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Network neighborhood for query Sequence : PR285_HUMAN

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PR285_HUMAN
SwissProt Accessions	Q9BYK8, Q3C2G2, Q4VXQ1, Q8TEF3, Q96ND3, Q9C094	Gene names	PRIC285, KIAA1769
Domain Architecture
Description	Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein (EC 3.6.1.-) (ATP-dependent helicase PRIC285) (PPAR-alpha- interacting complex protein 285) (PPAR-gamma DBD-interacting protein 1) (PDIP1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PR285_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	63	Target Neighborhood Hits	63	Shared Neighborhood Hits	63
SwissProt Accessions	Q9BYK8, Q3C2G2, Q4VXQ1, Q8TEF3, Q96ND3, Q9C094	Gene names	PRIC285, KIAA1769
Domain Architecture
Description	Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein (EC 3.6.1.-) (ATP-dependent helicase PRIC285) (PPAR-alpha- interacting complex protein 285) (PPAR-gamma DBD-interacting protein 1) (PDIP1).

HELZ_HUMAN
θ value	2.20485e-131 (rank : 2)	NC score	0.851997 (rank : 2)
Query Neighborhood Hits	63	Target Neighborhood Hits	198	Shared Neighborhood Hits	22
SwissProt Accessions	P42694	Gene names	HELZ, KIAA0054
Domain Architecture	No domain graphic available
Description	Probable helicase with zinc-finger domain (EC 3.6.1.-).

RENT1_HUMAN
θ value	2.18568e-46 (rank : 3)	NC score	0.783493 (rank : 3)
Query Neighborhood Hits	63	Target Neighborhood Hits	51	Shared Neighborhood Hits	18
SwissProt Accessions	Q92900, O00239, O43343, Q86Z25, Q92842	Gene names	UPF1, KIAA0221, RENT1
Domain Architecture
Description	Regulator of nonsense transcripts 1 (EC 3.6.1.-) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up- frameshift suppressor 1 homolog) (hUpf1).

RENT1_MOUSE
θ value	2.85459e-46 (rank : 4)	NC score	0.783328 (rank : 4)
Query Neighborhood Hits	63	Target Neighborhood Hits	54	Shared Neighborhood Hits	17
SwissProt Accessions	Q9EPU0, Q99PR4	Gene names	Upf1, Rent1
Domain Architecture
Description	Regulator of nonsense transcripts 1 (EC 3.6.1.-) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up- frameshift suppressor 1 homolog) (mUpf1).

M10L1_HUMAN
θ value	1.37539e-32 (rank : 5)	NC score	0.729842 (rank : 5)
Query Neighborhood Hits	63	Target Neighborhood Hits	36	Shared Neighborhood Hits	20
SwissProt Accessions	Q9BXT6, Q5TGD5, Q8NBD4, Q9NXW3, Q9UFB3, Q9UGX9	Gene names	MOV10L1
Domain Architecture
Description	Putative helicase Mov10l1 (EC 3.6.1.-) (Moloney leukemia virus 10-like protein 1) (MOV10-like 1).

M10L1_MOUSE
θ value	9.8567e-31 (rank : 6)	NC score	0.724986 (rank : 8)
Query Neighborhood Hits	63	Target Neighborhood Hits	59	Shared Neighborhood Hits	19
SwissProt Accessions	Q99MV5, Q7TPA9, Q8C3W0, Q924C2	Gene names	Mov10l1, Champ
Domain Architecture
Description	Putative helicase Mov10l1 (EC 3.6.1.-) (Moloney leukemia virus 10-like protein 1) (MOV10-like 1) (Cardiac helicase activated by MEF2 protein) (Cardiac-specific RNA helicase).

SMBP2_MOUSE
θ value	8.3442e-30 (rank : 7)	NC score	0.714336 (rank : 9)
Query Neighborhood Hits	63	Target Neighborhood Hits	104	Shared Neighborhood Hits	18
SwissProt Accessions	P40694	Gene names	Ighmbp2, Smbp-2, Smbp2
Domain Architecture
Description	DNA-binding protein SMUBP-2 (EC 3.6.1.-) (ATP-dependent helicase IGHMBP2) (Immunoglobulin mu-binding protein 2) (SMUBP-2) (Cardiac transcription factor 1) (CATF1).

MOV10_MOUSE
θ value	1.12775e-26 (rank : 8)	NC score	0.726550 (rank : 6)
Query Neighborhood Hits	63	Target Neighborhood Hits	39	Shared Neighborhood Hits	19
SwissProt Accessions	P23249, Q9DC64	Gene names	Mov10, Gb110
Domain Architecture
Description	Putative helicase MOV-10 (EC 3.6.1.-) (Moloney leukemia virus 10 protein).

MOV10_HUMAN
θ value	2.51237e-26 (rank : 9)	NC score	0.725220 (rank : 7)
Query Neighborhood Hits	63	Target Neighborhood Hits	46	Shared Neighborhood Hits	19
SwissProt Accessions	Q9HCE1, Q8TEF0, Q9BSY3, Q9BUJ9	Gene names	MOV10, KIAA1631
Domain Architecture
Description	Putative helicase MOV-10 (EC 3.6.1.-) (Moloney leukemia virus 10 protein).

SMBP2_HUMAN
θ value	3.62785e-25 (rank : 10)	NC score	0.708850 (rank : 10)
Query Neighborhood Hits	63	Target Neighborhood Hits	107	Shared Neighborhood Hits	20
SwissProt Accessions	P38935, Q00443, Q14177	Gene names	IGHMBP2, SMBP2, SMUBP2
Domain Architecture
Description	DNA-binding protein SMUBP-2 (EC 3.6.1.-) (ATP-dependent helicase IGHMBP2) (Immunoglobulin mu-binding protein 2) (SMUBP-2) (Glial factor 1) (GF-1).

RRP44_HUMAN
θ value	3.07116e-24 (rank : 11)	NC score	0.362803 (rank : 16)
Query Neighborhood Hits	63	Target Neighborhood Hits	35	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y2L1, Q5W0P7, Q5W0P8, Q658Z7, Q7Z481, Q8WWI2, Q9UG36	Gene names	DIS3, KIAA1008, RRP44
Domain Architecture
Description	Exosome complex exonuclease RRP44 (EC 3.1.13.-) (Ribosomal RNA- processing protein 44) (DIS3 protein homolog).

SETX_HUMAN
θ value	6.84181e-24 (rank : 12)	NC score	0.636749 (rank : 11)
Query Neighborhood Hits	63	Target Neighborhood Hits	368	Shared Neighborhood Hits	18
SwissProt Accessions	Q7Z333, O75120, Q3KQX4, Q68DW5, Q6AZD7, Q7Z3J6, Q8WX33, Q9H9D1, Q9NVP9	Gene names	SETX, ALS4, KIAA0625, SCAR1
Domain Architecture
Description	Probable helicase senataxin (EC 3.6.1.-) (SEN1 homolog).

ZNFX1_MOUSE
θ value	3.07829e-16 (rank : 13)	NC score	0.463239 (rank : 12)
Query Neighborhood Hits	63	Target Neighborhood Hits	407	Shared Neighborhood Hits	15
SwissProt Accessions	Q8R151, Q3U016, Q3UD71, Q3UEZ0	Gene names	ZNFX1
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

ZNFX1_HUMAN
θ value	1.29331e-14 (rank : 14)	NC score	0.460263 (rank : 13)
Query Neighborhood Hits	63	Target Neighborhood Hits	308	Shared Neighborhood Hits	15
SwissProt Accessions	Q9P2E3, Q9BQM7, Q9BQM8, Q9H8C1, Q9H9S2, Q9NUM1, Q9NWW1	Gene names	ZNFX1, KIAA1404
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

AQR_HUMAN
θ value	1.06045e-08 (rank : 15)	NC score	0.441107 (rank : 15)
Query Neighborhood Hits	63	Target Neighborhood Hits	88	Shared Neighborhood Hits	15
SwissProt Accessions	O60306, Q2YDX9, Q6IRU8, Q6PIC8	Gene names	AQR, KIAA0560
Domain Architecture	No domain graphic available
Description	Intron-binding protein aquarius (Intron-binding protein of 160 kDa) (IBP160).

AQR_MOUSE
θ value	1.06045e-08 (rank : 16)	NC score	0.443960 (rank : 14)
Query Neighborhood Hits	63	Target Neighborhood Hits	62	Shared Neighborhood Hits	15
SwissProt Accessions	Q8CFQ3, P97871, Q3U9N1, Q3ULE8, Q80TX8	Gene names	Aqr, Kiaa0560
Domain Architecture	No domain graphic available
Description	Intron-binding protein aquarius.

Z3H7A_HUMAN
θ value	5.81887e-07 (rank : 17)	NC score	0.170864 (rank : 18)
Query Neighborhood Hits	63	Target Neighborhood Hits	105	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IWR0, Q9NPE9	Gene names	ZC3H7A, ZC3H7, ZC3HDC7
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH-type domain-containing protein 7A.

Z3H7B_HUMAN
θ value	9.29e-05 (rank : 18)	NC score	0.147465 (rank : 19)
Query Neighborhood Hits	63	Target Neighborhood Hits	109	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UGR2, Q5TFX9, Q8TBT9, Q9H8B6, Q9UGQ9, Q9UGR0, Q9UGR1, Q9UK03, Q9UPW9	Gene names	ZC3H7B, KIAA1031
Domain Architecture
Description	Zinc finger CCCH-type domain-containing protein 7B (Rotavirus 'X'- associated non-structural protein) (RoXaN).

CLIC6_HUMAN
θ value	0.125558 (rank : 19)	NC score	0.028652 (rank : 35)
Query Neighborhood Hits	63	Target Neighborhood Hits	289	Shared Neighborhood Hits	6
SwissProt Accessions	Q96NY7, Q8IX31	Gene names	CLIC6, CLIC1L
Domain Architecture	No domain graphic available
Description	Chloride intracellular channel 6.

NEBU_HUMAN
θ value	0.365318 (rank : 20)	NC score	0.025551 (rank : 37)
Query Neighborhood Hits	63	Target Neighborhood Hits	420	Shared Neighborhood Hits	3
SwissProt Accessions	P20929, Q15346	Gene names	NEB
Domain Architecture
Description	Nebulin.

STRC_HUMAN
θ value	0.47712 (rank : 21)	NC score	0.040794 (rank : 30)
Query Neighborhood Hits	63	Target Neighborhood Hits	32	Shared Neighborhood Hits	4
SwissProt Accessions	Q7RTU9	Gene names	STRC
Domain Architecture	No domain graphic available
Description	Stereocilin precursor.

NAGAB_MOUSE
θ value	0.813845 (rank : 22)	NC score	0.034472 (rank : 33)
Query Neighborhood Hits	63	Target Neighborhood Hits	6	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QWR8, O88620, Q8R437, Q8VDK2	Gene names	Naga
Domain Architecture	No domain graphic available
Description	Alpha-N-acetylgalactosaminidase precursor (EC 3.2.1.49) (Alpha- galactosidase B).

RFC4_HUMAN
θ value	0.813845 (rank : 23)	NC score	0.073827 (rank : 21)
Query Neighborhood Hits	63	Target Neighborhood Hits	64	Shared Neighborhood Hits	12
SwissProt Accessions	P35249, Q6FHX7	Gene names	RFC4
Domain Architecture
Description	Replication factor C subunit 4 (Replication factor C 37 kDa subunit) (RF-C 37 kDa subunit) (RFC37) (Activator 1 37 kDa subunit) (A1 37 kDa subunit).

RFC4_MOUSE
θ value	0.813845 (rank : 24)	NC score	0.075108 (rank : 20)
Query Neighborhood Hits	63	Target Neighborhood Hits	65	Shared Neighborhood Hits	12
SwissProt Accessions	Q99J62	Gene names	Rfc4
Domain Architecture	No domain graphic available
Description	Replication factor C subunit 4.

ZN473_MOUSE
θ value	1.06291 (rank : 25)	NC score	0.000746 (rank : 69)
Query Neighborhood Hits	63	Target Neighborhood Hits	824	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BI67, Q8BI98, Q8BIB7	Gene names	Znf473, Zfp100, Zfp473
Domain Architecture	No domain graphic available
Description	Zinc finger protein 473 homolog (Zinc finger protein 100) (Zfp-100).

ZN638_HUMAN
θ value	1.06291 (rank : 26)	NC score	0.040046 (rank : 31)
Query Neighborhood Hits	63	Target Neighborhood Hits	343	Shared Neighborhood Hits	8
SwissProt Accessions	Q14966, Q53R34, Q5XJ05, Q68DP3, Q6P2H2, Q7Z3T7, Q8NF92, Q8TCA1, Q9H2G1, Q9NP37	Gene names	ZNF638, NP220, ZFML
Domain Architecture	No domain graphic available
Description	Zinc finger protein 638 (Nuclear protein 220) (Zinc-finger matrin-like protein) (Cutaneous T-cell lymphoma-associated antigen se33-1) (CTCL tumor antigen se33-1).

ZN638_MOUSE
θ value	1.06291 (rank : 27)	NC score	0.038436 (rank : 32)
Query Neighborhood Hits	63	Target Neighborhood Hits	318	Shared Neighborhood Hits	5
SwissProt Accessions	Q61464, Q6DFV9, Q8C941	Gene names	Znf638, Np220, Zfml
Domain Architecture	No domain graphic available
Description	Zinc finger protein 638 (Nuclear protein 220) (Zinc-finger matrin-like protein).

ITA2_MOUSE
θ value	1.38821 (rank : 28)	NC score	0.010912 (rank : 57)
Query Neighborhood Hits	63	Target Neighborhood Hits	70	Shared Neighborhood Hits	3
SwissProt Accessions	Q62469, Q62163	Gene names	Itga2
Domain Architecture
Description	Integrin alpha-2 precursor (Platelet membrane glycoprotein Ia) (GPIa) (Collagen receptor) (VLA-2 alpha chain) (CD49b antigen).

RFC5_HUMAN
θ value	1.38821 (rank : 29)	NC score	0.069707 (rank : 23)
Query Neighborhood Hits	63	Target Neighborhood Hits	60	Shared Neighborhood Hits	12
SwissProt Accessions	P40937	Gene names	RFC5
Domain Architecture
Description	Replication factor C subunit 5 (Replication factor C 36 kDa subunit) (RF-C 36 kDa subunit) (RFC36) (Activator 1 36 kDa subunit) (A1 36 kDa subunit).

RFC5_MOUSE
θ value	1.38821 (rank : 30)	NC score	0.072529 (rank : 22)
Query Neighborhood Hits	63	Target Neighborhood Hits	58	Shared Neighborhood Hits	12
SwissProt Accessions	Q9D0F6	Gene names	Rfc5
Domain Architecture
Description	Replication factor C subunit 5 (Replication factor C 36 kDa subunit) (RF-C 36 kDa subunit) (RFC36) (Activator 1 36 kDa subunit) (A1 36 kDa subunit).

ZN142_HUMAN
θ value	1.38821 (rank : 31)	NC score	0.002522 (rank : 64)
Query Neighborhood Hits	63	Target Neighborhood Hits	1007	Shared Neighborhood Hits	13
SwissProt Accessions	P52746, Q92510	Gene names	ZNF142, KIAA0236
Domain Architecture	No domain graphic available
Description	Zinc finger protein 142 (HA4654).

AKAP2_MOUSE
θ value	2.36792 (rank : 32)	NC score	0.025505 (rank : 38)
Query Neighborhood Hits	63	Target Neighborhood Hits	385	Shared Neighborhood Hits	6
SwissProt Accessions	O54931, O54932, O54933	Gene names	Akap2
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2) (AKAP expressed in kidney and lung) (AKAP-KL).

BRPF3_HUMAN
θ value	2.36792 (rank : 33)	NC score	0.013120 (rank : 52)
Query Neighborhood Hits	63	Target Neighborhood Hits	217	Shared Neighborhood Hits	5
SwissProt Accessions	Q9ULD4, Q5R3K8	Gene names	BRPF3, KIAA1286
Domain Architecture	No domain graphic available
Description	Bromodomain and PHD finger-containing protein 3.

CIZ1_HUMAN
θ value	2.36792 (rank : 34)	NC score	0.031403 (rank : 34)
Query Neighborhood Hits	63	Target Neighborhood Hits	359	Shared Neighborhood Hits	7
SwissProt Accessions	Q9ULV3, Q9NYM8, Q9UHK4, Q9Y3F9, Q9Y3G0	Gene names	CIZ1, LSFR1, NP94
Domain Architecture	No domain graphic available
Description	Cip1-interacting zinc finger protein (Nuclear protein NP94).

TIF1B_MOUSE
θ value	2.36792 (rank : 35)	NC score	0.016697 (rank : 44)
Query Neighborhood Hits	63	Target Neighborhood Hits	276	Shared Neighborhood Hits	6
SwissProt Accessions	Q62318, P70391, Q8C283, Q99PN4	Gene names	Trim28, Krip1, Tif1b
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (KRAB-A-interacting protein) (KRIP-1).

ARMX5_MOUSE
θ value	3.0926 (rank : 36)	NC score	0.016307 (rank : 46)
Query Neighborhood Hits	63	Target Neighborhood Hits	46	Shared Neighborhood Hits	2
SwissProt Accessions	Q3UZB0	Gene names	Armcx5
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 5.

EPIPL_MOUSE
θ value	3.0926 (rank : 37)	NC score	0.014312 (rank : 48)
Query Neighborhood Hits	63	Target Neighborhood Hits	118	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R0W0	Gene names	Eppk1
Domain Architecture
Description	Epiplakin.

MLL3_HUMAN
θ value	3.0926 (rank : 38)	NC score	0.019805 (rank : 40)
Query Neighborhood Hits	63	Target Neighborhood Hits	1644	Shared Neighborhood Hits	19
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MAST4_HUMAN
θ value	4.03905 (rank : 39)	NC score	0.002017 (rank : 66)
Query Neighborhood Hits	63	Target Neighborhood Hits	1804	Shared Neighborhood Hits	9
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

OGFR_HUMAN
θ value	4.03905 (rank : 40)	NC score	0.007277 (rank : 60)
Query Neighborhood Hits	63	Target Neighborhood Hits	1582	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

TIF1A_MOUSE
θ value	4.03905 (rank : 41)	NC score	0.012636 (rank : 53)
Query Neighborhood Hits	63	Target Neighborhood Hits	307	Shared Neighborhood Hits	8
SwissProt Accessions	Q64127, Q64126	Gene names	Trim24, Tif1, Tif1a
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24).

TNF10_MOUSE
θ value	4.03905 (rank : 42)	NC score	0.019494 (rank : 41)
Query Neighborhood Hits	63	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	P50592	Gene names	Tnfsf10, Trail
Domain Architecture
Description	Tumor necrosis factor ligand superfamily member 10 (TNF-related apoptosis-inducing ligand) (Protein TRAIL) (CD253 antigen).

ASAHL_HUMAN
θ value	5.27518 (rank : 43)	NC score	0.016374 (rank : 45)
Query Neighborhood Hits	63	Target Neighborhood Hits	6	Shared Neighborhood Hits	2
SwissProt Accessions	Q02083, Q5KTF2, Q96EY2, Q9BRA8	Gene names	ASAHL, NAAA, PLT
Domain Architecture
Description	N-acylethanolamine-hydrolyzing acid amidase precursor (EC 3.5.1.-) (N- acylsphingosine amidohydrolase-like) (ASAH-like protein) (Acid ceramidase-like protein).

EDD1_MOUSE
θ value	5.27518 (rank : 44)	NC score	0.014261 (rank : 49)
Query Neighborhood Hits	63	Target Neighborhood Hits	167	Shared Neighborhood Hits	4
SwissProt Accessions	Q80TP3, Q698K9, Q6PEQ8, Q6PFQ9, Q80VL4, Q810V6, Q9CXE9	Gene names	Edd1, Edd, Kiaa0896
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog).

FBN1_HUMAN
θ value	5.27518 (rank : 45)	NC score	0.001926 (rank : 67)
Query Neighborhood Hits	63	Target Neighborhood Hits	557	Shared Neighborhood Hits	2
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

FUT4_HUMAN
θ value	5.27518 (rank : 46)	NC score	0.011280 (rank : 56)
Query Neighborhood Hits	63	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	P22083	Gene names	FUT4, ELFT
Domain Architecture
Description	Alpha-(1,3)-fucosyltransferase (EC 2.4.1.-) (Galactoside 3-L- fucosyltransferase) (Fucosyltransferase 4) (FUCT-IV) (Fuc-TIV) (ELAM-1 ligand fucosyltransferase).

YETS2_HUMAN
θ value	5.27518 (rank : 47)	NC score	0.013623 (rank : 50)
Query Neighborhood Hits	63	Target Neighborhood Hits	212	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ULM3, Q641P6, Q9NW96	Gene names	YEATS2, KIAA1197
Domain Architecture	No domain graphic available
Description	YEATS domain-containing protein 2.

ZN622_MOUSE
θ value	5.27518 (rank : 48)	NC score	0.018234 (rank : 43)
Query Neighborhood Hits	63	Target Neighborhood Hits	28	Shared Neighborhood Hits	3
SwissProt Accessions	Q91VY9	Gene names	Znf622, D15Ertd806e, Zfp622
Domain Architecture	No domain graphic available
Description	Zinc finger protein 622.

AKAP2_HUMAN
θ value	6.88961 (rank : 49)	NC score	0.019095 (rank : 42)
Query Neighborhood Hits	63	Target Neighborhood Hits	507	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y2D5, Q9UG26	Gene names	AKAP2, KIAA0920
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2).

DDX51_HUMAN
θ value	6.88961 (rank : 50)	NC score	0.005515 (rank : 61)
Query Neighborhood Hits	63	Target Neighborhood Hits	332	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N8A6, Q5CZ71, Q8IXK5, Q96ED1	Gene names	DDX51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

EDD1_HUMAN
θ value	6.88961 (rank : 51)	NC score	0.013431 (rank : 51)
Query Neighborhood Hits	63	Target Neighborhood Hits	170	Shared Neighborhood Hits	4
SwissProt Accessions	O95071, O94970, Q9NPL3	Gene names	EDD1, EDD, HYD, KIAA0896
Domain Architecture
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog) (hHYD) (Progestin-induced protein).

FBX32_HUMAN
θ value	6.88961 (rank : 52)	NC score	0.011781 (rank : 55)
Query Neighborhood Hits	63	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	Q969P5	Gene names	FBXO32
Domain Architecture	No domain graphic available
Description	F-box only protein 32 (Muscle atrophy F-box protein) (MAFbx) (Atrogin- 1).

GCP5_HUMAN
θ value	6.88961 (rank : 53)	NC score	0.016280 (rank : 47)
Query Neighborhood Hits	63	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	Q96RT8, Q96PY8	Gene names	TUBGCP5, GCP5, KIAA1899
Domain Architecture
Description	Gamma-tubulin complex component 5 (GCP-5).

NAGAB_HUMAN
θ value	6.88961 (rank : 54)	NC score	0.023577 (rank : 39)
Query Neighborhood Hits	63	Target Neighborhood Hits	5	Shared Neighborhood Hits	3
SwissProt Accessions	P17050	Gene names	NAGA
Domain Architecture
Description	Alpha-N-acetylgalactosaminidase precursor (EC 3.2.1.49) (Alpha- galactosidase B).

SPTN2_HUMAN
θ value	6.88961 (rank : 55)	NC score	0.003795 (rank : 62)
Query Neighborhood Hits	63	Target Neighborhood Hits	535	Shared Neighborhood Hits	4
SwissProt Accessions	O15020, O14872, O14873	Gene names	SPTBN2, KIAA0302
Domain Architecture
Description	Spectrin beta chain, brain 2 (Spectrin, non-erythroid beta chain 2) (Beta-III spectrin).

STRC_MOUSE
θ value	6.88961 (rank : 56)	NC score	0.028143 (rank : 36)
Query Neighborhood Hits	63	Target Neighborhood Hits	89	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VIM6	Gene names	Strc
Domain Architecture	No domain graphic available
Description	Stereocilin precursor.

AAKG3_MOUSE
θ value	8.99809 (rank : 57)	NC score	0.008106 (rank : 59)
Query Neighborhood Hits	63	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BGM7, Q80WK8, Q8CJ41	Gene names	Prkag3
Domain Architecture	No domain graphic available
Description	5'-AMP-activated protein kinase subunit gamma-3 (AMPK gamma-3 chain) (AMPK gamma3).

ATX2L_MOUSE
θ value	8.99809 (rank : 58)	NC score	0.010493 (rank : 58)
Query Neighborhood Hits	63	Target Neighborhood Hits	401	Shared Neighborhood Hits	6
SwissProt Accessions	Q7TQH0, Q80XN9, Q8K059	Gene names	Atxn2l, A2lp
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein.

GSHB_HUMAN
θ value	8.99809 (rank : 59)	NC score	0.012414 (rank : 54)
Query Neighborhood Hits	63	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	P48637, Q4TTD9	Gene names	GSS
Domain Architecture
Description	Glutathione synthetase (EC 6.3.2.3) (Glutathione synthase) (GSH synthetase) (GSH-S).

SHAN1_HUMAN
θ value	8.99809 (rank : 60)	NC score	0.002282 (rank : 65)
Query Neighborhood Hits	63	Target Neighborhood Hits	1041	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

WD51A_MOUSE
θ value	8.99809 (rank : 61)	NC score	0.000945 (rank : 68)
Query Neighborhood Hits	63	Target Neighborhood Hits	342	Shared Neighborhood Hits	2
SwissProt Accessions	Q8JZX3, Q9CY09	Gene names	Wdr51a
Domain Architecture	No domain graphic available
Description	WD repeat protein 51A.

ZN174_HUMAN
θ value	8.99809 (rank : 62)	NC score	-0.000752 (rank : 70)
Query Neighborhood Hits	63	Target Neighborhood Hits	744	Shared Neighborhood Hits	5
SwissProt Accessions	Q15697, Q9BQ34	Gene names	ZNF174, ZSCAN8
Domain Architecture
Description	Zinc finger protein 174 (AW-1) (Zinc finger and SCAN domain-containing protein 8).

ZN451_MOUSE
θ value	8.99809 (rank : 63)	NC score	0.003312 (rank : 63)
Query Neighborhood Hits	63	Target Neighborhood Hits	643	Shared Neighborhood Hits	5
SwissProt Accessions	Q8C0P7	Gene names	Znf451, Zfp451
Domain Architecture	No domain graphic available
Description	Zinc finger protein 451.

CX048_HUMAN
θ value	θ > 10 (rank : 64)	NC score	0.197890 (rank : 17)
Query Neighborhood Hits	63	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WUE5, Q9NWY8	Gene names	CXorf48
Domain Architecture	No domain graphic available
Description	Protein CXorf48 (Tumor antigen BJ-HCC-20).

SPR2B_MOUSE
θ value	θ > 10 (rank : 65)	NC score	0.060461 (rank : 26)
Query Neighborhood Hits	63	Target Neighborhood Hits	51	Shared Neighborhood Hits	2
SwissProt Accessions	O70554, Q7TSB2	Gene names	Sprr2b
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2B.

SPR2D_MOUSE
θ value	θ > 10 (rank : 66)	NC score	0.061973 (rank : 24)
Query Neighborhood Hits	63	Target Neighborhood Hits	61	Shared Neighborhood Hits	2
SwissProt Accessions	O70555	Gene names	Sprr2d
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2D.

SPR2E_HUMAN
θ value	θ > 10 (rank : 67)	NC score	0.056560 (rank : 28)
Query Neighborhood Hits	63	Target Neighborhood Hits	32	Shared Neighborhood Hits	2
SwissProt Accessions	P22531, Q96RM2	Gene names	SPRR2E
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2E (SPR-2E) (Small proline-rich protein II) (SPR-II).

SPR2F_HUMAN
θ value	θ > 10 (rank : 68)	NC score	0.060637 (rank : 25)
Query Neighborhood Hits	63	Target Neighborhood Hits	33	Shared Neighborhood Hits	2
SwissProt Accessions	Q96RM1	Gene names	SPRR2F
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2F (SPR-2F).

SPR2G_MOUSE
θ value	θ > 10 (rank : 69)	NC score	0.060150 (rank : 27)
Query Neighborhood Hits	63	Target Neighborhood Hits	53	Shared Neighborhood Hits	2
SwissProt Accessions	O70558	Gene names	Sprr2g
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2G.

SPR2H_MOUSE
θ value	θ > 10 (rank : 70)	NC score	0.053769 (rank : 29)
Query Neighborhood Hits	63	Target Neighborhood Hits	82	Shared Neighborhood Hits	3
SwissProt Accessions	O70559	Gene names	Sprr2h
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2H.

Hits sorted by NC score

PR285_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	63	Target Neighborhood Hits	63	Shared Neighborhood Hits	63
SwissProt Accessions	Q9BYK8, Q3C2G2, Q4VXQ1, Q8TEF3, Q96ND3, Q9C094	Gene names	PRIC285, KIAA1769
Domain Architecture
Description	Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein (EC 3.6.1.-) (ATP-dependent helicase PRIC285) (PPAR-alpha- interacting complex protein 285) (PPAR-gamma DBD-interacting protein 1) (PDIP1).

HELZ_HUMAN
NC score	0.851997 (rank : 2)	θ value	2.20485e-131 (rank : 2)
Query Neighborhood Hits	63	Target Neighborhood Hits	198	Shared Neighborhood Hits	22
SwissProt Accessions	P42694	Gene names	HELZ, KIAA0054
Domain Architecture	No domain graphic available
Description	Probable helicase with zinc-finger domain (EC 3.6.1.-).

RENT1_HUMAN
NC score	0.783493 (rank : 3)	θ value	2.18568e-46 (rank : 3)
Query Neighborhood Hits	63	Target Neighborhood Hits	51	Shared Neighborhood Hits	18
SwissProt Accessions	Q92900, O00239, O43343, Q86Z25, Q92842	Gene names	UPF1, KIAA0221, RENT1
Domain Architecture
Description	Regulator of nonsense transcripts 1 (EC 3.6.1.-) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up- frameshift suppressor 1 homolog) (hUpf1).

RENT1_MOUSE
NC score	0.783328 (rank : 4)	θ value	2.85459e-46 (rank : 4)
Query Neighborhood Hits	63	Target Neighborhood Hits	54	Shared Neighborhood Hits	17
SwissProt Accessions	Q9EPU0, Q99PR4	Gene names	Upf1, Rent1
Domain Architecture
Description	Regulator of nonsense transcripts 1 (EC 3.6.1.-) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up- frameshift suppressor 1 homolog) (mUpf1).

M10L1_HUMAN
NC score	0.729842 (rank : 5)	θ value	1.37539e-32 (rank : 5)
Query Neighborhood Hits	63	Target Neighborhood Hits	36	Shared Neighborhood Hits	20
SwissProt Accessions	Q9BXT6, Q5TGD5, Q8NBD4, Q9NXW3, Q9UFB3, Q9UGX9	Gene names	MOV10L1
Domain Architecture
Description	Putative helicase Mov10l1 (EC 3.6.1.-) (Moloney leukemia virus 10-like protein 1) (MOV10-like 1).

MOV10_MOUSE
NC score	0.726550 (rank : 6)	θ value	1.12775e-26 (rank : 8)
Query Neighborhood Hits	63	Target Neighborhood Hits	39	Shared Neighborhood Hits	19
SwissProt Accessions	P23249, Q9DC64	Gene names	Mov10, Gb110
Domain Architecture
Description	Putative helicase MOV-10 (EC 3.6.1.-) (Moloney leukemia virus 10 protein).

MOV10_HUMAN
NC score	0.725220 (rank : 7)	θ value	2.51237e-26 (rank : 9)
Query Neighborhood Hits	63	Target Neighborhood Hits	46	Shared Neighborhood Hits	19
SwissProt Accessions	Q9HCE1, Q8TEF0, Q9BSY3, Q9BUJ9	Gene names	MOV10, KIAA1631
Domain Architecture
Description	Putative helicase MOV-10 (EC 3.6.1.-) (Moloney leukemia virus 10 protein).

M10L1_MOUSE
NC score	0.724986 (rank : 8)	θ value	9.8567e-31 (rank : 6)
Query Neighborhood Hits	63	Target Neighborhood Hits	59	Shared Neighborhood Hits	19
SwissProt Accessions	Q99MV5, Q7TPA9, Q8C3W0, Q924C2	Gene names	Mov10l1, Champ
Domain Architecture
Description	Putative helicase Mov10l1 (EC 3.6.1.-) (Moloney leukemia virus 10-like protein 1) (MOV10-like 1) (Cardiac helicase activated by MEF2 protein) (Cardiac-specific RNA helicase).

SMBP2_MOUSE
NC score	0.714336 (rank : 9)	θ value	8.3442e-30 (rank : 7)
Query Neighborhood Hits	63	Target Neighborhood Hits	104	Shared Neighborhood Hits	18
SwissProt Accessions	P40694	Gene names	Ighmbp2, Smbp-2, Smbp2
Domain Architecture
Description	DNA-binding protein SMUBP-2 (EC 3.6.1.-) (ATP-dependent helicase IGHMBP2) (Immunoglobulin mu-binding protein 2) (SMUBP-2) (Cardiac transcription factor 1) (CATF1).

SMBP2_HUMAN
NC score	0.708850 (rank : 10)	θ value	3.62785e-25 (rank : 10)
Query Neighborhood Hits	63	Target Neighborhood Hits	107	Shared Neighborhood Hits	20
SwissProt Accessions	P38935, Q00443, Q14177	Gene names	IGHMBP2, SMBP2, SMUBP2
Domain Architecture
Description	DNA-binding protein SMUBP-2 (EC 3.6.1.-) (ATP-dependent helicase IGHMBP2) (Immunoglobulin mu-binding protein 2) (SMUBP-2) (Glial factor 1) (GF-1).

SETX_HUMAN
NC score	0.636749 (rank : 11)	θ value	6.84181e-24 (rank : 12)
Query Neighborhood Hits	63	Target Neighborhood Hits	368	Shared Neighborhood Hits	18
SwissProt Accessions	Q7Z333, O75120, Q3KQX4, Q68DW5, Q6AZD7, Q7Z3J6, Q8WX33, Q9H9D1, Q9NVP9	Gene names	SETX, ALS4, KIAA0625, SCAR1
Domain Architecture
Description	Probable helicase senataxin (EC 3.6.1.-) (SEN1 homolog).

ZNFX1_MOUSE
NC score	0.463239 (rank : 12)	θ value	3.07829e-16 (rank : 13)
Query Neighborhood Hits	63	Target Neighborhood Hits	407	Shared Neighborhood Hits	15
SwissProt Accessions	Q8R151, Q3U016, Q3UD71, Q3UEZ0	Gene names	ZNFX1
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

ZNFX1_HUMAN
NC score	0.460263 (rank : 13)	θ value	1.29331e-14 (rank : 14)
Query Neighborhood Hits	63	Target Neighborhood Hits	308	Shared Neighborhood Hits	15
SwissProt Accessions	Q9P2E3, Q9BQM7, Q9BQM8, Q9H8C1, Q9H9S2, Q9NUM1, Q9NWW1	Gene names	ZNFX1, KIAA1404
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

AQR_MOUSE
NC score	0.443960 (rank : 14)	θ value	1.06045e-08 (rank : 16)
Query Neighborhood Hits	63	Target Neighborhood Hits	62	Shared Neighborhood Hits	15
SwissProt Accessions	Q8CFQ3, P97871, Q3U9N1, Q3ULE8, Q80TX8	Gene names	Aqr, Kiaa0560
Domain Architecture	No domain graphic available
Description	Intron-binding protein aquarius.

AQR_HUMAN
NC score	0.441107 (rank : 15)	θ value	1.06045e-08 (rank : 15)
Query Neighborhood Hits	63	Target Neighborhood Hits	88	Shared Neighborhood Hits	15
SwissProt Accessions	O60306, Q2YDX9, Q6IRU8, Q6PIC8	Gene names	AQR, KIAA0560
Domain Architecture	No domain graphic available
Description	Intron-binding protein aquarius (Intron-binding protein of 160 kDa) (IBP160).

RRP44_HUMAN
NC score	0.362803 (rank : 16)	θ value	3.07116e-24 (rank : 11)
Query Neighborhood Hits	63	Target Neighborhood Hits	35	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y2L1, Q5W0P7, Q5W0P8, Q658Z7, Q7Z481, Q8WWI2, Q9UG36	Gene names	DIS3, KIAA1008, RRP44
Domain Architecture
Description	Exosome complex exonuclease RRP44 (EC 3.1.13.-) (Ribosomal RNA- processing protein 44) (DIS3 protein homolog).

CX048_HUMAN
NC score	0.197890 (rank : 17)	θ value	θ > 10 (rank : 64)
Query Neighborhood Hits	63	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WUE5, Q9NWY8	Gene names	CXorf48
Domain Architecture	No domain graphic available
Description	Protein CXorf48 (Tumor antigen BJ-HCC-20).

Z3H7A_HUMAN
NC score	0.170864 (rank : 18)	θ value	5.81887e-07 (rank : 17)
Query Neighborhood Hits	63	Target Neighborhood Hits	105	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IWR0, Q9NPE9	Gene names	ZC3H7A, ZC3H7, ZC3HDC7
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH-type domain-containing protein 7A.

Z3H7B_HUMAN
NC score	0.147465 (rank : 19)	θ value	9.29e-05 (rank : 18)
Query Neighborhood Hits	63	Target Neighborhood Hits	109	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UGR2, Q5TFX9, Q8TBT9, Q9H8B6, Q9UGQ9, Q9UGR0, Q9UGR1, Q9UK03, Q9UPW9	Gene names	ZC3H7B, KIAA1031
Domain Architecture
Description	Zinc finger CCCH-type domain-containing protein 7B (Rotavirus 'X'- associated non-structural protein) (RoXaN).

RFC4_MOUSE
NC score	0.075108 (rank : 20)	θ value	0.813845 (rank : 24)
Query Neighborhood Hits	63	Target Neighborhood Hits	65	Shared Neighborhood Hits	12
SwissProt Accessions	Q99J62	Gene names	Rfc4
Domain Architecture	No domain graphic available
Description	Replication factor C subunit 4.

RFC4_HUMAN
NC score	0.073827 (rank : 21)	θ value	0.813845 (rank : 23)
Query Neighborhood Hits	63	Target Neighborhood Hits	64	Shared Neighborhood Hits	12
SwissProt Accessions	P35249, Q6FHX7	Gene names	RFC4
Domain Architecture
Description	Replication factor C subunit 4 (Replication factor C 37 kDa subunit) (RF-C 37 kDa subunit) (RFC37) (Activator 1 37 kDa subunit) (A1 37 kDa subunit).

RFC5_MOUSE
NC score	0.072529 (rank : 22)	θ value	1.38821 (rank : 30)
Query Neighborhood Hits	63	Target Neighborhood Hits	58	Shared Neighborhood Hits	12
SwissProt Accessions	Q9D0F6	Gene names	Rfc5
Domain Architecture
Description	Replication factor C subunit 5 (Replication factor C 36 kDa subunit) (RF-C 36 kDa subunit) (RFC36) (Activator 1 36 kDa subunit) (A1 36 kDa subunit).

RFC5_HUMAN
NC score	0.069707 (rank : 23)	θ value	1.38821 (rank : 29)
Query Neighborhood Hits	63	Target Neighborhood Hits	60	Shared Neighborhood Hits	12
SwissProt Accessions	P40937	Gene names	RFC5
Domain Architecture
Description	Replication factor C subunit 5 (Replication factor C 36 kDa subunit) (RF-C 36 kDa subunit) (RFC36) (Activator 1 36 kDa subunit) (A1 36 kDa subunit).

SPR2D_MOUSE
NC score	0.061973 (rank : 24)	θ value	θ > 10 (rank : 66)
Query Neighborhood Hits	63	Target Neighborhood Hits	61	Shared Neighborhood Hits	2
SwissProt Accessions	O70555	Gene names	Sprr2d
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2D.

SPR2F_HUMAN
NC score	0.060637 (rank : 25)	θ value	θ > 10 (rank : 68)
Query Neighborhood Hits	63	Target Neighborhood Hits	33	Shared Neighborhood Hits	2
SwissProt Accessions	Q96RM1	Gene names	SPRR2F
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2F (SPR-2F).

SPR2B_MOUSE
NC score	0.060461 (rank : 26)	θ value	θ > 10 (rank : 65)
Query Neighborhood Hits	63	Target Neighborhood Hits	51	Shared Neighborhood Hits	2
SwissProt Accessions	O70554, Q7TSB2	Gene names	Sprr2b
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2B.

SPR2G_MOUSE
NC score	0.060150 (rank : 27)	θ value	θ > 10 (rank : 69)
Query Neighborhood Hits	63	Target Neighborhood Hits	53	Shared Neighborhood Hits	2
SwissProt Accessions	O70558	Gene names	Sprr2g
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2G.

SPR2E_HUMAN
NC score	0.056560 (rank : 28)	θ value	θ > 10 (rank : 67)
Query Neighborhood Hits	63	Target Neighborhood Hits	32	Shared Neighborhood Hits	2
SwissProt Accessions	P22531, Q96RM2	Gene names	SPRR2E
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2E (SPR-2E) (Small proline-rich protein II) (SPR-II).

SPR2H_MOUSE
NC score	0.053769 (rank : 29)	θ value	θ > 10 (rank : 70)
Query Neighborhood Hits	63	Target Neighborhood Hits	82	Shared Neighborhood Hits	3
SwissProt Accessions	O70559	Gene names	Sprr2h
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2H.

STRC_HUMAN
NC score	0.040794 (rank : 30)	θ value	0.47712 (rank : 21)
Query Neighborhood Hits	63	Target Neighborhood Hits	32	Shared Neighborhood Hits	4
SwissProt Accessions	Q7RTU9	Gene names	STRC
Domain Architecture	No domain graphic available
Description	Stereocilin precursor.

ZN638_HUMAN
NC score	0.040046 (rank : 31)	θ value	1.06291 (rank : 26)
Query Neighborhood Hits	63	Target Neighborhood Hits	343	Shared Neighborhood Hits	8
SwissProt Accessions	Q14966, Q53R34, Q5XJ05, Q68DP3, Q6P2H2, Q7Z3T7, Q8NF92, Q8TCA1, Q9H2G1, Q9NP37	Gene names	ZNF638, NP220, ZFML
Domain Architecture	No domain graphic available
Description	Zinc finger protein 638 (Nuclear protein 220) (Zinc-finger matrin-like protein) (Cutaneous T-cell lymphoma-associated antigen se33-1) (CTCL tumor antigen se33-1).

ZN638_MOUSE
NC score	0.038436 (rank : 32)	θ value	1.06291 (rank : 27)
Query Neighborhood Hits	63	Target Neighborhood Hits	318	Shared Neighborhood Hits	5
SwissProt Accessions	Q61464, Q6DFV9, Q8C941	Gene names	Znf638, Np220, Zfml
Domain Architecture	No domain graphic available
Description	Zinc finger protein 638 (Nuclear protein 220) (Zinc-finger matrin-like protein).

NAGAB_MOUSE
NC score	0.034472 (rank : 33)	θ value	0.813845 (rank : 22)
Query Neighborhood Hits	63	Target Neighborhood Hits	6	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QWR8, O88620, Q8R437, Q8VDK2	Gene names	Naga
Domain Architecture	No domain graphic available
Description	Alpha-N-acetylgalactosaminidase precursor (EC 3.2.1.49) (Alpha- galactosidase B).

CIZ1_HUMAN
NC score	0.031403 (rank : 34)	θ value	2.36792 (rank : 34)
Query Neighborhood Hits	63	Target Neighborhood Hits	359	Shared Neighborhood Hits	7
SwissProt Accessions	Q9ULV3, Q9NYM8, Q9UHK4, Q9Y3F9, Q9Y3G0	Gene names	CIZ1, LSFR1, NP94
Domain Architecture	No domain graphic available
Description	Cip1-interacting zinc finger protein (Nuclear protein NP94).

CLIC6_HUMAN
NC score	0.028652 (rank : 35)	θ value	0.125558 (rank : 19)
Query Neighborhood Hits	63	Target Neighborhood Hits	289	Shared Neighborhood Hits	6
SwissProt Accessions	Q96NY7, Q8IX31	Gene names	CLIC6, CLIC1L
Domain Architecture	No domain graphic available
Description	Chloride intracellular channel 6.

STRC_MOUSE
NC score	0.028143 (rank : 36)	θ value	6.88961 (rank : 56)
Query Neighborhood Hits	63	Target Neighborhood Hits	89	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VIM6	Gene names	Strc
Domain Architecture	No domain graphic available
Description	Stereocilin precursor.

NEBU_HUMAN
NC score	0.025551 (rank : 37)	θ value	0.365318 (rank : 20)
Query Neighborhood Hits	63	Target Neighborhood Hits	420	Shared Neighborhood Hits	3
SwissProt Accessions	P20929, Q15346	Gene names	NEB
Domain Architecture
Description	Nebulin.

AKAP2_MOUSE
NC score	0.025505 (rank : 38)	θ value	2.36792 (rank : 32)
Query Neighborhood Hits	63	Target Neighborhood Hits	385	Shared Neighborhood Hits	6
SwissProt Accessions	O54931, O54932, O54933	Gene names	Akap2
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2) (AKAP expressed in kidney and lung) (AKAP-KL).

NAGAB_HUMAN
NC score	0.023577 (rank : 39)	θ value	6.88961 (rank : 54)
Query Neighborhood Hits	63	Target Neighborhood Hits	5	Shared Neighborhood Hits	3
SwissProt Accessions	P17050	Gene names	NAGA
Domain Architecture
Description	Alpha-N-acetylgalactosaminidase precursor (EC 3.2.1.49) (Alpha- galactosidase B).

MLL3_HUMAN
NC score	0.019805 (rank : 40)	θ value	3.0926 (rank : 38)
Query Neighborhood Hits	63	Target Neighborhood Hits	1644	Shared Neighborhood Hits	19
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

TNF10_MOUSE
NC score	0.019494 (rank : 41)	θ value	4.03905 (rank : 42)
Query Neighborhood Hits	63	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	P50592	Gene names	Tnfsf10, Trail
Domain Architecture
Description	Tumor necrosis factor ligand superfamily member 10 (TNF-related apoptosis-inducing ligand) (Protein TRAIL) (CD253 antigen).

AKAP2_HUMAN
NC score	0.019095 (rank : 42)	θ value	6.88961 (rank : 49)
Query Neighborhood Hits	63	Target Neighborhood Hits	507	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y2D5, Q9UG26	Gene names	AKAP2, KIAA0920
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2).

ZN622_MOUSE
NC score	0.018234 (rank : 43)	θ value	5.27518 (rank : 48)
Query Neighborhood Hits	63	Target Neighborhood Hits	28	Shared Neighborhood Hits	3
SwissProt Accessions	Q91VY9	Gene names	Znf622, D15Ertd806e, Zfp622
Domain Architecture	No domain graphic available
Description	Zinc finger protein 622.

TIF1B_MOUSE
NC score	0.016697 (rank : 44)	θ value	2.36792 (rank : 35)
Query Neighborhood Hits	63	Target Neighborhood Hits	276	Shared Neighborhood Hits	6
SwissProt Accessions	Q62318, P70391, Q8C283, Q99PN4	Gene names	Trim28, Krip1, Tif1b
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (KRAB-A-interacting protein) (KRIP-1).

ASAHL_HUMAN
NC score	0.016374 (rank : 45)	θ value	5.27518 (rank : 43)
Query Neighborhood Hits	63	Target Neighborhood Hits	6	Shared Neighborhood Hits	2
SwissProt Accessions	Q02083, Q5KTF2, Q96EY2, Q9BRA8	Gene names	ASAHL, NAAA, PLT
Domain Architecture
Description	N-acylethanolamine-hydrolyzing acid amidase precursor (EC 3.5.1.-) (N- acylsphingosine amidohydrolase-like) (ASAH-like protein) (Acid ceramidase-like protein).

ARMX5_MOUSE
NC score	0.016307 (rank : 46)	θ value	3.0926 (rank : 36)
Query Neighborhood Hits	63	Target Neighborhood Hits	46	Shared Neighborhood Hits	2
SwissProt Accessions	Q3UZB0	Gene names	Armcx5
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 5.

GCP5_HUMAN
NC score	0.016280 (rank : 47)	θ value	6.88961 (rank : 53)
Query Neighborhood Hits	63	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	Q96RT8, Q96PY8	Gene names	TUBGCP5, GCP5, KIAA1899
Domain Architecture
Description	Gamma-tubulin complex component 5 (GCP-5).

EPIPL_MOUSE
NC score	0.014312 (rank : 48)	θ value	3.0926 (rank : 37)
Query Neighborhood Hits	63	Target Neighborhood Hits	118	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R0W0	Gene names	Eppk1
Domain Architecture
Description	Epiplakin.

EDD1_MOUSE
NC score	0.014261 (rank : 49)	θ value	5.27518 (rank : 44)
Query Neighborhood Hits	63	Target Neighborhood Hits	167	Shared Neighborhood Hits	4
SwissProt Accessions	Q80TP3, Q698K9, Q6PEQ8, Q6PFQ9, Q80VL4, Q810V6, Q9CXE9	Gene names	Edd1, Edd, Kiaa0896
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog).

YETS2_HUMAN
NC score	0.013623 (rank : 50)	θ value	5.27518 (rank : 47)
Query Neighborhood Hits	63	Target Neighborhood Hits	212	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ULM3, Q641P6, Q9NW96	Gene names	YEATS2, KIAA1197
Domain Architecture	No domain graphic available
Description	YEATS domain-containing protein 2.

EDD1_HUMAN
NC score	0.013431 (rank : 51)	θ value	6.88961 (rank : 51)
Query Neighborhood Hits	63	Target Neighborhood Hits	170	Shared Neighborhood Hits	4
SwissProt Accessions	O95071, O94970, Q9NPL3	Gene names	EDD1, EDD, HYD, KIAA0896
Domain Architecture
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog) (hHYD) (Progestin-induced protein).

BRPF3_HUMAN
NC score	0.013120 (rank : 52)	θ value	2.36792 (rank : 33)
Query Neighborhood Hits	63	Target Neighborhood Hits	217	Shared Neighborhood Hits	5
SwissProt Accessions	Q9ULD4, Q5R3K8	Gene names	BRPF3, KIAA1286
Domain Architecture	No domain graphic available
Description	Bromodomain and PHD finger-containing protein 3.

TIF1A_MOUSE
NC score	0.012636 (rank : 53)	θ value	4.03905 (rank : 41)
Query Neighborhood Hits	63	Target Neighborhood Hits	307	Shared Neighborhood Hits	8
SwissProt Accessions	Q64127, Q64126	Gene names	Trim24, Tif1, Tif1a
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24).

GSHB_HUMAN
NC score	0.012414 (rank : 54)	θ value	8.99809 (rank : 59)
Query Neighborhood Hits	63	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	P48637, Q4TTD9	Gene names	GSS
Domain Architecture
Description	Glutathione synthetase (EC 6.3.2.3) (Glutathione synthase) (GSH synthetase) (GSH-S).

FBX32_HUMAN
NC score	0.011781 (rank : 55)	θ value	6.88961 (rank : 52)
Query Neighborhood Hits	63	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	Q969P5	Gene names	FBXO32
Domain Architecture	No domain graphic available
Description	F-box only protein 32 (Muscle atrophy F-box protein) (MAFbx) (Atrogin- 1).

FUT4_HUMAN
NC score	0.011280 (rank : 56)	θ value	5.27518 (rank : 46)
Query Neighborhood Hits	63	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	P22083	Gene names	FUT4, ELFT
Domain Architecture
Description	Alpha-(1,3)-fucosyltransferase (EC 2.4.1.-) (Galactoside 3-L- fucosyltransferase) (Fucosyltransferase 4) (FUCT-IV) (Fuc-TIV) (ELAM-1 ligand fucosyltransferase).

ITA2_MOUSE
NC score	0.010912 (rank : 57)	θ value	1.38821 (rank : 28)
Query Neighborhood Hits	63	Target Neighborhood Hits	70	Shared Neighborhood Hits	3
SwissProt Accessions	Q62469, Q62163	Gene names	Itga2
Domain Architecture
Description	Integrin alpha-2 precursor (Platelet membrane glycoprotein Ia) (GPIa) (Collagen receptor) (VLA-2 alpha chain) (CD49b antigen).

ATX2L_MOUSE
NC score	0.010493 (rank : 58)	θ value	8.99809 (rank : 58)
Query Neighborhood Hits	63	Target Neighborhood Hits	401	Shared Neighborhood Hits	6
SwissProt Accessions	Q7TQH0, Q80XN9, Q8K059	Gene names	Atxn2l, A2lp
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein.

AAKG3_MOUSE
NC score	0.008106 (rank : 59)	θ value	8.99809 (rank : 57)
Query Neighborhood Hits	63	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BGM7, Q80WK8, Q8CJ41	Gene names	Prkag3
Domain Architecture	No domain graphic available
Description	5'-AMP-activated protein kinase subunit gamma-3 (AMPK gamma-3 chain) (AMPK gamma3).

OGFR_HUMAN
NC score	0.007277 (rank : 60)	θ value	4.03905 (rank : 40)
Query Neighborhood Hits	63	Target Neighborhood Hits	1582	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

DDX51_HUMAN
NC score	0.005515 (rank : 61)	θ value	6.88961 (rank : 50)
Query Neighborhood Hits	63	Target Neighborhood Hits	332	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N8A6, Q5CZ71, Q8IXK5, Q96ED1	Gene names	DDX51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

SPTN2_HUMAN
NC score	0.003795 (rank : 62)	θ value	6.88961 (rank : 55)
Query Neighborhood Hits	63	Target Neighborhood Hits	535	Shared Neighborhood Hits	4
SwissProt Accessions	O15020, O14872, O14873	Gene names	SPTBN2, KIAA0302
Domain Architecture
Description	Spectrin beta chain, brain 2 (Spectrin, non-erythroid beta chain 2) (Beta-III spectrin).

ZN451_MOUSE
NC score	0.003312 (rank : 63)	θ value	8.99809 (rank : 63)
Query Neighborhood Hits	63	Target Neighborhood Hits	643	Shared Neighborhood Hits	5
SwissProt Accessions	Q8C0P7	Gene names	Znf451, Zfp451
Domain Architecture	No domain graphic available
Description	Zinc finger protein 451.

ZN142_HUMAN
NC score	0.002522 (rank : 64)	θ value	1.38821 (rank : 31)
Query Neighborhood Hits	63	Target Neighborhood Hits	1007	Shared Neighborhood Hits	13
SwissProt Accessions	P52746, Q92510	Gene names	ZNF142, KIAA0236
Domain Architecture	No domain graphic available
Description	Zinc finger protein 142 (HA4654).

SHAN1_HUMAN
NC score	0.002282 (rank : 65)	θ value	8.99809 (rank : 60)
Query Neighborhood Hits	63	Target Neighborhood Hits	1041	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

MAST4_HUMAN
NC score	0.002017 (rank : 66)	θ value	4.03905 (rank : 39)
Query Neighborhood Hits	63	Target Neighborhood Hits	1804	Shared Neighborhood Hits	9
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

FBN1_HUMAN
NC score	0.001926 (rank : 67)	θ value	5.27518 (rank : 45)
Query Neighborhood Hits	63	Target Neighborhood Hits	557	Shared Neighborhood Hits	2
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

WD51A_MOUSE
NC score	0.000945 (rank : 68)	θ value	8.99809 (rank : 61)
Query Neighborhood Hits	63	Target Neighborhood Hits	342	Shared Neighborhood Hits	2
SwissProt Accessions	Q8JZX3, Q9CY09	Gene names	Wdr51a
Domain Architecture	No domain graphic available
Description	WD repeat protein 51A.

ZN473_MOUSE
NC score	0.000746 (rank : 69)	θ value	1.06291 (rank : 25)
Query Neighborhood Hits	63	Target Neighborhood Hits	824	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BI67, Q8BI98, Q8BIB7	Gene names	Znf473, Zfp100, Zfp473
Domain Architecture	No domain graphic available
Description	Zinc finger protein 473 homolog (Zinc finger protein 100) (Zfp-100).

ZN174_HUMAN
NC score	-0.000752 (rank : 70)	θ value	8.99809 (rank : 62)
Query Neighborhood Hits	63	Target Neighborhood Hits	744	Shared Neighborhood Hits	5
SwissProt Accessions	Q15697, Q9BQ34	Gene names	ZNF174, ZSCAN8
Domain Architecture
Description	Zinc finger protein 174 (AW-1) (Zinc finger and SCAN domain-containing protein 8).