborhood Hits	14
SwissProt Accessions	Q8R323	Gene names	Rfc3
Domain Architecture
Description	Replication factor C subunit 3 (Replication factor C 38 kDa subunit) (RFC38) (Activator 1 38 kDa subunit) (A1 38 kDa subunit) (RF-C 38 kDa subunit).

RFC3_HUMAN
NC score	0.788078 (rank : 8)	θ value	1.37858e-24 (rank : 7)
Query Neighborhood Hits	65	Target Neighborhood Hits	16	Shared Neighborhood Hits	14
SwissProt Accessions	P40938, O15252	Gene names	RFC3
Domain Architecture
Description	Replication factor C subunit 3 (Replication factor C 38 kDa subunit) (RFC38) (Activator 1 38 kDa subunit) (A1 38 kDa subunit) (RF-C 38 kDa subunit).

RFC1_MOUSE
NC score	0.363056 (rank : 9)	θ value	0.000121331 (rank : 10)
Query Neighborhood Hits	65	Target Neighborhood Hits	290	Shared Neighborhood Hits	37
SwissProt Accessions	P35601	Gene names	Rfc1, Ibf-1, Recc1
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (A1-P145) (Differentiation- specific element-binding protein) (ISRE-binding protein).

RFC1_HUMAN
NC score	0.355331 (rank : 10)	θ value	8.40245e-06 (rank : 9)
Query Neighborhood Hits	65	Target Neighborhood Hits	352	Shared Neighborhood Hits	36
SwissProt Accessions	P35251, Q5XKF5, Q6PKU0, Q86V41, Q86V46	Gene names	RFC1, RFC140
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (DNA-binding protein PO-GA).

RAD17_MOUSE
NC score	0.332373 (rank : 11)	θ value	0.00390308 (rank : 11)
Query Neighborhood Hits	65	Target Neighborhood Hits	63	Shared Neighborhood Hits	27
SwissProt Accessions	Q6NXW6, O88934, O89024	Gene names	Rad17
Domain Architecture	No domain graphic available
Description	Cell cycle checkpoint protein RAD17.

WRIP1_MOUSE
NC score	0.323715 (rank : 12)	θ value	0.00390308 (rank : 12)
Query Neighborhood Hits	65	Target Neighborhood Hits	93	Shared Neighborhood Hits	37
SwissProt Accessions	Q91XU0, Q3TCT7, Q6PDF0, Q8BUW5, Q8BWP6, Q8BY55, Q921W3, Q9EQL3	Gene names	Wrnip1, Whip
Domain Architecture	No domain graphic available
Description	ATPase WRNIP1 (Werner helicase-interacting protein 1).

RAD17_HUMAN
NC score	0.300151 (rank : 13)	θ value	0.0113563 (rank : 13)
Query Neighborhood Hits	65	Target Neighborhood Hits	44	Shared Neighborhood Hits	21
SwissProt Accessions	O75943, O75714, Q7Z3S4, Q9UNK7, Q9UNR7, Q9UNR8, Q9UPF5	Gene names	RAD17, R24L
Domain Architecture	No domain graphic available
Description	Cell cycle checkpoint protein RAD17 (hRad17) (RF-C/activator 1 homolog).

WRIP1_HUMAN
NC score	0.289182 (rank : 14)	θ value	0.0252991 (rank : 14)
Query Neighborhood Hits	65	Target Neighborhood Hits	100	Shared Neighborhood Hits	37
SwissProt Accessions	Q96S55, Q53EP6, Q59ET8, Q5W0E2, Q5W0E4, Q8WV26, Q9H681, Q9NRJ6	Gene names	WRNIP1, WHIP
Domain Architecture	No domain graphic available
Description	ATPase WRNIP1 (Werner helicase-interacting protein 1).

LONM_HUMAN
NC score	0.128525 (rank : 15)	θ value	0.365318 (rank : 20)
Query Neighborhood Hits	65	Target Neighborhood Hits	130	Shared Neighborhood Hits	36
SwissProt Accessions	P36776, P36777, Q9UQ95	Gene names	PRSS15
Domain Architecture
Description	Lon protease homolog, mitochondrial precursor (EC 3.4.21.-) (Lon protease-like protein) (LONP) (LONHs).

NVL_MOUSE
NC score	0.123960 (rank : 16)	θ value	0.21417 (rank : 18)
Query Neighborhood Hits	65	Target Neighborhood Hits	110	Shared Neighborhood Hits	42
SwissProt Accessions	Q9DBY8, Q3USC4, Q8BW27, Q8K2B5	Gene names	Nvl
Domain Architecture
Description	Nuclear valosin-containing protein-like (Nuclear VCP-like protein) (NVLp).

NVL_HUMAN
NC score	0.123347 (rank : 17)	θ value	0.365318 (rank : 21)
Query Neighborhood Hits	65	Target Neighborhood Hits	112	Shared Neighborhood Hits	44
SwissProt Accessions	O15381, Q96EM7	Gene names	NVL
Domain Architecture
Description	Nuclear valosin-containing protein-like (Nuclear VCP-like protein) (NVLp).

PRS10_HUMAN
NC score	0.120975 (rank : 18)	θ value	0.0961366 (rank : 15)
Query Neighborhood Hits	65	Target Neighborhood Hits	95	Shared Neighborhood Hits	44
SwissProt Accessions	P62333, P49719, Q6IBU3, Q92524	Gene names	PSMC6, SUG2
Domain Architecture
Description	26S protease regulatory subunit S10B (Proteasome subunit p42) (Proteasome 26S subunit ATPase 6).

PRS10_MOUSE
NC score	0.120975 (rank : 19)	θ value	0.0961366 (rank : 16)
Query Neighborhood Hits	65	Target Neighborhood Hits	95	Shared Neighborhood Hits	44
SwissProt Accessions	P62334, P49719, Q3TKK1, Q810A6, Q92524, Q9CXH9	Gene names	Psmc6, Sug2
Domain Architecture
Description	26S protease regulatory subunit S10B (Proteasome subunit p42) (Proteasome 26S subunit ATPase 6).

CDC6_HUMAN
NC score	0.120908 (rank : 20)	θ value	0.279714 (rank : 19)
Query Neighborhood Hits	65	Target Neighborhood Hits	30	Shared Neighborhood Hits	12
SwissProt Accessions	Q99741, Q8TB30	Gene names	CDC6, CDC18L
Domain Architecture	No domain graphic available
Description	Cell division control protein 6 homolog (CDC6-related protein) (p62(cdc6)) (HsCDC6) (HsCDC18).

TRP13_MOUSE
NC score	0.114947 (rank : 21)	θ value	1.81305 (rank : 33)
Query Neighborhood Hits	65	Target Neighborhood Hits	81	Shared Neighborhood Hits	37
SwissProt Accessions	Q3UA06, Q3UQG6, Q9CWW8	Gene names	Trip13
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 13 (Thyroid hormone receptor interactor 13) (Trip-13).

TERA_MOUSE
NC score	0.114459 (rank : 22)	θ value	0.62314 (rank : 23)
Query Neighborhood Hits	65	Target Neighborhood Hits	76	Shared Neighborhood Hits	41
SwissProt Accessions	Q01853	Gene names	Vcp
Domain Architecture
Description	Transitional endoplasmic reticulum ATPase (TER ATPase) (15S Mg(2+)- ATPase p97 subunit) (Valosin-containing protein) (VCP).

TERA_HUMAN
NC score	0.114440 (rank : 23)	θ value	0.62314 (rank : 22)
Query Neighborhood Hits	65	Target Neighborhood Hits	76	Shared Neighborhood Hits	41
SwissProt Accessions	P55072, Q969G7	Gene names	VCP
Domain Architecture
Description	Transitional endoplasmic reticulum ATPase (TER ATPase) (15S Mg(2+)- ATPase p97 subunit) (Valosin-containing protein) (VCP).

PEX6_HUMAN
NC score	0.114096 (rank : 24)	θ value	0.813845 (rank : 26)
Query Neighborhood Hits	65	Target Neighborhood Hits	99	Shared Neighborhood Hits	44
SwissProt Accessions	Q13608, Q8WYQ2, Q99476	Gene names	PEX6, PXAAA1
Domain Architecture
Description	Peroxisome assembly factor 2 (PAF-2) (Peroxisomal-type ATPase 1) (Peroxin-6) (Peroxisomal biogenesis factor 6).

TRP13_HUMAN
NC score	0.113896 (rank : 25)	θ value	1.81305 (rank : 32)
Query Neighborhood Hits	65	Target Neighborhood Hits	81	Shared Neighborhood Hits	37
SwissProt Accessions	Q15645, O15324	Gene names	TRIP13
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 13 (Thyroid hormone receptor interactor 13) (Trip-13) (Human papillomavirus type 16 E1 protein- binding protein) (HPV16 E1 protein-binding protein) (16E1-BP).

PEX6_MOUSE
NC score	0.113732 (rank : 26)	θ value	1.06291 (rank : 28)
Query Neighborhood Hits	65	Target Neighborhood Hits	94	Shared Neighborhood Hits	42
SwissProt Accessions	Q99LC9, Q6YNQ9	Gene names	Pex6
Domain Architecture	No domain graphic available
Description	Peroxisome assembly factor 2 (PAF-2) (Peroxisomal-type ATPase 1) (Peroxin-6) (Peroxisomal biogenesis factor 6).

BCS1_HUMAN
NC score	0.110501 (rank : 27)	θ value	3.0926 (rank : 41)
Query Neighborhood Hits	65	Target Neighborhood Hits	61	Shared Neighborhood Hits	36
SwissProt Accessions	Q9Y276, Q7Z2V7	Gene names	BCS1L, BCS1
Domain Architecture
Description	Mitochondrial chaperone BCS1 (BCS1-like protein) (H-BCS1).

YMEL1_HUMAN
NC score	0.106573 (rank : 28)	θ value	1.81305 (rank : 34)
Query Neighborhood Hits	65	Target Neighborhood Hits	73	Shared Neighborhood Hits	37
SwissProt Accessions	Q96TA2, Q9H1Q0, Q9UMR9	Gene names	YME1L1, FTSH1, YME1L
Domain Architecture
Description	ATP-dependent metalloprotease YME1L1 (EC 3.4.24.-) (YME1-like protein 1) (ATP-dependent metalloprotease FtsH1) (Meg-4) (Presenilin- associated metalloprotease) (PAMP).

YMEL1_MOUSE
NC score	0.105288 (rank : 29)	θ value	2.36792 (rank : 40)
Query Neighborhood Hits	65	Target Neighborhood Hits	76	Shared Neighborhood Hits	37
SwissProt Accessions	O88967, Q7TNN5	Gene names	Yme1l1
Domain Architecture
Description	ATP-dependent metalloprotease YME1L1 (EC 3.4.24.-) (YME1-like protein 1) (ATP-dependent metalloprotease FtsH1).

VPS4B_HUMAN
NC score	0.104273 (rank : 30)	θ value	0.62314 (rank : 24)
Query Neighborhood Hits	65	Target Neighborhood Hits	87	Shared Neighborhood Hits	38
SwissProt Accessions	O75351, Q9GZS7	Gene names	VPS4B, SKD1, VPS42
Domain Architecture
Description	Vacuolar protein sorting-associating protein 4B (Protein SKD1).

VPS4B_MOUSE
NC score	0.103501 (rank : 31)	θ value	0.62314 (rank : 25)
Query Neighborhood Hits	65	Target Neighborhood Hits	86	Shared Neighborhood Hits	37
SwissProt Accessions	P46467, Q91W22, Q9R1C9	Gene names	Vps4b, Skd1
Domain Architecture
Description	Vacuolar protein sorting-associating protein 4B (Protein SKD1).

RUVB1_HUMAN
NC score	0.101697 (rank : 32)	θ value	2.36792 (rank : 38)
Query Neighborhood Hits	65	Target Neighborhood Hits	78	Shared Neighborhood Hits	40
SwissProt Accessions	Q9Y265, Q9BSX9	Gene names	RUVBL1, NMP238, TIP49, TIP49A
Domain Architecture
Description	RuvB-like 1 (EC 3.6.1.-) (49 kDa TATA box-binding protein-interacting protein) (49 kDa TBP-interacting protein) (TIP49a) (Pontin 52) (Nuclear matrix protein 238) (NMP 238) (54 kDa erythrocyte cytosolic protein) (ECP-54) (TIP60-associated protein 54-alpha) (TAP54-alpha).

RUVB1_MOUSE
NC score	0.101684 (rank : 33)	θ value	2.36792 (rank : 39)
Query Neighborhood Hits	65	Target Neighborhood Hits	78	Shared Neighborhood Hits	40
SwissProt Accessions	P60122, O35753	Gene names	Ruvbl1, Tip49, Tip49a
Domain Architecture
Description	RuvB-like 1 (EC 3.6.1.-) (49 kDa TATA box-binding protein-interacting protein) (49 kDa TBP-interacting protein) (TIP49a) (Pontin 52) (DNA helicase p50).

BCS1_MOUSE
NC score	0.101360 (rank : 34)	θ value	3.0926 (rank : 42)
Query Neighborhood Hits	65	Target Neighborhood Hits	64	Shared Neighborhood Hits	36
SwissProt Accessions	Q9CZP5	Gene names	Bcs1l
Domain Architecture
Description	Mitochondrial chaperone BCS1 (BCS1-like protein).

VPS4A_HUMAN
NC score	0.100884 (rank : 35)	θ value	3.0926 (rank : 44)
Query Neighborhood Hits	65	Target Neighborhood Hits	95	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UN37, Q8TF07, Q9UI03, Q9Y582	Gene names	VPS4A, VPS4
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associating protein 4A (SKD2 protein) (hVPS4) (VPS4-1).

VPS4A_MOUSE
NC score	0.100879 (rank : 36)	θ value	3.0926 (rank : 45)
Query Neighborhood Hits	65	Target Neighborhood Hits	94	Shared Neighborhood Hits	40
SwissProt Accessions	Q8VEJ9, Q3TXT2	Gene names	Vps4a
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associating protein 4A.

PRS6A_MOUSE
NC score	0.100818 (rank : 37)	θ value	5.27518 (rank : 56)
Query Neighborhood Hits	65	Target Neighborhood Hits	85	Shared Neighborhood Hits	40
SwissProt Accessions	O88685	Gene names	Psmc3, Tbp1
Domain Architecture
Description	26S protease regulatory subunit 6A (Proteasome 26S subunit ATPase 3) (TAT-binding protein 1) (TBP-1).

PRS6A_HUMAN
NC score	0.100804 (rank : 38)	θ value	5.27518 (rank : 55)
Query Neighborhood Hits	65	Target Neighborhood Hits	87	Shared Neighborhood Hits	40
SwissProt Accessions	P17980, Q96HD3	Gene names	PSMC3, TBP1
Domain Architecture
Description	26S protease regulatory subunit 6A (Proteasome 26S subunit ATPase 3) (TAT-binding protein 1) (TBP-1) (Proteasome subunit P50).

KATL1_MOUSE
NC score	0.097640 (rank : 39)	θ value	2.36792 (rank : 35)
Query Neighborhood Hits	65	Target Neighborhood Hits	77	Shared Neighborhood Hits	38
SwissProt Accessions	Q8K0T4	Gene names	Katnal1
Domain Architecture	No domain graphic available
Description	Katanin p60 ATPase-containing subunit A-like 1 (EC 3.6.4.3) (Katanin p60 subunit A-like 1) (p60 katanin-like 1).

PEX1_HUMAN
NC score	0.097350 (rank : 40)	θ value	5.27518 (rank : 54)
Query Neighborhood Hits	65	Target Neighborhood Hits	98	Shared Neighborhood Hits	40
SwissProt Accessions	O43933, Q96S71, Q96S72, Q96S73, Q99994	Gene names	PEX1
Domain Architecture
Description	Peroxisome biogenesis factor 1 (Peroxin-1) (Peroxisome biogenesis disorder protein 1).

KTNA1_MOUSE
NC score	0.097165 (rank : 41)	θ value	2.36792 (rank : 36)
Query Neighborhood Hits	65	Target Neighborhood Hits	123	Shared Neighborhood Hits	38
SwissProt Accessions	Q9WV86	Gene names	Katna1
Domain Architecture	No domain graphic available
Description	Katanin p60 ATPase-containing subunit A1 (EC 3.6.4.3) (Katanin p60 subunit A1) (p60 katanin) (Lipotransin).

KATL1_HUMAN
NC score	0.094262 (rank : 42)	θ value	5.27518 (rank : 50)
Query Neighborhood Hits	65	Target Neighborhood Hits	80	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BW62	Gene names	KATNAL1
Domain Architecture	No domain graphic available
Description	Katanin p60 ATPase-containing subunit A-like 1 (EC 3.6.4.3) (Katanin p60 subunit A-like 1) (p60 katanin-like 1).

ATAD1_HUMAN
NC score	0.093484 (rank : 43)	θ value	θ > 10 (rank : 69)
Query Neighborhood Hits	65	Target Neighborhood Hits	75	Shared Neighborhood Hits	40
SwissProt Accessions	Q8NBU5, Q6P4B9, Q8N3G1, Q8WYR9, Q969Y3	Gene names	ATAD1
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 1.

ATAD1_MOUSE
NC score	0.093484 (rank : 44)	θ value	θ > 10 (rank : 70)
Query Neighborhood Hits	65	Target Neighborhood Hits	75	Shared Neighborhood Hits	40
SwissProt Accessions	Q9D5T0, Q3U8V2, Q9D7A4	Gene names	Atad1
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 1.

KTNA1_HUMAN
NC score	0.093075 (rank : 45)	θ value	5.27518 (rank : 52)
Query Neighborhood Hits	65	Target Neighborhood Hits	117	Shared Neighborhood Hits	39
SwissProt Accessions	O75449, Q5TFA8, Q5TFA9, Q86VN2, Q9NU52	Gene names	KATNA1
Domain Architecture	No domain graphic available
Description	Katanin p60 ATPase-containing subunit A1 (EC 3.6.4.3) (Katanin p60 subunit A1) (p60 katanin).

ATAD2_MOUSE
NC score	0.091670 (rank : 46)	θ value	1.81305 (rank : 31)
Query Neighborhood Hits	65	Target Neighborhood Hits	167	Shared Neighborhood Hits	37
SwissProt Accessions	Q8CDM1	Gene names	Atad2
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 2.

PRS4_HUMAN
NC score	0.089972 (rank : 47)	θ value	θ > 10 (rank : 79)
Query Neighborhood Hits	65	Target Neighborhood Hits	84	Shared Neighborhood Hits	40
SwissProt Accessions	P62191, P49014, Q03527, Q6IAW0, Q96AZ3	Gene names	PSMC1
Domain Architecture
Description	26S protease regulatory subunit 4 (P26s4) (Proteasome 26S subunit ATPase 1).

PRS4_MOUSE
NC score	0.089972 (rank : 48)	θ value	θ > 10 (rank : 80)
Query Neighborhood Hits	65	Target Neighborhood Hits	84	Shared Neighborhood Hits	40
SwissProt Accessions	P62192, P49014, Q03527, Q96AZ3	Gene names	Psmc1
Domain Architecture
Description	26S protease regulatory subunit 4 (P26s4) (Proteasome 26S subunit ATPase 1).

ATAD2_HUMAN
NC score	0.089793 (rank : 49)	θ value	1.81305 (rank : 30)
Query Neighborhood Hits	65	Target Neighborhood Hits	322	Shared Neighborhood Hits	37
SwissProt Accessions	Q6PL18, Q658P2, Q68CQ0, Q6PJV6, Q8N890, Q9UHS5	Gene names	ATAD2
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 2.

NSF_HUMAN
NC score	0.086133 (rank : 50)	θ value	θ > 10 (rank : 77)
Query Neighborhood Hits	65	Target Neighborhood Hits	74	Shared Neighborhood Hits	39
SwissProt Accessions	P46459, Q9UKZ2	Gene names	NSF
Domain Architecture
Description	Vesicle-fusing ATPase (EC 3.6.4.6) (Vesicular-fusion protein NSF) (N- ethylmaleimide sensitive fusion protein) (NEM-sensitive fusion protein).

NSF_MOUSE
NC score	0.086031 (rank : 51)	θ value	θ > 10 (rank : 78)
Query Neighborhood Hits	65	Target Neighborhood Hits	73	Shared Neighborhood Hits	39
SwissProt Accessions	P46460	Gene names	Nsf, Skd2
Domain Architecture
Description	Vesicle-fusing ATPase (EC 3.6.4.6) (Vesicular-fusion protein NSF) (N- ethylmaleimide sensitive fusion protein) (NEM-sensitive fusion protein) (SKD2 protein).

ATD3A_HUMAN
NC score	0.084798 (rank : 52)	θ value	5.27518 (rank : 49)
Query Neighborhood Hits	65	Target Neighborhood Hits	248	Shared Neighborhood Hits	38
SwissProt Accessions	Q9NVI7, Q8N275, Q96A50	Gene names	ATAD3A
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 3A.

ATAD3_MOUSE
NC score	0.084302 (rank : 53)	θ value	6.88961 (rank : 59)
Query Neighborhood Hits	65	Target Neighborhood Hits	326	Shared Neighborhood Hits	40
SwissProt Accessions	Q925I1, Q3UE74, Q69ZM7, Q8C6C6	Gene names	Atad3, Atad3a, Kiaa1273
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 3 (AAA-ATPase TOB3).

PRS8_HUMAN
NC score	0.084139 (rank : 54)	θ value	θ > 10 (rank : 85)
Query Neighborhood Hits	65	Target Neighborhood Hits	117	Shared Neighborhood Hits	41
SwissProt Accessions	P62195, O35051, O43208, P47210, P52915, P52916	Gene names	PSMC5, SUG1
Domain Architecture
Description	26S protease regulatory subunit 8 (Proteasome 26S subunit ATPase 5) (Proteasome subunit p45) (p45/SUG) (Thyroid hormone receptor- interacting protein 1) (TRIP1).

PRS8_MOUSE
NC score	0.084139 (rank : 55)	θ value	θ > 10 (rank : 86)
Query Neighborhood Hits	65	Target Neighborhood Hits	117	Shared Neighborhood Hits	41
SwissProt Accessions	P62196, O35051, P47210, P52915, P52916, Q3UL51, Q9CWN5	Gene names	Psmc5, Sug1
Domain Architecture
Description	26S protease regulatory subunit 8 (Proteasome 26S subunit ATPase 5) (Proteasome subunit p45) (p45/SUG) (mSUG1).

M10L1_HUMAN
NC score	0.084057 (rank : 56)	θ value	2.36792 (rank : 37)
Query Neighborhood Hits	65	Target Neighborhood Hits	36	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BXT6, Q5TGD5, Q8NBD4, Q9NXW3, Q9UFB3, Q9UGX9	Gene names	MOV10L1
Domain Architecture
Description	Putative helicase Mov10l1 (EC 3.6.1.-) (Moloney leukemia virus 10-like protein 1) (MOV10-like 1).

M10L1_MOUSE
NC score	0.084022 (rank : 57)	θ value	0.125558 (rank : 17)
Query Neighborhood Hits	65	Target Neighborhood Hits	59	Shared Neighborhood Hits	12
SwissProt Accessions	Q99MV5, Q7TPA9, Q8C3W0, Q924C2	Gene names	Mov10l1, Champ
Domain Architecture
Description	Putative helicase Mov10l1 (EC 3.6.1.-) (Moloney leukemia virus 10-like protein 1) (MOV10-like 1) (Cardiac helicase activated by MEF2 protein) (Cardiac-specific RNA helicase).

ATD3B_HUMAN
NC score	0.082991 (rank : 58)	θ value	θ > 10 (rank : 71)
Query Neighborhood Hits	65	Target Neighborhood Hits	340	Shared Neighborhood Hits	39
SwissProt Accessions	Q5T9A4, Q6ZRB5, Q9BUK4, Q9ULE7	Gene names	ATAD3B, KIAA1273
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 3B.

SPAST_MOUSE
NC score	0.082292 (rank : 59)	θ value	θ > 10 (rank : 88)
Query Neighborhood Hits	65	Target Neighborhood Hits	138	Shared Neighborhood Hits	36
SwissProt Accessions	Q9QYY8, Q6ZPY6, Q80VE0, Q9CVK0	Gene names	Spast, Kiaa1083, Spg4
Domain Architecture	No domain graphic available
Description	Spastin.

SPAST_HUMAN
NC score	0.082209 (rank : 60)	θ value	θ > 10 (rank : 87)
Query Neighborhood Hits	65	Target Neighborhood Hits	100	Shared Neighborhood Hits	36
SwissProt Accessions	Q9UBP0, Q9UPR9	Gene names	SPAST, KIAA1083, SPG4
Domain Architecture
Description	Spastin.

PRS6B_HUMAN
NC score	0.081594 (rank : 61)	θ value	θ > 10 (rank : 81)
Query Neighborhood Hits	65	Target Neighborhood Hits	85	Shared Neighborhood Hits	34
SwissProt Accessions	P43686, Q96FV5, Q9UBM3, Q9UEX3	Gene names	PSMC4, TBP7
Domain Architecture
Description	26S protease regulatory subunit 6B (Proteasome 26S subunit ATPase 4) (MIP224) (MB67-interacting protein) (TAT-binding protein 7) (TBP-7).

PRS6B_MOUSE
NC score	0.081547 (rank : 62)	θ value	θ > 10 (rank : 82)
Query Neighborhood Hits	65	Target Neighborhood Hits	89	Shared Neighborhood Hits	34
SwissProt Accessions	P54775	Gene names	Psmc4, Tbp7
Domain Architecture
Description	26S protease regulatory subunit 6B (Proteasome 26S subunit ATPase 4) (MIP224) (MB67-interacting protein) (TAT-binding protein 7) (TBP-7) (CIP21).

SPG7_HUMAN
NC score	0.080797 (rank : 63)	θ value	θ > 10 (rank : 89)
Query Neighborhood Hits	65	Target Neighborhood Hits	71	Shared Neighborhood Hits	36
SwissProt Accessions	Q9UQ90, O75756, Q96IB0	Gene names	SPG7, CAR, CMAR, PGN
Domain Architecture
Description	Paraplegin (EC 3.4.24.-) (Spastic paraplegia protein 7).

PRS7_HUMAN
NC score	0.080791 (rank : 64)	θ value	θ > 10 (rank : 83)
Query Neighborhood Hits	65	Target Neighborhood Hits	66	Shared Neighborhood Hits	35
SwissProt Accessions	P35998	Gene names	PSMC2, MSS1
Domain Architecture
Description	26S protease regulatory subunit 7 (Proteasome 26S subunit ATPase 2) (Protein MSS1).

PRS7_MOUSE
NC score	0.080790 (rank : 65)	θ value	θ > 10 (rank : 84)
Query Neighborhood Hits	65	Target Neighborhood Hits	67	Shared Neighborhood Hits	35
SwissProt Accessions	P46471, O08531, Q3TGX5, Q9DBA1	Gene names	Psmc2, Mss1
Domain Architecture
Description	26S protease regulatory subunit 7 (Proteasome 26S subunit ATPase 2) (Protein MSS1).

AFG31_MOUSE
NC score	0.080717 (rank : 66)	θ value	θ > 10 (rank : 66)
Query Neighborhood Hits	65	Target Neighborhood Hits	74	Shared Neighborhood Hits	36
SwissProt Accessions	Q920A7	Gene names	Afg3l1
Domain Architecture
Description	AFG3-like protein 1 (EC 3.4.24.-).

AFG32_HUMAN
NC score	0.079367 (rank : 67)	θ value	θ > 10 (rank : 67)
Query Neighborhood Hits	65	Target Neighborhood Hits	72	Shared Neighborhood Hits	36
SwissProt Accessions	Q9Y4W6	Gene names	AFG3L2
Domain Architecture
Description	AFG3-like protein 2 (EC 3.4.24.-) (Paraplegin-like protein).

AFG32_MOUSE
NC score	0.079338 (rank : 68)	θ value	θ > 10 (rank : 68)
Query Neighborhood Hits	65	Target Neighborhood Hits	73	Shared Neighborhood Hits	36
SwissProt Accessions	Q8JZQ2	Gene names	Afg3l2
Domain Architecture	No domain graphic available
Description	AFG3-like protein 2 (EC 3.4.24.-).

PR285_HUMAN
NC score	0.075108 (rank : 69)	θ value	0.813845 (rank : 27)
Query Neighborhood Hits	65	Target Neighborhood Hits	63	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BYK8, Q3C2G2, Q4VXQ1, Q8TEF3, Q96ND3, Q9C094	Gene names	PRIC285, KIAA1769
Domain Architecture
Description	Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein (EC 3.6.1.-) (ATP-dependent helicase PRIC285) (PPAR-alpha- interacting complex protein 285) (PPAR-gamma DBD-interacting protein 1) (PDIP1).

FIGN_MOUSE
NC score	0.072412 (rank : 70)	θ value	θ > 10 (rank : 76)
Query Neighborhood Hits	65	Target Neighborhood Hits	165	Shared Neighborhood Hits	30
SwissProt Accessions	Q9ERZ6, Q3TPB0, Q3UP57, Q6PCM0	Gene names	Fign
Domain Architecture	No domain graphic available
Description	Fidgetin.

FIGN_HUMAN
NC score	0.071870 (rank : 71)	θ value	θ > 10 (rank : 75)
Query Neighborhood Hits	65	Target Neighborhood Hits	176	Shared Neighborhood Hits	30
SwissProt Accessions	Q5HY92, Q9H6M5, Q9NVZ9	Gene names	FIGN
Domain Architecture	No domain graphic available
Description	Fidgetin.

HELZ_HUMAN
NC score	0.066064 (rank : 72)	θ value	4.03905 (rank : 46)
Query Neighborhood Hits	65	Target Neighborhood Hits	198	Shared Neighborhood Hits	13
SwissProt Accessions	P42694	Gene names	HELZ, KIAA0054
Domain Architecture	No domain graphic available
Description	Probable helicase with zinc-finger domain (EC 3.6.1.-).

MOV10_MOUSE
NC score	0.064332 (rank : 73)	θ value	8.99809 (rank : 64)
Query Neighborhood Hits	65	Target Neighborhood Hits	39	Shared Neighborhood Hits	16
SwissProt Accessions	P23249, Q9DC64	Gene names	Mov10, Gb110
Domain Architecture
Description	Putative helicase MOV-10 (EC 3.6.1.-) (Moloney leukemia virus 10 protein).

MOV10_HUMAN
NC score	0.063854 (rank : 74)	θ value	5.27518 (rank : 53)
Query Neighborhood Hits	65	Target Neighborhood Hits	46	Shared Neighborhood Hits	16
SwissProt Accessions	Q9HCE1, Q8TEF0, Q9BSY3, Q9BUJ9	Gene names	MOV10, KIAA1631
Domain Architecture
Description	Putative helicase MOV-10 (EC 3.6.1.-) (Moloney leukemia virus 10 protein).

CLPX_MOUSE
NC score	0.058325 (rank : 75)	θ value	θ > 10 (rank : 74)
Query Neighborhood Hits	65	Target Neighborhood Hits	73	Shared Neighborhood Hits	30
SwissProt Accessions	Q9JHS4, Q9WVD1	Gene names	Clpx
Domain Architecture
Description	ATP-dependent Clp protease ATP-binding subunit ClpX-like, mitochondrial precursor.

CLPX_HUMAN
NC score	0.058216 (rank : 76)	θ value	θ > 10 (rank : 73)
Query Neighborhood Hits	65	Target Neighborhood Hits	72	Shared Neighborhood Hits	30
SwissProt Accessions	O76031, Q9H4D9	Gene names	CLPX
Domain Architecture
Description	ATP-dependent Clp protease ATP-binding subunit ClpX-like, mitochondrial precursor.

CDC6_MOUSE
NC score	0.052337 (rank : 77)	θ value	θ > 10 (rank : 72)
Query Neighborhood Hits	65	Target Neighborhood Hits	32	Shared Neighborhood Hits	8
SwissProt Accessions	O89033, Q3TMD0, Q8C3S5, Q9CZT0	Gene names	Cdc6
Domain Architecture	No domain graphic available
Description	Cell division control protein 6 homolog (CDC6-related protein) (p62(cdc6)).

RENT1_MOUSE
NC score	0.049064 (rank : 78)	θ value	4.03905 (rank : 48)
Query Neighborhood Hits	65	Target Neighborhood Hits	54	Shared Neighborhood Hits	13
SwissProt Accessions	Q9EPU0, Q99PR4	Gene names	Upf1, Rent1
Domain Architecture
Description	Regulator of nonsense transcripts 1 (EC 3.6.1.-) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up- frameshift suppressor 1 homolog) (mUpf1).

RENT1_HUMAN
NC score	0.049050 (rank : 79)	θ value	4.03905 (rank : 47)
Query Neighborhood Hits	65	Target Neighborhood Hits	51	Shared Neighborhood Hits	13
SwissProt Accessions	Q92900, O00239, O43343, Q86Z25, Q92842	Gene names	UPF1, KIAA0221, RENT1
Domain Architecture
Description	Regulator of nonsense transcripts 1 (EC 3.6.1.-) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up- frameshift suppressor 1 homolog) (hUpf1).

KIF22_HUMAN
NC score	0.017321 (rank : 80)	θ value	1.38821 (rank : 29)
Query Neighborhood Hits	65	Target Neighborhood Hits	110	Shared Neighborhood Hits	4
SwissProt Accessions	Q14807, O94814, Q9BT46	Gene names	KIF22, KID, KNSL4
Domain Architecture
Description	Kinesin-like protein KIF22 (Kinesin-like DNA-binding protein) (Kinesin-like protein 4).

SFRS5_MOUSE
NC score	0.013908 (rank : 81)	θ value	5.27518 (rank : 58)
Query Neighborhood Hits	65	Target Neighborhood Hits	175	Shared Neighborhood Hits	3
SwissProt Accessions	O35326	Gene names	Sfrs5, Hrs
Domain Architecture
Description	Splicing factor, arginine/serine-rich 5 (Pre-mRNA-splicing factor SRP40) (Delayed-early protein HRS).

STX5_MOUSE
NC score	0.012136 (rank : 82)	θ value	8.99809 (rank : 65)
Query Neighborhood Hits	65	Target Neighborhood Hits	69	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K1E0, Q3TM79, Q99J28, Q9JKP2	Gene names	Stx5, Stx5a
Domain Architecture
Description	Syntaxin-5.

CASP1_HUMAN
NC score	0.010216 (rank : 83)	θ value	8.99809 (rank : 61)
Query Neighborhood Hits	65	Target Neighborhood Hits	41	Shared Neighborhood Hits	3
SwissProt Accessions	P29466, Q9UCN3	Gene names	CASP1, IL1BC, IL1BCE
Domain Architecture
Description	Caspase-1 precursor (EC 3.4.22.36) (CASP-1) (Interleukin-1 beta convertase) (IL-1BC) (IL-1 beta-converting enzyme) (ICE) (Interleukin- 1 beta-converting enzyme) (p45) [Contains: Caspase-1 p20 subunit; Caspase-1 p10 subunit].

CF188_HUMAN
NC score	0.009748 (rank : 84)	θ value	8.99809 (rank : 62)
Query Neighborhood Hits	65	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N5C1	Gene names	C6orf188
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf188.

KI18A_HUMAN
NC score	0.007469 (rank : 85)	θ value	5.27518 (rank : 51)
Query Neighborhood Hits	65	Target Neighborhood Hits	168	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NI77, Q86VS5, Q9H0F3	Gene names	KIF18A
Domain Architecture	No domain graphic available
Description	Kinesin family member 18A.

CF060_HUMAN
NC score	0.003823 (rank : 86)	θ value	3.0926 (rank : 43)
Query Neighborhood Hits	65	Target Neighborhood Hits	1270	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NB25, Q96GY8, Q9H851	Gene names	C6orf60
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf60.

CHD5_HUMAN
NC score	0.002573 (rank : 87)	θ value	8.99809 (rank : 63)
Query Neighborhood Hits	65	Target Neighborhood Hits	349	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

REST_MOUSE
NC score	0.001310 (rank : 88)	θ value	5.27518 (rank : 57)
Query Neighborhood Hits	65	Target Neighborhood Hits	1506	Shared Neighborhood Hits	6
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

BCL6B_HUMAN
NC score	-0.001793 (rank : 89)	θ value	8.99809 (rank : 60)
Query Neighborhood Hits	65	Target Neighborhood Hits	855	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N143, Q6PCB4	Gene names	BCL6B, BAZF, ZNF62
Domain Architecture	No domain graphic available
Description	B-cell CLL/lymphoma 6 member B protein (Bcl6-associated zinc finger protein) (Zinc finger protein 62).