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Network neighborhood for query Sequence : KTNA1_MOUSE

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KTNA1_MOUSE
SwissProt Accessions	Q9WV86	Gene names	Katna1
Domain Architecture	No domain graphic available
Description	Katanin p60 ATPase-containing subunit A1 (EC 3.6.4.3) (Katanin p60 subunit A1) (p60 katanin) (Lipotransin).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

KTNA1_HUMAN
θ value	0 (rank : 1)	NC score	0.997142 (rank : 2)
Query Neighborhood Hits	123	Target Neighborhood Hits	117	Shared Neighborhood Hits	87
SwissProt Accessions	O75449, Q5TFA8, Q5TFA9, Q86VN2, Q9NU52	Gene names	KATNA1
Domain Architecture	No domain graphic available
Description	Katanin p60 ATPase-containing subunit A1 (EC 3.6.4.3) (Katanin p60 subunit A1) (p60 katanin).

KTNA1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	123	Target Neighborhood Hits	123	Shared Neighborhood Hits	123
SwissProt Accessions	Q9WV86	Gene names	Katna1
Domain Architecture	No domain graphic available
Description	Katanin p60 ATPase-containing subunit A1 (EC 3.6.4.3) (Katanin p60 subunit A1) (p60 katanin) (Lipotransin).

KATL1_HUMAN
θ value	1.19313e-177 (rank : 3)	NC score	0.993928 (rank : 4)
Query Neighborhood Hits	123	Target Neighborhood Hits	80	Shared Neighborhood Hits	67
SwissProt Accessions	Q9BW62	Gene names	KATNAL1
Domain Architecture	No domain graphic available
Description	Katanin p60 ATPase-containing subunit A-like 1 (EC 3.6.4.3) (Katanin p60 subunit A-like 1) (p60 katanin-like 1).

KATL1_MOUSE
θ value	1.31915e-176 (rank : 4)	NC score	0.994086 (rank : 3)
Query Neighborhood Hits	123	Target Neighborhood Hits	77	Shared Neighborhood Hits	67
SwissProt Accessions	Q8K0T4	Gene names	Katnal1
Domain Architecture	No domain graphic available
Description	Katanin p60 ATPase-containing subunit A-like 1 (EC 3.6.4.3) (Katanin p60 subunit A-like 1) (p60 katanin-like 1).

VPS4A_HUMAN
θ value	2.56992e-63 (rank : 5)	NC score	0.956185 (rank : 11)
Query Neighborhood Hits	123	Target Neighborhood Hits	95	Shared Neighborhood Hits	63
SwissProt Accessions	Q9UN37, Q8TF07, Q9UI03, Q9Y582	Gene names	VPS4A, VPS4
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associating protein 4A (SKD2 protein) (hVPS4) (VPS4-1).

VPS4A_MOUSE
θ value	2.56992e-63 (rank : 6)	NC score	0.956155 (rank : 12)
Query Neighborhood Hits	123	Target Neighborhood Hits	94	Shared Neighborhood Hits	63
SwissProt Accessions	Q8VEJ9, Q3TXT2	Gene names	Vps4a
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associating protein 4A.

SPAST_HUMAN
θ value	6.32992e-62 (rank : 7)	NC score	0.961189 (rank : 5)
Query Neighborhood Hits	123	Target Neighborhood Hits	100	Shared Neighborhood Hits	63
SwissProt Accessions	Q9UBP0, Q9UPR9	Gene names	SPAST, KIAA1083, SPG4
Domain Architecture
Description	Spastin.

SPAST_MOUSE
θ value	6.32992e-62 (rank : 8)	NC score	0.959766 (rank : 6)
Query Neighborhood Hits	123	Target Neighborhood Hits	138	Shared Neighborhood Hits	67
SwissProt Accessions	Q9QYY8, Q6ZPY6, Q80VE0, Q9CVK0	Gene names	Spast, Kiaa1083, Spg4
Domain Architecture	No domain graphic available
Description	Spastin.

VPS4B_MOUSE
θ value	1.41016e-61 (rank : 9)	NC score	0.957988 (rank : 10)
Query Neighborhood Hits	123	Target Neighborhood Hits	86	Shared Neighborhood Hits	62
SwissProt Accessions	P46467, Q91W22, Q9R1C9	Gene names	Vps4b, Skd1
Domain Architecture
Description	Vacuolar protein sorting-associating protein 4B (Protein SKD1).

VPS4B_HUMAN
θ value	4.10295e-61 (rank : 10)	NC score	0.958455 (rank : 9)
Query Neighborhood Hits	123	Target Neighborhood Hits	87	Shared Neighborhood Hits	63
SwissProt Accessions	O75351, Q9GZS7	Gene names	VPS4B, SKD1, VPS42
Domain Architecture
Description	Vacuolar protein sorting-associating protein 4B (Protein SKD1).

ATAD1_HUMAN
θ value	9.81109e-47 (rank : 11)	NC score	0.959189 (rank : 7)
Query Neighborhood Hits	123	Target Neighborhood Hits	75	Shared Neighborhood Hits	62
SwissProt Accessions	Q8NBU5, Q6P4B9, Q8N3G1, Q8WYR9, Q969Y3	Gene names	ATAD1
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 1.

ATAD1_MOUSE
θ value	9.81109e-47 (rank : 12)	NC score	0.959189 (rank : 8)
Query Neighborhood Hits	123	Target Neighborhood Hits	75	Shared Neighborhood Hits	62
SwissProt Accessions	Q9D5T0, Q3U8V2, Q9D7A4	Gene names	Atad1
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 1.

FIGN_MOUSE
θ value	3.72821e-46 (rank : 13)	NC score	0.926348 (rank : 17)
Query Neighborhood Hits	123	Target Neighborhood Hits	165	Shared Neighborhood Hits	56
SwissProt Accessions	Q9ERZ6, Q3TPB0, Q3UP57, Q6PCM0	Gene names	Fign
Domain Architecture	No domain graphic available
Description	Fidgetin.

FIGN_HUMAN
θ value	1.85029e-45 (rank : 14)	NC score	0.921935 (rank : 22)
Query Neighborhood Hits	123	Target Neighborhood Hits	176	Shared Neighborhood Hits	56
SwissProt Accessions	Q5HY92, Q9H6M5, Q9NVZ9	Gene names	FIGN
Domain Architecture	No domain graphic available
Description	Fidgetin.

TERA_HUMAN
θ value	6.58091e-43 (rank : 15)	NC score	0.927489 (rank : 13)
Query Neighborhood Hits	123	Target Neighborhood Hits	76	Shared Neighborhood Hits	65
SwissProt Accessions	P55072, Q969G7	Gene names	VCP
Domain Architecture
Description	Transitional endoplasmic reticulum ATPase (TER ATPase) (15S Mg(2+)- ATPase p97 subunit) (Valosin-containing protein) (VCP).

TERA_MOUSE
θ value	6.58091e-43 (rank : 16)	NC score	0.927447 (rank : 14)
Query Neighborhood Hits	123	Target Neighborhood Hits	76	Shared Neighborhood Hits	65
SwissProt Accessions	Q01853	Gene names	Vcp
Domain Architecture
Description	Transitional endoplasmic reticulum ATPase (TER ATPase) (15S Mg(2+)- ATPase p97 subunit) (Valosin-containing protein) (VCP).

PRS8_HUMAN
θ value	2.76489e-41 (rank : 17)	NC score	0.925077 (rank : 18)
Query Neighborhood Hits	123	Target Neighborhood Hits	117	Shared Neighborhood Hits	63
SwissProt Accessions	P62195, O35051, O43208, P47210, P52915, P52916	Gene names	PSMC5, SUG1
Domain Architecture
Description	26S protease regulatory subunit 8 (Proteasome 26S subunit ATPase 5) (Proteasome subunit p45) (p45/SUG) (Thyroid hormone receptor- interacting protein 1) (TRIP1).

PRS8_MOUSE
θ value	2.76489e-41 (rank : 18)	NC score	0.925077 (rank : 19)
Query Neighborhood Hits	123	Target Neighborhood Hits	117	Shared Neighborhood Hits	63
SwissProt Accessions	P62196, O35051, P47210, P52915, P52916, Q3UL51, Q9CWN5	Gene names	Psmc5, Sug1
Domain Architecture
Description	26S protease regulatory subunit 8 (Proteasome 26S subunit ATPase 5) (Proteasome subunit p45) (p45/SUG) (mSUG1).

PRS10_HUMAN
θ value	1.51715e-39 (rank : 19)	NC score	0.926819 (rank : 15)
Query Neighborhood Hits	123	Target Neighborhood Hits	95	Shared Neighborhood Hits	65
SwissProt Accessions	P62333, P49719, Q6IBU3, Q92524	Gene names	PSMC6, SUG2
Domain Architecture
Description	26S protease regulatory subunit S10B (Proteasome subunit p42) (Proteasome 26S subunit ATPase 6).

PRS10_MOUSE
θ value	1.51715e-39 (rank : 20)	NC score	0.926819 (rank : 16)
Query Neighborhood Hits	123	Target Neighborhood Hits	95	Shared Neighborhood Hits	65
SwissProt Accessions	P62334, P49719, Q3TKK1, Q810A6, Q92524, Q9CXH9	Gene names	Psmc6, Sug2
Domain Architecture
Description	26S protease regulatory subunit S10B (Proteasome subunit p42) (Proteasome 26S subunit ATPase 6).

PRS4_HUMAN
θ value	1.98146e-39 (rank : 21)	NC score	0.921292 (rank : 23)
Query Neighborhood Hits	123	Target Neighborhood Hits	84	Shared Neighborhood Hits	64
SwissProt Accessions	P62191, P49014, Q03527, Q6IAW0, Q96AZ3	Gene names	PSMC1
Domain Architecture
Description	26S protease regulatory subunit 4 (P26s4) (Proteasome 26S subunit ATPase 1).

PRS4_MOUSE
θ value	1.98146e-39 (rank : 22)	NC score	0.921292 (rank : 24)
Query Neighborhood Hits	123	Target Neighborhood Hits	84	Shared Neighborhood Hits	64
SwissProt Accessions	P62192, P49014, Q03527, Q96AZ3	Gene names	Psmc1
Domain Architecture
Description	26S protease regulatory subunit 4 (P26s4) (Proteasome 26S subunit ATPase 1).

NVL_MOUSE
θ value	3.37985e-39 (rank : 23)	NC score	0.917785 (rank : 26)
Query Neighborhood Hits	123	Target Neighborhood Hits	110	Shared Neighborhood Hits	66
SwissProt Accessions	Q9DBY8, Q3USC4, Q8BW27, Q8K2B5	Gene names	Nvl
Domain Architecture
Description	Nuclear valosin-containing protein-like (Nuclear VCP-like protein) (NVLp).

NVL_HUMAN
θ value	7.52953e-39 (rank : 24)	NC score	0.917151 (rank : 27)
Query Neighborhood Hits	123	Target Neighborhood Hits	112	Shared Neighborhood Hits	66
SwissProt Accessions	O15381, Q96EM7	Gene names	NVL
Domain Architecture
Description	Nuclear valosin-containing protein-like (Nuclear VCP-like protein) (NVLp).

PRS6A_HUMAN
θ value	8.32485e-38 (rank : 25)	NC score	0.922671 (rank : 21)
Query Neighborhood Hits	123	Target Neighborhood Hits	87	Shared Neighborhood Hits	59
SwissProt Accessions	P17980, Q96HD3	Gene names	PSMC3, TBP1
Domain Architecture
Description	26S protease regulatory subunit 6A (Proteasome 26S subunit ATPase 3) (TAT-binding protein 1) (TBP-1) (Proteasome subunit P50).

PRS6A_MOUSE
θ value	8.32485e-38 (rank : 26)	NC score	0.922854 (rank : 20)
Query Neighborhood Hits	123	Target Neighborhood Hits	85	Shared Neighborhood Hits	59
SwissProt Accessions	O88685	Gene names	Psmc3, Tbp1
Domain Architecture
Description	26S protease regulatory subunit 6A (Proteasome 26S subunit ATPase 3) (TAT-binding protein 1) (TBP-1).

PEX6_MOUSE
θ value	5.39604e-37 (rank : 27)	NC score	0.913375 (rank : 33)
Query Neighborhood Hits	123	Target Neighborhood Hits	94	Shared Neighborhood Hits	64
SwissProt Accessions	Q99LC9, Q6YNQ9	Gene names	Pex6
Domain Architecture	No domain graphic available
Description	Peroxisome assembly factor 2 (PAF-2) (Peroxisomal-type ATPase 1) (Peroxin-6) (Peroxisomal biogenesis factor 6).

PEX6_HUMAN
θ value	2.67802e-36 (rank : 28)	NC score	0.913518 (rank : 32)
Query Neighborhood Hits	123	Target Neighborhood Hits	99	Shared Neighborhood Hits	65
SwissProt Accessions	Q13608, Q8WYQ2, Q99476	Gene names	PEX6, PXAAA1
Domain Architecture
Description	Peroxisome assembly factor 2 (PAF-2) (Peroxisomal-type ATPase 1) (Peroxin-6) (Peroxisomal biogenesis factor 6).

PEX1_HUMAN
θ value	2.12192e-33 (rank : 29)	NC score	0.919690 (rank : 25)
Query Neighborhood Hits	123	Target Neighborhood Hits	98	Shared Neighborhood Hits	62
SwissProt Accessions	O43933, Q96S71, Q96S72, Q96S73, Q99994	Gene names	PEX1
Domain Architecture
Description	Peroxisome biogenesis factor 1 (Peroxin-1) (Peroxisome biogenesis disorder protein 1).

YMEL1_MOUSE
θ value	2.12192e-33 (rank : 30)	NC score	0.901291 (rank : 34)
Query Neighborhood Hits	123	Target Neighborhood Hits	76	Shared Neighborhood Hits	60
SwissProt Accessions	O88967, Q7TNN5	Gene names	Yme1l1
Domain Architecture
Description	ATP-dependent metalloprotease YME1L1 (EC 3.4.24.-) (YME1-like protein 1) (ATP-dependent metalloprotease FtsH1).

AFG31_MOUSE
θ value	1.37539e-32 (rank : 31)	NC score	0.896499 (rank : 36)
Query Neighborhood Hits	123	Target Neighborhood Hits	74	Shared Neighborhood Hits	62
SwissProt Accessions	Q920A7	Gene names	Afg3l1
Domain Architecture
Description	AFG3-like protein 1 (EC 3.4.24.-).

PRS7_HUMAN
θ value	4.00176e-32 (rank : 32)	NC score	0.916733 (rank : 28)
Query Neighborhood Hits	123	Target Neighborhood Hits	66	Shared Neighborhood Hits	61
SwissProt Accessions	P35998	Gene names	PSMC2, MSS1
Domain Architecture
Description	26S protease regulatory subunit 7 (Proteasome 26S subunit ATPase 2) (Protein MSS1).

PRS7_MOUSE
θ value	4.00176e-32 (rank : 33)	NC score	0.916724 (rank : 29)
Query Neighborhood Hits	123	Target Neighborhood Hits	67	Shared Neighborhood Hits	61
SwissProt Accessions	P46471, O08531, Q3TGX5, Q9DBA1	Gene names	Psmc2, Mss1
Domain Architecture
Description	26S protease regulatory subunit 7 (Proteasome 26S subunit ATPase 2) (Protein MSS1).

ATAD2_HUMAN
θ value	8.91499e-32 (rank : 34)	NC score	0.851530 (rank : 43)
Query Neighborhood Hits	123	Target Neighborhood Hits	322	Shared Neighborhood Hits	64
SwissProt Accessions	Q6PL18, Q658P2, Q68CQ0, Q6PJV6, Q8N890, Q9UHS5	Gene names	ATAD2
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 2.

PRS6B_HUMAN
θ value	1.16434e-31 (rank : 35)	NC score	0.915946 (rank : 30)
Query Neighborhood Hits	123	Target Neighborhood Hits	85	Shared Neighborhood Hits	57
SwissProt Accessions	P43686, Q96FV5, Q9UBM3, Q9UEX3	Gene names	PSMC4, TBP7
Domain Architecture
Description	26S protease regulatory subunit 6B (Proteasome 26S subunit ATPase 4) (MIP224) (MB67-interacting protein) (TAT-binding protein 7) (TBP-7).

ATAD2_MOUSE
θ value	1.98606e-31 (rank : 36)	NC score	0.868947 (rank : 42)
Query Neighborhood Hits	123	Target Neighborhood Hits	167	Shared Neighborhood Hits	62
SwissProt Accessions	Q8CDM1	Gene names	Atad2
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 2.

PRS6B_MOUSE
θ value	5.77852e-31 (rank : 37)	NC score	0.914773 (rank : 31)
Query Neighborhood Hits	123	Target Neighborhood Hits	89	Shared Neighborhood Hits	57
SwissProt Accessions	P54775	Gene names	Psmc4, Tbp7
Domain Architecture
Description	26S protease regulatory subunit 6B (Proteasome 26S subunit ATPase 4) (MIP224) (MB67-interacting protein) (TAT-binding protein 7) (TBP-7) (CIP21).

AFG32_HUMAN
θ value	2.19584e-30 (rank : 38)	NC score	0.890656 (rank : 38)
Query Neighborhood Hits	123	Target Neighborhood Hits	72	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Y4W6	Gene names	AFG3L2
Domain Architecture
Description	AFG3-like protein 2 (EC 3.4.24.-) (Paraplegin-like protein).

AFG32_MOUSE
θ value	2.86786e-30 (rank : 39)	NC score	0.890492 (rank : 39)
Query Neighborhood Hits	123	Target Neighborhood Hits	73	Shared Neighborhood Hits	62
SwissProt Accessions	Q8JZQ2	Gene names	Afg3l2
Domain Architecture	No domain graphic available
Description	AFG3-like protein 2 (EC 3.4.24.-).

YMEL1_HUMAN
θ value	1.4233e-29 (rank : 40)	NC score	0.897769 (rank : 35)
Query Neighborhood Hits	123	Target Neighborhood Hits	73	Shared Neighborhood Hits	60
SwissProt Accessions	Q96TA2, Q9H1Q0, Q9UMR9	Gene names	YME1L1, FTSH1, YME1L
Domain Architecture
Description	ATP-dependent metalloprotease YME1L1 (EC 3.4.24.-) (YME1-like protein 1) (ATP-dependent metalloprotease FtsH1) (Meg-4) (Presenilin- associated metalloprotease) (PAMP).

SPG7_HUMAN
θ value	3.17079e-29 (rank : 41)	NC score	0.896205 (rank : 37)
Query Neighborhood Hits	123	Target Neighborhood Hits	71	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UQ90, O75756, Q96IB0	Gene names	SPG7, CAR, CMAR, PGN
Domain Architecture
Description	Paraplegin (EC 3.4.24.-) (Spastic paraplegia protein 7).

NSF_HUMAN
θ value	3.75424e-22 (rank : 42)	NC score	0.876233 (rank : 40)
Query Neighborhood Hits	123	Target Neighborhood Hits	74	Shared Neighborhood Hits	64
SwissProt Accessions	P46459, Q9UKZ2	Gene names	NSF
Domain Architecture
Description	Vesicle-fusing ATPase (EC 3.6.4.6) (Vesicular-fusion protein NSF) (N- ethylmaleimide sensitive fusion protein) (NEM-sensitive fusion protein).

NSF_MOUSE
θ value	3.75424e-22 (rank : 43)	NC score	0.875738 (rank : 41)
Query Neighborhood Hits	123	Target Neighborhood Hits	73	Shared Neighborhood Hits	61
SwissProt Accessions	P46460	Gene names	Nsf, Skd2
Domain Architecture
Description	Vesicle-fusing ATPase (EC 3.6.4.6) (Vesicular-fusion protein NSF) (N- ethylmaleimide sensitive fusion protein) (NEM-sensitive fusion protein) (SKD2 protein).

ATD3B_HUMAN
θ value	2.79066e-09 (rank : 44)	NC score	0.622660 (rank : 47)
Query Neighborhood Hits	123	Target Neighborhood Hits	340	Shared Neighborhood Hits	60
SwissProt Accessions	Q5T9A4, Q6ZRB5, Q9BUK4, Q9ULE7	Gene names	ATAD3B, KIAA1273
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 3B.

ATAD3_MOUSE
θ value	1.80886e-08 (rank : 45)	NC score	0.614020 (rank : 48)
Query Neighborhood Hits	123	Target Neighborhood Hits	326	Shared Neighborhood Hits	63
SwissProt Accessions	Q925I1, Q3UE74, Q69ZM7, Q8C6C6	Gene names	Atad3, Atad3a, Kiaa1273
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 3 (AAA-ATPase TOB3).

ATD3A_HUMAN
θ value	1.80886e-08 (rank : 46)	NC score	0.638257 (rank : 46)
Query Neighborhood Hits	123	Target Neighborhood Hits	248	Shared Neighborhood Hits	64
SwissProt Accessions	Q9NVI7, Q8N275, Q96A50	Gene names	ATAD3A
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 3A.

TRP13_MOUSE
θ value	1.80886e-08 (rank : 47)	NC score	0.713959 (rank : 44)
Query Neighborhood Hits	123	Target Neighborhood Hits	81	Shared Neighborhood Hits	58
SwissProt Accessions	Q3UA06, Q3UQG6, Q9CWW8	Gene names	Trip13
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 13 (Thyroid hormone receptor interactor 13) (Trip-13).

TRP13_HUMAN
θ value	3.08544e-08 (rank : 48)	NC score	0.712445 (rank : 45)
Query Neighborhood Hits	123	Target Neighborhood Hits	81	Shared Neighborhood Hits	59
SwissProt Accessions	Q15645, O15324	Gene names	TRIP13
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 13 (Thyroid hormone receptor interactor 13) (Trip-13) (Human papillomavirus type 16 E1 protein- binding protein) (HPV16 E1 protein-binding protein) (16E1-BP).

CLPX_HUMAN
θ value	0.00509761 (rank : 49)	NC score	0.425665 (rank : 51)
Query Neighborhood Hits	123	Target Neighborhood Hits	72	Shared Neighborhood Hits	51
SwissProt Accessions	O76031, Q9H4D9	Gene names	CLPX
Domain Architecture
Description	ATP-dependent Clp protease ATP-binding subunit ClpX-like, mitochondrial precursor.

CLPX_MOUSE
θ value	0.00509761 (rank : 50)	NC score	0.422852 (rank : 52)
Query Neighborhood Hits	123	Target Neighborhood Hits	73	Shared Neighborhood Hits	51
SwissProt Accessions	Q9JHS4, Q9WVD1	Gene names	Clpx
Domain Architecture
Description	ATP-dependent Clp protease ATP-binding subunit ClpX-like, mitochondrial precursor.

LIMA1_MOUSE
θ value	0.0113563 (rank : 51)	NC score	0.025879 (rank : 75)
Query Neighborhood Hits	123	Target Neighborhood Hits	298	Shared Neighborhood Hits	8
SwissProt Accessions	Q9ERG0, Q9ERG1	Gene names	Lima1, D15Ertd366e, Eplin
Domain Architecture
Description	LIM domain and actin-binding protein 1 (Epithelial protein lost in neoplasm) (mEPLIN).

FOXM1_HUMAN
θ value	0.0252991 (rank : 52)	NC score	0.020471 (rank : 78)
Query Neighborhood Hits	123	Target Neighborhood Hits	167	Shared Neighborhood Hits	7
SwissProt Accessions	Q08050, O43258, O43259, O43260, Q4ZGG7, Q9BRL2	Gene names	FOXM1, FKHL16, HFH11, MPP2, WIN
Domain Architecture
Description	Forkhead box protein M1 (Forkhead-related protein FKHL16) (Hepatocyte nuclear factor 3 forkhead homolog 11) (HNF-3/fork-head homolog 11) (HFH-11) (Winged helix factor from INS-1 cells) (M-phase phosphoprotein 2) (MPM-2 reactive phosphoprotein 2) (Transcription factor Trident).

RUVB1_HUMAN
θ value	0.0563607 (rank : 53)	NC score	0.324473 (rank : 54)
Query Neighborhood Hits	123	Target Neighborhood Hits	78	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Y265, Q9BSX9	Gene names	RUVBL1, NMP238, TIP49, TIP49A
Domain Architecture
Description	RuvB-like 1 (EC 3.6.1.-) (49 kDa TATA box-binding protein-interacting protein) (49 kDa TBP-interacting protein) (TIP49a) (Pontin 52) (Nuclear matrix protein 238) (NMP 238) (54 kDa erythrocyte cytosolic protein) (ECP-54) (TIP60-associated protein 54-alpha) (TAP54-alpha).

RUVB1_MOUSE
θ value	0.0563607 (rank : 54)	NC score	0.324434 (rank : 55)
Query Neighborhood Hits	123	Target Neighborhood Hits	78	Shared Neighborhood Hits	59
SwissProt Accessions	P60122, O35753	Gene names	Ruvbl1, Tip49, Tip49a
Domain Architecture
Description	RuvB-like 1 (EC 3.6.1.-) (49 kDa TATA box-binding protein-interacting protein) (49 kDa TBP-interacting protein) (TIP49a) (Pontin 52) (DNA helicase p50).

BANK1_MOUSE
θ value	0.125558 (rank : 55)	NC score	0.038822 (rank : 71)
Query Neighborhood Hits	123	Target Neighborhood Hits	63	Shared Neighborhood Hits	6
SwissProt Accessions	Q80VH0, Q3U178, Q8BRV6, Q8BRY8	Gene names	Bank1
Domain Architecture	No domain graphic available
Description	B-cell scaffold protein with ankyrin repeats (Protein AVIEF).

LONM_HUMAN
θ value	0.125558 (rank : 56)	NC score	0.413642 (rank : 53)
Query Neighborhood Hits	123	Target Neighborhood Hits	130	Shared Neighborhood Hits	58
SwissProt Accessions	P36776, P36777, Q9UQ95	Gene names	PRSS15
Domain Architecture
Description	Lon protease homolog, mitochondrial precursor (EC 3.4.21.-) (Lon protease-like protein) (LONP) (LONHs).

CIR_MOUSE
θ value	0.21417 (rank : 57)	NC score	0.031967 (rank : 73)
Query Neighborhood Hits	123	Target Neighborhood Hits	255	Shared Neighborhood Hits	10
SwissProt Accessions	Q9DA19, Q3V2N9, Q4KL44, Q52KL9, Q5FW66	Gene names	Cir
Domain Architecture	No domain graphic available
Description	CBF1-interacting corepressor.

SYYM_MOUSE
θ value	0.21417 (rank : 58)	NC score	0.030369 (rank : 74)
Query Neighborhood Hits	123	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BYL4, Q6PAH7	Gene names	Yars2
Domain Architecture	No domain graphic available
Description	Tyrosyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.1) (Tyrosine--tRNA ligase) (TyrRS).

CHD3_HUMAN
θ value	0.365318 (rank : 59)	NC score	0.008704 (rank : 96)
Query Neighborhood Hits	123	Target Neighborhood Hits	397	Shared Neighborhood Hits	8
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

TITIN_HUMAN
θ value	0.365318 (rank : 60)	NC score	-0.004121 (rank : 123)
Query Neighborhood Hits	123	Target Neighborhood Hits	2923	Shared Neighborhood Hits	25
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

BANK1_HUMAN
θ value	0.47712 (rank : 61)	NC score	0.032564 (rank : 72)
Query Neighborhood Hits	123	Target Neighborhood Hits	44	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NDB2, Q8N5K8, Q8NB56, Q8WYN5, Q9NWP2	Gene names	BANK1
Domain Architecture	No domain graphic available
Description	B-cell scaffold protein with ankyrin repeats.

CAC1B_MOUSE
θ value	0.47712 (rank : 62)	NC score	0.009474 (rank : 93)
Query Neighborhood Hits	123	Target Neighborhood Hits	351	Shared Neighborhood Hits	7
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

WRIP1_HUMAN
θ value	0.47712 (rank : 63)	NC score	0.230738 (rank : 56)
Query Neighborhood Hits	123	Target Neighborhood Hits	100	Shared Neighborhood Hits	51
SwissProt Accessions	Q96S55, Q53EP6, Q59ET8, Q5W0E2, Q5W0E4, Q8WV26, Q9H681, Q9NRJ6	Gene names	WRNIP1, WHIP
Domain Architecture	No domain graphic available
Description	ATPase WRNIP1 (Werner helicase-interacting protein 1).

SFR12_HUMAN
θ value	0.62314 (rank : 64)	NC score	0.013185 (rank : 86)
Query Neighborhood Hits	123	Target Neighborhood Hits	553	Shared Neighborhood Hits	11
SwissProt Accessions	Q8WXA9, Q86X37	Gene names	SFRS12, SRRP86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86) (Splicing regulatory protein 508) (SRrp508).

SRRM2_HUMAN
θ value	0.62314 (rank : 65)	NC score	0.014807 (rank : 82)
Query Neighborhood Hits	123	Target Neighborhood Hits	1296	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

THNSL_MOUSE
θ value	0.62314 (rank : 66)	NC score	0.131743 (rank : 58)
Query Neighborhood Hits	123	Target Neighborhood Hits	47	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BH55	Gene names	Thnsl1
Domain Architecture	No domain graphic available
Description	Threonine synthase-like 1.

WRIP1_MOUSE
θ value	0.62314 (rank : 67)	NC score	0.229241 (rank : 57)
Query Neighborhood Hits	123	Target Neighborhood Hits	93	Shared Neighborhood Hits	52
SwissProt Accessions	Q91XU0, Q3TCT7, Q6PDF0, Q8BUW5, Q8BWP6, Q8BY55, Q921W3, Q9EQL3	Gene names	Wrnip1, Whip
Domain Architecture	No domain graphic available
Description	ATPase WRNIP1 (Werner helicase-interacting protein 1).

CTCF_HUMAN
θ value	0.813845 (rank : 68)	NC score	-0.004244 (rank : 124)
Query Neighborhood Hits	123	Target Neighborhood Hits	764	Shared Neighborhood Hits	5
SwissProt Accessions	P49711	Gene names	CTCF
Domain Architecture
Description	Transcriptional repressor CTCF (CCCTC-binding factor) (CTCFL paralog) (11-zinc finger protein).

RFC4_HUMAN
θ value	0.813845 (rank : 69)	NC score	0.108797 (rank : 64)
Query Neighborhood Hits	123	Target Neighborhood Hits	64	Shared Neighborhood Hits	38
SwissProt Accessions	P35249, Q6FHX7	Gene names	RFC4
Domain Architecture
Description	Replication factor C subunit 4 (Replication factor C 37 kDa subunit) (RF-C 37 kDa subunit) (RFC37) (Activator 1 37 kDa subunit) (A1 37 kDa subunit).

SAHH3_HUMAN
θ value	0.813845 (rank : 70)	NC score	0.012748 (rank : 87)
Query Neighborhood Hits	123	Target Neighborhood Hits	23	Shared Neighborhood Hits	4
SwissProt Accessions	Q96HN2, O94917	Gene names	KIAA0828
Domain Architecture
Description	Putative adenosylhomocysteinase 3 (EC 3.3.1.1) (S-adenosyl-L- homocysteine hydrolase 3) (AdoHcyase 3).

IMUP_HUMAN
θ value	1.06291 (rank : 71)	NC score	0.071806 (rank : 68)
Query Neighborhood Hits	123	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	Q9GZP8, Q96H58, Q9HCR4	Gene names	IMUP, C19orf33
Domain Architecture	No domain graphic available
Description	Immortalization-up-regulated protein (Hepatocyte growth factor activator inhibitor type 2-related small protein) (HAI-2-related small protein) (H2RSP).

TAF3_HUMAN
θ value	1.06291 (rank : 72)	NC score	0.011684 (rank : 89)
Query Neighborhood Hits	123	Target Neighborhood Hits	568	Shared Neighborhood Hits	14
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

TM131_MOUSE
θ value	1.06291 (rank : 73)	NC score	0.018468 (rank : 79)
Query Neighborhood Hits	123	Target Neighborhood Hits	156	Shared Neighborhood Hits	5
SwissProt Accessions	O70472	Gene names	Tmem131, D1Bwg0491e, Rw1
Domain Architecture	No domain graphic available
Description	Transmembrane protein 131 (Protein RW1).

PO6F2_MOUSE
θ value	1.38821 (rank : 74)	NC score	0.002327 (rank : 115)
Query Neighborhood Hits	123	Target Neighborhood Hits	639	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BJI4	Gene names	Pou6f2
Domain Architecture	No domain graphic available
Description	POU domain, class 6, transcription factor 2.

RFC1_HUMAN
θ value	1.38821 (rank : 75)	NC score	0.120103 (rank : 62)
Query Neighborhood Hits	123	Target Neighborhood Hits	352	Shared Neighborhood Hits	51
SwissProt Accessions	P35251, Q5XKF5, Q6PKU0, Q86V41, Q86V46	Gene names	RFC1, RFC140
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (DNA-binding protein PO-GA).

RFC1_MOUSE
θ value	1.38821 (rank : 76)	NC score	0.131007 (rank : 59)
Query Neighborhood Hits	123	Target Neighborhood Hits	290	Shared Neighborhood Hits	53
SwissProt Accessions	P35601	Gene names	Rfc1, Ibf-1, Recc1
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (A1-P145) (Differentiation- specific element-binding protein) (ISRE-binding protein).

MAGI1_MOUSE
θ value	1.81305 (rank : 77)	NC score	0.003376 (rank : 112)
Query Neighborhood Hits	123	Target Neighborhood Hits	403	Shared Neighborhood Hits	11
SwissProt Accessions	Q6RHR9, O54893, O54894, O54895	Gene names	Magi1, Baiap1, Bap1
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1).

THOC2_HUMAN
θ value	1.81305 (rank : 78)	NC score	0.020650 (rank : 77)
Query Neighborhood Hits	123	Target Neighborhood Hits	337	Shared Neighborhood Hits	11
SwissProt Accessions	Q8NI27, Q9H8I6	Gene names	THOC2, CXorf3
Domain Architecture	No domain graphic available
Description	THO complex subunit 2 (Tho2).

APC_MOUSE
θ value	2.36792 (rank : 79)	NC score	0.009745 (rank : 91)
Query Neighborhood Hits	123	Target Neighborhood Hits	441	Shared Neighborhood Hits	7
SwissProt Accessions	Q61315, Q62044	Gene names	Apc
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC) (mAPC).

MAP4_HUMAN
θ value	2.36792 (rank : 80)	NC score	0.016057 (rank : 81)
Query Neighborhood Hits	123	Target Neighborhood Hits	428	Shared Neighborhood Hits	13
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

RFC4_MOUSE
θ value	2.36792 (rank : 81)	NC score	0.097165 (rank : 66)
Query Neighborhood Hits	123	Target Neighborhood Hits	65	Shared Neighborhood Hits	38
SwissProt Accessions	Q99J62	Gene names	Rfc4
Domain Architecture	No domain graphic available
Description	Replication factor C subunit 4.

THNSL_HUMAN
θ value	2.36792 (rank : 82)	NC score	0.119957 (rank : 63)
Query Neighborhood Hits	123	Target Neighborhood Hits	47	Shared Neighborhood Hits	36
SwissProt Accessions	Q8IYQ7, Q5VV21	Gene names	THNSL1
Domain Architecture	No domain graphic available
Description	Threonine synthase-like 1.

AP3D1_HUMAN
θ value	3.0926 (rank : 83)	NC score	0.005742 (rank : 104)
Query Neighborhood Hits	123	Target Neighborhood Hits	254	Shared Neighborhood Hits	5
SwissProt Accessions	O14617, O00202, O75262, Q59HF5, Q96G11, Q9H3C6	Gene names	AP3D1
Domain Architecture
Description	AP-3 complex subunit delta-1 (Adapter-related protein complex 3 subunit delta-1) (Delta-adaptin 3) (AP-3 complex subunit delta) (Delta-adaptin).

M4K4_HUMAN
θ value	3.0926 (rank : 84)	NC score	-0.005119 (rank : 125)
Query Neighborhood Hits	123	Target Neighborhood Hits	1589	Shared Neighborhood Hits	12
SwissProt Accessions	O95819, O75172, Q9NST7	Gene names	MAP4K4, HGK, KIAA0687, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

SMBP2_MOUSE
θ value	3.0926 (rank : 85)	NC score	0.018451 (rank : 80)
Query Neighborhood Hits	123	Target Neighborhood Hits	104	Shared Neighborhood Hits	7
SwissProt Accessions	P40694	Gene names	Ighmbp2, Smbp-2, Smbp2
Domain Architecture
Description	DNA-binding protein SMUBP-2 (EC 3.6.1.-) (ATP-dependent helicase IGHMBP2) (Immunoglobulin mu-binding protein 2) (SMUBP-2) (Cardiac transcription factor 1) (CATF1).

STK6_HUMAN
θ value	3.0926 (rank : 86)	NC score	-0.005186 (rank : 126)
Query Neighborhood Hits	123	Target Neighborhood Hits	916	Shared Neighborhood Hits	8
SwissProt Accessions	O14965, O60445, O75873, Q9BQD6, Q9UPG5	Gene names	STK6, AIK, ARK1, AURA, BTAK, STK15
Domain Architecture
Description	Serine/threonine-protein kinase 6 (EC 2.7.11.1) (Serine/threonine kinase 15) (Aurora/IPL1-related kinase 1) (Aurora-related kinase 1) (hARK1) (Aurora-A) (Breast-tumor-amplified kinase).

SYYM_HUMAN
θ value	3.0926 (rank : 87)	NC score	0.023580 (rank : 76)
Query Neighborhood Hits	123	Target Neighborhood Hits	5	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y2Z4, Q9H817	Gene names	YARS2
Domain Architecture	No domain graphic available
Description	Tyrosyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.1) (Tyrosine--tRNA ligase) (TyrRS).

AFF4_HUMAN
θ value	4.03905 (rank : 88)	NC score	0.006995 (rank : 100)
Query Neighborhood Hits	123	Target Neighborhood Hits	611	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

BCS1_HUMAN
θ value	4.03905 (rank : 89)	NC score	0.570372 (rank : 49)
Query Neighborhood Hits	123	Target Neighborhood Hits	61	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Y276, Q7Z2V7	Gene names	BCS1L, BCS1
Domain Architecture
Description	Mitochondrial chaperone BCS1 (BCS1-like protein) (H-BCS1).

RTKN_MOUSE
θ value	4.03905 (rank : 90)	NC score	0.014788 (rank : 83)
Query Neighborhood Hits	123	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C6B2, Q61192, Q8VIG7	Gene names	Rtkn
Domain Architecture	No domain graphic available
Description	Rhotekin.

SRRM1_HUMAN
θ value	4.03905 (rank : 91)	NC score	0.011612 (rank : 90)
Query Neighborhood Hits	123	Target Neighborhood Hits	690	Shared Neighborhood Hits	15
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

TGM5_MOUSE
θ value	4.03905 (rank : 92)	NC score	0.003603 (rank : 111)
Query Neighborhood Hits	123	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D7I9, Q3V1F9	Gene names	Tgm5
Domain Architecture	No domain graphic available
Description	Protein-glutamine gamma-glutamyltransferase 5 (EC 2.3.2.13) (Transglutaminase-5) (TGase 5).

TSH1_MOUSE
θ value	4.03905 (rank : 93)	NC score	0.006147 (rank : 103)
Query Neighborhood Hits	123	Target Neighborhood Hits	675	Shared Neighborhood Hits	11
SwissProt Accessions	Q5DTH5, Q6PE60, Q8VD19, Q9JLD5	Gene names	Tshz1, Kiaa4206, Sdccag33, Tsh1
Domain Architecture	No domain graphic available
Description	Teashirt homolog 1 (Serologically defined colon cancer antigen 3 homolog).

UTRO_HUMAN
θ value	4.03905 (rank : 94)	NC score	-0.000556 (rank : 120)
Query Neighborhood Hits	123	Target Neighborhood Hits	960	Shared Neighborhood Hits	8
SwissProt Accessions	P46939	Gene names	UTRN, DMDL
Domain Architecture
Description	Utrophin (Dystrophin-related protein 1) (DRP1) (DRP).

BARX2_MOUSE
θ value	5.27518 (rank : 95)	NC score	-0.000016 (rank : 118)
Query Neighborhood Hits	123	Target Neighborhood Hits	335	Shared Neighborhood Hits	5
SwissProt Accessions	O08686	Gene names	Barx2
Domain Architecture
Description	Homeobox protein BarH-like 2.

CPXM2_HUMAN
θ value	5.27518 (rank : 96)	NC score	0.002165 (rank : 116)
Query Neighborhood Hits	123	Target Neighborhood Hits	84	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N436	Gene names	CPXM2
Domain Architecture
Description	Carboxypeptidase-like protein X2 precursor.

DYH5_HUMAN
θ value	5.27518 (rank : 97)	NC score	0.009203 (rank : 94)
Query Neighborhood Hits	123	Target Neighborhood Hits	323	Shared Neighborhood Hits	10
SwissProt Accessions	Q8TE73, Q92860, Q96L74, Q9H5S7, Q9HCG9	Gene names	DNAH5, DNAHC5, KIAA1603
Domain Architecture	No domain graphic available
Description	Ciliary dynein heavy chain 5 (Axonemal beta dynein heavy chain 5) (HL1).

FA44A_HUMAN
θ value	5.27518 (rank : 98)	NC score	0.007605 (rank : 98)
Query Neighborhood Hits	123	Target Neighborhood Hits	280	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NFC6, Q6P0M8	Gene names	FAM44A
Domain Architecture	No domain graphic available
Description	Protein FAM44A.

MAP1B_HUMAN
θ value	5.27518 (rank : 99)	NC score	0.004005 (rank : 109)
Query Neighborhood Hits	123	Target Neighborhood Hits	903	Shared Neighborhood Hits	19
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

SF01_HUMAN
θ value	5.27518 (rank : 100)	NC score	0.007575 (rank : 99)
Query Neighborhood Hits	123	Target Neighborhood Hits	287	Shared Neighborhood Hits	5
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

SRRM2_MOUSE
θ value	5.27518 (rank : 101)	NC score	0.014711 (rank : 84)
Query Neighborhood Hits	123	Target Neighborhood Hits	1470	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

BCS1_MOUSE
θ value	6.88961 (rank : 102)	NC score	0.559813 (rank : 50)
Query Neighborhood Hits	123	Target Neighborhood Hits	64	Shared Neighborhood Hits	52
SwissProt Accessions	Q9CZP5	Gene names	Bcs1l
Domain Architecture
Description	Mitochondrial chaperone BCS1 (BCS1-like protein).

BRD4_MOUSE
θ value	6.88961 (rank : 103)	NC score	0.014262 (rank : 85)
Query Neighborhood Hits	123	Target Neighborhood Hits	845	Shared Neighborhood Hits	12
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

CBLB_MOUSE
θ value	6.88961 (rank : 104)	NC score	0.004919 (rank : 107)
Query Neighborhood Hits	123	Target Neighborhood Hits	277	Shared Neighborhood Hits	4
SwissProt Accessions	Q3TTA7	Gene names	Cblb
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b).

GIT1_HUMAN
θ value	6.88961 (rank : 105)	NC score	0.000293 (rank : 117)
Query Neighborhood Hits	123	Target Neighborhood Hits	336	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y2X7, Q86SS0, Q9BRJ4	Gene names	GIT1
Domain Architecture
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1) (Cool-associated and tyrosine-phosphorylated protein 1) (Cat-1).

K0427_HUMAN
θ value	6.88961 (rank : 106)	NC score	0.006312 (rank : 101)
Query Neighborhood Hits	123	Target Neighborhood Hits	55	Shared Neighborhood Hits	3
SwissProt Accessions	O43310, Q8IVD5	Gene names	KIAA0427
Domain Architecture	No domain graphic available
Description	Protein KIAA0427.

MYH10_HUMAN
θ value	6.88961 (rank : 107)	NC score	-0.003399 (rank : 121)
Query Neighborhood Hits	123	Target Neighborhood Hits	1620	Shared Neighborhood Hits	18
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

PRP4B_HUMAN
θ value	6.88961 (rank : 108)	NC score	-0.004073 (rank : 122)
Query Neighborhood Hits	123	Target Neighborhood Hits	1030	Shared Neighborhood Hits	13
SwissProt Accessions	Q13523, Q8TDP2, Q96QT7, Q9UEE6	Gene names	PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (PRP4 kinase).

RU17_HUMAN
θ value	6.88961 (rank : 109)	NC score	0.002883 (rank : 114)
Query Neighborhood Hits	123	Target Neighborhood Hits	280	Shared Neighborhood Hits	3
SwissProt Accessions	P08621, P78493, P78494, Q15364, Q15686, Q15687, Q15689, Q99377, Q9UE45, Q9UE46, Q9UE47, Q9UE48, Q9UFQ6	Gene names	SNRP70, RPU1, U1AP1
Domain Architecture
Description	U1 small nuclear ribonucleoprotein 70 kDa (U1 snRNP 70 kDa) (snRNP70) (U1-70K).

RU17_MOUSE
θ value	6.88961 (rank : 110)	NC score	0.003017 (rank : 113)
Query Neighborhood Hits	123	Target Neighborhood Hits	278	Shared Neighborhood Hits	4
SwissProt Accessions	Q62376, Q3UIW4	Gene names	Snrp70
Domain Architecture	No domain graphic available
Description	U1 small nuclear ribonucleoprotein 70 kDa (U1 SNRNP 70 kDa) (snRNP70).

SF01_MOUSE
θ value	6.88961 (rank : 111)	NC score	0.007650 (rank : 97)
Query Neighborhood Hits	123	Target Neighborhood Hits	240	Shared Neighborhood Hits	5
SwissProt Accessions	Q64213, O08817, P70167, Q61454, Q921Z4	Gene names	Sf1, Zfm1, Zfp162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (mZFM) (Zinc finger gene in MEN1 locus) (Mammalian branch point- binding protein mBBP) (BBP) (CW17).

SRRM1_MOUSE
θ value	6.88961 (rank : 112)	NC score	0.012062 (rank : 88)
Query Neighborhood Hits	123	Target Neighborhood Hits	966	Shared Neighborhood Hits	19
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

TBCD5_HUMAN
θ value	6.88961 (rank : 113)	NC score	0.005420 (rank : 106)
Query Neighborhood Hits	123	Target Neighborhood Hits	70	Shared Neighborhood Hits	2
SwissProt Accessions	Q92609	Gene names	TBC1D5, KIAA0210
Domain Architecture
Description	TBC1 domain family member 5.

TNNT2_HUMAN
θ value	6.88961 (rank : 114)	NC score	0.004604 (rank : 108)
Query Neighborhood Hits	123	Target Neighborhood Hits	433	Shared Neighborhood Hits	7
SwissProt Accessions	P45379, O60214, Q99596, Q99597, Q9UM96	Gene names	TNNT2
Domain Architecture	No domain graphic available
Description	Troponin T, cardiac muscle (TnTc) (Cardiac muscle troponin T) (cTnT).

TNNT2_MOUSE
θ value	6.88961 (rank : 115)	NC score	0.003681 (rank : 110)
Query Neighborhood Hits	123	Target Neighborhood Hits	395	Shared Neighborhood Hits	7
SwissProt Accessions	P50752, Q64360, Q64377	Gene names	Tnnt2
Domain Architecture	No domain graphic available
Description	Troponin T, cardiac muscle (TnTc) (Cardiac muscle troponin T) (cTnT).

DEK_MOUSE
θ value	8.99809 (rank : 116)	NC score	0.005488 (rank : 105)
Query Neighborhood Hits	123	Target Neighborhood Hits	280	Shared Neighborhood Hits	6
SwissProt Accessions	Q7TNV0, Q80VC5, Q8BZV6	Gene names	Dek
Domain Architecture	No domain graphic available
Description	Protein DEK.

DMD_HUMAN
θ value	8.99809 (rank : 117)	NC score	-0.000489 (rank : 119)
Query Neighborhood Hits	123	Target Neighborhood Hits	1135	Shared Neighborhood Hits	17
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

KAD6_HUMAN
θ value	8.99809 (rank : 118)	NC score	0.107701 (rank : 65)
Query Neighborhood Hits	123	Target Neighborhood Hits	46	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y3D8	Gene names	AK6
Domain Architecture
Description	Adenylate kinase isoenzyme 6 (EC 2.7.4.3) (ATP-AMP transphosphorylase 6).

PP14D_HUMAN
θ value	8.99809 (rank : 119)	NC score	0.006242 (rank : 102)
Query Neighborhood Hits	123	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NXH3	Gene names	PPP1R14D, GBPI
Domain Architecture	No domain graphic available
Description	Protein phosphatase 1 regulatory subunit 14D (Gastrointestinal and brain-specific PP1-inhibitory protein 1) (GBPI-1).

RUVB2_HUMAN
θ value	8.99809 (rank : 120)	NC score	0.123910 (rank : 60)
Query Neighborhood Hits	123	Target Neighborhood Hits	43	Shared Neighborhood Hits	38
SwissProt Accessions	Q9Y230, Q6PK27, Q9Y361	Gene names	RUVBL2, TIP48, TIP49B
Domain Architecture
Description	RuvB-like 2 (EC 3.6.1.-) (48 kDa TATA box-binding protein-interacting protein) (48 kDa TBP-interacting protein) (TIP49b) (Repressing pontin 52) (Reptin 52) (51 kDa erythrocyte cytosolic protein) (ECP-51) (TIP60-associated protein 54-beta) (TAP54-beta).

RUVB2_MOUSE
θ value	8.99809 (rank : 121)	NC score	0.120386 (rank : 61)
Query Neighborhood Hits	123	Target Neighborhood Hits	42	Shared Neighborhood Hits	37
SwissProt Accessions	Q9WTM5	Gene names	Ruvbl2
Domain Architecture
Description	RuvB-like 2 (EC 3.6.1.-) (p47 protein).

SAHH3_MOUSE
θ value	8.99809 (rank : 122)	NC score	0.008963 (rank : 95)
Query Neighborhood Hits	123	Target Neighborhood Hits	35	Shared Neighborhood Hits	4
SwissProt Accessions	Q68FL4, Q8BIH1	Gene names
Domain Architecture	No domain graphic available
Description	Putative adenosylhomocysteinase 3 (EC 3.3.1.1) (S-adenosyl-L- homocysteine hydrolase 3) (AdoHcyase 3).

SPTA3_HUMAN
θ value	8.99809 (rank : 123)	NC score	0.009503 (rank : 92)
Query Neighborhood Hits	123	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NHX4, Q86WX5, Q8N9Y6	Gene names	SPATA3, TSARG1
Domain Architecture	No domain graphic available
Description	Spermatogenesis-associated protein 3 (Testis spermatocyte apoptosis- related protein 1) (Testis and spermatogenesis cell-related protein 1).

KAD6_MOUSE
θ value	θ > 10 (rank : 124)	NC score	0.082420 (rank : 67)
Query Neighborhood Hits	123	Target Neighborhood Hits	34	Shared Neighborhood Hits	21
SwissProt Accessions	Q8VCP8	Gene names	Ak6
Domain Architecture	No domain graphic available
Description	Adenylate kinase isoenzyme 6 (EC 2.7.4.3) (ATP-AMP transphosphorylase 6).

RFC5_HUMAN
θ value	θ > 10 (rank : 125)	NC score	0.060017 (rank : 69)
Query Neighborhood Hits	123	Target Neighborhood Hits	60	Shared Neighborhood Hits	31
SwissProt Accessions	P40937	Gene names	RFC5
Domain Architecture
Description	Replication factor C subunit 5 (Replication factor C 36 kDa subunit) (RF-C 36 kDa subunit) (RFC36) (Activator 1 36 kDa subunit) (A1 36 kDa subunit).

RFC5_MOUSE
θ value	θ > 10 (rank : 126)	NC score	0.059264 (rank : 70)
Query Neighborhood Hits	123	Target Neighborhood Hits	58	Shared Neighborhood Hits	34
SwissProt Accessions	Q9D0F6	Gene names	Rfc5
Domain Architecture
Description	Replication factor C subunit 5 (Replication factor C 36 kDa subunit) (RF-C 36 kDa subunit) (RFC36) (Activator 1 36 kDa subunit) (A1 36 kDa subunit).

Hits sorted by NC score

KTNA1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	123	Target Neighborhood Hits	123	Shared Neighborhood Hits	123
SwissProt Accessions	Q9WV86	Gene names	Katna1
Domain Architecture	No domain graphic available
Description	Katanin p60 ATPase-containing subunit A1 (EC 3.6.4.3) (Katanin p60 subunit A1) (p60 katanin) (Lipotransin).

KTNA1_HUMAN
NC score	0.997142 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	123	Target Neighborhood Hits	117	Shared Neighborhood Hits	87
SwissProt Accessions	O75449, Q5TFA8, Q5TFA9, Q86VN2, Q9NU52	Gene names	KATNA1
Domain Architecture	No domain graphic available
Description	Katanin p60 ATPase-containing subunit A1 (EC 3.6.4.3) (Katanin p60 subunit A1) (p60 katanin).

KATL1_MOUSE
NC score	0.994086 (rank : 3)	θ value	1.31915e-176 (rank : 4)
Query Neighborhood Hits	123	Target Neighborhood Hits	77	Shared Neighborhood Hits	67
SwissProt Accessions	Q8K0T4	Gene names	Katnal1
Domain Architecture	No domain graphic available
Description	Katanin p60 ATPase-containing subunit A-like 1 (EC 3.6.4.3) (Katanin p60 subunit A-like 1) (p60 katanin-like 1).

KATL1_HUMAN
NC score	0.993928 (rank : 4)	θ value	1.19313e-177 (rank : 3)
Query Neighborhood Hits	123	Target Neighborhood Hits	80	Shared Neighborhood Hits	67
SwissProt Accessions	Q9BW62	Gene names	KATNAL1
Domain Architecture	No domain graphic available
Description	Katanin p60 ATPase-containing subunit A-like 1 (EC 3.6.4.3) (Katanin p60 subunit A-like 1) (p60 katanin-like 1).

SPAST_HUMAN
NC score	0.961189 (rank : 5)	θ value	6.32992e-62 (rank : 7)
Query Neighborhood Hits	123	Target Neighborhood Hits	100	Shared Neighborhood Hits	63
SwissProt Accessions	Q9UBP0, Q9UPR9	Gene names	SPAST, KIAA1083, SPG4
Domain Architecture
Description	Spastin.

SPAST_MOUSE
NC score	0.959766 (rank : 6)	θ value	6.32992e-62 (rank : 8)
Query Neighborhood Hits	123	Target Neighborhood Hits	138	Shared Neighborhood Hits	67
SwissProt Accessions	Q9QYY8, Q6ZPY6, Q80VE0, Q9CVK0	Gene names	Spast, Kiaa1083, Spg4
Domain Architecture	No domain graphic available
Description	Spastin.

ATAD1_HUMAN
NC score	0.959189 (rank : 7)	θ value	9.81109e-47 (rank : 11)
Query Neighborhood Hits	123	Target Neighborhood Hits	75	Shared Neighborhood Hits	62
SwissProt Accessions	Q8NBU5, Q6P4B9, Q8N3G1, Q8WYR9, Q969Y3	Gene names	ATAD1
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 1.

ATAD1_MOUSE
NC score	0.959189 (rank : 8)	θ value	9.81109e-47 (rank : 12)
Query Neighborhood Hits	123	Target Neighborhood Hits	75	Shared Neighborhood Hits	62
SwissProt Accessions	Q9D5T0, Q3U8V2, Q9D7A4	Gene names	Atad1
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 1.

VPS4B_HUMAN
NC score	0.958455 (rank : 9)	θ value	4.10295e-61 (rank : 10)
Query Neighborhood Hits	123	Target Neighborhood Hits	87	Shared Neighborhood Hits	63
SwissProt Accessions	O75351, Q9GZS7	Gene names	VPS4B, SKD1, VPS42
Domain Architecture
Description	Vacuolar protein sorting-associating protein 4B (Protein SKD1).

VPS4B_MOUSE
NC score	0.957988 (rank : 10)	θ value	1.41016e-61 (rank : 9)
Query Neighborhood Hits	123	Target Neighborhood Hits	86	Shared Neighborhood Hits	62
SwissProt Accessions	P46467, Q91W22, Q9R1C9	Gene names	Vps4b, Skd1
Domain Architecture
Description	Vacuolar protein sorting-associating protein 4B (Protein SKD1).

VPS4A_HUMAN
NC score	0.956185 (rank : 11)	θ value	2.56992e-63 (rank : 5)
Query Neighborhood Hits	123	Target Neighborhood Hits	95	Shared Neighborhood Hits	63
SwissProt Accessions	Q9UN37, Q8TF07, Q9UI03, Q9Y582	Gene names	VPS4A, VPS4
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associating protein 4A (SKD2 protein) (hVPS4) (VPS4-1).

VPS4A_MOUSE
NC score	0.956155 (rank : 12)	θ value	2.56992e-63 (rank : 6)
Query Neighborhood Hits	123	Target Neighborhood Hits	94	Shared Neighborhood Hits	63
SwissProt Accessions	Q8VEJ9, Q3TXT2	Gene names	Vps4a
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associating protein 4A.

TERA_HUMAN
NC score	0.927489 (rank : 13)	θ value	6.58091e-43 (rank : 15)
Query Neighborhood Hits	123	Target Neighborhood Hits	76	Shared Neighborhood Hits	65
SwissProt Accessions	P55072, Q969G7	Gene names	VCP
Domain Architecture
Description	Transitional endoplasmic reticulum ATPase (TER ATPase) (15S Mg(2+)- ATPase p97 subunit) (Valosin-containing protein) (VCP).

TERA_MOUSE
NC score	0.927447 (rank : 14)	θ value	6.58091e-43 (rank : 16)
Query Neighborhood Hits	123	Target Neighborhood Hits	76	Shared Neighborhood Hits	65
SwissProt Accessions	Q01853	Gene names	Vcp
Domain Architecture
Description	Transitional endoplasmic reticulum ATPase (TER ATPase) (15S Mg(2+)- ATPase p97 subunit) (Valosin-containing protein) (VCP).

PRS10_HUMAN
NC score	0.926819 (rank : 15)	θ value	1.51715e-39 (rank : 19)
Query Neighborhood Hits	123	Target Neighborhood Hits	95	Shared Neighborhood Hits	65
SwissProt Accessions	P62333, P49719, Q6IBU3, Q92524	Gene names	PSMC6, SUG2
Domain Architecture
Description	26S protease regulatory subunit S10B (Proteasome subunit p42) (Proteasome 26S subunit ATPase 6).

PRS10_MOUSE
NC score	0.926819 (rank : 16)	θ value	1.51715e-39 (rank : 20)
Query Neighborhood Hits	123	Target Neighborhood Hits	95	Shared Neighborhood Hits	65
SwissProt Accessions	P62334, P49719, Q3TKK1, Q810A6, Q92524, Q9CXH9	Gene names	Psmc6, Sug2
Domain Architecture
Description	26S protease regulatory subunit S10B (Proteasome subunit p42) (Proteasome 26S subunit ATPase 6).

FIGN_MOUSE
NC score	0.926348 (rank : 17)	θ value	3.72821e-46 (rank : 13)
Query Neighborhood Hits	123	Target Neighborhood Hits	165	Shared Neighborhood Hits	56
SwissProt Accessions	Q9ERZ6, Q3TPB0, Q3UP57, Q6PCM0	Gene names	Fign
Domain Architecture	No domain graphic available
Description	Fidgetin.

PRS8_HUMAN
NC score	0.925077 (rank : 18)	θ value	2.76489e-41 (rank : 17)
Query Neighborhood Hits	123	Target Neighborhood Hits	117	Shared Neighborhood Hits	63
SwissProt Accessions	P62195, O35051, O43208, P47210, P52915, P52916	Gene names	PSMC5, SUG1
Domain Architecture
Description	26S protease regulatory subunit 8 (Proteasome 26S subunit ATPase 5) (Proteasome subunit p45) (p45/SUG) (Thyroid hormone receptor- interacting protein 1) (TRIP1).

PRS8_MOUSE
NC score	0.925077 (rank : 19)	θ value	2.76489e-41 (rank : 18)
Query Neighborhood Hits	123	Target Neighborhood Hits	117	Shared Neighborhood Hits	63
SwissProt Accessions	P62196, O35051, P47210, P52915, P52916, Q3UL51, Q9CWN5	Gene names	Psmc5, Sug1
Domain Architecture
Description	26S protease regulatory subunit 8 (Proteasome 26S subunit ATPase 5) (Proteasome subunit p45) (p45/SUG) (mSUG1).

PRS6A_MOUSE
NC score	0.922854 (rank : 20)	θ value	8.32485e-38 (rank : 26)
Query Neighborhood Hits	123	Target Neighborhood Hits	85	Shared Neighborhood Hits	59
SwissProt Accessions	O88685	Gene names	Psmc3, Tbp1
Domain Architecture
Description	26S protease regulatory subunit 6A (Proteasome 26S subunit ATPase 3) (TAT-binding protein 1) (TBP-1).

PRS6A_HUMAN
NC score	0.922671 (rank : 21)	θ value	8.32485e-38 (rank : 25)
Query Neighborhood Hits	123	Target Neighborhood Hits	87	Shared Neighborhood Hits	59
SwissProt Accessions	P17980, Q96HD3	Gene names	PSMC3, TBP1
Domain Architecture
Description	26S protease regulatory subunit 6A (Proteasome 26S subunit ATPase 3) (TAT-binding protein 1) (TBP-1) (Proteasome subunit P50).

FIGN_HUMAN
NC score	0.921935 (rank : 22)	θ value	1.85029e-45 (rank : 14)
Query Neighborhood Hits	123	Target Neighborhood Hits	176	Shared Neighborhood Hits	56
SwissProt Accessions	Q5HY92, Q9H6M5, Q9NVZ9	Gene names	FIGN
Domain Architecture	No domain graphic available
Description	Fidgetin.

PRS4_HUMAN
NC score	0.921292 (rank : 23)	θ value	1.98146e-39 (rank : 21)
Query Neighborhood Hits	123	Target Neighborhood Hits	84	Shared Neighborhood Hits	64
SwissProt Accessions	P62191, P49014, Q03527, Q6IAW0, Q96AZ3	Gene names	PSMC1
Domain Architecture
Description	26S protease regulatory subunit 4 (P26s4) (Proteasome 26S subunit ATPase 1).

PRS4_MOUSE
NC score	0.921292 (rank : 24)	θ value	1.98146e-39 (rank : 22)
Query Neighborhood Hits	123	Target Neighborhood Hits	84	Shared Neighborhood Hits	64
SwissProt Accessions	P62192, P49014, Q03527, Q96AZ3	Gene names	Psmc1
Domain Architecture
Description	26S protease regulatory subunit 4 (P26s4) (Proteasome 26S subunit ATPase 1).

PEX1_HUMAN
NC score	0.919690 (rank : 25)	θ value	2.12192e-33 (rank : 29)
Query Neighborhood Hits	123	Target Neighborhood Hits	98	Shared Neighborhood Hits	62
SwissProt Accessions	O43933, Q96S71, Q96S72, Q96S73, Q99994	Gene names	PEX1
Domain Architecture
Description	Peroxisome biogenesis factor 1 (Peroxin-1) (Peroxisome biogenesis disorder protein 1).

NVL_MOUSE
NC score	0.917785 (rank : 26)	θ value	3.37985e-39 (rank : 23)
Query Neighborhood Hits	123	Target Neighborhood Hits	110	Shared Neighborhood Hits	66
SwissProt Accessions	Q9DBY8, Q3USC4, Q8BW27, Q8K2B5	Gene names	Nvl
Domain Architecture
Description	Nuclear valosin-containing protein-like (Nuclear VCP-like protein) (NVLp).

NVL_HUMAN
NC score	0.917151 (rank : 27)	θ value	7.52953e-39 (rank : 24)
Query Neighborhood Hits	123	Target Neighborhood Hits	112	Shared Neighborhood Hits	66
SwissProt Accessions	O15381, Q96EM7	Gene names	NVL
Domain Architecture
Description	Nuclear valosin-containing protein-like (Nuclear VCP-like protein) (NVLp).

PRS7_HUMAN
NC score	0.916733 (rank : 28)	θ value	4.00176e-32 (rank : 32)
Query Neighborhood Hits	123	Target Neighborhood Hits	66	Shared Neighborhood Hits	61
SwissProt Accessions	P35998	Gene names	PSMC2, MSS1
Domain Architecture
Description	26S protease regulatory subunit 7 (Proteasome 26S subunit ATPase 2) (Protein MSS1).

PRS7_MOUSE
NC score	0.916724 (rank : 29)	θ value	4.00176e-32 (rank : 33)
Query Neighborhood Hits	123	Target Neighborhood Hits	67	Shared Neighborhood Hits	61
SwissProt Accessions	P46471, O08531, Q3TGX5, Q9DBA1	Gene names	Psmc2, Mss1
Domain Architecture
Description	26S protease regulatory subunit 7 (Proteasome 26S subunit ATPase 2) (Protein MSS1).

PRS6B_HUMAN
NC score	0.915946 (rank : 30)	θ value	1.16434e-31 (rank : 35)
Query Neighborhood Hits	123	Target Neighborhood Hits	85	Shared Neighborhood Hits	57
SwissProt Accessions	P43686, Q96FV5, Q9UBM3, Q9UEX3	Gene names	PSMC4, TBP7
Domain Architecture
Description	26S protease regulatory subunit 6B (Proteasome 26S subunit ATPase 4) (MIP224) (MB67-interacting protein) (TAT-binding protein 7) (TBP-7).

PRS6B_MOUSE
NC score	0.914773 (rank : 31)	θ value	5.77852e-31 (rank : 37)
Query Neighborhood Hits	123	Target Neighborhood Hits	89	Shared Neighborhood Hits	57
SwissProt Accessions	P54775	Gene names	Psmc4, Tbp7
Domain Architecture
Description	26S protease regulatory subunit 6B (Proteasome 26S subunit ATPase 4) (MIP224) (MB67-interacting protein) (TAT-binding protein 7) (TBP-7) (CIP21).

PEX6_HUMAN
NC score	0.913518 (rank : 32)	θ value	2.67802e-36 (rank : 28)
Query Neighborhood Hits	123	Target Neighborhood Hits	99	Shared Neighborhood Hits	65
SwissProt Accessions	Q13608, Q8WYQ2, Q99476	Gene names	PEX6, PXAAA1
Domain Architecture
Description	Peroxisome assembly factor 2 (PAF-2) (Peroxisomal-type ATPase 1) (Peroxin-6) (Peroxisomal biogenesis factor 6).

PEX6_MOUSE
NC score	0.913375 (rank : 33)	θ value	5.39604e-37 (rank : 27)
Query Neighborhood Hits	123	Target Neighborhood Hits	94	Shared Neighborhood Hits	64
SwissProt Accessions	Q99LC9, Q6YNQ9	Gene names	Pex6
Domain Architecture	No domain graphic available
Description	Peroxisome assembly factor 2 (PAF-2) (Peroxisomal-type ATPase 1) (Peroxin-6) (Peroxisomal biogenesis factor 6).

YMEL1_MOUSE
NC score	0.901291 (rank : 34)	θ value	2.12192e-33 (rank : 30)
Query Neighborhood Hits	123	Target Neighborhood Hits	76	Shared Neighborhood Hits	60
SwissProt Accessions	O88967, Q7TNN5	Gene names	Yme1l1
Domain Architecture
Description	ATP-dependent metalloprotease YME1L1 (EC 3.4.24.-) (YME1-like protein 1) (ATP-dependent metalloprotease FtsH1).

YMEL1_HUMAN
NC score	0.897769 (rank : 35)	θ value	1.4233e-29 (rank : 40)
Query Neighborhood Hits	123	Target Neighborhood Hits	73	Shared Neighborhood Hits	60
SwissProt Accessions	Q96TA2, Q9H1Q0, Q9UMR9	Gene names	YME1L1, FTSH1, YME1L
Domain Architecture
Description	ATP-dependent metalloprotease YME1L1 (EC 3.4.24.-) (YME1-like protein 1) (ATP-dependent metalloprotease FtsH1) (Meg-4) (Presenilin- associated metalloprotease) (PAMP).

AFG31_MOUSE
NC score	0.896499 (rank : 36)	θ value	1.37539e-32 (rank : 31)
Query Neighborhood Hits	123	Target Neighborhood Hits	74	Shared Neighborhood Hits	62
SwissProt Accessions	Q920A7	Gene names	Afg3l1
Domain Architecture
Description	AFG3-like protein 1 (EC 3.4.24.-).

SPG7_HUMAN
NC score	0.896205 (rank : 37)	θ value	3.17079e-29 (rank : 41)
Query Neighborhood Hits	123	Target Neighborhood Hits	71	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UQ90, O75756, Q96IB0	Gene names	SPG7, CAR, CMAR, PGN
Domain Architecture
Description	Paraplegin (EC 3.4.24.-) (Spastic paraplegia protein 7).

AFG32_HUMAN
NC score	0.890656 (rank : 38)	θ value	2.19584e-30 (rank : 38)
Query Neighborhood Hits	123	Target Neighborhood Hits	72	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Y4W6	Gene names	AFG3L2
Domain Architecture
Description	AFG3-like protein 2 (EC 3.4.24.-) (Paraplegin-like protein).

AFG32_MOUSE
NC score	0.890492 (rank : 39)	θ value	2.86786e-30 (rank : 39)
Query Neighborhood Hits	123	Target Neighborhood Hits	73	Shared Neighborhood Hits	62
SwissProt Accessions	Q8JZQ2	Gene names	Afg3l2
Domain Architecture	No domain graphic available
Description	AFG3-like protein 2 (EC 3.4.24.-).

NSF_HUMAN
NC score	0.876233 (rank : 40)	θ value	3.75424e-22 (rank : 42)
Query Neighborhood Hits	123	Target Neighborhood Hits	74	Shared Neighborhood Hits	64
SwissProt Accessions	P46459, Q9UKZ2	Gene names	NSF
Domain Architecture
Description	Vesicle-fusing ATPase (EC 3.6.4.6) (Vesicular-fusion protein NSF) (N- ethylmaleimide sensitive fusion protein) (NEM-sensitive fusion protein).

NSF_MOUSE
NC score	0.875738 (rank : 41)	θ value	3.75424e-22 (rank : 43)
Query Neighborhood Hits	123	Target Neighborhood Hits	73	Shared Neighborhood Hits	61
SwissProt Accessions	P46460	Gene names	Nsf, Skd2
Domain Architecture
Description	Vesicle-fusing ATPase (EC 3.6.4.6) (Vesicular-fusion protein NSF) (N- ethylmaleimide sensitive fusion protein) (NEM-sensitive fusion protein) (SKD2 protein).

ATAD2_MOUSE
NC score	0.868947 (rank : 42)	θ value	1.98606e-31 (rank : 36)
Query Neighborhood Hits	123	Target Neighborhood Hits	167	Shared Neighborhood Hits	62
SwissProt Accessions	Q8CDM1	Gene names	Atad2
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 2.

ATAD2_HUMAN
NC score	0.851530 (rank : 43)	θ value	8.91499e-32 (rank : 34)
Query Neighborhood Hits	123	Target Neighborhood Hits	322	Shared Neighborhood Hits	64
SwissProt Accessions	Q6PL18, Q658P2, Q68CQ0, Q6PJV6, Q8N890, Q9UHS5	Gene names	ATAD2
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 2.

TRP13_MOUSE
NC score	0.713959 (rank : 44)	θ value	1.80886e-08 (rank : 47)
Query Neighborhood Hits	123	Target Neighborhood Hits	81	Shared Neighborhood Hits	58
SwissProt Accessions	Q3UA06, Q3UQG6, Q9CWW8	Gene names	Trip13
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 13 (Thyroid hormone receptor interactor 13) (Trip-13).

TRP13_HUMAN
NC score	0.712445 (rank : 45)	θ value	3.08544e-08 (rank : 48)
Query Neighborhood Hits	123	Target Neighborhood Hits	81	Shared Neighborhood Hits	59
SwissProt Accessions	Q15645, O15324	Gene names	TRIP13
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 13 (Thyroid hormone receptor interactor 13) (Trip-13) (Human papillomavirus type 16 E1 protein- binding protein) (HPV16 E1 protein-binding protein) (16E1-BP).

ATD3A_HUMAN
NC score	0.638257 (rank : 46)	θ value	1.80886e-08 (rank : 46)
Query Neighborhood Hits	123	Target Neighborhood Hits	248	Shared Neighborhood Hits	64
SwissProt Accessions	Q9NVI7, Q8N275, Q96A50	Gene names	ATAD3A
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 3A.

ATD3B_HUMAN
NC score	0.622660 (rank : 47)	θ value	2.79066e-09 (rank : 44)
Query Neighborhood Hits	123	Target Neighborhood Hits	340	Shared Neighborhood Hits	60
SwissProt Accessions	Q5T9A4, Q6ZRB5, Q9BUK4, Q9ULE7	Gene names	ATAD3B, KIAA1273
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 3B.

ATAD3_MOUSE
NC score	0.614020 (rank : 48)	θ value	1.80886e-08 (rank : 45)
Query Neighborhood Hits	123	Target Neighborhood Hits	326	Shared Neighborhood Hits	63
SwissProt Accessions	Q925I1, Q3UE74, Q69ZM7, Q8C6C6	Gene names	Atad3, Atad3a, Kiaa1273
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 3 (AAA-ATPase TOB3).

BCS1_HUMAN
NC score	0.570372 (rank : 49)	θ value	4.03905 (rank : 89)
Query Neighborhood Hits	123	Target Neighborhood Hits	61	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Y276, Q7Z2V7	Gene names	BCS1L, BCS1
Domain Architecture
Description	Mitochondrial chaperone BCS1 (BCS1-like protein) (H-BCS1).

BCS1_MOUSE
NC score	0.559813 (rank : 50)	θ value	6.88961 (rank : 102)
Query Neighborhood Hits	123	Target Neighborhood Hits	64	Shared Neighborhood Hits	52
SwissProt Accessions	Q9CZP5	Gene names	Bcs1l
Domain Architecture
Description	Mitochondrial chaperone BCS1 (BCS1-like protein).

CLPX_HUMAN
NC score	0.425665 (rank : 51)	θ value	0.00509761 (rank : 49)
Query Neighborhood Hits	123	Target Neighborhood Hits	72	Shared Neighborhood Hits	51
SwissProt Accessions	O76031, Q9H4D9	Gene names	CLPX
Domain Architecture
Description	ATP-dependent Clp protease ATP-binding subunit ClpX-like, mitochondrial precursor.

CLPX_MOUSE
NC score	0.422852 (rank : 52)	θ value	0.00509761 (rank : 50)
Query Neighborhood Hits	123	Target Neighborhood Hits	73	Shared Neighborhood Hits	51
SwissProt Accessions	Q9JHS4, Q9WVD1	Gene names	Clpx
Domain Architecture
Description	ATP-dependent Clp protease ATP-binding subunit ClpX-like, mitochondrial precursor.

LONM_HUMAN
NC score	0.413642 (rank : 53)	θ value	0.125558 (rank : 56)
Query Neighborhood Hits	123	Target Neighborhood Hits	130	Shared Neighborhood Hits	58
SwissProt Accessions	P36776, P36777, Q9UQ95	Gene names	PRSS15
Domain Architecture
Description	Lon protease homolog, mitochondrial precursor (EC 3.4.21.-) (Lon protease-like protein) (LONP) (LONHs).

RUVB1_HUMAN
NC score	0.324473 (rank : 54)	θ value	0.0563607 (rank : 53)
Query Neighborhood Hits	123	Target Neighborhood Hits	78	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Y265, Q9BSX9	Gene names	RUVBL1, NMP238, TIP49, TIP49A
Domain Architecture
Description	RuvB-like 1 (EC 3.6.1.-) (49 kDa TATA box-binding protein-interacting protein) (49 kDa TBP-interacting protein) (TIP49a) (Pontin 52) (Nuclear matrix protein 238) (NMP 238) (54 kDa erythrocyte cytosolic protein) (ECP-54) (TIP60-associated protein 54-alpha) (TAP54-alpha).

RUVB1_MOUSE
NC score	0.324434 (rank : 55)	θ value	0.0563607 (rank : 54)
Query Neighborhood Hits	123	Target Neighborhood Hits	78	Shared Neighborhood Hits	59
SwissProt Accessions	P60122, O35753	Gene names	Ruvbl1, Tip49, Tip49a
Domain Architecture
Description	RuvB-like 1 (EC 3.6.1.-) (49 kDa TATA box-binding protein-interacting protein) (49 kDa TBP-interacting protein) (TIP49a) (Pontin 52) (DNA helicase p50).

WRIP1_HUMAN
NC score	0.230738 (rank : 56)	θ value	0.47712 (rank : 63)
Query Neighborhood Hits	123	Target Neighborhood Hits	100	Shared Neighborhood Hits	51
SwissProt Accessions	Q96S55, Q53EP6, Q59ET8, Q5W0E2, Q5W0E4, Q8WV26, Q9H681, Q9NRJ6	Gene names	WRNIP1, WHIP
Domain Architecture	No domain graphic available
Description	ATPase WRNIP1 (Werner helicase-interacting protein 1).

WRIP1_MOUSE
NC score	0.229241 (rank : 57)	θ value	0.62314 (rank : 67)
Query Neighborhood Hits	123	Target Neighborhood Hits	93	Shared Neighborhood Hits	52
SwissProt Accessions	Q91XU0, Q3TCT7, Q6PDF0, Q8BUW5, Q8BWP6, Q8BY55, Q921W3, Q9EQL3	Gene names	Wrnip1, Whip
Domain Architecture	No domain graphic available
Description	ATPase WRNIP1 (Werner helicase-interacting protein 1).

THNSL_MOUSE
NC score	0.131743 (rank : 58)	θ value	0.62314 (rank : 66)
Query Neighborhood Hits	123	Target Neighborhood Hits	47	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BH55	Gene names	Thnsl1
Domain Architecture	No domain graphic available
Description	Threonine synthase-like 1.

RFC1_MOUSE
NC score	0.131007 (rank : 59)	θ value	1.38821 (rank : 76)
Query Neighborhood Hits	123	Target Neighborhood Hits	290	Shared Neighborhood Hits	53
SwissProt Accessions	P35601	Gene names	Rfc1, Ibf-1, Recc1
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (A1-P145) (Differentiation- specific element-binding protein) (ISRE-binding protein).

RUVB2_HUMAN
NC score	0.123910 (rank : 60)	θ value	8.99809 (rank : 120)
Query Neighborhood Hits	123	Target Neighborhood Hits	43	Shared Neighborhood Hits	38
SwissProt Accessions	Q9Y230, Q6PK27, Q9Y361	Gene names	RUVBL2, TIP48, TIP49B
Domain Architecture
Description	RuvB-like 2 (EC 3.6.1.-) (48 kDa TATA box-binding protein-interacting protein) (48 kDa TBP-interacting protein) (TIP49b) (Repressing pontin 52) (Reptin 52) (51 kDa erythrocyte cytosolic protein) (ECP-51) (TIP60-associated protein 54-beta) (TAP54-beta).

RUVB2_MOUSE
NC score	0.120386 (rank : 61)	θ value	8.99809 (rank : 121)
Query Neighborhood Hits	123	Target Neighborhood Hits	42	Shared Neighborhood Hits	37
SwissProt Accessions	Q9WTM5	Gene names	Ruvbl2
Domain Architecture
Description	RuvB-like 2 (EC 3.6.1.-) (p47 protein).

RFC1_HUMAN
NC score	0.120103 (rank : 62)	θ value	1.38821 (rank : 75)
Query Neighborhood Hits	123	Target Neighborhood Hits	352	Shared Neighborhood Hits	51
SwissProt Accessions	P35251, Q5XKF5, Q6PKU0, Q86V41, Q86V46	Gene names	RFC1, RFC140
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (DNA-binding protein PO-GA).

THNSL_HUMAN
NC score	0.119957 (rank : 63)	θ value	2.36792 (rank : 82)
Query Neighborhood Hits	123	Target Neighborhood Hits	47	Shared Neighborhood Hits	36
SwissProt Accessions	Q8IYQ7, Q5VV21	Gene names	THNSL1
Domain Architecture	No domain graphic available
Description	Threonine synthase-like 1.

RFC4_HUMAN
NC score	0.108797 (rank : 64)	θ value	0.813845 (rank : 69)
Query Neighborhood Hits	123	Target Neighborhood Hits	64	Shared Neighborhood Hits	38
SwissProt Accessions	P35249, Q6FHX7	Gene names	RFC4
Domain Architecture
Description	Replication factor C subunit 4 (Replication factor C 37 kDa subunit) (RF-C 37 kDa subunit) (RFC37) (Activator 1 37 kDa subunit) (A1 37 kDa subunit).

KAD6_HUMAN
NC score	0.107701 (rank : 65)	θ value	8.99809 (rank : 118)
Query Neighborhood Hits	123	Target Neighborhood Hits	46	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y3D8	Gene names	AK6
Domain Architecture
Description	Adenylate kinase isoenzyme 6 (EC 2.7.4.3) (ATP-AMP transphosphorylase 6).

RFC4_MOUSE
NC score	0.097165 (rank : 66)	θ value	2.36792 (rank : 81)
Query Neighborhood Hits	123	Target Neighborhood Hits	65	Shared Neighborhood Hits	38
SwissProt Accessions	Q99J62	Gene names	Rfc4
Domain Architecture	No domain graphic available
Description	Replication factor C subunit 4.

KAD6_MOUSE
NC score	0.082420 (rank : 67)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	123	Target Neighborhood Hits	34	Shared Neighborhood Hits	21
SwissProt Accessions	Q8VCP8	Gene names	Ak6
Domain Architecture	No domain graphic available
Description	Adenylate kinase isoenzyme 6 (EC 2.7.4.3) (ATP-AMP transphosphorylase 6).

IMUP_HUMAN
NC score	0.071806 (rank : 68)	θ value	1.06291 (rank : 71)
Query Neighborhood Hits	123	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	Q9GZP8, Q96H58, Q9HCR4	Gene names	IMUP, C19orf33
Domain Architecture	No domain graphic available
Description	Immortalization-up-regulated protein (Hepatocyte growth factor activator inhibitor type 2-related small protein) (HAI-2-related small protein) (H2RSP).

RFC5_HUMAN
NC score	0.060017 (rank : 69)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	123	Target Neighborhood Hits	60	Shared Neighborhood Hits	31
SwissProt Accessions	P40937	Gene names	RFC5
Domain Architecture
Description	Replication factor C subunit 5 (Replication factor C 36 kDa subunit) (RF-C 36 kDa subunit) (RFC36) (Activator 1 36 kDa subunit) (A1 36 kDa subunit).

RFC5_MOUSE
NC score	0.059264 (rank : 70)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	123	Target Neighborhood Hits	58	Shared Neighborhood Hits	34
SwissProt Accessions	Q9D0F6	Gene names	Rfc5
Domain Architecture
Description	Replication factor C subunit 5 (Replication factor C 36 kDa subunit) (RF-C 36 kDa subunit) (RFC36) (Activator 1 36 kDa subunit) (A1 36 kDa subunit).

BANK1_MOUSE
NC score	0.038822 (rank : 71)	θ value	0.125558 (rank : 55)
Query Neighborhood Hits	123	Target Neighborhood Hits	63	Shared Neighborhood Hits	6
SwissProt Accessions	Q80VH0, Q3U178, Q8BRV6, Q8BRY8	Gene names	Bank1
Domain Architecture	No domain graphic available
Description	B-cell scaffold protein with ankyrin repeats (Protein AVIEF).

BANK1_HUMAN
NC score	0.032564 (rank : 72)	θ value	0.47712 (rank : 61)
Query Neighborhood Hits	123	Target Neighborhood Hits	44	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NDB2, Q8N5K8, Q8NB56, Q8WYN5, Q9NWP2	Gene names	BANK1
Domain Architecture	No domain graphic available
Description	B-cell scaffold protein with ankyrin repeats.

CIR_MOUSE
NC score	0.031967 (rank : 73)	θ value	0.21417 (rank : 57)
Query Neighborhood Hits	123	Target Neighborhood Hits	255	Shared Neighborhood Hits	10
SwissProt Accessions	Q9DA19, Q3V2N9, Q4KL44, Q52KL9, Q5FW66	Gene names	Cir
Domain Architecture	No domain graphic available
Description	CBF1-interacting corepressor.

SYYM_MOUSE
NC score	0.030369 (rank : 74)	θ value	0.21417 (rank : 58)
Query Neighborhood Hits	123	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BYL4, Q6PAH7	Gene names	Yars2
Domain Architecture	No domain graphic available
Description	Tyrosyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.1) (Tyrosine--tRNA ligase) (TyrRS).

LIMA1_MOUSE
NC score	0.025879 (rank : 75)	θ value	0.0113563 (rank : 51)
Query Neighborhood Hits	123	Target Neighborhood Hits	298	Shared Neighborhood Hits	8
SwissProt Accessions	Q9ERG0, Q9ERG1	Gene names	Lima1, D15Ertd366e, Eplin
Domain Architecture
Description	LIM domain and actin-binding protein 1 (Epithelial protein lost in neoplasm) (mEPLIN).

SYYM_HUMAN
NC score	0.023580 (rank : 76)	θ value	3.0926 (rank : 87)
Query Neighborhood Hits	123	Target Neighborhood Hits	5	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y2Z4, Q9H817	Gene names	YARS2
Domain Architecture	No domain graphic available
Description	Tyrosyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.1) (Tyrosine--tRNA ligase) (TyrRS).

THOC2_HUMAN
NC score	0.020650 (rank : 77)	θ value	1.81305 (rank : 78)
Query Neighborhood Hits	123	Target Neighborhood Hits	337	Shared Neighborhood Hits	11
SwissProt Accessions	Q8NI27, Q9H8I6	Gene names	THOC2, CXorf3
Domain Architecture	No domain graphic available
Description	THO complex subunit 2 (Tho2).

FOXM1_HUMAN
NC score	0.020471 (rank : 78)	θ value	0.0252991 (rank : 52)
Query Neighborhood Hits	123	Target Neighborhood Hits	167	Shared Neighborhood Hits	7
SwissProt Accessions	Q08050, O43258, O43259, O43260, Q4ZGG7, Q9BRL2	Gene names	FOXM1, FKHL16, HFH11, MPP2, WIN
Domain Architecture
Description	Forkhead box protein M1 (Forkhead-related protein FKHL16) (Hepatocyte nuclear factor 3 forkhead homolog 11) (HNF-3/fork-head homolog 11) (HFH-11) (Winged helix factor from INS-1 cells) (M-phase phosphoprotein 2) (MPM-2 reactive phosphoprotein 2) (Transcription factor Trident).

TM131_MOUSE
NC score	0.018468 (rank : 79)	θ value	1.06291 (rank : 73)
Query Neighborhood Hits	123	Target Neighborhood Hits	156	Shared Neighborhood Hits	5
SwissProt Accessions	O70472	Gene names	Tmem131, D1Bwg0491e, Rw1
Domain Architecture	No domain graphic available
Description	Transmembrane protein 131 (Protein RW1).

SMBP2_MOUSE
NC score	0.018451 (rank : 80)	θ value	3.0926 (rank : 85)
Query Neighborhood Hits	123	Target Neighborhood Hits	104	Shared Neighborhood Hits	7
SwissProt Accessions	P40694	Gene names	Ighmbp2, Smbp-2, Smbp2
Domain Architecture
Description	DNA-binding protein SMUBP-2 (EC 3.6.1.-) (ATP-dependent helicase IGHMBP2) (Immunoglobulin mu-binding protein 2) (SMUBP-2) (Cardiac transcription factor 1) (CATF1).

MAP4_HUMAN
NC score	0.016057 (rank : 81)	θ value	2.36792 (rank : 80)
Query Neighborhood Hits	123	Target Neighborhood Hits	428	Shared Neighborhood Hits	13
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

SRRM2_HUMAN
NC score	0.014807 (rank : 82)	θ value	0.62314 (rank : 65)
Query Neighborhood Hits	123	Target Neighborhood Hits	1296	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

RTKN_MOUSE
NC score	0.014788 (rank : 83)	θ value	4.03905 (rank : 90)
Query Neighborhood Hits	123	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C6B2, Q61192, Q8VIG7	Gene names	Rtkn
Domain Architecture	No domain graphic available
Description	Rhotekin.

SRRM2_MOUSE
NC score	0.014711 (rank : 84)	θ value	5.27518 (rank : 101)
Query Neighborhood Hits	123	Target Neighborhood Hits	1470	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

BRD4_MOUSE
NC score	0.014262 (rank : 85)	θ value	6.88961 (rank : 103)
Query Neighborhood Hits	123	Target Neighborhood Hits	845	Shared Neighborhood Hits	12
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

SFR12_HUMAN
NC score	0.013185 (rank : 86)	θ value	0.62314 (rank : 64)
Query Neighborhood Hits	123	Target Neighborhood Hits	553	Shared Neighborhood Hits	11
SwissProt Accessions	Q8WXA9, Q86X37	Gene names	SFRS12, SRRP86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86) (Splicing regulatory protein 508) (SRrp508).

SAHH3_HUMAN
NC score	0.012748 (rank : 87)	θ value	0.813845 (rank : 70)
Query Neighborhood Hits	123	Target Neighborhood Hits	23	Shared Neighborhood Hits	4
SwissProt Accessions	Q96HN2, O94917	Gene names	KIAA0828
Domain Architecture
Description	Putative adenosylhomocysteinase 3 (EC 3.3.1.1) (S-adenosyl-L- homocysteine hydrolase 3) (AdoHcyase 3).

SRRM1_MOUSE
NC score	0.012062 (rank : 88)	θ value	6.88961 (rank : 112)
Query Neighborhood Hits	123	Target Neighborhood Hits	966	Shared Neighborhood Hits	19
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

TAF3_HUMAN
NC score	0.011684 (rank : 89)	θ value	1.06291 (rank : 72)
Query Neighborhood Hits	123	Target Neighborhood Hits	568	Shared Neighborhood Hits	14
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

SRRM1_HUMAN
NC score	0.011612 (rank : 90)	θ value	4.03905 (rank : 91)
Query Neighborhood Hits	123	Target Neighborhood Hits	690	Shared Neighborhood Hits	15
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

APC_MOUSE
NC score	0.009745 (rank : 91)	θ value	2.36792 (rank : 79)
Query Neighborhood Hits	123	Target Neighborhood Hits	441	Shared Neighborhood Hits	7
SwissProt Accessions	Q61315, Q62044	Gene names	Apc
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC) (mAPC).

SPTA3_HUMAN
NC score	0.009503 (rank : 92)	θ value	8.99809 (rank : 123)
Query Neighborhood Hits	123	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NHX4, Q86WX5, Q8N9Y6	Gene names	SPATA3, TSARG1
Domain Architecture	No domain graphic available
Description	Spermatogenesis-associated protein 3 (Testis spermatocyte apoptosis- related protein 1) (Testis and spermatogenesis cell-related protein 1).

CAC1B_MOUSE
NC score	0.009474 (rank : 93)	θ value	0.47712 (rank : 62)
Query Neighborhood Hits	123	Target Neighborhood Hits	351	Shared Neighborhood Hits	7
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

DYH5_HUMAN
NC score	0.009203 (rank : 94)	θ value	5.27518 (rank : 97)
Query Neighborhood Hits	123	Target Neighborhood Hits	323	Shared Neighborhood Hits	10
SwissProt Accessions	Q8TE73, Q92860, Q96L74, Q9H5S7, Q9HCG9	Gene names	DNAH5, DNAHC5, KIAA1603
Domain Architecture	No domain graphic available
Description	Ciliary dynein heavy chain 5 (Axonemal beta dynein heavy chain 5) (HL1).

SAHH3_MOUSE
NC score	0.008963 (rank : 95)	θ value	8.99809 (rank : 122)
Query Neighborhood Hits	123	Target Neighborhood Hits	35	Shared Neighborhood Hits	4
SwissProt Accessions	Q68FL4, Q8BIH1	Gene names
Domain Architecture	No domain graphic available
Description	Putative adenosylhomocysteinase 3 (EC 3.3.1.1) (S-adenosyl-L- homocysteine hydrolase 3) (AdoHcyase 3).

CHD3_HUMAN
NC score	0.008704 (rank : 96)	θ value	0.365318 (rank : 59)
Query Neighborhood Hits	123	Target Neighborhood Hits	397	Shared Neighborhood Hits	8
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

SF01_MOUSE
NC score	0.007650 (rank : 97)	θ value	6.88961 (rank : 111)
Query Neighborhood Hits	123	Target Neighborhood Hits	240	Shared Neighborhood Hits	5
SwissProt Accessions	Q64213, O08817, P70167, Q61454, Q921Z4	Gene names	Sf1, Zfm1, Zfp162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (mZFM) (Zinc finger gene in MEN1 locus) (Mammalian branch point- binding protein mBBP) (BBP) (CW17).

FA44A_HUMAN
NC score	0.007605 (rank : 98)	θ value	5.27518 (rank : 98)
Query Neighborhood Hits	123	Target Neighborhood Hits	280	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NFC6, Q6P0M8	Gene names	FAM44A
Domain Architecture	No domain graphic available
Description	Protein FAM44A.

SF01_HUMAN
NC score	0.007575 (rank : 99)	θ value	5.27518 (rank : 100)
Query Neighborhood Hits	123	Target Neighborhood Hits	287	Shared Neighborhood Hits	5
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

AFF4_HUMAN
NC score	0.006995 (rank : 100)	θ value	4.03905 (rank : 88)
Query Neighborhood Hits	123	Target Neighborhood Hits	611	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

K0427_HUMAN
NC score	0.006312 (rank : 101)	θ value	6.88961 (rank : 106)
Query Neighborhood Hits	123	Target Neighborhood Hits	55	Shared Neighborhood Hits	3
SwissProt Accessions	O43310, Q8IVD5	Gene names	KIAA0427
Domain Architecture	No domain graphic available
Description	Protein KIAA0427.

PP14D_HUMAN
NC score	0.006242 (rank : 102)	θ value	8.99809 (rank : 119)
Query Neighborhood Hits	123	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NXH3	Gene names	PPP1R14D, GBPI
Domain Architecture	No domain graphic available
Description	Protein phosphatase 1 regulatory subunit 14D (Gastrointestinal and brain-specific PP1-inhibitory protein 1) (GBPI-1).

TSH1_MOUSE
NC score	0.006147 (rank : 103)	θ value	4.03905 (rank : 93)
Query Neighborhood Hits	123	Target Neighborhood Hits	675	Shared Neighborhood Hits	11
SwissProt Accessions	Q5DTH5, Q6PE60, Q8VD19, Q9JLD5	Gene names	Tshz1, Kiaa4206, Sdccag33, Tsh1
Domain Architecture	No domain graphic available
Description	Teashirt homolog 1 (Serologically defined colon cancer antigen 3 homolog).

AP3D1_HUMAN
NC score	0.005742 (rank : 104)	θ value	3.0926 (rank : 83)
Query Neighborhood Hits	123	Target Neighborhood Hits	254	Shared Neighborhood Hits	5
SwissProt Accessions	O14617, O00202, O75262, Q59HF5, Q96G11, Q9H3C6	Gene names	AP3D1
Domain Architecture
Description	AP-3 complex subunit delta-1 (Adapter-related protein complex 3 subunit delta-1) (Delta-adaptin 3) (AP-3 complex subunit delta) (Delta-adaptin).

DEK_MOUSE
NC score	0.005488 (rank : 105)	θ value	8.99809 (rank : 116)
Query Neighborhood Hits	123	Target Neighborhood Hits	280	Shared Neighborhood Hits	6
SwissProt Accessions	Q7TNV0, Q80VC5, Q8BZV6	Gene names	Dek
Domain Architecture	No domain graphic available
Description	Protein DEK.

TBCD5_HUMAN
NC score	0.005420 (rank : 106)	θ value	6.88961 (rank : 113)
Query Neighborhood Hits	123	Target Neighborhood Hits	70	Shared Neighborhood Hits	2
SwissProt Accessions	Q92609	Gene names	TBC1D5, KIAA0210
Domain Architecture
Description	TBC1 domain family member 5.

CBLB_MOUSE
NC score	0.004919 (rank : 107)	θ value	6.88961 (rank : 104)
Query Neighborhood Hits	123	Target Neighborhood Hits	277	Shared Neighborhood Hits	4
SwissProt Accessions	Q3TTA7	Gene names	Cblb
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b).

TNNT2_HUMAN
NC score	0.004604 (rank : 108)	θ value	6.88961 (rank : 114)
Query Neighborhood Hits	123	Target Neighborhood Hits	433	Shared Neighborhood Hits	7
SwissProt Accessions	P45379, O60214, Q99596, Q99597, Q9UM96	Gene names	TNNT2
Domain Architecture	No domain graphic available
Description	Troponin T, cardiac muscle (TnTc) (Cardiac muscle troponin T) (cTnT).

MAP1B_HUMAN
NC score	0.004005 (rank : 109)	θ value	5.27518 (rank : 99)
Query Neighborhood Hits	123	Target Neighborhood Hits	903	Shared Neighborhood Hits	19
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

TNNT2_MOUSE
NC score	0.003681 (rank : 110)	θ value	6.88961 (rank : 115)
Query Neighborhood Hits	123	Target Neighborhood Hits	395	Shared Neighborhood Hits	7
SwissProt Accessions	P50752, Q64360, Q64377	Gene names	Tnnt2
Domain Architecture	No domain graphic available
Description	Troponin T, cardiac muscle (TnTc) (Cardiac muscle troponin T) (cTnT).

TGM5_MOUSE
NC score	0.003603 (rank : 111)	θ value	4.03905 (rank : 92)
Query Neighborhood Hits	123	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D7I9, Q3V1F9	Gene names	Tgm5
Domain Architecture	No domain graphic available
Description	Protein-glutamine gamma-glutamyltransferase 5 (EC 2.3.2.13) (Transglutaminase-5) (TGase 5).

MAGI1_MOUSE
NC score	0.003376 (rank : 112)	θ value	1.81305 (rank : 77)
Query Neighborhood Hits	123	Target Neighborhood Hits	403	Shared Neighborhood Hits	11
SwissProt Accessions	Q6RHR9, O54893, O54894, O54895	Gene names	Magi1, Baiap1, Bap1
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1).

RU17_MOUSE
NC score	0.003017 (rank : 113)	θ value	6.88961 (rank : 110)
Query Neighborhood Hits	123	Target Neighborhood Hits	278	Shared Neighborhood Hits	4
SwissProt Accessions	Q62376, Q3UIW4	Gene names	Snrp70
Domain Architecture	No domain graphic available
Description	U1 small nuclear ribonucleoprotein 70 kDa (U1 SNRNP 70 kDa) (snRNP70).

RU17_HUMAN
NC score	0.002883 (rank : 114)	θ value	6.88961 (rank : 109)
Query Neighborhood Hits	123	Target Neighborhood Hits	280	Shared Neighborhood Hits	3
SwissProt Accessions	P08621, P78493, P78494, Q15364, Q15686, Q15687, Q15689, Q99377, Q9UE45, Q9UE46, Q9UE47, Q9UE48, Q9UFQ6	Gene names	SNRP70, RPU1, U1AP1
Domain Architecture
Description	U1 small nuclear ribonucleoprotein 70 kDa (U1 snRNP 70 kDa) (snRNP70) (U1-70K).

PO6F2_MOUSE
NC score	0.002327 (rank : 115)	θ value	1.38821 (rank : 74)
Query Neighborhood Hits	123	Target Neighborhood Hits	639	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BJI4	Gene names	Pou6f2
Domain Architecture	No domain graphic available
Description	POU domain, class 6, transcription factor 2.

CPXM2_HUMAN
NC score	0.002165 (rank : 116)	θ value	5.27518 (rank : 96)
Query Neighborhood Hits	123	Target Neighborhood Hits	84	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N436	Gene names	CPXM2
Domain Architecture
Description	Carboxypeptidase-like protein X2 precursor.

GIT1_HUMAN
NC score	0.000293 (rank : 117)	θ value	6.88961 (rank : 105)
Query Neighborhood Hits	123	Target Neighborhood Hits	336	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y2X7, Q86SS0, Q9BRJ4	Gene names	GIT1
Domain Architecture
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1) (Cool-associated and tyrosine-phosphorylated protein 1) (Cat-1).

BARX2_MOUSE
NC score	-0.000016 (rank : 118)	θ value	5.27518 (rank : 95)
Query Neighborhood Hits	123	Target Neighborhood Hits	335	Shared Neighborhood Hits	5
SwissProt Accessions	O08686	Gene names	Barx2
Domain Architecture
Description	Homeobox protein BarH-like 2.

DMD_HUMAN
NC score	-0.000489 (rank : 119)	θ value	8.99809 (rank : 117)
Query Neighborhood Hits	123	Target Neighborhood Hits	1135	Shared Neighborhood Hits	17
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

UTRO_HUMAN
NC score	-0.000556 (rank : 120)	θ value	4.03905 (rank : 94)
Query Neighborhood Hits	123	Target Neighborhood Hits	960	Shared Neighborhood Hits	8
SwissProt Accessions	P46939	Gene names	UTRN, DMDL
Domain Architecture
Description	Utrophin (Dystrophin-related protein 1) (DRP1) (DRP).

MYH10_HUMAN
NC score	-0.003399 (rank : 121)	θ value	6.88961 (rank : 107)
Query Neighborhood Hits	123	Target Neighborhood Hits	1620	Shared Neighborhood Hits	18
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

PRP4B_HUMAN
NC score	-0.004073 (rank : 122)	θ value	6.88961 (rank : 108)
Query Neighborhood Hits	123	Target Neighborhood Hits	1030	Shared Neighborhood Hits	13
SwissProt Accessions	Q13523, Q8TDP2, Q96QT7, Q9UEE6	Gene names	PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (PRP4 kinase).

TITIN_HUMAN
NC score	-0.004121 (rank : 123)	θ value	0.365318 (rank : 60)
Query Neighborhood Hits	123	Target Neighborhood Hits	2923	Shared Neighborhood Hits	25
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

CTCF_HUMAN
NC score	-0.004244 (rank : 124)	θ value	0.813845 (rank : 68)
Query Neighborhood Hits	123	Target Neighborhood Hits	764	Shared Neighborhood Hits	5
SwissProt Accessions	P49711	Gene names	CTCF
Domain Architecture
Description	Transcriptional repressor CTCF (CCCTC-binding factor) (CTCFL paralog) (11-zinc finger protein).

M4K4_HUMAN
NC score	-0.005119 (rank : 125)	θ value	3.0926 (rank : 84)
Query Neighborhood Hits	123	Target Neighborhood Hits	1589	Shared Neighborhood Hits	12
SwissProt Accessions	O95819, O75172, Q9NST7	Gene names	MAP4K4, HGK, KIAA0687, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

STK6_HUMAN
NC score	-0.005186 (rank : 126)	θ value	3.0926 (rank : 86)
Query Neighborhood Hits	123	Target Neighborhood Hits	916	Shared Neighborhood Hits	8
SwissProt Accessions	O14965, O60445, O75873, Q9BQD6, Q9UPG5	Gene names	STK6, AIK, ARK1, AURA, BTAK, STK15
Domain Architecture
Description	Serine/threonine-protein kinase 6 (EC 2.7.11.1) (Serine/threonine kinase 15) (Aurora/IPL1-related kinase 1) (Aurora-related kinase 1) (hARK1) (Aurora-A) (Breast-tumor-amplified kinase).