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Network neighborhood for query Sequence : CO4B_HUMAN

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CO4B_HUMAN
SwissProt Accessions	P0C0L5, P01028, P78445, Q13160, Q13906, Q14033, Q14835, Q9NPK5, Q9UIP5	Gene names	C4B
Domain Architecture	No domain graphic available
Description	Complement C4-B precursor (Basic complement C4) [Contains: Complement C4 beta chain; Complement C4-B alpha chain; C4a anaphylatoxin; C4b-B; C4d-B; Complement C4 gamma chain].
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CO4A_HUMAN
θ value	0 (rank : 1)	NC score	0.999961 (rank : 2)
Query Neighborhood Hits	47	Target Neighborhood Hits	47	Shared Neighborhood Hits	47
SwissProt Accessions	P0C0L4, P01028, P78445, Q13160, Q13906, Q14033, Q14835, Q5JQM8, Q9NPK5, Q9UIP5	Gene names	C4A
Domain Architecture	No domain graphic available
Description	Complement C4-A precursor (Acidic complement C4) [Contains: Complement C4 beta chain; Complement C4-A alpha chain; C4a anaphylatoxin; C4b-A; C4d-A; Complement C4 gamma chain].

CO4B_HUMAN
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	47	Target Neighborhood Hits	47	Shared Neighborhood Hits	47
SwissProt Accessions	P0C0L5, P01028, P78445, Q13160, Q13906, Q14033, Q14835, Q9NPK5, Q9UIP5	Gene names	C4B
Domain Architecture	No domain graphic available
Description	Complement C4-B precursor (Basic complement C4) [Contains: Complement C4 beta chain; Complement C4-B alpha chain; C4a anaphylatoxin; C4b-B; C4d-B; Complement C4 gamma chain].

CO4B_MOUSE
θ value	0 (rank : 3)	NC score	0.995806 (rank : 3)
Query Neighborhood Hits	47	Target Neighborhood Hits	36	Shared Neighborhood Hits	13
SwissProt Accessions	P01029, Q31201, Q61372, Q61859, Q62353	Gene names	C4b, C4
Domain Architecture
Description	Complement C4-B precursor [Contains: Complement C4 beta chain; Complement C4 alpha chain; C4a anaphylatoxin; Complement C4 gamma chain].

CO3_HUMAN
θ value	2.24492e-184 (rank : 4)	NC score	0.944662 (rank : 4)
Query Neighborhood Hits	47	Target Neighborhood Hits	36	Shared Neighborhood Hits	12
SwissProt Accessions	P01024	Gene names	C3
Domain Architecture
Description	Complement C3 precursor [Contains: Complement C3 beta chain; Complement C3 alpha chain; C3a anaphylatoxin; Complement C3b alpha' chain; Complement C3c fragment; Complement C3dg fragment; Complement C3g fragment; Complement C3d fragment; Complement C3f fragment].

CO3_MOUSE
θ value	1.72287e-176 (rank : 5)	NC score	0.942561 (rank : 5)
Query Neighborhood Hits	47	Target Neighborhood Hits	33	Shared Neighborhood Hits	12
SwissProt Accessions	P01027, Q61370	Gene names	C3
Domain Architecture
Description	Complement C3 precursor (HSE-MSF) [Contains: Complement C3 beta chain; Complement C3 alpha chain; C3a anaphylatoxin; Complement C3b alpha' chain; Complement C3c fragment; Complement C3dg fragment; Complement C3g fragment; Complement C3d fragment; Complement C3, isoform Short; Complement C3f fragment].

CO5_MOUSE
θ value	1.08919e-146 (rank : 6)	NC score	0.926505 (rank : 6)
Query Neighborhood Hits	47	Target Neighborhood Hits	23	Shared Neighborhood Hits	12
SwissProt Accessions	P06684	Gene names	C5, Hc
Domain Architecture
Description	Complement C5 precursor (Hemolytic complement) [Contains: Complement C5 beta chain; Complement C5 alpha chain; C5a anaphylatoxin; Complement C5 alpha' chain].

CO5_HUMAN
θ value	1.21547e-113 (rank : 7)	NC score	0.917772 (rank : 7)
Query Neighborhood Hits	47	Target Neighborhood Hits	25	Shared Neighborhood Hits	12
SwissProt Accessions	P01031	Gene names	C5
Domain Architecture
Description	Complement C5 precursor [Contains: Complement C5 beta chain; Complement C5 alpha chain; C5a anaphylatoxin; Complement C5 alpha' chain].

A2MG_HUMAN
θ value	2.39424e-77 (rank : 8)	NC score	0.821869 (rank : 8)
Query Neighborhood Hits	47	Target Neighborhood Hits	32	Shared Neighborhood Hits	12
SwissProt Accessions	P01023, Q13677, Q59F47, Q5QTS0, Q68DN2, Q6PIY3, Q6PN97	Gene names	A2M
Domain Architecture
Description	Alpha-2-macroglobulin precursor (Alpha-2-M).

PZP_HUMAN
θ value	2.94036e-59 (rank : 9)	NC score	0.801937 (rank : 9)
Query Neighborhood Hits	47	Target Neighborhood Hits	36	Shared Neighborhood Hits	12
SwissProt Accessions	P20742, Q15273	Gene names	PZP
Domain Architecture
Description	Pregnancy zone protein precursor.

A2MG_MOUSE
θ value	5.02714e-51 (rank : 10)	NC score	0.791978 (rank : 11)
Query Neighborhood Hits	47	Target Neighborhood Hits	33	Shared Neighborhood Hits	12
SwissProt Accessions	Q61838, Q60628	Gene names	A2m
Domain Architecture
Description	Alpha-2-macroglobulin precursor (Alpha-2-M) [Contains: Alpha-2- macroglobulin 165 kDa subunit; Alpha-2-macroglobulin 35 kDa subunit].

MUG2_MOUSE
θ value	1.04822e-48 (rank : 11)	NC score	0.780404 (rank : 12)
Query Neighborhood Hits	47	Target Neighborhood Hits	26	Shared Neighborhood Hits	12
SwissProt Accessions	P28666	Gene names	Mug2, Mug-2
Domain Architecture
Description	Murinoglobulin-2 precursor (MuG2).

MUG1_MOUSE
θ value	2.3352e-48 (rank : 12)	NC score	0.793185 (rank : 10)
Query Neighborhood Hits	47	Target Neighborhood Hits	40	Shared Neighborhood Hits	12
SwissProt Accessions	P28665	Gene names	Mug1, Mug-1
Domain Architecture
Description	Murinoglobulin-1 precursor (MuG1).

ABI2_MOUSE
θ value	0.0961366 (rank : 13)	NC score	0.035150 (rank : 13)
Query Neighborhood Hits	47	Target Neighborhood Hits	266	Shared Neighborhood Hits	4
SwissProt Accessions	P62484, Q6PHU3	Gene names	Abi2
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2).

NCOR2_HUMAN
θ value	0.813845 (rank : 14)	NC score	0.019459 (rank : 20)
Query Neighborhood Hits	47	Target Neighborhood Hits	870	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

STUB1_MOUSE
θ value	0.813845 (rank : 15)	NC score	0.031652 (rank : 14)
Query Neighborhood Hits	47	Target Neighborhood Hits	97	Shared Neighborhood Hits	5
SwissProt Accessions	Q9WUD1, Q9DCJ0	Gene names	Stub1, Chip
Domain Architecture	No domain graphic available
Description	STIP1 homology and U box-containing protein 1 (EC 6.3.2.-) (STIP1 homology and U-box-containing protein 1) (Carboxy terminus of Hsp70- interacting protein) (E3 ubiquitin protein ligase CHIP).

ABI2_HUMAN
θ value	1.06291 (rank : 16)	NC score	0.025365 (rank : 15)
Query Neighborhood Hits	47	Target Neighborhood Hits	350	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NYB9, Q13147, Q13249, Q13801, Q9BV70	Gene names	ABI2, ARGBPIA
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1).

MTF1_HUMAN
θ value	1.38821 (rank : 17)	NC score	0.003107 (rank : 42)
Query Neighborhood Hits	47	Target Neighborhood Hits	814	Shared Neighborhood Hits	8
SwissProt Accessions	Q14872, Q96CB1	Gene names	MTF1
Domain Architecture	No domain graphic available
Description	Metal-regulatory transcription factor 1 (Transcription factor MTF-1) (MRE-binding transcription factor).

UBP31_HUMAN
θ value	1.38821 (rank : 18)	NC score	0.015796 (rank : 22)
Query Neighborhood Hits	47	Target Neighborhood Hits	293	Shared Neighborhood Hits	5
SwissProt Accessions	Q70CQ4, Q6AW97, Q6ZTC0, Q6ZTN2, Q9ULL7	Gene names	USP31, KIAA1203
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 31 (EC 3.1.2.15) (Ubiquitin thioesterase 31) (Ubiquitin-specific-processing protease 31) (Deubiquitinating enzyme 31).

AMOT_HUMAN
θ value	1.81305 (rank : 19)	NC score	0.014141 (rank : 24)
Query Neighborhood Hits	47	Target Neighborhood Hits	712	Shared Neighborhood Hits	4
SwissProt Accessions	Q4VCS5, Q504X5, Q9HD27, Q9UPT1	Gene names	AMOT, KIAA1071
Domain Architecture	No domain graphic available
Description	Angiomotin.

CILP1_HUMAN
θ value	1.81305 (rank : 20)	NC score	0.020633 (rank : 19)
Query Neighborhood Hits	47	Target Neighborhood Hits	266	Shared Neighborhood Hits	6
SwissProt Accessions	O75339, Q6UW99, Q8IYI5	Gene names	CILP
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) (Cartilage intermediate-layer protein) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

KLF12_MOUSE
θ value	2.36792 (rank : 21)	NC score	0.003995 (rank : 40)
Query Neighborhood Hits	47	Target Neighborhood Hits	721	Shared Neighborhood Hits	8
SwissProt Accessions	O35738	Gene names	Klf12, Ap2rep
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 12 (Transcriptional repressor AP-2rep).

ZF106_HUMAN
θ value	3.0926 (rank : 22)	NC score	0.012935 (rank : 26)
Query Neighborhood Hits	47	Target Neighborhood Hits	470	Shared Neighborhood Hits	9
SwissProt Accessions	Q9H2Y7, Q6NSD9, Q6PEK1, Q86T43, Q86T45, Q86T50, Q86T58, Q86TA9, Q96M37, Q9H7B8	Gene names	ZFP106, ZNF474
Domain Architecture	No domain graphic available
Description	Zinc finger protein 106 homolog (Zfp-106) (Zinc finger protein 474).

KLF12_HUMAN
θ value	4.03905 (rank : 23)	NC score	0.003098 (rank : 43)
Query Neighborhood Hits	47	Target Neighborhood Hits	717	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y4X4, Q5VZM7, Q9UHZ0	Gene names	KLF12, AP2REP
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 12 (Transcriptional repressor AP-2rep).

PTPRM_HUMAN
θ value	4.03905 (rank : 24)	NC score	0.005983 (rank : 36)
Query Neighborhood Hits	47	Target Neighborhood Hits	244	Shared Neighborhood Hits	5
SwissProt Accessions	P28827	Gene names	PTPRM, PTPRL1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

RNF25_MOUSE
θ value	4.03905 (rank : 25)	NC score	0.021161 (rank : 18)
Query Neighborhood Hits	47	Target Neighborhood Hits	106	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QZR0, Q3TAL8, Q9DCW7	Gene names	Rnf25
Domain Architecture
Description	RING finger protein 25 (EC 6.3.2.-) (RING finger protein AO7).

CSPG4_HUMAN
θ value	5.27518 (rank : 26)	NC score	0.010935 (rank : 30)
Query Neighborhood Hits	47	Target Neighborhood Hits	112	Shared Neighborhood Hits	3
SwissProt Accessions	Q6UVK1, Q92675	Gene names	CSPG4, MCSP
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 4 precursor (Chondroitin sulfate proteoglycan NG2) (Melanoma chondroitin sulfate proteoglycan) (Melanoma-associated chondroitin sulfate proteoglycan).

PEX6_MOUSE
θ value	5.27518 (rank : 27)	NC score	0.007104 (rank : 33)
Query Neighborhood Hits	47	Target Neighborhood Hits	94	Shared Neighborhood Hits	4
SwissProt Accessions	Q99LC9, Q6YNQ9	Gene names	Pex6
Domain Architecture	No domain graphic available
Description	Peroxisome assembly factor 2 (PAF-2) (Peroxisomal-type ATPase 1) (Peroxin-6) (Peroxisomal biogenesis factor 6).

TF3A_HUMAN
θ value	5.27518 (rank : 28)	NC score	0.001091 (rank : 45)
Query Neighborhood Hits	47	Target Neighborhood Hits	726	Shared Neighborhood Hits	8
SwissProt Accessions	Q92664, Q12963, Q13097	Gene names	GTF3A
Domain Architecture	No domain graphic available
Description	Transcription factor IIIA (Factor A) (TFIIIA).

UBN1_HUMAN
θ value	5.27518 (rank : 29)	NC score	0.021183 (rank : 17)
Query Neighborhood Hits	47	Target Neighborhood Hits	170	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NPG3, Q13079, Q9P1P7	Gene names	UBN1
Domain Architecture	No domain graphic available
Description	Ubinuclein (Ubiquitously expressed nuclear protein) (VT4).

CA103_HUMAN
θ value	6.88961 (rank : 30)	NC score	0.015336 (rank : 23)
Query Neighborhood Hits	47	Target Neighborhood Hits	82	Shared Neighborhood Hits	4
SwissProt Accessions	Q5T3J3, Q86XS4, Q8N3B6, Q96HT4, Q9NUM5, Q9NV32	Gene names	C1orf103, RIF1
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf103 (Receptor-interacting factor 1).

CYR61_MOUSE
θ value	6.88961 (rank : 31)	NC score	0.008525 (rank : 32)
Query Neighborhood Hits	47	Target Neighborhood Hits	156	Shared Neighborhood Hits	4
SwissProt Accessions	P18406	Gene names	Cyr61, Ccn1, Igfbp10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (3CH61).

DTX2_MOUSE
θ value	6.88961 (rank : 32)	NC score	0.010996 (rank : 29)
Query Neighborhood Hits	47	Target Neighborhood Hits	76	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R3P2, Q9CZV3, Q9ER07, Q9ER08	Gene names	Dtx2
Domain Architecture
Description	Protein deltex-2 (Deltex-2) (Deltex2) (mDTX2).

MGR7_HUMAN
θ value	6.88961 (rank : 33)	NC score	0.006752 (rank : 35)
Query Neighborhood Hits	47	Target Neighborhood Hits	52	Shared Neighborhood Hits	4
SwissProt Accessions	Q14831, Q8NFS2, Q8NFS3, Q8NFS4	Gene names	GRM7, GPRC1G, MGLUR7
Domain Architecture
Description	Metabotropic glutamate receptor 7 precursor (mGluR7).

MGR7_MOUSE
θ value	6.88961 (rank : 34)	NC score	0.006757 (rank : 34)
Query Neighborhood Hits	47	Target Neighborhood Hits	53	Shared Neighborhood Hits	4
SwissProt Accessions	Q68ED2	Gene names	Grm7, Gprc1g, Mglur7
Domain Architecture	No domain graphic available
Description	Metabotropic glutamate receptor 7 precursor (mGluR7).

PTPRM_MOUSE
θ value	6.88961 (rank : 35)	NC score	0.004926 (rank : 39)
Query Neighborhood Hits	47	Target Neighborhood Hits	238	Shared Neighborhood Hits	5
SwissProt Accessions	P28828	Gene names	Ptprm
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

S2A4R_HUMAN
θ value	6.88961 (rank : 36)	NC score	0.021687 (rank : 16)
Query Neighborhood Hits	47	Target Neighborhood Hits	54	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NR83, Q6F6I6, Q6F6I7, Q6GTK5, Q8TAH5, Q8WVW7, Q96QD3, Q9BV85	Gene names	SLC2A4RG, HDBP1
Domain Architecture	No domain graphic available
Description	SLC2A4 regulator (GLUT4 enhancer factor) (GEF) (Huntington disease gene regulatory region-binding protein 1) (HDBP-1).

STUB1_HUMAN
θ value	6.88961 (rank : 37)	NC score	0.018343 (rank : 21)
Query Neighborhood Hits	47	Target Neighborhood Hits	99	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UNE7, O60526, Q969U2, Q9HBT1	Gene names	STUB1, CHIP
Domain Architecture	No domain graphic available
Description	STIP1 homology and U box-containing protein 1 (EC 6.3.2.-) (STIP1 homology and U-box-containing protein 1) (Carboxy terminus of Hsp70- interacting protein) (E3 ubiquitin protein ligase CHIP) (CLL- associated antigen KW-8) (Antigen NY-CO-7).

TOM70_HUMAN
θ value	6.88961 (rank : 38)	NC score	0.011656 (rank : 28)
Query Neighborhood Hits	47	Target Neighborhood Hits	127	Shared Neighborhood Hits	5
SwissProt Accessions	O94826	Gene names	TOMM70A, KIAA0719
Domain Architecture
Description	Mitochondrial precursor proteins import receptor (Translocase of outer membrane TOM70).

CBP_HUMAN
θ value	8.99809 (rank : 39)	NC score	0.004936 (rank : 38)
Query Neighborhood Hits	47	Target Neighborhood Hits	941	Shared Neighborhood Hits	8
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CILP1_MOUSE
θ value	8.99809 (rank : 40)	NC score	0.012875 (rank : 27)
Query Neighborhood Hits	47	Target Neighborhood Hits	282	Shared Neighborhood Hits	6
SwissProt Accessions	Q66K08, Q7TSS0, Q7TSS1, Q8BV01	Gene names	Cilp
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

MTF1_MOUSE
θ value	8.99809 (rank : 41)	NC score	0.000886 (rank : 46)
Query Neighborhood Hits	47	Target Neighborhood Hits	785	Shared Neighborhood Hits	8
SwissProt Accessions	Q07243	Gene names	Mtf1, Mtf-1
Domain Architecture	No domain graphic available
Description	Metal-regulatory transcription factor 1 (Transcription factor MTF-1) (MRE-binding transcription factor).

MUC5B_HUMAN
θ value	8.99809 (rank : 42)	NC score	0.005178 (rank : 37)
Query Neighborhood Hits	47	Target Neighborhood Hits	1020	Shared Neighborhood Hits	13
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

MYLK_HUMAN
θ value	8.99809 (rank : 43)	NC score	-0.001923 (rank : 47)
Query Neighborhood Hits	47	Target Neighborhood Hits	1328	Shared Neighborhood Hits	8
SwissProt Accessions	Q15746, O95796, O95797, O95798, O95799, Q14844, Q16794, Q5MY99, Q5MYA0, Q7Z4J0, Q9C0L5, Q9UBG5, Q9UIT9	Gene names	MYLK, MLCK
Domain Architecture
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

PGCB_HUMAN
θ value	8.99809 (rank : 44)	NC score	0.003291 (rank : 41)
Query Neighborhood Hits	47	Target Neighborhood Hits	478	Shared Neighborhood Hits	4
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

PLCG_HUMAN
θ value	8.99809 (rank : 45)	NC score	0.008566 (rank : 31)
Query Neighborhood Hits	47	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	Q643R3, O43412, Q7Z4P4, Q8IUL7, Q8TB38	Gene names	AGPAT7, AYTL3
Domain Architecture	No domain graphic available
Description	1-acyl-sn-glycerol-3-phosphate acyltransferase eta (EC 2.3.1.51) (1- AGP acyltransferase 7) (1-AGPAT 7) (Lysophosphatidic acid acyltransferase-eta) (LPAAT-eta) (Acyltransferase-like 3).

QORX_HUMAN
θ value	8.99809 (rank : 46)	NC score	0.013775 (rank : 25)
Query Neighborhood Hits	47	Target Neighborhood Hits	35	Shared Neighborhood Hits	4
SwissProt Accessions	Q53FA7, O14679, O14685, Q38G78, Q6JLE7, Q9BWB8	Gene names	TP53I3, PIG3
Domain Architecture	No domain graphic available
Description	Putative quinone oxidoreductase (EC 1.-.-.-) (Tumor protein p53- inducible protein 3) (p53-induced protein 3).

TMPS9_MOUSE
θ value	8.99809 (rank : 47)	NC score	0.001389 (rank : 44)
Query Neighborhood Hits	47	Target Neighborhood Hits	296	Shared Neighborhood Hits	5
SwissProt Accessions	P69525	Gene names	Tmprss9
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 9 (EC 3.4.21.-) (Polyserase-1) (Polyserine protease 1) (Polyserase-I) [Contains: Serase-1; Serase-2; Serase-3].

Hits sorted by NC score

CO4B_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	47	Target Neighborhood Hits	47	Shared Neighborhood Hits	47
SwissProt Accessions	P0C0L5, P01028, P78445, Q13160, Q13906, Q14033, Q14835, Q9NPK5, Q9UIP5	Gene names	C4B
Domain Architecture	No domain graphic available
Description	Complement C4-B precursor (Basic complement C4) [Contains: Complement C4 beta chain; Complement C4-B alpha chain; C4a anaphylatoxin; C4b-B; C4d-B; Complement C4 gamma chain].

CO4A_HUMAN
NC score	0.999961 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	47	Target Neighborhood Hits	47	Shared Neighborhood Hits	47
SwissProt Accessions	P0C0L4, P01028, P78445, Q13160, Q13906, Q14033, Q14835, Q5JQM8, Q9NPK5, Q9UIP5	Gene names	C4A
Domain Architecture	No domain graphic available
Description	Complement C4-A precursor (Acidic complement C4) [Contains: Complement C4 beta chain; Complement C4-A alpha chain; C4a anaphylatoxin; C4b-A; C4d-A; Complement C4 gamma chain].

CO4B_MOUSE
NC score	0.995806 (rank : 3)	θ value	0 (rank : 3)
Query Neighborhood Hits	47	Target Neighborhood Hits	36	Shared Neighborhood Hits	13
SwissProt Accessions	P01029, Q31201, Q61372, Q61859, Q62353	Gene names	C4b, C4
Domain Architecture
Description	Complement C4-B precursor [Contains: Complement C4 beta chain; Complement C4 alpha chain; C4a anaphylatoxin; Complement C4 gamma chain].

CO3_HUMAN
NC score	0.944662 (rank : 4)	θ value	2.24492e-184 (rank : 4)
Query Neighborhood Hits	47	Target Neighborhood Hits	36	Shared Neighborhood Hits	12
SwissProt Accessions	P01024	Gene names	C3
Domain Architecture
Description	Complement C3 precursor [Contains: Complement C3 beta chain; Complement C3 alpha chain; C3a anaphylatoxin; Complement C3b alpha' chain; Complement C3c fragment; Complement C3dg fragment; Complement C3g fragment; Complement C3d fragment; Complement C3f fragment].

CO3_MOUSE
NC score	0.942561 (rank : 5)	θ value	1.72287e-176 (rank : 5)
Query Neighborhood Hits	47	Target Neighborhood Hits	33	Shared Neighborhood Hits	12
SwissProt Accessions	P01027, Q61370	Gene names	C3
Domain Architecture
Description	Complement C3 precursor (HSE-MSF) [Contains: Complement C3 beta chain; Complement C3 alpha chain; C3a anaphylatoxin; Complement C3b alpha' chain; Complement C3c fragment; Complement C3dg fragment; Complement C3g fragment; Complement C3d fragment; Complement C3, isoform Short; Complement C3f fragment].

CO5_MOUSE
NC score	0.926505 (rank : 6)	θ value	1.08919e-146 (rank : 6)
Query Neighborhood Hits	47	Target Neighborhood Hits	23	Shared Neighborhood Hits	12
SwissProt Accessions	P06684	Gene names	C5, Hc
Domain Architecture
Description	Complement C5 precursor (Hemolytic complement) [Contains: Complement C5 beta chain; Complement C5 alpha chain; C5a anaphylatoxin; Complement C5 alpha' chain].

CO5_HUMAN
NC score	0.917772 (rank : 7)	θ value	1.21547e-113 (rank : 7)
Query Neighborhood Hits	47	Target Neighborhood Hits	25	Shared Neighborhood Hits	12
SwissProt Accessions	P01031	Gene names	C5
Domain Architecture
Description	Complement C5 precursor [Contains: Complement C5 beta chain; Complement C5 alpha chain; C5a anaphylatoxin; Complement C5 alpha' chain].

A2MG_HUMAN
NC score	0.821869 (rank : 8)	θ value	2.39424e-77 (rank : 8)
Query Neighborhood Hits	47	Target Neighborhood Hits	32	Shared Neighborhood Hits	12
SwissProt Accessions	P01023, Q13677, Q59F47, Q5QTS0, Q68DN2, Q6PIY3, Q6PN97	Gene names	A2M
Domain Architecture
Description	Alpha-2-macroglobulin precursor (Alpha-2-M).

PZP_HUMAN
NC score	0.801937 (rank : 9)	θ value	2.94036e-59 (rank : 9)
Query Neighborhood Hits	47	Target Neighborhood Hits	36	Shared Neighborhood Hits	12
SwissProt Accessions	P20742, Q15273	Gene names	PZP
Domain Architecture
Description	Pregnancy zone protein precursor.

MUG1_MOUSE
NC score	0.793185 (rank : 10)	θ value	2.3352e-48 (rank : 12)
Query Neighborhood Hits	47	Target Neighborhood Hits	40	Shared Neighborhood Hits	12
SwissProt Accessions	P28665	Gene names	Mug1, Mug-1
Domain Architecture
Description	Murinoglobulin-1 precursor (MuG1).

A2MG_MOUSE
NC score	0.791978 (rank : 11)	θ value	5.02714e-51 (rank : 10)
Query Neighborhood Hits	47	Target Neighborhood Hits	33	Shared Neighborhood Hits	12
SwissProt Accessions	Q61838, Q60628	Gene names	A2m
Domain Architecture
Description	Alpha-2-macroglobulin precursor (Alpha-2-M) [Contains: Alpha-2- macroglobulin 165 kDa subunit; Alpha-2-macroglobulin 35 kDa subunit].

MUG2_MOUSE
NC score	0.780404 (rank : 12)	θ value	1.04822e-48 (rank : 11)
Query Neighborhood Hits	47	Target Neighborhood Hits	26	Shared Neighborhood Hits	12
SwissProt Accessions	P28666	Gene names	Mug2, Mug-2
Domain Architecture
Description	Murinoglobulin-2 precursor (MuG2).

ABI2_MOUSE
NC score	0.035150 (rank : 13)	θ value	0.0961366 (rank : 13)
Query Neighborhood Hits	47	Target Neighborhood Hits	266	Shared Neighborhood Hits	4
SwissProt Accessions	P62484, Q6PHU3	Gene names	Abi2
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2).

STUB1_MOUSE
NC score	0.031652 (rank : 14)	θ value	0.813845 (rank : 15)
Query Neighborhood Hits	47	Target Neighborhood Hits	97	Shared Neighborhood Hits	5
SwissProt Accessions	Q9WUD1, Q9DCJ0	Gene names	Stub1, Chip
Domain Architecture	No domain graphic available
Description	STIP1 homology and U box-containing protein 1 (EC 6.3.2.-) (STIP1 homology and U-box-containing protein 1) (Carboxy terminus of Hsp70- interacting protein) (E3 ubiquitin protein ligase CHIP).

ABI2_HUMAN
NC score	0.025365 (rank : 15)	θ value	1.06291 (rank : 16)
Query Neighborhood Hits	47	Target Neighborhood Hits	350	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NYB9, Q13147, Q13249, Q13801, Q9BV70	Gene names	ABI2, ARGBPIA
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1).

S2A4R_HUMAN
NC score	0.021687 (rank : 16)	θ value	6.88961 (rank : 36)
Query Neighborhood Hits	47	Target Neighborhood Hits	54	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NR83, Q6F6I6, Q6F6I7, Q6GTK5, Q8TAH5, Q8WVW7, Q96QD3, Q9BV85	Gene names	SLC2A4RG, HDBP1
Domain Architecture	No domain graphic available
Description	SLC2A4 regulator (GLUT4 enhancer factor) (GEF) (Huntington disease gene regulatory region-binding protein 1) (HDBP-1).

UBN1_HUMAN
NC score	0.021183 (rank : 17)	θ value	5.27518 (rank : 29)
Query Neighborhood Hits	47	Target Neighborhood Hits	170	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NPG3, Q13079, Q9P1P7	Gene names	UBN1
Domain Architecture	No domain graphic available
Description	Ubinuclein (Ubiquitously expressed nuclear protein) (VT4).

RNF25_MOUSE
NC score	0.021161 (rank : 18)	θ value	4.03905 (rank : 25)
Query Neighborhood Hits	47	Target Neighborhood Hits	106	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QZR0, Q3TAL8, Q9DCW7	Gene names	Rnf25
Domain Architecture
Description	RING finger protein 25 (EC 6.3.2.-) (RING finger protein AO7).

CILP1_HUMAN
NC score	0.020633 (rank : 19)	θ value	1.81305 (rank : 20)
Query Neighborhood Hits	47	Target Neighborhood Hits	266	Shared Neighborhood Hits	6
SwissProt Accessions	O75339, Q6UW99, Q8IYI5	Gene names	CILP
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) (Cartilage intermediate-layer protein) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

NCOR2_HUMAN
NC score	0.019459 (rank : 20)	θ value	0.813845 (rank : 14)
Query Neighborhood Hits	47	Target Neighborhood Hits	870	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

STUB1_HUMAN
NC score	0.018343 (rank : 21)	θ value	6.88961 (rank : 37)
Query Neighborhood Hits	47	Target Neighborhood Hits	99	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UNE7, O60526, Q969U2, Q9HBT1	Gene names	STUB1, CHIP
Domain Architecture	No domain graphic available
Description	STIP1 homology and U box-containing protein 1 (EC 6.3.2.-) (STIP1 homology and U-box-containing protein 1) (Carboxy terminus of Hsp70- interacting protein) (E3 ubiquitin protein ligase CHIP) (CLL- associated antigen KW-8) (Antigen NY-CO-7).

UBP31_HUMAN
NC score	0.015796 (rank : 22)	θ value	1.38821 (rank : 18)
Query Neighborhood Hits	47	Target Neighborhood Hits	293	Shared Neighborhood Hits	5
SwissProt Accessions	Q70CQ4, Q6AW97, Q6ZTC0, Q6ZTN2, Q9ULL7	Gene names	USP31, KIAA1203
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 31 (EC 3.1.2.15) (Ubiquitin thioesterase 31) (Ubiquitin-specific-processing protease 31) (Deubiquitinating enzyme 31).

CA103_HUMAN
NC score	0.015336 (rank : 23)	θ value	6.88961 (rank : 30)
Query Neighborhood Hits	47	Target Neighborhood Hits	82	Shared Neighborhood Hits	4
SwissProt Accessions	Q5T3J3, Q86XS4, Q8N3B6, Q96HT4, Q9NUM5, Q9NV32	Gene names	C1orf103, RIF1
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf103 (Receptor-interacting factor 1).

AMOT_HUMAN
NC score	0.014141 (rank : 24)	θ value	1.81305 (rank : 19)
Query Neighborhood Hits	47	Target Neighborhood Hits	712	Shared Neighborhood Hits	4
SwissProt Accessions	Q4VCS5, Q504X5, Q9HD27, Q9UPT1	Gene names	AMOT, KIAA1071
Domain Architecture	No domain graphic available
Description	Angiomotin.

QORX_HUMAN
NC score	0.013775 (rank : 25)	θ value	8.99809 (rank : 46)
Query Neighborhood Hits	47	Target Neighborhood Hits	35	Shared Neighborhood Hits	4
SwissProt Accessions	Q53FA7, O14679, O14685, Q38G78, Q6JLE7, Q9BWB8	Gene names	TP53I3, PIG3
Domain Architecture	No domain graphic available
Description	Putative quinone oxidoreductase (EC 1.-.-.-) (Tumor protein p53- inducible protein 3) (p53-induced protein 3).

ZF106_HUMAN
NC score	0.012935 (rank : 26)	θ value	3.0926 (rank : 22)
Query Neighborhood Hits	47	Target Neighborhood Hits	470	Shared Neighborhood Hits	9
SwissProt Accessions	Q9H2Y7, Q6NSD9, Q6PEK1, Q86T43, Q86T45, Q86T50, Q86T58, Q86TA9, Q96M37, Q9H7B8	Gene names	ZFP106, ZNF474
Domain Architecture	No domain graphic available
Description	Zinc finger protein 106 homolog (Zfp-106) (Zinc finger protein 474).

CILP1_MOUSE
NC score	0.012875 (rank : 27)	θ value	8.99809 (rank : 40)
Query Neighborhood Hits	47	Target Neighborhood Hits	282	Shared Neighborhood Hits	6
SwissProt Accessions	Q66K08, Q7TSS0, Q7TSS1, Q8BV01	Gene names	Cilp
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

TOM70_HUMAN
NC score	0.011656 (rank : 28)	θ value	6.88961 (rank : 38)
Query Neighborhood Hits	47	Target Neighborhood Hits	127	Shared Neighborhood Hits	5
SwissProt Accessions	O94826	Gene names	TOMM70A, KIAA0719
Domain Architecture
Description	Mitochondrial precursor proteins import receptor (Translocase of outer membrane TOM70).

DTX2_MOUSE
NC score	0.010996 (rank : 29)	θ value	6.88961 (rank : 32)
Query Neighborhood Hits	47	Target Neighborhood Hits	76	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R3P2, Q9CZV3, Q9ER07, Q9ER08	Gene names	Dtx2
Domain Architecture
Description	Protein deltex-2 (Deltex-2) (Deltex2) (mDTX2).

CSPG4_HUMAN
NC score	0.010935 (rank : 30)	θ value	5.27518 (rank : 26)
Query Neighborhood Hits	47	Target Neighborhood Hits	112	Shared Neighborhood Hits	3
SwissProt Accessions	Q6UVK1, Q92675	Gene names	CSPG4, MCSP
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 4 precursor (Chondroitin sulfate proteoglycan NG2) (Melanoma chondroitin sulfate proteoglycan) (Melanoma-associated chondroitin sulfate proteoglycan).

PLCG_HUMAN
NC score	0.008566 (rank : 31)	θ value	8.99809 (rank : 45)
Query Neighborhood Hits	47	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	Q643R3, O43412, Q7Z4P4, Q8IUL7, Q8TB38	Gene names	AGPAT7, AYTL3
Domain Architecture	No domain graphic available
Description	1-acyl-sn-glycerol-3-phosphate acyltransferase eta (EC 2.3.1.51) (1- AGP acyltransferase 7) (1-AGPAT 7) (Lysophosphatidic acid acyltransferase-eta) (LPAAT-eta) (Acyltransferase-like 3).

CYR61_MOUSE
NC score	0.008525 (rank : 32)	θ value	6.88961 (rank : 31)
Query Neighborhood Hits	47	Target Neighborhood Hits	156	Shared Neighborhood Hits	4
SwissProt Accessions	P18406	Gene names	Cyr61, Ccn1, Igfbp10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (3CH61).

PEX6_MOUSE
NC score	0.007104 (rank : 33)	θ value	5.27518 (rank : 27)
Query Neighborhood Hits	47	Target Neighborhood Hits	94	Shared Neighborhood Hits	4
SwissProt Accessions	Q99LC9, Q6YNQ9	Gene names	Pex6
Domain Architecture	No domain graphic available
Description	Peroxisome assembly factor 2 (PAF-2) (Peroxisomal-type ATPase 1) (Peroxin-6) (Peroxisomal biogenesis factor 6).

MGR7_MOUSE
NC score	0.006757 (rank : 34)	θ value	6.88961 (rank : 34)
Query Neighborhood Hits	47	Target Neighborhood Hits	53	Shared Neighborhood Hits	4
SwissProt Accessions	Q68ED2	Gene names	Grm7, Gprc1g, Mglur7
Domain Architecture	No domain graphic available
Description	Metabotropic glutamate receptor 7 precursor (mGluR7).

MGR7_HUMAN
NC score	0.006752 (rank : 35)	θ value	6.88961 (rank : 33)
Query Neighborhood Hits	47	Target Neighborhood Hits	52	Shared Neighborhood Hits	4
SwissProt Accessions	Q14831, Q8NFS2, Q8NFS3, Q8NFS4	Gene names	GRM7, GPRC1G, MGLUR7
Domain Architecture
Description	Metabotropic glutamate receptor 7 precursor (mGluR7).

PTPRM_HUMAN
NC score	0.005983 (rank : 36)	θ value	4.03905 (rank : 24)
Query Neighborhood Hits	47	Target Neighborhood Hits	244	Shared Neighborhood Hits	5
SwissProt Accessions	P28827	Gene names	PTPRM, PTPRL1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

MUC5B_HUMAN
NC score	0.005178 (rank : 37)	θ value	8.99809 (rank : 42)
Query Neighborhood Hits	47	Target Neighborhood Hits	1020	Shared Neighborhood Hits	13
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

CBP_HUMAN
NC score	0.004936 (rank : 38)	θ value	8.99809 (rank : 39)
Query Neighborhood Hits	47	Target Neighborhood Hits	941	Shared Neighborhood Hits	8
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

PTPRM_MOUSE
NC score	0.004926 (rank : 39)	θ value	6.88961 (rank : 35)
Query Neighborhood Hits	47	Target Neighborhood Hits	238	Shared Neighborhood Hits	5
SwissProt Accessions	P28828	Gene names	Ptprm
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

KLF12_MOUSE
NC score	0.003995 (rank : 40)	θ value	2.36792 (rank : 21)
Query Neighborhood Hits	47	Target Neighborhood Hits	721	Shared Neighborhood Hits	8
SwissProt Accessions	O35738	Gene names	Klf12, Ap2rep
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 12 (Transcriptional repressor AP-2rep).

PGCB_HUMAN
NC score	0.003291 (rank : 41)	θ value	8.99809 (rank : 44)
Query Neighborhood Hits	47	Target Neighborhood Hits	478	Shared Neighborhood Hits	4
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

MTF1_HUMAN
NC score	0.003107 (rank : 42)	θ value	1.38821 (rank : 17)
Query Neighborhood Hits	47	Target Neighborhood Hits	814	Shared Neighborhood Hits	8
SwissProt Accessions	Q14872, Q96CB1	Gene names	MTF1
Domain Architecture	No domain graphic available
Description	Metal-regulatory transcription factor 1 (Transcription factor MTF-1) (MRE-binding transcription factor).

KLF12_HUMAN
NC score	0.003098 (rank : 43)	θ value	4.03905 (rank : 23)
Query Neighborhood Hits	47	Target Neighborhood Hits	717	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y4X4, Q5VZM7, Q9UHZ0	Gene names	KLF12, AP2REP
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 12 (Transcriptional repressor AP-2rep).

TMPS9_MOUSE
NC score	0.001389 (rank : 44)	θ value	8.99809 (rank : 47)
Query Neighborhood Hits	47	Target Neighborhood Hits	296	Shared Neighborhood Hits	5
SwissProt Accessions	P69525	Gene names	Tmprss9
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 9 (EC 3.4.21.-) (Polyserase-1) (Polyserine protease 1) (Polyserase-I) [Contains: Serase-1; Serase-2; Serase-3].

TF3A_HUMAN
NC score	0.001091 (rank : 45)	θ value	5.27518 (rank : 28)
Query Neighborhood Hits	47	Target Neighborhood Hits	726	Shared Neighborhood Hits	8
SwissProt Accessions	Q92664, Q12963, Q13097	Gene names	GTF3A
Domain Architecture	No domain graphic available
Description	Transcription factor IIIA (Factor A) (TFIIIA).

MTF1_MOUSE
NC score	0.000886 (rank : 46)	θ value	8.99809 (rank : 41)
Query Neighborhood Hits	47	Target Neighborhood Hits	785	Shared Neighborhood Hits	8
SwissProt Accessions	Q07243	Gene names	Mtf1, Mtf-1
Domain Architecture	No domain graphic available
Description	Metal-regulatory transcription factor 1 (Transcription factor MTF-1) (MRE-binding transcription factor).

MYLK_HUMAN
NC score	-0.001923 (rank : 47)	θ value	8.99809 (rank : 43)
Query Neighborhood Hits	47	Target Neighborhood Hits	1328	Shared Neighborhood Hits	8
SwissProt Accessions	Q15746, O95796, O95797, O95798, O95799, Q14844, Q16794, Q5MY99, Q5MYA0, Q7Z4J0, Q9C0L5, Q9UBG5, Q9UIT9	Gene names	MYLK, MLCK
Domain Architecture
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).