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Network neighborhood for query Sequence : SMBP2_MOUSE

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SMBP2_MOUSE
SwissProt Accessions	P40694	Gene names	Ighmbp2, Smbp-2, Smbp2
Domain Architecture
Description	DNA-binding protein SMUBP-2 (EC 3.6.1.-) (ATP-dependent helicase IGHMBP2) (Immunoglobulin mu-binding protein 2) (SMUBP-2) (Cardiac transcription factor 1) (CATF1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SMBP2_HUMAN
θ value	0 (rank : 1)	NC score	0.979198 (rank : 2)
Query Neighborhood Hits	104	Target Neighborhood Hits	107	Shared Neighborhood Hits	38
SwissProt Accessions	P38935, Q00443, Q14177	Gene names	IGHMBP2, SMBP2, SMUBP2
Domain Architecture
Description	DNA-binding protein SMUBP-2 (EC 3.6.1.-) (ATP-dependent helicase IGHMBP2) (Immunoglobulin mu-binding protein 2) (SMUBP-2) (Glial factor 1) (GF-1).

SMBP2_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	104	Target Neighborhood Hits	104	Shared Neighborhood Hits	104
SwissProt Accessions	P40694	Gene names	Ighmbp2, Smbp-2, Smbp2
Domain Architecture
Description	DNA-binding protein SMUBP-2 (EC 3.6.1.-) (ATP-dependent helicase IGHMBP2) (Immunoglobulin mu-binding protein 2) (SMUBP-2) (Cardiac transcription factor 1) (CATF1).

RENT1_HUMAN
θ value	1.15895e-47 (rank : 3)	NC score	0.816595 (rank : 3)
Query Neighborhood Hits	104	Target Neighborhood Hits	51	Shared Neighborhood Hits	15
SwissProt Accessions	Q92900, O00239, O43343, Q86Z25, Q92842	Gene names	UPF1, KIAA0221, RENT1
Domain Architecture
Description	Regulator of nonsense transcripts 1 (EC 3.6.1.-) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up- frameshift suppressor 1 homolog) (hUpf1).

RENT1_MOUSE
θ value	1.51363e-47 (rank : 4)	NC score	0.816413 (rank : 4)
Query Neighborhood Hits	104	Target Neighborhood Hits	54	Shared Neighborhood Hits	15
SwissProt Accessions	Q9EPU0, Q99PR4	Gene names	Upf1, Rent1
Domain Architecture
Description	Regulator of nonsense transcripts 1 (EC 3.6.1.-) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up- frameshift suppressor 1 homolog) (mUpf1).

SETX_HUMAN
θ value	9.52487e-34 (rank : 5)	NC score	0.712045 (rank : 8)
Query Neighborhood Hits	104	Target Neighborhood Hits	368	Shared Neighborhood Hits	28
SwissProt Accessions	Q7Z333, O75120, Q3KQX4, Q68DW5, Q6AZD7, Q7Z3J6, Q8WX33, Q9H9D1, Q9NVP9	Gene names	SETX, ALS4, KIAA0625, SCAR1
Domain Architecture
Description	Probable helicase senataxin (EC 3.6.1.-) (SEN1 homolog).

PR285_HUMAN
θ value	8.3442e-30 (rank : 6)	NC score	0.714336 (rank : 5)
Query Neighborhood Hits	104	Target Neighborhood Hits	63	Shared Neighborhood Hits	18
SwissProt Accessions	Q9BYK8, Q3C2G2, Q4VXQ1, Q8TEF3, Q96ND3, Q9C094	Gene names	PRIC285, KIAA1769
Domain Architecture
Description	Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein (EC 3.6.1.-) (ATP-dependent helicase PRIC285) (PPAR-alpha- interacting complex protein 285) (PPAR-gamma DBD-interacting protein 1) (PDIP1).

M10L1_HUMAN
θ value	4.14116e-29 (rank : 7)	NC score	0.713428 (rank : 7)
Query Neighborhood Hits	104	Target Neighborhood Hits	36	Shared Neighborhood Hits	19
SwissProt Accessions	Q9BXT6, Q5TGD5, Q8NBD4, Q9NXW3, Q9UFB3, Q9UGX9	Gene names	MOV10L1
Domain Architecture
Description	Putative helicase Mov10l1 (EC 3.6.1.-) (Moloney leukemia virus 10-like protein 1) (MOV10-like 1).

MOV10_MOUSE
θ value	2.35151e-24 (rank : 8)	NC score	0.713571 (rank : 6)
Query Neighborhood Hits	104	Target Neighborhood Hits	39	Shared Neighborhood Hits	20
SwissProt Accessions	P23249, Q9DC64	Gene names	Mov10, Gb110
Domain Architecture
Description	Putative helicase MOV-10 (EC 3.6.1.-) (Moloney leukemia virus 10 protein).

MOV10_HUMAN
θ value	1.5242e-23 (rank : 9)	NC score	0.711502 (rank : 9)
Query Neighborhood Hits	104	Target Neighborhood Hits	46	Shared Neighborhood Hits	20
SwissProt Accessions	Q9HCE1, Q8TEF0, Q9BSY3, Q9BUJ9	Gene names	MOV10, KIAA1631
Domain Architecture
Description	Putative helicase MOV-10 (EC 3.6.1.-) (Moloney leukemia virus 10 protein).

M10L1_MOUSE
θ value	2.69047e-20 (rank : 10)	NC score	0.695654 (rank : 10)
Query Neighborhood Hits	104	Target Neighborhood Hits	59	Shared Neighborhood Hits	20
SwissProt Accessions	Q99MV5, Q7TPA9, Q8C3W0, Q924C2	Gene names	Mov10l1, Champ
Domain Architecture
Description	Putative helicase Mov10l1 (EC 3.6.1.-) (Moloney leukemia virus 10-like protein 1) (MOV10-like 1) (Cardiac helicase activated by MEF2 protein) (Cardiac-specific RNA helicase).

ZNFX1_MOUSE
θ value	2.20605e-14 (rank : 11)	NC score	0.476346 (rank : 14)
Query Neighborhood Hits	104	Target Neighborhood Hits	407	Shared Neighborhood Hits	20
SwissProt Accessions	Q8R151, Q3U016, Q3UD71, Q3UEZ0	Gene names	ZNFX1
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

HELZ_HUMAN
θ value	4.16044e-13 (rank : 12)	NC score	0.625801 (rank : 11)
Query Neighborhood Hits	104	Target Neighborhood Hits	198	Shared Neighborhood Hits	22
SwissProt Accessions	P42694	Gene names	HELZ, KIAA0054
Domain Architecture	No domain graphic available
Description	Probable helicase with zinc-finger domain (EC 3.6.1.-).

ZNFX1_HUMAN
θ value	5.43371e-13 (rank : 13)	NC score	0.472511 (rank : 15)
Query Neighborhood Hits	104	Target Neighborhood Hits	308	Shared Neighborhood Hits	22
SwissProt Accessions	Q9P2E3, Q9BQM7, Q9BQM8, Q9H8C1, Q9H9S2, Q9NUM1, Q9NWW1	Gene names	ZNFX1, KIAA1404
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

AQR_HUMAN
θ value	5.62301e-10 (rank : 14)	NC score	0.483230 (rank : 13)
Query Neighborhood Hits	104	Target Neighborhood Hits	88	Shared Neighborhood Hits	17
SwissProt Accessions	O60306, Q2YDX9, Q6IRU8, Q6PIC8	Gene names	AQR, KIAA0560
Domain Architecture	No domain graphic available
Description	Intron-binding protein aquarius (Intron-binding protein of 160 kDa) (IBP160).

AQR_MOUSE
θ value	5.62301e-10 (rank : 15)	NC score	0.486195 (rank : 12)
Query Neighborhood Hits	104	Target Neighborhood Hits	62	Shared Neighborhood Hits	17
SwissProt Accessions	Q8CFQ3, P97871, Q3U9N1, Q3ULE8, Q80TX8	Gene names	Aqr, Kiaa0560
Domain Architecture	No domain graphic available
Description	Intron-binding protein aquarius.

NKRF_MOUSE
θ value	0.00228821 (rank : 16)	NC score	0.118952 (rank : 17)
Query Neighborhood Hits	104	Target Neighborhood Hits	67	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BY02, Q8BJU5, Q9CRL2	Gene names	Nkrf, Nrf
Domain Architecture
Description	NF-kappa-B-repressing factor (NFKB-repressing factor) (Transcription factor NRF).

GLI1_HUMAN
θ value	0.00869519 (rank : 17)	NC score	0.009089 (rank : 94)
Query Neighborhood Hits	104	Target Neighborhood Hits	828	Shared Neighborhood Hits	3
SwissProt Accessions	P08151, Q8TDN9	Gene names	GLI1, GLI
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI1 (Glioma-associated oncogene) (Oncogene GLI).

NKRF_HUMAN
θ value	0.0252991 (rank : 18)	NC score	0.110040 (rank : 18)
Query Neighborhood Hits	104	Target Neighborhood Hits	57	Shared Neighborhood Hits	4
SwissProt Accessions	O15226, Q9UJ91	Gene names	NKRF, ITBA4, NRF
Domain Architecture
Description	NF-kappa-B-repressing factor (NFKB-repressing factor) (Transcription factor NRF) (ITBA4 protein).

PEX6_MOUSE
θ value	0.0252991 (rank : 19)	NC score	0.048294 (rank : 32)
Query Neighborhood Hits	104	Target Neighborhood Hits	94	Shared Neighborhood Hits	12
SwissProt Accessions	Q99LC9, Q6YNQ9	Gene names	Pex6
Domain Architecture	No domain graphic available
Description	Peroxisome assembly factor 2 (PAF-2) (Peroxisomal-type ATPase 1) (Peroxin-6) (Peroxisomal biogenesis factor 6).

DHX57_MOUSE
θ value	0.0431538 (rank : 20)	NC score	0.069688 (rank : 20)
Query Neighborhood Hits	104	Target Neighborhood Hits	125	Shared Neighborhood Hits	13
SwissProt Accessions	Q6P5D3, Q3TS93, Q6NZK4, Q6P1B4, Q8BI63, Q8BIA2, Q8R360	Gene names	Dhx57
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX57 (EC 3.6.1.-) (DEAH box protein 57).

DHX57_HUMAN
θ value	0.0736092 (rank : 21)	NC score	0.067839 (rank : 22)
Query Neighborhood Hits	104	Target Neighborhood Hits	109	Shared Neighborhood Hits	13
SwissProt Accessions	Q6P158, Q53SI4, Q6P9G1, Q7Z6H3, Q8NG17, Q96M33	Gene names	DHX57
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX57 (EC 3.6.1.-) (DEAH box protein 57).

MAST4_HUMAN
θ value	0.0736092 (rank : 22)	NC score	0.011767 (rank : 85)
Query Neighborhood Hits	104	Target Neighborhood Hits	1804	Shared Neighborhood Hits	34
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

SC24D_HUMAN
θ value	0.0736092 (rank : 23)	NC score	0.041734 (rank : 40)
Query Neighborhood Hits	104	Target Neighborhood Hits	173	Shared Neighborhood Hits	5
SwissProt Accessions	O94855	Gene names	SEC24D, KIAA0755
Domain Architecture
Description	Protein transport protein Sec24D (SEC24-related protein D).

PKCB1_HUMAN
θ value	0.125558 (rank : 24)	NC score	0.036130 (rank : 46)
Query Neighborhood Hits	104	Target Neighborhood Hits	488	Shared Neighborhood Hits	14
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

TRP13_HUMAN
θ value	0.125558 (rank : 25)	NC score	0.074802 (rank : 19)
Query Neighborhood Hits	104	Target Neighborhood Hits	81	Shared Neighborhood Hits	13
SwissProt Accessions	Q15645, O15324	Gene names	TRIP13
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 13 (Thyroid hormone receptor interactor 13) (Trip-13) (Human papillomavirus type 16 E1 protein- binding protein) (HPV16 E1 protein-binding protein) (16E1-BP).

HORN_HUMAN
θ value	0.279714 (rank : 26)	NC score	0.036999 (rank : 44)
Query Neighborhood Hits	104	Target Neighborhood Hits	206	Shared Neighborhood Hits	11
SwissProt Accessions	Q86YZ3	Gene names	HRNR, S100A18
Domain Architecture	No domain graphic available
Description	Hornerin.

TRP13_MOUSE
θ value	0.279714 (rank : 27)	NC score	0.069472 (rank : 21)
Query Neighborhood Hits	104	Target Neighborhood Hits	81	Shared Neighborhood Hits	13
SwissProt Accessions	Q3UA06, Q3UQG6, Q9CWW8	Gene names	Trip13
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 13 (Thyroid hormone receptor interactor 13) (Trip-13).

DHX36_MOUSE
θ value	0.365318 (rank : 28)	NC score	0.054623 (rank : 29)
Query Neighborhood Hits	104	Target Neighborhood Hits	114	Shared Neighborhood Hits	11
SwissProt Accessions	Q8VHK9, Q6ZPP7, Q9CSE8	Gene names	Dhx36, Ddx36, Kiaa1488, Mlel1
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX36 (EC 3.6.1.-) (DEAH box protein 36) (MLE-like protein 1) (RNA helicase associated with AU-rich element ARE).

NCOR2_MOUSE
θ value	0.365318 (rank : 29)	NC score	0.037713 (rank : 43)
Query Neighborhood Hits	104	Target Neighborhood Hits	790	Shared Neighborhood Hits	23
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

ELOA2_HUMAN
θ value	0.47712 (rank : 30)	NC score	0.033950 (rank : 48)
Query Neighborhood Hits	104	Target Neighborhood Hits	165	Shared Neighborhood Hits	9
SwissProt Accessions	Q8IYF1, Q9P2V9	Gene names	TCEB3B, TCEB3L
Domain Architecture
Description	RNA polymerase II transcription factor SIII subunit A2 (Elongin-A2) (EloA2) (Transcription elongation factor B polypeptide 3B).

CCNT2_HUMAN
θ value	0.62314 (rank : 31)	NC score	0.028419 (rank : 55)
Query Neighborhood Hits	104	Target Neighborhood Hits	84	Shared Neighborhood Hits	5
SwissProt Accessions	O60583, O60582, Q5I1Y0	Gene names	CCNT2
Domain Architecture
Description	Cyclin-T2 (CycT2).

DHX16_HUMAN
θ value	0.62314 (rank : 32)	NC score	0.044471 (rank : 35)
Query Neighborhood Hits	104	Target Neighborhood Hits	356	Shared Neighborhood Hits	19
SwissProt Accessions	O60231, O60322, Q969X7, Q96QC1	Gene names	DHX16, DBP2, DDX16, KIAA0577
Domain Architecture
Description	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 (EC 3.6.1.-) (DEAH-box protein 16) (ATP-dependent RNA helicase #3).

K1683_HUMAN
θ value	0.62314 (rank : 33)	NC score	0.036726 (rank : 45)
Query Neighborhood Hits	104	Target Neighborhood Hits	240	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H0B3, Q8N4G8, Q96M14, Q9C0I0	Gene names	KIAA1683
Domain Architecture	No domain graphic available
Description	Protein KIAA1683.

CUTL1_HUMAN
θ value	0.813845 (rank : 34)	NC score	0.016910 (rank : 74)
Query Neighborhood Hits	104	Target Neighborhood Hits	1574	Shared Neighborhood Hits	28
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

FILA_HUMAN
θ value	0.813845 (rank : 35)	NC score	0.037737 (rank : 42)
Query Neighborhood Hits	104	Target Neighborhood Hits	685	Shared Neighborhood Hits	28
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

LMO6_HUMAN
θ value	0.813845 (rank : 36)	NC score	0.013218 (rank : 80)
Query Neighborhood Hits	104	Target Neighborhood Hits	337	Shared Neighborhood Hits	3
SwissProt Accessions	O43900, O76007	Gene names	LMO6
Domain Architecture
Description	LIM domain only protein 6 (Triple LIM domain protein 6).

PHAR2_HUMAN
θ value	0.813845 (rank : 37)	NC score	0.032023 (rank : 49)
Query Neighborhood Hits	104	Target Neighborhood Hits	208	Shared Neighborhood Hits	10
SwissProt Accessions	O75167, Q68DM2	Gene names	PHACTR2, C6orf56, KIAA0680
Domain Architecture	No domain graphic available
Description	Phosphatase and actin regulator 2.

NCOR2_HUMAN
θ value	1.06291 (rank : 38)	NC score	0.034861 (rank : 47)
Query Neighborhood Hits	104	Target Neighborhood Hits	870	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

PEG3_MOUSE
θ value	1.06291 (rank : 39)	NC score	0.003010 (rank : 109)
Query Neighborhood Hits	104	Target Neighborhood Hits	1101	Shared Neighborhood Hits	13
SwissProt Accessions	Q3URU2, O54978, Q3TQ69, Q5EBP7, Q61138, Q6GQS0, Q80U47, Q8R5N0, Q9QX53	Gene names	Peg3, Kiaa0287, Pw1
Domain Architecture	No domain graphic available
Description	Paternally expressed gene 3 protein (ASF-1).

PEX6_HUMAN
θ value	1.06291 (rank : 40)	NC score	0.041602 (rank : 41)
Query Neighborhood Hits	104	Target Neighborhood Hits	99	Shared Neighborhood Hits	14
SwissProt Accessions	Q13608, Q8WYQ2, Q99476	Gene names	PEX6, PXAAA1
Domain Architecture
Description	Peroxisome assembly factor 2 (PAF-2) (Peroxisomal-type ATPase 1) (Peroxin-6) (Peroxisomal biogenesis factor 6).

AFF4_HUMAN
θ value	1.38821 (rank : 41)	NC score	0.028487 (rank : 54)
Query Neighborhood Hits	104	Target Neighborhood Hits	611	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

CTND2_MOUSE
θ value	1.38821 (rank : 42)	NC score	0.015361 (rank : 75)
Query Neighborhood Hits	104	Target Neighborhood Hits	227	Shared Neighborhood Hits	10
SwissProt Accessions	O35927	Gene names	Ctnnd2, Catnd2, Nprap
Domain Architecture
Description	Catenin delta-2 (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin).

OBSCN_HUMAN
θ value	1.38821 (rank : 43)	NC score	0.004024 (rank : 106)
Query Neighborhood Hits	104	Target Neighborhood Hits	1931	Shared Neighborhood Hits	18
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

SCN4A_HUMAN
θ value	1.38821 (rank : 44)	NC score	0.008658 (rank : 97)
Query Neighborhood Hits	104	Target Neighborhood Hits	133	Shared Neighborhood Hits	3
SwissProt Accessions	P35499, Q15478, Q16447, Q7Z6B1	Gene names	SCN4A
Domain Architecture
Description	Sodium channel protein type 4 subunit alpha (Sodium channel protein type IV subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.4) (Sodium channel protein, skeletal muscle subunit alpha) (SkM1).

SYN1_HUMAN
θ value	1.38821 (rank : 45)	NC score	0.027352 (rank : 57)
Query Neighborhood Hits	104	Target Neighborhood Hits	419	Shared Neighborhood Hits	14
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

DHX8_HUMAN
θ value	1.81305 (rank : 46)	NC score	0.043088 (rank : 38)
Query Neighborhood Hits	104	Target Neighborhood Hits	86	Shared Neighborhood Hits	11
SwissProt Accessions	Q14562	Gene names	DHX8, DDX8
Domain Architecture
Description	ATP-dependent RNA helicase DHX8 (EC 3.6.1.-) (DEAH box protein 8) (RNA helicase HRH1).

DHX9_HUMAN
θ value	1.81305 (rank : 47)	NC score	0.048532 (rank : 31)
Query Neighborhood Hits	104	Target Neighborhood Hits	62	Shared Neighborhood Hits	9
SwissProt Accessions	Q08211, Q5VY62, Q6PD69, Q99556	Gene names	DHX9, DDX9, NDH2
Domain Architecture
Description	ATP-dependent RNA helicase A (EC 3.6.1.-) (Nuclear DNA helicase II) (NDH II) (DEAH box protein 9).

TOP2A_HUMAN
θ value	1.81305 (rank : 48)	NC score	0.017543 (rank : 72)
Query Neighborhood Hits	104	Target Neighborhood Hits	135	Shared Neighborhood Hits	8
SwissProt Accessions	P11388, Q71UN1, Q9HB24, Q9HB25, Q9HB26, Q9UP44, Q9UQP9	Gene names	TOP2A, TOP2
Domain Architecture
Description	DNA topoisomerase 2-alpha (EC 5.99.1.3) (DNA topoisomerase II, alpha isozyme).

ABRA_HUMAN
θ value	2.36792 (rank : 49)	NC score	0.026221 (rank : 58)
Query Neighborhood Hits	104	Target Neighborhood Hits	52	Shared Neighborhood Hits	5
SwissProt Accessions	Q8N0Z2	Gene names	ABRA
Domain Architecture	No domain graphic available
Description	Actin-binding Rho-activating protein (Striated muscle activator of Rho-dependent signaling) (STARS).

BSN_MOUSE
θ value	2.36792 (rank : 50)	NC score	0.021873 (rank : 63)
Query Neighborhood Hits	104	Target Neighborhood Hits	2057	Shared Neighborhood Hits	35
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CLMN_HUMAN
θ value	2.36792 (rank : 51)	NC score	0.011032 (rank : 87)
Query Neighborhood Hits	104	Target Neighborhood Hits	205	Shared Neighborhood Hits	7
SwissProt Accessions	Q96JQ2, Q9H713, Q9HA23, Q9HA57, Q9UFP4, Q9ULN2	Gene names	CLMN, KIAA1188
Domain Architecture
Description	Calmin.

CUTL2_HUMAN
θ value	2.36792 (rank : 52)	NC score	0.023854 (rank : 62)
Query Neighborhood Hits	104	Target Neighborhood Hits	906	Shared Neighborhood Hits	21
SwissProt Accessions	O14529	Gene names	CUTL2, KIAA0293
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

PEO1_HUMAN
θ value	2.36792 (rank : 53)	NC score	0.045748 (rank : 34)
Query Neighborhood Hits	104	Target Neighborhood Hits	18	Shared Neighborhood Hits	8
SwissProt Accessions	Q96RR1, Q6MZX2, Q96RR0	Gene names	PEO1, C10orf2
Domain Architecture	No domain graphic available
Description	Twinkle protein, mitochondrial precursor (EC 3.6.1.-) (T7 gp4-like protein with intramitochondrial nucleoid localization) (T7-like mitochondrial DNA helicase) (Progressive external ophthalmoplegia 1 protein).

ABCF2_MOUSE
θ value	3.0926 (rank : 54)	NC score	0.011336 (rank : 86)
Query Neighborhood Hits	104	Target Neighborhood Hits	111	Shared Neighborhood Hits	2
SwissProt Accessions	Q99LE6, Q3UA24, Q8C1S5, Q9JL48	Gene names	Abcf2
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 2.

DHX37_HUMAN
θ value	3.0926 (rank : 55)	NC score	0.042864 (rank : 39)
Query Neighborhood Hits	104	Target Neighborhood Hits	133	Shared Neighborhood Hits	13
SwissProt Accessions	Q8IY37, Q9BUI7, Q9P211	Gene names	DHX37, DDX37, KIAA1517
Domain Architecture
Description	Probable ATP-dependent RNA helicase DHX37 (EC 3.6.1.-) (DEAH box protein 37).

GRIN1_HUMAN
θ value	3.0926 (rank : 56)	NC score	0.020950 (rank : 65)
Query Neighborhood Hits	104	Target Neighborhood Hits	681	Shared Neighborhood Hits	20
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

KTNA1_MOUSE
θ value	3.0926 (rank : 57)	NC score	0.018451 (rank : 71)
Query Neighborhood Hits	104	Target Neighborhood Hits	123	Shared Neighborhood Hits	7
SwissProt Accessions	Q9WV86	Gene names	Katna1
Domain Architecture	No domain graphic available
Description	Katanin p60 ATPase-containing subunit A1 (EC 3.6.4.3) (Katanin p60 subunit A1) (p60 katanin) (Lipotransin).

MSH6_MOUSE
θ value	3.0926 (rank : 58)	NC score	0.014391 (rank : 77)
Query Neighborhood Hits	104	Target Neighborhood Hits	55	Shared Neighborhood Hits	4
SwissProt Accessions	P54276, O54710	Gene names	Msh6, Gtmbp
Domain Architecture
Description	DNA mismatch repair protein MSH6 (MutS-alpha 160 kDa subunit) (G/T mismatch-binding protein) (GTBP) (GTMBP) (p160).

NPBL_MOUSE
θ value	3.0926 (rank : 59)	NC score	0.024734 (rank : 60)
Query Neighborhood Hits	104	Target Neighborhood Hits	1041	Shared Neighborhood Hits	35
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

PEO1_MOUSE
θ value	3.0926 (rank : 60)	NC score	0.043944 (rank : 36)
Query Neighborhood Hits	104	Target Neighborhood Hits	27	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CIW5, Q8K1Z1	Gene names	Peo1
Domain Architecture	No domain graphic available
Description	Twinkle protein, mitochondrial precursor (EC 3.6.1.-) (T7 gp4-like protein with intramitochondrial nucleoid localization) (T7-like mitochondrial DNA helicase) (Progressive external ophthalmoplegia 1 protein homolog).

RA51B_HUMAN
θ value	3.0926 (rank : 61)	NC score	0.018939 (rank : 70)
Query Neighborhood Hits	104	Target Neighborhood Hits	28	Shared Neighborhood Hits	6
SwissProt Accessions	O15315, O60914, O75210, Q3Y4F8, Q86SY3, Q86SY4, Q86TR0, Q86U92, Q86U93, Q86U94, Q8N6H4, Q9UPL5	Gene names	RAD51L1, RAD51B, REC2
Domain Architecture
Description	DNA repair protein RAD51 homolog 2 (R51H2) (RAD51-like protein 1) (Rad51B).

SYN1_MOUSE
θ value	3.0926 (rank : 62)	NC score	0.024015 (rank : 61)
Query Neighborhood Hits	104	Target Neighborhood Hits	363	Shared Neighborhood Hits	13
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

TGON2_HUMAN
θ value	3.0926 (rank : 63)	NC score	0.020831 (rank : 66)
Query Neighborhood Hits	104	Target Neighborhood Hits	1037	Shared Neighborhood Hits	33
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

TMC2_HUMAN
θ value	3.0926 (rank : 64)	NC score	0.015320 (rank : 76)
Query Neighborhood Hits	104	Target Neighborhood Hits	149	Shared Neighborhood Hits	8
SwissProt Accessions	Q8TDI7, Q5JXT0, Q5JXT1, Q6UWW4, Q6ZS41, Q8N9F3, Q9BYN2, Q9BYN3, Q9BYN4, Q9BYN5	Gene names	TMC2
Domain Architecture	No domain graphic available
Description	Transmembrane cochlear-expressed protein 2.

ASPX_HUMAN
θ value	4.03905 (rank : 65)	NC score	0.025890 (rank : 59)
Query Neighborhood Hits	104	Target Neighborhood Hits	148	Shared Neighborhood Hits	9
SwissProt Accessions	P26436	Gene names	ACRV1
Domain Architecture
Description	Acrosomal protein SP-10 precursor (Acrosomal vesicle protein 1).

MAST1_MOUSE
θ value	4.03905 (rank : 66)	NC score	0.003841 (rank : 107)
Query Neighborhood Hits	104	Target Neighborhood Hits	1123	Shared Neighborhood Hits	9
SwissProt Accessions	Q9R1L5, Q7TQG9, Q80TN0	Gene names	Mast1, Kiaa0973, Sast
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

PRP4B_MOUSE
θ value	4.03905 (rank : 67)	NC score	0.006880 (rank : 103)
Query Neighborhood Hits	104	Target Neighborhood Hits	1040	Shared Neighborhood Hits	21
SwissProt Accessions	Q61136, O88378, Q8BND8, Q8R4Y5, Q9CTL9, Q9CTT0	Gene names	Prpf4b, Cbp143, Prp4h, Prp4k, Prp4m, Prpk
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (Pre-mRNA protein kinase).

R3HD2_MOUSE
θ value	4.03905 (rank : 68)	NC score	0.020427 (rank : 68)
Query Neighborhood Hits	104	Target Neighborhood Hits	397	Shared Neighborhood Hits	10
SwissProt Accessions	Q80TM6, Q80YB1, Q8BLS5, Q9CW50	Gene names	R3hdm2, Kiaa1002
Domain Architecture
Description	R3H domain-containing protein 2.

RUSC2_MOUSE
θ value	4.03905 (rank : 69)	NC score	0.017061 (rank : 73)
Query Neighborhood Hits	104	Target Neighborhood Hits	305	Shared Neighborhood Hits	12
SwissProt Accessions	Q80U22, Q8R1D6	Gene names	Rusc2, Kiaa0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

DYHC_HUMAN
θ value	5.27518 (rank : 70)	NC score	0.028913 (rank : 53)
Query Neighborhood Hits	104	Target Neighborhood Hits	733	Shared Neighborhood Hits	21
SwissProt Accessions	Q14204, Q6DKQ7, Q8WU28, Q92814, Q9Y4G5	Gene names	DYNC1H1, DNCH1, DNECL, KIAA0325
Domain Architecture	No domain graphic available
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

DYHC_MOUSE
θ value	5.27518 (rank : 71)	NC score	0.028988 (rank : 52)
Query Neighborhood Hits	104	Target Neighborhood Hits	729	Shared Neighborhood Hits	22
SwissProt Accessions	Q9JHU4	Gene names	Dync1h1, Dnch1, Dnchc1
Domain Architecture
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

K2C8_HUMAN
θ value	5.27518 (rank : 72)	NC score	0.009808 (rank : 91)
Query Neighborhood Hits	104	Target Neighborhood Hits	593	Shared Neighborhood Hits	12
SwissProt Accessions	P05787, Q14099, Q14716, Q14717, Q53GJ0, Q6DHW5, Q6GMY0, Q96J60	Gene names	KRT8, CYK8
Domain Architecture
Description	Keratin, type II cytoskeletal 8 (Cytokeratin-8) (CK-8) (Keratin-8) (K8).

NFH_MOUSE
θ value	5.27518 (rank : 73)	NC score	0.010795 (rank : 89)
Query Neighborhood Hits	104	Target Neighborhood Hits	2247	Shared Neighborhood Hits	37
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

RAI14_MOUSE
θ value	5.27518 (rank : 74)	NC score	0.001906 (rank : 111)
Query Neighborhood Hits	104	Target Neighborhood Hits	1505	Shared Neighborhood Hits	24
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

RN146_MOUSE
θ value	5.27518 (rank : 75)	NC score	0.013951 (rank : 79)
Query Neighborhood Hits	104	Target Neighborhood Hits	161	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CZW6, Q3TF93	Gene names	Rnf146
Domain Architecture	No domain graphic available
Description	RING finger protein 146.

U2AFM_HUMAN
θ value	5.27518 (rank : 76)	NC score	0.014275 (rank : 78)
Query Neighborhood Hits	104	Target Neighborhood Hits	577	Shared Neighborhood Hits	15
SwissProt Accessions	Q15696	Gene names	ZRSR2, U2AF1-RS2, U2AF1L2, U2AF1RS2
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 2 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 2) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2) (NY-REN-20 antigen).

VPS53_HUMAN
θ value	5.27518 (rank : 77)	NC score	0.030727 (rank : 50)
Query Neighborhood Hits	104	Target Neighborhood Hits	107	Shared Neighborhood Hits	5
SwissProt Accessions	Q5VIR6, Q8WYW3, Q9BRR2, Q9BY02, Q9NV25	Gene names	VPS53
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associated protein 53.

VPS53_MOUSE
θ value	5.27518 (rank : 78)	NC score	0.030315 (rank : 51)
Query Neighborhood Hits	104	Target Neighborhood Hits	102	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CCB4, Q8C7U0, Q8CIA1, Q9CX82, Q9D6T7	Gene names	Vps53
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associated protein 53.

AP3B2_HUMAN
θ value	6.88961 (rank : 79)	NC score	0.010849 (rank : 88)
Query Neighborhood Hits	104	Target Neighborhood Hits	246	Shared Neighborhood Hits	13
SwissProt Accessions	Q13367, O14808	Gene names	AP3B2
Domain Architecture
Description	AP-3 complex subunit beta-2 (Adapter-related protein complex 3 beta-2 subunit) (Beta3B-adaptin) (Adaptor protein complex AP-3 beta-2 subunit) (AP-3 complex beta-2 subunit) (Clathrin assembly protein complex 3 beta-2 large chain) (Neuron-specific vesicle coat protein beta-NAP).

CABP4_HUMAN
θ value	6.88961 (rank : 80)	NC score	0.007132 (rank : 102)
Query Neighborhood Hits	104	Target Neighborhood Hits	250	Shared Neighborhood Hits	3
SwissProt Accessions	P57796, Q8N4Z2, Q8WWY5	Gene names	CABP4
Domain Architecture
Description	Calcium-binding protein 4 (CaBP4).

CABP4_MOUSE
θ value	6.88961 (rank : 81)	NC score	0.007827 (rank : 99)
Query Neighborhood Hits	104	Target Neighborhood Hits	212	Shared Neighborhood Hits	6
SwissProt Accessions	Q8VHC5	Gene names	Cabp4
Domain Architecture	No domain graphic available
Description	Calcium-binding protein 4 (CaBP4).

CASP_MOUSE
θ value	6.88961 (rank : 82)	NC score	0.008861 (rank : 95)
Query Neighborhood Hits	104	Target Neighborhood Hits	1152	Shared Neighborhood Hits	19
SwissProt Accessions	P70403, Q7TQJ4, Q91WN6	Gene names	Cutl1
Domain Architecture	No domain graphic available
Description	Protein CASP.

CS029_MOUSE
θ value	6.88961 (rank : 83)	NC score	0.019840 (rank : 69)
Query Neighborhood Hits	104	Target Neighborhood Hits	201	Shared Neighborhood Hits	8
SwissProt Accessions	Q9CS00	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf29 homolog.

FOXGA_HUMAN
θ value	6.88961 (rank : 84)	NC score	0.003483 (rank : 108)
Query Neighborhood Hits	104	Target Neighborhood Hits	132	Shared Neighborhood Hits	3
SwissProt Accessions	P55316	Gene names	FOXG1A, FKHL2
Domain Architecture
Description	Forkhead box protein G1A (Forkhead-related protein FKHL2) (Transcription factor BF-2) (Brain factor 2) (BF2) (HFK2).

K2C8_MOUSE
θ value	6.88961 (rank : 85)	NC score	0.008726 (rank : 96)
Query Neighborhood Hits	104	Target Neighborhood Hits	576	Shared Neighborhood Hits	11
SwissProt Accessions	P11679, Q3KQK5, Q3TGI1, Q3TJE1, Q3TKY7, Q61463, Q61518, Q61519	Gene names	Krt8, Krt2-8
Domain Architecture
Description	Keratin, type II cytoskeletal 8 (Cytokeratin-8) (CK-8) (Keratin-8) (K8) (Cytokeratin endo A).

OBSL1_HUMAN
θ value	6.88961 (rank : 86)	NC score	0.007403 (rank : 101)
Query Neighborhood Hits	104	Target Neighborhood Hits	354	Shared Neighborhood Hits	3
SwissProt Accessions	O75147, Q96IW3	Gene names	OBSL1, KIAA0657
Domain Architecture	No domain graphic available
Description	Obscurin-like protein 1 precursor.

R3HD1_HUMAN
θ value	6.88961 (rank : 87)	NC score	0.020439 (rank : 67)
Query Neighborhood Hits	104	Target Neighborhood Hits	203	Shared Neighborhood Hits	7
SwissProt Accessions	Q15032, Q8IW32	Gene names	R3HDM1, KIAA0029, R3HDM
Domain Architecture	No domain graphic available
Description	R3H domain-containing protein 1.

RAI1_MOUSE
θ value	6.88961 (rank : 88)	NC score	0.013143 (rank : 81)
Query Neighborhood Hits	104	Target Neighborhood Hits	344	Shared Neighborhood Hits	14
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

RBM16_HUMAN
θ value	6.88961 (rank : 89)	NC score	0.012912 (rank : 83)
Query Neighborhood Hits	104	Target Neighborhood Hits	300	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UPN6, Q5TBU6, Q9BQN8, Q9BX43	Gene names	RBM16, KIAA1116
Domain Architecture
Description	Putative RNA-binding protein 16 (RNA-binding motif protein 16).

RFC5_HUMAN
θ value	6.88961 (rank : 90)	NC score	0.043405 (rank : 37)
Query Neighborhood Hits	104	Target Neighborhood Hits	60	Shared Neighborhood Hits	16
SwissProt Accessions	P40937	Gene names	RFC5
Domain Architecture
Description	Replication factor C subunit 5 (Replication factor C 36 kDa subunit) (RF-C 36 kDa subunit) (RFC36) (Activator 1 36 kDa subunit) (A1 36 kDa subunit).

RFC5_MOUSE
θ value	6.88961 (rank : 91)	NC score	0.045790 (rank : 33)
Query Neighborhood Hits	104	Target Neighborhood Hits	58	Shared Neighborhood Hits	16
SwissProt Accessions	Q9D0F6	Gene names	Rfc5
Domain Architecture
Description	Replication factor C subunit 5 (Replication factor C 36 kDa subunit) (RF-C 36 kDa subunit) (RFC36) (Activator 1 36 kDa subunit) (A1 36 kDa subunit).

CM007_MOUSE
θ value	8.99809 (rank : 92)	NC score	0.009745 (rank : 92)
Query Neighborhood Hits	104	Target Neighborhood Hits	416	Shared Neighborhood Hits	10
SwissProt Accessions	Q8K2Y0, Q9CYU1, Q9D1Y0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf7 homolog.

CSMD2_HUMAN
θ value	8.99809 (rank : 93)	NC score	0.002457 (rank : 110)
Query Neighborhood Hits	104	Target Neighborhood Hits	188	Shared Neighborhood Hits	2
SwissProt Accessions	Q7Z408, Q5VT59, Q8N963, Q96Q03, Q9H4V7, Q9H4V8, Q9H4V9, Q9H4W0, Q9H4W1, Q9H4W2, Q9H4W3, Q9H4W4, Q9HCY5, Q9HCY6, Q9HCY7	Gene names	CSMD2, KIAA1884
Domain Architecture
Description	CUB and sushi domain-containing protein 2 (CUB and sushi multiple domains protein 2).

DCAK3_MOUSE
θ value	8.99809 (rank : 94)	NC score	0.000150 (rank : 112)
Query Neighborhood Hits	104	Target Neighborhood Hits	922	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BWQ5, Q1A748	Gene names	Dcamkl3
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase DCAMKL3 (EC 2.7.11.1) (Doublecortin- like and CAM kinase-like 3) (CLICK-I and II-related) (CLr).

GPR98_HUMAN
θ value	8.99809 (rank : 95)	NC score	0.005390 (rank : 105)
Query Neighborhood Hits	104	Target Neighborhood Hits	202	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WXG9, O75171, Q9H0X5, Q9UL61	Gene names	GPR98, KIAA0686, MASS1, VLGR1
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 98 precursor (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Very large G-protein coupled receptor 1) (Usher syndrome type-2C protein).

LC7L2_MOUSE
θ value	8.99809 (rank : 96)	NC score	0.011811 (rank : 84)
Query Neighborhood Hits	104	Target Neighborhood Hits	244	Shared Neighborhood Hits	11
SwissProt Accessions	Q7TNC4, Q99LM5, Q99PC3	Gene names	Luc7l2
Domain Architecture
Description	Putative RNA-binding protein Luc7-like 2 (CGI-74 homolog).

NIPBL_HUMAN
θ value	8.99809 (rank : 97)	NC score	0.028162 (rank : 56)
Query Neighborhood Hits	104	Target Neighborhood Hits	1311	Shared Neighborhood Hits	42
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

PHF20_MOUSE
θ value	8.99809 (rank : 98)	NC score	0.010610 (rank : 90)
Query Neighborhood Hits	104	Target Neighborhood Hits	513	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

PKHA6_MOUSE
θ value	8.99809 (rank : 99)	NC score	0.009481 (rank : 93)
Query Neighborhood Hits	104	Target Neighborhood Hits	591	Shared Neighborhood Hits	14
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

R51A1_MOUSE
θ value	8.99809 (rank : 100)	NC score	0.020986 (rank : 64)
Query Neighborhood Hits	104	Target Neighborhood Hits	164	Shared Neighborhood Hits	13
SwissProt Accessions	Q8C551, O55219, Q8BP36, Q99L94, Q9D0J0	Gene names	Rad51ap1
Domain Architecture	No domain graphic available
Description	RAD51-associated protein 1 (RAD51-interacting protein) (RAB22).

TEKT1_HUMAN
θ value	8.99809 (rank : 101)	NC score	0.005682 (rank : 104)
Query Neighborhood Hits	104	Target Neighborhood Hits	289	Shared Neighborhood Hits	5
SwissProt Accessions	Q969V4	Gene names	TEKT1
Domain Architecture
Description	Tektin-1.

U2AFL_HUMAN
θ value	8.99809 (rank : 102)	NC score	0.013061 (rank : 82)
Query Neighborhood Hits	104	Target Neighborhood Hits	503	Shared Neighborhood Hits	16
SwissProt Accessions	Q15695, Q13570	Gene names	ZRSR1, U2AF1-RS1, U2AF1L1, U2AF1RS1, U2AFBPL
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 1 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 1) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 1).

UBP31_HUMAN
θ value	8.99809 (rank : 103)	NC score	0.007881 (rank : 98)
Query Neighborhood Hits	104	Target Neighborhood Hits	293	Shared Neighborhood Hits	10
SwissProt Accessions	Q70CQ4, Q6AW97, Q6ZTC0, Q6ZTN2, Q9ULL7	Gene names	USP31, KIAA1203
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 31 (EC 3.1.2.15) (Ubiquitin thioesterase 31) (Ubiquitin-specific-processing protease 31) (Deubiquitinating enzyme 31).

XYLT2_MOUSE
θ value	8.99809 (rank : 104)	NC score	0.007779 (rank : 100)
Query Neighborhood Hits	104	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	Q9EPL0, Q5SUY1, Q8K060	Gene names	Xylt2
Domain Architecture	No domain graphic available
Description	Xylosyltransferase 2 (EC 2.4.2.26) (Xylosyltransferase II) (Peptide O- xylosyltransferase 2).

CX048_HUMAN
θ value	θ > 10 (rank : 105)	NC score	0.182511 (rank : 16)
Query Neighborhood Hits	104	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WUE5, Q9NWY8	Gene names	CXorf48
Domain Architecture	No domain graphic available
Description	Protein CXorf48 (Tumor antigen BJ-HCC-20).

RRP44_HUMAN
θ value	θ > 10 (rank : 106)	NC score	0.061791 (rank : 23)
Query Neighborhood Hits	104	Target Neighborhood Hits	35	Shared Neighborhood Hits	1
SwissProt Accessions	Q9Y2L1, Q5W0P7, Q5W0P8, Q658Z7, Q7Z481, Q8WWI2, Q9UG36	Gene names	DIS3, KIAA1008, RRP44
Domain Architecture
Description	Exosome complex exonuclease RRP44 (EC 3.1.13.-) (Ribosomal RNA- processing protein 44) (DIS3 protein homolog).

SPR2B_MOUSE
θ value	θ > 10 (rank : 107)	NC score	0.058842 (rank : 26)
Query Neighborhood Hits	104	Target Neighborhood Hits	51	Shared Neighborhood Hits	2
SwissProt Accessions	O70554, Q7TSB2	Gene names	Sprr2b
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2B.

SPR2D_MOUSE
θ value	θ > 10 (rank : 108)	NC score	0.061056 (rank : 24)
Query Neighborhood Hits	104	Target Neighborhood Hits	61	Shared Neighborhood Hits	3
SwissProt Accessions	O70555	Gene names	Sprr2d
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2D.

SPR2E_HUMAN
θ value	θ > 10 (rank : 109)	NC score	0.055057 (rank : 28)
Query Neighborhood Hits	104	Target Neighborhood Hits	32	Shared Neighborhood Hits	2
SwissProt Accessions	P22531, Q96RM2	Gene names	SPRR2E
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2E (SPR-2E) (Small proline-rich protein II) (SPR-II).

SPR2F_HUMAN
θ value	θ > 10 (rank : 110)	NC score	0.059029 (rank : 25)
Query Neighborhood Hits	104	Target Neighborhood Hits	33	Shared Neighborhood Hits	2
SwissProt Accessions	Q96RM1	Gene names	SPRR2F
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2F (SPR-2F).

SPR2G_MOUSE
θ value	θ > 10 (rank : 111)	NC score	0.058530 (rank : 27)
Query Neighborhood Hits	104	Target Neighborhood Hits	53	Shared Neighborhood Hits	2
SwissProt Accessions	O70558	Gene names	Sprr2g
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2G.

SPR2H_MOUSE
θ value	θ > 10 (rank : 112)	NC score	0.051631 (rank : 30)
Query Neighborhood Hits	104	Target Neighborhood Hits	82	Shared Neighborhood Hits	2
SwissProt Accessions	O70559	Gene names	Sprr2h
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2H.

Hits sorted by NC score

SMBP2_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	104	Target Neighborhood Hits	104	Shared Neighborhood Hits	104
SwissProt Accessions	P40694	Gene names	Ighmbp2, Smbp-2, Smbp2
Domain Architecture
Description	DNA-binding protein SMUBP-2 (EC 3.6.1.-) (ATP-dependent helicase IGHMBP2) (Immunoglobulin mu-binding protein 2) (SMUBP-2) (Cardiac transcription factor 1) (CATF1).

SMBP2_HUMAN
NC score	0.979198 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	104	Target Neighborhood Hits	107	Shared Neighborhood Hits	38
SwissProt Accessions	P38935, Q00443, Q14177	Gene names	IGHMBP2, SMBP2, SMUBP2
Domain Architecture
Description	DNA-binding protein SMUBP-2 (EC 3.6.1.-) (ATP-dependent helicase IGHMBP2) (Immunoglobulin mu-binding protein 2) (SMUBP-2) (Glial factor 1) (GF-1).

RENT1_HUMAN
NC score	0.816595 (rank : 3)	θ value	1.15895e-47 (rank : 3)
Query Neighborhood Hits	104	Target Neighborhood Hits	51	Shared Neighborhood Hits	15
SwissProt Accessions	Q92900, O00239, O43343, Q86Z25, Q92842	Gene names	UPF1, KIAA0221, RENT1
Domain Architecture
Description	Regulator of nonsense transcripts 1 (EC 3.6.1.-) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up- frameshift suppressor 1 homolog) (hUpf1).

RENT1_MOUSE
NC score	0.816413 (rank : 4)	θ value	1.51363e-47 (rank : 4)
Query Neighborhood Hits	104	Target Neighborhood Hits	54	Shared Neighborhood Hits	15
SwissProt Accessions	Q9EPU0, Q99PR4	Gene names	Upf1, Rent1
Domain Architecture
Description	Regulator of nonsense transcripts 1 (EC 3.6.1.-) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up- frameshift suppressor 1 homolog) (mUpf1).

PR285_HUMAN
NC score	0.714336 (rank : 5)	θ value	8.3442e-30 (rank : 6)
Query Neighborhood Hits	104	Target Neighborhood Hits	63	Shared Neighborhood Hits	18
SwissProt Accessions	Q9BYK8, Q3C2G2, Q4VXQ1, Q8TEF3, Q96ND3, Q9C094	Gene names	PRIC285, KIAA1769
Domain Architecture
Description	Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein (EC 3.6.1.-) (ATP-dependent helicase PRIC285) (PPAR-alpha- interacting complex protein 285) (PPAR-gamma DBD-interacting protein 1) (PDIP1).

MOV10_MOUSE
NC score	0.713571 (rank : 6)	θ value	2.35151e-24 (rank : 8)
Query Neighborhood Hits	104	Target Neighborhood Hits	39	Shared Neighborhood Hits	20
SwissProt Accessions	P23249, Q9DC64	Gene names	Mov10, Gb110
Domain Architecture
Description	Putative helicase MOV-10 (EC 3.6.1.-) (Moloney leukemia virus 10 protein).

M10L1_HUMAN
NC score	0.713428 (rank : 7)	θ value	4.14116e-29 (rank : 7)
Query Neighborhood Hits	104	Target Neighborhood Hits	36	Shared Neighborhood Hits	19
SwissProt Accessions	Q9BXT6, Q5TGD5, Q8NBD4, Q9NXW3, Q9UFB3, Q9UGX9	Gene names	MOV10L1
Domain Architecture
Description	Putative helicase Mov10l1 (EC 3.6.1.-) (Moloney leukemia virus 10-like protein 1) (MOV10-like 1).

SETX_HUMAN
NC score	0.712045 (rank : 8)	θ value	9.52487e-34 (rank : 5)
Query Neighborhood Hits	104	Target Neighborhood Hits	368	Shared Neighborhood Hits	28
SwissProt Accessions	Q7Z333, O75120, Q3KQX4, Q68DW5, Q6AZD7, Q7Z3J6, Q8WX33, Q9H9D1, Q9NVP9	Gene names	SETX, ALS4, KIAA0625, SCAR1
Domain Architecture
Description	Probable helicase senataxin (EC 3.6.1.-) (SEN1 homolog).

MOV10_HUMAN
NC score	0.711502 (rank : 9)	θ value	1.5242e-23 (rank : 9)
Query Neighborhood Hits	104	Target Neighborhood Hits	46	Shared Neighborhood Hits	20
SwissProt Accessions	Q9HCE1, Q8TEF0, Q9BSY3, Q9BUJ9	Gene names	MOV10, KIAA1631
Domain Architecture
Description	Putative helicase MOV-10 (EC 3.6.1.-) (Moloney leukemia virus 10 protein).

M10L1_MOUSE
NC score	0.695654 (rank : 10)	θ value	2.69047e-20 (rank : 10)
Query Neighborhood Hits	104	Target Neighborhood Hits	59	Shared Neighborhood Hits	20
SwissProt Accessions	Q99MV5, Q7TPA9, Q8C3W0, Q924C2	Gene names	Mov10l1, Champ
Domain Architecture
Description	Putative helicase Mov10l1 (EC 3.6.1.-) (Moloney leukemia virus 10-like protein 1) (MOV10-like 1) (Cardiac helicase activated by MEF2 protein) (Cardiac-specific RNA helicase).

HELZ_HUMAN
NC score	0.625801 (rank : 11)	θ value	4.16044e-13 (rank : 12)
Query Neighborhood Hits	104	Target Neighborhood Hits	198	Shared Neighborhood Hits	22
SwissProt Accessions	P42694	Gene names	HELZ, KIAA0054
Domain Architecture	No domain graphic available
Description	Probable helicase with zinc-finger domain (EC 3.6.1.-).

AQR_MOUSE
NC score	0.486195 (rank : 12)	θ value	5.62301e-10 (rank : 15)
Query Neighborhood Hits	104	Target Neighborhood Hits	62	Shared Neighborhood Hits	17
SwissProt Accessions	Q8CFQ3, P97871, Q3U9N1, Q3ULE8, Q80TX8	Gene names	Aqr, Kiaa0560
Domain Architecture	No domain graphic available
Description	Intron-binding protein aquarius.

AQR_HUMAN
NC score	0.483230 (rank : 13)	θ value	5.62301e-10 (rank : 14)
Query Neighborhood Hits	104	Target Neighborhood Hits	88	Shared Neighborhood Hits	17
SwissProt Accessions	O60306, Q2YDX9, Q6IRU8, Q6PIC8	Gene names	AQR, KIAA0560
Domain Architecture	No domain graphic available
Description	Intron-binding protein aquarius (Intron-binding protein of 160 kDa) (IBP160).

ZNFX1_MOUSE
NC score	0.476346 (rank : 14)	θ value	2.20605e-14 (rank : 11)
Query Neighborhood Hits	104	Target Neighborhood Hits	407	Shared Neighborhood Hits	20
SwissProt Accessions	Q8R151, Q3U016, Q3UD71, Q3UEZ0	Gene names	ZNFX1
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

ZNFX1_HUMAN
NC score	0.472511 (rank : 15)	θ value	5.43371e-13 (rank : 13)
Query Neighborhood Hits	104	Target Neighborhood Hits	308	Shared Neighborhood Hits	22
SwissProt Accessions	Q9P2E3, Q9BQM7, Q9BQM8, Q9H8C1, Q9H9S2, Q9NUM1, Q9NWW1	Gene names	ZNFX1, KIAA1404
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

CX048_HUMAN
NC score	0.182511 (rank : 16)	θ value	θ > 10 (rank : 105)
Query Neighborhood Hits	104	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WUE5, Q9NWY8	Gene names	CXorf48
Domain Architecture	No domain graphic available
Description	Protein CXorf48 (Tumor antigen BJ-HCC-20).

NKRF_MOUSE
NC score	0.118952 (rank : 17)	θ value	0.00228821 (rank : 16)
Query Neighborhood Hits	104	Target Neighborhood Hits	67	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BY02, Q8BJU5, Q9CRL2	Gene names	Nkrf, Nrf
Domain Architecture
Description	NF-kappa-B-repressing factor (NFKB-repressing factor) (Transcription factor NRF).

NKRF_HUMAN
NC score	0.110040 (rank : 18)	θ value	0.0252991 (rank : 18)
Query Neighborhood Hits	104	Target Neighborhood Hits	57	Shared Neighborhood Hits	4
SwissProt Accessions	O15226, Q9UJ91	Gene names	NKRF, ITBA4, NRF
Domain Architecture
Description	NF-kappa-B-repressing factor (NFKB-repressing factor) (Transcription factor NRF) (ITBA4 protein).

TRP13_HUMAN
NC score	0.074802 (rank : 19)	θ value	0.125558 (rank : 25)
Query Neighborhood Hits	104	Target Neighborhood Hits	81	Shared Neighborhood Hits	13
SwissProt Accessions	Q15645, O15324	Gene names	TRIP13
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 13 (Thyroid hormone receptor interactor 13) (Trip-13) (Human papillomavirus type 16 E1 protein- binding protein) (HPV16 E1 protein-binding protein) (16E1-BP).

DHX57_MOUSE
NC score	0.069688 (rank : 20)	θ value	0.0431538 (rank : 20)
Query Neighborhood Hits	104	Target Neighborhood Hits	125	Shared Neighborhood Hits	13
SwissProt Accessions	Q6P5D3, Q3TS93, Q6NZK4, Q6P1B4, Q8BI63, Q8BIA2, Q8R360	Gene names	Dhx57
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX57 (EC 3.6.1.-) (DEAH box protein 57).

TRP13_MOUSE
NC score	0.069472 (rank : 21)	θ value	0.279714 (rank : 27)
Query Neighborhood Hits	104	Target Neighborhood Hits	81	Shared Neighborhood Hits	13
SwissProt Accessions	Q3UA06, Q3UQG6, Q9CWW8	Gene names	Trip13
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 13 (Thyroid hormone receptor interactor 13) (Trip-13).

DHX57_HUMAN
NC score	0.067839 (rank : 22)	θ value	0.0736092 (rank : 21)
Query Neighborhood Hits	104	Target Neighborhood Hits	109	Shared Neighborhood Hits	13
SwissProt Accessions	Q6P158, Q53SI4, Q6P9G1, Q7Z6H3, Q8NG17, Q96M33	Gene names	DHX57
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX57 (EC 3.6.1.-) (DEAH box protein 57).

RRP44_HUMAN
NC score	0.061791 (rank : 23)	θ value	θ > 10 (rank : 106)
Query Neighborhood Hits	104	Target Neighborhood Hits	35	Shared Neighborhood Hits	1
SwissProt Accessions	Q9Y2L1, Q5W0P7, Q5W0P8, Q658Z7, Q7Z481, Q8WWI2, Q9UG36	Gene names	DIS3, KIAA1008, RRP44
Domain Architecture
Description	Exosome complex exonuclease RRP44 (EC 3.1.13.-) (Ribosomal RNA- processing protein 44) (DIS3 protein homolog).

SPR2D_MOUSE
NC score	0.061056 (rank : 24)	θ value	θ > 10 (rank : 108)
Query Neighborhood Hits	104	Target Neighborhood Hits	61	Shared Neighborhood Hits	3
SwissProt Accessions	O70555	Gene names	Sprr2d
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2D.

SPR2F_HUMAN
NC score	0.059029 (rank : 25)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	104	Target Neighborhood Hits	33	Shared Neighborhood Hits	2
SwissProt Accessions	Q96RM1	Gene names	SPRR2F
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2F (SPR-2F).

SPR2B_MOUSE
NC score	0.058842 (rank : 26)	θ value	θ > 10 (rank : 107)
Query Neighborhood Hits	104	Target Neighborhood Hits	51	Shared Neighborhood Hits	2
SwissProt Accessions	O70554, Q7TSB2	Gene names	Sprr2b
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2B.

SPR2G_MOUSE
NC score	0.058530 (rank : 27)	θ value	θ > 10 (rank : 111)
Query Neighborhood Hits	104	Target Neighborhood Hits	53	Shared Neighborhood Hits	2
SwissProt Accessions	O70558	Gene names	Sprr2g
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2G.

SPR2E_HUMAN
NC score	0.055057 (rank : 28)	θ value	θ > 10 (rank : 109)
Query Neighborhood Hits	104	Target Neighborhood Hits	32	Shared Neighborhood Hits	2
SwissProt Accessions	P22531, Q96RM2	Gene names	SPRR2E
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2E (SPR-2E) (Small proline-rich protein II) (SPR-II).

DHX36_MOUSE
NC score	0.054623 (rank : 29)	θ value	0.365318 (rank : 28)
Query Neighborhood Hits	104	Target Neighborhood Hits	114	Shared Neighborhood Hits	11
SwissProt Accessions	Q8VHK9, Q6ZPP7, Q9CSE8	Gene names	Dhx36, Ddx36, Kiaa1488, Mlel1
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX36 (EC 3.6.1.-) (DEAH box protein 36) (MLE-like protein 1) (RNA helicase associated with AU-rich element ARE).

SPR2H_MOUSE
NC score	0.051631 (rank : 30)	θ value	θ > 10 (rank : 112)
Query Neighborhood Hits	104	Target Neighborhood Hits	82	Shared Neighborhood Hits	2
SwissProt Accessions	O70559	Gene names	Sprr2h
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2H.

DHX9_HUMAN
NC score	0.048532 (rank : 31)	θ value	1.81305 (rank : 47)
Query Neighborhood Hits	104	Target Neighborhood Hits	62	Shared Neighborhood Hits	9
SwissProt Accessions	Q08211, Q5VY62, Q6PD69, Q99556	Gene names	DHX9, DDX9, NDH2
Domain Architecture
Description	ATP-dependent RNA helicase A (EC 3.6.1.-) (Nuclear DNA helicase II) (NDH II) (DEAH box protein 9).

PEX6_MOUSE
NC score	0.048294 (rank : 32)	θ value	0.0252991 (rank : 19)
Query Neighborhood Hits	104	Target Neighborhood Hits	94	Shared Neighborhood Hits	12
SwissProt Accessions	Q99LC9, Q6YNQ9	Gene names	Pex6
Domain Architecture	No domain graphic available
Description	Peroxisome assembly factor 2 (PAF-2) (Peroxisomal-type ATPase 1) (Peroxin-6) (Peroxisomal biogenesis factor 6).

RFC5_MOUSE
NC score	0.045790 (rank : 33)	θ value	6.88961 (rank : 91)
Query Neighborhood Hits	104	Target Neighborhood Hits	58	Shared Neighborhood Hits	16
SwissProt Accessions	Q9D0F6	Gene names	Rfc5
Domain Architecture
Description	Replication factor C subunit 5 (Replication factor C 36 kDa subunit) (RF-C 36 kDa subunit) (RFC36) (Activator 1 36 kDa subunit) (A1 36 kDa subunit).

PEO1_HUMAN
NC score	0.045748 (rank : 34)	θ value	2.36792 (rank : 53)
Query Neighborhood Hits	104	Target Neighborhood Hits	18	Shared Neighborhood Hits	8
SwissProt Accessions	Q96RR1, Q6MZX2, Q96RR0	Gene names	PEO1, C10orf2
Domain Architecture	No domain graphic available
Description	Twinkle protein, mitochondrial precursor (EC 3.6.1.-) (T7 gp4-like protein with intramitochondrial nucleoid localization) (T7-like mitochondrial DNA helicase) (Progressive external ophthalmoplegia 1 protein).

DHX16_HUMAN
NC score	0.044471 (rank : 35)	θ value	0.62314 (rank : 32)
Query Neighborhood Hits	104	Target Neighborhood Hits	356	Shared Neighborhood Hits	19
SwissProt Accessions	O60231, O60322, Q969X7, Q96QC1	Gene names	DHX16, DBP2, DDX16, KIAA0577
Domain Architecture
Description	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 (EC 3.6.1.-) (DEAH-box protein 16) (ATP-dependent RNA helicase #3).

PEO1_MOUSE
NC score	0.043944 (rank : 36)	θ value	3.0926 (rank : 60)
Query Neighborhood Hits	104	Target Neighborhood Hits	27	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CIW5, Q8K1Z1	Gene names	Peo1
Domain Architecture	No domain graphic available
Description	Twinkle protein, mitochondrial precursor (EC 3.6.1.-) (T7 gp4-like protein with intramitochondrial nucleoid localization) (T7-like mitochondrial DNA helicase) (Progressive external ophthalmoplegia 1 protein homolog).

RFC5_HUMAN
NC score	0.043405 (rank : 37)	θ value	6.88961 (rank : 90)
Query Neighborhood Hits	104	Target Neighborhood Hits	60	Shared Neighborhood Hits	16
SwissProt Accessions	P40937	Gene names	RFC5
Domain Architecture
Description	Replication factor C subunit 5 (Replication factor C 36 kDa subunit) (RF-C 36 kDa subunit) (RFC36) (Activator 1 36 kDa subunit) (A1 36 kDa subunit).

DHX8_HUMAN
NC score	0.043088 (rank : 38)	θ value	1.81305 (rank : 46)
Query Neighborhood Hits	104	Target Neighborhood Hits	86	Shared Neighborhood Hits	11
SwissProt Accessions	Q14562	Gene names	DHX8, DDX8
Domain Architecture
Description	ATP-dependent RNA helicase DHX8 (EC 3.6.1.-) (DEAH box protein 8) (RNA helicase HRH1).

DHX37_HUMAN
NC score	0.042864 (rank : 39)	θ value	3.0926 (rank : 55)
Query Neighborhood Hits	104	Target Neighborhood Hits	133	Shared Neighborhood Hits	13
SwissProt Accessions	Q8IY37, Q9BUI7, Q9P211	Gene names	DHX37, DDX37, KIAA1517
Domain Architecture
Description	Probable ATP-dependent RNA helicase DHX37 (EC 3.6.1.-) (DEAH box protein 37).

SC24D_HUMAN
NC score	0.041734 (rank : 40)	θ value	0.0736092 (rank : 23)
Query Neighborhood Hits	104	Target Neighborhood Hits	173	Shared Neighborhood Hits	5
SwissProt Accessions	O94855	Gene names	SEC24D, KIAA0755
Domain Architecture
Description	Protein transport protein Sec24D (SEC24-related protein D).

PEX6_HUMAN
NC score	0.041602 (rank : 41)	θ value	1.06291 (rank : 40)
Query Neighborhood Hits	104	Target Neighborhood Hits	99	Shared Neighborhood Hits	14
SwissProt Accessions	Q13608, Q8WYQ2, Q99476	Gene names	PEX6, PXAAA1
Domain Architecture
Description	Peroxisome assembly factor 2 (PAF-2) (Peroxisomal-type ATPase 1) (Peroxin-6) (Peroxisomal biogenesis factor 6).

FILA_HUMAN
NC score	0.037737 (rank : 42)	θ value	0.813845 (rank : 35)
Query Neighborhood Hits	104	Target Neighborhood Hits	685	Shared Neighborhood Hits	28
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

NCOR2_MOUSE
NC score	0.037713 (rank : 43)	θ value	0.365318 (rank : 29)
Query Neighborhood Hits	104	Target Neighborhood Hits	790	Shared Neighborhood Hits	23
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

HORN_HUMAN
NC score	0.036999 (rank : 44)	θ value	0.279714 (rank : 26)
Query Neighborhood Hits	104	Target Neighborhood Hits	206	Shared Neighborhood Hits	11
SwissProt Accessions	Q86YZ3	Gene names	HRNR, S100A18
Domain Architecture	No domain graphic available
Description	Hornerin.

K1683_HUMAN
NC score	0.036726 (rank : 45)	θ value	0.62314 (rank : 33)
Query Neighborhood Hits	104	Target Neighborhood Hits	240	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H0B3, Q8N4G8, Q96M14, Q9C0I0	Gene names	KIAA1683
Domain Architecture	No domain graphic available
Description	Protein KIAA1683.

PKCB1_HUMAN
NC score	0.036130 (rank : 46)	θ value	0.125558 (rank : 24)
Query Neighborhood Hits	104	Target Neighborhood Hits	488	Shared Neighborhood Hits	14
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

NCOR2_HUMAN
NC score	0.034861 (rank : 47)	θ value	1.06291 (rank : 38)
Query Neighborhood Hits	104	Target Neighborhood Hits	870	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

ELOA2_HUMAN
NC score	0.033950 (rank : 48)	θ value	0.47712 (rank : 30)
Query Neighborhood Hits	104	Target Neighborhood Hits	165	Shared Neighborhood Hits	9
SwissProt Accessions	Q8IYF1, Q9P2V9	Gene names	TCEB3B, TCEB3L
Domain Architecture
Description	RNA polymerase II transcription factor SIII subunit A2 (Elongin-A2) (EloA2) (Transcription elongation factor B polypeptide 3B).

PHAR2_HUMAN
NC score	0.032023 (rank : 49)	θ value	0.813845 (rank : 37)
Query Neighborhood Hits	104	Target Neighborhood Hits	208	Shared Neighborhood Hits	10
SwissProt Accessions	O75167, Q68DM2	Gene names	PHACTR2, C6orf56, KIAA0680
Domain Architecture	No domain graphic available
Description	Phosphatase and actin regulator 2.

VPS53_HUMAN
NC score	0.030727 (rank : 50)	θ value	5.27518 (rank : 77)
Query Neighborhood Hits	104	Target Neighborhood Hits	107	Shared Neighborhood Hits	5
SwissProt Accessions	Q5VIR6, Q8WYW3, Q9BRR2, Q9BY02, Q9NV25	Gene names	VPS53
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associated protein 53.

VPS53_MOUSE
NC score	0.030315 (rank : 51)	θ value	5.27518 (rank : 78)
Query Neighborhood Hits	104	Target Neighborhood Hits	102	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CCB4, Q8C7U0, Q8CIA1, Q9CX82, Q9D6T7	Gene names	Vps53
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associated protein 53.

DYHC_MOUSE
NC score	0.028988 (rank : 52)	θ value	5.27518 (rank : 71)
Query Neighborhood Hits	104	Target Neighborhood Hits	729	Shared Neighborhood Hits	22
SwissProt Accessions	Q9JHU4	Gene names	Dync1h1, Dnch1, Dnchc1
Domain Architecture
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

DYHC_HUMAN
NC score	0.028913 (rank : 53)	θ value	5.27518 (rank : 70)
Query Neighborhood Hits	104	Target Neighborhood Hits	733	Shared Neighborhood Hits	21
SwissProt Accessions	Q14204, Q6DKQ7, Q8WU28, Q92814, Q9Y4G5	Gene names	DYNC1H1, DNCH1, DNECL, KIAA0325
Domain Architecture	No domain graphic available
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

AFF4_HUMAN
NC score	0.028487 (rank : 54)	θ value	1.38821 (rank : 41)
Query Neighborhood Hits	104	Target Neighborhood Hits	611	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

CCNT2_HUMAN
NC score	0.028419 (rank : 55)	θ value	0.62314 (rank : 31)
Query Neighborhood Hits	104	Target Neighborhood Hits	84	Shared Neighborhood Hits	5
SwissProt Accessions	O60583, O60582, Q5I1Y0	Gene names	CCNT2
Domain Architecture
Description	Cyclin-T2 (CycT2).

NIPBL_HUMAN
NC score	0.028162 (rank : 56)	θ value	8.99809 (rank : 97)
Query Neighborhood Hits	104	Target Neighborhood Hits	1311	Shared Neighborhood Hits	42
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

SYN1_HUMAN
NC score	0.027352 (rank : 57)	θ value	1.38821 (rank : 45)
Query Neighborhood Hits	104	Target Neighborhood Hits	419	Shared Neighborhood Hits	14
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

ABRA_HUMAN
NC score	0.026221 (rank : 58)	θ value	2.36792 (rank : 49)
Query Neighborhood Hits	104	Target Neighborhood Hits	52	Shared Neighborhood Hits	5
SwissProt Accessions	Q8N0Z2	Gene names	ABRA
Domain Architecture	No domain graphic available
Description	Actin-binding Rho-activating protein (Striated muscle activator of Rho-dependent signaling) (STARS).

ASPX_HUMAN
NC score	0.025890 (rank : 59)	θ value	4.03905 (rank : 65)
Query Neighborhood Hits	104	Target Neighborhood Hits	148	Shared Neighborhood Hits	9
SwissProt Accessions	P26436	Gene names	ACRV1
Domain Architecture
Description	Acrosomal protein SP-10 precursor (Acrosomal vesicle protein 1).

NPBL_MOUSE
NC score	0.024734 (rank : 60)	θ value	3.0926 (rank : 59)
Query Neighborhood Hits	104	Target Neighborhood Hits	1041	Shared Neighborhood Hits	35
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

SYN1_MOUSE
NC score	0.024015 (rank : 61)	θ value	3.0926 (rank : 62)
Query Neighborhood Hits	104	Target Neighborhood Hits	363	Shared Neighborhood Hits	13
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

CUTL2_HUMAN
NC score	0.023854 (rank : 62)	θ value	2.36792 (rank : 52)
Query Neighborhood Hits	104	Target Neighborhood Hits	906	Shared Neighborhood Hits	21
SwissProt Accessions	O14529	Gene names	CUTL2, KIAA0293
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

BSN_MOUSE
NC score	0.021873 (rank : 63)	θ value	2.36792 (rank : 50)
Query Neighborhood Hits	104	Target Neighborhood Hits	2057	Shared Neighborhood Hits	35
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

R51A1_MOUSE
NC score	0.020986 (rank : 64)	θ value	8.99809 (rank : 100)
Query Neighborhood Hits	104	Target Neighborhood Hits	164	Shared Neighborhood Hits	13
SwissProt Accessions	Q8C551, O55219, Q8BP36, Q99L94, Q9D0J0	Gene names	Rad51ap1
Domain Architecture	No domain graphic available
Description	RAD51-associated protein 1 (RAD51-interacting protein) (RAB22).

GRIN1_HUMAN
NC score	0.020950 (rank : 65)	θ value	3.0926 (rank : 56)
Query Neighborhood Hits	104	Target Neighborhood Hits	681	Shared Neighborhood Hits	20
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

TGON2_HUMAN
NC score	0.020831 (rank : 66)	θ value	3.0926 (rank : 63)
Query Neighborhood Hits	104	Target Neighborhood Hits	1037	Shared Neighborhood Hits	33
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

R3HD1_HUMAN
NC score	0.020439 (rank : 67)	θ value	6.88961 (rank : 87)
Query Neighborhood Hits	104	Target Neighborhood Hits	203	Shared Neighborhood Hits	7
SwissProt Accessions	Q15032, Q8IW32	Gene names	R3HDM1, KIAA0029, R3HDM
Domain Architecture	No domain graphic available
Description	R3H domain-containing protein 1.

R3HD2_MOUSE
NC score	0.020427 (rank : 68)	θ value	4.03905 (rank : 68)
Query Neighborhood Hits	104	Target Neighborhood Hits	397	Shared Neighborhood Hits	10
SwissProt Accessions	Q80TM6, Q80YB1, Q8BLS5, Q9CW50	Gene names	R3hdm2, Kiaa1002
Domain Architecture
Description	R3H domain-containing protein 2.

CS029_MOUSE
NC score	0.019840 (rank : 69)	θ value	6.88961 (rank : 83)
Query Neighborhood Hits	104	Target Neighborhood Hits	201	Shared Neighborhood Hits	8
SwissProt Accessions	Q9CS00	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf29 homolog.

RA51B_HUMAN
NC score	0.018939 (rank : 70)	θ value	3.0926 (rank : 61)
Query Neighborhood Hits	104	Target Neighborhood Hits	28	Shared Neighborhood Hits	6
SwissProt Accessions	O15315, O60914, O75210, Q3Y4F8, Q86SY3, Q86SY4, Q86TR0, Q86U92, Q86U93, Q86U94, Q8N6H4, Q9UPL5	Gene names	RAD51L1, RAD51B, REC2
Domain Architecture
Description	DNA repair protein RAD51 homolog 2 (R51H2) (RAD51-like protein 1) (Rad51B).

KTNA1_MOUSE
NC score	0.018451 (rank : 71)	θ value	3.0926 (rank : 57)
Query Neighborhood Hits	104	Target Neighborhood Hits	123	Shared Neighborhood Hits	7
SwissProt Accessions	Q9WV86	Gene names	Katna1
Domain Architecture	No domain graphic available
Description	Katanin p60 ATPase-containing subunit A1 (EC 3.6.4.3) (Katanin p60 subunit A1) (p60 katanin) (Lipotransin).

TOP2A_HUMAN
NC score	0.017543 (rank : 72)	θ value	1.81305 (rank : 48)
Query Neighborhood Hits	104	Target Neighborhood Hits	135	Shared Neighborhood Hits	8
SwissProt Accessions	P11388, Q71UN1, Q9HB24, Q9HB25, Q9HB26, Q9UP44, Q9UQP9	Gene names	TOP2A, TOP2
Domain Architecture
Description	DNA topoisomerase 2-alpha (EC 5.99.1.3) (DNA topoisomerase II, alpha isozyme).

RUSC2_MOUSE
NC score	0.017061 (rank : 73)	θ value	4.03905 (rank : 69)
Query Neighborhood Hits	104	Target Neighborhood Hits	305	Shared Neighborhood Hits	12
SwissProt Accessions	Q80U22, Q8R1D6	Gene names	Rusc2, Kiaa0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

CUTL1_HUMAN
NC score	0.016910 (rank : 74)	θ value	0.813845 (rank : 34)
Query Neighborhood Hits	104	Target Neighborhood Hits	1574	Shared Neighborhood Hits	28
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

CTND2_MOUSE
NC score	0.015361 (rank : 75)	θ value	1.38821 (rank : 42)
Query Neighborhood Hits	104	Target Neighborhood Hits	227	Shared Neighborhood Hits	10
SwissProt Accessions	O35927	Gene names	Ctnnd2, Catnd2, Nprap
Domain Architecture
Description	Catenin delta-2 (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin).

TMC2_HUMAN
NC score	0.015320 (rank : 76)	θ value	3.0926 (rank : 64)
Query Neighborhood Hits	104	Target Neighborhood Hits	149	Shared Neighborhood Hits	8
SwissProt Accessions	Q8TDI7, Q5JXT0, Q5JXT1, Q6UWW4, Q6ZS41, Q8N9F3, Q9BYN2, Q9BYN3, Q9BYN4, Q9BYN5	Gene names	TMC2
Domain Architecture	No domain graphic available
Description	Transmembrane cochlear-expressed protein 2.

MSH6_MOUSE
NC score	0.014391 (rank : 77)	θ value	3.0926 (rank : 58)
Query Neighborhood Hits	104	Target Neighborhood Hits	55	Shared Neighborhood Hits	4
SwissProt Accessions	P54276, O54710	Gene names	Msh6, Gtmbp
Domain Architecture
Description	DNA mismatch repair protein MSH6 (MutS-alpha 160 kDa subunit) (G/T mismatch-binding protein) (GTBP) (GTMBP) (p160).

U2AFM_HUMAN
NC score	0.014275 (rank : 78)	θ value	5.27518 (rank : 76)
Query Neighborhood Hits	104	Target Neighborhood Hits	577	Shared Neighborhood Hits	15
SwissProt Accessions	Q15696	Gene names	ZRSR2, U2AF1-RS2, U2AF1L2, U2AF1RS2
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 2 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 2) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2) (NY-REN-20 antigen).

RN146_MOUSE
NC score	0.013951 (rank : 79)	θ value	5.27518 (rank : 75)
Query Neighborhood Hits	104	Target Neighborhood Hits	161	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CZW6, Q3TF93	Gene names	Rnf146
Domain Architecture	No domain graphic available
Description	RING finger protein 146.

LMO6_HUMAN
NC score	0.013218 (rank : 80)	θ value	0.813845 (rank : 36)
Query Neighborhood Hits	104	Target Neighborhood Hits	337	Shared Neighborhood Hits	3
SwissProt Accessions	O43900, O76007	Gene names	LMO6
Domain Architecture
Description	LIM domain only protein 6 (Triple LIM domain protein 6).

RAI1_MOUSE
NC score	0.013143 (rank : 81)	θ value	6.88961 (rank : 88)
Query Neighborhood Hits	104	Target Neighborhood Hits	344	Shared Neighborhood Hits	14
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

U2AFL_HUMAN
NC score	0.013061 (rank : 82)	θ value	8.99809 (rank : 102)
Query Neighborhood Hits	104	Target Neighborhood Hits	503	Shared Neighborhood Hits	16
SwissProt Accessions	Q15695, Q13570	Gene names	ZRSR1, U2AF1-RS1, U2AF1L1, U2AF1RS1, U2AFBPL
Domain Architecture
Description	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 1 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 1) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 1).

RBM16_HUMAN
NC score	0.012912 (rank : 83)	θ value	6.88961 (rank : 89)
Query Neighborhood Hits	104	Target Neighborhood Hits	300	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UPN6, Q5TBU6, Q9BQN8, Q9BX43	Gene names	RBM16, KIAA1116
Domain Architecture
Description	Putative RNA-binding protein 16 (RNA-binding motif protein 16).

LC7L2_MOUSE
NC score	0.011811 (rank : 84)	θ value	8.99809 (rank : 96)
Query Neighborhood Hits	104	Target Neighborhood Hits	244	Shared Neighborhood Hits	11
SwissProt Accessions	Q7TNC4, Q99LM5, Q99PC3	Gene names	Luc7l2
Domain Architecture
Description	Putative RNA-binding protein Luc7-like 2 (CGI-74 homolog).

MAST4_HUMAN
NC score	0.011767 (rank : 85)	θ value	0.0736092 (rank : 22)
Query Neighborhood Hits	104	Target Neighborhood Hits	1804	Shared Neighborhood Hits	34
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

ABCF2_MOUSE
NC score	0.011336 (rank : 86)	θ value	3.0926 (rank : 54)
Query Neighborhood Hits	104	Target Neighborhood Hits	111	Shared Neighborhood Hits	2
SwissProt Accessions	Q99LE6, Q3UA24, Q8C1S5, Q9JL48	Gene names	Abcf2
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 2.

CLMN_HUMAN
NC score	0.011032 (rank : 87)	θ value	2.36792 (rank : 51)
Query Neighborhood Hits	104	Target Neighborhood Hits	205	Shared Neighborhood Hits	7
SwissProt Accessions	Q96JQ2, Q9H713, Q9HA23, Q9HA57, Q9UFP4, Q9ULN2	Gene names	CLMN, KIAA1188
Domain Architecture
Description	Calmin.

AP3B2_HUMAN
NC score	0.010849 (rank : 88)	θ value	6.88961 (rank : 79)
Query Neighborhood Hits	104	Target Neighborhood Hits	246	Shared Neighborhood Hits	13
SwissProt Accessions	Q13367, O14808	Gene names	AP3B2
Domain Architecture
Description	AP-3 complex subunit beta-2 (Adapter-related protein complex 3 beta-2 subunit) (Beta3B-adaptin) (Adaptor protein complex AP-3 beta-2 subunit) (AP-3 complex beta-2 subunit) (Clathrin assembly protein complex 3 beta-2 large chain) (Neuron-specific vesicle coat protein beta-NAP).

NFH_MOUSE
NC score	0.010795 (rank : 89)	θ value	5.27518 (rank : 73)
Query Neighborhood Hits	104	Target Neighborhood Hits	2247	Shared Neighborhood Hits	37
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

PHF20_MOUSE
NC score	0.010610 (rank : 90)	θ value	8.99809 (rank : 98)
Query Neighborhood Hits	104	Target Neighborhood Hits	513	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

K2C8_HUMAN
NC score	0.009808 (rank : 91)	θ value	5.27518 (rank : 72)
Query Neighborhood Hits	104	Target Neighborhood Hits	593	Shared Neighborhood Hits	12
SwissProt Accessions	P05787, Q14099, Q14716, Q14717, Q53GJ0, Q6DHW5, Q6GMY0, Q96J60	Gene names	KRT8, CYK8
Domain Architecture
Description	Keratin, type II cytoskeletal 8 (Cytokeratin-8) (CK-8) (Keratin-8) (K8).

CM007_MOUSE
NC score	0.009745 (rank : 92)	θ value	8.99809 (rank : 92)
Query Neighborhood Hits	104	Target Neighborhood Hits	416	Shared Neighborhood Hits	10
SwissProt Accessions	Q8K2Y0, Q9CYU1, Q9D1Y0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf7 homolog.

PKHA6_MOUSE
NC score	0.009481 (rank : 93)	θ value	8.99809 (rank : 99)
Query Neighborhood Hits	104	Target Neighborhood Hits	591	Shared Neighborhood Hits	14
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

GLI1_HUMAN
NC score	0.009089 (rank : 94)	θ value	0.00869519 (rank : 17)
Query Neighborhood Hits	104	Target Neighborhood Hits	828	Shared Neighborhood Hits	3
SwissProt Accessions	P08151, Q8TDN9	Gene names	GLI1, GLI
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI1 (Glioma-associated oncogene) (Oncogene GLI).

CASP_MOUSE
NC score	0.008861 (rank : 95)	θ value	6.88961 (rank : 82)
Query Neighborhood Hits	104	Target Neighborhood Hits	1152	Shared Neighborhood Hits	19
SwissProt Accessions	P70403, Q7TQJ4, Q91WN6	Gene names	Cutl1
Domain Architecture	No domain graphic available
Description	Protein CASP.

K2C8_MOUSE
NC score	0.008726 (rank : 96)	θ value	6.88961 (rank : 85)
Query Neighborhood Hits	104	Target Neighborhood Hits	576	Shared Neighborhood Hits	11
SwissProt Accessions	P11679, Q3KQK5, Q3TGI1, Q3TJE1, Q3TKY7, Q61463, Q61518, Q61519	Gene names	Krt8, Krt2-8
Domain Architecture
Description	Keratin, type II cytoskeletal 8 (Cytokeratin-8) (CK-8) (Keratin-8) (K8) (Cytokeratin endo A).

SCN4A_HUMAN
NC score	0.008658 (rank : 97)	θ value	1.38821 (rank : 44)
Query Neighborhood Hits	104	Target Neighborhood Hits	133	Shared Neighborhood Hits	3
SwissProt Accessions	P35499, Q15478, Q16447, Q7Z6B1	Gene names	SCN4A
Domain Architecture
Description	Sodium channel protein type 4 subunit alpha (Sodium channel protein type IV subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.4) (Sodium channel protein, skeletal muscle subunit alpha) (SkM1).

UBP31_HUMAN
NC score	0.007881 (rank : 98)	θ value	8.99809 (rank : 103)
Query Neighborhood Hits	104	Target Neighborhood Hits	293	Shared Neighborhood Hits	10
SwissProt Accessions	Q70CQ4, Q6AW97, Q6ZTC0, Q6ZTN2, Q9ULL7	Gene names	USP31, KIAA1203
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 31 (EC 3.1.2.15) (Ubiquitin thioesterase 31) (Ubiquitin-specific-processing protease 31) (Deubiquitinating enzyme 31).

CABP4_MOUSE
NC score	0.007827 (rank : 99)	θ value	6.88961 (rank : 81)
Query Neighborhood Hits	104	Target Neighborhood Hits	212	Shared Neighborhood Hits	6
SwissProt Accessions	Q8VHC5	Gene names	Cabp4
Domain Architecture	No domain graphic available
Description	Calcium-binding protein 4 (CaBP4).

XYLT2_MOUSE
NC score	0.007779 (rank : 100)	θ value	8.99809 (rank : 104)
Query Neighborhood Hits	104	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	Q9EPL0, Q5SUY1, Q8K060	Gene names	Xylt2
Domain Architecture	No domain graphic available
Description	Xylosyltransferase 2 (EC 2.4.2.26) (Xylosyltransferase II) (Peptide O- xylosyltransferase 2).

OBSL1_HUMAN
NC score	0.007403 (rank : 101)	θ value	6.88961 (rank : 86)
Query Neighborhood Hits	104	Target Neighborhood Hits	354	Shared Neighborhood Hits	3
SwissProt Accessions	O75147, Q96IW3	Gene names	OBSL1, KIAA0657
Domain Architecture	No domain graphic available
Description	Obscurin-like protein 1 precursor.

CABP4_HUMAN
NC score	0.007132 (rank : 102)	θ value	6.88961 (rank : 80)
Query Neighborhood Hits	104	Target Neighborhood Hits	250	Shared Neighborhood Hits	3
SwissProt Accessions	P57796, Q8N4Z2, Q8WWY5	Gene names	CABP4
Domain Architecture
Description	Calcium-binding protein 4 (CaBP4).

PRP4B_MOUSE
NC score	0.006880 (rank : 103)	θ value	4.03905 (rank : 67)
Query Neighborhood Hits	104	Target Neighborhood Hits	1040	Shared Neighborhood Hits	21
SwissProt Accessions	Q61136, O88378, Q8BND8, Q8R4Y5, Q9CTL9, Q9CTT0	Gene names	Prpf4b, Cbp143, Prp4h, Prp4k, Prp4m, Prpk
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (Pre-mRNA protein kinase).

TEKT1_HUMAN
NC score	0.005682 (rank : 104)	θ value	8.99809 (rank : 101)
Query Neighborhood Hits	104	Target Neighborhood Hits	289	Shared Neighborhood Hits	5
SwissProt Accessions	Q969V4	Gene names	TEKT1
Domain Architecture
Description	Tektin-1.

GPR98_HUMAN
NC score	0.005390 (rank : 105)	θ value	8.99809 (rank : 95)
Query Neighborhood Hits	104	Target Neighborhood Hits	202	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WXG9, O75171, Q9H0X5, Q9UL61	Gene names	GPR98, KIAA0686, MASS1, VLGR1
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 98 precursor (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Very large G-protein coupled receptor 1) (Usher syndrome type-2C protein).

OBSCN_HUMAN
NC score	0.004024 (rank : 106)	θ value	1.38821 (rank : 43)
Query Neighborhood Hits	104	Target Neighborhood Hits	1931	Shared Neighborhood Hits	18
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

MAST1_MOUSE
NC score	0.003841 (rank : 107)	θ value	4.03905 (rank : 66)
Query Neighborhood Hits	104	Target Neighborhood Hits	1123	Shared Neighborhood Hits	9
SwissProt Accessions	Q9R1L5, Q7TQG9, Q80TN0	Gene names	Mast1, Kiaa0973, Sast
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

FOXGA_HUMAN
NC score	0.003483 (rank : 108)	θ value	6.88961 (rank : 84)
Query Neighborhood Hits	104	Target Neighborhood Hits	132	Shared Neighborhood Hits	3
SwissProt Accessions	P55316	Gene names	FOXG1A, FKHL2
Domain Architecture
Description	Forkhead box protein G1A (Forkhead-related protein FKHL2) (Transcription factor BF-2) (Brain factor 2) (BF2) (HFK2).

PEG3_MOUSE
NC score	0.003010 (rank : 109)	θ value	1.06291 (rank : 39)
Query Neighborhood Hits	104	Target Neighborhood Hits	1101	Shared Neighborhood Hits	13
SwissProt Accessions	Q3URU2, O54978, Q3TQ69, Q5EBP7, Q61138, Q6GQS0, Q80U47, Q8R5N0, Q9QX53	Gene names	Peg3, Kiaa0287, Pw1
Domain Architecture	No domain graphic available
Description	Paternally expressed gene 3 protein (ASF-1).

CSMD2_HUMAN
NC score	0.002457 (rank : 110)	θ value	8.99809 (rank : 93)
Query Neighborhood Hits	104	Target Neighborhood Hits	188	Shared Neighborhood Hits	2
SwissProt Accessions	Q7Z408, Q5VT59, Q8N963, Q96Q03, Q9H4V7, Q9H4V8, Q9H4V9, Q9H4W0, Q9H4W1, Q9H4W2, Q9H4W3, Q9H4W4, Q9HCY5, Q9HCY6, Q9HCY7	Gene names	CSMD2, KIAA1884
Domain Architecture
Description	CUB and sushi domain-containing protein 2 (CUB and sushi multiple domains protein 2).

RAI14_MOUSE
NC score	0.001906 (rank : 111)	θ value	5.27518 (rank : 74)
Query Neighborhood Hits	104	Target Neighborhood Hits	1505	Shared Neighborhood Hits	24
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

DCAK3_MOUSE
NC score	0.000150 (rank : 112)	θ value	8.99809 (rank : 94)
Query Neighborhood Hits	104	Target Neighborhood Hits	922	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BWQ5, Q1A748	Gene names	Dcamkl3
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase DCAMKL3 (EC 2.7.11.1) (Doublecortin- like and CAM kinase-like 3) (CLICK-I and II-related) (CLr).