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Network neighborhood for query Sequence : M10L1_MOUSE

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M10L1_MOUSE
SwissProt Accessions	Q99MV5, Q7TPA9, Q8C3W0, Q924C2	Gene names	Mov10l1, Champ
Domain Architecture
Description	Putative helicase Mov10l1 (EC 3.6.1.-) (Moloney leukemia virus 10-like protein 1) (MOV10-like 1) (Cardiac helicase activated by MEF2 protein) (Cardiac-specific RNA helicase).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

M10L1_HUMAN
θ value	0 (rank : 1)	NC score	0.980439 (rank : 2)
Query Neighborhood Hits	59	Target Neighborhood Hits	36	Shared Neighborhood Hits	24
SwissProt Accessions	Q9BXT6, Q5TGD5, Q8NBD4, Q9NXW3, Q9UFB3, Q9UGX9	Gene names	MOV10L1
Domain Architecture
Description	Putative helicase Mov10l1 (EC 3.6.1.-) (Moloney leukemia virus 10-like protein 1) (MOV10-like 1).

M10L1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	59	Target Neighborhood Hits	59	Shared Neighborhood Hits	59
SwissProt Accessions	Q99MV5, Q7TPA9, Q8C3W0, Q924C2	Gene names	Mov10l1, Champ
Domain Architecture
Description	Putative helicase Mov10l1 (EC 3.6.1.-) (Moloney leukemia virus 10-like protein 1) (MOV10-like 1) (Cardiac helicase activated by MEF2 protein) (Cardiac-specific RNA helicase).

MOV10_HUMAN
θ value	7.14227e-106 (rank : 3)	NC score	0.901160 (rank : 3)
Query Neighborhood Hits	59	Target Neighborhood Hits	46	Shared Neighborhood Hits	23
SwissProt Accessions	Q9HCE1, Q8TEF0, Q9BSY3, Q9BUJ9	Gene names	MOV10, KIAA1631
Domain Architecture
Description	Putative helicase MOV-10 (EC 3.6.1.-) (Moloney leukemia virus 10 protein).

MOV10_MOUSE
θ value	1.34698e-104 (rank : 4)	NC score	0.899228 (rank : 4)
Query Neighborhood Hits	59	Target Neighborhood Hits	39	Shared Neighborhood Hits	23
SwissProt Accessions	P23249, Q9DC64	Gene names	Mov10, Gb110
Domain Architecture
Description	Putative helicase MOV-10 (EC 3.6.1.-) (Moloney leukemia virus 10 protein).

HELZ_HUMAN
θ value	4.40402e-47 (rank : 5)	NC score	0.774453 (rank : 5)
Query Neighborhood Hits	59	Target Neighborhood Hits	198	Shared Neighborhood Hits	23
SwissProt Accessions	P42694	Gene names	HELZ, KIAA0054
Domain Architecture	No domain graphic available
Description	Probable helicase with zinc-finger domain (EC 3.6.1.-).

CX048_HUMAN
θ value	4.86918e-46 (rank : 6)	NC score	0.633322 (rank : 11)
Query Neighborhood Hits	59	Target Neighborhood Hits	9	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WUE5, Q9NWY8	Gene names	CXorf48
Domain Architecture	No domain graphic available
Description	Protein CXorf48 (Tumor antigen BJ-HCC-20).

RENT1_HUMAN
θ value	2.42216e-37 (rank : 7)	NC score	0.762172 (rank : 7)
Query Neighborhood Hits	59	Target Neighborhood Hits	51	Shared Neighborhood Hits	19
SwissProt Accessions	Q92900, O00239, O43343, Q86Z25, Q92842	Gene names	UPF1, KIAA0221, RENT1
Domain Architecture
Description	Regulator of nonsense transcripts 1 (EC 3.6.1.-) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up- frameshift suppressor 1 homolog) (hUpf1).

RENT1_MOUSE
θ value	2.42216e-37 (rank : 8)	NC score	0.762390 (rank : 6)
Query Neighborhood Hits	59	Target Neighborhood Hits	54	Shared Neighborhood Hits	19
SwissProt Accessions	Q9EPU0, Q99PR4	Gene names	Upf1, Rent1
Domain Architecture
Description	Regulator of nonsense transcripts 1 (EC 3.6.1.-) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up- frameshift suppressor 1 homolog) (mUpf1).

PR285_HUMAN
θ value	9.8567e-31 (rank : 9)	NC score	0.724986 (rank : 8)
Query Neighborhood Hits	59	Target Neighborhood Hits	63	Shared Neighborhood Hits	19
SwissProt Accessions	Q9BYK8, Q3C2G2, Q4VXQ1, Q8TEF3, Q96ND3, Q9C094	Gene names	PRIC285, KIAA1769
Domain Architecture
Description	Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein (EC 3.6.1.-) (ATP-dependent helicase PRIC285) (PPAR-alpha- interacting complex protein 285) (PPAR-gamma DBD-interacting protein 1) (PDIP1).

SMBP2_HUMAN
θ value	8.63488e-27 (rank : 10)	NC score	0.708699 (rank : 9)
Query Neighborhood Hits	59	Target Neighborhood Hits	107	Shared Neighborhood Hits	19
SwissProt Accessions	P38935, Q00443, Q14177	Gene names	IGHMBP2, SMBP2, SMUBP2
Domain Architecture
Description	DNA-binding protein SMUBP-2 (EC 3.6.1.-) (ATP-dependent helicase IGHMBP2) (Immunoglobulin mu-binding protein 2) (SMUBP-2) (Glial factor 1) (GF-1).

SETX_HUMAN
θ value	4.43474e-23 (rank : 11)	NC score	0.631763 (rank : 12)
Query Neighborhood Hits	59	Target Neighborhood Hits	368	Shared Neighborhood Hits	23
SwissProt Accessions	Q7Z333, O75120, Q3KQX4, Q68DW5, Q6AZD7, Q7Z3J6, Q8WX33, Q9H9D1, Q9NVP9	Gene names	SETX, ALS4, KIAA0625, SCAR1
Domain Architecture
Description	Probable helicase senataxin (EC 3.6.1.-) (SEN1 homolog).

SMBP2_MOUSE
θ value	2.69047e-20 (rank : 12)	NC score	0.695654 (rank : 10)
Query Neighborhood Hits	59	Target Neighborhood Hits	104	Shared Neighborhood Hits	20
SwissProt Accessions	P40694	Gene names	Ighmbp2, Smbp-2, Smbp2
Domain Architecture
Description	DNA-binding protein SMUBP-2 (EC 3.6.1.-) (ATP-dependent helicase IGHMBP2) (Immunoglobulin mu-binding protein 2) (SMUBP-2) (Cardiac transcription factor 1) (CATF1).

ZNFX1_HUMAN
θ value	7.34386e-10 (rank : 13)	NC score	0.408459 (rank : 13)
Query Neighborhood Hits	59	Target Neighborhood Hits	308	Shared Neighborhood Hits	18
SwissProt Accessions	Q9P2E3, Q9BQM7, Q9BQM8, Q9H8C1, Q9H9S2, Q9NUM1, Q9NWW1	Gene names	ZNFX1, KIAA1404
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

ZNFX1_MOUSE
θ value	1.38499e-08 (rank : 14)	NC score	0.407450 (rank : 14)
Query Neighborhood Hits	59	Target Neighborhood Hits	407	Shared Neighborhood Hits	19
SwissProt Accessions	Q8R151, Q3U016, Q3UD71, Q3UEZ0	Gene names	ZNFX1
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

AQR_HUMAN
θ value	4.1701e-05 (rank : 15)	NC score	0.371955 (rank : 16)
Query Neighborhood Hits	59	Target Neighborhood Hits	88	Shared Neighborhood Hits	15
SwissProt Accessions	O60306, Q2YDX9, Q6IRU8, Q6PIC8	Gene names	AQR, KIAA0560
Domain Architecture	No domain graphic available
Description	Intron-binding protein aquarius (Intron-binding protein of 160 kDa) (IBP160).

AQR_MOUSE
θ value	4.1701e-05 (rank : 16)	NC score	0.374327 (rank : 15)
Query Neighborhood Hits	59	Target Neighborhood Hits	62	Shared Neighborhood Hits	15
SwissProt Accessions	Q8CFQ3, P97871, Q3U9N1, Q3ULE8, Q80TX8	Gene names	Aqr, Kiaa0560
Domain Architecture	No domain graphic available
Description	Intron-binding protein aquarius.

NIPBL_HUMAN
θ value	0.0961366 (rank : 17)	NC score	0.031028 (rank : 45)
Query Neighborhood Hits	59	Target Neighborhood Hits	1311	Shared Neighborhood Hits	14
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

RFC4_MOUSE
θ value	0.125558 (rank : 18)	NC score	0.084022 (rank : 18)
Query Neighborhood Hits	59	Target Neighborhood Hits	65	Shared Neighborhood Hits	12
SwissProt Accessions	Q99J62	Gene names	Rfc4
Domain Architecture	No domain graphic available
Description	Replication factor C subunit 4.

NEST_HUMAN
θ value	0.163984 (rank : 19)	NC score	0.017233 (rank : 52)
Query Neighborhood Hits	59	Target Neighborhood Hits	1305	Shared Neighborhood Hits	11
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

CYLC1_HUMAN
θ value	0.21417 (rank : 20)	NC score	0.048392 (rank : 41)
Query Neighborhood Hits	59	Target Neighborhood Hits	408	Shared Neighborhood Hits	9
SwissProt Accessions	P35663, Q5JQQ9	Gene names	CYLC1, CYL, CYL1
Domain Architecture	No domain graphic available
Description	Cylicin-1 (Cylicin I) (Multiple-band polypeptide I).

SRRM2_HUMAN
θ value	0.21417 (rank : 21)	NC score	0.032568 (rank : 44)
Query Neighborhood Hits	59	Target Neighborhood Hits	1296	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

ENK5_HUMAN
θ value	0.365318 (rank : 22)	NC score	0.066096 (rank : 25)
Query Neighborhood Hits	59	Target Neighborhood Hits	43	Shared Neighborhood Hits	14
SwissProt Accessions	Q902F9	Gene names
Domain Architecture
Description	HERV-K_19p13.11 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (HERV-K113 envelope protein) (EnvK5 protein) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENK4_HUMAN
θ value	0.47712 (rank : 23)	NC score	0.065756 (rank : 26)
Query Neighborhood Hits	59	Target Neighborhood Hits	50	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UKH3	Gene names
Domain Architecture
Description	HERV-K_6q14.1 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (HERV-K109 envelope protein) (HERV-K(C6) envelope protein) (EnvK4 protein) [Contains: Surface protein (SU); Transmembrane protein (TM)].

RFC5_MOUSE
θ value	0.47712 (rank : 24)	NC score	0.085602 (rank : 17)
Query Neighborhood Hits	59	Target Neighborhood Hits	58	Shared Neighborhood Hits	14
SwissProt Accessions	Q9D0F6	Gene names	Rfc5
Domain Architecture
Description	Replication factor C subunit 5 (Replication factor C 36 kDa subunit) (RF-C 36 kDa subunit) (RFC36) (Activator 1 36 kDa subunit) (A1 36 kDa subunit).

TRI66_MOUSE
θ value	0.47712 (rank : 25)	NC score	0.022632 (rank : 49)
Query Neighborhood Hits	59	Target Neighborhood Hits	491	Shared Neighborhood Hits	5
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

ENK11_HUMAN
θ value	0.62314 (rank : 26)	NC score	0.069950 (rank : 21)
Query Neighborhood Hits	59	Target Neighborhood Hits	27	Shared Neighborhood Hits	14
SwissProt Accessions	P61566	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_22q11.21 provirus ancestral Env polyprotein (Envelope polyprotein) (HERV-K101 envelope protein) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENK12_HUMAN
θ value	0.62314 (rank : 27)	NC score	0.069870 (rank : 22)
Query Neighborhood Hits	59	Target Neighborhood Hits	27	Shared Neighborhood Hits	14
SwissProt Accessions	P61567	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q22 provirus ancestral Env polyprotein (Envelope polyprotein) (HERV-K102 envelope protein) (HERV-K(III) envelope protein) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENK17_HUMAN
θ value	0.62314 (rank : 28)	NC score	0.065137 (rank : 32)
Query Neighborhood Hits	59	Target Neighborhood Hits	44	Shared Neighborhood Hits	14
SwissProt Accessions	P61570	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_11q22.1 provirus ancestral Env polyprotein precursor (Envelope polyprotein) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENK2_HUMAN
θ value	0.62314 (rank : 29)	NC score	0.065322 (rank : 28)
Query Neighborhood Hits	59	Target Neighborhood Hits	44	Shared Neighborhood Hits	14
SwissProt Accessions	Q69384, Q8TD93, Q9UBU4, Q9YNA5, Q9YNA9	Gene names	ERVK6
Domain Architecture
Description	HERV-K_7p22.1 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (HERV-K(HML-2.HOM) envelope protein) (HERV-K108 envelope protein) (HERV-K(C7) envelope protein) (EnvK2 protein) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENK3_HUMAN
θ value	0.62314 (rank : 30)	NC score	0.065278 (rank : 30)
Query Neighborhood Hits	59	Target Neighborhood Hits	44	Shared Neighborhood Hits	14
SwissProt Accessions	O71037, Q69386, Q9YNA7	Gene names
Domain Architecture
Description	HERV-K_19q12 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (HERV-K(C19) envelope protein) (EnvK3 protein) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENK6_HUMAN
θ value	0.62314 (rank : 31)	NC score	0.065280 (rank : 29)
Query Neighborhood Hits	59	Target Neighborhood Hits	50	Shared Neighborhood Hits	14
SwissProt Accessions	Q902F8	Gene names
Domain Architecture
Description	HERV-K_8p23.1 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (HERV-K115 envelope protein) (EnvK6 protein) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENK8_HUMAN
θ value	0.62314 (rank : 32)	NC score	0.069254 (rank : 23)
Query Neighborhood Hits	59	Target Neighborhood Hits	27	Shared Neighborhood Hits	14
SwissProt Accessions	Q9HDB8	Gene names	ERVK5
Domain Architecture	No domain graphic available
Description	HERV-K_3q12.3 provirus ancestral Env polyprotein (Envelope polyprotein) (HERV-K(II) envelope protein) [Includes: Truncated surface protein (SU)].

NCA11_MOUSE
θ value	0.62314 (rank : 33)	NC score	0.012385 (rank : 60)
Query Neighborhood Hits	59	Target Neighborhood Hits	661	Shared Neighborhood Hits	5
SwissProt Accessions	P13595, Q61949	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 180 kDa isoform precursor (N-CAM 180) (NCAM-180).

NCA12_MOUSE
θ value	0.62314 (rank : 34)	NC score	0.012786 (rank : 58)
Query Neighborhood Hits	59	Target Neighborhood Hits	399	Shared Neighborhood Hits	4
SwissProt Accessions	P13594, Q61950	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 120 kDa isoform precursor (N-CAM 120) (NCAM-120).

POK12_HUMAN
θ value	0.62314 (rank : 35)	NC score	0.053564 (rank : 40)
Query Neighborhood Hits	59	Target Neighborhood Hits	50	Shared Neighborhood Hits	16
SwissProt Accessions	P63135	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q22 provirus ancestral Pol protein (HERV-K102 Pol protein) (HERV-K(III) Pol protein) [Includes: Reverse transcriptase (RT) (EC 2.7.7.49); Ribonuclease H (EC 3.1.26.4) (RNase H); Integrase (IN)].

DYHC_HUMAN
θ value	0.813845 (rank : 36)	NC score	0.042225 (rank : 43)
Query Neighborhood Hits	59	Target Neighborhood Hits	733	Shared Neighborhood Hits	14
SwissProt Accessions	Q14204, Q6DKQ7, Q8WU28, Q92814, Q9Y4G5	Gene names	DYNC1H1, DNCH1, DNECL, KIAA0325
Domain Architecture	No domain graphic available
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

DYHC_MOUSE
θ value	0.813845 (rank : 37)	NC score	0.042261 (rank : 42)
Query Neighborhood Hits	59	Target Neighborhood Hits	729	Shared Neighborhood Hits	14
SwissProt Accessions	Q9JHU4	Gene names	Dync1h1, Dnch1, Dnchc1
Domain Architecture
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

RBBP6_HUMAN
θ value	1.06291 (rank : 38)	NC score	0.024163 (rank : 46)
Query Neighborhood Hits	59	Target Neighborhood Hits	1135	Shared Neighborhood Hits	11
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

ENK1_HUMAN
θ value	1.38821 (rank : 39)	NC score	0.064436 (rank : 33)
Query Neighborhood Hits	59	Target Neighborhood Hits	44	Shared Neighborhood Hits	14
SwissProt Accessions	P61565	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_12q14.1 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (EnvK1 protein) [Contains: Surface protein (SU); Transmembrane protein (TM)].

PRS8_HUMAN
θ value	1.38821 (rank : 40)	NC score	0.024025 (rank : 47)
Query Neighborhood Hits	59	Target Neighborhood Hits	117	Shared Neighborhood Hits	7
SwissProt Accessions	P62195, O35051, O43208, P47210, P52915, P52916	Gene names	PSMC5, SUG1
Domain Architecture
Description	26S protease regulatory subunit 8 (Proteasome 26S subunit ATPase 5) (Proteasome subunit p45) (p45/SUG) (Thyroid hormone receptor- interacting protein 1) (TRIP1).

PRS8_MOUSE
θ value	1.38821 (rank : 41)	NC score	0.024025 (rank : 48)
Query Neighborhood Hits	59	Target Neighborhood Hits	117	Shared Neighborhood Hits	7
SwissProt Accessions	P62196, O35051, P47210, P52915, P52916, Q3UL51, Q9CWN5	Gene names	Psmc5, Sug1
Domain Architecture
Description	26S protease regulatory subunit 8 (Proteasome 26S subunit ATPase 5) (Proteasome subunit p45) (p45/SUG) (mSUG1).

RFC4_HUMAN
θ value	1.38821 (rank : 42)	NC score	0.078025 (rank : 20)
Query Neighborhood Hits	59	Target Neighborhood Hits	64	Shared Neighborhood Hits	13
SwissProt Accessions	P35249, Q6FHX7	Gene names	RFC4
Domain Architecture
Description	Replication factor C subunit 4 (Replication factor C 37 kDa subunit) (RF-C 37 kDa subunit) (RFC37) (Activator 1 37 kDa subunit) (A1 37 kDa subunit).

RFC5_HUMAN
θ value	1.38821 (rank : 43)	NC score	0.079017 (rank : 19)
Query Neighborhood Hits	59	Target Neighborhood Hits	60	Shared Neighborhood Hits	13
SwissProt Accessions	P40937	Gene names	RFC5
Domain Architecture
Description	Replication factor C subunit 5 (Replication factor C 36 kDa subunit) (RF-C 36 kDa subunit) (RFC36) (Activator 1 36 kDa subunit) (A1 36 kDa subunit).

ENK10_HUMAN
θ value	2.36792 (rank : 44)	NC score	0.067769 (rank : 24)
Query Neighborhood Hits	59	Target Neighborhood Hits	26	Shared Neighborhood Hits	14
SwissProt Accessions	P10267, Q14273	Gene names
Domain Architecture
Description	HERV-K_5q33.3 provirus ancestral Env polyprotein (Envelope polyprotein) (HERV-K10 envelope protein) (HERV-K107 envelope protein) [Contains: Surface protein (SU); Transmembrane protein (TM)].

MPP4_HUMAN
θ value	3.0926 (rank : 45)	NC score	0.017391 (rank : 51)
Query Neighborhood Hits	59	Target Neighborhood Hits	205	Shared Neighborhood Hits	4
SwissProt Accessions	Q96JB8, Q6ZNH6, Q96Q43, Q96Q44	Gene names	MPP4, ALS2CR5, DLG6
Domain Architecture
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 5 protein).

NKTR_HUMAN
θ value	3.0926 (rank : 46)	NC score	0.013287 (rank : 56)
Query Neighborhood Hits	59	Target Neighborhood Hits	658	Shared Neighborhood Hits	10
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

PDL1_HUMAN
θ value	3.0926 (rank : 47)	NC score	0.015707 (rank : 53)
Query Neighborhood Hits	59	Target Neighborhood Hits	195	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NZQ7, Q66RK1, Q6WEX4, Q9NUZ5	Gene names	CD274, B7H1, PDCD1L1, PDCD1LG1, PDL1
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 1 precursor (Programmed death ligand 1) (PD-L1) (PDCD1 ligand 1) (B7 homolog 1) (B7-H1) (CD274 antigen).

RBBP6_MOUSE
θ value	5.27518 (rank : 48)	NC score	0.021908 (rank : 50)
Query Neighborhood Hits	59	Target Neighborhood Hits	1014	Shared Neighborhood Hits	12
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

AFF1_HUMAN
θ value	6.88961 (rank : 49)	NC score	0.013208 (rank : 57)
Query Neighborhood Hits	59	Target Neighborhood Hits	506	Shared Neighborhood Hits	10
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

ANK1_HUMAN
θ value	6.88961 (rank : 50)	NC score	0.002708 (rank : 65)
Query Neighborhood Hits	59	Target Neighborhood Hits	416	Shared Neighborhood Hits	4
SwissProt Accessions	P16157, O43400, Q13768, Q59FP2, Q8N604, Q99407	Gene names	ANK1, ANK
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin) (Ankyrin-R).

ENK7_HUMAN
θ value	6.88961 (rank : 51)	NC score	0.065718 (rank : 27)
Query Neighborhood Hits	59	Target Neighborhood Hits	27	Shared Neighborhood Hits	14
SwissProt Accessions	O42043, O95280, Q96PI3, Q96PI6, Q9QC06	Gene names
Domain Architecture
Description	HERV-K_1q23.3 provirus ancestral Env polyprotein (Envelope polyprotein) (HERV-K18 envelope protein) (HERV-K110 envelope protein) (IDDMK1,2 22 envelope protein) (HERV-K(C1a) envelope protein) (HERV- K18 superantigen) (IDDMK1,2 22 superantigen) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ANK1_MOUSE
θ value	8.99809 (rank : 52)	NC score	0.002251 (rank : 66)
Query Neighborhood Hits	59	Target Neighborhood Hits	430	Shared Neighborhood Hits	3
SwissProt Accessions	Q02357, P70440, P97446, P97941, Q3TZ35, Q3UH42, Q3UHP2, Q3UYY7, Q61302, Q61303, Q78E45	Gene names	Ank1, Ank-1
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin).

DEK_MOUSE
θ value	8.99809 (rank : 53)	NC score	0.014017 (rank : 55)
Query Neighborhood Hits	59	Target Neighborhood Hits	280	Shared Neighborhood Hits	6
SwissProt Accessions	Q7TNV0, Q80VC5, Q8BZV6	Gene names	Dek
Domain Architecture	No domain graphic available
Description	Protein DEK.

FHOD1_HUMAN
θ value	8.99809 (rank : 54)	NC score	0.007494 (rank : 62)
Query Neighborhood Hits	59	Target Neighborhood Hits	184	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y613, Q59F76, Q6Y1F2, Q76MS8, Q8N521	Gene names	FHOD1, FHOS
Domain Architecture
Description	FH1/FH2 domain-containing protein (Formin homolog overexpressed in spleen) (FHOS) (Formin homology 2 domain-containing protein 1).

JARD2_MOUSE
θ value	8.99809 (rank : 55)	NC score	0.009770 (rank : 61)
Query Neighborhood Hits	59	Target Neighborhood Hits	169	Shared Neighborhood Hits	9
SwissProt Accessions	Q62315, Q99LD1	Gene names	Jarid2, Jmj
Domain Architecture
Description	Jumonji protein (Jumonji/ARID domain-containing protein 2).

K1967_MOUSE
θ value	8.99809 (rank : 56)	NC score	0.015341 (rank : 54)
Query Neighborhood Hits	59	Target Neighborhood Hits	136	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VDP4, Q6PIB1, Q8BWR5, Q8C0F0, Q8R3G6	Gene names
Domain Architecture	No domain graphic available
Description	Protein KIAA1967 homolog.

MPP4_MOUSE
θ value	8.99809 (rank : 57)	NC score	0.012748 (rank : 59)
Query Neighborhood Hits	59	Target Neighborhood Hits	188	Shared Neighborhood Hits	4
SwissProt Accessions	Q6P7F1, Q8BTT3, Q8BXM5, Q920P7, Q920P8	Gene names	Mpp4, Dlg6
Domain Architecture	No domain graphic available
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (MDLG6).

PKHA6_HUMAN
θ value	8.99809 (rank : 58)	NC score	0.005990 (rank : 63)
Query Neighborhood Hits	59	Target Neighborhood Hits	556	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

SYNE1_HUMAN
θ value	8.99809 (rank : 59)	NC score	0.002886 (rank : 64)
Query Neighborhood Hits	59	Target Neighborhood Hits	1484	Shared Neighborhood Hits	10
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

ENK13_HUMAN
θ value	θ > 10 (rank : 60)	NC score	0.056282 (rank : 36)
Query Neighborhood Hits	59	Target Neighborhood Hits	23	Shared Neighborhood Hits	13
SwissProt Accessions	P61568	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1p13.3 provirus ancestral Env polyprotein (Envelope polyprotein) [Includes: Truncated surface protein (SU)].

ENK14_HUMAN
θ value	θ > 10 (rank : 61)	NC score	0.065207 (rank : 31)
Query Neighborhood Hits	59	Target Neighborhood Hits	19	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NX77	Gene names
Domain Architecture
Description	HERV-K_16p3.3 provirus ancestral Env polyprotein (Envelope polyprotein) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENK15_HUMAN
θ value	θ > 10 (rank : 62)	NC score	0.059082 (rank : 34)
Query Neighborhood Hits	59	Target Neighborhood Hits	20	Shared Neighborhood Hits	13
SwissProt Accessions	Q9HDC0	Gene names	ERVK4
Domain Architecture	No domain graphic available
Description	HERV-K_3q21.2 provirus ancestral Env polyprotein (Envelope polyprotein) (HERV-K(I) envelope protein) [Includes: Truncated surface protein (SU)].

ENK16_HUMAN
θ value	θ > 10 (rank : 63)	NC score	0.054331 (rank : 38)
Query Neighborhood Hits	59	Target Neighborhood Hits	37	Shared Neighborhood Hits	13
SwissProt Accessions	P61569	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_10p14 provirus ancestral Env polyprotein precursor (Envelope polyprotein) [Includes: Truncated surface protein (SU)].

ENK19_HUMAN
θ value	θ > 10 (rank : 64)	NC score	0.055103 (rank : 37)
Query Neighborhood Hits	59	Target Neighborhood Hits	37	Shared Neighborhood Hits	13
SwissProt Accessions	Q6ZVY0	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_4p16.1 provirus ancestral Env polyprotein precursor (Envelope polyprotein) [Includes: Truncated surface protein (SU)].

ENK9_HUMAN
θ value	θ > 10 (rank : 65)	NC score	0.053738 (rank : 39)
Query Neighborhood Hits	59	Target Neighborhood Hits	39	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UKH7	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_5q13.3 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (HERV-K104 envelope protein) [Includes: Truncated surface protein (SU)].

RRP44_HUMAN
θ value	θ > 10 (rank : 66)	NC score	0.057553 (rank : 35)
Query Neighborhood Hits	59	Target Neighborhood Hits	35	Shared Neighborhood Hits	1
SwissProt Accessions	Q9Y2L1, Q5W0P7, Q5W0P8, Q658Z7, Q7Z481, Q8WWI2, Q9UG36	Gene names	DIS3, KIAA1008, RRP44
Domain Architecture
Description	Exosome complex exonuclease RRP44 (EC 3.1.13.-) (Ribosomal RNA- processing protein 44) (DIS3 protein homolog).

Hits sorted by NC score

M10L1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	59	Target Neighborhood Hits	59	Shared Neighborhood Hits	59
SwissProt Accessions	Q99MV5, Q7TPA9, Q8C3W0, Q924C2	Gene names	Mov10l1, Champ
Domain Architecture
Description	Putative helicase Mov10l1 (EC 3.6.1.-) (Moloney leukemia virus 10-like protein 1) (MOV10-like 1) (Cardiac helicase activated by MEF2 protein) (Cardiac-specific RNA helicase).

M10L1_HUMAN
NC score	0.980439 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	59	Target Neighborhood Hits	36	Shared Neighborhood Hits	24
SwissProt Accessions	Q9BXT6, Q5TGD5, Q8NBD4, Q9NXW3, Q9UFB3, Q9UGX9	Gene names	MOV10L1
Domain Architecture
Description	Putative helicase Mov10l1 (EC 3.6.1.-) (Moloney leukemia virus 10-like protein 1) (MOV10-like 1).

MOV10_HUMAN
NC score	0.901160 (rank : 3)	θ value	7.14227e-106 (rank : 3)
Query Neighborhood Hits	59	Target Neighborhood Hits	46	Shared Neighborhood Hits	23
SwissProt Accessions	Q9HCE1, Q8TEF0, Q9BSY3, Q9BUJ9	Gene names	MOV10, KIAA1631
Domain Architecture
Description	Putative helicase MOV-10 (EC 3.6.1.-) (Moloney leukemia virus 10 protein).

MOV10_MOUSE
NC score	0.899228 (rank : 4)	θ value	1.34698e-104 (rank : 4)
Query Neighborhood Hits	59	Target Neighborhood Hits	39	Shared Neighborhood Hits	23
SwissProt Accessions	P23249, Q9DC64	Gene names	Mov10, Gb110
Domain Architecture
Description	Putative helicase MOV-10 (EC 3.6.1.-) (Moloney leukemia virus 10 protein).

HELZ_HUMAN
NC score	0.774453 (rank : 5)	θ value	4.40402e-47 (rank : 5)
Query Neighborhood Hits	59	Target Neighborhood Hits	198	Shared Neighborhood Hits	23
SwissProt Accessions	P42694	Gene names	HELZ, KIAA0054
Domain Architecture	No domain graphic available
Description	Probable helicase with zinc-finger domain (EC 3.6.1.-).

RENT1_MOUSE
NC score	0.762390 (rank : 6)	θ value	2.42216e-37 (rank : 8)
Query Neighborhood Hits	59	Target Neighborhood Hits	54	Shared Neighborhood Hits	19
SwissProt Accessions	Q9EPU0, Q99PR4	Gene names	Upf1, Rent1
Domain Architecture
Description	Regulator of nonsense transcripts 1 (EC 3.6.1.-) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up- frameshift suppressor 1 homolog) (mUpf1).

RENT1_HUMAN
NC score	0.762172 (rank : 7)	θ value	2.42216e-37 (rank : 7)
Query Neighborhood Hits	59	Target Neighborhood Hits	51	Shared Neighborhood Hits	19
SwissProt Accessions	Q92900, O00239, O43343, Q86Z25, Q92842	Gene names	UPF1, KIAA0221, RENT1
Domain Architecture
Description	Regulator of nonsense transcripts 1 (EC 3.6.1.-) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up- frameshift suppressor 1 homolog) (hUpf1).

PR285_HUMAN
NC score	0.724986 (rank : 8)	θ value	9.8567e-31 (rank : 9)
Query Neighborhood Hits	59	Target Neighborhood Hits	63	Shared Neighborhood Hits	19
SwissProt Accessions	Q9BYK8, Q3C2G2, Q4VXQ1, Q8TEF3, Q96ND3, Q9C094	Gene names	PRIC285, KIAA1769
Domain Architecture
Description	Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein (EC 3.6.1.-) (ATP-dependent helicase PRIC285) (PPAR-alpha- interacting complex protein 285) (PPAR-gamma DBD-interacting protein 1) (PDIP1).

SMBP2_HUMAN
NC score	0.708699 (rank : 9)	θ value	8.63488e-27 (rank : 10)
Query Neighborhood Hits	59	Target Neighborhood Hits	107	Shared Neighborhood Hits	19
SwissProt Accessions	P38935, Q00443, Q14177	Gene names	IGHMBP2, SMBP2, SMUBP2
Domain Architecture
Description	DNA-binding protein SMUBP-2 (EC 3.6.1.-) (ATP-dependent helicase IGHMBP2) (Immunoglobulin mu-binding protein 2) (SMUBP-2) (Glial factor 1) (GF-1).

SMBP2_MOUSE
NC score	0.695654 (rank : 10)	θ value	2.69047e-20 (rank : 12)
Query Neighborhood Hits	59	Target Neighborhood Hits	104	Shared Neighborhood Hits	20
SwissProt Accessions	P40694	Gene names	Ighmbp2, Smbp-2, Smbp2
Domain Architecture
Description	DNA-binding protein SMUBP-2 (EC 3.6.1.-) (ATP-dependent helicase IGHMBP2) (Immunoglobulin mu-binding protein 2) (SMUBP-2) (Cardiac transcription factor 1) (CATF1).

CX048_HUMAN
NC score	0.633322 (rank : 11)	θ value	4.86918e-46 (rank : 6)
Query Neighborhood Hits	59	Target Neighborhood Hits	9	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WUE5, Q9NWY8	Gene names	CXorf48
Domain Architecture	No domain graphic available
Description	Protein CXorf48 (Tumor antigen BJ-HCC-20).

SETX_HUMAN
NC score	0.631763 (rank : 12)	θ value	4.43474e-23 (rank : 11)
Query Neighborhood Hits	59	Target Neighborhood Hits	368	Shared Neighborhood Hits	23
SwissProt Accessions	Q7Z333, O75120, Q3KQX4, Q68DW5, Q6AZD7, Q7Z3J6, Q8WX33, Q9H9D1, Q9NVP9	Gene names	SETX, ALS4, KIAA0625, SCAR1
Domain Architecture
Description	Probable helicase senataxin (EC 3.6.1.-) (SEN1 homolog).

ZNFX1_HUMAN
NC score	0.408459 (rank : 13)	θ value	7.34386e-10 (rank : 13)
Query Neighborhood Hits	59	Target Neighborhood Hits	308	Shared Neighborhood Hits	18
SwissProt Accessions	Q9P2E3, Q9BQM7, Q9BQM8, Q9H8C1, Q9H9S2, Q9NUM1, Q9NWW1	Gene names	ZNFX1, KIAA1404
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

ZNFX1_MOUSE
NC score	0.407450 (rank : 14)	θ value	1.38499e-08 (rank : 14)
Query Neighborhood Hits	59	Target Neighborhood Hits	407	Shared Neighborhood Hits	19
SwissProt Accessions	Q8R151, Q3U016, Q3UD71, Q3UEZ0	Gene names	ZNFX1
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

AQR_MOUSE
NC score	0.374327 (rank : 15)	θ value	4.1701e-05 (rank : 16)
Query Neighborhood Hits	59	Target Neighborhood Hits	62	Shared Neighborhood Hits	15
SwissProt Accessions	Q8CFQ3, P97871, Q3U9N1, Q3ULE8, Q80TX8	Gene names	Aqr, Kiaa0560
Domain Architecture	No domain graphic available
Description	Intron-binding protein aquarius.

AQR_HUMAN
NC score	0.371955 (rank : 16)	θ value	4.1701e-05 (rank : 15)
Query Neighborhood Hits	59	Target Neighborhood Hits	88	Shared Neighborhood Hits	15
SwissProt Accessions	O60306, Q2YDX9, Q6IRU8, Q6PIC8	Gene names	AQR, KIAA0560
Domain Architecture	No domain graphic available
Description	Intron-binding protein aquarius (Intron-binding protein of 160 kDa) (IBP160).

RFC5_MOUSE
NC score	0.085602 (rank : 17)	θ value	0.47712 (rank : 24)
Query Neighborhood Hits	59	Target Neighborhood Hits	58	Shared Neighborhood Hits	14
SwissProt Accessions	Q9D0F6	Gene names	Rfc5
Domain Architecture
Description	Replication factor C subunit 5 (Replication factor C 36 kDa subunit) (RF-C 36 kDa subunit) (RFC36) (Activator 1 36 kDa subunit) (A1 36 kDa subunit).

RFC4_MOUSE
NC score	0.084022 (rank : 18)	θ value	0.125558 (rank : 18)
Query Neighborhood Hits	59	Target Neighborhood Hits	65	Shared Neighborhood Hits	12
SwissProt Accessions	Q99J62	Gene names	Rfc4
Domain Architecture	No domain graphic available
Description	Replication factor C subunit 4.

RFC5_HUMAN
NC score	0.079017 (rank : 19)	θ value	1.38821 (rank : 43)
Query Neighborhood Hits	59	Target Neighborhood Hits	60	Shared Neighborhood Hits	13
SwissProt Accessions	P40937	Gene names	RFC5
Domain Architecture
Description	Replication factor C subunit 5 (Replication factor C 36 kDa subunit) (RF-C 36 kDa subunit) (RFC36) (Activator 1 36 kDa subunit) (A1 36 kDa subunit).

RFC4_HUMAN
NC score	0.078025 (rank : 20)	θ value	1.38821 (rank : 42)
Query Neighborhood Hits	59	Target Neighborhood Hits	64	Shared Neighborhood Hits	13
SwissProt Accessions	P35249, Q6FHX7	Gene names	RFC4
Domain Architecture
Description	Replication factor C subunit 4 (Replication factor C 37 kDa subunit) (RF-C 37 kDa subunit) (RFC37) (Activator 1 37 kDa subunit) (A1 37 kDa subunit).

ENK11_HUMAN
NC score	0.069950 (rank : 21)	θ value	0.62314 (rank : 26)
Query Neighborhood Hits	59	Target Neighborhood Hits	27	Shared Neighborhood Hits	14
SwissProt Accessions	P61566	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_22q11.21 provirus ancestral Env polyprotein (Envelope polyprotein) (HERV-K101 envelope protein) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENK12_HUMAN
NC score	0.069870 (rank : 22)	θ value	0.62314 (rank : 27)
Query Neighborhood Hits	59	Target Neighborhood Hits	27	Shared Neighborhood Hits	14
SwissProt Accessions	P61567	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q22 provirus ancestral Env polyprotein (Envelope polyprotein) (HERV-K102 envelope protein) (HERV-K(III) envelope protein) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENK8_HUMAN
NC score	0.069254 (rank : 23)	θ value	0.62314 (rank : 32)
Query Neighborhood Hits	59	Target Neighborhood Hits	27	Shared Neighborhood Hits	14
SwissProt Accessions	Q9HDB8	Gene names	ERVK5
Domain Architecture	No domain graphic available
Description	HERV-K_3q12.3 provirus ancestral Env polyprotein (Envelope polyprotein) (HERV-K(II) envelope protein) [Includes: Truncated surface protein (SU)].

ENK10_HUMAN
NC score	0.067769 (rank : 24)	θ value	2.36792 (rank : 44)
Query Neighborhood Hits	59	Target Neighborhood Hits	26	Shared Neighborhood Hits	14
SwissProt Accessions	P10267, Q14273	Gene names
Domain Architecture
Description	HERV-K_5q33.3 provirus ancestral Env polyprotein (Envelope polyprotein) (HERV-K10 envelope protein) (HERV-K107 envelope protein) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENK5_HUMAN
NC score	0.066096 (rank : 25)	θ value	0.365318 (rank : 22)
Query Neighborhood Hits	59	Target Neighborhood Hits	43	Shared Neighborhood Hits	14
SwissProt Accessions	Q902F9	Gene names
Domain Architecture
Description	HERV-K_19p13.11 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (HERV-K113 envelope protein) (EnvK5 protein) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENK4_HUMAN
NC score	0.065756 (rank : 26)	θ value	0.47712 (rank : 23)
Query Neighborhood Hits	59	Target Neighborhood Hits	50	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UKH3	Gene names
Domain Architecture
Description	HERV-K_6q14.1 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (HERV-K109 envelope protein) (HERV-K(C6) envelope protein) (EnvK4 protein) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENK7_HUMAN
NC score	0.065718 (rank : 27)	θ value	6.88961 (rank : 51)
Query Neighborhood Hits	59	Target Neighborhood Hits	27	Shared Neighborhood Hits	14
SwissProt Accessions	O42043, O95280, Q96PI3, Q96PI6, Q9QC06	Gene names
Domain Architecture
Description	HERV-K_1q23.3 provirus ancestral Env polyprotein (Envelope polyprotein) (HERV-K18 envelope protein) (HERV-K110 envelope protein) (IDDMK1,2 22 envelope protein) (HERV-K(C1a) envelope protein) (HERV- K18 superantigen) (IDDMK1,2 22 superantigen) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENK2_HUMAN
NC score	0.065322 (rank : 28)	θ value	0.62314 (rank : 29)
Query Neighborhood Hits	59	Target Neighborhood Hits	44	Shared Neighborhood Hits	14
SwissProt Accessions	Q69384, Q8TD93, Q9UBU4, Q9YNA5, Q9YNA9	Gene names	ERVK6
Domain Architecture
Description	HERV-K_7p22.1 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (HERV-K(HML-2.HOM) envelope protein) (HERV-K108 envelope protein) (HERV-K(C7) envelope protein) (EnvK2 protein) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENK6_HUMAN
NC score	0.065280 (rank : 29)	θ value	0.62314 (rank : 31)
Query Neighborhood Hits	59	Target Neighborhood Hits	50	Shared Neighborhood Hits	14
SwissProt Accessions	Q902F8	Gene names
Domain Architecture
Description	HERV-K_8p23.1 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (HERV-K115 envelope protein) (EnvK6 protein) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENK3_HUMAN
NC score	0.065278 (rank : 30)	θ value	0.62314 (rank : 30)
Query Neighborhood Hits	59	Target Neighborhood Hits	44	Shared Neighborhood Hits	14
SwissProt Accessions	O71037, Q69386, Q9YNA7	Gene names
Domain Architecture
Description	HERV-K_19q12 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (HERV-K(C19) envelope protein) (EnvK3 protein) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENK14_HUMAN
NC score	0.065207 (rank : 31)	θ value	θ > 10 (rank : 61)
Query Neighborhood Hits	59	Target Neighborhood Hits	19	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NX77	Gene names
Domain Architecture
Description	HERV-K_16p3.3 provirus ancestral Env polyprotein (Envelope polyprotein) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENK17_HUMAN
NC score	0.065137 (rank : 32)	θ value	0.62314 (rank : 28)
Query Neighborhood Hits	59	Target Neighborhood Hits	44	Shared Neighborhood Hits	14
SwissProt Accessions	P61570	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_11q22.1 provirus ancestral Env polyprotein precursor (Envelope polyprotein) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENK1_HUMAN
NC score	0.064436 (rank : 33)	θ value	1.38821 (rank : 39)
Query Neighborhood Hits	59	Target Neighborhood Hits	44	Shared Neighborhood Hits	14
SwissProt Accessions	P61565	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_12q14.1 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (EnvK1 protein) [Contains: Surface protein (SU); Transmembrane protein (TM)].

ENK15_HUMAN
NC score	0.059082 (rank : 34)	θ value	θ > 10 (rank : 62)
Query Neighborhood Hits	59	Target Neighborhood Hits	20	Shared Neighborhood Hits	13
SwissProt Accessions	Q9HDC0	Gene names	ERVK4
Domain Architecture	No domain graphic available
Description	HERV-K_3q21.2 provirus ancestral Env polyprotein (Envelope polyprotein) (HERV-K(I) envelope protein) [Includes: Truncated surface protein (SU)].

RRP44_HUMAN
NC score	0.057553 (rank : 35)	θ value	θ > 10 (rank : 66)
Query Neighborhood Hits	59	Target Neighborhood Hits	35	Shared Neighborhood Hits	1
SwissProt Accessions	Q9Y2L1, Q5W0P7, Q5W0P8, Q658Z7, Q7Z481, Q8WWI2, Q9UG36	Gene names	DIS3, KIAA1008, RRP44
Domain Architecture
Description	Exosome complex exonuclease RRP44 (EC 3.1.13.-) (Ribosomal RNA- processing protein 44) (DIS3 protein homolog).

ENK13_HUMAN
NC score	0.056282 (rank : 36)	θ value	θ > 10 (rank : 60)
Query Neighborhood Hits	59	Target Neighborhood Hits	23	Shared Neighborhood Hits	13
SwissProt Accessions	P61568	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1p13.3 provirus ancestral Env polyprotein (Envelope polyprotein) [Includes: Truncated surface protein (SU)].

ENK19_HUMAN
NC score	0.055103 (rank : 37)	θ value	θ > 10 (rank : 64)
Query Neighborhood Hits	59	Target Neighborhood Hits	37	Shared Neighborhood Hits	13
SwissProt Accessions	Q6ZVY0	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_4p16.1 provirus ancestral Env polyprotein precursor (Envelope polyprotein) [Includes: Truncated surface protein (SU)].

ENK16_HUMAN
NC score	0.054331 (rank : 38)	θ value	θ > 10 (rank : 63)
Query Neighborhood Hits	59	Target Neighborhood Hits	37	Shared Neighborhood Hits	13
SwissProt Accessions	P61569	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_10p14 provirus ancestral Env polyprotein precursor (Envelope polyprotein) [Includes: Truncated surface protein (SU)].

ENK9_HUMAN
NC score	0.053738 (rank : 39)	θ value	θ > 10 (rank : 65)
Query Neighborhood Hits	59	Target Neighborhood Hits	39	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UKH7	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_5q13.3 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (HERV-K104 envelope protein) [Includes: Truncated surface protein (SU)].

POK12_HUMAN
NC score	0.053564 (rank : 40)	θ value	0.62314 (rank : 35)
Query Neighborhood Hits	59	Target Neighborhood Hits	50	Shared Neighborhood Hits	16
SwissProt Accessions	P63135	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q22 provirus ancestral Pol protein (HERV-K102 Pol protein) (HERV-K(III) Pol protein) [Includes: Reverse transcriptase (RT) (EC 2.7.7.49); Ribonuclease H (EC 3.1.26.4) (RNase H); Integrase (IN)].

CYLC1_HUMAN
NC score	0.048392 (rank : 41)	θ value	0.21417 (rank : 20)
Query Neighborhood Hits	59	Target Neighborhood Hits	408	Shared Neighborhood Hits	9
SwissProt Accessions	P35663, Q5JQQ9	Gene names	CYLC1, CYL, CYL1
Domain Architecture	No domain graphic available
Description	Cylicin-1 (Cylicin I) (Multiple-band polypeptide I).

DYHC_MOUSE
NC score	0.042261 (rank : 42)	θ value	0.813845 (rank : 37)
Query Neighborhood Hits	59	Target Neighborhood Hits	729	Shared Neighborhood Hits	14
SwissProt Accessions	Q9JHU4	Gene names	Dync1h1, Dnch1, Dnchc1
Domain Architecture
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

DYHC_HUMAN
NC score	0.042225 (rank : 43)	θ value	0.813845 (rank : 36)
Query Neighborhood Hits	59	Target Neighborhood Hits	733	Shared Neighborhood Hits	14
SwissProt Accessions	Q14204, Q6DKQ7, Q8WU28, Q92814, Q9Y4G5	Gene names	DYNC1H1, DNCH1, DNECL, KIAA0325
Domain Architecture	No domain graphic available
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

SRRM2_HUMAN
NC score	0.032568 (rank : 44)	θ value	0.21417 (rank : 21)
Query Neighborhood Hits	59	Target Neighborhood Hits	1296	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

NIPBL_HUMAN
NC score	0.031028 (rank : 45)	θ value	0.0961366 (rank : 17)
Query Neighborhood Hits	59	Target Neighborhood Hits	1311	Shared Neighborhood Hits	14
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

RBBP6_HUMAN
NC score	0.024163 (rank : 46)	θ value	1.06291 (rank : 38)
Query Neighborhood Hits	59	Target Neighborhood Hits	1135	Shared Neighborhood Hits	11
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

PRS8_HUMAN
NC score	0.024025 (rank : 47)	θ value	1.38821 (rank : 40)
Query Neighborhood Hits	59	Target Neighborhood Hits	117	Shared Neighborhood Hits	7
SwissProt Accessions	P62195, O35051, O43208, P47210, P52915, P52916	Gene names	PSMC5, SUG1
Domain Architecture
Description	26S protease regulatory subunit 8 (Proteasome 26S subunit ATPase 5) (Proteasome subunit p45) (p45/SUG) (Thyroid hormone receptor- interacting protein 1) (TRIP1).

PRS8_MOUSE
NC score	0.024025 (rank : 48)	θ value	1.38821 (rank : 41)
Query Neighborhood Hits	59	Target Neighborhood Hits	117	Shared Neighborhood Hits	7
SwissProt Accessions	P62196, O35051, P47210, P52915, P52916, Q3UL51, Q9CWN5	Gene names	Psmc5, Sug1
Domain Architecture
Description	26S protease regulatory subunit 8 (Proteasome 26S subunit ATPase 5) (Proteasome subunit p45) (p45/SUG) (mSUG1).

TRI66_MOUSE
NC score	0.022632 (rank : 49)	θ value	0.47712 (rank : 25)
Query Neighborhood Hits	59	Target Neighborhood Hits	491	Shared Neighborhood Hits	5
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

RBBP6_MOUSE
NC score	0.021908 (rank : 50)	θ value	5.27518 (rank : 48)
Query Neighborhood Hits	59	Target Neighborhood Hits	1014	Shared Neighborhood Hits	12
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

MPP4_HUMAN
NC score	0.017391 (rank : 51)	θ value	3.0926 (rank : 45)
Query Neighborhood Hits	59	Target Neighborhood Hits	205	Shared Neighborhood Hits	4
SwissProt Accessions	Q96JB8, Q6ZNH6, Q96Q43, Q96Q44	Gene names	MPP4, ALS2CR5, DLG6
Domain Architecture
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 5 protein).

NEST_HUMAN
NC score	0.017233 (rank : 52)	θ value	0.163984 (rank : 19)
Query Neighborhood Hits	59	Target Neighborhood Hits	1305	Shared Neighborhood Hits	11
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

PDL1_HUMAN
NC score	0.015707 (rank : 53)	θ value	3.0926 (rank : 47)
Query Neighborhood Hits	59	Target Neighborhood Hits	195	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NZQ7, Q66RK1, Q6WEX4, Q9NUZ5	Gene names	CD274, B7H1, PDCD1L1, PDCD1LG1, PDL1
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 1 precursor (Programmed death ligand 1) (PD-L1) (PDCD1 ligand 1) (B7 homolog 1) (B7-H1) (CD274 antigen).

K1967_MOUSE
NC score	0.015341 (rank : 54)	θ value	8.99809 (rank : 56)
Query Neighborhood Hits	59	Target Neighborhood Hits	136	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VDP4, Q6PIB1, Q8BWR5, Q8C0F0, Q8R3G6	Gene names
Domain Architecture	No domain graphic available
Description	Protein KIAA1967 homolog.

DEK_MOUSE
NC score	0.014017 (rank : 55)	θ value	8.99809 (rank : 53)
Query Neighborhood Hits	59	Target Neighborhood Hits	280	Shared Neighborhood Hits	6
SwissProt Accessions	Q7TNV0, Q80VC5, Q8BZV6	Gene names	Dek
Domain Architecture	No domain graphic available
Description	Protein DEK.

NKTR_HUMAN
NC score	0.013287 (rank : 56)	θ value	3.0926 (rank : 46)
Query Neighborhood Hits	59	Target Neighborhood Hits	658	Shared Neighborhood Hits	10
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

AFF1_HUMAN
NC score	0.013208 (rank : 57)	θ value	6.88961 (rank : 49)
Query Neighborhood Hits	59	Target Neighborhood Hits	506	Shared Neighborhood Hits	10
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

NCA12_MOUSE
NC score	0.012786 (rank : 58)	θ value	0.62314 (rank : 34)
Query Neighborhood Hits	59	Target Neighborhood Hits	399	Shared Neighborhood Hits	4
SwissProt Accessions	P13594, Q61950	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 120 kDa isoform precursor (N-CAM 120) (NCAM-120).

MPP4_MOUSE
NC score	0.012748 (rank : 59)	θ value	8.99809 (rank : 57)
Query Neighborhood Hits	59	Target Neighborhood Hits	188	Shared Neighborhood Hits	4
SwissProt Accessions	Q6P7F1, Q8BTT3, Q8BXM5, Q920P7, Q920P8	Gene names	Mpp4, Dlg6
Domain Architecture	No domain graphic available
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (MDLG6).

NCA11_MOUSE
NC score	0.012385 (rank : 60)	θ value	0.62314 (rank : 33)
Query Neighborhood Hits	59	Target Neighborhood Hits	661	Shared Neighborhood Hits	5
SwissProt Accessions	P13595, Q61949	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 180 kDa isoform precursor (N-CAM 180) (NCAM-180).

JARD2_MOUSE
NC score	0.009770 (rank : 61)	θ value	8.99809 (rank : 55)
Query Neighborhood Hits	59	Target Neighborhood Hits	169	Shared Neighborhood Hits	9
SwissProt Accessions	Q62315, Q99LD1	Gene names	Jarid2, Jmj
Domain Architecture
Description	Jumonji protein (Jumonji/ARID domain-containing protein 2).

FHOD1_HUMAN
NC score	0.007494 (rank : 62)	θ value	8.99809 (rank : 54)
Query Neighborhood Hits	59	Target Neighborhood Hits	184	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y613, Q59F76, Q6Y1F2, Q76MS8, Q8N521	Gene names	FHOD1, FHOS
Domain Architecture
Description	FH1/FH2 domain-containing protein (Formin homolog overexpressed in spleen) (FHOS) (Formin homology 2 domain-containing protein 1).

PKHA6_HUMAN
NC score	0.005990 (rank : 63)	θ value	8.99809 (rank : 58)
Query Neighborhood Hits	59	Target Neighborhood Hits	556	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

SYNE1_HUMAN
NC score	0.002886 (rank : 64)	θ value	8.99809 (rank : 59)
Query Neighborhood Hits	59	Target Neighborhood Hits	1484	Shared Neighborhood Hits	10
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

ANK1_HUMAN
NC score	0.002708 (rank : 65)	θ value	6.88961 (rank : 50)
Query Neighborhood Hits	59	Target Neighborhood Hits	416	Shared Neighborhood Hits	4
SwissProt Accessions	P16157, O43400, Q13768, Q59FP2, Q8N604, Q99407	Gene names	ANK1, ANK
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin) (Ankyrin-R).

ANK1_MOUSE
NC score	0.002251 (rank : 66)	θ value	8.99809 (rank : 52)
Query Neighborhood Hits	59	Target Neighborhood Hits	430	Shared Neighborhood Hits	3
SwissProt Accessions	Q02357, P70440, P97446, P97941, Q3TZ35, Q3UH42, Q3UHP2, Q3UYY7, Q61302, Q61303, Q78E45	Gene names	Ank1, Ank-1
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin).