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Network neighborhood for query Sequence : AQR_HUMAN

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AQR_HUMAN
SwissProt Accessions	O60306, Q2YDX9, Q6IRU8, Q6PIC8	Gene names	AQR, KIAA0560
Domain Architecture	No domain graphic available
Description	Intron-binding protein aquarius (Intron-binding protein of 160 kDa) (IBP160).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

AQR_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	88	Target Neighborhood Hits	88	Shared Neighborhood Hits	88
SwissProt Accessions	O60306, Q2YDX9, Q6IRU8, Q6PIC8	Gene names	AQR, KIAA0560
Domain Architecture	No domain graphic available
Description	Intron-binding protein aquarius (Intron-binding protein of 160 kDa) (IBP160).

AQR_MOUSE
θ value	0 (rank : 2)	NC score	0.991481 (rank : 2)
Query Neighborhood Hits	88	Target Neighborhood Hits	62	Shared Neighborhood Hits	46
SwissProt Accessions	Q8CFQ3, P97871, Q3U9N1, Q3ULE8, Q80TX8	Gene names	Aqr, Kiaa0560
Domain Architecture	No domain graphic available
Description	Intron-binding protein aquarius.

ZNFX1_MOUSE
θ value	1.73987e-27 (rank : 3)	NC score	0.516609 (rank : 6)
Query Neighborhood Hits	88	Target Neighborhood Hits	407	Shared Neighborhood Hits	21
SwissProt Accessions	Q8R151, Q3U016, Q3UD71, Q3UEZ0	Gene names	ZNFX1
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

ZNFX1_HUMAN
θ value	2.27234e-27 (rank : 4)	NC score	0.520763 (rank : 5)
Query Neighborhood Hits	88	Target Neighborhood Hits	308	Shared Neighborhood Hits	27
SwissProt Accessions	Q9P2E3, Q9BQM7, Q9BQM8, Q9H8C1, Q9H9S2, Q9NUM1, Q9NWW1	Gene names	ZNFX1, KIAA1404
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

RENT1_HUMAN
θ value	2.97466e-19 (rank : 5)	NC score	0.570851 (rank : 3)
Query Neighborhood Hits	88	Target Neighborhood Hits	51	Shared Neighborhood Hits	17
SwissProt Accessions	Q92900, O00239, O43343, Q86Z25, Q92842	Gene names	UPF1, KIAA0221, RENT1
Domain Architecture
Description	Regulator of nonsense transcripts 1 (EC 3.6.1.-) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up- frameshift suppressor 1 homolog) (hUpf1).

RENT1_MOUSE
θ value	2.97466e-19 (rank : 6)	NC score	0.570678 (rank : 4)
Query Neighborhood Hits	88	Target Neighborhood Hits	54	Shared Neighborhood Hits	17
SwissProt Accessions	Q9EPU0, Q99PR4	Gene names	Upf1, Rent1
Domain Architecture
Description	Regulator of nonsense transcripts 1 (EC 3.6.1.-) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up- frameshift suppressor 1 homolog) (mUpf1).

SETX_HUMAN
θ value	8.95645e-16 (rank : 7)	NC score	0.508597 (rank : 7)
Query Neighborhood Hits	88	Target Neighborhood Hits	368	Shared Neighborhood Hits	22
SwissProt Accessions	Q7Z333, O75120, Q3KQX4, Q68DW5, Q6AZD7, Q7Z3J6, Q8WX33, Q9H9D1, Q9NVP9	Gene names	SETX, ALS4, KIAA0625, SCAR1
Domain Architecture
Description	Probable helicase senataxin (EC 3.6.1.-) (SEN1 homolog).

SMBP2_MOUSE
θ value	5.62301e-10 (rank : 8)	NC score	0.483230 (rank : 8)
Query Neighborhood Hits	88	Target Neighborhood Hits	104	Shared Neighborhood Hits	17
SwissProt Accessions	P40694	Gene names	Ighmbp2, Smbp-2, Smbp2
Domain Architecture
Description	DNA-binding protein SMUBP-2 (EC 3.6.1.-) (ATP-dependent helicase IGHMBP2) (Immunoglobulin mu-binding protein 2) (SMUBP-2) (Cardiac transcription factor 1) (CATF1).

SMBP2_HUMAN
θ value	2.13673e-09 (rank : 9)	NC score	0.478201 (rank : 9)
Query Neighborhood Hits	88	Target Neighborhood Hits	107	Shared Neighborhood Hits	17
SwissProt Accessions	P38935, Q00443, Q14177	Gene names	IGHMBP2, SMBP2, SMUBP2
Domain Architecture
Description	DNA-binding protein SMUBP-2 (EC 3.6.1.-) (ATP-dependent helicase IGHMBP2) (Immunoglobulin mu-binding protein 2) (SMUBP-2) (Glial factor 1) (GF-1).

PR285_HUMAN
θ value	1.06045e-08 (rank : 10)	NC score	0.441107 (rank : 10)
Query Neighborhood Hits	88	Target Neighborhood Hits	63	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BYK8, Q3C2G2, Q4VXQ1, Q8TEF3, Q96ND3, Q9C094	Gene names	PRIC285, KIAA1769
Domain Architecture
Description	Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein (EC 3.6.1.-) (ATP-dependent helicase PRIC285) (PPAR-alpha- interacting complex protein 285) (PPAR-gamma DBD-interacting protein 1) (PDIP1).

M10L1_HUMAN
θ value	2.88788e-06 (rank : 11)	NC score	0.386528 (rank : 11)
Query Neighborhood Hits	88	Target Neighborhood Hits	36	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BXT6, Q5TGD5, Q8NBD4, Q9NXW3, Q9UFB3, Q9UGX9	Gene names	MOV10L1
Domain Architecture
Description	Putative helicase Mov10l1 (EC 3.6.1.-) (Moloney leukemia virus 10-like protein 1) (MOV10-like 1).

M10L1_MOUSE
θ value	4.1701e-05 (rank : 12)	NC score	0.371955 (rank : 12)
Query Neighborhood Hits	88	Target Neighborhood Hits	59	Shared Neighborhood Hits	15
SwissProt Accessions	Q99MV5, Q7TPA9, Q8C3W0, Q924C2	Gene names	Mov10l1, Champ
Domain Architecture
Description	Putative helicase Mov10l1 (EC 3.6.1.-) (Moloney leukemia virus 10-like protein 1) (MOV10-like 1) (Cardiac helicase activated by MEF2 protein) (Cardiac-specific RNA helicase).

HELZ_HUMAN
θ value	0.00390308 (rank : 13)	NC score	0.337026 (rank : 15)
Query Neighborhood Hits	88	Target Neighborhood Hits	198	Shared Neighborhood Hits	16
SwissProt Accessions	P42694	Gene names	HELZ, KIAA0054
Domain Architecture	No domain graphic available
Description	Probable helicase with zinc-finger domain (EC 3.6.1.-).

MOV10_HUMAN
θ value	0.00509761 (rank : 14)	NC score	0.346807 (rank : 13)
Query Neighborhood Hits	88	Target Neighborhood Hits	46	Shared Neighborhood Hits	17
SwissProt Accessions	Q9HCE1, Q8TEF0, Q9BSY3, Q9BUJ9	Gene names	MOV10, KIAA1631
Domain Architecture
Description	Putative helicase MOV-10 (EC 3.6.1.-) (Moloney leukemia virus 10 protein).

MOV10_MOUSE
θ value	0.0252991 (rank : 15)	NC score	0.339734 (rank : 14)
Query Neighborhood Hits	88	Target Neighborhood Hits	39	Shared Neighborhood Hits	17
SwissProt Accessions	P23249, Q9DC64	Gene names	Mov10, Gb110
Domain Architecture
Description	Putative helicase MOV-10 (EC 3.6.1.-) (Moloney leukemia virus 10 protein).

MUC7_HUMAN
θ value	0.0330416 (rank : 16)	NC score	0.059239 (rank : 38)
Query Neighborhood Hits	88	Target Neighborhood Hits	538	Shared Neighborhood Hits	16
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

RA51D_MOUSE
θ value	0.0563607 (rank : 17)	NC score	0.110258 (rank : 16)
Query Neighborhood Hits	88	Target Neighborhood Hits	18	Shared Neighborhood Hits	4
SwissProt Accessions	O55230	Gene names	Rad51l3, R51h3, Rad51d
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD51 homolog 4 (R51H3) (RAD51-like protein 3).

CCD27_HUMAN
θ value	0.0961366 (rank : 18)	NC score	0.047850 (rank : 52)
Query Neighborhood Hits	88	Target Neighborhood Hits	594	Shared Neighborhood Hits	12
SwissProt Accessions	Q2M243, Q5TBV3, Q96M50	Gene names	CCDC27
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 27.

MUC5B_HUMAN
θ value	0.0961366 (rank : 19)	NC score	0.052896 (rank : 45)
Query Neighborhood Hits	88	Target Neighborhood Hits	1020	Shared Neighborhood Hits	24
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

PRG4_HUMAN
θ value	0.125558 (rank : 20)	NC score	0.041876 (rank : 59)
Query Neighborhood Hits	88	Target Neighborhood Hits	764	Shared Neighborhood Hits	20
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

RA51D_HUMAN
θ value	0.21417 (rank : 21)	NC score	0.096362 (rank : 18)
Query Neighborhood Hits	88	Target Neighborhood Hits	18	Shared Neighborhood Hits	4
SwissProt Accessions	O75771, O43537, O60355, O75196, O75847, O75848, O76073, O76085, O94908, Q9UFU5	Gene names	RAD51L3, RAD51D
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD51 homolog 4 (R51H3) (RAD51-like protein 3) (TRAD).

MUC1_MOUSE
θ value	0.279714 (rank : 22)	NC score	0.062997 (rank : 33)
Query Neighborhood Hits	88	Target Neighborhood Hits	388	Shared Neighborhood Hits	18
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

SELPL_MOUSE
θ value	0.279714 (rank : 23)	NC score	0.061523 (rank : 35)
Query Neighborhood Hits	88	Target Neighborhood Hits	588	Shared Neighborhood Hits	21
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

FANCM_HUMAN
θ value	0.365318 (rank : 24)	NC score	0.067107 (rank : 29)
Query Neighborhood Hits	88	Target Neighborhood Hits	210	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IYD8, Q3YFH9, Q8N9X6, Q9HCH6	Gene names	FANCM, KIAA1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog).

FANCM_MOUSE
θ value	0.365318 (rank : 25)	NC score	0.064866 (rank : 31)
Query Neighborhood Hits	88	Target Neighborhood Hits	177	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BGE5, Q69ZF5, Q8BKB7, Q8BUA8	Gene names	Fancm, Kiaa1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein homolog (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM).

GLI2_HUMAN
θ value	0.62314 (rank : 26)	NC score	0.007316 (rank : 102)
Query Neighborhood Hits	88	Target Neighborhood Hits	971	Shared Neighborhood Hits	6
SwissProt Accessions	P10070, O60252, O60253, O60254, O60255, Q15590, Q15591	Gene names	GLI2, THP
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI2 (Tax helper protein).

NVL_HUMAN
θ value	0.62314 (rank : 27)	NC score	0.044220 (rank : 56)
Query Neighborhood Hits	88	Target Neighborhood Hits	112	Shared Neighborhood Hits	14
SwissProt Accessions	O15381, Q96EM7	Gene names	NVL
Domain Architecture
Description	Nuclear valosin-containing protein-like (Nuclear VCP-like protein) (NVLp).

NVL_MOUSE
θ value	0.62314 (rank : 28)	NC score	0.043833 (rank : 58)
Query Neighborhood Hits	88	Target Neighborhood Hits	110	Shared Neighborhood Hits	13
SwissProt Accessions	Q9DBY8, Q3USC4, Q8BW27, Q8K2B5	Gene names	Nvl
Domain Architecture
Description	Nuclear valosin-containing protein-like (Nuclear VCP-like protein) (NVLp).

TCRG1_MOUSE
θ value	0.62314 (rank : 29)	NC score	0.031589 (rank : 71)
Query Neighborhood Hits	88	Target Neighborhood Hits	947	Shared Neighborhood Hits	16
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

M3K13_HUMAN
θ value	0.813845 (rank : 30)	NC score	0.005246 (rank : 113)
Query Neighborhood Hits	88	Target Neighborhood Hits	911	Shared Neighborhood Hits	8
SwissProt Accessions	O43283	Gene names	MAP3K13, LZK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 13 (EC 2.7.11.25) (Mixed lineage kinase) (MLK) (Leucine zipper-bearing kinase).

MAP2_MOUSE
θ value	0.813845 (rank : 31)	NC score	0.033254 (rank : 68)
Query Neighborhood Hits	88	Target Neighborhood Hits	342	Shared Neighborhood Hits	13
SwissProt Accessions	P20357	Gene names	Map2, Mtap2
Domain Architecture
Description	Microtubule-associated protein 2 (MAP 2).

MUC1_HUMAN
θ value	0.813845 (rank : 32)	NC score	0.031548 (rank : 72)
Query Neighborhood Hits	88	Target Neighborhood Hits	975	Shared Neighborhood Hits	22
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

NAL10_MOUSE
θ value	0.813845 (rank : 33)	NC score	0.028872 (rank : 76)
Query Neighborhood Hits	88	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CCN1	Gene names	Nalp10, Pynod
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 10.

DDX58_MOUSE
θ value	1.06291 (rank : 34)	NC score	0.051619 (rank : 48)
Query Neighborhood Hits	88	Target Neighborhood Hits	99	Shared Neighborhood Hits	7
SwissProt Accessions	Q6Q899, Q8C320, Q8C5I3, Q8C7T2	Gene names	Ddx58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

NU214_HUMAN
θ value	1.06291 (rank : 35)	NC score	0.045340 (rank : 54)
Query Neighborhood Hits	88	Target Neighborhood Hits	657	Shared Neighborhood Hits	19
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

RD23B_MOUSE
θ value	1.06291 (rank : 36)	NC score	0.034252 (rank : 67)
Query Neighborhood Hits	88	Target Neighborhood Hits	189	Shared Neighborhood Hits	10
SwissProt Accessions	P54728	Gene names	Rad23b, Mhr23b
Domain Architecture
Description	UV excision repair protein RAD23 homolog B (mHR23B) (XP-C repair- complementing complex 58 kDa protein) (p58).

ZAN_MOUSE
θ value	1.06291 (rank : 37)	NC score	0.029959 (rank : 74)
Query Neighborhood Hits	88	Target Neighborhood Hits	808	Shared Neighborhood Hits	15
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

KLC1_MOUSE
θ value	1.38821 (rank : 38)	NC score	0.024677 (rank : 83)
Query Neighborhood Hits	88	Target Neighborhood Hits	357	Shared Neighborhood Hits	10
SwissProt Accessions	O88447	Gene names	Kns2, Klc1
Domain Architecture	No domain graphic available
Description	Kinesin light chain 1 (KLC 1).

MUC2_HUMAN
θ value	1.38821 (rank : 39)	NC score	0.036866 (rank : 63)
Query Neighborhood Hits	88	Target Neighborhood Hits	906	Shared Neighborhood Hits	16
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

ZFY27_HUMAN
θ value	1.38821 (rank : 40)	NC score	0.028416 (rank : 78)
Query Neighborhood Hits	88	Target Neighborhood Hits	64	Shared Neighborhood Hits	2
SwissProt Accessions	Q5T4F4, Q5T4F1, Q5T4F2, Q5T4F3, Q8N1K0, Q8N6D6, Q8NCA0, Q8NDE4, Q96M08	Gene names	ZFYVE27
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 27.

GP1BA_HUMAN
θ value	1.81305 (rank : 41)	NC score	0.014966 (rank : 88)
Query Neighborhood Hits	88	Target Neighborhood Hits	407	Shared Neighborhood Hits	9
SwissProt Accessions	P07359, Q14441, Q16469, Q8N1F3, Q8NG39, Q9HDC7, Q9UEK1, Q9UQS4	Gene names	GP1BA
Domain Architecture
Description	Platelet glycoprotein Ib alpha chain precursor (Glycoprotein Ibalpha) (GP-Ib alpha) (GPIbA) (GPIb-alpha) (Antigen CD42b-alpha) (CD42b antigen) [Contains: Glycocalicin].

MDC1_MOUSE
θ value	1.81305 (rank : 42)	NC score	0.041133 (rank : 60)
Query Neighborhood Hits	88	Target Neighborhood Hits	998	Shared Neighborhood Hits	26
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

MRCKB_HUMAN
θ value	1.81305 (rank : 43)	NC score	0.007204 (rank : 103)
Query Neighborhood Hits	88	Target Neighborhood Hits	2239	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

NACAM_MOUSE
θ value	1.81305 (rank : 44)	NC score	0.034708 (rank : 65)
Query Neighborhood Hits	88	Target Neighborhood Hits	1866	Shared Neighborhood Hits	28
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

PEX6_HUMAN
θ value	1.81305 (rank : 45)	NC score	0.044821 (rank : 55)
Query Neighborhood Hits	88	Target Neighborhood Hits	99	Shared Neighborhood Hits	19
SwissProt Accessions	Q13608, Q8WYQ2, Q99476	Gene names	PEX6, PXAAA1
Domain Architecture
Description	Peroxisome assembly factor 2 (PAF-2) (Peroxisomal-type ATPase 1) (Peroxin-6) (Peroxisomal biogenesis factor 6).

PEX6_MOUSE
θ value	1.81305 (rank : 46)	NC score	0.046157 (rank : 53)
Query Neighborhood Hits	88	Target Neighborhood Hits	94	Shared Neighborhood Hits	16
SwissProt Accessions	Q99LC9, Q6YNQ9	Gene names	Pex6
Domain Architecture	No domain graphic available
Description	Peroxisome assembly factor 2 (PAF-2) (Peroxisomal-type ATPase 1) (Peroxin-6) (Peroxisomal biogenesis factor 6).

FBX18_HUMAN
θ value	2.36792 (rank : 47)	NC score	0.044136 (rank : 57)
Query Neighborhood Hits	88	Target Neighborhood Hits	41	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NFZ0, Q7Z4Q6, Q7Z4R0, Q8N1P5, Q8N586, Q96E82, Q96K67, Q96SW7, Q9UFB2	Gene names	FBXO18, FBH1, FBX18
Domain Architecture
Description	F-box only protein 18 (EC 3.6.1.-) (F-box DNA helicase 1).

FOXM1_HUMAN
θ value	2.36792 (rank : 48)	NC score	0.014794 (rank : 91)
Query Neighborhood Hits	88	Target Neighborhood Hits	167	Shared Neighborhood Hits	5
SwissProt Accessions	Q08050, O43258, O43259, O43260, Q4ZGG7, Q9BRL2	Gene names	FOXM1, FKHL16, HFH11, MPP2, WIN
Domain Architecture
Description	Forkhead box protein M1 (Forkhead-related protein FKHL16) (Hepatocyte nuclear factor 3 forkhead homolog 11) (HNF-3/fork-head homolog 11) (HFH-11) (Winged helix factor from INS-1 cells) (M-phase phosphoprotein 2) (MPM-2 reactive phosphoprotein 2) (Transcription factor Trident).

MAST3_HUMAN
θ value	2.36792 (rank : 49)	NC score	0.003245 (rank : 115)
Query Neighborhood Hits	88	Target Neighborhood Hits	1128	Shared Neighborhood Hits	10
SwissProt Accessions	O60307, Q7LDZ8, Q9UPI0	Gene names	MAST3, KIAA0561
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 3 (EC 2.7.11.1).

SPTN4_HUMAN
θ value	2.36792 (rank : 50)	NC score	0.011768 (rank : 95)
Query Neighborhood Hits	88	Target Neighborhood Hits	570	Shared Neighborhood Hits	10
SwissProt Accessions	Q9H254, Q9H1K7, Q9H1K8, Q9H1K9, Q9H3G8, Q9HCD0	Gene names	SPTBN4, KIAA1642, SPTBN3
Domain Architecture
Description	Spectrin beta chain, brain 3 (Spectrin, non-erythroid beta chain 3) (Beta-IV spectrin).

ZN409_HUMAN
θ value	2.36792 (rank : 51)	NC score	0.014833 (rank : 90)
Query Neighborhood Hits	88	Target Neighborhood Hits	842	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UPU6	Gene names	ZNF409, KIAA1056
Domain Architecture	No domain graphic available
Description	Zinc finger protein 409.

AMPD3_HUMAN
θ value	3.0926 (rank : 52)	NC score	0.014893 (rank : 89)
Query Neighborhood Hits	88	Target Neighborhood Hits	33	Shared Neighborhood Hits	2
SwissProt Accessions	Q01432	Gene names	AMPD3
Domain Architecture
Description	AMP deaminase 3 (EC 3.5.4.6) (AMP deaminase isoform E) (Erythrocyte AMP deaminase).

CJ118_MOUSE
θ value	3.0926 (rank : 53)	NC score	0.010809 (rank : 98)
Query Neighborhood Hits	88	Target Neighborhood Hits	1132	Shared Neighborhood Hits	16
SwissProt Accessions	Q8C9S4, Q6P3D6, Q8CJC0	Gene names	Otg1
Domain Architecture	No domain graphic available
Description	Protein C10orf118 homolog (Oocyte-testis gene 1 protein).

CNOT3_MOUSE
θ value	3.0926 (rank : 54)	NC score	0.031158 (rank : 73)
Query Neighborhood Hits	88	Target Neighborhood Hits	504	Shared Neighborhood Hits	15
SwissProt Accessions	Q8K0V4	Gene names	Cnot3, Not3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

K2C6G_MOUSE
θ value	3.0926 (rank : 55)	NC score	0.006678 (rank : 106)
Query Neighborhood Hits	88	Target Neighborhood Hits	452	Shared Neighborhood Hits	9
SwissProt Accessions	Q9R0H5, Q7TPF3, Q9D0X6	Gene names	Krt6g, K6irs1, Krt2-6g
Domain Architecture	No domain graphic available
Description	Keratin, type II cytoskeletal 6G (Cytokeratin-6G) (CK 6G) (K6g keratin) (Keratin-K6irs) (mK6irs1/Krt2-6g).

KLC1_HUMAN
θ value	3.0926 (rank : 56)	NC score	0.022724 (rank : 84)
Query Neighborhood Hits	88	Target Neighborhood Hits	471	Shared Neighborhood Hits	11
SwissProt Accessions	Q07866, Q7RTM2, Q7RTM3, Q7RTM5, Q7RTP9, Q7RTQ5, Q86SF5, Q86TF5, Q86V74, Q86V75, Q86V76, Q86V77, Q86V78, Q86V79, Q96H62	Gene names	KNS2, KLC, KLC1
Domain Architecture
Description	Kinesin light chain 1 (KLC 1).

MRCKB_MOUSE
θ value	3.0926 (rank : 57)	NC score	0.006556 (rank : 107)
Query Neighborhood Hits	88	Target Neighborhood Hits	2180	Shared Neighborhood Hits	23
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

ADRM1_HUMAN
θ value	4.03905 (rank : 58)	NC score	0.026874 (rank : 80)
Query Neighborhood Hits	88	Target Neighborhood Hits	81	Shared Neighborhood Hits	5
SwissProt Accessions	Q16186, Q9H1P2	Gene names	ADRM1, GP110
Domain Architecture
Description	Adhesion-regulating molecule 1 precursor (110 kDa cell membrane glycoprotein) (Gp110).

CAN2_MOUSE
θ value	4.03905 (rank : 59)	NC score	0.007183 (rank : 104)
Query Neighborhood Hits	88	Target Neighborhood Hits	69	Shared Neighborhood Hits	2
SwissProt Accessions	O08529, O35518, O54843	Gene names	Capn2
Domain Architecture
Description	Calpain-2 catalytic subunit precursor (EC 3.4.22.53) (Calpain-2 large subunit) (Calcium-activated neutral proteinase 2) (CANP 2) (Calpain M- type) (M-calpain) (Millimolar-calpain) (80 kDa M-calpain subunit) (CALP80).

K2C6B_MOUSE
θ value	4.03905 (rank : 60)	NC score	0.006133 (rank : 110)
Query Neighborhood Hits	88	Target Neighborhood Hits	506	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Z331	Gene names	Krt6b, K6-beta, Krt2-6b
Domain Architecture	No domain graphic available
Description	Keratin, type II cytoskeletal 6B (Cytokeratin-6B) (CK 6B) (K6b keratin) (Keratin-6 beta) (mK6-beta).

RUVB1_HUMAN
θ value	4.03905 (rank : 61)	NC score	0.038906 (rank : 61)
Query Neighborhood Hits	88	Target Neighborhood Hits	78	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y265, Q9BSX9	Gene names	RUVBL1, NMP238, TIP49, TIP49A
Domain Architecture
Description	RuvB-like 1 (EC 3.6.1.-) (49 kDa TATA box-binding protein-interacting protein) (49 kDa TBP-interacting protein) (TIP49a) (Pontin 52) (Nuclear matrix protein 238) (NMP 238) (54 kDa erythrocyte cytosolic protein) (ECP-54) (TIP60-associated protein 54-alpha) (TAP54-alpha).

RUVB1_MOUSE
θ value	4.03905 (rank : 62)	NC score	0.038901 (rank : 62)
Query Neighborhood Hits	88	Target Neighborhood Hits	78	Shared Neighborhood Hits	13
SwissProt Accessions	P60122, O35753	Gene names	Ruvbl1, Tip49, Tip49a
Domain Architecture
Description	RuvB-like 1 (EC 3.6.1.-) (49 kDa TATA box-binding protein-interacting protein) (49 kDa TBP-interacting protein) (TIP49a) (Pontin 52) (DNA helicase p50).

SCYBG_MOUSE
θ value	4.03905 (rank : 63)	NC score	0.028265 (rank : 79)
Query Neighborhood Hits	88	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BSU2, Q8VE25, Q9EPB3	Gene names	Cxcl16, Srpsox
Domain Architecture	No domain graphic available
Description	Small inducible cytokine B16 precursor (Transmembrane chemokine CXCL16) (SR-PSOX) (Scavenger receptor for phosphatidylserine and oxidized low density lipoprotein).

TCRG1_HUMAN
θ value	4.03905 (rank : 64)	NC score	0.026258 (rank : 82)
Query Neighborhood Hits	88	Target Neighborhood Hits	929	Shared Neighborhood Hits	16
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

TERA_HUMAN
θ value	4.03905 (rank : 65)	NC score	0.033151 (rank : 70)
Query Neighborhood Hits	88	Target Neighborhood Hits	76	Shared Neighborhood Hits	12
SwissProt Accessions	P55072, Q969G7	Gene names	VCP
Domain Architecture
Description	Transitional endoplasmic reticulum ATPase (TER ATPase) (15S Mg(2+)- ATPase p97 subunit) (Valosin-containing protein) (VCP).

TERA_MOUSE
θ value	4.03905 (rank : 66)	NC score	0.033158 (rank : 69)
Query Neighborhood Hits	88	Target Neighborhood Hits	76	Shared Neighborhood Hits	12
SwissProt Accessions	Q01853	Gene names	Vcp
Domain Architecture
Description	Transitional endoplasmic reticulum ATPase (TER ATPase) (15S Mg(2+)- ATPase p97 subunit) (Valosin-containing protein) (VCP).

TR10A_HUMAN
θ value	4.03905 (rank : 67)	NC score	0.016127 (rank : 87)
Query Neighborhood Hits	88	Target Neighborhood Hits	82	Shared Neighborhood Hits	3
SwissProt Accessions	O00220, Q96E62	Gene names	TNFRSF10A, APO2, DR4, TRAILR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10A precursor (Death receptor 4) (TNF-related apoptosis-inducing ligand receptor 1) (TRAIL receptor 1) (TRAIL-R1) (CD261 antigen).

UACA_MOUSE
θ value	4.03905 (rank : 68)	NC score	0.006042 (rank : 111)
Query Neighborhood Hits	88	Target Neighborhood Hits	1620	Shared Neighborhood Hits	17
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

AKAP9_HUMAN
θ value	5.27518 (rank : 69)	NC score	0.010989 (rank : 97)
Query Neighborhood Hits	88	Target Neighborhood Hits	1710	Shared Neighborhood Hits	21
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

ARHGB_HUMAN
θ value	5.27518 (rank : 70)	NC score	0.009154 (rank : 99)
Query Neighborhood Hits	88	Target Neighborhood Hits	375	Shared Neighborhood Hits	7
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

LONM_HUMAN
θ value	5.27518 (rank : 71)	NC score	0.035048 (rank : 64)
Query Neighborhood Hits	88	Target Neighborhood Hits	130	Shared Neighborhood Hits	14
SwissProt Accessions	P36776, P36777, Q9UQ95	Gene names	PRSS15
Domain Architecture
Description	Lon protease homolog, mitochondrial precursor (EC 3.4.21.-) (Lon protease-like protein) (LONP) (LONHs).

PO2F1_MOUSE
θ value	5.27518 (rank : 72)	NC score	0.006839 (rank : 105)
Query Neighborhood Hits	88	Target Neighborhood Hits	408	Shared Neighborhood Hits	6
SwissProt Accessions	P25425, Q61994, Q63891, Q6Y681, Q7TSD0, Q8BT04, Q8K570, Q99JH0, Q9WTZ4, Q9WTZ5, Q9WTZ6	Gene names	Pou2f1, Oct-1, Otf-1, Otf1
Domain Architecture
Description	POU domain, class 2, transcription factor 1 (Octamer-binding transcription factor 1) (Oct-1) (OTF-1) (NF-A1).

SACS_HUMAN
θ value	5.27518 (rank : 73)	NC score	0.014093 (rank : 93)
Query Neighborhood Hits	88	Target Neighborhood Hits	128	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NZJ4, O94835	Gene names	SACS, KIAA0730
Domain Architecture
Description	Sacsin.

SLIT2_HUMAN
θ value	5.27518 (rank : 74)	NC score	0.006546 (rank : 108)
Query Neighborhood Hits	88	Target Neighborhood Hits	708	Shared Neighborhood Hits	8
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

SLIT2_MOUSE
θ value	5.27518 (rank : 75)	NC score	0.006305 (rank : 109)
Query Neighborhood Hits	88	Target Neighborhood Hits	684	Shared Neighborhood Hits	8
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

VTNC_MOUSE
θ value	5.27518 (rank : 76)	NC score	0.019972 (rank : 85)
Query Neighborhood Hits	88	Target Neighborhood Hits	74	Shared Neighborhood Hits	4
SwissProt Accessions	P29788, Q8VII4	Gene names	Vtn
Domain Architecture
Description	Vitronectin precursor (Serum-spreading factor) (S-protein).

EHMT2_HUMAN
θ value	6.88961 (rank : 77)	NC score	0.004792 (rank : 114)
Query Neighborhood Hits	88	Target Neighborhood Hits	498	Shared Neighborhood Hits	8
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

MAP2_HUMAN
θ value	6.88961 (rank : 78)	NC score	0.026659 (rank : 81)
Query Neighborhood Hits	88	Target Neighborhood Hits	348	Shared Neighborhood Hits	10
SwissProt Accessions	P11137, Q99975, Q99976	Gene names	MAP2
Domain Architecture
Description	Microtubule-associated protein 2 (MAP 2) (MAP-2).

NGEF_MOUSE
θ value	6.88961 (rank : 79)	NC score	0.008836 (rank : 101)
Query Neighborhood Hits	88	Target Neighborhood Hits	228	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CHT1, Q8R204, Q923H2, Q9JHT9	Gene names	Ngef
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

PEX1_HUMAN
θ value	6.88961 (rank : 80)	NC score	0.034319 (rank : 66)
Query Neighborhood Hits	88	Target Neighborhood Hits	98	Shared Neighborhood Hits	15
SwissProt Accessions	O43933, Q96S71, Q96S72, Q96S73, Q99994	Gene names	PEX1
Domain Architecture
Description	Peroxisome biogenesis factor 1 (Peroxin-1) (Peroxisome biogenesis disorder protein 1).

PRG4_MOUSE
θ value	6.88961 (rank : 81)	NC score	0.028682 (rank : 77)
Query Neighborhood Hits	88	Target Neighborhood Hits	624	Shared Neighborhood Hits	15
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

DDX58_HUMAN
θ value	8.99809 (rank : 82)	NC score	0.029936 (rank : 75)
Query Neighborhood Hits	88	Target Neighborhood Hits	105	Shared Neighborhood Hits	7
SwissProt Accessions	O95786, Q5HYE1, Q5VYT1, Q9NT04	Gene names	DDX58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

ERCC2_MOUSE
θ value	8.99809 (rank : 83)	NC score	0.014310 (rank : 92)
Query Neighborhood Hits	88	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	O08811, Q9DC01	Gene names	Ercc2, Xpd
Domain Architecture
Description	TFIIH basal transcription factor complex helicase subunit (EC 3.6.1.-) (DNA-repair protein complementing XP-D cells) (Xeroderma pigmentosum group D-complementing protein) (CXPD) (DNA excision repair protein ERCC-2).

FANCC_MOUSE
θ value	8.99809 (rank : 84)	NC score	0.012687 (rank : 94)
Query Neighborhood Hits	88	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	P50652	Gene names	Fancc, Fac, Facc
Domain Architecture
Description	Fanconi anemia group C protein homolog (Protein FACC).

FOXM1_MOUSE
θ value	8.99809 (rank : 85)	NC score	0.011037 (rank : 96)
Query Neighborhood Hits	88	Target Neighborhood Hits	134	Shared Neighborhood Hits	6
SwissProt Accessions	O08696	Gene names	Foxm1, Fkh16
Domain Architecture
Description	Forkhead box protein M1 (Forkhead homolog 16) (Winged-helix transcription factor Trident).

RTN4_HUMAN
θ value	8.99809 (rank : 86)	NC score	0.017076 (rank : 86)
Query Neighborhood Hits	88	Target Neighborhood Hits	357	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NQC3, O94962, Q9BXG5, Q9H212, Q9H3I3, Q9UQ42, Q9Y293, Q9Y2Y7, Q9Y5U6	Gene names	RTN4, KIAA0886, NOGO
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein) (Foocen) (Neuroendocrine-specific protein) (NSP) (Neuroendocrine-specific protein C homolog) (RTN-x) (Reticulon-5).

SCMH1_MOUSE
θ value	8.99809 (rank : 87)	NC score	0.009089 (rank : 100)
Query Neighborhood Hits	88	Target Neighborhood Hits	87	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K214, Q9JME0	Gene names	Scmh1
Domain Architecture	No domain graphic available
Description	Polycomb protein SCMH1 (Sex comb on midleg homolog 1).

TAP1_MOUSE
θ value	8.99809 (rank : 88)	NC score	0.005985 (rank : 112)
Query Neighborhood Hits	88	Target Neighborhood Hits	95	Shared Neighborhood Hits	3
SwissProt Accessions	P21958	Gene names	Tap1, Abcb2, Ham-1, Ham1
Domain Architecture
Description	Antigen peptide transporter 1 (APT1) (Peptide transporter TAP1) (ATP- binding cassette sub-family B member 2) (Histocompatibility antigen modifier 1).

CX048_HUMAN
θ value	θ > 10 (rank : 89)	NC score	0.076438 (rank : 26)
Query Neighborhood Hits	88	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WUE5, Q9NWY8	Gene names	CXorf48
Domain Architecture	No domain graphic available
Description	Protein CXorf48 (Tumor antigen BJ-HCC-20).

KR412_HUMAN
θ value	θ > 10 (rank : 90)	NC score	0.051168 (rank : 49)
Query Neighborhood Hits	88	Target Neighborhood Hits	178	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BQ66, Q495I0	Gene names	KRTAP4-12, KAP4.12, KRTAP4.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12).

KRA45_HUMAN
θ value	θ > 10 (rank : 91)	NC score	0.053186 (rank : 44)
Query Neighborhood Hits	88	Target Neighborhood Hits	194	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BYR2	Gene names	KRTAP4-5, KAP4.5, KRTAP4.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-5 (Keratin-associated protein 4.5) (Ultrahigh sulfur keratin-associated protein 4.5).

KRA47_HUMAN
θ value	θ > 10 (rank : 92)	NC score	0.051626 (rank : 47)
Query Neighborhood Hits	88	Target Neighborhood Hits	204	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BYR0	Gene names	KRTAP4-7, KAP4.7, KRTAP4.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-7 (Keratin-associated protein 4.7) (Ultrahigh sulfur keratin-associated protein 4.7).

KRA92_HUMAN
θ value	θ > 10 (rank : 93)	NC score	0.055090 (rank : 43)
Query Neighborhood Hits	88	Target Neighborhood Hits	198	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BYQ4	Gene names	KRTAP9-2, KAP9.2, KRTAP9.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-2 (Keratin-associated protein 9.2) (Ultrahigh sulfur keratin-associated protein 9.2).

KRA93_HUMAN
θ value	θ > 10 (rank : 94)	NC score	0.050252 (rank : 51)
Query Neighborhood Hits	88	Target Neighborhood Hits	203	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

KRA94_HUMAN
θ value	θ > 10 (rank : 95)	NC score	0.051057 (rank : 50)
Query Neighborhood Hits	88	Target Neighborhood Hits	204	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BYQ2	Gene names	KRTAP9-4, KAP9.4, KRTAP9.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-4 (Keratin-associated protein 9.4) (Ultrahigh sulfur keratin-associated protein 9.4).

KRA98_HUMAN
θ value	θ > 10 (rank : 96)	NC score	0.061707 (rank : 34)
Query Neighborhood Hits	88	Target Neighborhood Hits	185	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

KRA99_HUMAN
θ value	θ > 10 (rank : 97)	NC score	0.058680 (rank : 40)
Query Neighborhood Hits	88	Target Neighborhood Hits	173	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BYP9	Gene names	KRTAP9-9, KAP9.9, KRTAP9.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-9 (Keratin-associated protein 9.9) (Ultrahigh sulfur keratin-associated protein 9.9).

LCE1B_HUMAN
θ value	θ > 10 (rank : 98)	NC score	0.051979 (rank : 46)
Query Neighborhood Hits	88	Target Neighborhood Hits	58	Shared Neighborhood Hits	4
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

LCE1D_HUMAN
θ value	θ > 10 (rank : 99)	NC score	0.059080 (rank : 39)
Query Neighborhood Hits	88	Target Neighborhood Hits	44	Shared Neighborhood Hits	4
SwissProt Accessions	Q5T752	Gene names	LCE1D, LEP4
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1D (Late envelope protein 4).

LCE2B_HUMAN
θ value	θ > 10 (rank : 100)	NC score	0.059259 (rank : 37)
Query Neighborhood Hits	88	Target Neighborhood Hits	50	Shared Neighborhood Hits	4
SwissProt Accessions	O14633	Gene names	LCE2B, LEP10, SPRL1B, XP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2B (Late envelope protein 10) (Small proline-rich-like epidermal differentiation complex protein 1B) (Skin- specific protein Xp5).

LCE2C_HUMAN
θ value	θ > 10 (rank : 101)	NC score	0.064941 (rank : 30)
Query Neighborhood Hits	88	Target Neighborhood Hits	53	Shared Neighborhood Hits	4
SwissProt Accessions	Q5TA81	Gene names	LCE2C, LEP11
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2C (Late envelope protein 11).

LCE2D_HUMAN
θ value	θ > 10 (rank : 102)	NC score	0.073485 (rank : 27)
Query Neighborhood Hits	88	Target Neighborhood Hits	50	Shared Neighborhood Hits	4
SwissProt Accessions	Q5TA82	Gene names	LCE2D, LEP12, SPRL1A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2D (Late envelope protein 12) (Small proline-rich-like epidermal differentiation complex protein 1A).

LCE5A_HUMAN
θ value	θ > 10 (rank : 103)	NC score	0.072660 (rank : 28)
Query Neighborhood Hits	88	Target Neighborhood Hits	43	Shared Neighborhood Hits	4
SwissProt Accessions	Q5TCM9	Gene names	LCE5A, LEP18, SPRL5A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 5A (Late envelope protein 18) (Small proline-rich-like epidermal differentiation complex protein 5A).

MCSP_MOUSE
θ value	θ > 10 (rank : 104)	NC score	0.056430 (rank : 41)
Query Neighborhood Hits	88	Target Neighborhood Hits	108	Shared Neighborhood Hits	4
SwissProt Accessions	P15265, O70613, Q6P8N3	Gene names	Smcp, Mcs, Mcsp
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

NFX1_HUMAN
θ value	θ > 10 (rank : 105)	NC score	0.063834 (rank : 32)
Query Neighborhood Hits	88	Target Neighborhood Hits	405	Shared Neighborhood Hits	4
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

SPR2B_HUMAN
θ value	θ > 10 (rank : 106)	NC score	0.056199 (rank : 42)
Query Neighborhood Hits	88	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	P35325, Q5T528	Gene names	SPRR2B
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2B (SPR-2B).

SPR2B_MOUSE
θ value	θ > 10 (rank : 107)	NC score	0.095435 (rank : 19)
Query Neighborhood Hits	88	Target Neighborhood Hits	51	Shared Neighborhood Hits	4
SwissProt Accessions	O70554, Q7TSB2	Gene names	Sprr2b
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2B.

SPR2D_MOUSE
θ value	θ > 10 (rank : 108)	NC score	0.097988 (rank : 17)
Query Neighborhood Hits	88	Target Neighborhood Hits	61	Shared Neighborhood Hits	4
SwissProt Accessions	O70555	Gene names	Sprr2d
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2D.

SPR2E_HUMAN
θ value	θ > 10 (rank : 109)	NC score	0.085271 (rank : 22)
Query Neighborhood Hits	88	Target Neighborhood Hits	32	Shared Neighborhood Hits	3
SwissProt Accessions	P22531, Q96RM2	Gene names	SPRR2E
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2E (SPR-2E) (Small proline-rich protein II) (SPR-II).

SPR2E_MOUSE
θ value	θ > 10 (rank : 110)	NC score	0.076658 (rank : 25)
Query Neighborhood Hits	88	Target Neighborhood Hits	45	Shared Neighborhood Hits	4
SwissProt Accessions	O70556	Gene names	Sprr2e
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2E.

SPR2F_HUMAN
θ value	θ > 10 (rank : 111)	NC score	0.091923 (rank : 21)
Query Neighborhood Hits	88	Target Neighborhood Hits	33	Shared Neighborhood Hits	3
SwissProt Accessions	Q96RM1	Gene names	SPRR2F
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2F (SPR-2F).

SPR2F_MOUSE
θ value	θ > 10 (rank : 112)	NC score	0.059762 (rank : 36)
Query Neighborhood Hits	88	Target Neighborhood Hits	43	Shared Neighborhood Hits	4
SwissProt Accessions	O70557	Gene names	Sprr2f
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2F.

SPR2G_MOUSE
θ value	θ > 10 (rank : 113)	NC score	0.092373 (rank : 20)
Query Neighborhood Hits	88	Target Neighborhood Hits	53	Shared Neighborhood Hits	4
SwissProt Accessions	O70558	Gene names	Sprr2g
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2G.

SPR2H_MOUSE
θ value	θ > 10 (rank : 114)	NC score	0.084911 (rank : 23)
Query Neighborhood Hits	88	Target Neighborhood Hits	82	Shared Neighborhood Hits	5
SwissProt Accessions	O70559	Gene names	Sprr2h
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2H.

SPR2I_MOUSE
θ value	θ > 10 (rank : 115)	NC score	0.080022 (rank : 24)
Query Neighborhood Hits	88	Target Neighborhood Hits	45	Shared Neighborhood Hits	4
SwissProt Accessions	O70560	Gene names	Sprr2i
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2I.

Hits sorted by NC score

AQR_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	88	Target Neighborhood Hits	88	Shared Neighborhood Hits	88
SwissProt Accessions	O60306, Q2YDX9, Q6IRU8, Q6PIC8	Gene names	AQR, KIAA0560
Domain Architecture	No domain graphic available
Description	Intron-binding protein aquarius (Intron-binding protein of 160 kDa) (IBP160).

AQR_MOUSE
NC score	0.991481 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	88	Target Neighborhood Hits	62	Shared Neighborhood Hits	46
SwissProt Accessions	Q8CFQ3, P97871, Q3U9N1, Q3ULE8, Q80TX8	Gene names	Aqr, Kiaa0560
Domain Architecture	No domain graphic available
Description	Intron-binding protein aquarius.

RENT1_HUMAN
NC score	0.570851 (rank : 3)	θ value	2.97466e-19 (rank : 5)
Query Neighborhood Hits	88	Target Neighborhood Hits	51	Shared Neighborhood Hits	17
SwissProt Accessions	Q92900, O00239, O43343, Q86Z25, Q92842	Gene names	UPF1, KIAA0221, RENT1
Domain Architecture
Description	Regulator of nonsense transcripts 1 (EC 3.6.1.-) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up- frameshift suppressor 1 homolog) (hUpf1).

RENT1_MOUSE
NC score	0.570678 (rank : 4)	θ value	2.97466e-19 (rank : 6)
Query Neighborhood Hits	88	Target Neighborhood Hits	54	Shared Neighborhood Hits	17
SwissProt Accessions	Q9EPU0, Q99PR4	Gene names	Upf1, Rent1
Domain Architecture
Description	Regulator of nonsense transcripts 1 (EC 3.6.1.-) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up- frameshift suppressor 1 homolog) (mUpf1).

ZNFX1_HUMAN
NC score	0.520763 (rank : 5)	θ value	2.27234e-27 (rank : 4)
Query Neighborhood Hits	88	Target Neighborhood Hits	308	Shared Neighborhood Hits	27
SwissProt Accessions	Q9P2E3, Q9BQM7, Q9BQM8, Q9H8C1, Q9H9S2, Q9NUM1, Q9NWW1	Gene names	ZNFX1, KIAA1404
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

ZNFX1_MOUSE
NC score	0.516609 (rank : 6)	θ value	1.73987e-27 (rank : 3)
Query Neighborhood Hits	88	Target Neighborhood Hits	407	Shared Neighborhood Hits	21
SwissProt Accessions	Q8R151, Q3U016, Q3UD71, Q3UEZ0	Gene names	ZNFX1
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

SETX_HUMAN
NC score	0.508597 (rank : 7)	θ value	8.95645e-16 (rank : 7)
Query Neighborhood Hits	88	Target Neighborhood Hits	368	Shared Neighborhood Hits	22
SwissProt Accessions	Q7Z333, O75120, Q3KQX4, Q68DW5, Q6AZD7, Q7Z3J6, Q8WX33, Q9H9D1, Q9NVP9	Gene names	SETX, ALS4, KIAA0625, SCAR1
Domain Architecture
Description	Probable helicase senataxin (EC 3.6.1.-) (SEN1 homolog).

SMBP2_MOUSE
NC score	0.483230 (rank : 8)	θ value	5.62301e-10 (rank : 8)
Query Neighborhood Hits	88	Target Neighborhood Hits	104	Shared Neighborhood Hits	17
SwissProt Accessions	P40694	Gene names	Ighmbp2, Smbp-2, Smbp2
Domain Architecture
Description	DNA-binding protein SMUBP-2 (EC 3.6.1.-) (ATP-dependent helicase IGHMBP2) (Immunoglobulin mu-binding protein 2) (SMUBP-2) (Cardiac transcription factor 1) (CATF1).

SMBP2_HUMAN
NC score	0.478201 (rank : 9)	θ value	2.13673e-09 (rank : 9)
Query Neighborhood Hits	88	Target Neighborhood Hits	107	Shared Neighborhood Hits	17
SwissProt Accessions	P38935, Q00443, Q14177	Gene names	IGHMBP2, SMBP2, SMUBP2
Domain Architecture
Description	DNA-binding protein SMUBP-2 (EC 3.6.1.-) (ATP-dependent helicase IGHMBP2) (Immunoglobulin mu-binding protein 2) (SMUBP-2) (Glial factor 1) (GF-1).

PR285_HUMAN
NC score	0.441107 (rank : 10)	θ value	1.06045e-08 (rank : 10)
Query Neighborhood Hits	88	Target Neighborhood Hits	63	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BYK8, Q3C2G2, Q4VXQ1, Q8TEF3, Q96ND3, Q9C094	Gene names	PRIC285, KIAA1769
Domain Architecture
Description	Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein (EC 3.6.1.-) (ATP-dependent helicase PRIC285) (PPAR-alpha- interacting complex protein 285) (PPAR-gamma DBD-interacting protein 1) (PDIP1).

M10L1_HUMAN
NC score	0.386528 (rank : 11)	θ value	2.88788e-06 (rank : 11)
Query Neighborhood Hits	88	Target Neighborhood Hits	36	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BXT6, Q5TGD5, Q8NBD4, Q9NXW3, Q9UFB3, Q9UGX9	Gene names	MOV10L1
Domain Architecture
Description	Putative helicase Mov10l1 (EC 3.6.1.-) (Moloney leukemia virus 10-like protein 1) (MOV10-like 1).

M10L1_MOUSE
NC score	0.371955 (rank : 12)	θ value	4.1701e-05 (rank : 12)
Query Neighborhood Hits	88	Target Neighborhood Hits	59	Shared Neighborhood Hits	15
SwissProt Accessions	Q99MV5, Q7TPA9, Q8C3W0, Q924C2	Gene names	Mov10l1, Champ
Domain Architecture
Description	Putative helicase Mov10l1 (EC 3.6.1.-) (Moloney leukemia virus 10-like protein 1) (MOV10-like 1) (Cardiac helicase activated by MEF2 protein) (Cardiac-specific RNA helicase).

MOV10_HUMAN
NC score	0.346807 (rank : 13)	θ value	0.00509761 (rank : 14)
Query Neighborhood Hits	88	Target Neighborhood Hits	46	Shared Neighborhood Hits	17
SwissProt Accessions	Q9HCE1, Q8TEF0, Q9BSY3, Q9BUJ9	Gene names	MOV10, KIAA1631
Domain Architecture
Description	Putative helicase MOV-10 (EC 3.6.1.-) (Moloney leukemia virus 10 protein).

MOV10_MOUSE
NC score	0.339734 (rank : 14)	θ value	0.0252991 (rank : 15)
Query Neighborhood Hits	88	Target Neighborhood Hits	39	Shared Neighborhood Hits	17
SwissProt Accessions	P23249, Q9DC64	Gene names	Mov10, Gb110
Domain Architecture
Description	Putative helicase MOV-10 (EC 3.6.1.-) (Moloney leukemia virus 10 protein).

HELZ_HUMAN
NC score	0.337026 (rank : 15)	θ value	0.00390308 (rank : 13)
Query Neighborhood Hits	88	Target Neighborhood Hits	198	Shared Neighborhood Hits	16
SwissProt Accessions	P42694	Gene names	HELZ, KIAA0054
Domain Architecture	No domain graphic available
Description	Probable helicase with zinc-finger domain (EC 3.6.1.-).

RA51D_MOUSE
NC score	0.110258 (rank : 16)	θ value	0.0563607 (rank : 17)
Query Neighborhood Hits	88	Target Neighborhood Hits	18	Shared Neighborhood Hits	4
SwissProt Accessions	O55230	Gene names	Rad51l3, R51h3, Rad51d
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD51 homolog 4 (R51H3) (RAD51-like protein 3).

SPR2D_MOUSE
NC score	0.097988 (rank : 17)	θ value	θ > 10 (rank : 108)
Query Neighborhood Hits	88	Target Neighborhood Hits	61	Shared Neighborhood Hits	4
SwissProt Accessions	O70555	Gene names	Sprr2d
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2D.

RA51D_HUMAN
NC score	0.096362 (rank : 18)	θ value	0.21417 (rank : 21)
Query Neighborhood Hits	88	Target Neighborhood Hits	18	Shared Neighborhood Hits	4
SwissProt Accessions	O75771, O43537, O60355, O75196, O75847, O75848, O76073, O76085, O94908, Q9UFU5	Gene names	RAD51L3, RAD51D
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD51 homolog 4 (R51H3) (RAD51-like protein 3) (TRAD).

SPR2B_MOUSE
NC score	0.095435 (rank : 19)	θ value	θ > 10 (rank : 107)
Query Neighborhood Hits	88	Target Neighborhood Hits	51	Shared Neighborhood Hits	4
SwissProt Accessions	O70554, Q7TSB2	Gene names	Sprr2b
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2B.

SPR2G_MOUSE
NC score	0.092373 (rank : 20)	θ value	θ > 10 (rank : 113)
Query Neighborhood Hits	88	Target Neighborhood Hits	53	Shared Neighborhood Hits	4
SwissProt Accessions	O70558	Gene names	Sprr2g
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2G.

SPR2F_HUMAN
NC score	0.091923 (rank : 21)	θ value	θ > 10 (rank : 111)
Query Neighborhood Hits	88	Target Neighborhood Hits	33	Shared Neighborhood Hits	3
SwissProt Accessions	Q96RM1	Gene names	SPRR2F
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2F (SPR-2F).

SPR2E_HUMAN
NC score	0.085271 (rank : 22)	θ value	θ > 10 (rank : 109)
Query Neighborhood Hits	88	Target Neighborhood Hits	32	Shared Neighborhood Hits	3
SwissProt Accessions	P22531, Q96RM2	Gene names	SPRR2E
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2E (SPR-2E) (Small proline-rich protein II) (SPR-II).

SPR2H_MOUSE
NC score	0.084911 (rank : 23)	θ value	θ > 10 (rank : 114)
Query Neighborhood Hits	88	Target Neighborhood Hits	82	Shared Neighborhood Hits	5
SwissProt Accessions	O70559	Gene names	Sprr2h
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2H.

SPR2I_MOUSE
NC score	0.080022 (rank : 24)	θ value	θ > 10 (rank : 115)
Query Neighborhood Hits	88	Target Neighborhood Hits	45	Shared Neighborhood Hits	4
SwissProt Accessions	O70560	Gene names	Sprr2i
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2I.

SPR2E_MOUSE
NC score	0.076658 (rank : 25)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	88	Target Neighborhood Hits	45	Shared Neighborhood Hits	4
SwissProt Accessions	O70556	Gene names	Sprr2e
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2E.

CX048_HUMAN
NC score	0.076438 (rank : 26)	θ value	θ > 10 (rank : 89)
Query Neighborhood Hits	88	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WUE5, Q9NWY8	Gene names	CXorf48
Domain Architecture	No domain graphic available
Description	Protein CXorf48 (Tumor antigen BJ-HCC-20).

LCE2D_HUMAN
NC score	0.073485 (rank : 27)	θ value	θ > 10 (rank : 102)
Query Neighborhood Hits	88	Target Neighborhood Hits	50	Shared Neighborhood Hits	4
SwissProt Accessions	Q5TA82	Gene names	LCE2D, LEP12, SPRL1A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2D (Late envelope protein 12) (Small proline-rich-like epidermal differentiation complex protein 1A).

LCE5A_HUMAN
NC score	0.072660 (rank : 28)	θ value	θ > 10 (rank : 103)
Query Neighborhood Hits	88	Target Neighborhood Hits	43	Shared Neighborhood Hits	4
SwissProt Accessions	Q5TCM9	Gene names	LCE5A, LEP18, SPRL5A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 5A (Late envelope protein 18) (Small proline-rich-like epidermal differentiation complex protein 5A).

FANCM_HUMAN
NC score	0.067107 (rank : 29)	θ value	0.365318 (rank : 24)
Query Neighborhood Hits	88	Target Neighborhood Hits	210	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IYD8, Q3YFH9, Q8N9X6, Q9HCH6	Gene names	FANCM, KIAA1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog).

LCE2C_HUMAN
NC score	0.064941 (rank : 30)	θ value	θ > 10 (rank : 101)
Query Neighborhood Hits	88	Target Neighborhood Hits	53	Shared Neighborhood Hits	4
SwissProt Accessions	Q5TA81	Gene names	LCE2C, LEP11
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2C (Late envelope protein 11).

FANCM_MOUSE
NC score	0.064866 (rank : 31)	θ value	0.365318 (rank : 25)
Query Neighborhood Hits	88	Target Neighborhood Hits	177	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BGE5, Q69ZF5, Q8BKB7, Q8BUA8	Gene names	Fancm, Kiaa1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein homolog (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM).

NFX1_HUMAN
NC score	0.063834 (rank : 32)	θ value	θ > 10 (rank : 105)
Query Neighborhood Hits	88	Target Neighborhood Hits	405	Shared Neighborhood Hits	4
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

MUC1_MOUSE
NC score	0.062997 (rank : 33)	θ value	0.279714 (rank : 22)
Query Neighborhood Hits	88	Target Neighborhood Hits	388	Shared Neighborhood Hits	18
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

KRA98_HUMAN
NC score	0.061707 (rank : 34)	θ value	θ > 10 (rank : 96)
Query Neighborhood Hits	88	Target Neighborhood Hits	185	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

SELPL_MOUSE
NC score	0.061523 (rank : 35)	θ value	0.279714 (rank : 23)
Query Neighborhood Hits	88	Target Neighborhood Hits	588	Shared Neighborhood Hits	21
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

SPR2F_MOUSE
NC score	0.059762 (rank : 36)	θ value	θ > 10 (rank : 112)
Query Neighborhood Hits	88	Target Neighborhood Hits	43	Shared Neighborhood Hits	4
SwissProt Accessions	O70557	Gene names	Sprr2f
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2F.

LCE2B_HUMAN
NC score	0.059259 (rank : 37)	θ value	θ > 10 (rank : 100)
Query Neighborhood Hits	88	Target Neighborhood Hits	50	Shared Neighborhood Hits	4
SwissProt Accessions	O14633	Gene names	LCE2B, LEP10, SPRL1B, XP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2B (Late envelope protein 10) (Small proline-rich-like epidermal differentiation complex protein 1B) (Skin- specific protein Xp5).

MUC7_HUMAN
NC score	0.059239 (rank : 38)	θ value	0.0330416 (rank : 16)
Query Neighborhood Hits	88	Target Neighborhood Hits	538	Shared Neighborhood Hits	16
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

LCE1D_HUMAN
NC score	0.059080 (rank : 39)	θ value	θ > 10 (rank : 99)
Query Neighborhood Hits	88	Target Neighborhood Hits	44	Shared Neighborhood Hits	4
SwissProt Accessions	Q5T752	Gene names	LCE1D, LEP4
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1D (Late envelope protein 4).

KRA99_HUMAN
NC score	0.058680 (rank : 40)	θ value	θ > 10 (rank : 97)
Query Neighborhood Hits	88	Target Neighborhood Hits	173	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BYP9	Gene names	KRTAP9-9, KAP9.9, KRTAP9.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-9 (Keratin-associated protein 9.9) (Ultrahigh sulfur keratin-associated protein 9.9).

MCSP_MOUSE
NC score	0.056430 (rank : 41)	θ value	θ > 10 (rank : 104)
Query Neighborhood Hits	88	Target Neighborhood Hits	108	Shared Neighborhood Hits	4
SwissProt Accessions	P15265, O70613, Q6P8N3	Gene names	Smcp, Mcs, Mcsp
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

SPR2B_HUMAN
NC score	0.056199 (rank : 42)	θ value	θ > 10 (rank : 106)
Query Neighborhood Hits	88	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	P35325, Q5T528	Gene names	SPRR2B
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2B (SPR-2B).

KRA92_HUMAN
NC score	0.055090 (rank : 43)	θ value	θ > 10 (rank : 93)
Query Neighborhood Hits	88	Target Neighborhood Hits	198	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BYQ4	Gene names	KRTAP9-2, KAP9.2, KRTAP9.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-2 (Keratin-associated protein 9.2) (Ultrahigh sulfur keratin-associated protein 9.2).

KRA45_HUMAN
NC score	0.053186 (rank : 44)	θ value	θ > 10 (rank : 91)
Query Neighborhood Hits	88	Target Neighborhood Hits	194	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BYR2	Gene names	KRTAP4-5, KAP4.5, KRTAP4.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-5 (Keratin-associated protein 4.5) (Ultrahigh sulfur keratin-associated protein 4.5).

MUC5B_HUMAN
NC score	0.052896 (rank : 45)	θ value	0.0961366 (rank : 19)
Query Neighborhood Hits	88	Target Neighborhood Hits	1020	Shared Neighborhood Hits	24
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

LCE1B_HUMAN
NC score	0.051979 (rank : 46)	θ value	θ > 10 (rank : 98)
Query Neighborhood Hits	88	Target Neighborhood Hits	58	Shared Neighborhood Hits	4
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

KRA47_HUMAN
NC score	0.051626 (rank : 47)	θ value	θ > 10 (rank : 92)
Query Neighborhood Hits	88	Target Neighborhood Hits	204	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BYR0	Gene names	KRTAP4-7, KAP4.7, KRTAP4.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-7 (Keratin-associated protein 4.7) (Ultrahigh sulfur keratin-associated protein 4.7).

DDX58_MOUSE
NC score	0.051619 (rank : 48)	θ value	1.06291 (rank : 34)
Query Neighborhood Hits	88	Target Neighborhood Hits	99	Shared Neighborhood Hits	7
SwissProt Accessions	Q6Q899, Q8C320, Q8C5I3, Q8C7T2	Gene names	Ddx58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

KR412_HUMAN
NC score	0.051168 (rank : 49)	θ value	θ > 10 (rank : 90)
Query Neighborhood Hits	88	Target Neighborhood Hits	178	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BQ66, Q495I0	Gene names	KRTAP4-12, KAP4.12, KRTAP4.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12).

KRA94_HUMAN
NC score	0.051057 (rank : 50)	θ value	θ > 10 (rank : 95)
Query Neighborhood Hits	88	Target Neighborhood Hits	204	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BYQ2	Gene names	KRTAP9-4, KAP9.4, KRTAP9.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-4 (Keratin-associated protein 9.4) (Ultrahigh sulfur keratin-associated protein 9.4).

KRA93_HUMAN
NC score	0.050252 (rank : 51)	θ value	θ > 10 (rank : 94)
Query Neighborhood Hits	88	Target Neighborhood Hits	203	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

CCD27_HUMAN
NC score	0.047850 (rank : 52)	θ value	0.0961366 (rank : 18)
Query Neighborhood Hits	88	Target Neighborhood Hits	594	Shared Neighborhood Hits	12
SwissProt Accessions	Q2M243, Q5TBV3, Q96M50	Gene names	CCDC27
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 27.

PEX6_MOUSE
NC score	0.046157 (rank : 53)	θ value	1.81305 (rank : 46)
Query Neighborhood Hits	88	Target Neighborhood Hits	94	Shared Neighborhood Hits	16
SwissProt Accessions	Q99LC9, Q6YNQ9	Gene names	Pex6
Domain Architecture	No domain graphic available
Description	Peroxisome assembly factor 2 (PAF-2) (Peroxisomal-type ATPase 1) (Peroxin-6) (Peroxisomal biogenesis factor 6).

NU214_HUMAN
NC score	0.045340 (rank : 54)	θ value	1.06291 (rank : 35)
Query Neighborhood Hits	88	Target Neighborhood Hits	657	Shared Neighborhood Hits	19
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

PEX6_HUMAN
NC score	0.044821 (rank : 55)	θ value	1.81305 (rank : 45)
Query Neighborhood Hits	88	Target Neighborhood Hits	99	Shared Neighborhood Hits	19
SwissProt Accessions	Q13608, Q8WYQ2, Q99476	Gene names	PEX6, PXAAA1
Domain Architecture
Description	Peroxisome assembly factor 2 (PAF-2) (Peroxisomal-type ATPase 1) (Peroxin-6) (Peroxisomal biogenesis factor 6).

NVL_HUMAN
NC score	0.044220 (rank : 56)	θ value	0.62314 (rank : 27)
Query Neighborhood Hits	88	Target Neighborhood Hits	112	Shared Neighborhood Hits	14
SwissProt Accessions	O15381, Q96EM7	Gene names	NVL
Domain Architecture
Description	Nuclear valosin-containing protein-like (Nuclear VCP-like protein) (NVLp).

FBX18_HUMAN
NC score	0.044136 (rank : 57)	θ value	2.36792 (rank : 47)
Query Neighborhood Hits	88	Target Neighborhood Hits	41	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NFZ0, Q7Z4Q6, Q7Z4R0, Q8N1P5, Q8N586, Q96E82, Q96K67, Q96SW7, Q9UFB2	Gene names	FBXO18, FBH1, FBX18
Domain Architecture
Description	F-box only protein 18 (EC 3.6.1.-) (F-box DNA helicase 1).

NVL_MOUSE
NC score	0.043833 (rank : 58)	θ value	0.62314 (rank : 28)
Query Neighborhood Hits	88	Target Neighborhood Hits	110	Shared Neighborhood Hits	13
SwissProt Accessions	Q9DBY8, Q3USC4, Q8BW27, Q8K2B5	Gene names	Nvl
Domain Architecture
Description	Nuclear valosin-containing protein-like (Nuclear VCP-like protein) (NVLp).

PRG4_HUMAN
NC score	0.041876 (rank : 59)	θ value	0.125558 (rank : 20)
Query Neighborhood Hits	88	Target Neighborhood Hits	764	Shared Neighborhood Hits	20
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

MDC1_MOUSE
NC score	0.041133 (rank : 60)	θ value	1.81305 (rank : 42)
Query Neighborhood Hits	88	Target Neighborhood Hits	998	Shared Neighborhood Hits	26
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

RUVB1_HUMAN
NC score	0.038906 (rank : 61)	θ value	4.03905 (rank : 61)
Query Neighborhood Hits	88	Target Neighborhood Hits	78	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y265, Q9BSX9	Gene names	RUVBL1, NMP238, TIP49, TIP49A
Domain Architecture
Description	RuvB-like 1 (EC 3.6.1.-) (49 kDa TATA box-binding protein-interacting protein) (49 kDa TBP-interacting protein) (TIP49a) (Pontin 52) (Nuclear matrix protein 238) (NMP 238) (54 kDa erythrocyte cytosolic protein) (ECP-54) (TIP60-associated protein 54-alpha) (TAP54-alpha).

RUVB1_MOUSE
NC score	0.038901 (rank : 62)	θ value	4.03905 (rank : 62)
Query Neighborhood Hits	88	Target Neighborhood Hits	78	Shared Neighborhood Hits	13
SwissProt Accessions	P60122, O35753	Gene names	Ruvbl1, Tip49, Tip49a
Domain Architecture
Description	RuvB-like 1 (EC 3.6.1.-) (49 kDa TATA box-binding protein-interacting protein) (49 kDa TBP-interacting protein) (TIP49a) (Pontin 52) (DNA helicase p50).

MUC2_HUMAN
NC score	0.036866 (rank : 63)	θ value	1.38821 (rank : 39)
Query Neighborhood Hits	88	Target Neighborhood Hits	906	Shared Neighborhood Hits	16
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

LONM_HUMAN
NC score	0.035048 (rank : 64)	θ value	5.27518 (rank : 71)
Query Neighborhood Hits	88	Target Neighborhood Hits	130	Shared Neighborhood Hits	14
SwissProt Accessions	P36776, P36777, Q9UQ95	Gene names	PRSS15
Domain Architecture
Description	Lon protease homolog, mitochondrial precursor (EC 3.4.21.-) (Lon protease-like protein) (LONP) (LONHs).

NACAM_MOUSE
NC score	0.034708 (rank : 65)	θ value	1.81305 (rank : 44)
Query Neighborhood Hits	88	Target Neighborhood Hits	1866	Shared Neighborhood Hits	28
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

PEX1_HUMAN
NC score	0.034319 (rank : 66)	θ value	6.88961 (rank : 80)
Query Neighborhood Hits	88	Target Neighborhood Hits	98	Shared Neighborhood Hits	15
SwissProt Accessions	O43933, Q96S71, Q96S72, Q96S73, Q99994	Gene names	PEX1
Domain Architecture
Description	Peroxisome biogenesis factor 1 (Peroxin-1) (Peroxisome biogenesis disorder protein 1).

RD23B_MOUSE
NC score	0.034252 (rank : 67)	θ value	1.06291 (rank : 36)
Query Neighborhood Hits	88	Target Neighborhood Hits	189	Shared Neighborhood Hits	10
SwissProt Accessions	P54728	Gene names	Rad23b, Mhr23b
Domain Architecture
Description	UV excision repair protein RAD23 homolog B (mHR23B) (XP-C repair- complementing complex 58 kDa protein) (p58).

MAP2_MOUSE
NC score	0.033254 (rank : 68)	θ value	0.813845 (rank : 31)
Query Neighborhood Hits	88	Target Neighborhood Hits	342	Shared Neighborhood Hits	13
SwissProt Accessions	P20357	Gene names	Map2, Mtap2
Domain Architecture
Description	Microtubule-associated protein 2 (MAP 2).

TERA_MOUSE
NC score	0.033158 (rank : 69)	θ value	4.03905 (rank : 66)
Query Neighborhood Hits	88	Target Neighborhood Hits	76	Shared Neighborhood Hits	12
SwissProt Accessions	Q01853	Gene names	Vcp
Domain Architecture
Description	Transitional endoplasmic reticulum ATPase (TER ATPase) (15S Mg(2+)- ATPase p97 subunit) (Valosin-containing protein) (VCP).

TERA_HUMAN
NC score	0.033151 (rank : 70)	θ value	4.03905 (rank : 65)
Query Neighborhood Hits	88	Target Neighborhood Hits	76	Shared Neighborhood Hits	12
SwissProt Accessions	P55072, Q969G7	Gene names	VCP
Domain Architecture
Description	Transitional endoplasmic reticulum ATPase (TER ATPase) (15S Mg(2+)- ATPase p97 subunit) (Valosin-containing protein) (VCP).

TCRG1_MOUSE
NC score	0.031589 (rank : 71)	θ value	0.62314 (rank : 29)
Query Neighborhood Hits	88	Target Neighborhood Hits	947	Shared Neighborhood Hits	16
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

MUC1_HUMAN
NC score	0.031548 (rank : 72)	θ value	0.813845 (rank : 32)
Query Neighborhood Hits	88	Target Neighborhood Hits	975	Shared Neighborhood Hits	22
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

CNOT3_MOUSE
NC score	0.031158 (rank : 73)	θ value	3.0926 (rank : 54)
Query Neighborhood Hits	88	Target Neighborhood Hits	504	Shared Neighborhood Hits	15
SwissProt Accessions	Q8K0V4	Gene names	Cnot3, Not3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

ZAN_MOUSE
NC score	0.029959 (rank : 74)	θ value	1.06291 (rank : 37)
Query Neighborhood Hits	88	Target Neighborhood Hits	808	Shared Neighborhood Hits	15
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

DDX58_HUMAN
NC score	0.029936 (rank : 75)	θ value	8.99809 (rank : 82)
Query Neighborhood Hits	88	Target Neighborhood Hits	105	Shared Neighborhood Hits	7
SwissProt Accessions	O95786, Q5HYE1, Q5VYT1, Q9NT04	Gene names	DDX58
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX58 (EC 3.6.1.-) (DEAD-box protein 58) (Retinoic acid-inducible gene 1 protein) (RIG-1) (RIG-I).

NAL10_MOUSE
NC score	0.028872 (rank : 76)	θ value	0.813845 (rank : 33)
Query Neighborhood Hits	88	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CCN1	Gene names	Nalp10, Pynod
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 10.

PRG4_MOUSE
NC score	0.028682 (rank : 77)	θ value	6.88961 (rank : 81)
Query Neighborhood Hits	88	Target Neighborhood Hits	624	Shared Neighborhood Hits	15
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

ZFY27_HUMAN
NC score	0.028416 (rank : 78)	θ value	1.38821 (rank : 40)
Query Neighborhood Hits	88	Target Neighborhood Hits	64	Shared Neighborhood Hits	2
SwissProt Accessions	Q5T4F4, Q5T4F1, Q5T4F2, Q5T4F3, Q8N1K0, Q8N6D6, Q8NCA0, Q8NDE4, Q96M08	Gene names	ZFYVE27
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 27.

SCYBG_MOUSE
NC score	0.028265 (rank : 79)	θ value	4.03905 (rank : 63)
Query Neighborhood Hits	88	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BSU2, Q8VE25, Q9EPB3	Gene names	Cxcl16, Srpsox
Domain Architecture	No domain graphic available
Description	Small inducible cytokine B16 precursor (Transmembrane chemokine CXCL16) (SR-PSOX) (Scavenger receptor for phosphatidylserine and oxidized low density lipoprotein).

ADRM1_HUMAN
NC score	0.026874 (rank : 80)	θ value	4.03905 (rank : 58)
Query Neighborhood Hits	88	Target Neighborhood Hits	81	Shared Neighborhood Hits	5
SwissProt Accessions	Q16186, Q9H1P2	Gene names	ADRM1, GP110
Domain Architecture
Description	Adhesion-regulating molecule 1 precursor (110 kDa cell membrane glycoprotein) (Gp110).

MAP2_HUMAN
NC score	0.026659 (rank : 81)	θ value	6.88961 (rank : 78)
Query Neighborhood Hits	88	Target Neighborhood Hits	348	Shared Neighborhood Hits	10
SwissProt Accessions	P11137, Q99975, Q99976	Gene names	MAP2
Domain Architecture
Description	Microtubule-associated protein 2 (MAP 2) (MAP-2).

TCRG1_HUMAN
NC score	0.026258 (rank : 82)	θ value	4.03905 (rank : 64)
Query Neighborhood Hits	88	Target Neighborhood Hits	929	Shared Neighborhood Hits	16
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

KLC1_MOUSE
NC score	0.024677 (rank : 83)	θ value	1.38821 (rank : 38)
Query Neighborhood Hits	88	Target Neighborhood Hits	357	Shared Neighborhood Hits	10
SwissProt Accessions	O88447	Gene names	Kns2, Klc1
Domain Architecture	No domain graphic available
Description	Kinesin light chain 1 (KLC 1).

KLC1_HUMAN
NC score	0.022724 (rank : 84)	θ value	3.0926 (rank : 56)
Query Neighborhood Hits	88	Target Neighborhood Hits	471	Shared Neighborhood Hits	11
SwissProt Accessions	Q07866, Q7RTM2, Q7RTM3, Q7RTM5, Q7RTP9, Q7RTQ5, Q86SF5, Q86TF5, Q86V74, Q86V75, Q86V76, Q86V77, Q86V78, Q86V79, Q96H62	Gene names	KNS2, KLC, KLC1
Domain Architecture
Description	Kinesin light chain 1 (KLC 1).

VTNC_MOUSE
NC score	0.019972 (rank : 85)	θ value	5.27518 (rank : 76)
Query Neighborhood Hits	88	Target Neighborhood Hits	74	Shared Neighborhood Hits	4
SwissProt Accessions	P29788, Q8VII4	Gene names	Vtn
Domain Architecture
Description	Vitronectin precursor (Serum-spreading factor) (S-protein).

RTN4_HUMAN
NC score	0.017076 (rank : 86)	θ value	8.99809 (rank : 86)
Query Neighborhood Hits	88	Target Neighborhood Hits	357	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NQC3, O94962, Q9BXG5, Q9H212, Q9H3I3, Q9UQ42, Q9Y293, Q9Y2Y7, Q9Y5U6	Gene names	RTN4, KIAA0886, NOGO
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein) (Foocen) (Neuroendocrine-specific protein) (NSP) (Neuroendocrine-specific protein C homolog) (RTN-x) (Reticulon-5).

TR10A_HUMAN
NC score	0.016127 (rank : 87)	θ value	4.03905 (rank : 67)
Query Neighborhood Hits	88	Target Neighborhood Hits	82	Shared Neighborhood Hits	3
SwissProt Accessions	O00220, Q96E62	Gene names	TNFRSF10A, APO2, DR4, TRAILR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10A precursor (Death receptor 4) (TNF-related apoptosis-inducing ligand receptor 1) (TRAIL receptor 1) (TRAIL-R1) (CD261 antigen).

GP1BA_HUMAN
NC score	0.014966 (rank : 88)	θ value	1.81305 (rank : 41)
Query Neighborhood Hits	88	Target Neighborhood Hits	407	Shared Neighborhood Hits	9
SwissProt Accessions	P07359, Q14441, Q16469, Q8N1F3, Q8NG39, Q9HDC7, Q9UEK1, Q9UQS4	Gene names	GP1BA
Domain Architecture
Description	Platelet glycoprotein Ib alpha chain precursor (Glycoprotein Ibalpha) (GP-Ib alpha) (GPIbA) (GPIb-alpha) (Antigen CD42b-alpha) (CD42b antigen) [Contains: Glycocalicin].

AMPD3_HUMAN
NC score	0.014893 (rank : 89)	θ value	3.0926 (rank : 52)
Query Neighborhood Hits	88	Target Neighborhood Hits	33	Shared Neighborhood Hits	2
SwissProt Accessions	Q01432	Gene names	AMPD3
Domain Architecture
Description	AMP deaminase 3 (EC 3.5.4.6) (AMP deaminase isoform E) (Erythrocyte AMP deaminase).

ZN409_HUMAN
NC score	0.014833 (rank : 90)	θ value	2.36792 (rank : 51)
Query Neighborhood Hits	88	Target Neighborhood Hits	842	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UPU6	Gene names	ZNF409, KIAA1056
Domain Architecture	No domain graphic available
Description	Zinc finger protein 409.

FOXM1_HUMAN
NC score	0.014794 (rank : 91)	θ value	2.36792 (rank : 48)
Query Neighborhood Hits	88	Target Neighborhood Hits	167	Shared Neighborhood Hits	5
SwissProt Accessions	Q08050, O43258, O43259, O43260, Q4ZGG7, Q9BRL2	Gene names	FOXM1, FKHL16, HFH11, MPP2, WIN
Domain Architecture
Description	Forkhead box protein M1 (Forkhead-related protein FKHL16) (Hepatocyte nuclear factor 3 forkhead homolog 11) (HNF-3/fork-head homolog 11) (HFH-11) (Winged helix factor from INS-1 cells) (M-phase phosphoprotein 2) (MPM-2 reactive phosphoprotein 2) (Transcription factor Trident).

ERCC2_MOUSE
NC score	0.014310 (rank : 92)	θ value	8.99809 (rank : 83)
Query Neighborhood Hits	88	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	O08811, Q9DC01	Gene names	Ercc2, Xpd
Domain Architecture
Description	TFIIH basal transcription factor complex helicase subunit (EC 3.6.1.-) (DNA-repair protein complementing XP-D cells) (Xeroderma pigmentosum group D-complementing protein) (CXPD) (DNA excision repair protein ERCC-2).

SACS_HUMAN
NC score	0.014093 (rank : 93)	θ value	5.27518 (rank : 73)
Query Neighborhood Hits	88	Target Neighborhood Hits	128	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NZJ4, O94835	Gene names	SACS, KIAA0730
Domain Architecture
Description	Sacsin.

FANCC_MOUSE
NC score	0.012687 (rank : 94)	θ value	8.99809 (rank : 84)
Query Neighborhood Hits	88	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	P50652	Gene names	Fancc, Fac, Facc
Domain Architecture
Description	Fanconi anemia group C protein homolog (Protein FACC).

SPTN4_HUMAN
NC score	0.011768 (rank : 95)	θ value	2.36792 (rank : 50)
Query Neighborhood Hits	88	Target Neighborhood Hits	570	Shared Neighborhood Hits	10
SwissProt Accessions	Q9H254, Q9H1K7, Q9H1K8, Q9H1K9, Q9H3G8, Q9HCD0	Gene names	SPTBN4, KIAA1642, SPTBN3
Domain Architecture
Description	Spectrin beta chain, brain 3 (Spectrin, non-erythroid beta chain 3) (Beta-IV spectrin).

FOXM1_MOUSE
NC score	0.011037 (rank : 96)	θ value	8.99809 (rank : 85)
Query Neighborhood Hits	88	Target Neighborhood Hits	134	Shared Neighborhood Hits	6
SwissProt Accessions	O08696	Gene names	Foxm1, Fkh16
Domain Architecture
Description	Forkhead box protein M1 (Forkhead homolog 16) (Winged-helix transcription factor Trident).

AKAP9_HUMAN
NC score	0.010989 (rank : 97)	θ value	5.27518 (rank : 69)
Query Neighborhood Hits	88	Target Neighborhood Hits	1710	Shared Neighborhood Hits	21
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

CJ118_MOUSE
NC score	0.010809 (rank : 98)	θ value	3.0926 (rank : 53)
Query Neighborhood Hits	88	Target Neighborhood Hits	1132	Shared Neighborhood Hits	16
SwissProt Accessions	Q8C9S4, Q6P3D6, Q8CJC0	Gene names	Otg1
Domain Architecture	No domain graphic available
Description	Protein C10orf118 homolog (Oocyte-testis gene 1 protein).

ARHGB_HUMAN
NC score	0.009154 (rank : 99)	θ value	5.27518 (rank : 70)
Query Neighborhood Hits	88	Target Neighborhood Hits	375	Shared Neighborhood Hits	7
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

SCMH1_MOUSE
NC score	0.009089 (rank : 100)	θ value	8.99809 (rank : 87)
Query Neighborhood Hits	88	Target Neighborhood Hits	87	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K214, Q9JME0	Gene names	Scmh1
Domain Architecture	No domain graphic available
Description	Polycomb protein SCMH1 (Sex comb on midleg homolog 1).

NGEF_MOUSE
NC score	0.008836 (rank : 101)	θ value	6.88961 (rank : 79)
Query Neighborhood Hits	88	Target Neighborhood Hits	228	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CHT1, Q8R204, Q923H2, Q9JHT9	Gene names	Ngef
Domain Architecture	No domain graphic available
Description	Ephexin-1 (Eph-interacting exchange protein) (Neuronal guanine nucleotide exchange factor).

GLI2_HUMAN
NC score	0.007316 (rank : 102)	θ value	0.62314 (rank : 26)
Query Neighborhood Hits	88	Target Neighborhood Hits	971	Shared Neighborhood Hits	6
SwissProt Accessions	P10070, O60252, O60253, O60254, O60255, Q15590, Q15591	Gene names	GLI2, THP
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI2 (Tax helper protein).

MRCKB_HUMAN
NC score	0.007204 (rank : 103)	θ value	1.81305 (rank : 43)
Query Neighborhood Hits	88	Target Neighborhood Hits	2239	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

CAN2_MOUSE
NC score	0.007183 (rank : 104)	θ value	4.03905 (rank : 59)
Query Neighborhood Hits	88	Target Neighborhood Hits	69	Shared Neighborhood Hits	2
SwissProt Accessions	O08529, O35518, O54843	Gene names	Capn2
Domain Architecture
Description	Calpain-2 catalytic subunit precursor (EC 3.4.22.53) (Calpain-2 large subunit) (Calcium-activated neutral proteinase 2) (CANP 2) (Calpain M- type) (M-calpain) (Millimolar-calpain) (80 kDa M-calpain subunit) (CALP80).

PO2F1_MOUSE
NC score	0.006839 (rank : 105)	θ value	5.27518 (rank : 72)
Query Neighborhood Hits	88	Target Neighborhood Hits	408	Shared Neighborhood Hits	6
SwissProt Accessions	P25425, Q61994, Q63891, Q6Y681, Q7TSD0, Q8BT04, Q8K570, Q99JH0, Q9WTZ4, Q9WTZ5, Q9WTZ6	Gene names	Pou2f1, Oct-1, Otf-1, Otf1
Domain Architecture
Description	POU domain, class 2, transcription factor 1 (Octamer-binding transcription factor 1) (Oct-1) (OTF-1) (NF-A1).

K2C6G_MOUSE
NC score	0.006678 (rank : 106)	θ value	3.0926 (rank : 55)
Query Neighborhood Hits	88	Target Neighborhood Hits	452	Shared Neighborhood Hits	9
SwissProt Accessions	Q9R0H5, Q7TPF3, Q9D0X6	Gene names	Krt6g, K6irs1, Krt2-6g
Domain Architecture	No domain graphic available
Description	Keratin, type II cytoskeletal 6G (Cytokeratin-6G) (CK 6G) (K6g keratin) (Keratin-K6irs) (mK6irs1/Krt2-6g).

MRCKB_MOUSE
NC score	0.006556 (rank : 107)	θ value	3.0926 (rank : 57)
Query Neighborhood Hits	88	Target Neighborhood Hits	2180	Shared Neighborhood Hits	23
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

SLIT2_HUMAN
NC score	0.006546 (rank : 108)	θ value	5.27518 (rank : 74)
Query Neighborhood Hits	88	Target Neighborhood Hits	708	Shared Neighborhood Hits	8
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

SLIT2_MOUSE
NC score	0.006305 (rank : 109)	θ value	5.27518 (rank : 75)
Query Neighborhood Hits	88	Target Neighborhood Hits	684	Shared Neighborhood Hits	8
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

K2C6B_MOUSE
NC score	0.006133 (rank : 110)	θ value	4.03905 (rank : 60)
Query Neighborhood Hits	88	Target Neighborhood Hits	506	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Z331	Gene names	Krt6b, K6-beta, Krt2-6b
Domain Architecture	No domain graphic available
Description	Keratin, type II cytoskeletal 6B (Cytokeratin-6B) (CK 6B) (K6b keratin) (Keratin-6 beta) (mK6-beta).

UACA_MOUSE
NC score	0.006042 (rank : 111)	θ value	4.03905 (rank : 68)
Query Neighborhood Hits	88	Target Neighborhood Hits	1620	Shared Neighborhood Hits	17
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

TAP1_MOUSE
NC score	0.005985 (rank : 112)	θ value	8.99809 (rank : 88)
Query Neighborhood Hits	88	Target Neighborhood Hits	95	Shared Neighborhood Hits	3
SwissProt Accessions	P21958	Gene names	Tap1, Abcb2, Ham-1, Ham1
Domain Architecture
Description	Antigen peptide transporter 1 (APT1) (Peptide transporter TAP1) (ATP- binding cassette sub-family B member 2) (Histocompatibility antigen modifier 1).

M3K13_HUMAN
NC score	0.005246 (rank : 113)	θ value	0.813845 (rank : 30)
Query Neighborhood Hits	88	Target Neighborhood Hits	911	Shared Neighborhood Hits	8
SwissProt Accessions	O43283	Gene names	MAP3K13, LZK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 13 (EC 2.7.11.25) (Mixed lineage kinase) (MLK) (Leucine zipper-bearing kinase).

EHMT2_HUMAN
NC score	0.004792 (rank : 114)	θ value	6.88961 (rank : 77)
Query Neighborhood Hits	88	Target Neighborhood Hits	498	Shared Neighborhood Hits	8
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

MAST3_HUMAN
NC score	0.003245 (rank : 115)	θ value	2.36792 (rank : 49)
Query Neighborhood Hits	88	Target Neighborhood Hits	1128	Shared Neighborhood Hits	10
SwissProt Accessions	O60307, Q7LDZ8, Q9UPI0	Gene names	MAST3, KIAA0561
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 3 (EC 2.7.11.1).