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Network neighborhood for query Sequence : CO5_MOUSE

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CO5_MOUSE
SwissProt Accessions	P06684	Gene names	C5, Hc
Domain Architecture
Description	Complement C5 precursor (Hemolytic complement) [Contains: Complement C5 beta chain; Complement C5 alpha chain; C5a anaphylatoxin; Complement C5 alpha' chain].
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CO3_HUMAN
θ value	0 (rank : 1)	NC score	0.955594 (rank : 4)
Query Neighborhood Hits	23	Target Neighborhood Hits	36	Shared Neighborhood Hits	12
SwissProt Accessions	P01024	Gene names	C3
Domain Architecture
Description	Complement C3 precursor [Contains: Complement C3 beta chain; Complement C3 alpha chain; C3a anaphylatoxin; Complement C3b alpha' chain; Complement C3c fragment; Complement C3dg fragment; Complement C3g fragment; Complement C3d fragment; Complement C3f fragment].

CO3_MOUSE
θ value	0 (rank : 2)	NC score	0.955686 (rank : 3)
Query Neighborhood Hits	23	Target Neighborhood Hits	33	Shared Neighborhood Hits	12
SwissProt Accessions	P01027, Q61370	Gene names	C3
Domain Architecture
Description	Complement C3 precursor (HSE-MSF) [Contains: Complement C3 beta chain; Complement C3 alpha chain; C3a anaphylatoxin; Complement C3b alpha' chain; Complement C3c fragment; Complement C3dg fragment; Complement C3g fragment; Complement C3d fragment; Complement C3, isoform Short; Complement C3f fragment].

CO5_HUMAN
θ value	0 (rank : 3)	NC score	0.997130 (rank : 2)
Query Neighborhood Hits	23	Target Neighborhood Hits	25	Shared Neighborhood Hits	14
SwissProt Accessions	P01031	Gene names	C5
Domain Architecture
Description	Complement C5 precursor [Contains: Complement C5 beta chain; Complement C5 alpha chain; C5a anaphylatoxin; Complement C5 alpha' chain].

CO5_MOUSE
θ value	0 (rank : 4)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	23	Target Neighborhood Hits	23	Shared Neighborhood Hits	23
SwissProt Accessions	P06684	Gene names	C5, Hc
Domain Architecture
Description	Complement C5 precursor (Hemolytic complement) [Contains: Complement C5 beta chain; Complement C5 alpha chain; C5a anaphylatoxin; Complement C5 alpha' chain].

CO4B_HUMAN
θ value	1.08919e-146 (rank : 5)	NC score	0.926505 (rank : 6)
Query Neighborhood Hits	23	Target Neighborhood Hits	47	Shared Neighborhood Hits	12
SwissProt Accessions	P0C0L5, P01028, P78445, Q13160, Q13906, Q14033, Q14835, Q9NPK5, Q9UIP5	Gene names	C4B
Domain Architecture	No domain graphic available
Description	Complement C4-B precursor (Basic complement C4) [Contains: Complement C4 beta chain; Complement C4-B alpha chain; C4a anaphylatoxin; C4b-B; C4d-B; Complement C4 gamma chain].

CO4A_HUMAN
θ value	1.42253e-146 (rank : 6)	NC score	0.926363 (rank : 7)
Query Neighborhood Hits	23	Target Neighborhood Hits	47	Shared Neighborhood Hits	12
SwissProt Accessions	P0C0L4, P01028, P78445, Q13160, Q13906, Q14033, Q14835, Q5JQM8, Q9NPK5, Q9UIP5	Gene names	C4A
Domain Architecture	No domain graphic available
Description	Complement C4-A precursor (Acidic complement C4) [Contains: Complement C4 beta chain; Complement C4-A alpha chain; C4a anaphylatoxin; C4b-A; C4d-A; Complement C4 gamma chain].

CO4B_MOUSE
θ value	8.65023e-136 (rank : 7)	NC score	0.931042 (rank : 5)
Query Neighborhood Hits	23	Target Neighborhood Hits	36	Shared Neighborhood Hits	12
SwissProt Accessions	P01029, Q31201, Q61372, Q61859, Q62353	Gene names	C4b, C4
Domain Architecture
Description	Complement C4-B precursor [Contains: Complement C4 beta chain; Complement C4 alpha chain; C4a anaphylatoxin; Complement C4 gamma chain].

A2MG_HUMAN
θ value	1.60224e-81 (rank : 8)	NC score	0.846661 (rank : 8)
Query Neighborhood Hits	23	Target Neighborhood Hits	32	Shared Neighborhood Hits	12
SwissProt Accessions	P01023, Q13677, Q59F47, Q5QTS0, Q68DN2, Q6PIY3, Q6PN97	Gene names	A2M
Domain Architecture
Description	Alpha-2-macroglobulin precursor (Alpha-2-M).

PZP_HUMAN
θ value	6.96618e-77 (rank : 9)	NC score	0.829864 (rank : 10)
Query Neighborhood Hits	23	Target Neighborhood Hits	36	Shared Neighborhood Hits	12
SwissProt Accessions	P20742, Q15273	Gene names	PZP
Domain Architecture
Description	Pregnancy zone protein precursor.

MUG1_MOUSE
θ value	1.31376e-75 (rank : 10)	NC score	0.830264 (rank : 9)
Query Neighborhood Hits	23	Target Neighborhood Hits	40	Shared Neighborhood Hits	12
SwissProt Accessions	P28665	Gene names	Mug1, Mug-1
Domain Architecture
Description	Murinoglobulin-1 precursor (MuG1).

A2MG_MOUSE
θ value	9.81109e-47 (rank : 11)	NC score	0.814743 (rank : 11)
Query Neighborhood Hits	23	Target Neighborhood Hits	33	Shared Neighborhood Hits	12
SwissProt Accessions	Q61838, Q60628	Gene names	A2m
Domain Architecture
Description	Alpha-2-macroglobulin precursor (Alpha-2-M) [Contains: Alpha-2- macroglobulin 165 kDa subunit; Alpha-2-macroglobulin 35 kDa subunit].

MUG2_MOUSE
θ value	2.85459e-46 (rank : 12)	NC score	0.807577 (rank : 12)
Query Neighborhood Hits	23	Target Neighborhood Hits	26	Shared Neighborhood Hits	12
SwissProt Accessions	P28666	Gene names	Mug2, Mug-2
Domain Architecture
Description	Murinoglobulin-2 precursor (MuG2).

IL6RB_HUMAN
θ value	0.62314 (rank : 13)	NC score	0.020035 (rank : 16)
Query Neighborhood Hits	23	Target Neighborhood Hits	181	Shared Neighborhood Hits	3
SwissProt Accessions	P40189, Q9UQ41	Gene names	IL6ST
Domain Architecture
Description	Interleukin-6 receptor beta chain precursor (IL-6R-beta) (Interleukin 6 signal transducer) (Membrane glycoprotein 130) (gp130) (Oncostatin M receptor) (CD130 antigen) (CDw130).

CI097_HUMAN
θ value	1.06291 (rank : 14)	NC score	0.024540 (rank : 13)
Query Neighborhood Hits	23	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	Q5T7W7, Q6ZQZ6, Q8IYM3, Q8WY73, Q96ML6, Q96MU1	Gene names	C9orf97
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf97.

BNC2_HUMAN
θ value	1.81305 (rank : 15)	NC score	0.012629 (rank : 20)
Query Neighborhood Hits	23	Target Neighborhood Hits	439	Shared Neighborhood Hits	2
SwissProt Accessions	Q6ZN30, Q6T3A3, Q8NAR2, Q9H6J0, Q9NXV0	Gene names	BNC2
Domain Architecture	No domain graphic available
Description	Zinc finger protein basonuclin-2.

RIOK2_HUMAN
θ value	1.81305 (rank : 16)	NC score	0.024462 (rank : 14)
Query Neighborhood Hits	23	Target Neighborhood Hits	125	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BVS4, Q9NUT0	Gene names	RIOK2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase RIO2 (EC 2.7.11.1) (RIO kinase 2).

DLDH_MOUSE
θ value	3.0926 (rank : 17)	NC score	0.015353 (rank : 19)
Query Neighborhood Hits	23	Target Neighborhood Hits	35	Shared Neighborhood Hits	3
SwissProt Accessions	O08749	Gene names	Dld
Domain Architecture
Description	Dihydrolipoyl dehydrogenase, mitochondrial precursor (EC 1.8.1.4) (Dihydrolipoamide dehydrogenase).

GIDRP_MOUSE
θ value	3.0926 (rank : 18)	NC score	0.015533 (rank : 18)
Query Neighborhood Hits	23	Target Neighborhood Hits	96	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BJM3, Q3UGJ8, Q5U5U8	Gene names	Gidrp88, D19Ertd386e
Domain Architecture	No domain graphic available
Description	Growth inhibition and differentiation-related protein 88 homolog.

RIOK2_MOUSE
θ value	4.03905 (rank : 19)	NC score	0.021899 (rank : 15)
Query Neighborhood Hits	23	Target Neighborhood Hits	82	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CQS5, Q91XF3	Gene names	Riok2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase RIO2 (EC 2.7.11.1) (RIO kinase 2).

HTRA2_HUMAN
θ value	5.27518 (rank : 20)	NC score	0.008330 (rank : 21)
Query Neighborhood Hits	23	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	O43464, Q9HBZ4, Q9P0Y3, Q9P0Y4	Gene names	HTRA2, OMI, PRSS25
Domain Architecture
Description	Serine protease HTRA2, mitochondrial precursor (EC 3.4.21.-) (High temperature requirement protein A2) (HtrA2) (Omi stress-regulated endoprotease) (Serine proteinase OMI).

DLDH_HUMAN
θ value	6.88961 (rank : 21)	NC score	0.019562 (rank : 17)
Query Neighborhood Hits	23	Target Neighborhood Hits	34	Shared Neighborhood Hits	4
SwissProt Accessions	P09622, Q14131, Q14167	Gene names	DLD, GCSL, LAD, PHE3
Domain Architecture
Description	Dihydrolipoyl dehydrogenase, mitochondrial precursor (EC 1.8.1.4) (Dihydrolipoamide dehydrogenase) (Glycine cleavage system L protein).

MUC2_HUMAN
θ value	6.88961 (rank : 22)	NC score	0.002366 (rank : 23)
Query Neighborhood Hits	23	Target Neighborhood Hits	906	Shared Neighborhood Hits	2
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

PEX1_HUMAN
θ value	6.88961 (rank : 23)	NC score	0.003990 (rank : 22)
Query Neighborhood Hits	23	Target Neighborhood Hits	98	Shared Neighborhood Hits	2
SwissProt Accessions	O43933, Q96S71, Q96S72, Q96S73, Q99994	Gene names	PEX1
Domain Architecture
Description	Peroxisome biogenesis factor 1 (Peroxin-1) (Peroxisome biogenesis disorder protein 1).

Hits sorted by NC score

CO5_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 4)
Query Neighborhood Hits	23	Target Neighborhood Hits	23	Shared Neighborhood Hits	23
SwissProt Accessions	P06684	Gene names	C5, Hc
Domain Architecture
Description	Complement C5 precursor (Hemolytic complement) [Contains: Complement C5 beta chain; Complement C5 alpha chain; C5a anaphylatoxin; Complement C5 alpha' chain].

CO5_HUMAN
NC score	0.997130 (rank : 2)	θ value	0 (rank : 3)
Query Neighborhood Hits	23	Target Neighborhood Hits	25	Shared Neighborhood Hits	14
SwissProt Accessions	P01031	Gene names	C5
Domain Architecture
Description	Complement C5 precursor [Contains: Complement C5 beta chain; Complement C5 alpha chain; C5a anaphylatoxin; Complement C5 alpha' chain].

CO3_MOUSE
NC score	0.955686 (rank : 3)	θ value	0 (rank : 2)
Query Neighborhood Hits	23	Target Neighborhood Hits	33	Shared Neighborhood Hits	12
SwissProt Accessions	P01027, Q61370	Gene names	C3
Domain Architecture
Description	Complement C3 precursor (HSE-MSF) [Contains: Complement C3 beta chain; Complement C3 alpha chain; C3a anaphylatoxin; Complement C3b alpha' chain; Complement C3c fragment; Complement C3dg fragment; Complement C3g fragment; Complement C3d fragment; Complement C3, isoform Short; Complement C3f fragment].

CO3_HUMAN
NC score	0.955594 (rank : 4)	θ value	0 (rank : 1)
Query Neighborhood Hits	23	Target Neighborhood Hits	36	Shared Neighborhood Hits	12
SwissProt Accessions	P01024	Gene names	C3
Domain Architecture
Description	Complement C3 precursor [Contains: Complement C3 beta chain; Complement C3 alpha chain; C3a anaphylatoxin; Complement C3b alpha' chain; Complement C3c fragment; Complement C3dg fragment; Complement C3g fragment; Complement C3d fragment; Complement C3f fragment].

CO4B_MOUSE
NC score	0.931042 (rank : 5)	θ value	8.65023e-136 (rank : 7)
Query Neighborhood Hits	23	Target Neighborhood Hits	36	Shared Neighborhood Hits	12
SwissProt Accessions	P01029, Q31201, Q61372, Q61859, Q62353	Gene names	C4b, C4
Domain Architecture
Description	Complement C4-B precursor [Contains: Complement C4 beta chain; Complement C4 alpha chain; C4a anaphylatoxin; Complement C4 gamma chain].

CO4B_HUMAN
NC score	0.926505 (rank : 6)	θ value	1.08919e-146 (rank : 5)
Query Neighborhood Hits	23	Target Neighborhood Hits	47	Shared Neighborhood Hits	12
SwissProt Accessions	P0C0L5, P01028, P78445, Q13160, Q13906, Q14033, Q14835, Q9NPK5, Q9UIP5	Gene names	C4B
Domain Architecture	No domain graphic available
Description	Complement C4-B precursor (Basic complement C4) [Contains: Complement C4 beta chain; Complement C4-B alpha chain; C4a anaphylatoxin; C4b-B; C4d-B; Complement C4 gamma chain].

CO4A_HUMAN
NC score	0.926363 (rank : 7)	θ value	1.42253e-146 (rank : 6)
Query Neighborhood Hits	23	Target Neighborhood Hits	47	Shared Neighborhood Hits	12
SwissProt Accessions	P0C0L4, P01028, P78445, Q13160, Q13906, Q14033, Q14835, Q5JQM8, Q9NPK5, Q9UIP5	Gene names	C4A
Domain Architecture	No domain graphic available
Description	Complement C4-A precursor (Acidic complement C4) [Contains: Complement C4 beta chain; Complement C4-A alpha chain; C4a anaphylatoxin; C4b-A; C4d-A; Complement C4 gamma chain].

A2MG_HUMAN
NC score	0.846661 (rank : 8)	θ value	1.60224e-81 (rank : 8)
Query Neighborhood Hits	23	Target Neighborhood Hits	32	Shared Neighborhood Hits	12
SwissProt Accessions	P01023, Q13677, Q59F47, Q5QTS0, Q68DN2, Q6PIY3, Q6PN97	Gene names	A2M
Domain Architecture
Description	Alpha-2-macroglobulin precursor (Alpha-2-M).

MUG1_MOUSE
NC score	0.830264 (rank : 9)	θ value	1.31376e-75 (rank : 10)
Query Neighborhood Hits	23	Target Neighborhood Hits	40	Shared Neighborhood Hits	12
SwissProt Accessions	P28665	Gene names	Mug1, Mug-1
Domain Architecture
Description	Murinoglobulin-1 precursor (MuG1).

PZP_HUMAN
NC score	0.829864 (rank : 10)	θ value	6.96618e-77 (rank : 9)
Query Neighborhood Hits	23	Target Neighborhood Hits	36	Shared Neighborhood Hits	12
SwissProt Accessions	P20742, Q15273	Gene names	PZP
Domain Architecture
Description	Pregnancy zone protein precursor.

A2MG_MOUSE
NC score	0.814743 (rank : 11)	θ value	9.81109e-47 (rank : 11)
Query Neighborhood Hits	23	Target Neighborhood Hits	33	Shared Neighborhood Hits	12
SwissProt Accessions	Q61838, Q60628	Gene names	A2m
Domain Architecture
Description	Alpha-2-macroglobulin precursor (Alpha-2-M) [Contains: Alpha-2- macroglobulin 165 kDa subunit; Alpha-2-macroglobulin 35 kDa subunit].

MUG2_MOUSE
NC score	0.807577 (rank : 12)	θ value	2.85459e-46 (rank : 12)
Query Neighborhood Hits	23	Target Neighborhood Hits	26	Shared Neighborhood Hits	12
SwissProt Accessions	P28666	Gene names	Mug2, Mug-2
Domain Architecture
Description	Murinoglobulin-2 precursor (MuG2).

CI097_HUMAN
NC score	0.024540 (rank : 13)	θ value	1.06291 (rank : 14)
Query Neighborhood Hits	23	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	Q5T7W7, Q6ZQZ6, Q8IYM3, Q8WY73, Q96ML6, Q96MU1	Gene names	C9orf97
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf97.

RIOK2_HUMAN
NC score	0.024462 (rank : 14)	θ value	1.81305 (rank : 16)
Query Neighborhood Hits	23	Target Neighborhood Hits	125	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BVS4, Q9NUT0	Gene names	RIOK2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase RIO2 (EC 2.7.11.1) (RIO kinase 2).

RIOK2_MOUSE
NC score	0.021899 (rank : 15)	θ value	4.03905 (rank : 19)
Query Neighborhood Hits	23	Target Neighborhood Hits	82	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CQS5, Q91XF3	Gene names	Riok2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase RIO2 (EC 2.7.11.1) (RIO kinase 2).

IL6RB_HUMAN
NC score	0.020035 (rank : 16)	θ value	0.62314 (rank : 13)
Query Neighborhood Hits	23	Target Neighborhood Hits	181	Shared Neighborhood Hits	3
SwissProt Accessions	P40189, Q9UQ41	Gene names	IL6ST
Domain Architecture
Description	Interleukin-6 receptor beta chain precursor (IL-6R-beta) (Interleukin 6 signal transducer) (Membrane glycoprotein 130) (gp130) (Oncostatin M receptor) (CD130 antigen) (CDw130).

DLDH_HUMAN
NC score	0.019562 (rank : 17)	θ value	6.88961 (rank : 21)
Query Neighborhood Hits	23	Target Neighborhood Hits	34	Shared Neighborhood Hits	4
SwissProt Accessions	P09622, Q14131, Q14167	Gene names	DLD, GCSL, LAD, PHE3
Domain Architecture
Description	Dihydrolipoyl dehydrogenase, mitochondrial precursor (EC 1.8.1.4) (Dihydrolipoamide dehydrogenase) (Glycine cleavage system L protein).

GIDRP_MOUSE
NC score	0.015533 (rank : 18)	θ value	3.0926 (rank : 18)
Query Neighborhood Hits	23	Target Neighborhood Hits	96	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BJM3, Q3UGJ8, Q5U5U8	Gene names	Gidrp88, D19Ertd386e
Domain Architecture	No domain graphic available
Description	Growth inhibition and differentiation-related protein 88 homolog.

DLDH_MOUSE
NC score	0.015353 (rank : 19)	θ value	3.0926 (rank : 17)
Query Neighborhood Hits	23	Target Neighborhood Hits	35	Shared Neighborhood Hits	3
SwissProt Accessions	O08749	Gene names	Dld
Domain Architecture
Description	Dihydrolipoyl dehydrogenase, mitochondrial precursor (EC 1.8.1.4) (Dihydrolipoamide dehydrogenase).

BNC2_HUMAN
NC score	0.012629 (rank : 20)	θ value	1.81305 (rank : 15)
Query Neighborhood Hits	23	Target Neighborhood Hits	439	Shared Neighborhood Hits	2
SwissProt Accessions	Q6ZN30, Q6T3A3, Q8NAR2, Q9H6J0, Q9NXV0	Gene names	BNC2
Domain Architecture	No domain graphic available
Description	Zinc finger protein basonuclin-2.

HTRA2_HUMAN
NC score	0.008330 (rank : 21)	θ value	5.27518 (rank : 20)
Query Neighborhood Hits	23	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	O43464, Q9HBZ4, Q9P0Y3, Q9P0Y4	Gene names	HTRA2, OMI, PRSS25
Domain Architecture
Description	Serine protease HTRA2, mitochondrial precursor (EC 3.4.21.-) (High temperature requirement protein A2) (HtrA2) (Omi stress-regulated endoprotease) (Serine proteinase OMI).

PEX1_HUMAN
NC score	0.003990 (rank : 22)	θ value	6.88961 (rank : 23)
Query Neighborhood Hits	23	Target Neighborhood Hits	98	Shared Neighborhood Hits	2
SwissProt Accessions	O43933, Q96S71, Q96S72, Q96S73, Q99994	Gene names	PEX1
Domain Architecture
Description	Peroxisome biogenesis factor 1 (Peroxin-1) (Peroxisome biogenesis disorder protein 1).

MUC2_HUMAN
NC score	0.002366 (rank : 23)	θ value	6.88961 (rank : 22)
Query Neighborhood Hits	23	Target Neighborhood Hits	906	Shared Neighborhood Hits	2
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).