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Network neighborhood for query Sequence : PEX1_HUMAN

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PEX1_HUMAN
SwissProt Accessions	O43933, Q96S71, Q96S72, Q96S73, Q99994	Gene names	PEX1
Domain Architecture
Description	Peroxisome biogenesis factor 1 (Peroxin-1) (Peroxisome biogenesis disorder protein 1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PEX1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	98	Target Neighborhood Hits	98	Shared Neighborhood Hits	98
SwissProt Accessions	O43933, Q96S71, Q96S72, Q96S73, Q99994	Gene names	PEX1
Domain Architecture
Description	Peroxisome biogenesis factor 1 (Peroxin-1) (Peroxisome biogenesis disorder protein 1).

TERA_HUMAN
θ value	3.70236e-70 (rank : 2)	NC score	0.965472 (rank : 2)
Query Neighborhood Hits	98	Target Neighborhood Hits	76	Shared Neighborhood Hits	63
SwissProt Accessions	P55072, Q969G7	Gene names	VCP
Domain Architecture
Description	Transitional endoplasmic reticulum ATPase (TER ATPase) (15S Mg(2+)- ATPase p97 subunit) (Valosin-containing protein) (VCP).

TERA_MOUSE
θ value	3.70236e-70 (rank : 3)	NC score	0.965464 (rank : 3)
Query Neighborhood Hits	98	Target Neighborhood Hits	76	Shared Neighborhood Hits	63
SwissProt Accessions	Q01853	Gene names	Vcp
Domain Architecture
Description	Transitional endoplasmic reticulum ATPase (TER ATPase) (15S Mg(2+)- ATPase p97 subunit) (Valosin-containing protein) (VCP).

PEX6_MOUSE
θ value	3.03575e-64 (rank : 4)	NC score	0.956028 (rank : 6)
Query Neighborhood Hits	98	Target Neighborhood Hits	94	Shared Neighborhood Hits	63
SwissProt Accessions	Q99LC9, Q6YNQ9	Gene names	Pex6
Domain Architecture	No domain graphic available
Description	Peroxisome assembly factor 2 (PAF-2) (Peroxisomal-type ATPase 1) (Peroxin-6) (Peroxisomal biogenesis factor 6).

PEX6_HUMAN
θ value	2.56992e-63 (rank : 5)	NC score	0.956027 (rank : 7)
Query Neighborhood Hits	98	Target Neighborhood Hits	99	Shared Neighborhood Hits	64
SwissProt Accessions	Q13608, Q8WYQ2, Q99476	Gene names	PEX6, PXAAA1
Domain Architecture
Description	Peroxisome assembly factor 2 (PAF-2) (Peroxisomal-type ATPase 1) (Peroxin-6) (Peroxisomal biogenesis factor 6).

NVL_MOUSE
θ value	3.14151e-61 (rank : 6)	NC score	0.957942 (rank : 4)
Query Neighborhood Hits	98	Target Neighborhood Hits	110	Shared Neighborhood Hits	64
SwissProt Accessions	Q9DBY8, Q3USC4, Q8BW27, Q8K2B5	Gene names	Nvl
Domain Architecture
Description	Nuclear valosin-containing protein-like (Nuclear VCP-like protein) (NVLp).

NVL_HUMAN
θ value	4.10295e-61 (rank : 7)	NC score	0.957210 (rank : 5)
Query Neighborhood Hits	98	Target Neighborhood Hits	112	Shared Neighborhood Hits	64
SwissProt Accessions	O15381, Q96EM7	Gene names	NVL
Domain Architecture
Description	Nuclear valosin-containing protein-like (Nuclear VCP-like protein) (NVLp).

PRS10_HUMAN
θ value	5.38352e-45 (rank : 8)	NC score	0.950720 (rank : 8)
Query Neighborhood Hits	98	Target Neighborhood Hits	95	Shared Neighborhood Hits	62
SwissProt Accessions	P62333, P49719, Q6IBU3, Q92524	Gene names	PSMC6, SUG2
Domain Architecture
Description	26S protease regulatory subunit S10B (Proteasome subunit p42) (Proteasome 26S subunit ATPase 6).

PRS10_MOUSE
θ value	5.38352e-45 (rank : 9)	NC score	0.950720 (rank : 9)
Query Neighborhood Hits	98	Target Neighborhood Hits	95	Shared Neighborhood Hits	62
SwissProt Accessions	P62334, P49719, Q3TKK1, Q810A6, Q92524, Q9CXH9	Gene names	Psmc6, Sug2
Domain Architecture
Description	26S protease regulatory subunit S10B (Proteasome subunit p42) (Proteasome 26S subunit ATPase 6).

PRS8_HUMAN
θ value	2.04573e-44 (rank : 10)	NC score	0.949876 (rank : 10)
Query Neighborhood Hits	98	Target Neighborhood Hits	117	Shared Neighborhood Hits	62
SwissProt Accessions	P62195, O35051, O43208, P47210, P52915, P52916	Gene names	PSMC5, SUG1
Domain Architecture
Description	26S protease regulatory subunit 8 (Proteasome 26S subunit ATPase 5) (Proteasome subunit p45) (p45/SUG) (Thyroid hormone receptor- interacting protein 1) (TRIP1).

PRS8_MOUSE
θ value	2.04573e-44 (rank : 11)	NC score	0.949876 (rank : 11)
Query Neighborhood Hits	98	Target Neighborhood Hits	117	Shared Neighborhood Hits	62
SwissProt Accessions	P62196, O35051, P47210, P52915, P52916, Q3UL51, Q9CWN5	Gene names	Psmc5, Sug1
Domain Architecture
Description	26S protease regulatory subunit 8 (Proteasome 26S subunit ATPase 5) (Proteasome subunit p45) (p45/SUG) (mSUG1).

PRS4_HUMAN
θ value	9.50281e-42 (rank : 12)	NC score	0.948081 (rank : 12)
Query Neighborhood Hits	98	Target Neighborhood Hits	84	Shared Neighborhood Hits	63
SwissProt Accessions	P62191, P49014, Q03527, Q6IAW0, Q96AZ3	Gene names	PSMC1
Domain Architecture
Description	26S protease regulatory subunit 4 (P26s4) (Proteasome 26S subunit ATPase 1).

PRS4_MOUSE
θ value	9.50281e-42 (rank : 13)	NC score	0.948081 (rank : 13)
Query Neighborhood Hits	98	Target Neighborhood Hits	84	Shared Neighborhood Hits	63
SwissProt Accessions	P62192, P49014, Q03527, Q96AZ3	Gene names	Psmc1
Domain Architecture
Description	26S protease regulatory subunit 4 (P26s4) (Proteasome 26S subunit ATPase 1).

PRS6A_HUMAN
θ value	1.3722e-40 (rank : 14)	NC score	0.945598 (rank : 17)
Query Neighborhood Hits	98	Target Neighborhood Hits	87	Shared Neighborhood Hits	61
SwissProt Accessions	P17980, Q96HD3	Gene names	PSMC3, TBP1
Domain Architecture
Description	26S protease regulatory subunit 6A (Proteasome 26S subunit ATPase 3) (TAT-binding protein 1) (TBP-1) (Proteasome subunit P50).

PRS6A_MOUSE
θ value	1.79215e-40 (rank : 15)	NC score	0.945782 (rank : 16)
Query Neighborhood Hits	98	Target Neighborhood Hits	85	Shared Neighborhood Hits	61
SwissProt Accessions	O88685	Gene names	Psmc3, Tbp1
Domain Architecture
Description	26S protease regulatory subunit 6A (Proteasome 26S subunit ATPase 3) (TAT-binding protein 1) (TBP-1).

PRS7_HUMAN
θ value	5.76516e-39 (rank : 16)	NC score	0.946020 (rank : 14)
Query Neighborhood Hits	98	Target Neighborhood Hits	66	Shared Neighborhood Hits	57
SwissProt Accessions	P35998	Gene names	PSMC2, MSS1
Domain Architecture
Description	26S protease regulatory subunit 7 (Proteasome 26S subunit ATPase 2) (Protein MSS1).

PRS7_MOUSE
θ value	5.76516e-39 (rank : 17)	NC score	0.946010 (rank : 15)
Query Neighborhood Hits	98	Target Neighborhood Hits	67	Shared Neighborhood Hits	57
SwissProt Accessions	P46471, O08531, Q3TGX5, Q9DBA1	Gene names	Psmc2, Mss1
Domain Architecture
Description	26S protease regulatory subunit 7 (Proteasome 26S subunit ATPase 2) (Protein MSS1).

PRS6B_HUMAN
θ value	2.19075e-38 (rank : 18)	NC score	0.943867 (rank : 18)
Query Neighborhood Hits	98	Target Neighborhood Hits	85	Shared Neighborhood Hits	57
SwissProt Accessions	P43686, Q96FV5, Q9UBM3, Q9UEX3	Gene names	PSMC4, TBP7
Domain Architecture
Description	26S protease regulatory subunit 6B (Proteasome 26S subunit ATPase 4) (MIP224) (MB67-interacting protein) (TAT-binding protein 7) (TBP-7).

PRS6B_MOUSE
θ value	2.86122e-38 (rank : 19)	NC score	0.943476 (rank : 19)
Query Neighborhood Hits	98	Target Neighborhood Hits	89	Shared Neighborhood Hits	57
SwissProt Accessions	P54775	Gene names	Psmc4, Tbp7
Domain Architecture
Description	26S protease regulatory subunit 6B (Proteasome 26S subunit ATPase 4) (MIP224) (MB67-interacting protein) (TAT-binding protein 7) (TBP-7) (CIP21).

AFG32_HUMAN
θ value	7.04741e-37 (rank : 20)	NC score	0.924369 (rank : 26)
Query Neighborhood Hits	98	Target Neighborhood Hits	72	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Y4W6	Gene names	AFG3L2
Domain Architecture
Description	AFG3-like protein 2 (EC 3.4.24.-) (Paraplegin-like protein).

AFG32_MOUSE
θ value	7.04741e-37 (rank : 21)	NC score	0.924055 (rank : 28)
Query Neighborhood Hits	98	Target Neighborhood Hits	73	Shared Neighborhood Hits	60
SwissProt Accessions	Q8JZQ2	Gene names	Afg3l2
Domain Architecture	No domain graphic available
Description	AFG3-like protein 2 (EC 3.4.24.-).

AFG31_MOUSE
θ value	1.20211e-36 (rank : 22)	NC score	0.928290 (rank : 22)
Query Neighborhood Hits	98	Target Neighborhood Hits	74	Shared Neighborhood Hits	60
SwissProt Accessions	Q920A7	Gene names	Afg3l1
Domain Architecture
Description	AFG3-like protein 1 (EC 3.4.24.-).

ATAD2_MOUSE
θ value	7.79185e-36 (rank : 23)	NC score	0.886312 (rank : 40)
Query Neighborhood Hits	98	Target Neighborhood Hits	167	Shared Neighborhood Hits	59
SwissProt Accessions	Q8CDM1	Gene names	Atad2
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 2.

NSF_MOUSE
θ value	1.01765e-35 (rank : 24)	NC score	0.924346 (rank : 27)
Query Neighborhood Hits	98	Target Neighborhood Hits	73	Shared Neighborhood Hits	59
SwissProt Accessions	P46460	Gene names	Nsf, Skd2
Domain Architecture
Description	Vesicle-fusing ATPase (EC 3.6.4.6) (Vesicular-fusion protein NSF) (N- ethylmaleimide sensitive fusion protein) (NEM-sensitive fusion protein) (SKD2 protein).

ATAD2_HUMAN
θ value	1.32909e-35 (rank : 25)	NC score	0.868636 (rank : 41)
Query Neighborhood Hits	98	Target Neighborhood Hits	322	Shared Neighborhood Hits	63
SwissProt Accessions	Q6PL18, Q658P2, Q68CQ0, Q6PJV6, Q8N890, Q9UHS5	Gene names	ATAD2
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 2.

KTNA1_HUMAN
θ value	2.96089e-35 (rank : 26)	NC score	0.922484 (rank : 30)
Query Neighborhood Hits	98	Target Neighborhood Hits	117	Shared Neighborhood Hits	62
SwissProt Accessions	O75449, Q5TFA8, Q5TFA9, Q86VN2, Q9NU52	Gene names	KATNA1
Domain Architecture	No domain graphic available
Description	Katanin p60 ATPase-containing subunit A1 (EC 3.6.4.3) (Katanin p60 subunit A1) (p60 katanin).

NSF_HUMAN
θ value	2.96089e-35 (rank : 27)	NC score	0.924029 (rank : 29)
Query Neighborhood Hits	98	Target Neighborhood Hits	74	Shared Neighborhood Hits	60
SwissProt Accessions	P46459, Q9UKZ2	Gene names	NSF
Domain Architecture
Description	Vesicle-fusing ATPase (EC 3.6.4.6) (Vesicular-fusion protein NSF) (N- ethylmaleimide sensitive fusion protein) (NEM-sensitive fusion protein).

KATL1_MOUSE
θ value	4.27553e-34 (rank : 28)	NC score	0.925127 (rank : 24)
Query Neighborhood Hits	98	Target Neighborhood Hits	77	Shared Neighborhood Hits	62
SwissProt Accessions	Q8K0T4	Gene names	Katnal1
Domain Architecture	No domain graphic available
Description	Katanin p60 ATPase-containing subunit A-like 1 (EC 3.6.4.3) (Katanin p60 subunit A-like 1) (p60 katanin-like 1).

YMEL1_HUMAN
θ value	9.52487e-34 (rank : 29)	NC score	0.919111 (rank : 33)
Query Neighborhood Hits	98	Target Neighborhood Hits	73	Shared Neighborhood Hits	57
SwissProt Accessions	Q96TA2, Q9H1Q0, Q9UMR9	Gene names	YME1L1, FTSH1, YME1L
Domain Architecture
Description	ATP-dependent metalloprotease YME1L1 (EC 3.4.24.-) (YME1-like protein 1) (ATP-dependent metalloprotease FtsH1) (Meg-4) (Presenilin- associated metalloprotease) (PAMP).

YMEL1_MOUSE
θ value	1.24399e-33 (rank : 30)	NC score	0.922382 (rank : 31)
Query Neighborhood Hits	98	Target Neighborhood Hits	76	Shared Neighborhood Hits	57
SwissProt Accessions	O88967, Q7TNN5	Gene names	Yme1l1
Domain Architecture
Description	ATP-dependent metalloprotease YME1L1 (EC 3.4.24.-) (YME1-like protein 1) (ATP-dependent metalloprotease FtsH1).

KTNA1_MOUSE
θ value	2.12192e-33 (rank : 31)	NC score	0.919690 (rank : 32)
Query Neighborhood Hits	98	Target Neighborhood Hits	123	Shared Neighborhood Hits	62
SwissProt Accessions	Q9WV86	Gene names	Katna1
Domain Architecture	No domain graphic available
Description	Katanin p60 ATPase-containing subunit A1 (EC 3.6.4.3) (Katanin p60 subunit A1) (p60 katanin) (Lipotransin).

KATL1_HUMAN
θ value	2.77131e-33 (rank : 32)	NC score	0.924730 (rank : 25)
Query Neighborhood Hits	98	Target Neighborhood Hits	80	Shared Neighborhood Hits	62
SwissProt Accessions	Q9BW62	Gene names	KATNAL1
Domain Architecture	No domain graphic available
Description	Katanin p60 ATPase-containing subunit A-like 1 (EC 3.6.4.3) (Katanin p60 subunit A-like 1) (p60 katanin-like 1).

SPG7_HUMAN
θ value	3.06405e-32 (rank : 33)	NC score	0.926367 (rank : 23)
Query Neighborhood Hits	98	Target Neighborhood Hits	71	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UQ90, O75756, Q96IB0	Gene names	SPG7, CAR, CMAR, PGN
Domain Architecture
Description	Paraplegin (EC 3.4.24.-) (Spastic paraplegia protein 7).

VPS4A_HUMAN
θ value	2.59387e-31 (rank : 34)	NC score	0.909205 (rank : 38)
Query Neighborhood Hits	98	Target Neighborhood Hits	95	Shared Neighborhood Hits	61
SwissProt Accessions	Q9UN37, Q8TF07, Q9UI03, Q9Y582	Gene names	VPS4A, VPS4
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associating protein 4A (SKD2 protein) (hVPS4) (VPS4-1).

VPS4A_MOUSE
θ value	2.59387e-31 (rank : 35)	NC score	0.909196 (rank : 39)
Query Neighborhood Hits	98	Target Neighborhood Hits	94	Shared Neighborhood Hits	61
SwissProt Accessions	Q8VEJ9, Q3TXT2	Gene names	Vps4a
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associating protein 4A.

SPAST_MOUSE
θ value	4.42448e-31 (rank : 36)	NC score	0.914109 (rank : 35)
Query Neighborhood Hits	98	Target Neighborhood Hits	138	Shared Neighborhood Hits	60
SwissProt Accessions	Q9QYY8, Q6ZPY6, Q80VE0, Q9CVK0	Gene names	Spast, Kiaa1083, Spg4
Domain Architecture	No domain graphic available
Description	Spastin.

SPAST_HUMAN
θ value	7.54701e-31 (rank : 37)	NC score	0.915206 (rank : 34)
Query Neighborhood Hits	98	Target Neighborhood Hits	100	Shared Neighborhood Hits	60
SwissProt Accessions	Q9UBP0, Q9UPR9	Gene names	SPAST, KIAA1083, SPG4
Domain Architecture
Description	Spastin.

VPS4B_MOUSE
θ value	4.89182e-30 (rank : 38)	NC score	0.909743 (rank : 37)
Query Neighborhood Hits	98	Target Neighborhood Hits	86	Shared Neighborhood Hits	60
SwissProt Accessions	P46467, Q91W22, Q9R1C9	Gene names	Vps4b, Skd1
Domain Architecture
Description	Vacuolar protein sorting-associating protein 4B (Protein SKD1).

VPS4B_HUMAN
θ value	1.85889e-29 (rank : 39)	NC score	0.910165 (rank : 36)
Query Neighborhood Hits	98	Target Neighborhood Hits	87	Shared Neighborhood Hits	61
SwissProt Accessions	O75351, Q9GZS7	Gene names	VPS4B, SKD1, VPS42
Domain Architecture
Description	Vacuolar protein sorting-associating protein 4B (Protein SKD1).

ATAD1_HUMAN
θ value	3.28125e-26 (rank : 40)	NC score	0.928341 (rank : 20)
Query Neighborhood Hits	98	Target Neighborhood Hits	75	Shared Neighborhood Hits	60
SwissProt Accessions	Q8NBU5, Q6P4B9, Q8N3G1, Q8WYR9, Q969Y3	Gene names	ATAD1
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 1.

ATAD1_MOUSE
θ value	3.28125e-26 (rank : 41)	NC score	0.928341 (rank : 21)
Query Neighborhood Hits	98	Target Neighborhood Hits	75	Shared Neighborhood Hits	60
SwissProt Accessions	Q9D5T0, Q3U8V2, Q9D7A4	Gene names	Atad1
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 1.

FIGN_HUMAN
θ value	2.43343e-21 (rank : 42)	NC score	0.861156 (rank : 43)
Query Neighborhood Hits	98	Target Neighborhood Hits	176	Shared Neighborhood Hits	55
SwissProt Accessions	Q5HY92, Q9H6M5, Q9NVZ9	Gene names	FIGN
Domain Architecture	No domain graphic available
Description	Fidgetin.

FIGN_MOUSE
θ value	5.42112e-21 (rank : 43)	NC score	0.866079 (rank : 42)
Query Neighborhood Hits	98	Target Neighborhood Hits	165	Shared Neighborhood Hits	54
SwissProt Accessions	Q9ERZ6, Q3TPB0, Q3UP57, Q6PCM0	Gene names	Fign
Domain Architecture	No domain graphic available
Description	Fidgetin.

TRP13_MOUSE
θ value	2.13673e-09 (rank : 44)	NC score	0.725020 (rank : 44)
Query Neighborhood Hits	98	Target Neighborhood Hits	81	Shared Neighborhood Hits	55
SwissProt Accessions	Q3UA06, Q3UQG6, Q9CWW8	Gene names	Trip13
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 13 (Thyroid hormone receptor interactor 13) (Trip-13).

TRP13_HUMAN
θ value	2.79066e-09 (rank : 45)	NC score	0.721824 (rank : 45)
Query Neighborhood Hits	98	Target Neighborhood Hits	81	Shared Neighborhood Hits	55
SwissProt Accessions	Q15645, O15324	Gene names	TRIP13
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 13 (Thyroid hormone receptor interactor 13) (Trip-13) (Human papillomavirus type 16 E1 protein- binding protein) (HPV16 E1 protein-binding protein) (16E1-BP).

ATD3A_HUMAN
θ value	2.88788e-06 (rank : 46)	NC score	0.615996 (rank : 48)
Query Neighborhood Hits	98	Target Neighborhood Hits	248	Shared Neighborhood Hits	63
SwissProt Accessions	Q9NVI7, Q8N275, Q96A50	Gene names	ATAD3A
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 3A.

ATAD3_MOUSE
θ value	3.77169e-06 (rank : 47)	NC score	0.598061 (rank : 50)
Query Neighborhood Hits	98	Target Neighborhood Hits	326	Shared Neighborhood Hits	62
SwissProt Accessions	Q925I1, Q3UE74, Q69ZM7, Q8C6C6	Gene names	Atad3, Atad3a, Kiaa1273
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 3 (AAA-ATPase TOB3).

ATD3B_HUMAN
θ value	4.92598e-06 (rank : 48)	NC score	0.605094 (rank : 49)
Query Neighborhood Hits	98	Target Neighborhood Hits	340	Shared Neighborhood Hits	60
SwissProt Accessions	Q5T9A4, Q6ZRB5, Q9BUK4, Q9ULE7	Gene names	ATAD3B, KIAA1273
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 3B.

BCS1_HUMAN
θ value	4.92598e-06 (rank : 49)	NC score	0.677290 (rank : 46)
Query Neighborhood Hits	98	Target Neighborhood Hits	61	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Y276, Q7Z2V7	Gene names	BCS1L, BCS1
Domain Architecture
Description	Mitochondrial chaperone BCS1 (BCS1-like protein) (H-BCS1).

BCS1_MOUSE
θ value	1.43324e-05 (rank : 50)	NC score	0.665702 (rank : 47)
Query Neighborhood Hits	98	Target Neighborhood Hits	64	Shared Neighborhood Hits	52
SwissProt Accessions	Q9CZP5	Gene names	Bcs1l
Domain Architecture
Description	Mitochondrial chaperone BCS1 (BCS1-like protein).

RUVB1_HUMAN
θ value	0.0148317 (rank : 51)	NC score	0.324012 (rank : 54)
Query Neighborhood Hits	98	Target Neighborhood Hits	78	Shared Neighborhood Hits	57
SwissProt Accessions	Q9Y265, Q9BSX9	Gene names	RUVBL1, NMP238, TIP49, TIP49A
Domain Architecture
Description	RuvB-like 1 (EC 3.6.1.-) (49 kDa TATA box-binding protein-interacting protein) (49 kDa TBP-interacting protein) (TIP49a) (Pontin 52) (Nuclear matrix protein 238) (NMP 238) (54 kDa erythrocyte cytosolic protein) (ECP-54) (TIP60-associated protein 54-alpha) (TAP54-alpha).

RUVB1_MOUSE
θ value	0.0148317 (rank : 52)	NC score	0.323971 (rank : 55)
Query Neighborhood Hits	98	Target Neighborhood Hits	78	Shared Neighborhood Hits	57
SwissProt Accessions	P60122, O35753	Gene names	Ruvbl1, Tip49, Tip49a
Domain Architecture
Description	RuvB-like 1 (EC 3.6.1.-) (49 kDa TATA box-binding protein-interacting protein) (49 kDa TBP-interacting protein) (TIP49a) (Pontin 52) (DNA helicase p50).

WRIP1_MOUSE
θ value	0.0193708 (rank : 53)	NC score	0.255434 (rank : 56)
Query Neighborhood Hits	98	Target Neighborhood Hits	93	Shared Neighborhood Hits	50
SwissProt Accessions	Q91XU0, Q3TCT7, Q6PDF0, Q8BUW5, Q8BWP6, Q8BY55, Q921W3, Q9EQL3	Gene names	Wrnip1, Whip
Domain Architecture	No domain graphic available
Description	ATPase WRNIP1 (Werner helicase-interacting protein 1).

WRIP1_HUMAN
θ value	0.0252991 (rank : 54)	NC score	0.253479 (rank : 57)
Query Neighborhood Hits	98	Target Neighborhood Hits	100	Shared Neighborhood Hits	50
SwissProt Accessions	Q96S55, Q53EP6, Q59ET8, Q5W0E2, Q5W0E4, Q8WV26, Q9H681, Q9NRJ6	Gene names	WRNIP1, WHIP
Domain Architecture	No domain graphic available
Description	ATPase WRNIP1 (Werner helicase-interacting protein 1).

ALO17_HUMAN
θ value	0.0736092 (rank : 55)	NC score	0.032837 (rank : 77)
Query Neighborhood Hits	98	Target Neighborhood Hits	317	Shared Neighborhood Hits	4
SwissProt Accessions	Q9HCF4, Q69YK7, Q8IWF4, Q8IZX1, Q8IZX2, Q8N406	Gene names	KIAA1618, ALO17
Domain Architecture	No domain graphic available
Description	Protein ALO17 (ALK lymphoma oligomerization partner on chromosome 17).

CLPX_HUMAN
θ value	0.0736092 (rank : 56)	NC score	0.418919 (rank : 51)
Query Neighborhood Hits	98	Target Neighborhood Hits	72	Shared Neighborhood Hits	51
SwissProt Accessions	O76031, Q9H4D9	Gene names	CLPX
Domain Architecture
Description	ATP-dependent Clp protease ATP-binding subunit ClpX-like, mitochondrial precursor.

CLPX_MOUSE
θ value	0.0736092 (rank : 57)	NC score	0.416891 (rank : 52)
Query Neighborhood Hits	98	Target Neighborhood Hits	73	Shared Neighborhood Hits	51
SwissProt Accessions	Q9JHS4, Q9WVD1	Gene names	Clpx
Domain Architecture
Description	ATP-dependent Clp protease ATP-binding subunit ClpX-like, mitochondrial precursor.

DHE3_HUMAN
θ value	0.62314 (rank : 58)	NC score	0.035023 (rank : 71)
Query Neighborhood Hits	98	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	P00367	Gene names	GLUD1, GLUD
Domain Architecture
Description	Glutamate dehydrogenase 1, mitochondrial precursor (EC 1.4.1.3) (GDH).

DHE3_MOUSE
θ value	0.62314 (rank : 59)	NC score	0.034967 (rank : 72)
Query Neighborhood Hits	98	Target Neighborhood Hits	9	Shared Neighborhood Hits	4
SwissProt Accessions	P26443, Q8C273	Gene names	Glud1, Glud
Domain Architecture
Description	Glutamate dehydrogenase 1, mitochondrial precursor (EC 1.4.1.3) (GDH).

DHE4_HUMAN
θ value	0.62314 (rank : 60)	NC score	0.034947 (rank : 73)
Query Neighborhood Hits	98	Target Neighborhood Hits	13	Shared Neighborhood Hits	4
SwissProt Accessions	P49448, Q9UDQ4	Gene names	GLUD2, GLUDP1
Domain Architecture
Description	Glutamate dehydrogenase 2, mitochondrial precursor (EC 1.4.1.3) (GDH).

RENT1_HUMAN
θ value	1.38821 (rank : 61)	NC score	0.033155 (rank : 76)
Query Neighborhood Hits	98	Target Neighborhood Hits	51	Shared Neighborhood Hits	14
SwissProt Accessions	Q92900, O00239, O43343, Q86Z25, Q92842	Gene names	UPF1, KIAA0221, RENT1
Domain Architecture
Description	Regulator of nonsense transcripts 1 (EC 3.6.1.-) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up- frameshift suppressor 1 homolog) (hUpf1).

ATF2_HUMAN
θ value	1.81305 (rank : 62)	NC score	0.012198 (rank : 82)
Query Neighborhood Hits	98	Target Neighborhood Hits	402	Shared Neighborhood Hits	3
SwissProt Accessions	P15336, Q13000	Gene names	ATF2, CREB2, CREBP1
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-2 (Activating transcription factor 2) (cAMP response element-binding protein CRE- BP1) (HB16).

GP156_HUMAN
θ value	1.81305 (rank : 63)	NC score	0.014422 (rank : 80)
Query Neighborhood Hits	98	Target Neighborhood Hits	84	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NFN8, Q86SN6	Gene names	GPR156, GABABL, PGR28
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 156 (GABAB-related G-protein coupled receptor) (G-protein coupled receptor PGR28).

NPAS1_MOUSE
θ value	1.81305 (rank : 64)	NC score	0.007456 (rank : 85)
Query Neighborhood Hits	98	Target Neighborhood Hits	63	Shared Neighborhood Hits	3
SwissProt Accessions	P97459	Gene names	Npas1
Domain Architecture
Description	Neuronal PAS domain-containing protein 1 (Neuronal PAS1).

RENT1_MOUSE
θ value	1.81305 (rank : 65)	NC score	0.033871 (rank : 75)
Query Neighborhood Hits	98	Target Neighborhood Hits	54	Shared Neighborhood Hits	14
SwissProt Accessions	Q9EPU0, Q99PR4	Gene names	Upf1, Rent1
Domain Architecture
Description	Regulator of nonsense transcripts 1 (EC 3.6.1.-) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up- frameshift suppressor 1 homolog) (mUpf1).

ATF2_MOUSE
θ value	2.36792 (rank : 66)	NC score	0.011692 (rank : 83)
Query Neighborhood Hits	98	Target Neighborhood Hits	397	Shared Neighborhood Hits	3
SwissProt Accessions	P16951, Q64089, Q64090, Q64091	Gene names	Atf2
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-2 (Activating transcription factor 2) (cAMP response element-binding protein CRE- BP1) (MXBP protein).

DYN2_HUMAN
θ value	2.36792 (rank : 67)	NC score	0.006373 (rank : 86)
Query Neighborhood Hits	98	Target Neighborhood Hits	112	Shared Neighborhood Hits	4
SwissProt Accessions	P50570, Q7Z5S3, Q9UPH4	Gene names	DNM2, DYN2
Domain Architecture
Description	Dynamin-2 (EC 3.6.5.5).

LONM_HUMAN
θ value	2.36792 (rank : 68)	NC score	0.414647 (rank : 53)
Query Neighborhood Hits	98	Target Neighborhood Hits	130	Shared Neighborhood Hits	58
SwissProt Accessions	P36776, P36777, Q9UQ95	Gene names	PRSS15
Domain Architecture
Description	Lon protease homolog, mitochondrial precursor (EC 3.4.21.-) (Lon protease-like protein) (LONP) (LONHs).

RFC1_HUMAN
θ value	2.36792 (rank : 69)	NC score	0.114482 (rank : 61)
Query Neighborhood Hits	98	Target Neighborhood Hits	352	Shared Neighborhood Hits	46
SwissProt Accessions	P35251, Q5XKF5, Q6PKU0, Q86V41, Q86V46	Gene names	RFC1, RFC140
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (DNA-binding protein PO-GA).

RFC1_MOUSE
θ value	2.36792 (rank : 70)	NC score	0.127416 (rank : 58)
Query Neighborhood Hits	98	Target Neighborhood Hits	290	Shared Neighborhood Hits	46
SwissProt Accessions	P35601	Gene names	Rfc1, Ibf-1, Recc1
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (A1-P145) (Differentiation- specific element-binding protein) (ISRE-binding protein).

ZBT12_HUMAN
θ value	2.36792 (rank : 71)	NC score	-0.004351 (rank : 104)
Query Neighborhood Hits	98	Target Neighborhood Hits	784	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y330, Q5JQ98	Gene names	ZBTB12, C6orf46, G10, NG35
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 12 (Protein G10).

SETX_HUMAN
θ value	3.0926 (rank : 72)	NC score	0.016669 (rank : 78)
Query Neighborhood Hits	98	Target Neighborhood Hits	368	Shared Neighborhood Hits	12
SwissProt Accessions	Q7Z333, O75120, Q3KQX4, Q68DW5, Q6AZD7, Q7Z3J6, Q8WX33, Q9H9D1, Q9NVP9	Gene names	SETX, ALS4, KIAA0625, SCAR1
Domain Architecture
Description	Probable helicase senataxin (EC 3.6.1.-) (SEN1 homolog).

TULP4_HUMAN
θ value	3.0926 (rank : 73)	NC score	0.015913 (rank : 79)
Query Neighborhood Hits	98	Target Neighborhood Hits	426	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NRJ4, Q9HD22, Q9P2F0	Gene names	TULP4, KIAA1397, TUSP
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

CYLC1_HUMAN
θ value	4.03905 (rank : 74)	NC score	0.010638 (rank : 84)
Query Neighborhood Hits	98	Target Neighborhood Hits	408	Shared Neighborhood Hits	9
SwissProt Accessions	P35663, Q5JQQ9	Gene names	CYLC1, CYL, CYL1
Domain Architecture	No domain graphic available
Description	Cylicin-1 (Cylicin I) (Multiple-band polypeptide I).

TULP4_MOUSE
θ value	4.03905 (rank : 75)	NC score	0.013240 (rank : 81)
Query Neighborhood Hits	98	Target Neighborhood Hits	247	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JIL5, Q8CA75, Q922C2	Gene names	Tulp4, Tusp
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

GGA2_MOUSE
θ value	5.27518 (rank : 76)	NC score	0.005526 (rank : 89)
Query Neighborhood Hits	98	Target Neighborhood Hits	60	Shared Neighborhood Hits	2
SwissProt Accessions	Q6P5E6, Q3U374, Q6PFX3, Q6ZPY8, Q8BM76, Q9DC15	Gene names	Gga2, Kiaa1080
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-binding protein GGA2 (Golgi-localized, gamma ear-containing, ARF-binding protein 2) (Gamma-adaptin-related protein 2).

RFC4_HUMAN
θ value	5.27518 (rank : 77)	NC score	0.109131 (rank : 62)
Query Neighborhood Hits	98	Target Neighborhood Hits	64	Shared Neighborhood Hits	40
SwissProt Accessions	P35249, Q6FHX7	Gene names	RFC4
Domain Architecture
Description	Replication factor C subunit 4 (Replication factor C 37 kDa subunit) (RF-C 37 kDa subunit) (RFC37) (Activator 1 37 kDa subunit) (A1 37 kDa subunit).

RFC4_MOUSE
θ value	5.27518 (rank : 78)	NC score	0.097350 (rank : 65)
Query Neighborhood Hits	98	Target Neighborhood Hits	65	Shared Neighborhood Hits	40
SwissProt Accessions	Q99J62	Gene names	Rfc4
Domain Architecture	No domain graphic available
Description	Replication factor C subunit 4.

AQR_HUMAN
θ value	6.88961 (rank : 79)	NC score	0.034319 (rank : 74)
Query Neighborhood Hits	98	Target Neighborhood Hits	88	Shared Neighborhood Hits	15
SwissProt Accessions	O60306, Q2YDX9, Q6IRU8, Q6PIC8	Gene names	AQR, KIAA0560
Domain Architecture	No domain graphic available
Description	Intron-binding protein aquarius (Intron-binding protein of 160 kDa) (IBP160).

AQR_MOUSE
θ value	6.88961 (rank : 80)	NC score	0.035303 (rank : 70)
Query Neighborhood Hits	98	Target Neighborhood Hits	62	Shared Neighborhood Hits	15
SwissProt Accessions	Q8CFQ3, P97871, Q3U9N1, Q3ULE8, Q80TX8	Gene names	Aqr, Kiaa0560
Domain Architecture	No domain graphic available
Description	Intron-binding protein aquarius.

ASPP2_HUMAN
θ value	6.88961 (rank : 81)	NC score	-0.002373 (rank : 101)
Query Neighborhood Hits	98	Target Neighborhood Hits	1156	Shared Neighborhood Hits	8
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

ASXL1_HUMAN
θ value	6.88961 (rank : 82)	NC score	0.006292 (rank : 87)
Query Neighborhood Hits	98	Target Neighborhood Hits	260	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IXJ9, Q5JWS9, Q8IYY7, Q9H466, Q9NQF8, Q9UFJ0, Q9UFP8, Q9Y2I4	Gene names	ASXL1, KIAA0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

CO5_MOUSE
θ value	6.88961 (rank : 83)	NC score	0.003990 (rank : 92)
Query Neighborhood Hits	98	Target Neighborhood Hits	23	Shared Neighborhood Hits	2
SwissProt Accessions	P06684	Gene names	C5, Hc
Domain Architecture
Description	Complement C5 precursor (Hemolytic complement) [Contains: Complement C5 beta chain; Complement C5 alpha chain; C5a anaphylatoxin; Complement C5 alpha' chain].

M3K7_HUMAN
θ value	6.88961 (rank : 84)	NC score	-0.006098 (rank : 105)
Query Neighborhood Hits	98	Target Neighborhood Hits	892	Shared Neighborhood Hits	4
SwissProt Accessions	O43318, O43317, O43319, Q5TDN2, Q5TDN3	Gene names	MAP3K7, TAK1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta- activated kinase 1).

MCM4_HUMAN
θ value	6.88961 (rank : 85)	NC score	0.005456 (rank : 90)
Query Neighborhood Hits	98	Target Neighborhood Hits	59	Shared Neighborhood Hits	3
SwissProt Accessions	P33991, Q8NEH1, Q99658	Gene names	MCM4, CDC21
Domain Architecture
Description	DNA replication licensing factor MCM4 (CDC21 homolog) (P1-CDC21).

NAL13_HUMAN
θ value	6.88961 (rank : 86)	NC score	0.002635 (rank : 94)
Query Neighborhood Hits	98	Target Neighborhood Hits	93	Shared Neighborhood Hits	2
SwissProt Accessions	Q86W25, Q7RTR5	Gene names	NALP13, NOD14
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 13 (Nucleotide-binding oligomerization domain protein 14).

SPAG1_HUMAN
θ value	6.88961 (rank : 87)	NC score	0.003206 (rank : 93)
Query Neighborhood Hits	98	Target Neighborhood Hits	197	Shared Neighborhood Hits	4
SwissProt Accessions	Q07617, Q7Z5G1	Gene names	SPAG1
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 1 (Infertility-related sperm protein Spag-1) (HSD-3.8).

SYCP1_HUMAN
θ value	6.88961 (rank : 88)	NC score	-0.001250 (rank : 99)
Query Neighborhood Hits	98	Target Neighborhood Hits	1313	Shared Neighborhood Hits	12
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

SYNE2_HUMAN
θ value	6.88961 (rank : 89)	NC score	-0.000538 (rank : 98)
Query Neighborhood Hits	98	Target Neighborhood Hits	1323	Shared Neighborhood Hits	12
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

ZCHC6_HUMAN
θ value	6.88961 (rank : 90)	NC score	0.005539 (rank : 88)
Query Neighborhood Hits	98	Target Neighborhood Hits	142	Shared Neighborhood Hits	2
SwissProt Accessions	Q5VYS8, Q5H9T0, Q5VYS5, Q5VYS7, Q658Z9, Q659A2, Q6MZJ3, Q8N5F0, Q96N57, Q96NE8, Q9C0F2, Q9H8M6	Gene names	ZCCHC6, KIAA1711
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 6.

DHX9_HUMAN
θ value	8.99809 (rank : 91)	NC score	0.001849 (rank : 96)
Query Neighborhood Hits	98	Target Neighborhood Hits	62	Shared Neighborhood Hits	2
SwissProt Accessions	Q08211, Q5VY62, Q6PD69, Q99556	Gene names	DHX9, DDX9, NDH2
Domain Architecture
Description	ATP-dependent RNA helicase A (EC 3.6.1.-) (Nuclear DNA helicase II) (NDH II) (DEAH box protein 9).

DPYS_MOUSE
θ value	8.99809 (rank : 92)	NC score	0.002416 (rank : 95)
Query Neighborhood Hits	98	Target Neighborhood Hits	18	Shared Neighborhood Hits	2
SwissProt Accessions	Q9EQF5, Q99PP1, Q9DBK3, Q9DBP7	Gene names	Dpys
Domain Architecture
Description	Dihydropyrimidinase (EC 3.5.2.2) (DHPase) (Hydantoinase) (DHP).

IRK15_MOUSE
θ value	8.99809 (rank : 93)	NC score	0.001291 (rank : 97)
Query Neighborhood Hits	98	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	O88932, Q9JK34	Gene names	Kcnj15
Domain Architecture
Description	ATP-sensitive inward rectifier potassium channel 15 (Potassium channel, inwardly rectifying subfamily J member 15) (Inward rectifier K(+) channel Kir4.2).

KAD6_HUMAN
θ value	8.99809 (rank : 94)	NC score	0.102361 (rank : 63)
Query Neighborhood Hits	98	Target Neighborhood Hits	46	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y3D8	Gene names	AK6
Domain Architecture
Description	Adenylate kinase isoenzyme 6 (EC 2.7.4.3) (ATP-AMP transphosphorylase 6).

MCM4_MOUSE
θ value	8.99809 (rank : 95)	NC score	0.005050 (rank : 91)
Query Neighborhood Hits	98	Target Neighborhood Hits	53	Shared Neighborhood Hits	4
SwissProt Accessions	P49717, O89056	Gene names	Mcm4, Cdc21, Mcmd4
Domain Architecture
Description	DNA replication licensing factor MCM4 (CDC21 homolog) (P1-CDC21).

MLL2_HUMAN
θ value	8.99809 (rank : 96)	NC score	-0.003399 (rank : 103)
Query Neighborhood Hits	98	Target Neighborhood Hits	1788	Shared Neighborhood Hits	12
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MYH11_HUMAN
θ value	8.99809 (rank : 97)	NC score	-0.001809 (rank : 100)
Query Neighborhood Hits	98	Target Neighborhood Hits	1806	Shared Neighborhood Hits	16
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYH9_MOUSE
θ value	8.99809 (rank : 98)	NC score	-0.002418 (rank : 102)
Query Neighborhood Hits	98	Target Neighborhood Hits	1829	Shared Neighborhood Hits	19
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

KAD6_MOUSE
θ value	θ > 10 (rank : 99)	NC score	0.078038 (rank : 67)
Query Neighborhood Hits	98	Target Neighborhood Hits	34	Shared Neighborhood Hits	19
SwissProt Accessions	Q8VCP8	Gene names	Ak6
Domain Architecture	No domain graphic available
Description	Adenylate kinase isoenzyme 6 (EC 2.7.4.3) (ATP-AMP transphosphorylase 6).

RFC5_HUMAN
θ value	θ > 10 (rank : 100)	NC score	0.064511 (rank : 69)
Query Neighborhood Hits	98	Target Neighborhood Hits	60	Shared Neighborhood Hits	30
SwissProt Accessions	P40937	Gene names	RFC5
Domain Architecture
Description	Replication factor C subunit 5 (Replication factor C 36 kDa subunit) (RF-C 36 kDa subunit) (RFC36) (Activator 1 36 kDa subunit) (A1 36 kDa subunit).

RFC5_MOUSE
θ value	θ > 10 (rank : 101)	NC score	0.065424 (rank : 68)
Query Neighborhood Hits	98	Target Neighborhood Hits	58	Shared Neighborhood Hits	32
SwissProt Accessions	Q9D0F6	Gene names	Rfc5
Domain Architecture
Description	Replication factor C subunit 5 (Replication factor C 36 kDa subunit) (RF-C 36 kDa subunit) (RFC36) (Activator 1 36 kDa subunit) (A1 36 kDa subunit).

RUVB2_HUMAN
θ value	θ > 10 (rank : 102)	NC score	0.121402 (rank : 59)
Query Neighborhood Hits	98	Target Neighborhood Hits	43	Shared Neighborhood Hits	36
SwissProt Accessions	Q9Y230, Q6PK27, Q9Y361	Gene names	RUVBL2, TIP48, TIP49B
Domain Architecture
Description	RuvB-like 2 (EC 3.6.1.-) (48 kDa TATA box-binding protein-interacting protein) (48 kDa TBP-interacting protein) (TIP49b) (Repressing pontin 52) (Reptin 52) (51 kDa erythrocyte cytosolic protein) (ECP-51) (TIP60-associated protein 54-beta) (TAP54-beta).

RUVB2_MOUSE
θ value	θ > 10 (rank : 103)	NC score	0.118690 (rank : 60)
Query Neighborhood Hits	98	Target Neighborhood Hits	42	Shared Neighborhood Hits	35
SwissProt Accessions	Q9WTM5	Gene names	Ruvbl2
Domain Architecture
Description	RuvB-like 2 (EC 3.6.1.-) (p47 protein).

THNSL_HUMAN
θ value	θ > 10 (rank : 104)	NC score	0.096855 (rank : 66)
Query Neighborhood Hits	98	Target Neighborhood Hits	47	Shared Neighborhood Hits	34
SwissProt Accessions	Q8IYQ7, Q5VV21	Gene names	THNSL1
Domain Architecture	No domain graphic available
Description	Threonine synthase-like 1.

THNSL_MOUSE
θ value	θ > 10 (rank : 105)	NC score	0.098494 (rank : 64)
Query Neighborhood Hits	98	Target Neighborhood Hits	47	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BH55	Gene names	Thnsl1
Domain Architecture	No domain graphic available
Description	Threonine synthase-like 1.

Hits sorted by NC score

PEX1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	98	Target Neighborhood Hits	98	Shared Neighborhood Hits	98
SwissProt Accessions	O43933, Q96S71, Q96S72, Q96S73, Q99994	Gene names	PEX1
Domain Architecture
Description	Peroxisome biogenesis factor 1 (Peroxin-1) (Peroxisome biogenesis disorder protein 1).

TERA_HUMAN
NC score	0.965472 (rank : 2)	θ value	3.70236e-70 (rank : 2)
Query Neighborhood Hits	98	Target Neighborhood Hits	76	Shared Neighborhood Hits	63
SwissProt Accessions	P55072, Q969G7	Gene names	VCP
Domain Architecture
Description	Transitional endoplasmic reticulum ATPase (TER ATPase) (15S Mg(2+)- ATPase p97 subunit) (Valosin-containing protein) (VCP).

TERA_MOUSE
NC score	0.965464 (rank : 3)	θ value	3.70236e-70 (rank : 3)
Query Neighborhood Hits	98	Target Neighborhood Hits	76	Shared Neighborhood Hits	63
SwissProt Accessions	Q01853	Gene names	Vcp
Domain Architecture
Description	Transitional endoplasmic reticulum ATPase (TER ATPase) (15S Mg(2+)- ATPase p97 subunit) (Valosin-containing protein) (VCP).

NVL_MOUSE
NC score	0.957942 (rank : 4)	θ value	3.14151e-61 (rank : 6)
Query Neighborhood Hits	98	Target Neighborhood Hits	110	Shared Neighborhood Hits	64
SwissProt Accessions	Q9DBY8, Q3USC4, Q8BW27, Q8K2B5	Gene names	Nvl
Domain Architecture
Description	Nuclear valosin-containing protein-like (Nuclear VCP-like protein) (NVLp).

NVL_HUMAN
NC score	0.957210 (rank : 5)	θ value	4.10295e-61 (rank : 7)
Query Neighborhood Hits	98	Target Neighborhood Hits	112	Shared Neighborhood Hits	64
SwissProt Accessions	O15381, Q96EM7	Gene names	NVL
Domain Architecture
Description	Nuclear valosin-containing protein-like (Nuclear VCP-like protein) (NVLp).

PEX6_MOUSE
NC score	0.956028 (rank : 6)	θ value	3.03575e-64 (rank : 4)
Query Neighborhood Hits	98	Target Neighborhood Hits	94	Shared Neighborhood Hits	63
SwissProt Accessions	Q99LC9, Q6YNQ9	Gene names	Pex6
Domain Architecture	No domain graphic available
Description	Peroxisome assembly factor 2 (PAF-2) (Peroxisomal-type ATPase 1) (Peroxin-6) (Peroxisomal biogenesis factor 6).

PEX6_HUMAN
NC score	0.956027 (rank : 7)	θ value	2.56992e-63 (rank : 5)
Query Neighborhood Hits	98	Target Neighborhood Hits	99	Shared Neighborhood Hits	64
SwissProt Accessions	Q13608, Q8WYQ2, Q99476	Gene names	PEX6, PXAAA1
Domain Architecture
Description	Peroxisome assembly factor 2 (PAF-2) (Peroxisomal-type ATPase 1) (Peroxin-6) (Peroxisomal biogenesis factor 6).

PRS10_HUMAN
NC score	0.950720 (rank : 8)	θ value	5.38352e-45 (rank : 8)
Query Neighborhood Hits	98	Target Neighborhood Hits	95	Shared Neighborhood Hits	62
SwissProt Accessions	P62333, P49719, Q6IBU3, Q92524	Gene names	PSMC6, SUG2
Domain Architecture
Description	26S protease regulatory subunit S10B (Proteasome subunit p42) (Proteasome 26S subunit ATPase 6).

PRS10_MOUSE
NC score	0.950720 (rank : 9)	θ value	5.38352e-45 (rank : 9)
Query Neighborhood Hits	98	Target Neighborhood Hits	95	Shared Neighborhood Hits	62
SwissProt Accessions	P62334, P49719, Q3TKK1, Q810A6, Q92524, Q9CXH9	Gene names	Psmc6, Sug2
Domain Architecture
Description	26S protease regulatory subunit S10B (Proteasome subunit p42) (Proteasome 26S subunit ATPase 6).

PRS8_HUMAN
NC score	0.949876 (rank : 10)	θ value	2.04573e-44 (rank : 10)
Query Neighborhood Hits	98	Target Neighborhood Hits	117	Shared Neighborhood Hits	62
SwissProt Accessions	P62195, O35051, O43208, P47210, P52915, P52916	Gene names	PSMC5, SUG1
Domain Architecture
Description	26S protease regulatory subunit 8 (Proteasome 26S subunit ATPase 5) (Proteasome subunit p45) (p45/SUG) (Thyroid hormone receptor- interacting protein 1) (TRIP1).

PRS8_MOUSE
NC score	0.949876 (rank : 11)	θ value	2.04573e-44 (rank : 11)
Query Neighborhood Hits	98	Target Neighborhood Hits	117	Shared Neighborhood Hits	62
SwissProt Accessions	P62196, O35051, P47210, P52915, P52916, Q3UL51, Q9CWN5	Gene names	Psmc5, Sug1
Domain Architecture
Description	26S protease regulatory subunit 8 (Proteasome 26S subunit ATPase 5) (Proteasome subunit p45) (p45/SUG) (mSUG1).

PRS4_HUMAN
NC score	0.948081 (rank : 12)	θ value	9.50281e-42 (rank : 12)
Query Neighborhood Hits	98	Target Neighborhood Hits	84	Shared Neighborhood Hits	63
SwissProt Accessions	P62191, P49014, Q03527, Q6IAW0, Q96AZ3	Gene names	PSMC1
Domain Architecture
Description	26S protease regulatory subunit 4 (P26s4) (Proteasome 26S subunit ATPase 1).

PRS4_MOUSE
NC score	0.948081 (rank : 13)	θ value	9.50281e-42 (rank : 13)
Query Neighborhood Hits	98	Target Neighborhood Hits	84	Shared Neighborhood Hits	63
SwissProt Accessions	P62192, P49014, Q03527, Q96AZ3	Gene names	Psmc1
Domain Architecture
Description	26S protease regulatory subunit 4 (P26s4) (Proteasome 26S subunit ATPase 1).

PRS7_HUMAN
NC score	0.946020 (rank : 14)	θ value	5.76516e-39 (rank : 16)
Query Neighborhood Hits	98	Target Neighborhood Hits	66	Shared Neighborhood Hits	57
SwissProt Accessions	P35998	Gene names	PSMC2, MSS1
Domain Architecture
Description	26S protease regulatory subunit 7 (Proteasome 26S subunit ATPase 2) (Protein MSS1).

PRS7_MOUSE
NC score	0.946010 (rank : 15)	θ value	5.76516e-39 (rank : 17)
Query Neighborhood Hits	98	Target Neighborhood Hits	67	Shared Neighborhood Hits	57
SwissProt Accessions	P46471, O08531, Q3TGX5, Q9DBA1	Gene names	Psmc2, Mss1
Domain Architecture
Description	26S protease regulatory subunit 7 (Proteasome 26S subunit ATPase 2) (Protein MSS1).

PRS6A_MOUSE
NC score	0.945782 (rank : 16)	θ value	1.79215e-40 (rank : 15)
Query Neighborhood Hits	98	Target Neighborhood Hits	85	Shared Neighborhood Hits	61
SwissProt Accessions	O88685	Gene names	Psmc3, Tbp1
Domain Architecture
Description	26S protease regulatory subunit 6A (Proteasome 26S subunit ATPase 3) (TAT-binding protein 1) (TBP-1).

PRS6A_HUMAN
NC score	0.945598 (rank : 17)	θ value	1.3722e-40 (rank : 14)
Query Neighborhood Hits	98	Target Neighborhood Hits	87	Shared Neighborhood Hits	61
SwissProt Accessions	P17980, Q96HD3	Gene names	PSMC3, TBP1
Domain Architecture
Description	26S protease regulatory subunit 6A (Proteasome 26S subunit ATPase 3) (TAT-binding protein 1) (TBP-1) (Proteasome subunit P50).

PRS6B_HUMAN
NC score	0.943867 (rank : 18)	θ value	2.19075e-38 (rank : 18)
Query Neighborhood Hits	98	Target Neighborhood Hits	85	Shared Neighborhood Hits	57
SwissProt Accessions	P43686, Q96FV5, Q9UBM3, Q9UEX3	Gene names	PSMC4, TBP7
Domain Architecture
Description	26S protease regulatory subunit 6B (Proteasome 26S subunit ATPase 4) (MIP224) (MB67-interacting protein) (TAT-binding protein 7) (TBP-7).

PRS6B_MOUSE
NC score	0.943476 (rank : 19)	θ value	2.86122e-38 (rank : 19)
Query Neighborhood Hits	98	Target Neighborhood Hits	89	Shared Neighborhood Hits	57
SwissProt Accessions	P54775	Gene names	Psmc4, Tbp7
Domain Architecture
Description	26S protease regulatory subunit 6B (Proteasome 26S subunit ATPase 4) (MIP224) (MB67-interacting protein) (TAT-binding protein 7) (TBP-7) (CIP21).

ATAD1_HUMAN
NC score	0.928341 (rank : 20)	θ value	3.28125e-26 (rank : 40)
Query Neighborhood Hits	98	Target Neighborhood Hits	75	Shared Neighborhood Hits	60
SwissProt Accessions	Q8NBU5, Q6P4B9, Q8N3G1, Q8WYR9, Q969Y3	Gene names	ATAD1
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 1.

ATAD1_MOUSE
NC score	0.928341 (rank : 21)	θ value	3.28125e-26 (rank : 41)
Query Neighborhood Hits	98	Target Neighborhood Hits	75	Shared Neighborhood Hits	60
SwissProt Accessions	Q9D5T0, Q3U8V2, Q9D7A4	Gene names	Atad1
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 1.

AFG31_MOUSE
NC score	0.928290 (rank : 22)	θ value	1.20211e-36 (rank : 22)
Query Neighborhood Hits	98	Target Neighborhood Hits	74	Shared Neighborhood Hits	60
SwissProt Accessions	Q920A7	Gene names	Afg3l1
Domain Architecture
Description	AFG3-like protein 1 (EC 3.4.24.-).

SPG7_HUMAN
NC score	0.926367 (rank : 23)	θ value	3.06405e-32 (rank : 33)
Query Neighborhood Hits	98	Target Neighborhood Hits	71	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UQ90, O75756, Q96IB0	Gene names	SPG7, CAR, CMAR, PGN
Domain Architecture
Description	Paraplegin (EC 3.4.24.-) (Spastic paraplegia protein 7).

KATL1_MOUSE
NC score	0.925127 (rank : 24)	θ value	4.27553e-34 (rank : 28)
Query Neighborhood Hits	98	Target Neighborhood Hits	77	Shared Neighborhood Hits	62
SwissProt Accessions	Q8K0T4	Gene names	Katnal1
Domain Architecture	No domain graphic available
Description	Katanin p60 ATPase-containing subunit A-like 1 (EC 3.6.4.3) (Katanin p60 subunit A-like 1) (p60 katanin-like 1).

KATL1_HUMAN
NC score	0.924730 (rank : 25)	θ value	2.77131e-33 (rank : 32)
Query Neighborhood Hits	98	Target Neighborhood Hits	80	Shared Neighborhood Hits	62
SwissProt Accessions	Q9BW62	Gene names	KATNAL1
Domain Architecture	No domain graphic available
Description	Katanin p60 ATPase-containing subunit A-like 1 (EC 3.6.4.3) (Katanin p60 subunit A-like 1) (p60 katanin-like 1).

AFG32_HUMAN
NC score	0.924369 (rank : 26)	θ value	7.04741e-37 (rank : 20)
Query Neighborhood Hits	98	Target Neighborhood Hits	72	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Y4W6	Gene names	AFG3L2
Domain Architecture
Description	AFG3-like protein 2 (EC 3.4.24.-) (Paraplegin-like protein).

NSF_MOUSE
NC score	0.924346 (rank : 27)	θ value	1.01765e-35 (rank : 24)
Query Neighborhood Hits	98	Target Neighborhood Hits	73	Shared Neighborhood Hits	59
SwissProt Accessions	P46460	Gene names	Nsf, Skd2
Domain Architecture
Description	Vesicle-fusing ATPase (EC 3.6.4.6) (Vesicular-fusion protein NSF) (N- ethylmaleimide sensitive fusion protein) (NEM-sensitive fusion protein) (SKD2 protein).

AFG32_MOUSE
NC score	0.924055 (rank : 28)	θ value	7.04741e-37 (rank : 21)
Query Neighborhood Hits	98	Target Neighborhood Hits	73	Shared Neighborhood Hits	60
SwissProt Accessions	Q8JZQ2	Gene names	Afg3l2
Domain Architecture	No domain graphic available
Description	AFG3-like protein 2 (EC 3.4.24.-).

NSF_HUMAN
NC score	0.924029 (rank : 29)	θ value	2.96089e-35 (rank : 27)
Query Neighborhood Hits	98	Target Neighborhood Hits	74	Shared Neighborhood Hits	60
SwissProt Accessions	P46459, Q9UKZ2	Gene names	NSF
Domain Architecture
Description	Vesicle-fusing ATPase (EC 3.6.4.6) (Vesicular-fusion protein NSF) (N- ethylmaleimide sensitive fusion protein) (NEM-sensitive fusion protein).

KTNA1_HUMAN
NC score	0.922484 (rank : 30)	θ value	2.96089e-35 (rank : 26)
Query Neighborhood Hits	98	Target Neighborhood Hits	117	Shared Neighborhood Hits	62
SwissProt Accessions	O75449, Q5TFA8, Q5TFA9, Q86VN2, Q9NU52	Gene names	KATNA1
Domain Architecture	No domain graphic available
Description	Katanin p60 ATPase-containing subunit A1 (EC 3.6.4.3) (Katanin p60 subunit A1) (p60 katanin).

YMEL1_MOUSE
NC score	0.922382 (rank : 31)	θ value	1.24399e-33 (rank : 30)
Query Neighborhood Hits	98	Target Neighborhood Hits	76	Shared Neighborhood Hits	57
SwissProt Accessions	O88967, Q7TNN5	Gene names	Yme1l1
Domain Architecture
Description	ATP-dependent metalloprotease YME1L1 (EC 3.4.24.-) (YME1-like protein 1) (ATP-dependent metalloprotease FtsH1).

KTNA1_MOUSE
NC score	0.919690 (rank : 32)	θ value	2.12192e-33 (rank : 31)
Query Neighborhood Hits	98	Target Neighborhood Hits	123	Shared Neighborhood Hits	62
SwissProt Accessions	Q9WV86	Gene names	Katna1
Domain Architecture	No domain graphic available
Description	Katanin p60 ATPase-containing subunit A1 (EC 3.6.4.3) (Katanin p60 subunit A1) (p60 katanin) (Lipotransin).

YMEL1_HUMAN
NC score	0.919111 (rank : 33)	θ value	9.52487e-34 (rank : 29)
Query Neighborhood Hits	98	Target Neighborhood Hits	73	Shared Neighborhood Hits	57
SwissProt Accessions	Q96TA2, Q9H1Q0, Q9UMR9	Gene names	YME1L1, FTSH1, YME1L
Domain Architecture
Description	ATP-dependent metalloprotease YME1L1 (EC 3.4.24.-) (YME1-like protein 1) (ATP-dependent metalloprotease FtsH1) (Meg-4) (Presenilin- associated metalloprotease) (PAMP).

SPAST_HUMAN
NC score	0.915206 (rank : 34)	θ value	7.54701e-31 (rank : 37)
Query Neighborhood Hits	98	Target Neighborhood Hits	100	Shared Neighborhood Hits	60
SwissProt Accessions	Q9UBP0, Q9UPR9	Gene names	SPAST, KIAA1083, SPG4
Domain Architecture
Description	Spastin.

SPAST_MOUSE
NC score	0.914109 (rank : 35)	θ value	4.42448e-31 (rank : 36)
Query Neighborhood Hits	98	Target Neighborhood Hits	138	Shared Neighborhood Hits	60
SwissProt Accessions	Q9QYY8, Q6ZPY6, Q80VE0, Q9CVK0	Gene names	Spast, Kiaa1083, Spg4
Domain Architecture	No domain graphic available
Description	Spastin.

VPS4B_HUMAN
NC score	0.910165 (rank : 36)	θ value	1.85889e-29 (rank : 39)
Query Neighborhood Hits	98	Target Neighborhood Hits	87	Shared Neighborhood Hits	61
SwissProt Accessions	O75351, Q9GZS7	Gene names	VPS4B, SKD1, VPS42
Domain Architecture
Description	Vacuolar protein sorting-associating protein 4B (Protein SKD1).

VPS4B_MOUSE
NC score	0.909743 (rank : 37)	θ value	4.89182e-30 (rank : 38)
Query Neighborhood Hits	98	Target Neighborhood Hits	86	Shared Neighborhood Hits	60
SwissProt Accessions	P46467, Q91W22, Q9R1C9	Gene names	Vps4b, Skd1
Domain Architecture
Description	Vacuolar protein sorting-associating protein 4B (Protein SKD1).

VPS4A_HUMAN
NC score	0.909205 (rank : 38)	θ value	2.59387e-31 (rank : 34)
Query Neighborhood Hits	98	Target Neighborhood Hits	95	Shared Neighborhood Hits	61
SwissProt Accessions	Q9UN37, Q8TF07, Q9UI03, Q9Y582	Gene names	VPS4A, VPS4
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associating protein 4A (SKD2 protein) (hVPS4) (VPS4-1).

VPS4A_MOUSE
NC score	0.909196 (rank : 39)	θ value	2.59387e-31 (rank : 35)
Query Neighborhood Hits	98	Target Neighborhood Hits	94	Shared Neighborhood Hits	61
SwissProt Accessions	Q8VEJ9, Q3TXT2	Gene names	Vps4a
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associating protein 4A.

ATAD2_MOUSE
NC score	0.886312 (rank : 40)	θ value	7.79185e-36 (rank : 23)
Query Neighborhood Hits	98	Target Neighborhood Hits	167	Shared Neighborhood Hits	59
SwissProt Accessions	Q8CDM1	Gene names	Atad2
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 2.

ATAD2_HUMAN
NC score	0.868636 (rank : 41)	θ value	1.32909e-35 (rank : 25)
Query Neighborhood Hits	98	Target Neighborhood Hits	322	Shared Neighborhood Hits	63
SwissProt Accessions	Q6PL18, Q658P2, Q68CQ0, Q6PJV6, Q8N890, Q9UHS5	Gene names	ATAD2
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 2.

FIGN_MOUSE
NC score	0.866079 (rank : 42)	θ value	5.42112e-21 (rank : 43)
Query Neighborhood Hits	98	Target Neighborhood Hits	165	Shared Neighborhood Hits	54
SwissProt Accessions	Q9ERZ6, Q3TPB0, Q3UP57, Q6PCM0	Gene names	Fign
Domain Architecture	No domain graphic available
Description	Fidgetin.

FIGN_HUMAN
NC score	0.861156 (rank : 43)	θ value	2.43343e-21 (rank : 42)
Query Neighborhood Hits	98	Target Neighborhood Hits	176	Shared Neighborhood Hits	55
SwissProt Accessions	Q5HY92, Q9H6M5, Q9NVZ9	Gene names	FIGN
Domain Architecture	No domain graphic available
Description	Fidgetin.

TRP13_MOUSE
NC score	0.725020 (rank : 44)	θ value	2.13673e-09 (rank : 44)
Query Neighborhood Hits	98	Target Neighborhood Hits	81	Shared Neighborhood Hits	55
SwissProt Accessions	Q3UA06, Q3UQG6, Q9CWW8	Gene names	Trip13
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 13 (Thyroid hormone receptor interactor 13) (Trip-13).

TRP13_HUMAN
NC score	0.721824 (rank : 45)	θ value	2.79066e-09 (rank : 45)
Query Neighborhood Hits	98	Target Neighborhood Hits	81	Shared Neighborhood Hits	55
SwissProt Accessions	Q15645, O15324	Gene names	TRIP13
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 13 (Thyroid hormone receptor interactor 13) (Trip-13) (Human papillomavirus type 16 E1 protein- binding protein) (HPV16 E1 protein-binding protein) (16E1-BP).

BCS1_HUMAN
NC score	0.677290 (rank : 46)	θ value	4.92598e-06 (rank : 49)
Query Neighborhood Hits	98	Target Neighborhood Hits	61	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Y276, Q7Z2V7	Gene names	BCS1L, BCS1
Domain Architecture
Description	Mitochondrial chaperone BCS1 (BCS1-like protein) (H-BCS1).

BCS1_MOUSE
NC score	0.665702 (rank : 47)	θ value	1.43324e-05 (rank : 50)
Query Neighborhood Hits	98	Target Neighborhood Hits	64	Shared Neighborhood Hits	52
SwissProt Accessions	Q9CZP5	Gene names	Bcs1l
Domain Architecture
Description	Mitochondrial chaperone BCS1 (BCS1-like protein).

ATD3A_HUMAN
NC score	0.615996 (rank : 48)	θ value	2.88788e-06 (rank : 46)
Query Neighborhood Hits	98	Target Neighborhood Hits	248	Shared Neighborhood Hits	63
SwissProt Accessions	Q9NVI7, Q8N275, Q96A50	Gene names	ATAD3A
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 3A.

ATD3B_HUMAN
NC score	0.605094 (rank : 49)	θ value	4.92598e-06 (rank : 48)
Query Neighborhood Hits	98	Target Neighborhood Hits	340	Shared Neighborhood Hits	60
SwissProt Accessions	Q5T9A4, Q6ZRB5, Q9BUK4, Q9ULE7	Gene names	ATAD3B, KIAA1273
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 3B.

ATAD3_MOUSE
NC score	0.598061 (rank : 50)	θ value	3.77169e-06 (rank : 47)
Query Neighborhood Hits	98	Target Neighborhood Hits	326	Shared Neighborhood Hits	62
SwissProt Accessions	Q925I1, Q3UE74, Q69ZM7, Q8C6C6	Gene names	Atad3, Atad3a, Kiaa1273
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 3 (AAA-ATPase TOB3).

CLPX_HUMAN
NC score	0.418919 (rank : 51)	θ value	0.0736092 (rank : 56)
Query Neighborhood Hits	98	Target Neighborhood Hits	72	Shared Neighborhood Hits	51
SwissProt Accessions	O76031, Q9H4D9	Gene names	CLPX
Domain Architecture
Description	ATP-dependent Clp protease ATP-binding subunit ClpX-like, mitochondrial precursor.

CLPX_MOUSE
NC score	0.416891 (rank : 52)	θ value	0.0736092 (rank : 57)
Query Neighborhood Hits	98	Target Neighborhood Hits	73	Shared Neighborhood Hits	51
SwissProt Accessions	Q9JHS4, Q9WVD1	Gene names	Clpx
Domain Architecture
Description	ATP-dependent Clp protease ATP-binding subunit ClpX-like, mitochondrial precursor.

LONM_HUMAN
NC score	0.414647 (rank : 53)	θ value	2.36792 (rank : 68)
Query Neighborhood Hits	98	Target Neighborhood Hits	130	Shared Neighborhood Hits	58
SwissProt Accessions	P36776, P36777, Q9UQ95	Gene names	PRSS15
Domain Architecture
Description	Lon protease homolog, mitochondrial precursor (EC 3.4.21.-) (Lon protease-like protein) (LONP) (LONHs).

RUVB1_HUMAN
NC score	0.324012 (rank : 54)	θ value	0.0148317 (rank : 51)
Query Neighborhood Hits	98	Target Neighborhood Hits	78	Shared Neighborhood Hits	57
SwissProt Accessions	Q9Y265, Q9BSX9	Gene names	RUVBL1, NMP238, TIP49, TIP49A
Domain Architecture
Description	RuvB-like 1 (EC 3.6.1.-) (49 kDa TATA box-binding protein-interacting protein) (49 kDa TBP-interacting protein) (TIP49a) (Pontin 52) (Nuclear matrix protein 238) (NMP 238) (54 kDa erythrocyte cytosolic protein) (ECP-54) (TIP60-associated protein 54-alpha) (TAP54-alpha).

RUVB1_MOUSE
NC score	0.323971 (rank : 55)	θ value	0.0148317 (rank : 52)
Query Neighborhood Hits	98	Target Neighborhood Hits	78	Shared Neighborhood Hits	57
SwissProt Accessions	P60122, O35753	Gene names	Ruvbl1, Tip49, Tip49a
Domain Architecture
Description	RuvB-like 1 (EC 3.6.1.-) (49 kDa TATA box-binding protein-interacting protein) (49 kDa TBP-interacting protein) (TIP49a) (Pontin 52) (DNA helicase p50).

WRIP1_MOUSE
NC score	0.255434 (rank : 56)	θ value	0.0193708 (rank : 53)
Query Neighborhood Hits	98	Target Neighborhood Hits	93	Shared Neighborhood Hits	50
SwissProt Accessions	Q91XU0, Q3TCT7, Q6PDF0, Q8BUW5, Q8BWP6, Q8BY55, Q921W3, Q9EQL3	Gene names	Wrnip1, Whip
Domain Architecture	No domain graphic available
Description	ATPase WRNIP1 (Werner helicase-interacting protein 1).

WRIP1_HUMAN
NC score	0.253479 (rank : 57)	θ value	0.0252991 (rank : 54)
Query Neighborhood Hits	98	Target Neighborhood Hits	100	Shared Neighborhood Hits	50
SwissProt Accessions	Q96S55, Q53EP6, Q59ET8, Q5W0E2, Q5W0E4, Q8WV26, Q9H681, Q9NRJ6	Gene names	WRNIP1, WHIP
Domain Architecture	No domain graphic available
Description	ATPase WRNIP1 (Werner helicase-interacting protein 1).

RFC1_MOUSE
NC score	0.127416 (rank : 58)	θ value	2.36792 (rank : 70)
Query Neighborhood Hits	98	Target Neighborhood Hits	290	Shared Neighborhood Hits	46
SwissProt Accessions	P35601	Gene names	Rfc1, Ibf-1, Recc1
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (A1-P145) (Differentiation- specific element-binding protein) (ISRE-binding protein).

RUVB2_HUMAN
NC score	0.121402 (rank : 59)	θ value	θ > 10 (rank : 102)
Query Neighborhood Hits	98	Target Neighborhood Hits	43	Shared Neighborhood Hits	36
SwissProt Accessions	Q9Y230, Q6PK27, Q9Y361	Gene names	RUVBL2, TIP48, TIP49B
Domain Architecture
Description	RuvB-like 2 (EC 3.6.1.-) (48 kDa TATA box-binding protein-interacting protein) (48 kDa TBP-interacting protein) (TIP49b) (Repressing pontin 52) (Reptin 52) (51 kDa erythrocyte cytosolic protein) (ECP-51) (TIP60-associated protein 54-beta) (TAP54-beta).

RUVB2_MOUSE
NC score	0.118690 (rank : 60)	θ value	θ > 10 (rank : 103)
Query Neighborhood Hits	98	Target Neighborhood Hits	42	Shared Neighborhood Hits	35
SwissProt Accessions	Q9WTM5	Gene names	Ruvbl2
Domain Architecture
Description	RuvB-like 2 (EC 3.6.1.-) (p47 protein).

RFC1_HUMAN
NC score	0.114482 (rank : 61)	θ value	2.36792 (rank : 69)
Query Neighborhood Hits	98	Target Neighborhood Hits	352	Shared Neighborhood Hits	46
SwissProt Accessions	P35251, Q5XKF5, Q6PKU0, Q86V41, Q86V46	Gene names	RFC1, RFC140
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (DNA-binding protein PO-GA).

RFC4_HUMAN
NC score	0.109131 (rank : 62)	θ value	5.27518 (rank : 77)
Query Neighborhood Hits	98	Target Neighborhood Hits	64	Shared Neighborhood Hits	40
SwissProt Accessions	P35249, Q6FHX7	Gene names	RFC4
Domain Architecture
Description	Replication factor C subunit 4 (Replication factor C 37 kDa subunit) (RF-C 37 kDa subunit) (RFC37) (Activator 1 37 kDa subunit) (A1 37 kDa subunit).

KAD6_HUMAN
NC score	0.102361 (rank : 63)	θ value	8.99809 (rank : 94)
Query Neighborhood Hits	98	Target Neighborhood Hits	46	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y3D8	Gene names	AK6
Domain Architecture
Description	Adenylate kinase isoenzyme 6 (EC 2.7.4.3) (ATP-AMP transphosphorylase 6).

THNSL_MOUSE
NC score	0.098494 (rank : 64)	θ value	θ > 10 (rank : 105)
Query Neighborhood Hits	98	Target Neighborhood Hits	47	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BH55	Gene names	Thnsl1
Domain Architecture	No domain graphic available
Description	Threonine synthase-like 1.

RFC4_MOUSE
NC score	0.097350 (rank : 65)	θ value	5.27518 (rank : 78)
Query Neighborhood Hits	98	Target Neighborhood Hits	65	Shared Neighborhood Hits	40
SwissProt Accessions	Q99J62	Gene names	Rfc4
Domain Architecture	No domain graphic available
Description	Replication factor C subunit 4.

THNSL_HUMAN
NC score	0.096855 (rank : 66)	θ value	θ > 10 (rank : 104)
Query Neighborhood Hits	98	Target Neighborhood Hits	47	Shared Neighborhood Hits	34
SwissProt Accessions	Q8IYQ7, Q5VV21	Gene names	THNSL1
Domain Architecture	No domain graphic available
Description	Threonine synthase-like 1.

KAD6_MOUSE
NC score	0.078038 (rank : 67)	θ value	θ > 10 (rank : 99)
Query Neighborhood Hits	98	Target Neighborhood Hits	34	Shared Neighborhood Hits	19
SwissProt Accessions	Q8VCP8	Gene names	Ak6
Domain Architecture	No domain graphic available
Description	Adenylate kinase isoenzyme 6 (EC 2.7.4.3) (ATP-AMP transphosphorylase 6).

RFC5_MOUSE
NC score	0.065424 (rank : 68)	θ value	θ > 10 (rank : 101)
Query Neighborhood Hits	98	Target Neighborhood Hits	58	Shared Neighborhood Hits	32
SwissProt Accessions	Q9D0F6	Gene names	Rfc5
Domain Architecture
Description	Replication factor C subunit 5 (Replication factor C 36 kDa subunit) (RF-C 36 kDa subunit) (RFC36) (Activator 1 36 kDa subunit) (A1 36 kDa subunit).

RFC5_HUMAN
NC score	0.064511 (rank : 69)	θ value	θ > 10 (rank : 100)
Query Neighborhood Hits	98	Target Neighborhood Hits	60	Shared Neighborhood Hits	30
SwissProt Accessions	P40937	Gene names	RFC5
Domain Architecture
Description	Replication factor C subunit 5 (Replication factor C 36 kDa subunit) (RF-C 36 kDa subunit) (RFC36) (Activator 1 36 kDa subunit) (A1 36 kDa subunit).

AQR_MOUSE
NC score	0.035303 (rank : 70)	θ value	6.88961 (rank : 80)
Query Neighborhood Hits	98	Target Neighborhood Hits	62	Shared Neighborhood Hits	15
SwissProt Accessions	Q8CFQ3, P97871, Q3U9N1, Q3ULE8, Q80TX8	Gene names	Aqr, Kiaa0560
Domain Architecture	No domain graphic available
Description	Intron-binding protein aquarius.

DHE3_HUMAN
NC score	0.035023 (rank : 71)	θ value	0.62314 (rank : 58)
Query Neighborhood Hits	98	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	P00367	Gene names	GLUD1, GLUD
Domain Architecture
Description	Glutamate dehydrogenase 1, mitochondrial precursor (EC 1.4.1.3) (GDH).

DHE3_MOUSE
NC score	0.034967 (rank : 72)	θ value	0.62314 (rank : 59)
Query Neighborhood Hits	98	Target Neighborhood Hits	9	Shared Neighborhood Hits	4
SwissProt Accessions	P26443, Q8C273	Gene names	Glud1, Glud
Domain Architecture
Description	Glutamate dehydrogenase 1, mitochondrial precursor (EC 1.4.1.3) (GDH).

DHE4_HUMAN
NC score	0.034947 (rank : 73)	θ value	0.62314 (rank : 60)
Query Neighborhood Hits	98	Target Neighborhood Hits	13	Shared Neighborhood Hits	4
SwissProt Accessions	P49448, Q9UDQ4	Gene names	GLUD2, GLUDP1
Domain Architecture
Description	Glutamate dehydrogenase 2, mitochondrial precursor (EC 1.4.1.3) (GDH).

AQR_HUMAN
NC score	0.034319 (rank : 74)	θ value	6.88961 (rank : 79)
Query Neighborhood Hits	98	Target Neighborhood Hits	88	Shared Neighborhood Hits	15
SwissProt Accessions	O60306, Q2YDX9, Q6IRU8, Q6PIC8	Gene names	AQR, KIAA0560
Domain Architecture	No domain graphic available
Description	Intron-binding protein aquarius (Intron-binding protein of 160 kDa) (IBP160).

RENT1_MOUSE
NC score	0.033871 (rank : 75)	θ value	1.81305 (rank : 65)
Query Neighborhood Hits	98	Target Neighborhood Hits	54	Shared Neighborhood Hits	14
SwissProt Accessions	Q9EPU0, Q99PR4	Gene names	Upf1, Rent1
Domain Architecture
Description	Regulator of nonsense transcripts 1 (EC 3.6.1.-) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up- frameshift suppressor 1 homolog) (mUpf1).

RENT1_HUMAN
NC score	0.033155 (rank : 76)	θ value	1.38821 (rank : 61)
Query Neighborhood Hits	98	Target Neighborhood Hits	51	Shared Neighborhood Hits	14
SwissProt Accessions	Q92900, O00239, O43343, Q86Z25, Q92842	Gene names	UPF1, KIAA0221, RENT1
Domain Architecture
Description	Regulator of nonsense transcripts 1 (EC 3.6.1.-) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up- frameshift suppressor 1 homolog) (hUpf1).

ALO17_HUMAN
NC score	0.032837 (rank : 77)	θ value	0.0736092 (rank : 55)
Query Neighborhood Hits	98	Target Neighborhood Hits	317	Shared Neighborhood Hits	4
SwissProt Accessions	Q9HCF4, Q69YK7, Q8IWF4, Q8IZX1, Q8IZX2, Q8N406	Gene names	KIAA1618, ALO17
Domain Architecture	No domain graphic available
Description	Protein ALO17 (ALK lymphoma oligomerization partner on chromosome 17).

SETX_HUMAN
NC score	0.016669 (rank : 78)	θ value	3.0926 (rank : 72)
Query Neighborhood Hits	98	Target Neighborhood Hits	368	Shared Neighborhood Hits	12
SwissProt Accessions	Q7Z333, O75120, Q3KQX4, Q68DW5, Q6AZD7, Q7Z3J6, Q8WX33, Q9H9D1, Q9NVP9	Gene names	SETX, ALS4, KIAA0625, SCAR1
Domain Architecture
Description	Probable helicase senataxin (EC 3.6.1.-) (SEN1 homolog).

TULP4_HUMAN
NC score	0.015913 (rank : 79)	θ value	3.0926 (rank : 73)
Query Neighborhood Hits	98	Target Neighborhood Hits	426	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NRJ4, Q9HD22, Q9P2F0	Gene names	TULP4, KIAA1397, TUSP
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

GP156_HUMAN
NC score	0.014422 (rank : 80)	θ value	1.81305 (rank : 63)
Query Neighborhood Hits	98	Target Neighborhood Hits	84	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NFN8, Q86SN6	Gene names	GPR156, GABABL, PGR28
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 156 (GABAB-related G-protein coupled receptor) (G-protein coupled receptor PGR28).

TULP4_MOUSE
NC score	0.013240 (rank : 81)	θ value	4.03905 (rank : 75)
Query Neighborhood Hits	98	Target Neighborhood Hits	247	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JIL5, Q8CA75, Q922C2	Gene names	Tulp4, Tusp
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

ATF2_HUMAN
NC score	0.012198 (rank : 82)	θ value	1.81305 (rank : 62)
Query Neighborhood Hits	98	Target Neighborhood Hits	402	Shared Neighborhood Hits	3
SwissProt Accessions	P15336, Q13000	Gene names	ATF2, CREB2, CREBP1
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-2 (Activating transcription factor 2) (cAMP response element-binding protein CRE- BP1) (HB16).

ATF2_MOUSE
NC score	0.011692 (rank : 83)	θ value	2.36792 (rank : 66)
Query Neighborhood Hits	98	Target Neighborhood Hits	397	Shared Neighborhood Hits	3
SwissProt Accessions	P16951, Q64089, Q64090, Q64091	Gene names	Atf2
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-2 (Activating transcription factor 2) (cAMP response element-binding protein CRE- BP1) (MXBP protein).

CYLC1_HUMAN
NC score	0.010638 (rank : 84)	θ value	4.03905 (rank : 74)
Query Neighborhood Hits	98	Target Neighborhood Hits	408	Shared Neighborhood Hits	9
SwissProt Accessions	P35663, Q5JQQ9	Gene names	CYLC1, CYL, CYL1
Domain Architecture	No domain graphic available
Description	Cylicin-1 (Cylicin I) (Multiple-band polypeptide I).

NPAS1_MOUSE
NC score	0.007456 (rank : 85)	θ value	1.81305 (rank : 64)
Query Neighborhood Hits	98	Target Neighborhood Hits	63	Shared Neighborhood Hits	3
SwissProt Accessions	P97459	Gene names	Npas1
Domain Architecture
Description	Neuronal PAS domain-containing protein 1 (Neuronal PAS1).

DYN2_HUMAN
NC score	0.006373 (rank : 86)	θ value	2.36792 (rank : 67)
Query Neighborhood Hits	98	Target Neighborhood Hits	112	Shared Neighborhood Hits	4
SwissProt Accessions	P50570, Q7Z5S3, Q9UPH4	Gene names	DNM2, DYN2
Domain Architecture
Description	Dynamin-2 (EC 3.6.5.5).

ASXL1_HUMAN
NC score	0.006292 (rank : 87)	θ value	6.88961 (rank : 82)
Query Neighborhood Hits	98	Target Neighborhood Hits	260	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IXJ9, Q5JWS9, Q8IYY7, Q9H466, Q9NQF8, Q9UFJ0, Q9UFP8, Q9Y2I4	Gene names	ASXL1, KIAA0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

ZCHC6_HUMAN
NC score	0.005539 (rank : 88)	θ value	6.88961 (rank : 90)
Query Neighborhood Hits	98	Target Neighborhood Hits	142	Shared Neighborhood Hits	2
SwissProt Accessions	Q5VYS8, Q5H9T0, Q5VYS5, Q5VYS7, Q658Z9, Q659A2, Q6MZJ3, Q8N5F0, Q96N57, Q96NE8, Q9C0F2, Q9H8M6	Gene names	ZCCHC6, KIAA1711
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 6.

GGA2_MOUSE
NC score	0.005526 (rank : 89)	θ value	5.27518 (rank : 76)
Query Neighborhood Hits	98	Target Neighborhood Hits	60	Shared Neighborhood Hits	2
SwissProt Accessions	Q6P5E6, Q3U374, Q6PFX3, Q6ZPY8, Q8BM76, Q9DC15	Gene names	Gga2, Kiaa1080
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-binding protein GGA2 (Golgi-localized, gamma ear-containing, ARF-binding protein 2) (Gamma-adaptin-related protein 2).

MCM4_HUMAN
NC score	0.005456 (rank : 90)	θ value	6.88961 (rank : 85)
Query Neighborhood Hits	98	Target Neighborhood Hits	59	Shared Neighborhood Hits	3
SwissProt Accessions	P33991, Q8NEH1, Q99658	Gene names	MCM4, CDC21
Domain Architecture
Description	DNA replication licensing factor MCM4 (CDC21 homolog) (P1-CDC21).

MCM4_MOUSE
NC score	0.005050 (rank : 91)	θ value	8.99809 (rank : 95)
Query Neighborhood Hits	98	Target Neighborhood Hits	53	Shared Neighborhood Hits	4
SwissProt Accessions	P49717, O89056	Gene names	Mcm4, Cdc21, Mcmd4
Domain Architecture
Description	DNA replication licensing factor MCM4 (CDC21 homolog) (P1-CDC21).

CO5_MOUSE
NC score	0.003990 (rank : 92)	θ value	6.88961 (rank : 83)
Query Neighborhood Hits	98	Target Neighborhood Hits	23	Shared Neighborhood Hits	2
SwissProt Accessions	P06684	Gene names	C5, Hc
Domain Architecture
Description	Complement C5 precursor (Hemolytic complement) [Contains: Complement C5 beta chain; Complement C5 alpha chain; C5a anaphylatoxin; Complement C5 alpha' chain].

SPAG1_HUMAN
NC score	0.003206 (rank : 93)	θ value	6.88961 (rank : 87)
Query Neighborhood Hits	98	Target Neighborhood Hits	197	Shared Neighborhood Hits	4
SwissProt Accessions	Q07617, Q7Z5G1	Gene names	SPAG1
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 1 (Infertility-related sperm protein Spag-1) (HSD-3.8).

NAL13_HUMAN
NC score	0.002635 (rank : 94)	θ value	6.88961 (rank : 86)
Query Neighborhood Hits	98	Target Neighborhood Hits	93	Shared Neighborhood Hits	2
SwissProt Accessions	Q86W25, Q7RTR5	Gene names	NALP13, NOD14
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 13 (Nucleotide-binding oligomerization domain protein 14).

DPYS_MOUSE
NC score	0.002416 (rank : 95)	θ value	8.99809 (rank : 92)
Query Neighborhood Hits	98	Target Neighborhood Hits	18	Shared Neighborhood Hits	2
SwissProt Accessions	Q9EQF5, Q99PP1, Q9DBK3, Q9DBP7	Gene names	Dpys
Domain Architecture
Description	Dihydropyrimidinase (EC 3.5.2.2) (DHPase) (Hydantoinase) (DHP).

DHX9_HUMAN
NC score	0.001849 (rank : 96)	θ value	8.99809 (rank : 91)
Query Neighborhood Hits	98	Target Neighborhood Hits	62	Shared Neighborhood Hits	2
SwissProt Accessions	Q08211, Q5VY62, Q6PD69, Q99556	Gene names	DHX9, DDX9, NDH2
Domain Architecture
Description	ATP-dependent RNA helicase A (EC 3.6.1.-) (Nuclear DNA helicase II) (NDH II) (DEAH box protein 9).

IRK15_MOUSE
NC score	0.001291 (rank : 97)	θ value	8.99809 (rank : 93)
Query Neighborhood Hits	98	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	O88932, Q9JK34	Gene names	Kcnj15
Domain Architecture
Description	ATP-sensitive inward rectifier potassium channel 15 (Potassium channel, inwardly rectifying subfamily J member 15) (Inward rectifier K(+) channel Kir4.2).

SYNE2_HUMAN
NC score	-0.000538 (rank : 98)	θ value	6.88961 (rank : 89)
Query Neighborhood Hits	98	Target Neighborhood Hits	1323	Shared Neighborhood Hits	12
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

SYCP1_HUMAN
NC score	-0.001250 (rank : 99)	θ value	6.88961 (rank : 88)
Query Neighborhood Hits	98	Target Neighborhood Hits	1313	Shared Neighborhood Hits	12
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

MYH11_HUMAN
NC score	-0.001809 (rank : 100)	θ value	8.99809 (rank : 97)
Query Neighborhood Hits	98	Target Neighborhood Hits	1806	Shared Neighborhood Hits	16
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

ASPP2_HUMAN
NC score	-0.002373 (rank : 101)	θ value	6.88961 (rank : 81)
Query Neighborhood Hits	98	Target Neighborhood Hits	1156	Shared Neighborhood Hits	8
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

MYH9_MOUSE
NC score	-0.002418 (rank : 102)	θ value	8.99809 (rank : 98)
Query Neighborhood Hits	98	Target Neighborhood Hits	1829	Shared Neighborhood Hits	19
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

MLL2_HUMAN
NC score	-0.003399 (rank : 103)	θ value	8.99809 (rank : 96)
Query Neighborhood Hits	98	Target Neighborhood Hits	1788	Shared Neighborhood Hits	12
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

ZBT12_HUMAN
NC score	-0.004351 (rank : 104)	θ value	2.36792 (rank : 71)
Query Neighborhood Hits	98	Target Neighborhood Hits	784	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y330, Q5JQ98	Gene names	ZBTB12, C6orf46, G10, NG35
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 12 (Protein G10).

M3K7_HUMAN
NC score	-0.006098 (rank : 105)	θ value	6.88961 (rank : 84)
Query Neighborhood Hits	98	Target Neighborhood Hits	892	Shared Neighborhood Hits	4
SwissProt Accessions	O43318, O43317, O43319, Q5TDN2, Q5TDN3	Gene names	MAP3K7, TAK1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta- activated kinase 1).