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Network neighborhood for query Sequence : PRS4_HUMAN

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PRS4_HUMAN
SwissProt Accessions	P62191, P49014, Q03527, Q6IAW0, Q96AZ3	Gene names	PSMC1
Domain Architecture
Description	26S protease regulatory subunit 4 (P26s4) (Proteasome 26S subunit ATPase 1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PRS4_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	84	Target Neighborhood Hits	84	Shared Neighborhood Hits	84
SwissProt Accessions	P62191, P49014, Q03527, Q6IAW0, Q96AZ3	Gene names	PSMC1
Domain Architecture
Description	26S protease regulatory subunit 4 (P26s4) (Proteasome 26S subunit ATPase 1).

PRS4_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 2)
Query Neighborhood Hits	84	Target Neighborhood Hits	84	Shared Neighborhood Hits	84
SwissProt Accessions	P62192, P49014, Q03527, Q96AZ3	Gene names	Psmc1
Domain Architecture
Description	26S protease regulatory subunit 4 (P26s4) (Proteasome 26S subunit ATPase 1).

PRS6B_HUMAN
θ value	3.0981e-109 (rank : 3)	NC score	0.991012 (rank : 3)
Query Neighborhood Hits	84	Target Neighborhood Hits	85	Shared Neighborhood Hits	57
SwissProt Accessions	P43686, Q96FV5, Q9UBM3, Q9UEX3	Gene names	PSMC4, TBP7
Domain Architecture
Description	26S protease regulatory subunit 6B (Proteasome 26S subunit ATPase 4) (MIP224) (MB67-interacting protein) (TAT-binding protein 7) (TBP-7).

PRS6B_MOUSE
θ value	1.87955e-106 (rank : 4)	NC score	0.990611 (rank : 4)
Query Neighborhood Hits	84	Target Neighborhood Hits	89	Shared Neighborhood Hits	57
SwissProt Accessions	P54775	Gene names	Psmc4, Tbp7
Domain Architecture
Description	26S protease regulatory subunit 6B (Proteasome 26S subunit ATPase 4) (MIP224) (MB67-interacting protein) (TAT-binding protein 7) (TBP-7) (CIP21).

PRS6A_HUMAN
θ value	3.32542e-95 (rank : 5)	NC score	0.988391 (rank : 8)
Query Neighborhood Hits	84	Target Neighborhood Hits	87	Shared Neighborhood Hits	62
SwissProt Accessions	P17980, Q96HD3	Gene names	PSMC3, TBP1
Domain Architecture
Description	26S protease regulatory subunit 6A (Proteasome 26S subunit ATPase 3) (TAT-binding protein 1) (TBP-1) (Proteasome subunit P50).

PRS8_HUMAN
θ value	3.32542e-95 (rank : 6)	NC score	0.989284 (rank : 5)
Query Neighborhood Hits	84	Target Neighborhood Hits	117	Shared Neighborhood Hits	66
SwissProt Accessions	P62195, O35051, O43208, P47210, P52915, P52916	Gene names	PSMC5, SUG1
Domain Architecture
Description	26S protease regulatory subunit 8 (Proteasome 26S subunit ATPase 5) (Proteasome subunit p45) (p45/SUG) (Thyroid hormone receptor- interacting protein 1) (TRIP1).

PRS8_MOUSE
θ value	3.32542e-95 (rank : 7)	NC score	0.989284 (rank : 6)
Query Neighborhood Hits	84	Target Neighborhood Hits	117	Shared Neighborhood Hits	66
SwissProt Accessions	P62196, O35051, P47210, P52915, P52916, Q3UL51, Q9CWN5	Gene names	Psmc5, Sug1
Domain Architecture
Description	26S protease regulatory subunit 8 (Proteasome 26S subunit ATPase 5) (Proteasome subunit p45) (p45/SUG) (mSUG1).

PRS6A_MOUSE
θ value	4.34313e-95 (rank : 8)	NC score	0.988567 (rank : 7)
Query Neighborhood Hits	84	Target Neighborhood Hits	85	Shared Neighborhood Hits	62
SwissProt Accessions	O88685	Gene names	Psmc3, Tbp1
Domain Architecture
Description	26S protease regulatory subunit 6A (Proteasome 26S subunit ATPase 3) (TAT-binding protein 1) (TBP-1).

PRS7_HUMAN
θ value	1.40038e-85 (rank : 9)	NC score	0.987690 (rank : 9)
Query Neighborhood Hits	84	Target Neighborhood Hits	66	Shared Neighborhood Hits	63
SwissProt Accessions	P35998	Gene names	PSMC2, MSS1
Domain Architecture
Description	26S protease regulatory subunit 7 (Proteasome 26S subunit ATPase 2) (Protein MSS1).

PRS7_MOUSE
θ value	1.40038e-85 (rank : 10)	NC score	0.987679 (rank : 10)
Query Neighborhood Hits	84	Target Neighborhood Hits	67	Shared Neighborhood Hits	63
SwissProt Accessions	P46471, O08531, Q3TGX5, Q9DBA1	Gene names	Psmc2, Mss1
Domain Architecture
Description	26S protease regulatory subunit 7 (Proteasome 26S subunit ATPase 2) (Protein MSS1).

PRS10_HUMAN
θ value	3.81361e-83 (rank : 11)	NC score	0.987233 (rank : 11)
Query Neighborhood Hits	84	Target Neighborhood Hits	95	Shared Neighborhood Hits	65
SwissProt Accessions	P62333, P49719, Q6IBU3, Q92524	Gene names	PSMC6, SUG2
Domain Architecture
Description	26S protease regulatory subunit S10B (Proteasome subunit p42) (Proteasome 26S subunit ATPase 6).

PRS10_MOUSE
θ value	3.81361e-83 (rank : 12)	NC score	0.987233 (rank : 12)
Query Neighborhood Hits	84	Target Neighborhood Hits	95	Shared Neighborhood Hits	65
SwissProt Accessions	P62334, P49719, Q3TKK1, Q810A6, Q92524, Q9CXH9	Gene names	Psmc6, Sug2
Domain Architecture
Description	26S protease regulatory subunit S10B (Proteasome subunit p42) (Proteasome 26S subunit ATPase 6).

TERA_HUMAN
θ value	1.15626e-55 (rank : 13)	NC score	0.953555 (rank : 13)
Query Neighborhood Hits	84	Target Neighborhood Hits	76	Shared Neighborhood Hits	66
SwissProt Accessions	P55072, Q969G7	Gene names	VCP
Domain Architecture
Description	Transitional endoplasmic reticulum ATPase (TER ATPase) (15S Mg(2+)- ATPase p97 subunit) (Valosin-containing protein) (VCP).

TERA_MOUSE
θ value	1.51013e-55 (rank : 14)	NC score	0.953504 (rank : 14)
Query Neighborhood Hits	84	Target Neighborhood Hits	76	Shared Neighborhood Hits	66
SwissProt Accessions	Q01853	Gene names	Vcp
Domain Architecture
Description	Transitional endoplasmic reticulum ATPase (TER ATPase) (15S Mg(2+)- ATPase p97 subunit) (Valosin-containing protein) (VCP).

AFG31_MOUSE
θ value	2.49495e-50 (rank : 15)	NC score	0.946937 (rank : 16)
Query Neighborhood Hits	84	Target Neighborhood Hits	74	Shared Neighborhood Hits	62
SwissProt Accessions	Q920A7	Gene names	Afg3l1
Domain Architecture
Description	AFG3-like protein 1 (EC 3.4.24.-).

AFG32_HUMAN
θ value	3.2585e-50 (rank : 16)	NC score	0.943359 (rank : 18)
Query Neighborhood Hits	84	Target Neighborhood Hits	72	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Y4W6	Gene names	AFG3L2
Domain Architecture
Description	AFG3-like protein 2 (EC 3.4.24.-) (Paraplegin-like protein).

AFG32_MOUSE
θ value	5.55816e-50 (rank : 17)	NC score	0.943085 (rank : 19)
Query Neighborhood Hits	84	Target Neighborhood Hits	73	Shared Neighborhood Hits	62
SwissProt Accessions	Q8JZQ2	Gene names	Afg3l2
Domain Architecture	No domain graphic available
Description	AFG3-like protein 2 (EC 3.4.24.-).

ATAD2_HUMAN
θ value	1.51363e-47 (rank : 18)	NC score	0.880839 (rank : 41)
Query Neighborhood Hits	84	Target Neighborhood Hits	322	Shared Neighborhood Hits	59
SwissProt Accessions	Q6PL18, Q658P2, Q68CQ0, Q6PJV6, Q8N890, Q9UHS5	Gene names	ATAD2
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 2.

ATAD2_MOUSE
θ value	1.28137e-46 (rank : 19)	NC score	0.897974 (rank : 40)
Query Neighborhood Hits	84	Target Neighborhood Hits	167	Shared Neighborhood Hits	57
SwissProt Accessions	Q8CDM1	Gene names	Atad2
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 2.

SPG7_HUMAN
θ value	1.12253e-42 (rank : 20)	NC score	0.945552 (rank : 17)
Query Neighborhood Hits	84	Target Neighborhood Hits	71	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UQ90, O75756, Q96IB0	Gene names	SPG7, CAR, CMAR, PGN
Domain Architecture
Description	Paraplegin (EC 3.4.24.-) (Spastic paraplegia protein 7).

NVL_MOUSE
θ value	2.50074e-42 (rank : 21)	NC score	0.940482 (rank : 20)
Query Neighborhood Hits	84	Target Neighborhood Hits	110	Shared Neighborhood Hits	64
SwissProt Accessions	Q9DBY8, Q3USC4, Q8BW27, Q8K2B5	Gene names	Nvl
Domain Architecture
Description	Nuclear valosin-containing protein-like (Nuclear VCP-like protein) (NVLp).

NVL_HUMAN
θ value	4.2656e-42 (rank : 22)	NC score	0.939983 (rank : 21)
Query Neighborhood Hits	84	Target Neighborhood Hits	112	Shared Neighborhood Hits	65
SwissProt Accessions	O15381, Q96EM7	Gene names	NVL
Domain Architecture
Description	Nuclear valosin-containing protein-like (Nuclear VCP-like protein) (NVLp).

PEX1_HUMAN
θ value	9.50281e-42 (rank : 23)	NC score	0.948081 (rank : 15)
Query Neighborhood Hits	84	Target Neighborhood Hits	98	Shared Neighborhood Hits	63
SwissProt Accessions	O43933, Q96S71, Q96S72, Q96S73, Q99994	Gene names	PEX1
Domain Architecture
Description	Peroxisome biogenesis factor 1 (Peroxin-1) (Peroxisome biogenesis disorder protein 1).

PEX6_MOUSE
θ value	1.2411e-41 (rank : 24)	NC score	0.934074 (rank : 26)
Query Neighborhood Hits	84	Target Neighborhood Hits	94	Shared Neighborhood Hits	63
SwissProt Accessions	Q99LC9, Q6YNQ9	Gene names	Pex6
Domain Architecture	No domain graphic available
Description	Peroxisome assembly factor 2 (PAF-2) (Peroxisomal-type ATPase 1) (Peroxin-6) (Peroxisomal biogenesis factor 6).

PEX6_HUMAN
θ value	2.11701e-41 (rank : 25)	NC score	0.934167 (rank : 25)
Query Neighborhood Hits	84	Target Neighborhood Hits	99	Shared Neighborhood Hits	64
SwissProt Accessions	Q13608, Q8WYQ2, Q99476	Gene names	PEX6, PXAAA1
Domain Architecture
Description	Peroxisome assembly factor 2 (PAF-2) (Peroxisomal-type ATPase 1) (Peroxin-6) (Peroxisomal biogenesis factor 6).

KTNA1_HUMAN
θ value	1.51715e-39 (rank : 26)	NC score	0.923488 (rank : 32)
Query Neighborhood Hits	84	Target Neighborhood Hits	117	Shared Neighborhood Hits	64
SwissProt Accessions	O75449, Q5TFA8, Q5TFA9, Q86VN2, Q9NU52	Gene names	KATNA1
Domain Architecture	No domain graphic available
Description	Katanin p60 ATPase-containing subunit A1 (EC 3.6.4.3) (Katanin p60 subunit A1) (p60 katanin).

KTNA1_MOUSE
θ value	1.98146e-39 (rank : 27)	NC score	0.921292 (rank : 33)
Query Neighborhood Hits	84	Target Neighborhood Hits	123	Shared Neighborhood Hits	64
SwissProt Accessions	Q9WV86	Gene names	Katna1
Domain Architecture	No domain graphic available
Description	Katanin p60 ATPase-containing subunit A1 (EC 3.6.4.3) (Katanin p60 subunit A1) (p60 katanin) (Lipotransin).

YMEL1_MOUSE
θ value	1.98146e-39 (rank : 28)	NC score	0.936398 (rank : 24)
Query Neighborhood Hits	84	Target Neighborhood Hits	76	Shared Neighborhood Hits	59
SwissProt Accessions	O88967, Q7TNN5	Gene names	Yme1l1
Domain Architecture
Description	ATP-dependent metalloprotease YME1L1 (EC 3.4.24.-) (YME1-like protein 1) (ATP-dependent metalloprotease FtsH1).

YMEL1_HUMAN
θ value	2.58786e-39 (rank : 29)	NC score	0.932334 (rank : 27)
Query Neighborhood Hits	84	Target Neighborhood Hits	73	Shared Neighborhood Hits	59
SwissProt Accessions	Q96TA2, Q9H1Q0, Q9UMR9	Gene names	YME1L1, FTSH1, YME1L
Domain Architecture
Description	ATP-dependent metalloprotease YME1L1 (EC 3.4.24.-) (YME1-like protein 1) (ATP-dependent metalloprotease FtsH1) (Meg-4) (Presenilin- associated metalloprotease) (PAMP).

KATL1_HUMAN
θ value	4.88048e-38 (rank : 30)	NC score	0.925919 (rank : 28)
Query Neighborhood Hits	84	Target Neighborhood Hits	80	Shared Neighborhood Hits	65
SwissProt Accessions	Q9BW62	Gene names	KATNAL1
Domain Architecture	No domain graphic available
Description	Katanin p60 ATPase-containing subunit A-like 1 (EC 3.6.4.3) (Katanin p60 subunit A-like 1) (p60 katanin-like 1).

KATL1_MOUSE
θ value	4.88048e-38 (rank : 31)	NC score	0.925821 (rank : 29)
Query Neighborhood Hits	84	Target Neighborhood Hits	77	Shared Neighborhood Hits	65
SwissProt Accessions	Q8K0T4	Gene names	Katnal1
Domain Architecture	No domain graphic available
Description	Katanin p60 ATPase-containing subunit A-like 1 (EC 3.6.4.3) (Katanin p60 subunit A-like 1) (p60 katanin-like 1).

NSF_MOUSE
θ value	1.12514e-34 (rank : 32)	NC score	0.925002 (rank : 30)
Query Neighborhood Hits	84	Target Neighborhood Hits	73	Shared Neighborhood Hits	63
SwissProt Accessions	P46460	Gene names	Nsf, Skd2
Domain Architecture
Description	Vesicle-fusing ATPase (EC 3.6.4.6) (Vesicular-fusion protein NSF) (N- ethylmaleimide sensitive fusion protein) (NEM-sensitive fusion protein) (SKD2 protein).

NSF_HUMAN
θ value	5.584e-34 (rank : 33)	NC score	0.924363 (rank : 31)
Query Neighborhood Hits	84	Target Neighborhood Hits	74	Shared Neighborhood Hits	66
SwissProt Accessions	P46459, Q9UKZ2	Gene names	NSF
Domain Architecture
Description	Vesicle-fusing ATPase (EC 3.6.4.6) (Vesicular-fusion protein NSF) (N- ethylmaleimide sensitive fusion protein) (NEM-sensitive fusion protein).

SPAST_HUMAN
θ value	7.29293e-34 (rank : 34)	NC score	0.917842 (rank : 34)
Query Neighborhood Hits	84	Target Neighborhood Hits	100	Shared Neighborhood Hits	61
SwissProt Accessions	Q9UBP0, Q9UPR9	Gene names	SPAST, KIAA1083, SPG4
Domain Architecture
Description	Spastin.

SPAST_MOUSE
θ value	2.12192e-33 (rank : 35)	NC score	0.916139 (rank : 35)
Query Neighborhood Hits	84	Target Neighborhood Hits	138	Shared Neighborhood Hits	62
SwissProt Accessions	Q9QYY8, Q6ZPY6, Q80VE0, Q9CVK0	Gene names	Spast, Kiaa1083, Spg4
Domain Architecture	No domain graphic available
Description	Spastin.

VPS4A_HUMAN
θ value	4.72714e-33 (rank : 36)	NC score	0.907779 (rank : 38)
Query Neighborhood Hits	84	Target Neighborhood Hits	95	Shared Neighborhood Hits	61
SwissProt Accessions	Q9UN37, Q8TF07, Q9UI03, Q9Y582	Gene names	VPS4A, VPS4
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associating protein 4A (SKD2 protein) (hVPS4) (VPS4-1).

VPS4A_MOUSE
θ value	4.72714e-33 (rank : 37)	NC score	0.907760 (rank : 39)
Query Neighborhood Hits	84	Target Neighborhood Hits	94	Shared Neighborhood Hits	61
SwissProt Accessions	Q8VEJ9, Q3TXT2	Gene names	Vps4a
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associating protein 4A.

VPS4B_MOUSE
θ value	2.34606e-32 (rank : 38)	NC score	0.909757 (rank : 37)
Query Neighborhood Hits	84	Target Neighborhood Hits	86	Shared Neighborhood Hits	60
SwissProt Accessions	P46467, Q91W22, Q9R1C9	Gene names	Vps4b, Skd1
Domain Architecture
Description	Vacuolar protein sorting-associating protein 4B (Protein SKD1).

VPS4B_HUMAN
θ value	5.22648e-32 (rank : 39)	NC score	0.909976 (rank : 36)
Query Neighborhood Hits	84	Target Neighborhood Hits	87	Shared Neighborhood Hits	61
SwissProt Accessions	O75351, Q9GZS7	Gene names	VPS4B, SKD1, VPS42
Domain Architecture
Description	Vacuolar protein sorting-associating protein 4B (Protein SKD1).

ATAD1_HUMAN
θ value	6.82597e-32 (rank : 40)	NC score	0.938061 (rank : 22)
Query Neighborhood Hits	84	Target Neighborhood Hits	75	Shared Neighborhood Hits	65
SwissProt Accessions	Q8NBU5, Q6P4B9, Q8N3G1, Q8WYR9, Q969Y3	Gene names	ATAD1
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 1.

ATAD1_MOUSE
θ value	6.82597e-32 (rank : 41)	NC score	0.938061 (rank : 23)
Query Neighborhood Hits	84	Target Neighborhood Hits	75	Shared Neighborhood Hits	65
SwissProt Accessions	Q9D5T0, Q3U8V2, Q9D7A4	Gene names	Atad1
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 1.

FIGN_MOUSE
θ value	2.51237e-26 (rank : 42)	NC score	0.871587 (rank : 42)
Query Neighborhood Hits	84	Target Neighborhood Hits	165	Shared Neighborhood Hits	55
SwissProt Accessions	Q9ERZ6, Q3TPB0, Q3UP57, Q6PCM0	Gene names	Fign
Domain Architecture	No domain graphic available
Description	Fidgetin.

FIGN_HUMAN
θ value	7.30988e-26 (rank : 43)	NC score	0.866006 (rank : 43)
Query Neighborhood Hits	84	Target Neighborhood Hits	176	Shared Neighborhood Hits	55
SwissProt Accessions	Q5HY92, Q9H6M5, Q9NVZ9	Gene names	FIGN
Domain Architecture	No domain graphic available
Description	Fidgetin.

BCS1_HUMAN
θ value	3.18553e-13 (rank : 44)	NC score	0.723579 (rank : 44)
Query Neighborhood Hits	84	Target Neighborhood Hits	61	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Y276, Q7Z2V7	Gene names	BCS1L, BCS1
Domain Architecture
Description	Mitochondrial chaperone BCS1 (BCS1-like protein) (H-BCS1).

BCS1_MOUSE
θ value	4.16044e-13 (rank : 45)	NC score	0.715340 (rank : 45)
Query Neighborhood Hits	84	Target Neighborhood Hits	64	Shared Neighborhood Hits	52
SwissProt Accessions	Q9CZP5	Gene names	Bcs1l
Domain Architecture
Description	Mitochondrial chaperone BCS1 (BCS1-like protein).

TRP13_MOUSE
θ value	8.11959e-09 (rank : 46)	NC score	0.713040 (rank : 46)
Query Neighborhood Hits	84	Target Neighborhood Hits	81	Shared Neighborhood Hits	58
SwissProt Accessions	Q3UA06, Q3UQG6, Q9CWW8	Gene names	Trip13
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 13 (Thyroid hormone receptor interactor 13) (Trip-13).

ATD3B_HUMAN
θ value	1.38499e-08 (rank : 47)	NC score	0.620855 (rank : 49)
Query Neighborhood Hits	84	Target Neighborhood Hits	340	Shared Neighborhood Hits	63
SwissProt Accessions	Q5T9A4, Q6ZRB5, Q9BUK4, Q9ULE7	Gene names	ATAD3B, KIAA1273
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 3B.

TRP13_HUMAN
θ value	1.80886e-08 (rank : 48)	NC score	0.709378 (rank : 47)
Query Neighborhood Hits	84	Target Neighborhood Hits	81	Shared Neighborhood Hits	59
SwissProt Accessions	Q15645, O15324	Gene names	TRIP13
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 13 (Thyroid hormone receptor interactor 13) (Trip-13) (Human papillomavirus type 16 E1 protein- binding protein) (HPV16 E1 protein-binding protein) (16E1-BP).

ATAD3_MOUSE
θ value	5.26297e-08 (rank : 49)	NC score	0.612743 (rank : 50)
Query Neighborhood Hits	84	Target Neighborhood Hits	326	Shared Neighborhood Hits	64
SwissProt Accessions	Q925I1, Q3UE74, Q69ZM7, Q8C6C6	Gene names	Atad3, Atad3a, Kiaa1273
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 3 (AAA-ATPase TOB3).

ATD3A_HUMAN
θ value	1.53129e-07 (rank : 50)	NC score	0.630170 (rank : 48)
Query Neighborhood Hits	84	Target Neighborhood Hits	248	Shared Neighborhood Hits	62
SwissProt Accessions	Q9NVI7, Q8N275, Q96A50	Gene names	ATAD3A
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 3A.

CLPX_HUMAN
θ value	0.000786445 (rank : 51)	NC score	0.444497 (rank : 51)
Query Neighborhood Hits	84	Target Neighborhood Hits	72	Shared Neighborhood Hits	51
SwissProt Accessions	O76031, Q9H4D9	Gene names	CLPX
Domain Architecture
Description	ATP-dependent Clp protease ATP-binding subunit ClpX-like, mitochondrial precursor.

CLPX_MOUSE
θ value	0.000786445 (rank : 52)	NC score	0.442680 (rank : 52)
Query Neighborhood Hits	84	Target Neighborhood Hits	73	Shared Neighborhood Hits	51
SwissProt Accessions	Q9JHS4, Q9WVD1	Gene names	Clpx
Domain Architecture
Description	ATP-dependent Clp protease ATP-binding subunit ClpX-like, mitochondrial precursor.

WRIP1_MOUSE
θ value	0.00665767 (rank : 53)	NC score	0.262689 (rank : 56)
Query Neighborhood Hits	84	Target Neighborhood Hits	93	Shared Neighborhood Hits	52
SwissProt Accessions	Q91XU0, Q3TCT7, Q6PDF0, Q8BUW5, Q8BWP6, Q8BY55, Q921W3, Q9EQL3	Gene names	Wrnip1, Whip
Domain Architecture	No domain graphic available
Description	ATPase WRNIP1 (Werner helicase-interacting protein 1).

LONM_HUMAN
θ value	0.0193708 (rank : 54)	NC score	0.435324 (rank : 53)
Query Neighborhood Hits	84	Target Neighborhood Hits	130	Shared Neighborhood Hits	59
SwissProt Accessions	P36776, P36777, Q9UQ95	Gene names	PRSS15
Domain Architecture
Description	Lon protease homolog, mitochondrial precursor (EC 3.4.21.-) (Lon protease-like protein) (LONP) (LONHs).

WRIP1_HUMAN
θ value	0.0193708 (rank : 55)	NC score	0.258302 (rank : 57)
Query Neighborhood Hits	84	Target Neighborhood Hits	100	Shared Neighborhood Hits	51
SwissProt Accessions	Q96S55, Q53EP6, Q59ET8, Q5W0E2, Q5W0E4, Q8WV26, Q9H681, Q9NRJ6	Gene names	WRNIP1, WHIP
Domain Architecture	No domain graphic available
Description	ATPase WRNIP1 (Werner helicase-interacting protein 1).

RUVB1_HUMAN
θ value	0.0330416 (rank : 56)	NC score	0.318976 (rank : 54)
Query Neighborhood Hits	84	Target Neighborhood Hits	78	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Y265, Q9BSX9	Gene names	RUVBL1, NMP238, TIP49, TIP49A
Domain Architecture
Description	RuvB-like 1 (EC 3.6.1.-) (49 kDa TATA box-binding protein-interacting protein) (49 kDa TBP-interacting protein) (TIP49a) (Pontin 52) (Nuclear matrix protein 238) (NMP 238) (54 kDa erythrocyte cytosolic protein) (ECP-54) (TIP60-associated protein 54-alpha) (TAP54-alpha).

RUVB1_MOUSE
θ value	0.0330416 (rank : 57)	NC score	0.318937 (rank : 55)
Query Neighborhood Hits	84	Target Neighborhood Hits	78	Shared Neighborhood Hits	59
SwissProt Accessions	P60122, O35753	Gene names	Ruvbl1, Tip49, Tip49a
Domain Architecture
Description	RuvB-like 1 (EC 3.6.1.-) (49 kDa TATA box-binding protein-interacting protein) (49 kDa TBP-interacting protein) (TIP49a) (Pontin 52) (DNA helicase p50).

KAD2_HUMAN
θ value	0.163984 (rank : 58)	NC score	0.037280 (rank : 71)
Query Neighborhood Hits	84	Target Neighborhood Hits	23	Shared Neighborhood Hits	6
SwissProt Accessions	P54819, Q16856, Q5TIF7, Q8TCY2, Q8TCY3	Gene names	AK2, ADK2
Domain Architecture
Description	Adenylate kinase isoenzyme 2, mitochondrial (EC 2.7.4.3) (ATP-AMP transphosphorylase).

ICA69_HUMAN
θ value	0.47712 (rank : 59)	NC score	0.022340 (rank : 75)
Query Neighborhood Hits	84	Target Neighborhood Hits	35	Shared Neighborhood Hits	5
SwissProt Accessions	Q05084, P78506, Q13824	Gene names	ICA1
Domain Architecture
Description	Islet cell autoantigen 1 (69 kDa islet cell autoantigen) (ICA69) (p69) (Islet cell autoantigen p69) (ICAp69).

RFC5_HUMAN
θ value	1.06291 (rank : 60)	NC score	0.078006 (rank : 68)
Query Neighborhood Hits	84	Target Neighborhood Hits	60	Shared Neighborhood Hits	30
SwissProt Accessions	P40937	Gene names	RFC5
Domain Architecture
Description	Replication factor C subunit 5 (Replication factor C 36 kDa subunit) (RF-C 36 kDa subunit) (RFC36) (Activator 1 36 kDa subunit) (A1 36 kDa subunit).

RFC5_MOUSE
θ value	1.06291 (rank : 61)	NC score	0.079422 (rank : 67)
Query Neighborhood Hits	84	Target Neighborhood Hits	58	Shared Neighborhood Hits	32
SwissProt Accessions	Q9D0F6	Gene names	Rfc5
Domain Architecture
Description	Replication factor C subunit 5 (Replication factor C 36 kDa subunit) (RF-C 36 kDa subunit) (RFC36) (Activator 1 36 kDa subunit) (A1 36 kDa subunit).

CKAP5_HUMAN
θ value	1.38821 (rank : 62)	NC score	0.023277 (rank : 74)
Query Neighborhood Hits	84	Target Neighborhood Hits	96	Shared Neighborhood Hits	3
SwissProt Accessions	Q14008, Q14668	Gene names	CKAP5, KIAA0097
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 5 (Colonic and hepatic tumor over- expressed protein) (Ch-TOG protein).

LC7L2_HUMAN
θ value	2.36792 (rank : 63)	NC score	0.013786 (rank : 77)
Query Neighborhood Hits	84	Target Neighborhood Hits	235	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y383, Q8IUP9, Q9NVL3, Q9NVN7, Q9UQN1	Gene names	LUC7L2
Domain Architecture
Description	Putative RNA-binding protein Luc7-like 2.

LC7L2_MOUSE
θ value	2.36792 (rank : 64)	NC score	0.013591 (rank : 78)
Query Neighborhood Hits	84	Target Neighborhood Hits	244	Shared Neighborhood Hits	5
SwissProt Accessions	Q7TNC4, Q99LM5, Q99PC3	Gene names	Luc7l2
Domain Architecture
Description	Putative RNA-binding protein Luc7-like 2 (CGI-74 homolog).

LRC45_HUMAN
θ value	2.36792 (rank : 65)	NC score	0.001797 (rank : 85)
Query Neighborhood Hits	84	Target Neighborhood Hits	933	Shared Neighborhood Hits	9
SwissProt Accessions	Q96CN5	Gene names	LRRC45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

SIN3A_MOUSE
θ value	2.36792 (rank : 66)	NC score	0.010465 (rank : 82)
Query Neighborhood Hits	84	Target Neighborhood Hits	169	Shared Neighborhood Hits	3
SwissProt Accessions	Q60520, Q60820, Q62139, Q62140, Q7TPU8, Q7TSZ2	Gene names	Sin3a
Domain Architecture
Description	Paired amphipathic helix protein Sin3a (Transcriptional corepressor Sin3a) (Histone deacetylase complex subunit Sin3a).

CDC27_HUMAN
θ value	3.0926 (rank : 67)	NC score	0.011458 (rank : 80)
Query Neighborhood Hits	84	Target Neighborhood Hits	139	Shared Neighborhood Hits	3
SwissProt Accessions	P30260, Q16349, Q96F35	Gene names	CDC27
Domain Architecture
Description	Cell division cycle protein 27 homolog (CDC27Hs) (H-NUC).

NCOA7_HUMAN
θ value	3.0926 (rank : 68)	NC score	0.010810 (rank : 81)
Query Neighborhood Hits	84	Target Neighborhood Hits	160	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NI08, Q3LID6, Q4G0V1, Q5TF95, Q6IPQ4, Q6NE83, Q86T89, Q8N1W4	Gene names	NCOA7, ERAP140, ESNA1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 7 (140 kDa estrogen receptor-associated protein) (Estrogen nuclear receptor coactivator 1).

MDN1_HUMAN
θ value	4.03905 (rank : 69)	NC score	0.038758 (rank : 70)
Query Neighborhood Hits	84	Target Neighborhood Hits	662	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

RENT1_MOUSE
θ value	4.03905 (rank : 70)	NC score	0.026915 (rank : 72)
Query Neighborhood Hits	84	Target Neighborhood Hits	54	Shared Neighborhood Hits	9
SwissProt Accessions	Q9EPU0, Q99PR4	Gene names	Upf1, Rent1
Domain Architecture
Description	Regulator of nonsense transcripts 1 (EC 3.6.1.-) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up- frameshift suppressor 1 homolog) (mUpf1).

CCD91_HUMAN
θ value	5.27518 (rank : 71)	NC score	0.001860 (rank : 84)
Query Neighborhood Hits	84	Target Neighborhood Hits	868	Shared Neighborhood Hits	9
SwissProt Accessions	Q7Z6B0, Q68D43, Q6IA78, Q8NEN7, Q9NUW9	Gene names	CCDC91, GGABP
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner) (p56 accessory protein).

IF140_HUMAN
θ value	5.27518 (rank : 72)	NC score	0.012195 (rank : 79)
Query Neighborhood Hits	84	Target Neighborhood Hits	111	Shared Neighborhood Hits	3
SwissProt Accessions	Q96RY7, O60332	Gene names	IFT140, KIAA0590, WDTC2
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 140 homolog (WD and tetratricopeptide repeats protein 2).

PALM_MOUSE
θ value	5.27518 (rank : 73)	NC score	0.009454 (rank : 83)
Query Neighborhood Hits	84	Target Neighborhood Hits	228	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z0P4, Q9Z0P3	Gene names	Palm
Domain Architecture
Description	Paralemmin.

RENT1_HUMAN
θ value	5.27518 (rank : 74)	NC score	0.025380 (rank : 73)
Query Neighborhood Hits	84	Target Neighborhood Hits	51	Shared Neighborhood Hits	9
SwissProt Accessions	Q92900, O00239, O43343, Q86Z25, Q92842	Gene names	UPF1, KIAA0221, RENT1
Domain Architecture
Description	Regulator of nonsense transcripts 1 (EC 3.6.1.-) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up- frameshift suppressor 1 homolog) (hUpf1).

RUVB2_HUMAN
θ value	5.27518 (rank : 75)	NC score	0.122403 (rank : 58)
Query Neighborhood Hits	84	Target Neighborhood Hits	43	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Y230, Q6PK27, Q9Y361	Gene names	RUVBL2, TIP48, TIP49B
Domain Architecture
Description	RuvB-like 2 (EC 3.6.1.-) (48 kDa TATA box-binding protein-interacting protein) (48 kDa TBP-interacting protein) (TIP49b) (Repressing pontin 52) (Reptin 52) (51 kDa erythrocyte cytosolic protein) (ECP-51) (TIP60-associated protein 54-beta) (TAP54-beta).

RUVB2_MOUSE
θ value	5.27518 (rank : 76)	NC score	0.119852 (rank : 59)
Query Neighborhood Hits	84	Target Neighborhood Hits	42	Shared Neighborhood Hits	38
SwissProt Accessions	Q9WTM5	Gene names	Ruvbl2
Domain Architecture
Description	RuvB-like 2 (EC 3.6.1.-) (p47 protein).

KAD2_MOUSE
θ value	6.88961 (rank : 77)	NC score	0.018633 (rank : 76)
Query Neighborhood Hits	84	Target Neighborhood Hits	21	Shared Neighborhood Hits	6
SwissProt Accessions	Q9WTP6, Q3TKI6, Q9CY37	Gene names	Ak2, Ak-2
Domain Architecture
Description	Adenylate kinase isoenzyme 2, mitochondrial (EC 2.7.4.3) (ATP-AMP transphosphorylase).

SYNE2_HUMAN
θ value	6.88961 (rank : 78)	NC score	-0.001374 (rank : 87)
Query Neighborhood Hits	84	Target Neighborhood Hits	1323	Shared Neighborhood Hits	12
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

THNSL_HUMAN
θ value	6.88961 (rank : 79)	NC score	0.104392 (rank : 62)
Query Neighborhood Hits	84	Target Neighborhood Hits	47	Shared Neighborhood Hits	36
SwissProt Accessions	Q8IYQ7, Q5VV21	Gene names	THNSL1
Domain Architecture	No domain graphic available
Description	Threonine synthase-like 1.

KAD6_HUMAN
θ value	8.99809 (rank : 80)	NC score	0.093553 (rank : 65)
Query Neighborhood Hits	84	Target Neighborhood Hits	46	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Y3D8	Gene names	AK6
Domain Architecture
Description	Adenylate kinase isoenzyme 6 (EC 2.7.4.3) (ATP-AMP transphosphorylase 6).

P55G_HUMAN
θ value	8.99809 (rank : 81)	NC score	0.000590 (rank : 86)
Query Neighborhood Hits	84	Target Neighborhood Hits	451	Shared Neighborhood Hits	4
SwissProt Accessions	Q92569, O60482	Gene names	PIK3R3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

RFC1_HUMAN
θ value	8.99809 (rank : 82)	NC score	0.101199 (rank : 63)
Query Neighborhood Hits	84	Target Neighborhood Hits	352	Shared Neighborhood Hits	45
SwissProt Accessions	P35251, Q5XKF5, Q6PKU0, Q86V41, Q86V46	Gene names	RFC1, RFC140
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (DNA-binding protein PO-GA).

RFC1_MOUSE
θ value	8.99809 (rank : 83)	NC score	0.114273 (rank : 60)
Query Neighborhood Hits	84	Target Neighborhood Hits	290	Shared Neighborhood Hits	46
SwissProt Accessions	P35601	Gene names	Rfc1, Ibf-1, Recc1
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (A1-P145) (Differentiation- specific element-binding protein) (ISRE-binding protein).

THNSL_MOUSE
θ value	8.99809 (rank : 84)	NC score	0.106712 (rank : 61)
Query Neighborhood Hits	84	Target Neighborhood Hits	47	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BH55	Gene names	Thnsl1
Domain Architecture	No domain graphic available
Description	Threonine synthase-like 1.

KAD6_MOUSE
θ value	θ > 10 (rank : 85)	NC score	0.071031 (rank : 69)
Query Neighborhood Hits	84	Target Neighborhood Hits	34	Shared Neighborhood Hits	22
SwissProt Accessions	Q8VCP8	Gene names	Ak6
Domain Architecture	No domain graphic available
Description	Adenylate kinase isoenzyme 6 (EC 2.7.4.3) (ATP-AMP transphosphorylase 6).

RFC4_HUMAN
θ value	θ > 10 (rank : 86)	NC score	0.101004 (rank : 64)
Query Neighborhood Hits	84	Target Neighborhood Hits	64	Shared Neighborhood Hits	40
SwissProt Accessions	P35249, Q6FHX7	Gene names	RFC4
Domain Architecture
Description	Replication factor C subunit 4 (Replication factor C 37 kDa subunit) (RF-C 37 kDa subunit) (RFC37) (Activator 1 37 kDa subunit) (A1 37 kDa subunit).

RFC4_MOUSE
θ value	θ > 10 (rank : 87)	NC score	0.089972 (rank : 66)
Query Neighborhood Hits	84	Target Neighborhood Hits	65	Shared Neighborhood Hits	40
SwissProt Accessions	Q99J62	Gene names	Rfc4
Domain Architecture	No domain graphic available
Description	Replication factor C subunit 4.

Hits sorted by NC score

PRS4_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	84	Target Neighborhood Hits	84	Shared Neighborhood Hits	84
SwissProt Accessions	P62191, P49014, Q03527, Q6IAW0, Q96AZ3	Gene names	PSMC1
Domain Architecture
Description	26S protease regulatory subunit 4 (P26s4) (Proteasome 26S subunit ATPase 1).

PRS4_MOUSE
NC score	0.999962 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	84	Target Neighborhood Hits	84	Shared Neighborhood Hits	84
SwissProt Accessions	P62192, P49014, Q03527, Q96AZ3	Gene names	Psmc1
Domain Architecture
Description	26S protease regulatory subunit 4 (P26s4) (Proteasome 26S subunit ATPase 1).

PRS6B_HUMAN
NC score	0.991012 (rank : 3)	θ value	3.0981e-109 (rank : 3)
Query Neighborhood Hits	84	Target Neighborhood Hits	85	Shared Neighborhood Hits	57
SwissProt Accessions	P43686, Q96FV5, Q9UBM3, Q9UEX3	Gene names	PSMC4, TBP7
Domain Architecture
Description	26S protease regulatory subunit 6B (Proteasome 26S subunit ATPase 4) (MIP224) (MB67-interacting protein) (TAT-binding protein 7) (TBP-7).

PRS6B_MOUSE
NC score	0.990611 (rank : 4)	θ value	1.87955e-106 (rank : 4)
Query Neighborhood Hits	84	Target Neighborhood Hits	89	Shared Neighborhood Hits	57
SwissProt Accessions	P54775	Gene names	Psmc4, Tbp7
Domain Architecture
Description	26S protease regulatory subunit 6B (Proteasome 26S subunit ATPase 4) (MIP224) (MB67-interacting protein) (TAT-binding protein 7) (TBP-7) (CIP21).

PRS8_HUMAN
NC score	0.989284 (rank : 5)	θ value	3.32542e-95 (rank : 6)
Query Neighborhood Hits	84	Target Neighborhood Hits	117	Shared Neighborhood Hits	66
SwissProt Accessions	P62195, O35051, O43208, P47210, P52915, P52916	Gene names	PSMC5, SUG1
Domain Architecture
Description	26S protease regulatory subunit 8 (Proteasome 26S subunit ATPase 5) (Proteasome subunit p45) (p45/SUG) (Thyroid hormone receptor- interacting protein 1) (TRIP1).

PRS8_MOUSE
NC score	0.989284 (rank : 6)	θ value	3.32542e-95 (rank : 7)
Query Neighborhood Hits	84	Target Neighborhood Hits	117	Shared Neighborhood Hits	66
SwissProt Accessions	P62196, O35051, P47210, P52915, P52916, Q3UL51, Q9CWN5	Gene names	Psmc5, Sug1
Domain Architecture
Description	26S protease regulatory subunit 8 (Proteasome 26S subunit ATPase 5) (Proteasome subunit p45) (p45/SUG) (mSUG1).

PRS6A_MOUSE
NC score	0.988567 (rank : 7)	θ value	4.34313e-95 (rank : 8)
Query Neighborhood Hits	84	Target Neighborhood Hits	85	Shared Neighborhood Hits	62
SwissProt Accessions	O88685	Gene names	Psmc3, Tbp1
Domain Architecture
Description	26S protease regulatory subunit 6A (Proteasome 26S subunit ATPase 3) (TAT-binding protein 1) (TBP-1).

PRS6A_HUMAN
NC score	0.988391 (rank : 8)	θ value	3.32542e-95 (rank : 5)
Query Neighborhood Hits	84	Target Neighborhood Hits	87	Shared Neighborhood Hits	62
SwissProt Accessions	P17980, Q96HD3	Gene names	PSMC3, TBP1
Domain Architecture
Description	26S protease regulatory subunit 6A (Proteasome 26S subunit ATPase 3) (TAT-binding protein 1) (TBP-1) (Proteasome subunit P50).

PRS7_HUMAN
NC score	0.987690 (rank : 9)	θ value	1.40038e-85 (rank : 9)
Query Neighborhood Hits	84	Target Neighborhood Hits	66	Shared Neighborhood Hits	63
SwissProt Accessions	P35998	Gene names	PSMC2, MSS1
Domain Architecture
Description	26S protease regulatory subunit 7 (Proteasome 26S subunit ATPase 2) (Protein MSS1).

PRS7_MOUSE
NC score	0.987679 (rank : 10)	θ value	1.40038e-85 (rank : 10)
Query Neighborhood Hits	84	Target Neighborhood Hits	67	Shared Neighborhood Hits	63
SwissProt Accessions	P46471, O08531, Q3TGX5, Q9DBA1	Gene names	Psmc2, Mss1
Domain Architecture
Description	26S protease regulatory subunit 7 (Proteasome 26S subunit ATPase 2) (Protein MSS1).

PRS10_HUMAN
NC score	0.987233 (rank : 11)	θ value	3.81361e-83 (rank : 11)
Query Neighborhood Hits	84	Target Neighborhood Hits	95	Shared Neighborhood Hits	65
SwissProt Accessions	P62333, P49719, Q6IBU3, Q92524	Gene names	PSMC6, SUG2
Domain Architecture
Description	26S protease regulatory subunit S10B (Proteasome subunit p42) (Proteasome 26S subunit ATPase 6).

PRS10_MOUSE
NC score	0.987233 (rank : 12)	θ value	3.81361e-83 (rank : 12)
Query Neighborhood Hits	84	Target Neighborhood Hits	95	Shared Neighborhood Hits	65
SwissProt Accessions	P62334, P49719, Q3TKK1, Q810A6, Q92524, Q9CXH9	Gene names	Psmc6, Sug2
Domain Architecture
Description	26S protease regulatory subunit S10B (Proteasome subunit p42) (Proteasome 26S subunit ATPase 6).

TERA_HUMAN
NC score	0.953555 (rank : 13)	θ value	1.15626e-55 (rank : 13)
Query Neighborhood Hits	84	Target Neighborhood Hits	76	Shared Neighborhood Hits	66
SwissProt Accessions	P55072, Q969G7	Gene names	VCP
Domain Architecture
Description	Transitional endoplasmic reticulum ATPase (TER ATPase) (15S Mg(2+)- ATPase p97 subunit) (Valosin-containing protein) (VCP).

TERA_MOUSE
NC score	0.953504 (rank : 14)	θ value	1.51013e-55 (rank : 14)
Query Neighborhood Hits	84	Target Neighborhood Hits	76	Shared Neighborhood Hits	66
SwissProt Accessions	Q01853	Gene names	Vcp
Domain Architecture
Description	Transitional endoplasmic reticulum ATPase (TER ATPase) (15S Mg(2+)- ATPase p97 subunit) (Valosin-containing protein) (VCP).

PEX1_HUMAN
NC score	0.948081 (rank : 15)	θ value	9.50281e-42 (rank : 23)
Query Neighborhood Hits	84	Target Neighborhood Hits	98	Shared Neighborhood Hits	63
SwissProt Accessions	O43933, Q96S71, Q96S72, Q96S73, Q99994	Gene names	PEX1
Domain Architecture
Description	Peroxisome biogenesis factor 1 (Peroxin-1) (Peroxisome biogenesis disorder protein 1).

AFG31_MOUSE
NC score	0.946937 (rank : 16)	θ value	2.49495e-50 (rank : 15)
Query Neighborhood Hits	84	Target Neighborhood Hits	74	Shared Neighborhood Hits	62
SwissProt Accessions	Q920A7	Gene names	Afg3l1
Domain Architecture
Description	AFG3-like protein 1 (EC 3.4.24.-).

SPG7_HUMAN
NC score	0.945552 (rank : 17)	θ value	1.12253e-42 (rank : 20)
Query Neighborhood Hits	84	Target Neighborhood Hits	71	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UQ90, O75756, Q96IB0	Gene names	SPG7, CAR, CMAR, PGN
Domain Architecture
Description	Paraplegin (EC 3.4.24.-) (Spastic paraplegia protein 7).

AFG32_HUMAN
NC score	0.943359 (rank : 18)	θ value	3.2585e-50 (rank : 16)
Query Neighborhood Hits	84	Target Neighborhood Hits	72	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Y4W6	Gene names	AFG3L2
Domain Architecture
Description	AFG3-like protein 2 (EC 3.4.24.-) (Paraplegin-like protein).

AFG32_MOUSE
NC score	0.943085 (rank : 19)	θ value	5.55816e-50 (rank : 17)
Query Neighborhood Hits	84	Target Neighborhood Hits	73	Shared Neighborhood Hits	62
SwissProt Accessions	Q8JZQ2	Gene names	Afg3l2
Domain Architecture	No domain graphic available
Description	AFG3-like protein 2 (EC 3.4.24.-).

NVL_MOUSE
NC score	0.940482 (rank : 20)	θ value	2.50074e-42 (rank : 21)
Query Neighborhood Hits	84	Target Neighborhood Hits	110	Shared Neighborhood Hits	64
SwissProt Accessions	Q9DBY8, Q3USC4, Q8BW27, Q8K2B5	Gene names	Nvl
Domain Architecture
Description	Nuclear valosin-containing protein-like (Nuclear VCP-like protein) (NVLp).

NVL_HUMAN
NC score	0.939983 (rank : 21)	θ value	4.2656e-42 (rank : 22)
Query Neighborhood Hits	84	Target Neighborhood Hits	112	Shared Neighborhood Hits	65
SwissProt Accessions	O15381, Q96EM7	Gene names	NVL
Domain Architecture
Description	Nuclear valosin-containing protein-like (Nuclear VCP-like protein) (NVLp).

ATAD1_HUMAN
NC score	0.938061 (rank : 22)	θ value	6.82597e-32 (rank : 40)
Query Neighborhood Hits	84	Target Neighborhood Hits	75	Shared Neighborhood Hits	65
SwissProt Accessions	Q8NBU5, Q6P4B9, Q8N3G1, Q8WYR9, Q969Y3	Gene names	ATAD1
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 1.

ATAD1_MOUSE
NC score	0.938061 (rank : 23)	θ value	6.82597e-32 (rank : 41)
Query Neighborhood Hits	84	Target Neighborhood Hits	75	Shared Neighborhood Hits	65
SwissProt Accessions	Q9D5T0, Q3U8V2, Q9D7A4	Gene names	Atad1
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 1.

YMEL1_MOUSE
NC score	0.936398 (rank : 24)	θ value	1.98146e-39 (rank : 28)
Query Neighborhood Hits	84	Target Neighborhood Hits	76	Shared Neighborhood Hits	59
SwissProt Accessions	O88967, Q7TNN5	Gene names	Yme1l1
Domain Architecture
Description	ATP-dependent metalloprotease YME1L1 (EC 3.4.24.-) (YME1-like protein 1) (ATP-dependent metalloprotease FtsH1).

PEX6_HUMAN
NC score	0.934167 (rank : 25)	θ value	2.11701e-41 (rank : 25)
Query Neighborhood Hits	84	Target Neighborhood Hits	99	Shared Neighborhood Hits	64
SwissProt Accessions	Q13608, Q8WYQ2, Q99476	Gene names	PEX6, PXAAA1
Domain Architecture
Description	Peroxisome assembly factor 2 (PAF-2) (Peroxisomal-type ATPase 1) (Peroxin-6) (Peroxisomal biogenesis factor 6).

PEX6_MOUSE
NC score	0.934074 (rank : 26)	θ value	1.2411e-41 (rank : 24)
Query Neighborhood Hits	84	Target Neighborhood Hits	94	Shared Neighborhood Hits	63
SwissProt Accessions	Q99LC9, Q6YNQ9	Gene names	Pex6
Domain Architecture	No domain graphic available
Description	Peroxisome assembly factor 2 (PAF-2) (Peroxisomal-type ATPase 1) (Peroxin-6) (Peroxisomal biogenesis factor 6).

YMEL1_HUMAN
NC score	0.932334 (rank : 27)	θ value	2.58786e-39 (rank : 29)
Query Neighborhood Hits	84	Target Neighborhood Hits	73	Shared Neighborhood Hits	59
SwissProt Accessions	Q96TA2, Q9H1Q0, Q9UMR9	Gene names	YME1L1, FTSH1, YME1L
Domain Architecture
Description	ATP-dependent metalloprotease YME1L1 (EC 3.4.24.-) (YME1-like protein 1) (ATP-dependent metalloprotease FtsH1) (Meg-4) (Presenilin- associated metalloprotease) (PAMP).

KATL1_HUMAN
NC score	0.925919 (rank : 28)	θ value	4.88048e-38 (rank : 30)
Query Neighborhood Hits	84	Target Neighborhood Hits	80	Shared Neighborhood Hits	65
SwissProt Accessions	Q9BW62	Gene names	KATNAL1
Domain Architecture	No domain graphic available
Description	Katanin p60 ATPase-containing subunit A-like 1 (EC 3.6.4.3) (Katanin p60 subunit A-like 1) (p60 katanin-like 1).

KATL1_MOUSE
NC score	0.925821 (rank : 29)	θ value	4.88048e-38 (rank : 31)
Query Neighborhood Hits	84	Target Neighborhood Hits	77	Shared Neighborhood Hits	65
SwissProt Accessions	Q8K0T4	Gene names	Katnal1
Domain Architecture	No domain graphic available
Description	Katanin p60 ATPase-containing subunit A-like 1 (EC 3.6.4.3) (Katanin p60 subunit A-like 1) (p60 katanin-like 1).

NSF_MOUSE
NC score	0.925002 (rank : 30)	θ value	1.12514e-34 (rank : 32)
Query Neighborhood Hits	84	Target Neighborhood Hits	73	Shared Neighborhood Hits	63
SwissProt Accessions	P46460	Gene names	Nsf, Skd2
Domain Architecture
Description	Vesicle-fusing ATPase (EC 3.6.4.6) (Vesicular-fusion protein NSF) (N- ethylmaleimide sensitive fusion protein) (NEM-sensitive fusion protein) (SKD2 protein).

NSF_HUMAN
NC score	0.924363 (rank : 31)	θ value	5.584e-34 (rank : 33)
Query Neighborhood Hits	84	Target Neighborhood Hits	74	Shared Neighborhood Hits	66
SwissProt Accessions	P46459, Q9UKZ2	Gene names	NSF
Domain Architecture
Description	Vesicle-fusing ATPase (EC 3.6.4.6) (Vesicular-fusion protein NSF) (N- ethylmaleimide sensitive fusion protein) (NEM-sensitive fusion protein).

KTNA1_HUMAN
NC score	0.923488 (rank : 32)	θ value	1.51715e-39 (rank : 26)
Query Neighborhood Hits	84	Target Neighborhood Hits	117	Shared Neighborhood Hits	64
SwissProt Accessions	O75449, Q5TFA8, Q5TFA9, Q86VN2, Q9NU52	Gene names	KATNA1
Domain Architecture	No domain graphic available
Description	Katanin p60 ATPase-containing subunit A1 (EC 3.6.4.3) (Katanin p60 subunit A1) (p60 katanin).

KTNA1_MOUSE
NC score	0.921292 (rank : 33)	θ value	1.98146e-39 (rank : 27)
Query Neighborhood Hits	84	Target Neighborhood Hits	123	Shared Neighborhood Hits	64
SwissProt Accessions	Q9WV86	Gene names	Katna1
Domain Architecture	No domain graphic available
Description	Katanin p60 ATPase-containing subunit A1 (EC 3.6.4.3) (Katanin p60 subunit A1) (p60 katanin) (Lipotransin).

SPAST_HUMAN
NC score	0.917842 (rank : 34)	θ value	7.29293e-34 (rank : 34)
Query Neighborhood Hits	84	Target Neighborhood Hits	100	Shared Neighborhood Hits	61
SwissProt Accessions	Q9UBP0, Q9UPR9	Gene names	SPAST, KIAA1083, SPG4
Domain Architecture
Description	Spastin.

SPAST_MOUSE
NC score	0.916139 (rank : 35)	θ value	2.12192e-33 (rank : 35)
Query Neighborhood Hits	84	Target Neighborhood Hits	138	Shared Neighborhood Hits	62
SwissProt Accessions	Q9QYY8, Q6ZPY6, Q80VE0, Q9CVK0	Gene names	Spast, Kiaa1083, Spg4
Domain Architecture	No domain graphic available
Description	Spastin.

VPS4B_HUMAN
NC score	0.909976 (rank : 36)	θ value	5.22648e-32 (rank : 39)
Query Neighborhood Hits	84	Target Neighborhood Hits	87	Shared Neighborhood Hits	61
SwissProt Accessions	O75351, Q9GZS7	Gene names	VPS4B, SKD1, VPS42
Domain Architecture
Description	Vacuolar protein sorting-associating protein 4B (Protein SKD1).

VPS4B_MOUSE
NC score	0.909757 (rank : 37)	θ value	2.34606e-32 (rank : 38)
Query Neighborhood Hits	84	Target Neighborhood Hits	86	Shared Neighborhood Hits	60
SwissProt Accessions	P46467, Q91W22, Q9R1C9	Gene names	Vps4b, Skd1
Domain Architecture
Description	Vacuolar protein sorting-associating protein 4B (Protein SKD1).

VPS4A_HUMAN
NC score	0.907779 (rank : 38)	θ value	4.72714e-33 (rank : 36)
Query Neighborhood Hits	84	Target Neighborhood Hits	95	Shared Neighborhood Hits	61
SwissProt Accessions	Q9UN37, Q8TF07, Q9UI03, Q9Y582	Gene names	VPS4A, VPS4
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associating protein 4A (SKD2 protein) (hVPS4) (VPS4-1).

VPS4A_MOUSE
NC score	0.907760 (rank : 39)	θ value	4.72714e-33 (rank : 37)
Query Neighborhood Hits	84	Target Neighborhood Hits	94	Shared Neighborhood Hits	61
SwissProt Accessions	Q8VEJ9, Q3TXT2	Gene names	Vps4a
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associating protein 4A.

ATAD2_MOUSE
NC score	0.897974 (rank : 40)	θ value	1.28137e-46 (rank : 19)
Query Neighborhood Hits	84	Target Neighborhood Hits	167	Shared Neighborhood Hits	57
SwissProt Accessions	Q8CDM1	Gene names	Atad2
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 2.

ATAD2_HUMAN
NC score	0.880839 (rank : 41)	θ value	1.51363e-47 (rank : 18)
Query Neighborhood Hits	84	Target Neighborhood Hits	322	Shared Neighborhood Hits	59
SwissProt Accessions	Q6PL18, Q658P2, Q68CQ0, Q6PJV6, Q8N890, Q9UHS5	Gene names	ATAD2
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 2.

FIGN_MOUSE
NC score	0.871587 (rank : 42)	θ value	2.51237e-26 (rank : 42)
Query Neighborhood Hits	84	Target Neighborhood Hits	165	Shared Neighborhood Hits	55
SwissProt Accessions	Q9ERZ6, Q3TPB0, Q3UP57, Q6PCM0	Gene names	Fign
Domain Architecture	No domain graphic available
Description	Fidgetin.

FIGN_HUMAN
NC score	0.866006 (rank : 43)	θ value	7.30988e-26 (rank : 43)
Query Neighborhood Hits	84	Target Neighborhood Hits	176	Shared Neighborhood Hits	55
SwissProt Accessions	Q5HY92, Q9H6M5, Q9NVZ9	Gene names	FIGN
Domain Architecture	No domain graphic available
Description	Fidgetin.

BCS1_HUMAN
NC score	0.723579 (rank : 44)	θ value	3.18553e-13 (rank : 44)
Query Neighborhood Hits	84	Target Neighborhood Hits	61	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Y276, Q7Z2V7	Gene names	BCS1L, BCS1
Domain Architecture
Description	Mitochondrial chaperone BCS1 (BCS1-like protein) (H-BCS1).

BCS1_MOUSE
NC score	0.715340 (rank : 45)	θ value	4.16044e-13 (rank : 45)
Query Neighborhood Hits	84	Target Neighborhood Hits	64	Shared Neighborhood Hits	52
SwissProt Accessions	Q9CZP5	Gene names	Bcs1l
Domain Architecture
Description	Mitochondrial chaperone BCS1 (BCS1-like protein).

TRP13_MOUSE
NC score	0.713040 (rank : 46)	θ value	8.11959e-09 (rank : 46)
Query Neighborhood Hits	84	Target Neighborhood Hits	81	Shared Neighborhood Hits	58
SwissProt Accessions	Q3UA06, Q3UQG6, Q9CWW8	Gene names	Trip13
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 13 (Thyroid hormone receptor interactor 13) (Trip-13).

TRP13_HUMAN
NC score	0.709378 (rank : 47)	θ value	1.80886e-08 (rank : 48)
Query Neighborhood Hits	84	Target Neighborhood Hits	81	Shared Neighborhood Hits	59
SwissProt Accessions	Q15645, O15324	Gene names	TRIP13
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 13 (Thyroid hormone receptor interactor 13) (Trip-13) (Human papillomavirus type 16 E1 protein- binding protein) (HPV16 E1 protein-binding protein) (16E1-BP).

ATD3A_HUMAN
NC score	0.630170 (rank : 48)	θ value	1.53129e-07 (rank : 50)
Query Neighborhood Hits	84	Target Neighborhood Hits	248	Shared Neighborhood Hits	62
SwissProt Accessions	Q9NVI7, Q8N275, Q96A50	Gene names	ATAD3A
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 3A.

ATD3B_HUMAN
NC score	0.620855 (rank : 49)	θ value	1.38499e-08 (rank : 47)
Query Neighborhood Hits	84	Target Neighborhood Hits	340	Shared Neighborhood Hits	63
SwissProt Accessions	Q5T9A4, Q6ZRB5, Q9BUK4, Q9ULE7	Gene names	ATAD3B, KIAA1273
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 3B.

ATAD3_MOUSE
NC score	0.612743 (rank : 50)	θ value	5.26297e-08 (rank : 49)
Query Neighborhood Hits	84	Target Neighborhood Hits	326	Shared Neighborhood Hits	64
SwissProt Accessions	Q925I1, Q3UE74, Q69ZM7, Q8C6C6	Gene names	Atad3, Atad3a, Kiaa1273
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 3 (AAA-ATPase TOB3).

CLPX_HUMAN
NC score	0.444497 (rank : 51)	θ value	0.000786445 (rank : 51)
Query Neighborhood Hits	84	Target Neighborhood Hits	72	Shared Neighborhood Hits	51
SwissProt Accessions	O76031, Q9H4D9	Gene names	CLPX
Domain Architecture
Description	ATP-dependent Clp protease ATP-binding subunit ClpX-like, mitochondrial precursor.

CLPX_MOUSE
NC score	0.442680 (rank : 52)	θ value	0.000786445 (rank : 52)
Query Neighborhood Hits	84	Target Neighborhood Hits	73	Shared Neighborhood Hits	51
SwissProt Accessions	Q9JHS4, Q9WVD1	Gene names	Clpx
Domain Architecture
Description	ATP-dependent Clp protease ATP-binding subunit ClpX-like, mitochondrial precursor.

LONM_HUMAN
NC score	0.435324 (rank : 53)	θ value	0.0193708 (rank : 54)
Query Neighborhood Hits	84	Target Neighborhood Hits	130	Shared Neighborhood Hits	59
SwissProt Accessions	P36776, P36777, Q9UQ95	Gene names	PRSS15
Domain Architecture
Description	Lon protease homolog, mitochondrial precursor (EC 3.4.21.-) (Lon protease-like protein) (LONP) (LONHs).

RUVB1_HUMAN
NC score	0.318976 (rank : 54)	θ value	0.0330416 (rank : 56)
Query Neighborhood Hits	84	Target Neighborhood Hits	78	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Y265, Q9BSX9	Gene names	RUVBL1, NMP238, TIP49, TIP49A
Domain Architecture
Description	RuvB-like 1 (EC 3.6.1.-) (49 kDa TATA box-binding protein-interacting protein) (49 kDa TBP-interacting protein) (TIP49a) (Pontin 52) (Nuclear matrix protein 238) (NMP 238) (54 kDa erythrocyte cytosolic protein) (ECP-54) (TIP60-associated protein 54-alpha) (TAP54-alpha).

RUVB1_MOUSE
NC score	0.318937 (rank : 55)	θ value	0.0330416 (rank : 57)
Query Neighborhood Hits	84	Target Neighborhood Hits	78	Shared Neighborhood Hits	59
SwissProt Accessions	P60122, O35753	Gene names	Ruvbl1, Tip49, Tip49a
Domain Architecture
Description	RuvB-like 1 (EC 3.6.1.-) (49 kDa TATA box-binding protein-interacting protein) (49 kDa TBP-interacting protein) (TIP49a) (Pontin 52) (DNA helicase p50).

WRIP1_MOUSE
NC score	0.262689 (rank : 56)	θ value	0.00665767 (rank : 53)
Query Neighborhood Hits	84	Target Neighborhood Hits	93	Shared Neighborhood Hits	52
SwissProt Accessions	Q91XU0, Q3TCT7, Q6PDF0, Q8BUW5, Q8BWP6, Q8BY55, Q921W3, Q9EQL3	Gene names	Wrnip1, Whip
Domain Architecture	No domain graphic available
Description	ATPase WRNIP1 (Werner helicase-interacting protein 1).

WRIP1_HUMAN
NC score	0.258302 (rank : 57)	θ value	0.0193708 (rank : 55)
Query Neighborhood Hits	84	Target Neighborhood Hits	100	Shared Neighborhood Hits	51
SwissProt Accessions	Q96S55, Q53EP6, Q59ET8, Q5W0E2, Q5W0E4, Q8WV26, Q9H681, Q9NRJ6	Gene names	WRNIP1, WHIP
Domain Architecture	No domain graphic available
Description	ATPase WRNIP1 (Werner helicase-interacting protein 1).

RUVB2_HUMAN
NC score	0.122403 (rank : 58)	θ value	5.27518 (rank : 75)
Query Neighborhood Hits	84	Target Neighborhood Hits	43	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Y230, Q6PK27, Q9Y361	Gene names	RUVBL2, TIP48, TIP49B
Domain Architecture
Description	RuvB-like 2 (EC 3.6.1.-) (48 kDa TATA box-binding protein-interacting protein) (48 kDa TBP-interacting protein) (TIP49b) (Repressing pontin 52) (Reptin 52) (51 kDa erythrocyte cytosolic protein) (ECP-51) (TIP60-associated protein 54-beta) (TAP54-beta).

RUVB2_MOUSE
NC score	0.119852 (rank : 59)	θ value	5.27518 (rank : 76)
Query Neighborhood Hits	84	Target Neighborhood Hits	42	Shared Neighborhood Hits	38
SwissProt Accessions	Q9WTM5	Gene names	Ruvbl2
Domain Architecture
Description	RuvB-like 2 (EC 3.6.1.-) (p47 protein).

RFC1_MOUSE
NC score	0.114273 (rank : 60)	θ value	8.99809 (rank : 83)
Query Neighborhood Hits	84	Target Neighborhood Hits	290	Shared Neighborhood Hits	46
SwissProt Accessions	P35601	Gene names	Rfc1, Ibf-1, Recc1
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (A1-P145) (Differentiation- specific element-binding protein) (ISRE-binding protein).

THNSL_MOUSE
NC score	0.106712 (rank : 61)	θ value	8.99809 (rank : 84)
Query Neighborhood Hits	84	Target Neighborhood Hits	47	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BH55	Gene names	Thnsl1
Domain Architecture	No domain graphic available
Description	Threonine synthase-like 1.

THNSL_HUMAN
NC score	0.104392 (rank : 62)	θ value	6.88961 (rank : 79)
Query Neighborhood Hits	84	Target Neighborhood Hits	47	Shared Neighborhood Hits	36
SwissProt Accessions	Q8IYQ7, Q5VV21	Gene names	THNSL1
Domain Architecture	No domain graphic available
Description	Threonine synthase-like 1.

RFC1_HUMAN
NC score	0.101199 (rank : 63)	θ value	8.99809 (rank : 82)
Query Neighborhood Hits	84	Target Neighborhood Hits	352	Shared Neighborhood Hits	45
SwissProt Accessions	P35251, Q5XKF5, Q6PKU0, Q86V41, Q86V46	Gene names	RFC1, RFC140
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (DNA-binding protein PO-GA).

RFC4_HUMAN
NC score	0.101004 (rank : 64)	θ value	θ > 10 (rank : 86)
Query Neighborhood Hits	84	Target Neighborhood Hits	64	Shared Neighborhood Hits	40
SwissProt Accessions	P35249, Q6FHX7	Gene names	RFC4
Domain Architecture
Description	Replication factor C subunit 4 (Replication factor C 37 kDa subunit) (RF-C 37 kDa subunit) (RFC37) (Activator 1 37 kDa subunit) (A1 37 kDa subunit).

KAD6_HUMAN
NC score	0.093553 (rank : 65)	θ value	8.99809 (rank : 80)
Query Neighborhood Hits	84	Target Neighborhood Hits	46	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Y3D8	Gene names	AK6
Domain Architecture
Description	Adenylate kinase isoenzyme 6 (EC 2.7.4.3) (ATP-AMP transphosphorylase 6).

RFC4_MOUSE
NC score	0.089972 (rank : 66)	θ value	θ > 10 (rank : 87)
Query Neighborhood Hits	84	Target Neighborhood Hits	65	Shared Neighborhood Hits	40
SwissProt Accessions	Q99J62	Gene names	Rfc4
Domain Architecture	No domain graphic available
Description	Replication factor C subunit 4.

RFC5_MOUSE
NC score	0.079422 (rank : 67)	θ value	1.06291 (rank : 61)
Query Neighborhood Hits	84	Target Neighborhood Hits	58	Shared Neighborhood Hits	32
SwissProt Accessions	Q9D0F6	Gene names	Rfc5
Domain Architecture
Description	Replication factor C subunit 5 (Replication factor C 36 kDa subunit) (RF-C 36 kDa subunit) (RFC36) (Activator 1 36 kDa subunit) (A1 36 kDa subunit).

RFC5_HUMAN
NC score	0.078006 (rank : 68)	θ value	1.06291 (rank : 60)
Query Neighborhood Hits	84	Target Neighborhood Hits	60	Shared Neighborhood Hits	30
SwissProt Accessions	P40937	Gene names	RFC5
Domain Architecture
Description	Replication factor C subunit 5 (Replication factor C 36 kDa subunit) (RF-C 36 kDa subunit) (RFC36) (Activator 1 36 kDa subunit) (A1 36 kDa subunit).

KAD6_MOUSE
NC score	0.071031 (rank : 69)	θ value	θ > 10 (rank : 85)
Query Neighborhood Hits	84	Target Neighborhood Hits	34	Shared Neighborhood Hits	22
SwissProt Accessions	Q8VCP8	Gene names	Ak6
Domain Architecture	No domain graphic available
Description	Adenylate kinase isoenzyme 6 (EC 2.7.4.3) (ATP-AMP transphosphorylase 6).

MDN1_HUMAN
NC score	0.038758 (rank : 70)	θ value	4.03905 (rank : 69)
Query Neighborhood Hits	84	Target Neighborhood Hits	662	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

KAD2_HUMAN
NC score	0.037280 (rank : 71)	θ value	0.163984 (rank : 58)
Query Neighborhood Hits	84	Target Neighborhood Hits	23	Shared Neighborhood Hits	6
SwissProt Accessions	P54819, Q16856, Q5TIF7, Q8TCY2, Q8TCY3	Gene names	AK2, ADK2
Domain Architecture
Description	Adenylate kinase isoenzyme 2, mitochondrial (EC 2.7.4.3) (ATP-AMP transphosphorylase).

RENT1_MOUSE
NC score	0.026915 (rank : 72)	θ value	4.03905 (rank : 70)
Query Neighborhood Hits	84	Target Neighborhood Hits	54	Shared Neighborhood Hits	9
SwissProt Accessions	Q9EPU0, Q99PR4	Gene names	Upf1, Rent1
Domain Architecture
Description	Regulator of nonsense transcripts 1 (EC 3.6.1.-) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up- frameshift suppressor 1 homolog) (mUpf1).

RENT1_HUMAN
NC score	0.025380 (rank : 73)	θ value	5.27518 (rank : 74)
Query Neighborhood Hits	84	Target Neighborhood Hits	51	Shared Neighborhood Hits	9
SwissProt Accessions	Q92900, O00239, O43343, Q86Z25, Q92842	Gene names	UPF1, KIAA0221, RENT1
Domain Architecture
Description	Regulator of nonsense transcripts 1 (EC 3.6.1.-) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up- frameshift suppressor 1 homolog) (hUpf1).

CKAP5_HUMAN
NC score	0.023277 (rank : 74)	θ value	1.38821 (rank : 62)
Query Neighborhood Hits	84	Target Neighborhood Hits	96	Shared Neighborhood Hits	3
SwissProt Accessions	Q14008, Q14668	Gene names	CKAP5, KIAA0097
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 5 (Colonic and hepatic tumor over- expressed protein) (Ch-TOG protein).

ICA69_HUMAN
NC score	0.022340 (rank : 75)	θ value	0.47712 (rank : 59)
Query Neighborhood Hits	84	Target Neighborhood Hits	35	Shared Neighborhood Hits	5
SwissProt Accessions	Q05084, P78506, Q13824	Gene names	ICA1
Domain Architecture
Description	Islet cell autoantigen 1 (69 kDa islet cell autoantigen) (ICA69) (p69) (Islet cell autoantigen p69) (ICAp69).

KAD2_MOUSE
NC score	0.018633 (rank : 76)	θ value	6.88961 (rank : 77)
Query Neighborhood Hits	84	Target Neighborhood Hits	21	Shared Neighborhood Hits	6
SwissProt Accessions	Q9WTP6, Q3TKI6, Q9CY37	Gene names	Ak2, Ak-2
Domain Architecture
Description	Adenylate kinase isoenzyme 2, mitochondrial (EC 2.7.4.3) (ATP-AMP transphosphorylase).

LC7L2_HUMAN
NC score	0.013786 (rank : 77)	θ value	2.36792 (rank : 63)
Query Neighborhood Hits	84	Target Neighborhood Hits	235	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y383, Q8IUP9, Q9NVL3, Q9NVN7, Q9UQN1	Gene names	LUC7L2
Domain Architecture
Description	Putative RNA-binding protein Luc7-like 2.

LC7L2_MOUSE
NC score	0.013591 (rank : 78)	θ value	2.36792 (rank : 64)
Query Neighborhood Hits	84	Target Neighborhood Hits	244	Shared Neighborhood Hits	5
SwissProt Accessions	Q7TNC4, Q99LM5, Q99PC3	Gene names	Luc7l2
Domain Architecture
Description	Putative RNA-binding protein Luc7-like 2 (CGI-74 homolog).

IF140_HUMAN
NC score	0.012195 (rank : 79)	θ value	5.27518 (rank : 72)
Query Neighborhood Hits	84	Target Neighborhood Hits	111	Shared Neighborhood Hits	3
SwissProt Accessions	Q96RY7, O60332	Gene names	IFT140, KIAA0590, WDTC2
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 140 homolog (WD and tetratricopeptide repeats protein 2).

CDC27_HUMAN
NC score	0.011458 (rank : 80)	θ value	3.0926 (rank : 67)
Query Neighborhood Hits	84	Target Neighborhood Hits	139	Shared Neighborhood Hits	3
SwissProt Accessions	P30260, Q16349, Q96F35	Gene names	CDC27
Domain Architecture
Description	Cell division cycle protein 27 homolog (CDC27Hs) (H-NUC).

NCOA7_HUMAN
NC score	0.010810 (rank : 81)	θ value	3.0926 (rank : 68)
Query Neighborhood Hits	84	Target Neighborhood Hits	160	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NI08, Q3LID6, Q4G0V1, Q5TF95, Q6IPQ4, Q6NE83, Q86T89, Q8N1W4	Gene names	NCOA7, ERAP140, ESNA1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 7 (140 kDa estrogen receptor-associated protein) (Estrogen nuclear receptor coactivator 1).

SIN3A_MOUSE
NC score	0.010465 (rank : 82)	θ value	2.36792 (rank : 66)
Query Neighborhood Hits	84	Target Neighborhood Hits	169	Shared Neighborhood Hits	3
SwissProt Accessions	Q60520, Q60820, Q62139, Q62140, Q7TPU8, Q7TSZ2	Gene names	Sin3a
Domain Architecture
Description	Paired amphipathic helix protein Sin3a (Transcriptional corepressor Sin3a) (Histone deacetylase complex subunit Sin3a).

PALM_MOUSE
NC score	0.009454 (rank : 83)	θ value	5.27518 (rank : 73)
Query Neighborhood Hits	84	Target Neighborhood Hits	228	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z0P4, Q9Z0P3	Gene names	Palm
Domain Architecture
Description	Paralemmin.

CCD91_HUMAN
NC score	0.001860 (rank : 84)	θ value	5.27518 (rank : 71)
Query Neighborhood Hits	84	Target Neighborhood Hits	868	Shared Neighborhood Hits	9
SwissProt Accessions	Q7Z6B0, Q68D43, Q6IA78, Q8NEN7, Q9NUW9	Gene names	CCDC91, GGABP
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner) (p56 accessory protein).

LRC45_HUMAN
NC score	0.001797 (rank : 85)	θ value	2.36792 (rank : 65)
Query Neighborhood Hits	84	Target Neighborhood Hits	933	Shared Neighborhood Hits	9
SwissProt Accessions	Q96CN5	Gene names	LRRC45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

P55G_HUMAN
NC score	0.000590 (rank : 86)	θ value	8.99809 (rank : 81)
Query Neighborhood Hits	84	Target Neighborhood Hits	451	Shared Neighborhood Hits	4
SwissProt Accessions	Q92569, O60482	Gene names	PIK3R3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

SYNE2_HUMAN
NC score	-0.001374 (rank : 87)	θ value	6.88961 (rank : 78)
Query Neighborhood Hits	84	Target Neighborhood Hits	1323	Shared Neighborhood Hits	12
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).