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Network neighborhood for query Sequence : SPAST_MOUSE

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SPAST_MOUSE
SwissProt Accessions	Q9QYY8, Q6ZPY6, Q80VE0, Q9CVK0	Gene names	Spast, Kiaa1083, Spg4
Domain Architecture	No domain graphic available
Description	Spastin.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SPAST_HUMAN
θ value	0 (rank : 1)	NC score	0.997290 (rank : 2)
Query Neighborhood Hits	138	Target Neighborhood Hits	100	Shared Neighborhood Hits	89
SwissProt Accessions	Q9UBP0, Q9UPR9	Gene names	SPAST, KIAA1083, SPG4
Domain Architecture
Description	Spastin.

SPAST_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	138	Target Neighborhood Hits	138	Shared Neighborhood Hits	138
SwissProt Accessions	Q9QYY8, Q6ZPY6, Q80VE0, Q9CVK0	Gene names	Spast, Kiaa1083, Spg4
Domain Architecture	No domain graphic available
Description	Spastin.

FIGN_MOUSE
θ value	6.76295e-64 (rank : 3)	NC score	0.939964 (rank : 13)
Query Neighborhood Hits	138	Target Neighborhood Hits	165	Shared Neighborhood Hits	57
SwissProt Accessions	Q9ERZ6, Q3TPB0, Q3UP57, Q6PCM0	Gene names	Fign
Domain Architecture	No domain graphic available
Description	Fidgetin.

KATL1_HUMAN
θ value	1.50663e-63 (rank : 4)	NC score	0.962697 (rank : 4)
Query Neighborhood Hits	138	Target Neighborhood Hits	80	Shared Neighborhood Hits	63
SwissProt Accessions	Q9BW62	Gene names	KATNAL1
Domain Architecture	No domain graphic available
Description	Katanin p60 ATPase-containing subunit A-like 1 (EC 3.6.4.3) (Katanin p60 subunit A-like 1) (p60 katanin-like 1).

FIGN_HUMAN
θ value	2.56992e-63 (rank : 5)	NC score	0.935643 (rank : 14)
Query Neighborhood Hits	138	Target Neighborhood Hits	176	Shared Neighborhood Hits	57
SwissProt Accessions	Q5HY92, Q9H6M5, Q9NVZ9	Gene names	FIGN
Domain Architecture	No domain graphic available
Description	Fidgetin.

KATL1_MOUSE
θ value	5.7252e-63 (rank : 6)	NC score	0.963025 (rank : 3)
Query Neighborhood Hits	138	Target Neighborhood Hits	77	Shared Neighborhood Hits	63
SwissProt Accessions	Q8K0T4	Gene names	Katnal1
Domain Architecture	No domain graphic available
Description	Katanin p60 ATPase-containing subunit A-like 1 (EC 3.6.4.3) (Katanin p60 subunit A-like 1) (p60 katanin-like 1).

KTNA1_HUMAN
θ value	7.47731e-63 (rank : 7)	NC score	0.961469 (rank : 5)
Query Neighborhood Hits	138	Target Neighborhood Hits	117	Shared Neighborhood Hits	65
SwissProt Accessions	O75449, Q5TFA8, Q5TFA9, Q86VN2, Q9NU52	Gene names	KATNA1
Domain Architecture	No domain graphic available
Description	Katanin p60 ATPase-containing subunit A1 (EC 3.6.4.3) (Katanin p60 subunit A1) (p60 katanin).

KTNA1_MOUSE
θ value	6.32992e-62 (rank : 8)	NC score	0.959766 (rank : 6)
Query Neighborhood Hits	138	Target Neighborhood Hits	123	Shared Neighborhood Hits	67
SwissProt Accessions	Q9WV86	Gene names	Katna1
Domain Architecture	No domain graphic available
Description	Katanin p60 ATPase-containing subunit A1 (EC 3.6.4.3) (Katanin p60 subunit A1) (p60 katanin) (Lipotransin).

VPS4B_HUMAN
θ value	8.26713e-62 (rank : 9)	NC score	0.957480 (rank : 9)
Query Neighborhood Hits	138	Target Neighborhood Hits	87	Shared Neighborhood Hits	62
SwissProt Accessions	O75351, Q9GZS7	Gene names	VPS4B, SKD1, VPS42
Domain Architecture
Description	Vacuolar protein sorting-associating protein 4B (Protein SKD1).

VPS4B_MOUSE
θ value	1.41016e-61 (rank : 10)	NC score	0.956956 (rank : 10)
Query Neighborhood Hits	138	Target Neighborhood Hits	86	Shared Neighborhood Hits	61
SwissProt Accessions	P46467, Q91W22, Q9R1C9	Gene names	Vps4b, Skd1
Domain Architecture
Description	Vacuolar protein sorting-associating protein 4B (Protein SKD1).

VPS4A_HUMAN
θ value	1.31987e-59 (rank : 11)	NC score	0.953887 (rank : 11)
Query Neighborhood Hits	138	Target Neighborhood Hits	95	Shared Neighborhood Hits	62
SwissProt Accessions	Q9UN37, Q8TF07, Q9UI03, Q9Y582	Gene names	VPS4A, VPS4
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associating protein 4A (SKD2 protein) (hVPS4) (VPS4-1).

VPS4A_MOUSE
θ value	1.31987e-59 (rank : 12)	NC score	0.953855 (rank : 12)
Query Neighborhood Hits	138	Target Neighborhood Hits	94	Shared Neighborhood Hits	62
SwissProt Accessions	Q8VEJ9, Q3TXT2	Gene names	Vps4a
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associating protein 4A.

ATAD1_HUMAN
θ value	2.3352e-48 (rank : 13)	NC score	0.958906 (rank : 7)
Query Neighborhood Hits	138	Target Neighborhood Hits	75	Shared Neighborhood Hits	61
SwissProt Accessions	Q8NBU5, Q6P4B9, Q8N3G1, Q8WYR9, Q969Y3	Gene names	ATAD1
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 1.

ATAD1_MOUSE
θ value	2.3352e-48 (rank : 14)	NC score	0.958906 (rank : 8)
Query Neighborhood Hits	138	Target Neighborhood Hits	75	Shared Neighborhood Hits	61
SwissProt Accessions	Q9D5T0, Q3U8V2, Q9D7A4	Gene names	Atad1
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 1.

TERA_HUMAN
θ value	3.16345e-37 (rank : 15)	NC score	0.920724 (rank : 17)
Query Neighborhood Hits	138	Target Neighborhood Hits	76	Shared Neighborhood Hits	62
SwissProt Accessions	P55072, Q969G7	Gene names	VCP
Domain Architecture
Description	Transitional endoplasmic reticulum ATPase (TER ATPase) (15S Mg(2+)- ATPase p97 subunit) (Valosin-containing protein) (VCP).

TERA_MOUSE
θ value	3.16345e-37 (rank : 16)	NC score	0.920685 (rank : 18)
Query Neighborhood Hits	138	Target Neighborhood Hits	76	Shared Neighborhood Hits	62
SwissProt Accessions	Q01853	Gene names	Vcp
Domain Architecture
Description	Transitional endoplasmic reticulum ATPase (TER ATPase) (15S Mg(2+)- ATPase p97 subunit) (Valosin-containing protein) (VCP).

NVL_HUMAN
θ value	2.67802e-36 (rank : 17)	NC score	0.913628 (rank : 27)
Query Neighborhood Hits	138	Target Neighborhood Hits	112	Shared Neighborhood Hits	65
SwissProt Accessions	O15381, Q96EM7	Gene names	NVL
Domain Architecture
Description	Nuclear valosin-containing protein-like (Nuclear VCP-like protein) (NVLp).

NVL_MOUSE
θ value	5.96599e-36 (rank : 18)	NC score	0.913965 (rank : 26)
Query Neighborhood Hits	138	Target Neighborhood Hits	110	Shared Neighborhood Hits	65
SwissProt Accessions	Q9DBY8, Q3USC4, Q8BW27, Q8K2B5	Gene names	Nvl
Domain Architecture
Description	Nuclear valosin-containing protein-like (Nuclear VCP-like protein) (NVLp).

PRS8_HUMAN
θ value	1.12514e-34 (rank : 19)	NC score	0.919217 (rank : 19)
Query Neighborhood Hits	138	Target Neighborhood Hits	117	Shared Neighborhood Hits	61
SwissProt Accessions	P62195, O35051, O43208, P47210, P52915, P52916	Gene names	PSMC5, SUG1
Domain Architecture
Description	26S protease regulatory subunit 8 (Proteasome 26S subunit ATPase 5) (Proteasome subunit p45) (p45/SUG) (Thyroid hormone receptor- interacting protein 1) (TRIP1).

PRS8_MOUSE
θ value	1.12514e-34 (rank : 20)	NC score	0.919217 (rank : 20)
Query Neighborhood Hits	138	Target Neighborhood Hits	117	Shared Neighborhood Hits	61
SwissProt Accessions	P62196, O35051, P47210, P52915, P52916, Q3UL51, Q9CWN5	Gene names	Psmc5, Sug1
Domain Architecture
Description	26S protease regulatory subunit 8 (Proteasome 26S subunit ATPase 5) (Proteasome subunit p45) (p45/SUG) (mSUG1).

PRS10_HUMAN
θ value	2.50655e-34 (rank : 21)	NC score	0.921638 (rank : 15)
Query Neighborhood Hits	138	Target Neighborhood Hits	95	Shared Neighborhood Hits	61
SwissProt Accessions	P62333, P49719, Q6IBU3, Q92524	Gene names	PSMC6, SUG2
Domain Architecture
Description	26S protease regulatory subunit S10B (Proteasome subunit p42) (Proteasome 26S subunit ATPase 6).

PRS10_MOUSE
θ value	2.50655e-34 (rank : 22)	NC score	0.921638 (rank : 16)
Query Neighborhood Hits	138	Target Neighborhood Hits	95	Shared Neighborhood Hits	61
SwissProt Accessions	P62334, P49719, Q3TKK1, Q810A6, Q92524, Q9CXH9	Gene names	Psmc6, Sug2
Domain Architecture
Description	26S protease regulatory subunit S10B (Proteasome subunit p42) (Proteasome 26S subunit ATPase 6).

PRS4_HUMAN
θ value	2.12192e-33 (rank : 23)	NC score	0.916139 (rank : 23)
Query Neighborhood Hits	138	Target Neighborhood Hits	84	Shared Neighborhood Hits	62
SwissProt Accessions	P62191, P49014, Q03527, Q6IAW0, Q96AZ3	Gene names	PSMC1
Domain Architecture
Description	26S protease regulatory subunit 4 (P26s4) (Proteasome 26S subunit ATPase 1).

PRS4_MOUSE
θ value	2.12192e-33 (rank : 24)	NC score	0.916139 (rank : 24)
Query Neighborhood Hits	138	Target Neighborhood Hits	84	Shared Neighborhood Hits	62
SwissProt Accessions	P62192, P49014, Q03527, Q96AZ3	Gene names	Psmc1
Domain Architecture
Description	26S protease regulatory subunit 4 (P26s4) (Proteasome 26S subunit ATPase 1).

PRS6A_HUMAN
θ value	3.61944e-33 (rank : 25)	NC score	0.917300 (rank : 22)
Query Neighborhood Hits	138	Target Neighborhood Hits	87	Shared Neighborhood Hits	57
SwissProt Accessions	P17980, Q96HD3	Gene names	PSMC3, TBP1
Domain Architecture
Description	26S protease regulatory subunit 6A (Proteasome 26S subunit ATPase 3) (TAT-binding protein 1) (TBP-1) (Proteasome subunit P50).

PRS6A_MOUSE
θ value	4.72714e-33 (rank : 26)	NC score	0.917412 (rank : 21)
Query Neighborhood Hits	138	Target Neighborhood Hits	85	Shared Neighborhood Hits	57
SwissProt Accessions	O88685	Gene names	Psmc3, Tbp1
Domain Architecture
Description	26S protease regulatory subunit 6A (Proteasome 26S subunit ATPase 3) (TAT-binding protein 1) (TBP-1).

ATAD2_MOUSE
θ value	1.16434e-31 (rank : 27)	NC score	0.866736 (rank : 41)
Query Neighborhood Hits	138	Target Neighborhood Hits	167	Shared Neighborhood Hits	60
SwissProt Accessions	Q8CDM1	Gene names	Atad2
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 2.

ATAD2_HUMAN
θ value	1.52067e-31 (rank : 28)	NC score	0.849238 (rank : 43)
Query Neighborhood Hits	138	Target Neighborhood Hits	322	Shared Neighborhood Hits	61
SwissProt Accessions	Q6PL18, Q658P2, Q68CQ0, Q6PJV6, Q8N890, Q9UHS5	Gene names	ATAD2
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 2.

PEX6_MOUSE
θ value	3.3877e-31 (rank : 29)	NC score	0.904334 (rank : 33)
Query Neighborhood Hits	138	Target Neighborhood Hits	94	Shared Neighborhood Hits	60
SwissProt Accessions	Q99LC9, Q6YNQ9	Gene names	Pex6
Domain Architecture	No domain graphic available
Description	Peroxisome assembly factor 2 (PAF-2) (Peroxisomal-type ATPase 1) (Peroxin-6) (Peroxisomal biogenesis factor 6).

PEX1_HUMAN
θ value	4.42448e-31 (rank : 30)	NC score	0.914109 (rank : 25)
Query Neighborhood Hits	138	Target Neighborhood Hits	98	Shared Neighborhood Hits	60
SwissProt Accessions	O43933, Q96S71, Q96S72, Q96S73, Q99994	Gene names	PEX1
Domain Architecture
Description	Peroxisome biogenesis factor 1 (Peroxin-1) (Peroxisome biogenesis disorder protein 1).

PEX6_HUMAN
θ value	9.8567e-31 (rank : 31)	NC score	0.904410 (rank : 32)
Query Neighborhood Hits	138	Target Neighborhood Hits	99	Shared Neighborhood Hits	61
SwissProt Accessions	Q13608, Q8WYQ2, Q99476	Gene names	PEX6, PXAAA1
Domain Architecture
Description	Peroxisome assembly factor 2 (PAF-2) (Peroxisomal-type ATPase 1) (Peroxin-6) (Peroxisomal biogenesis factor 6).

AFG31_MOUSE
θ value	1.28732e-30 (rank : 32)	NC score	0.893989 (rank : 37)
Query Neighborhood Hits	138	Target Neighborhood Hits	74	Shared Neighborhood Hits	63
SwissProt Accessions	Q920A7	Gene names	Afg3l1
Domain Architecture
Description	AFG3-like protein 1 (EC 3.4.24.-).

AFG32_HUMAN
θ value	1.6813e-30 (rank : 33)	NC score	0.889516 (rank : 39)
Query Neighborhood Hits	138	Target Neighborhood Hits	72	Shared Neighborhood Hits	63
SwissProt Accessions	Q9Y4W6	Gene names	AFG3L2
Domain Architecture
Description	AFG3-like protein 2 (EC 3.4.24.-) (Paraplegin-like protein).

AFG32_MOUSE
θ value	1.6813e-30 (rank : 34)	NC score	0.889543 (rank : 38)
Query Neighborhood Hits	138	Target Neighborhood Hits	73	Shared Neighborhood Hits	63
SwissProt Accessions	Q8JZQ2	Gene names	Afg3l2
Domain Architecture	No domain graphic available
Description	AFG3-like protein 2 (EC 3.4.24.-).

PRS6B_HUMAN
θ value	4.89182e-30 (rank : 35)	NC score	0.912149 (rank : 28)
Query Neighborhood Hits	138	Target Neighborhood Hits	85	Shared Neighborhood Hits	58
SwissProt Accessions	P43686, Q96FV5, Q9UBM3, Q9UEX3	Gene names	PSMC4, TBP7
Domain Architecture
Description	26S protease regulatory subunit 6B (Proteasome 26S subunit ATPase 4) (MIP224) (MB67-interacting protein) (TAT-binding protein 7) (TBP-7).

PRS6B_MOUSE
θ value	2.42779e-29 (rank : 36)	NC score	0.910988 (rank : 29)
Query Neighborhood Hits	138	Target Neighborhood Hits	89	Shared Neighborhood Hits	59
SwissProt Accessions	P54775	Gene names	Psmc4, Tbp7
Domain Architecture
Description	26S protease regulatory subunit 6B (Proteasome 26S subunit ATPase 4) (MIP224) (MB67-interacting protein) (TAT-binding protein 7) (TBP-7) (CIP21).

YMEL1_MOUSE
θ value	3.17079e-29 (rank : 37)	NC score	0.897238 (rank : 34)
Query Neighborhood Hits	138	Target Neighborhood Hits	76	Shared Neighborhood Hits	57
SwissProt Accessions	O88967, Q7TNN5	Gene names	Yme1l1
Domain Architecture
Description	ATP-dependent metalloprotease YME1L1 (EC 3.4.24.-) (YME1-like protein 1) (ATP-dependent metalloprotease FtsH1).

PRS7_HUMAN
θ value	7.06379e-29 (rank : 38)	NC score	0.910334 (rank : 30)
Query Neighborhood Hits	138	Target Neighborhood Hits	66	Shared Neighborhood Hits	59
SwissProt Accessions	P35998	Gene names	PSMC2, MSS1
Domain Architecture
Description	26S protease regulatory subunit 7 (Proteasome 26S subunit ATPase 2) (Protein MSS1).

PRS7_MOUSE
θ value	7.06379e-29 (rank : 39)	NC score	0.910326 (rank : 31)
Query Neighborhood Hits	138	Target Neighborhood Hits	67	Shared Neighborhood Hits	59
SwissProt Accessions	P46471, O08531, Q3TGX5, Q9DBA1	Gene names	Psmc2, Mss1
Domain Architecture
Description	26S protease regulatory subunit 7 (Proteasome 26S subunit ATPase 2) (Protein MSS1).

YMEL1_HUMAN
θ value	1.33217e-27 (rank : 40)	NC score	0.894178 (rank : 36)
Query Neighborhood Hits	138	Target Neighborhood Hits	73	Shared Neighborhood Hits	57
SwissProt Accessions	Q96TA2, Q9H1Q0, Q9UMR9	Gene names	YME1L1, FTSH1, YME1L
Domain Architecture
Description	ATP-dependent metalloprotease YME1L1 (EC 3.4.24.-) (YME1-like protein 1) (ATP-dependent metalloprotease FtsH1) (Meg-4) (Presenilin- associated metalloprotease) (PAMP).

SPG7_HUMAN
θ value	1.12775e-26 (rank : 41)	NC score	0.894784 (rank : 35)
Query Neighborhood Hits	138	Target Neighborhood Hits	71	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UQ90, O75756, Q96IB0	Gene names	SPG7, CAR, CMAR, PGN
Domain Architecture
Description	Paraplegin (EC 3.4.24.-) (Spastic paraplegia protein 7).

NSF_HUMAN
θ value	2.27762e-19 (rank : 42)	NC score	0.866928 (rank : 40)
Query Neighborhood Hits	138	Target Neighborhood Hits	74	Shared Neighborhood Hits	63
SwissProt Accessions	P46459, Q9UKZ2	Gene names	NSF
Domain Architecture
Description	Vesicle-fusing ATPase (EC 3.6.4.6) (Vesicular-fusion protein NSF) (N- ethylmaleimide sensitive fusion protein) (NEM-sensitive fusion protein).

NSF_MOUSE
θ value	2.27762e-19 (rank : 43)	NC score	0.866570 (rank : 42)
Query Neighborhood Hits	138	Target Neighborhood Hits	73	Shared Neighborhood Hits	60
SwissProt Accessions	P46460	Gene names	Nsf, Skd2
Domain Architecture
Description	Vesicle-fusing ATPase (EC 3.6.4.6) (Vesicular-fusion protein NSF) (N- ethylmaleimide sensitive fusion protein) (NEM-sensitive fusion protein) (SKD2 protein).

ATD3A_HUMAN
θ value	5.08577e-11 (rank : 44)	NC score	0.650376 (rank : 46)
Query Neighborhood Hits	138	Target Neighborhood Hits	248	Shared Neighborhood Hits	64
SwissProt Accessions	Q9NVI7, Q8N275, Q96A50	Gene names	ATAD3A
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 3A.

ATD3B_HUMAN
θ value	5.62301e-10 (rank : 45)	NC score	0.631425 (rank : 47)
Query Neighborhood Hits	138	Target Neighborhood Hits	340	Shared Neighborhood Hits	65
SwissProt Accessions	Q5T9A4, Q6ZRB5, Q9BUK4, Q9ULE7	Gene names	ATAD3B, KIAA1273
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 3B.

ATAD3_MOUSE
θ value	1.63604e-09 (rank : 46)	NC score	0.623862 (rank : 48)
Query Neighborhood Hits	138	Target Neighborhood Hits	326	Shared Neighborhood Hits	67
SwissProt Accessions	Q925I1, Q3UE74, Q69ZM7, Q8C6C6	Gene names	Atad3, Atad3a, Kiaa1273
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 3 (AAA-ATPase TOB3).

SPG20_HUMAN
θ value	3.08544e-08 (rank : 47)	NC score	0.152360 (rank : 59)
Query Neighborhood Hits	138	Target Neighborhood Hits	28	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N0X7, O60349, Q86Y67, Q9H1T2, Q9H1T3	Gene names	SPG20, KIAA0610, TAHCCP1
Domain Architecture	No domain graphic available
Description	Spartin (Trans-activated by hepatitis C virus core protein 1).

SPG20_MOUSE
θ value	4.0297e-08 (rank : 48)	NC score	0.152692 (rank : 58)
Query Neighborhood Hits	138	Target Neighborhood Hits	33	Shared Neighborhood Hits	5
SwissProt Accessions	Q8R1X6, Q6ZQ87, Q8BJD3, Q8BM37, Q8BZ63	Gene names	Spg20, Kiaa0610
Domain Architecture	No domain graphic available
Description	Spartin.

TRP13_HUMAN
θ value	9.92553e-07 (rank : 49)	NC score	0.701789 (rank : 45)
Query Neighborhood Hits	138	Target Neighborhood Hits	81	Shared Neighborhood Hits	56
SwissProt Accessions	Q15645, O15324	Gene names	TRIP13
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 13 (Thyroid hormone receptor interactor 13) (Trip-13) (Human papillomavirus type 16 E1 protein- binding protein) (HPV16 E1 protein-binding protein) (16E1-BP).

TRP13_MOUSE
θ value	9.92553e-07 (rank : 50)	NC score	0.705035 (rank : 44)
Query Neighborhood Hits	138	Target Neighborhood Hits	81	Shared Neighborhood Hits	56
SwissProt Accessions	Q3UA06, Q3UQG6, Q9CWW8	Gene names	Trip13
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 13 (Thyroid hormone receptor interactor 13) (Trip-13).

LONM_HUMAN
θ value	0.00035302 (rank : 51)	NC score	0.435653 (rank : 51)
Query Neighborhood Hits	138	Target Neighborhood Hits	130	Shared Neighborhood Hits	57
SwissProt Accessions	P36776, P36777, Q9UQ95	Gene names	PRSS15
Domain Architecture
Description	Lon protease homolog, mitochondrial precursor (EC 3.4.21.-) (Lon protease-like protein) (LONP) (LONHs).

BCS1_HUMAN
θ value	0.00134147 (rank : 52)	NC score	0.602644 (rank : 49)
Query Neighborhood Hits	138	Target Neighborhood Hits	61	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Y276, Q7Z2V7	Gene names	BCS1L, BCS1
Domain Architecture
Description	Mitochondrial chaperone BCS1 (BCS1-like protein) (H-BCS1).

CLPX_HUMAN
θ value	0.00134147 (rank : 53)	NC score	0.429934 (rank : 52)
Query Neighborhood Hits	138	Target Neighborhood Hits	72	Shared Neighborhood Hits	51
SwissProt Accessions	O76031, Q9H4D9	Gene names	CLPX
Domain Architecture
Description	ATP-dependent Clp protease ATP-binding subunit ClpX-like, mitochondrial precursor.

CLPX_MOUSE
θ value	0.00134147 (rank : 54)	NC score	0.426891 (rank : 53)
Query Neighborhood Hits	138	Target Neighborhood Hits	73	Shared Neighborhood Hits	51
SwissProt Accessions	Q9JHS4, Q9WVD1	Gene names	Clpx
Domain Architecture
Description	ATP-dependent Clp protease ATP-binding subunit ClpX-like, mitochondrial precursor.

BCS1_MOUSE
θ value	0.00665767 (rank : 55)	NC score	0.587966 (rank : 50)
Query Neighborhood Hits	138	Target Neighborhood Hits	64	Shared Neighborhood Hits	50
SwissProt Accessions	Q9CZP5	Gene names	Bcs1l
Domain Architecture
Description	Mitochondrial chaperone BCS1 (BCS1-like protein).

RUVB1_HUMAN
θ value	0.00665767 (rank : 56)	NC score	0.334037 (rank : 54)
Query Neighborhood Hits	138	Target Neighborhood Hits	78	Shared Neighborhood Hits	57
SwissProt Accessions	Q9Y265, Q9BSX9	Gene names	RUVBL1, NMP238, TIP49, TIP49A
Domain Architecture
Description	RuvB-like 1 (EC 3.6.1.-) (49 kDa TATA box-binding protein-interacting protein) (49 kDa TBP-interacting protein) (TIP49a) (Pontin 52) (Nuclear matrix protein 238) (NMP 238) (54 kDa erythrocyte cytosolic protein) (ECP-54) (TIP60-associated protein 54-alpha) (TAP54-alpha).

RUVB1_MOUSE
θ value	0.00665767 (rank : 57)	NC score	0.333997 (rank : 55)
Query Neighborhood Hits	138	Target Neighborhood Hits	78	Shared Neighborhood Hits	57
SwissProt Accessions	P60122, O35753	Gene names	Ruvbl1, Tip49, Tip49a
Domain Architecture
Description	RuvB-like 1 (EC 3.6.1.-) (49 kDa TATA box-binding protein-interacting protein) (49 kDa TBP-interacting protein) (TIP49a) (Pontin 52) (DNA helicase p50).

CJ012_HUMAN
θ value	0.163984 (rank : 58)	NC score	0.034926 (rank : 73)
Query Neighborhood Hits	138	Target Neighborhood Hits	467	Shared Neighborhood Hits	18
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

SPN1_MOUSE
θ value	0.21417 (rank : 59)	NC score	0.038567 (rank : 72)
Query Neighborhood Hits	138	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	Q80W37	Gene names	Snupn, Rnut1
Domain Architecture	No domain graphic available
Description	Snurportin-1 (RNA U transporter 1).

MK15_HUMAN
θ value	0.365318 (rank : 60)	NC score	-0.002079 (rank : 140)
Query Neighborhood Hits	138	Target Neighborhood Hits	1038	Shared Neighborhood Hits	18
SwissProt Accessions	Q8TD08, Q2TCF9, Q8N362	Gene names	MAPK15, ERK8
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase 15 (EC 2.7.11.24) (Extracellular signal-regulated kinase 8).

SRRM1_MOUSE
θ value	0.365318 (rank : 61)	NC score	0.020213 (rank : 78)
Query Neighborhood Hits	138	Target Neighborhood Hits	966	Shared Neighborhood Hits	23
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

WRIP1_HUMAN
θ value	0.365318 (rank : 62)	NC score	0.231533 (rank : 56)
Query Neighborhood Hits	138	Target Neighborhood Hits	100	Shared Neighborhood Hits	52
SwissProt Accessions	Q96S55, Q53EP6, Q59ET8, Q5W0E2, Q5W0E4, Q8WV26, Q9H681, Q9NRJ6	Gene names	WRNIP1, WHIP
Domain Architecture	No domain graphic available
Description	ATPase WRNIP1 (Werner helicase-interacting protein 1).

OGFR_HUMAN
θ value	0.62314 (rank : 63)	NC score	0.010411 (rank : 100)
Query Neighborhood Hits	138	Target Neighborhood Hits	1582	Shared Neighborhood Hits	40
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

ST5_MOUSE
θ value	0.62314 (rank : 64)	NC score	0.014855 (rank : 83)
Query Neighborhood Hits	138	Target Neighborhood Hits	126	Shared Neighborhood Hits	7
SwissProt Accessions	Q924W7, Q78H54, Q8K2P3, Q924W8	Gene names	St5, Dennd2b
Domain Architecture	No domain graphic available
Description	Suppression of tumorigenicity 5 (DENN domain-containing protein 2B).

WRIP1_MOUSE
θ value	0.62314 (rank : 65)	NC score	0.228754 (rank : 57)
Query Neighborhood Hits	138	Target Neighborhood Hits	93	Shared Neighborhood Hits	52
SwissProt Accessions	Q91XU0, Q3TCT7, Q6PDF0, Q8BUW5, Q8BWP6, Q8BY55, Q921W3, Q9EQL3	Gene names	Wrnip1, Whip
Domain Architecture	No domain graphic available
Description	ATPase WRNIP1 (Werner helicase-interacting protein 1).

NFH_MOUSE
θ value	0.813845 (rank : 66)	NC score	0.001782 (rank : 132)
Query Neighborhood Hits	138	Target Neighborhood Hits	2247	Shared Neighborhood Hits	45
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

SRRM2_MOUSE
θ value	1.06291 (rank : 67)	NC score	0.021710 (rank : 76)
Query Neighborhood Hits	138	Target Neighborhood Hits	1470	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

ST5_HUMAN
θ value	1.06291 (rank : 68)	NC score	0.014568 (rank : 84)
Query Neighborhood Hits	138	Target Neighborhood Hits	151	Shared Neighborhood Hits	7
SwissProt Accessions	P78524, P78523, Q16492, Q7KYY2, Q7KZ12, Q8NE12, Q9BQQ6	Gene names	ST5, DENND2B, HTS1
Domain Architecture	No domain graphic available
Description	Suppression of tumorigenicity 5 (HeLa tumor suppression 1) (DENN domain-containing protein 2B).

BAT3_MOUSE
θ value	1.38821 (rank : 69)	NC score	0.018302 (rank : 80)
Query Neighborhood Hits	138	Target Neighborhood Hits	518	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

EP400_HUMAN
θ value	1.38821 (rank : 70)	NC score	0.012055 (rank : 89)
Query Neighborhood Hits	138	Target Neighborhood Hits	556	Shared Neighborhood Hits	18
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

FHOD1_MOUSE
θ value	1.38821 (rank : 71)	NC score	0.012340 (rank : 88)
Query Neighborhood Hits	138	Target Neighborhood Hits	217	Shared Neighborhood Hits	12
SwissProt Accessions	Q6P9Q4, Q8BMK2	Gene names	Fhod1, Fhos1
Domain Architecture	No domain graphic available
Description	FH1/FH2 domain-containing protein (Formin homolog overexpressed in spleen) (FHOS) (Formin homology 2 domain-containing protein 1).

ABCF1_HUMAN
θ value	1.81305 (rank : 72)	NC score	0.011825 (rank : 90)
Query Neighborhood Hits	138	Target Neighborhood Hits	343	Shared Neighborhood Hits	9
SwissProt Accessions	Q8NE71, O14897, Q69YP6	Gene names	ABCF1, ABC50
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 1 (ATP-binding cassette 50) (TNF-alpha-stimulated ABC protein).

M3K15_HUMAN
θ value	1.81305 (rank : 73)	NC score	-0.002084 (rank : 141)
Query Neighborhood Hits	138	Target Neighborhood Hits	914	Shared Neighborhood Hits	13
SwissProt Accessions	Q6ZN16, Q5JPR4, Q6ZMV3	Gene names	MAP3K15
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 15 (EC 2.7.11.25) (MAPK/ERK kinase kinase 15) (MEK kinase 15) (MEKK 15).

M3K6_HUMAN
θ value	1.81305 (rank : 74)	NC score	-0.001959 (rank : 138)
Query Neighborhood Hits	138	Target Neighborhood Hits	889	Shared Neighborhood Hits	10
SwissProt Accessions	O95382	Gene names	MAP3K6, MAPKKK6
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 6 (EC 2.7.11.25).

MAST4_HUMAN
θ value	1.81305 (rank : 75)	NC score	-0.002236 (rank : 142)
Query Neighborhood Hits	138	Target Neighborhood Hits	1804	Shared Neighborhood Hits	31
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

MKL2_HUMAN
θ value	1.81305 (rank : 76)	NC score	0.010370 (rank : 101)
Query Neighborhood Hits	138	Target Neighborhood Hits	274	Shared Neighborhood Hits	14
SwissProt Accessions	Q9ULH7, Q68CT1, Q6UB16, Q86WW2, Q8N226	Gene names	MKL2, KIAA1243, MRTFB
Domain Architecture
Description	MKL/myocardin-like protein 2 (Myocardin-related transcription factor B) (MRTF-B) (Megakaryoblastic leukemia 2).

ZDHC8_HUMAN
θ value	1.81305 (rank : 77)	NC score	0.006276 (rank : 114)
Query Neighborhood Hits	138	Target Neighborhood Hits	234	Shared Neighborhood Hits	9
SwissProt Accessions	Q9ULC8, Q6ICL1, Q6ZNF5, Q7Z6L9	Gene names	ZDHHC8, KIAA1292, ZDHHCL1, ZNF378
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC8 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 8) (DHHC-8) (Zinc finger protein 378).

ZFHX2_HUMAN
θ value	1.81305 (rank : 78)	NC score	0.004100 (rank : 123)
Query Neighborhood Hits	138	Target Neighborhood Hits	1178	Shared Neighborhood Hits	12
SwissProt Accessions	Q9C0A1	Gene names	ZFHX2, KIAA1762
Domain Architecture
Description	Zinc finger homeobox protein 2.

EP400_MOUSE
θ value	2.36792 (rank : 79)	NC score	0.009996 (rank : 102)
Query Neighborhood Hits	138	Target Neighborhood Hits	592	Shared Neighborhood Hits	16
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

FOXL1_HUMAN
θ value	2.36792 (rank : 80)	NC score	0.002446 (rank : 128)
Query Neighborhood Hits	138	Target Neighborhood Hits	114	Shared Neighborhood Hits	5
SwissProt Accessions	Q12952, Q9H242	Gene names	FOXL1, FKHL11, FREAC7
Domain Architecture
Description	Forkhead box protein L1 (Forkhead-related protein FKHL11) (Forkhead- related transcription factor 7) (FREAC-7).

HRX_HUMAN
θ value	2.36792 (rank : 81)	NC score	0.007959 (rank : 107)
Query Neighborhood Hits	138	Target Neighborhood Hits	825	Shared Neighborhood Hits	24
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

NIP30_MOUSE
θ value	2.36792 (rank : 82)	NC score	0.026730 (rank : 74)
Query Neighborhood Hits	138	Target Neighborhood Hits	76	Shared Neighborhood Hits	3
SwissProt Accessions	Q91WE2, Q8R0C9	Gene names	Nip30
Domain Architecture	No domain graphic available
Description	NEFA-interacting nuclear protein NIP30.

NSMA2_HUMAN
θ value	2.36792 (rank : 83)	NC score	0.012845 (rank : 87)
Query Neighborhood Hits	138	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NY59	Gene names	SMPD3
Domain Architecture	No domain graphic available
Description	Sphingomyelin phosphodiesterase 3 (EC 3.1.4.12) (Neutral sphingomyelinase 2) (Neutral sphingomyelinase II) (nSMase2) (nSMase- 2).

PCLO_MOUSE
θ value	2.36792 (rank : 84)	NC score	0.011162 (rank : 94)
Query Neighborhood Hits	138	Target Neighborhood Hits	2275	Shared Neighborhood Hits	41
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

YBOX2_HUMAN
θ value	2.36792 (rank : 85)	NC score	0.013052 (rank : 86)
Query Neighborhood Hits	138	Target Neighborhood Hits	50	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y2T7, Q8N4P0	Gene names	YBX2
Domain Architecture	No domain graphic available
Description	Y-box-binding protein 2 (Germ cell-specific Y-box-binding protein) (Contrin) (MSY2 homolog).

BSN_MOUSE
θ value	3.0926 (rank : 86)	NC score	0.007043 (rank : 113)
Query Neighborhood Hits	138	Target Neighborhood Hits	2057	Shared Neighborhood Hits	36
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CND1_HUMAN
θ value	3.0926 (rank : 87)	NC score	0.010499 (rank : 98)
Query Neighborhood Hits	138	Target Neighborhood Hits	37	Shared Neighborhood Hits	3
SwissProt Accessions	Q15021, Q8N6U3	Gene names	NCAPD2, CAPD2, CNAP1, KIAA0159
Domain Architecture
Description	Condensin complex subunit 1 (Non-SMC condensin I complex subunit D2) (Chromosome condensation-related SMC-associated protein 1) (Chromosome-associated protein D2) (hCAP-D2) (XCAP-D2 homolog).

LBXCO_HUMAN
θ value	3.0926 (rank : 88)	NC score	0.009517 (rank : 103)
Query Neighborhood Hits	138	Target Neighborhood Hits	167	Shared Neighborhood Hits	8
SwissProt Accessions	P84550	Gene names	LBXCOR1
Domain Architecture	No domain graphic available
Description	Ladybird homeobox corepressor 1.

LETM1_MOUSE
θ value	3.0926 (rank : 89)	NC score	0.014122 (rank : 85)
Query Neighborhood Hits	138	Target Neighborhood Hits	240	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Z2I0, Q5PQC5, Q7TMK8, Q80ZX6, Q8CGJ3, Q8K5E5	Gene names	Letm1
Domain Architecture	No domain graphic available
Description	Leucine zipper-EF-hand-containing transmembrane protein 1, mitochondrial precursor.

MCM5_MOUSE
θ value	3.0926 (rank : 90)	NC score	0.011812 (rank : 91)
Query Neighborhood Hits	138	Target Neighborhood Hits	36	Shared Neighborhood Hits	6
SwissProt Accessions	P49718	Gene names	Mcm5, Cdc46, Mcmd5
Domain Architecture
Description	DNA replication licensing factor MCM5 (CDC46 homolog) (P1-CDC46).

OLIG1_HUMAN
θ value	3.0926 (rank : 91)	NC score	0.007924 (rank : 108)
Query Neighborhood Hits	138	Target Neighborhood Hits	85	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TAK6, Q7RTS0	Gene names	OLIG1
Domain Architecture
Description	Oligodendrocyte transcription factor 1 (Oligo1).

RAD52_MOUSE
θ value	3.0926 (rank : 92)	NC score	0.024463 (rank : 75)
Query Neighborhood Hits	138	Target Neighborhood Hits	17	Shared Neighborhood Hits	4
SwissProt Accessions	P43352	Gene names	Rad52
Domain Architecture
Description	DNA repair protein RAD52 homolog.

RD23B_MOUSE
θ value	3.0926 (rank : 93)	NC score	0.011705 (rank : 93)
Query Neighborhood Hits	138	Target Neighborhood Hits	189	Shared Neighborhood Hits	10
SwissProt Accessions	P54728	Gene names	Rad23b, Mhr23b
Domain Architecture
Description	UV excision repair protein RAD23 homolog B (mHR23B) (XP-C repair- complementing complex 58 kDa protein) (p58).

RFC1_HUMAN
θ value	3.0926 (rank : 94)	NC score	0.111310 (rank : 63)
Query Neighborhood Hits	138	Target Neighborhood Hits	352	Shared Neighborhood Hits	44
SwissProt Accessions	P35251, Q5XKF5, Q6PKU0, Q86V41, Q86V46	Gene names	RFC1, RFC140
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (DNA-binding protein PO-GA).

RFC1_MOUSE
θ value	3.0926 (rank : 95)	NC score	0.121034 (rank : 62)
Query Neighborhood Hits	138	Target Neighborhood Hits	290	Shared Neighborhood Hits	49
SwissProt Accessions	P35601	Gene names	Rfc1, Ibf-1, Recc1
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (A1-P145) (Differentiation- specific element-binding protein) (ISRE-binding protein).

RUVB2_HUMAN
θ value	3.0926 (rank : 96)	NC score	0.131961 (rank : 60)
Query Neighborhood Hits	138	Target Neighborhood Hits	43	Shared Neighborhood Hits	38
SwissProt Accessions	Q9Y230, Q6PK27, Q9Y361	Gene names	RUVBL2, TIP48, TIP49B
Domain Architecture
Description	RuvB-like 2 (EC 3.6.1.-) (48 kDa TATA box-binding protein-interacting protein) (48 kDa TBP-interacting protein) (TIP49b) (Repressing pontin 52) (Reptin 52) (51 kDa erythrocyte cytosolic protein) (ECP-51) (TIP60-associated protein 54-beta) (TAP54-beta).

SRRM2_HUMAN
θ value	3.0926 (rank : 97)	NC score	0.020865 (rank : 77)
Query Neighborhood Hits	138	Target Neighborhood Hits	1296	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

SUHW3_MOUSE
θ value	3.0926 (rank : 98)	NC score	-0.000601 (rank : 135)
Query Neighborhood Hits	138	Target Neighborhood Hits	697	Shared Neighborhood Hits	4
SwissProt Accessions	Q6P3Y5, Q6ZPM2, Q8K145	Gene names	Suhw3, Kiaa1584
Domain Architecture	No domain graphic available
Description	Suppressor of hairy wing homolog 3.

TACC3_HUMAN
θ value	3.0926 (rank : 99)	NC score	0.005093 (rank : 120)
Query Neighborhood Hits	138	Target Neighborhood Hits	779	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

AFF4_MOUSE
θ value	4.03905 (rank : 100)	NC score	0.009055 (rank : 104)
Query Neighborhood Hits	138	Target Neighborhood Hits	581	Shared Neighborhood Hits	16
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

BPA1_MOUSE
θ value	4.03905 (rank : 101)	NC score	0.002947 (rank : 124)
Query Neighborhood Hits	138	Target Neighborhood Hits	1477	Shared Neighborhood Hits	21
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

BPAEA_MOUSE
θ value	4.03905 (rank : 102)	NC score	0.006163 (rank : 117)
Query Neighborhood Hits	138	Target Neighborhood Hits	1480	Shared Neighborhood Hits	29
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

HMMR_HUMAN
θ value	4.03905 (rank : 103)	NC score	0.001848 (rank : 130)
Query Neighborhood Hits	138	Target Neighborhood Hits	1082	Shared Neighborhood Hits	18
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

MCM5_HUMAN
θ value	4.03905 (rank : 104)	NC score	0.011051 (rank : 95)
Query Neighborhood Hits	138	Target Neighborhood Hits	37	Shared Neighborhood Hits	6
SwissProt Accessions	P33992, O60785, Q14578, Q9BTJ4, Q9BWL8	Gene names	MCM5, CDC46
Domain Architecture
Description	DNA replication licensing factor MCM5 (CDC46 homolog) (P1-CDC46).

RGS3_HUMAN
θ value	4.03905 (rank : 105)	NC score	0.001209 (rank : 133)
Query Neighborhood Hits	138	Target Neighborhood Hits	1375	Shared Neighborhood Hits	25
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

SRRM1_HUMAN
θ value	4.03905 (rank : 106)	NC score	0.018906 (rank : 79)
Query Neighborhood Hits	138	Target Neighborhood Hits	690	Shared Neighborhood Hits	19
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

BPAEA_HUMAN
θ value	5.27518 (rank : 107)	NC score	0.007566 (rank : 111)
Query Neighborhood Hits	138	Target Neighborhood Hits	1369	Shared Neighborhood Hits	27
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CO6A2_HUMAN
θ value	5.27518 (rank : 108)	NC score	0.002078 (rank : 129)
Query Neighborhood Hits	138	Target Neighborhood Hits	249	Shared Neighborhood Hits	7
SwissProt Accessions	P12110, Q13909, Q13910, Q13911, Q14049, Q16259, Q16597, Q9UML3	Gene names	COL6A2
Domain Architecture
Description	Collagen alpha-2(VI) chain precursor.

DIAP1_MOUSE
θ value	5.27518 (rank : 109)	NC score	0.002696 (rank : 126)
Query Neighborhood Hits	138	Target Neighborhood Hits	839	Shared Neighborhood Hits	19
SwissProt Accessions	O08808	Gene names	Diaph1, Diap1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) (mDIA1) (p140mDIA).

KAD6_HUMAN
θ value	5.27518 (rank : 110)	NC score	0.109915 (rank : 64)
Query Neighborhood Hits	138	Target Neighborhood Hits	46	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Y3D8	Gene names	AK6
Domain Architecture
Description	Adenylate kinase isoenzyme 6 (EC 2.7.4.3) (ATP-AMP transphosphorylase 6).

KLF12_MOUSE
θ value	5.27518 (rank : 111)	NC score	-0.005302 (rank : 144)
Query Neighborhood Hits	138	Target Neighborhood Hits	721	Shared Neighborhood Hits	6
SwissProt Accessions	O35738	Gene names	Klf12, Ap2rep
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 12 (Transcriptional repressor AP-2rep).

RECQ5_HUMAN
θ value	5.27518 (rank : 112)	NC score	0.005566 (rank : 119)
Query Neighborhood Hits	138	Target Neighborhood Hits	390	Shared Neighborhood Hits	16
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

TTK_MOUSE
θ value	5.27518 (rank : 113)	NC score	-0.001729 (rank : 137)
Query Neighborhood Hits	138	Target Neighborhood Hits	803	Shared Neighborhood Hits	9
SwissProt Accessions	P35761	Gene names	Ttk, Esk
Domain Architecture
Description	Dual specificity protein kinase TTK (EC 2.7.12.1) (ESK) (PYT).

ABCF1_MOUSE
θ value	6.88961 (rank : 114)	NC score	0.011737 (rank : 92)
Query Neighborhood Hits	138	Target Neighborhood Hits	321	Shared Neighborhood Hits	10
SwissProt Accessions	Q6P542, Q6NV71	Gene names	Abcf1
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 1.

BRE1B_HUMAN
θ value	6.88961 (rank : 115)	NC score	0.002835 (rank : 125)
Query Neighborhood Hits	138	Target Neighborhood Hits	1040	Shared Neighborhood Hits	21
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

DYHC_HUMAN
θ value	6.88961 (rank : 116)	NC score	0.008982 (rank : 106)
Query Neighborhood Hits	138	Target Neighborhood Hits	733	Shared Neighborhood Hits	23
SwissProt Accessions	Q14204, Q6DKQ7, Q8WU28, Q92814, Q9Y4G5	Gene names	DYNC1H1, DNCH1, DNECL, KIAA0325
Domain Architecture	No domain graphic available
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

DYHC_MOUSE
θ value	6.88961 (rank : 117)	NC score	0.009036 (rank : 105)
Query Neighborhood Hits	138	Target Neighborhood Hits	729	Shared Neighborhood Hits	23
SwissProt Accessions	Q9JHU4	Gene names	Dync1h1, Dnch1, Dnchc1
Domain Architecture
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

EHMT2_HUMAN
θ value	6.88961 (rank : 118)	NC score	-0.001446 (rank : 136)
Query Neighborhood Hits	138	Target Neighborhood Hits	498	Shared Neighborhood Hits	7
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

GSHB_MOUSE
θ value	6.88961 (rank : 119)	NC score	0.007646 (rank : 110)
Query Neighborhood Hits	138	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	P51855	Gene names	Gss
Domain Architecture
Description	Glutathione synthetase (EC 6.3.2.3) (Glutathione synthase) (GSH synthetase) (GSH-S).

LAP4_MOUSE
θ value	6.88961 (rank : 120)	NC score	-0.002074 (rank : 139)
Query Neighborhood Hits	138	Target Neighborhood Hits	590	Shared Neighborhood Hits	7
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

MACF1_HUMAN
θ value	6.88961 (rank : 121)	NC score	0.001209 (rank : 134)
Query Neighborhood Hits	138	Target Neighborhood Hits	1341	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

PDE9A_HUMAN
θ value	6.88961 (rank : 122)	NC score	0.001796 (rank : 131)
Query Neighborhood Hits	138	Target Neighborhood Hits	93	Shared Neighborhood Hits	4
SwissProt Accessions	O76083, O75490, O75491, O95225, Q86SF7, Q86SI6, Q86SJ3, Q86WN3, Q86WN4, Q86WN5, Q86WN6, Q86WN7, Q86WN8, Q86WN9, Q86WP0	Gene names	PDE9A
Domain Architecture
Description	High-affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A (EC 3.1.4.35).

PFD3_HUMAN
θ value	6.88961 (rank : 123)	NC score	0.017768 (rank : 82)
Query Neighborhood Hits	138	Target Neighborhood Hits	24	Shared Neighborhood Hits	4
SwissProt Accessions	P61758, O55228, Q15765, Q5JT81, Q86X96	Gene names	VBP1, PFDN3
Domain Architecture
Description	Prefoldin subunit 3 (Von Hippel-Lindau-binding protein 1) (VHL-binding protein 1) (VBP-1) (HIBBJ46).

PFD3_MOUSE
θ value	6.88961 (rank : 124)	NC score	0.017777 (rank : 81)
Query Neighborhood Hits	138	Target Neighborhood Hits	24	Shared Neighborhood Hits	4
SwissProt Accessions	P61759, O55228, Q15765, Q3U6M9, Q9CPZ0	Gene names	Vbp1, Pfdn3
Domain Architecture
Description	Prefoldin subunit 3 (Von Hippel-Lindau-binding protein 1) (VHL-binding protein 1) (VBP-1).

YBOX2_MOUSE
θ value	6.88961 (rank : 125)	NC score	0.010455 (rank : 99)
Query Neighborhood Hits	138	Target Neighborhood Hits	46	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z2C8, Q5NCW8, Q5NCW9, Q9Z2C7	Gene names	Ybx2, Msy2
Domain Architecture	No domain graphic available
Description	Y-box-binding protein 2 (Germ cell-specific Y-box-binding protein) (FRGY2 homolog).

CJ108_HUMAN
θ value	8.99809 (rank : 126)	NC score	0.007093 (rank : 112)
Query Neighborhood Hits	138	Target Neighborhood Hits	165	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N8Z3	Gene names	C10orf108
Domain Architecture	No domain graphic available
Description	Putative uncharacterized protein C10orf108.

CX039_HUMAN
θ value	8.99809 (rank : 127)	NC score	0.006249 (rank : 115)
Query Neighborhood Hits	138	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	Q6PEV8, Q8WVP6, Q96AV3	Gene names	CXorf39
Domain Architecture	No domain graphic available
Description	Uncharacterized protein CXorf39.

EAN57_HUMAN
θ value	8.99809 (rank : 128)	NC score	0.007762 (rank : 109)
Query Neighborhood Hits	138	Target Neighborhood Hits	62	Shared Neighborhood Hits	8
SwissProt Accessions	O43247, Q6ICF2, Q9Y4V8	Gene names	EAN57
Domain Architecture	No domain graphic available
Description	Protein EAN57.

IMMT_HUMAN
θ value	8.99809 (rank : 129)	NC score	0.004203 (rank : 122)
Query Neighborhood Hits	138	Target Neighborhood Hits	494	Shared Neighborhood Hits	13
SwissProt Accessions	Q16891, Q14539, Q15092, Q68D41, Q69HW5, Q6IBL0, Q7Z3X1, Q8TAJ5, Q9P0V2	Gene names	IMMT, HMP, PIG4
Domain Architecture	No domain graphic available
Description	Mitochondrial inner membrane protein (Mitofilin) (p87/89) (Proliferation-inducing gene 4 protein).

KAD6_MOUSE
θ value	8.99809 (rank : 130)	NC score	0.087678 (rank : 68)
Query Neighborhood Hits	138	Target Neighborhood Hits	34	Shared Neighborhood Hits	20
SwissProt Accessions	Q8VCP8	Gene names	Ak6
Domain Architecture	No domain graphic available
Description	Adenylate kinase isoenzyme 6 (EC 2.7.4.3) (ATP-AMP transphosphorylase 6).

KS6C1_HUMAN
θ value	8.99809 (rank : 131)	NC score	0.006224 (rank : 116)
Query Neighborhood Hits	138	Target Neighborhood Hits	682	Shared Neighborhood Hits	12
SwissProt Accessions	Q96S38, Q8TDD3, Q9NSF4, Q9UL66	Gene names	RPS6KC1, RPK118
Domain Architecture	No domain graphic available
Description	Ribosomal protein S6 kinase delta-1 (EC 2.7.11.1) (52 kDa ribosomal protein S6 kinase) (Ribosomal S6 kinase-like protein with two PSK domains 118 kDa protein) (SPHK1-binding protein).

LSD1_MOUSE
θ value	8.99809 (rank : 132)	NC score	0.011007 (rank : 96)
Query Neighborhood Hits	138	Target Neighborhood Hits	224	Shared Neighborhood Hits	11
SwissProt Accessions	Q6ZQ88, Q6PB53, Q8VEA1	Gene names	Aof2, Kiaa0601, Lsd1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

MAP4_HUMAN
θ value	8.99809 (rank : 133)	NC score	0.010878 (rank : 97)
Query Neighborhood Hits	138	Target Neighborhood Hits	428	Shared Neighborhood Hits	16
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

RAVR2_HUMAN
θ value	8.99809 (rank : 134)	NC score	0.002500 (rank : 127)
Query Neighborhood Hits	138	Target Neighborhood Hits	144	Shared Neighborhood Hits	4
SwissProt Accessions	Q9HCJ3, Q6P141, Q9NPV7	Gene names	RAVER2, KIAA1579
Domain Architecture	No domain graphic available
Description	Ribonucleoprotein PTB-binding 2 (Protein raver-2).

RUVB2_MOUSE
θ value	8.99809 (rank : 135)	NC score	0.125805 (rank : 61)
Query Neighborhood Hits	138	Target Neighborhood Hits	42	Shared Neighborhood Hits	37
SwissProt Accessions	Q9WTM5	Gene names	Ruvbl2
Domain Architecture
Description	RuvB-like 2 (EC 3.6.1.-) (p47 protein).

TF3C2_HUMAN
θ value	8.99809 (rank : 136)	NC score	0.005793 (rank : 118)
Query Neighborhood Hits	138	Target Neighborhood Hits	168	Shared Neighborhood Hits	5
SwissProt Accessions	Q8WUA4, Q16632, Q9BWI7	Gene names	GTF3C2, KIAA0011
Domain Architecture
Description	General transcription factor 3C polypeptide 2 (Transcription factor IIIC-subunit beta) (TF3C-beta) (TFIIIC 110 kDa subunit) (TFIIIC110).

THAP4_HUMAN
θ value	8.99809 (rank : 137)	NC score	0.004643 (rank : 121)
Query Neighborhood Hits	138	Target Neighborhood Hits	92	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WY91, Q53NU7, Q6GRN0, Q6IPJ3, Q9NW26, Q9Y325	Gene names	THAP4
Domain Architecture
Description	THAP domain-containing protein 4.

TTK_HUMAN
θ value	8.99809 (rank : 138)	NC score	-0.002525 (rank : 143)
Query Neighborhood Hits	138	Target Neighborhood Hits	816	Shared Neighborhood Hits	9
SwissProt Accessions	P33981	Gene names	TTK, MPS1L1
Domain Architecture
Description	Dual specificity protein kinase TTK (EC 2.7.12.1) (Phosphotyrosine picked threonine-protein kinase) (PYT).

RFC4_HUMAN
θ value	θ > 10 (rank : 139)	NC score	0.092456 (rank : 67)
Query Neighborhood Hits	138	Target Neighborhood Hits	64	Shared Neighborhood Hits	36
SwissProt Accessions	P35249, Q6FHX7	Gene names	RFC4
Domain Architecture
Description	Replication factor C subunit 4 (Replication factor C 37 kDa subunit) (RF-C 37 kDa subunit) (RFC37) (Activator 1 37 kDa subunit) (A1 37 kDa subunit).

RFC4_MOUSE
θ value	θ > 10 (rank : 140)	NC score	0.082292 (rank : 69)
Query Neighborhood Hits	138	Target Neighborhood Hits	65	Shared Neighborhood Hits	36
SwissProt Accessions	Q99J62	Gene names	Rfc4
Domain Architecture	No domain graphic available
Description	Replication factor C subunit 4.

RFC5_HUMAN
θ value	θ > 10 (rank : 141)	NC score	0.054754 (rank : 70)
Query Neighborhood Hits	138	Target Neighborhood Hits	60	Shared Neighborhood Hits	28
SwissProt Accessions	P40937	Gene names	RFC5
Domain Architecture
Description	Replication factor C subunit 5 (Replication factor C 36 kDa subunit) (RF-C 36 kDa subunit) (RFC36) (Activator 1 36 kDa subunit) (A1 36 kDa subunit).

RFC5_MOUSE
θ value	θ > 10 (rank : 142)	NC score	0.054032 (rank : 71)
Query Neighborhood Hits	138	Target Neighborhood Hits	58	Shared Neighborhood Hits	32
SwissProt Accessions	Q9D0F6	Gene names	Rfc5
Domain Architecture
Description	Replication factor C subunit 5 (Replication factor C 36 kDa subunit) (RF-C 36 kDa subunit) (RFC36) (Activator 1 36 kDa subunit) (A1 36 kDa subunit).

THNSL_HUMAN
θ value	θ > 10 (rank : 143)	NC score	0.097123 (rank : 66)
Query Neighborhood Hits	138	Target Neighborhood Hits	47	Shared Neighborhood Hits	35
SwissProt Accessions	Q8IYQ7, Q5VV21	Gene names	THNSL1
Domain Architecture	No domain graphic available
Description	Threonine synthase-like 1.

THNSL_MOUSE
θ value	θ > 10 (rank : 144)	NC score	0.104160 (rank : 65)
Query Neighborhood Hits	138	Target Neighborhood Hits	47	Shared Neighborhood Hits	32
SwissProt Accessions	Q8BH55	Gene names	Thnsl1
Domain Architecture	No domain graphic available
Description	Threonine synthase-like 1.

Hits sorted by NC score

SPAST_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	138	Target Neighborhood Hits	138	Shared Neighborhood Hits	138
SwissProt Accessions	Q9QYY8, Q6ZPY6, Q80VE0, Q9CVK0	Gene names	Spast, Kiaa1083, Spg4
Domain Architecture	No domain graphic available
Description	Spastin.

SPAST_HUMAN
NC score	0.997290 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	138	Target Neighborhood Hits	100	Shared Neighborhood Hits	89
SwissProt Accessions	Q9UBP0, Q9UPR9	Gene names	SPAST, KIAA1083, SPG4
Domain Architecture
Description	Spastin.

KATL1_MOUSE
NC score	0.963025 (rank : 3)	θ value	5.7252e-63 (rank : 6)
Query Neighborhood Hits	138	Target Neighborhood Hits	77	Shared Neighborhood Hits	63
SwissProt Accessions	Q8K0T4	Gene names	Katnal1
Domain Architecture	No domain graphic available
Description	Katanin p60 ATPase-containing subunit A-like 1 (EC 3.6.4.3) (Katanin p60 subunit A-like 1) (p60 katanin-like 1).

KATL1_HUMAN
NC score	0.962697 (rank : 4)	θ value	1.50663e-63 (rank : 4)
Query Neighborhood Hits	138	Target Neighborhood Hits	80	Shared Neighborhood Hits	63
SwissProt Accessions	Q9BW62	Gene names	KATNAL1
Domain Architecture	No domain graphic available
Description	Katanin p60 ATPase-containing subunit A-like 1 (EC 3.6.4.3) (Katanin p60 subunit A-like 1) (p60 katanin-like 1).

KTNA1_HUMAN
NC score	0.961469 (rank : 5)	θ value	7.47731e-63 (rank : 7)
Query Neighborhood Hits	138	Target Neighborhood Hits	117	Shared Neighborhood Hits	65
SwissProt Accessions	O75449, Q5TFA8, Q5TFA9, Q86VN2, Q9NU52	Gene names	KATNA1
Domain Architecture	No domain graphic available
Description	Katanin p60 ATPase-containing subunit A1 (EC 3.6.4.3) (Katanin p60 subunit A1) (p60 katanin).

KTNA1_MOUSE
NC score	0.959766 (rank : 6)	θ value	6.32992e-62 (rank : 8)
Query Neighborhood Hits	138	Target Neighborhood Hits	123	Shared Neighborhood Hits	67
SwissProt Accessions	Q9WV86	Gene names	Katna1
Domain Architecture	No domain graphic available
Description	Katanin p60 ATPase-containing subunit A1 (EC 3.6.4.3) (Katanin p60 subunit A1) (p60 katanin) (Lipotransin).

ATAD1_HUMAN
NC score	0.958906 (rank : 7)	θ value	2.3352e-48 (rank : 13)
Query Neighborhood Hits	138	Target Neighborhood Hits	75	Shared Neighborhood Hits	61
SwissProt Accessions	Q8NBU5, Q6P4B9, Q8N3G1, Q8WYR9, Q969Y3	Gene names	ATAD1
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 1.

ATAD1_MOUSE
NC score	0.958906 (rank : 8)	θ value	2.3352e-48 (rank : 14)
Query Neighborhood Hits	138	Target Neighborhood Hits	75	Shared Neighborhood Hits	61
SwissProt Accessions	Q9D5T0, Q3U8V2, Q9D7A4	Gene names	Atad1
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 1.

VPS4B_HUMAN
NC score	0.957480 (rank : 9)	θ value	8.26713e-62 (rank : 9)
Query Neighborhood Hits	138	Target Neighborhood Hits	87	Shared Neighborhood Hits	62
SwissProt Accessions	O75351, Q9GZS7	Gene names	VPS4B, SKD1, VPS42
Domain Architecture
Description	Vacuolar protein sorting-associating protein 4B (Protein SKD1).

VPS4B_MOUSE
NC score	0.956956 (rank : 10)	θ value	1.41016e-61 (rank : 10)
Query Neighborhood Hits	138	Target Neighborhood Hits	86	Shared Neighborhood Hits	61
SwissProt Accessions	P46467, Q91W22, Q9R1C9	Gene names	Vps4b, Skd1
Domain Architecture
Description	Vacuolar protein sorting-associating protein 4B (Protein SKD1).

VPS4A_HUMAN
NC score	0.953887 (rank : 11)	θ value	1.31987e-59 (rank : 11)
Query Neighborhood Hits	138	Target Neighborhood Hits	95	Shared Neighborhood Hits	62
SwissProt Accessions	Q9UN37, Q8TF07, Q9UI03, Q9Y582	Gene names	VPS4A, VPS4
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associating protein 4A (SKD2 protein) (hVPS4) (VPS4-1).

VPS4A_MOUSE
NC score	0.953855 (rank : 12)	θ value	1.31987e-59 (rank : 12)
Query Neighborhood Hits	138	Target Neighborhood Hits	94	Shared Neighborhood Hits	62
SwissProt Accessions	Q8VEJ9, Q3TXT2	Gene names	Vps4a
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associating protein 4A.

FIGN_MOUSE
NC score	0.939964 (rank : 13)	θ value	6.76295e-64 (rank : 3)
Query Neighborhood Hits	138	Target Neighborhood Hits	165	Shared Neighborhood Hits	57
SwissProt Accessions	Q9ERZ6, Q3TPB0, Q3UP57, Q6PCM0	Gene names	Fign
Domain Architecture	No domain graphic available
Description	Fidgetin.

FIGN_HUMAN
NC score	0.935643 (rank : 14)	θ value	2.56992e-63 (rank : 5)
Query Neighborhood Hits	138	Target Neighborhood Hits	176	Shared Neighborhood Hits	57
SwissProt Accessions	Q5HY92, Q9H6M5, Q9NVZ9	Gene names	FIGN
Domain Architecture	No domain graphic available
Description	Fidgetin.

PRS10_HUMAN
NC score	0.921638 (rank : 15)	θ value	2.50655e-34 (rank : 21)
Query Neighborhood Hits	138	Target Neighborhood Hits	95	Shared Neighborhood Hits	61
SwissProt Accessions	P62333, P49719, Q6IBU3, Q92524	Gene names	PSMC6, SUG2
Domain Architecture
Description	26S protease regulatory subunit S10B (Proteasome subunit p42) (Proteasome 26S subunit ATPase 6).

PRS10_MOUSE
NC score	0.921638 (rank : 16)	θ value	2.50655e-34 (rank : 22)
Query Neighborhood Hits	138	Target Neighborhood Hits	95	Shared Neighborhood Hits	61
SwissProt Accessions	P62334, P49719, Q3TKK1, Q810A6, Q92524, Q9CXH9	Gene names	Psmc6, Sug2
Domain Architecture
Description	26S protease regulatory subunit S10B (Proteasome subunit p42) (Proteasome 26S subunit ATPase 6).

TERA_HUMAN
NC score	0.920724 (rank : 17)	θ value	3.16345e-37 (rank : 15)
Query Neighborhood Hits	138	Target Neighborhood Hits	76	Shared Neighborhood Hits	62
SwissProt Accessions	P55072, Q969G7	Gene names	VCP
Domain Architecture
Description	Transitional endoplasmic reticulum ATPase (TER ATPase) (15S Mg(2+)- ATPase p97 subunit) (Valosin-containing protein) (VCP).

TERA_MOUSE
NC score	0.920685 (rank : 18)	θ value	3.16345e-37 (rank : 16)
Query Neighborhood Hits	138	Target Neighborhood Hits	76	Shared Neighborhood Hits	62
SwissProt Accessions	Q01853	Gene names	Vcp
Domain Architecture
Description	Transitional endoplasmic reticulum ATPase (TER ATPase) (15S Mg(2+)- ATPase p97 subunit) (Valosin-containing protein) (VCP).

PRS8_HUMAN
NC score	0.919217 (rank : 19)	θ value	1.12514e-34 (rank : 19)
Query Neighborhood Hits	138	Target Neighborhood Hits	117	Shared Neighborhood Hits	61
SwissProt Accessions	P62195, O35051, O43208, P47210, P52915, P52916	Gene names	PSMC5, SUG1
Domain Architecture
Description	26S protease regulatory subunit 8 (Proteasome 26S subunit ATPase 5) (Proteasome subunit p45) (p45/SUG) (Thyroid hormone receptor- interacting protein 1) (TRIP1).

PRS8_MOUSE
NC score	0.919217 (rank : 20)	θ value	1.12514e-34 (rank : 20)
Query Neighborhood Hits	138	Target Neighborhood Hits	117	Shared Neighborhood Hits	61
SwissProt Accessions	P62196, O35051, P47210, P52915, P52916, Q3UL51, Q9CWN5	Gene names	Psmc5, Sug1
Domain Architecture
Description	26S protease regulatory subunit 8 (Proteasome 26S subunit ATPase 5) (Proteasome subunit p45) (p45/SUG) (mSUG1).

PRS6A_MOUSE
NC score	0.917412 (rank : 21)	θ value	4.72714e-33 (rank : 26)
Query Neighborhood Hits	138	Target Neighborhood Hits	85	Shared Neighborhood Hits	57
SwissProt Accessions	O88685	Gene names	Psmc3, Tbp1
Domain Architecture
Description	26S protease regulatory subunit 6A (Proteasome 26S subunit ATPase 3) (TAT-binding protein 1) (TBP-1).

PRS6A_HUMAN
NC score	0.917300 (rank : 22)	θ value	3.61944e-33 (rank : 25)
Query Neighborhood Hits	138	Target Neighborhood Hits	87	Shared Neighborhood Hits	57
SwissProt Accessions	P17980, Q96HD3	Gene names	PSMC3, TBP1
Domain Architecture
Description	26S protease regulatory subunit 6A (Proteasome 26S subunit ATPase 3) (TAT-binding protein 1) (TBP-1) (Proteasome subunit P50).

PRS4_HUMAN
NC score	0.916139 (rank : 23)	θ value	2.12192e-33 (rank : 23)
Query Neighborhood Hits	138	Target Neighborhood Hits	84	Shared Neighborhood Hits	62
SwissProt Accessions	P62191, P49014, Q03527, Q6IAW0, Q96AZ3	Gene names	PSMC1
Domain Architecture
Description	26S protease regulatory subunit 4 (P26s4) (Proteasome 26S subunit ATPase 1).

PRS4_MOUSE
NC score	0.916139 (rank : 24)	θ value	2.12192e-33 (rank : 24)
Query Neighborhood Hits	138	Target Neighborhood Hits	84	Shared Neighborhood Hits	62
SwissProt Accessions	P62192, P49014, Q03527, Q96AZ3	Gene names	Psmc1
Domain Architecture
Description	26S protease regulatory subunit 4 (P26s4) (Proteasome 26S subunit ATPase 1).

PEX1_HUMAN
NC score	0.914109 (rank : 25)	θ value	4.42448e-31 (rank : 30)
Query Neighborhood Hits	138	Target Neighborhood Hits	98	Shared Neighborhood Hits	60
SwissProt Accessions	O43933, Q96S71, Q96S72, Q96S73, Q99994	Gene names	PEX1
Domain Architecture
Description	Peroxisome biogenesis factor 1 (Peroxin-1) (Peroxisome biogenesis disorder protein 1).

NVL_MOUSE
NC score	0.913965 (rank : 26)	θ value	5.96599e-36 (rank : 18)
Query Neighborhood Hits	138	Target Neighborhood Hits	110	Shared Neighborhood Hits	65
SwissProt Accessions	Q9DBY8, Q3USC4, Q8BW27, Q8K2B5	Gene names	Nvl
Domain Architecture
Description	Nuclear valosin-containing protein-like (Nuclear VCP-like protein) (NVLp).

NVL_HUMAN
NC score	0.913628 (rank : 27)	θ value	2.67802e-36 (rank : 17)
Query Neighborhood Hits	138	Target Neighborhood Hits	112	Shared Neighborhood Hits	65
SwissProt Accessions	O15381, Q96EM7	Gene names	NVL
Domain Architecture
Description	Nuclear valosin-containing protein-like (Nuclear VCP-like protein) (NVLp).

PRS6B_HUMAN
NC score	0.912149 (rank : 28)	θ value	4.89182e-30 (rank : 35)
Query Neighborhood Hits	138	Target Neighborhood Hits	85	Shared Neighborhood Hits	58
SwissProt Accessions	P43686, Q96FV5, Q9UBM3, Q9UEX3	Gene names	PSMC4, TBP7
Domain Architecture
Description	26S protease regulatory subunit 6B (Proteasome 26S subunit ATPase 4) (MIP224) (MB67-interacting protein) (TAT-binding protein 7) (TBP-7).

PRS6B_MOUSE
NC score	0.910988 (rank : 29)	θ value	2.42779e-29 (rank : 36)
Query Neighborhood Hits	138	Target Neighborhood Hits	89	Shared Neighborhood Hits	59
SwissProt Accessions	P54775	Gene names	Psmc4, Tbp7
Domain Architecture
Description	26S protease regulatory subunit 6B (Proteasome 26S subunit ATPase 4) (MIP224) (MB67-interacting protein) (TAT-binding protein 7) (TBP-7) (CIP21).

PRS7_HUMAN
NC score	0.910334 (rank : 30)	θ value	7.06379e-29 (rank : 38)
Query Neighborhood Hits	138	Target Neighborhood Hits	66	Shared Neighborhood Hits	59
SwissProt Accessions	P35998	Gene names	PSMC2, MSS1
Domain Architecture
Description	26S protease regulatory subunit 7 (Proteasome 26S subunit ATPase 2) (Protein MSS1).

PRS7_MOUSE
NC score	0.910326 (rank : 31)	θ value	7.06379e-29 (rank : 39)
Query Neighborhood Hits	138	Target Neighborhood Hits	67	Shared Neighborhood Hits	59
SwissProt Accessions	P46471, O08531, Q3TGX5, Q9DBA1	Gene names	Psmc2, Mss1
Domain Architecture
Description	26S protease regulatory subunit 7 (Proteasome 26S subunit ATPase 2) (Protein MSS1).

PEX6_HUMAN
NC score	0.904410 (rank : 32)	θ value	9.8567e-31 (rank : 31)
Query Neighborhood Hits	138	Target Neighborhood Hits	99	Shared Neighborhood Hits	61
SwissProt Accessions	Q13608, Q8WYQ2, Q99476	Gene names	PEX6, PXAAA1
Domain Architecture
Description	Peroxisome assembly factor 2 (PAF-2) (Peroxisomal-type ATPase 1) (Peroxin-6) (Peroxisomal biogenesis factor 6).

PEX6_MOUSE
NC score	0.904334 (rank : 33)	θ value	3.3877e-31 (rank : 29)
Query Neighborhood Hits	138	Target Neighborhood Hits	94	Shared Neighborhood Hits	60
SwissProt Accessions	Q99LC9, Q6YNQ9	Gene names	Pex6
Domain Architecture	No domain graphic available
Description	Peroxisome assembly factor 2 (PAF-2) (Peroxisomal-type ATPase 1) (Peroxin-6) (Peroxisomal biogenesis factor 6).

YMEL1_MOUSE
NC score	0.897238 (rank : 34)	θ value	3.17079e-29 (rank : 37)
Query Neighborhood Hits	138	Target Neighborhood Hits	76	Shared Neighborhood Hits	57
SwissProt Accessions	O88967, Q7TNN5	Gene names	Yme1l1
Domain Architecture
Description	ATP-dependent metalloprotease YME1L1 (EC 3.4.24.-) (YME1-like protein 1) (ATP-dependent metalloprotease FtsH1).

SPG7_HUMAN
NC score	0.894784 (rank : 35)	θ value	1.12775e-26 (rank : 41)
Query Neighborhood Hits	138	Target Neighborhood Hits	71	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UQ90, O75756, Q96IB0	Gene names	SPG7, CAR, CMAR, PGN
Domain Architecture
Description	Paraplegin (EC 3.4.24.-) (Spastic paraplegia protein 7).

YMEL1_HUMAN
NC score	0.894178 (rank : 36)	θ value	1.33217e-27 (rank : 40)
Query Neighborhood Hits	138	Target Neighborhood Hits	73	Shared Neighborhood Hits	57
SwissProt Accessions	Q96TA2, Q9H1Q0, Q9UMR9	Gene names	YME1L1, FTSH1, YME1L
Domain Architecture
Description	ATP-dependent metalloprotease YME1L1 (EC 3.4.24.-) (YME1-like protein 1) (ATP-dependent metalloprotease FtsH1) (Meg-4) (Presenilin- associated metalloprotease) (PAMP).

AFG31_MOUSE
NC score	0.893989 (rank : 37)	θ value	1.28732e-30 (rank : 32)
Query Neighborhood Hits	138	Target Neighborhood Hits	74	Shared Neighborhood Hits	63
SwissProt Accessions	Q920A7	Gene names	Afg3l1
Domain Architecture
Description	AFG3-like protein 1 (EC 3.4.24.-).

AFG32_MOUSE
NC score	0.889543 (rank : 38)	θ value	1.6813e-30 (rank : 34)
Query Neighborhood Hits	138	Target Neighborhood Hits	73	Shared Neighborhood Hits	63
SwissProt Accessions	Q8JZQ2	Gene names	Afg3l2
Domain Architecture	No domain graphic available
Description	AFG3-like protein 2 (EC 3.4.24.-).

AFG32_HUMAN
NC score	0.889516 (rank : 39)	θ value	1.6813e-30 (rank : 33)
Query Neighborhood Hits	138	Target Neighborhood Hits	72	Shared Neighborhood Hits	63
SwissProt Accessions	Q9Y4W6	Gene names	AFG3L2
Domain Architecture
Description	AFG3-like protein 2 (EC 3.4.24.-) (Paraplegin-like protein).

NSF_HUMAN
NC score	0.866928 (rank : 40)	θ value	2.27762e-19 (rank : 42)
Query Neighborhood Hits	138	Target Neighborhood Hits	74	Shared Neighborhood Hits	63
SwissProt Accessions	P46459, Q9UKZ2	Gene names	NSF
Domain Architecture
Description	Vesicle-fusing ATPase (EC 3.6.4.6) (Vesicular-fusion protein NSF) (N- ethylmaleimide sensitive fusion protein) (NEM-sensitive fusion protein).

ATAD2_MOUSE
NC score	0.866736 (rank : 41)	θ value	1.16434e-31 (rank : 27)
Query Neighborhood Hits	138	Target Neighborhood Hits	167	Shared Neighborhood Hits	60
SwissProt Accessions	Q8CDM1	Gene names	Atad2
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 2.

NSF_MOUSE
NC score	0.866570 (rank : 42)	θ value	2.27762e-19 (rank : 43)
Query Neighborhood Hits	138	Target Neighborhood Hits	73	Shared Neighborhood Hits	60
SwissProt Accessions	P46460	Gene names	Nsf, Skd2
Domain Architecture
Description	Vesicle-fusing ATPase (EC 3.6.4.6) (Vesicular-fusion protein NSF) (N- ethylmaleimide sensitive fusion protein) (NEM-sensitive fusion protein) (SKD2 protein).

ATAD2_HUMAN
NC score	0.849238 (rank : 43)	θ value	1.52067e-31 (rank : 28)
Query Neighborhood Hits	138	Target Neighborhood Hits	322	Shared Neighborhood Hits	61
SwissProt Accessions	Q6PL18, Q658P2, Q68CQ0, Q6PJV6, Q8N890, Q9UHS5	Gene names	ATAD2
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 2.

TRP13_MOUSE
NC score	0.705035 (rank : 44)	θ value	9.92553e-07 (rank : 50)
Query Neighborhood Hits	138	Target Neighborhood Hits	81	Shared Neighborhood Hits	56
SwissProt Accessions	Q3UA06, Q3UQG6, Q9CWW8	Gene names	Trip13
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 13 (Thyroid hormone receptor interactor 13) (Trip-13).

TRP13_HUMAN
NC score	0.701789 (rank : 45)	θ value	9.92553e-07 (rank : 49)
Query Neighborhood Hits	138	Target Neighborhood Hits	81	Shared Neighborhood Hits	56
SwissProt Accessions	Q15645, O15324	Gene names	TRIP13
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 13 (Thyroid hormone receptor interactor 13) (Trip-13) (Human papillomavirus type 16 E1 protein- binding protein) (HPV16 E1 protein-binding protein) (16E1-BP).

ATD3A_HUMAN
NC score	0.650376 (rank : 46)	θ value	5.08577e-11 (rank : 44)
Query Neighborhood Hits	138	Target Neighborhood Hits	248	Shared Neighborhood Hits	64
SwissProt Accessions	Q9NVI7, Q8N275, Q96A50	Gene names	ATAD3A
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 3A.

ATD3B_HUMAN
NC score	0.631425 (rank : 47)	θ value	5.62301e-10 (rank : 45)
Query Neighborhood Hits	138	Target Neighborhood Hits	340	Shared Neighborhood Hits	65
SwissProt Accessions	Q5T9A4, Q6ZRB5, Q9BUK4, Q9ULE7	Gene names	ATAD3B, KIAA1273
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 3B.

ATAD3_MOUSE
NC score	0.623862 (rank : 48)	θ value	1.63604e-09 (rank : 46)
Query Neighborhood Hits	138	Target Neighborhood Hits	326	Shared Neighborhood Hits	67
SwissProt Accessions	Q925I1, Q3UE74, Q69ZM7, Q8C6C6	Gene names	Atad3, Atad3a, Kiaa1273
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 3 (AAA-ATPase TOB3).

BCS1_HUMAN
NC score	0.602644 (rank : 49)	θ value	0.00134147 (rank : 52)
Query Neighborhood Hits	138	Target Neighborhood Hits	61	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Y276, Q7Z2V7	Gene names	BCS1L, BCS1
Domain Architecture
Description	Mitochondrial chaperone BCS1 (BCS1-like protein) (H-BCS1).

BCS1_MOUSE
NC score	0.587966 (rank : 50)	θ value	0.00665767 (rank : 55)
Query Neighborhood Hits	138	Target Neighborhood Hits	64	Shared Neighborhood Hits	50
SwissProt Accessions	Q9CZP5	Gene names	Bcs1l
Domain Architecture
Description	Mitochondrial chaperone BCS1 (BCS1-like protein).

LONM_HUMAN
NC score	0.435653 (rank : 51)	θ value	0.00035302 (rank : 51)
Query Neighborhood Hits	138	Target Neighborhood Hits	130	Shared Neighborhood Hits	57
SwissProt Accessions	P36776, P36777, Q9UQ95	Gene names	PRSS15
Domain Architecture
Description	Lon protease homolog, mitochondrial precursor (EC 3.4.21.-) (Lon protease-like protein) (LONP) (LONHs).

CLPX_HUMAN
NC score	0.429934 (rank : 52)	θ value	0.00134147 (rank : 53)
Query Neighborhood Hits	138	Target Neighborhood Hits	72	Shared Neighborhood Hits	51
SwissProt Accessions	O76031, Q9H4D9	Gene names	CLPX
Domain Architecture
Description	ATP-dependent Clp protease ATP-binding subunit ClpX-like, mitochondrial precursor.

CLPX_MOUSE
NC score	0.426891 (rank : 53)	θ value	0.00134147 (rank : 54)
Query Neighborhood Hits	138	Target Neighborhood Hits	73	Shared Neighborhood Hits	51
SwissProt Accessions	Q9JHS4, Q9WVD1	Gene names	Clpx
Domain Architecture
Description	ATP-dependent Clp protease ATP-binding subunit ClpX-like, mitochondrial precursor.

RUVB1_HUMAN
NC score	0.334037 (rank : 54)	θ value	0.00665767 (rank : 56)
Query Neighborhood Hits	138	Target Neighborhood Hits	78	Shared Neighborhood Hits	57
SwissProt Accessions	Q9Y265, Q9BSX9	Gene names	RUVBL1, NMP238, TIP49, TIP49A
Domain Architecture
Description	RuvB-like 1 (EC 3.6.1.-) (49 kDa TATA box-binding protein-interacting protein) (49 kDa TBP-interacting protein) (TIP49a) (Pontin 52) (Nuclear matrix protein 238) (NMP 238) (54 kDa erythrocyte cytosolic protein) (ECP-54) (TIP60-associated protein 54-alpha) (TAP54-alpha).

RUVB1_MOUSE
NC score	0.333997 (rank : 55)	θ value	0.00665767 (rank : 57)
Query Neighborhood Hits	138	Target Neighborhood Hits	78	Shared Neighborhood Hits	57
SwissProt Accessions	P60122, O35753	Gene names	Ruvbl1, Tip49, Tip49a
Domain Architecture
Description	RuvB-like 1 (EC 3.6.1.-) (49 kDa TATA box-binding protein-interacting protein) (49 kDa TBP-interacting protein) (TIP49a) (Pontin 52) (DNA helicase p50).

WRIP1_HUMAN
NC score	0.231533 (rank : 56)	θ value	0.365318 (rank : 62)
Query Neighborhood Hits	138	Target Neighborhood Hits	100	Shared Neighborhood Hits	52
SwissProt Accessions	Q96S55, Q53EP6, Q59ET8, Q5W0E2, Q5W0E4, Q8WV26, Q9H681, Q9NRJ6	Gene names	WRNIP1, WHIP
Domain Architecture	No domain graphic available
Description	ATPase WRNIP1 (Werner helicase-interacting protein 1).

WRIP1_MOUSE
NC score	0.228754 (rank : 57)	θ value	0.62314 (rank : 65)
Query Neighborhood Hits	138	Target Neighborhood Hits	93	Shared Neighborhood Hits	52
SwissProt Accessions	Q91XU0, Q3TCT7, Q6PDF0, Q8BUW5, Q8BWP6, Q8BY55, Q921W3, Q9EQL3	Gene names	Wrnip1, Whip
Domain Architecture	No domain graphic available
Description	ATPase WRNIP1 (Werner helicase-interacting protein 1).

SPG20_MOUSE
NC score	0.152692 (rank : 58)	θ value	4.0297e-08 (rank : 48)
Query Neighborhood Hits	138	Target Neighborhood Hits	33	Shared Neighborhood Hits	5
SwissProt Accessions	Q8R1X6, Q6ZQ87, Q8BJD3, Q8BM37, Q8BZ63	Gene names	Spg20, Kiaa0610
Domain Architecture	No domain graphic available
Description	Spartin.

SPG20_HUMAN
NC score	0.152360 (rank : 59)	θ value	3.08544e-08 (rank : 47)
Query Neighborhood Hits	138	Target Neighborhood Hits	28	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N0X7, O60349, Q86Y67, Q9H1T2, Q9H1T3	Gene names	SPG20, KIAA0610, TAHCCP1
Domain Architecture	No domain graphic available
Description	Spartin (Trans-activated by hepatitis C virus core protein 1).

RUVB2_HUMAN
NC score	0.131961 (rank : 60)	θ value	3.0926 (rank : 96)
Query Neighborhood Hits	138	Target Neighborhood Hits	43	Shared Neighborhood Hits	38
SwissProt Accessions	Q9Y230, Q6PK27, Q9Y361	Gene names	RUVBL2, TIP48, TIP49B
Domain Architecture
Description	RuvB-like 2 (EC 3.6.1.-) (48 kDa TATA box-binding protein-interacting protein) (48 kDa TBP-interacting protein) (TIP49b) (Repressing pontin 52) (Reptin 52) (51 kDa erythrocyte cytosolic protein) (ECP-51) (TIP60-associated protein 54-beta) (TAP54-beta).

RUVB2_MOUSE
NC score	0.125805 (rank : 61)	θ value	8.99809 (rank : 135)
Query Neighborhood Hits	138	Target Neighborhood Hits	42	Shared Neighborhood Hits	37
SwissProt Accessions	Q9WTM5	Gene names	Ruvbl2
Domain Architecture
Description	RuvB-like 2 (EC 3.6.1.-) (p47 protein).

RFC1_MOUSE
NC score	0.121034 (rank : 62)	θ value	3.0926 (rank : 95)
Query Neighborhood Hits	138	Target Neighborhood Hits	290	Shared Neighborhood Hits	49
SwissProt Accessions	P35601	Gene names	Rfc1, Ibf-1, Recc1
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (A1-P145) (Differentiation- specific element-binding protein) (ISRE-binding protein).

RFC1_HUMAN
NC score	0.111310 (rank : 63)	θ value	3.0926 (rank : 94)
Query Neighborhood Hits	138	Target Neighborhood Hits	352	Shared Neighborhood Hits	44
SwissProt Accessions	P35251, Q5XKF5, Q6PKU0, Q86V41, Q86V46	Gene names	RFC1, RFC140
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (DNA-binding protein PO-GA).

KAD6_HUMAN
NC score	0.109915 (rank : 64)	θ value	5.27518 (rank : 110)
Query Neighborhood Hits	138	Target Neighborhood Hits	46	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Y3D8	Gene names	AK6
Domain Architecture
Description	Adenylate kinase isoenzyme 6 (EC 2.7.4.3) (ATP-AMP transphosphorylase 6).

THNSL_MOUSE
NC score	0.104160 (rank : 65)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	138	Target Neighborhood Hits	47	Shared Neighborhood Hits	32
SwissProt Accessions	Q8BH55	Gene names	Thnsl1
Domain Architecture	No domain graphic available
Description	Threonine synthase-like 1.

THNSL_HUMAN
NC score	0.097123 (rank : 66)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	138	Target Neighborhood Hits	47	Shared Neighborhood Hits	35
SwissProt Accessions	Q8IYQ7, Q5VV21	Gene names	THNSL1
Domain Architecture	No domain graphic available
Description	Threonine synthase-like 1.

RFC4_HUMAN
NC score	0.092456 (rank : 67)	θ value	θ > 10 (rank : 139)
Query Neighborhood Hits	138	Target Neighborhood Hits	64	Shared Neighborhood Hits	36
SwissProt Accessions	P35249, Q6FHX7	Gene names	RFC4
Domain Architecture
Description	Replication factor C subunit 4 (Replication factor C 37 kDa subunit) (RF-C 37 kDa subunit) (RFC37) (Activator 1 37 kDa subunit) (A1 37 kDa subunit).

KAD6_MOUSE
NC score	0.087678 (rank : 68)	θ value	8.99809 (rank : 130)
Query Neighborhood Hits	138	Target Neighborhood Hits	34	Shared Neighborhood Hits	20
SwissProt Accessions	Q8VCP8	Gene names	Ak6
Domain Architecture	No domain graphic available
Description	Adenylate kinase isoenzyme 6 (EC 2.7.4.3) (ATP-AMP transphosphorylase 6).

RFC4_MOUSE
NC score	0.082292 (rank : 69)	θ value	θ > 10 (rank : 140)
Query Neighborhood Hits	138	Target Neighborhood Hits	65	Shared Neighborhood Hits	36
SwissProt Accessions	Q99J62	Gene names	Rfc4
Domain Architecture	No domain graphic available
Description	Replication factor C subunit 4.

RFC5_HUMAN
NC score	0.054754 (rank : 70)	θ value	θ > 10 (rank : 141)
Query Neighborhood Hits	138	Target Neighborhood Hits	60	Shared Neighborhood Hits	28
SwissProt Accessions	P40937	Gene names	RFC5
Domain Architecture
Description	Replication factor C subunit 5 (Replication factor C 36 kDa subunit) (RF-C 36 kDa subunit) (RFC36) (Activator 1 36 kDa subunit) (A1 36 kDa subunit).

RFC5_MOUSE
NC score	0.054032 (rank : 71)	θ value	θ > 10 (rank : 142)
Query Neighborhood Hits	138	Target Neighborhood Hits	58	Shared Neighborhood Hits	32
SwissProt Accessions	Q9D0F6	Gene names	Rfc5
Domain Architecture
Description	Replication factor C subunit 5 (Replication factor C 36 kDa subunit) (RF-C 36 kDa subunit) (RFC36) (Activator 1 36 kDa subunit) (A1 36 kDa subunit).

SPN1_MOUSE
NC score	0.038567 (rank : 72)	θ value	0.21417 (rank : 59)
Query Neighborhood Hits	138	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	Q80W37	Gene names	Snupn, Rnut1
Domain Architecture	No domain graphic available
Description	Snurportin-1 (RNA U transporter 1).

CJ012_HUMAN
NC score	0.034926 (rank : 73)	θ value	0.163984 (rank : 58)
Query Neighborhood Hits	138	Target Neighborhood Hits	467	Shared Neighborhood Hits	18
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

NIP30_MOUSE
NC score	0.026730 (rank : 74)	θ value	2.36792 (rank : 82)
Query Neighborhood Hits	138	Target Neighborhood Hits	76	Shared Neighborhood Hits	3
SwissProt Accessions	Q91WE2, Q8R0C9	Gene names	Nip30
Domain Architecture	No domain graphic available
Description	NEFA-interacting nuclear protein NIP30.

RAD52_MOUSE
NC score	0.024463 (rank : 75)	θ value	3.0926 (rank : 92)
Query Neighborhood Hits	138	Target Neighborhood Hits	17	Shared Neighborhood Hits	4
SwissProt Accessions	P43352	Gene names	Rad52
Domain Architecture
Description	DNA repair protein RAD52 homolog.

SRRM2_MOUSE
NC score	0.021710 (rank : 76)	θ value	1.06291 (rank : 67)
Query Neighborhood Hits	138	Target Neighborhood Hits	1470	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

SRRM2_HUMAN
NC score	0.020865 (rank : 77)	θ value	3.0926 (rank : 97)
Query Neighborhood Hits	138	Target Neighborhood Hits	1296	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

SRRM1_MOUSE
NC score	0.020213 (rank : 78)	θ value	0.365318 (rank : 61)
Query Neighborhood Hits	138	Target Neighborhood Hits	966	Shared Neighborhood Hits	23
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

SRRM1_HUMAN
NC score	0.018906 (rank : 79)	θ value	4.03905 (rank : 106)
Query Neighborhood Hits	138	Target Neighborhood Hits	690	Shared Neighborhood Hits	19
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

BAT3_MOUSE
NC score	0.018302 (rank : 80)	θ value	1.38821 (rank : 69)
Query Neighborhood Hits	138	Target Neighborhood Hits	518	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

PFD3_MOUSE
NC score	0.017777 (rank : 81)	θ value	6.88961 (rank : 124)
Query Neighborhood Hits	138	Target Neighborhood Hits	24	Shared Neighborhood Hits	4
SwissProt Accessions	P61759, O55228, Q15765, Q3U6M9, Q9CPZ0	Gene names	Vbp1, Pfdn3
Domain Architecture
Description	Prefoldin subunit 3 (Von Hippel-Lindau-binding protein 1) (VHL-binding protein 1) (VBP-1).

PFD3_HUMAN
NC score	0.017768 (rank : 82)	θ value	6.88961 (rank : 123)
Query Neighborhood Hits	138	Target Neighborhood Hits	24	Shared Neighborhood Hits	4
SwissProt Accessions	P61758, O55228, Q15765, Q5JT81, Q86X96	Gene names	VBP1, PFDN3
Domain Architecture
Description	Prefoldin subunit 3 (Von Hippel-Lindau-binding protein 1) (VHL-binding protein 1) (VBP-1) (HIBBJ46).

ST5_MOUSE
NC score	0.014855 (rank : 83)	θ value	0.62314 (rank : 64)
Query Neighborhood Hits	138	Target Neighborhood Hits	126	Shared Neighborhood Hits	7
SwissProt Accessions	Q924W7, Q78H54, Q8K2P3, Q924W8	Gene names	St5, Dennd2b
Domain Architecture	No domain graphic available
Description	Suppression of tumorigenicity 5 (DENN domain-containing protein 2B).

ST5_HUMAN
NC score	0.014568 (rank : 84)	θ value	1.06291 (rank : 68)
Query Neighborhood Hits	138	Target Neighborhood Hits	151	Shared Neighborhood Hits	7
SwissProt Accessions	P78524, P78523, Q16492, Q7KYY2, Q7KZ12, Q8NE12, Q9BQQ6	Gene names	ST5, DENND2B, HTS1
Domain Architecture	No domain graphic available
Description	Suppression of tumorigenicity 5 (HeLa tumor suppression 1) (DENN domain-containing protein 2B).

LETM1_MOUSE
NC score	0.014122 (rank : 85)	θ value	3.0926 (rank : 89)
Query Neighborhood Hits	138	Target Neighborhood Hits	240	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Z2I0, Q5PQC5, Q7TMK8, Q80ZX6, Q8CGJ3, Q8K5E5	Gene names	Letm1
Domain Architecture	No domain graphic available
Description	Leucine zipper-EF-hand-containing transmembrane protein 1, mitochondrial precursor.

YBOX2_HUMAN
NC score	0.013052 (rank : 86)	θ value	2.36792 (rank : 85)
Query Neighborhood Hits	138	Target Neighborhood Hits	50	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y2T7, Q8N4P0	Gene names	YBX2
Domain Architecture	No domain graphic available
Description	Y-box-binding protein 2 (Germ cell-specific Y-box-binding protein) (Contrin) (MSY2 homolog).

NSMA2_HUMAN
NC score	0.012845 (rank : 87)	θ value	2.36792 (rank : 83)
Query Neighborhood Hits	138	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NY59	Gene names	SMPD3
Domain Architecture	No domain graphic available
Description	Sphingomyelin phosphodiesterase 3 (EC 3.1.4.12) (Neutral sphingomyelinase 2) (Neutral sphingomyelinase II) (nSMase2) (nSMase- 2).

FHOD1_MOUSE
NC score	0.012340 (rank : 88)	θ value	1.38821 (rank : 71)
Query Neighborhood Hits	138	Target Neighborhood Hits	217	Shared Neighborhood Hits	12
SwissProt Accessions	Q6P9Q4, Q8BMK2	Gene names	Fhod1, Fhos1
Domain Architecture	No domain graphic available
Description	FH1/FH2 domain-containing protein (Formin homolog overexpressed in spleen) (FHOS) (Formin homology 2 domain-containing protein 1).

EP400_HUMAN
NC score	0.012055 (rank : 89)	θ value	1.38821 (rank : 70)
Query Neighborhood Hits	138	Target Neighborhood Hits	556	Shared Neighborhood Hits	18
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

ABCF1_HUMAN
NC score	0.011825 (rank : 90)	θ value	1.81305 (rank : 72)
Query Neighborhood Hits	138	Target Neighborhood Hits	343	Shared Neighborhood Hits	9
SwissProt Accessions	Q8NE71, O14897, Q69YP6	Gene names	ABCF1, ABC50
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 1 (ATP-binding cassette 50) (TNF-alpha-stimulated ABC protein).

MCM5_MOUSE
NC score	0.011812 (rank : 91)	θ value	3.0926 (rank : 90)
Query Neighborhood Hits	138	Target Neighborhood Hits	36	Shared Neighborhood Hits	6
SwissProt Accessions	P49718	Gene names	Mcm5, Cdc46, Mcmd5
Domain Architecture
Description	DNA replication licensing factor MCM5 (CDC46 homolog) (P1-CDC46).

ABCF1_MOUSE
NC score	0.011737 (rank : 92)	θ value	6.88961 (rank : 114)
Query Neighborhood Hits	138	Target Neighborhood Hits	321	Shared Neighborhood Hits	10
SwissProt Accessions	Q6P542, Q6NV71	Gene names	Abcf1
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 1.

RD23B_MOUSE
NC score	0.011705 (rank : 93)	θ value	3.0926 (rank : 93)
Query Neighborhood Hits	138	Target Neighborhood Hits	189	Shared Neighborhood Hits	10
SwissProt Accessions	P54728	Gene names	Rad23b, Mhr23b
Domain Architecture
Description	UV excision repair protein RAD23 homolog B (mHR23B) (XP-C repair- complementing complex 58 kDa protein) (p58).

PCLO_MOUSE
NC score	0.011162 (rank : 94)	θ value	2.36792 (rank : 84)
Query Neighborhood Hits	138	Target Neighborhood Hits	2275	Shared Neighborhood Hits	41
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

MCM5_HUMAN
NC score	0.011051 (rank : 95)	θ value	4.03905 (rank : 104)
Query Neighborhood Hits	138	Target Neighborhood Hits	37	Shared Neighborhood Hits	6
SwissProt Accessions	P33992, O60785, Q14578, Q9BTJ4, Q9BWL8	Gene names	MCM5, CDC46
Domain Architecture
Description	DNA replication licensing factor MCM5 (CDC46 homolog) (P1-CDC46).

LSD1_MOUSE
NC score	0.011007 (rank : 96)	θ value	8.99809 (rank : 132)
Query Neighborhood Hits	138	Target Neighborhood Hits	224	Shared Neighborhood Hits	11
SwissProt Accessions	Q6ZQ88, Q6PB53, Q8VEA1	Gene names	Aof2, Kiaa0601, Lsd1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

MAP4_HUMAN
NC score	0.010878 (rank : 97)	θ value	8.99809 (rank : 133)
Query Neighborhood Hits	138	Target Neighborhood Hits	428	Shared Neighborhood Hits	16
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

CND1_HUMAN
NC score	0.010499 (rank : 98)	θ value	3.0926 (rank : 87)
Query Neighborhood Hits	138	Target Neighborhood Hits	37	Shared Neighborhood Hits	3
SwissProt Accessions	Q15021, Q8N6U3	Gene names	NCAPD2, CAPD2, CNAP1, KIAA0159
Domain Architecture
Description	Condensin complex subunit 1 (Non-SMC condensin I complex subunit D2) (Chromosome condensation-related SMC-associated protein 1) (Chromosome-associated protein D2) (hCAP-D2) (XCAP-D2 homolog).

YBOX2_MOUSE
NC score	0.010455 (rank : 99)	θ value	6.88961 (rank : 125)
Query Neighborhood Hits	138	Target Neighborhood Hits	46	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z2C8, Q5NCW8, Q5NCW9, Q9Z2C7	Gene names	Ybx2, Msy2
Domain Architecture	No domain graphic available
Description	Y-box-binding protein 2 (Germ cell-specific Y-box-binding protein) (FRGY2 homolog).

OGFR_HUMAN
NC score	0.010411 (rank : 100)	θ value	0.62314 (rank : 63)
Query Neighborhood Hits	138	Target Neighborhood Hits	1582	Shared Neighborhood Hits	40
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

MKL2_HUMAN
NC score	0.010370 (rank : 101)	θ value	1.81305 (rank : 76)
Query Neighborhood Hits	138	Target Neighborhood Hits	274	Shared Neighborhood Hits	14
SwissProt Accessions	Q9ULH7, Q68CT1, Q6UB16, Q86WW2, Q8N226	Gene names	MKL2, KIAA1243, MRTFB
Domain Architecture
Description	MKL/myocardin-like protein 2 (Myocardin-related transcription factor B) (MRTF-B) (Megakaryoblastic leukemia 2).

EP400_MOUSE
NC score	0.009996 (rank : 102)	θ value	2.36792 (rank : 79)
Query Neighborhood Hits	138	Target Neighborhood Hits	592	Shared Neighborhood Hits	16
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

LBXCO_HUMAN
NC score	0.009517 (rank : 103)	θ value	3.0926 (rank : 88)
Query Neighborhood Hits	138	Target Neighborhood Hits	167	Shared Neighborhood Hits	8
SwissProt Accessions	P84550	Gene names	LBXCOR1
Domain Architecture	No domain graphic available
Description	Ladybird homeobox corepressor 1.

AFF4_MOUSE
NC score	0.009055 (rank : 104)	θ value	4.03905 (rank : 100)
Query Neighborhood Hits	138	Target Neighborhood Hits	581	Shared Neighborhood Hits	16
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

DYHC_MOUSE
NC score	0.009036 (rank : 105)	θ value	6.88961 (rank : 117)
Query Neighborhood Hits	138	Target Neighborhood Hits	729	Shared Neighborhood Hits	23
SwissProt Accessions	Q9JHU4	Gene names	Dync1h1, Dnch1, Dnchc1
Domain Architecture
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

DYHC_HUMAN
NC score	0.008982 (rank : 106)	θ value	6.88961 (rank : 116)
Query Neighborhood Hits	138	Target Neighborhood Hits	733	Shared Neighborhood Hits	23
SwissProt Accessions	Q14204, Q6DKQ7, Q8WU28, Q92814, Q9Y4G5	Gene names	DYNC1H1, DNCH1, DNECL, KIAA0325
Domain Architecture	No domain graphic available
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

HRX_HUMAN
NC score	0.007959 (rank : 107)	θ value	2.36792 (rank : 81)
Query Neighborhood Hits	138	Target Neighborhood Hits	825	Shared Neighborhood Hits	24
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

OLIG1_HUMAN
NC score	0.007924 (rank : 108)	θ value	3.0926 (rank : 91)
Query Neighborhood Hits	138	Target Neighborhood Hits	85	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TAK6, Q7RTS0	Gene names	OLIG1
Domain Architecture
Description	Oligodendrocyte transcription factor 1 (Oligo1).

EAN57_HUMAN
NC score	0.007762 (rank : 109)	θ value	8.99809 (rank : 128)
Query Neighborhood Hits	138	Target Neighborhood Hits	62	Shared Neighborhood Hits	8
SwissProt Accessions	O43247, Q6ICF2, Q9Y4V8	Gene names	EAN57
Domain Architecture	No domain graphic available
Description	Protein EAN57.

GSHB_MOUSE
NC score	0.007646 (rank : 110)	θ value	6.88961 (rank : 119)
Query Neighborhood Hits	138	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	P51855	Gene names	Gss
Domain Architecture
Description	Glutathione synthetase (EC 6.3.2.3) (Glutathione synthase) (GSH synthetase) (GSH-S).

BPAEA_HUMAN
NC score	0.007566 (rank : 111)	θ value	5.27518 (rank : 107)
Query Neighborhood Hits	138	Target Neighborhood Hits	1369	Shared Neighborhood Hits	27
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CJ108_HUMAN
NC score	0.007093 (rank : 112)	θ value	8.99809 (rank : 126)
Query Neighborhood Hits	138	Target Neighborhood Hits	165	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N8Z3	Gene names	C10orf108
Domain Architecture	No domain graphic available
Description	Putative uncharacterized protein C10orf108.

BSN_MOUSE
NC score	0.007043 (rank : 113)	θ value	3.0926 (rank : 86)
Query Neighborhood Hits	138	Target Neighborhood Hits	2057	Shared Neighborhood Hits	36
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

ZDHC8_HUMAN
NC score	0.006276 (rank : 114)	θ value	1.81305 (rank : 77)
Query Neighborhood Hits	138	Target Neighborhood Hits	234	Shared Neighborhood Hits	9
SwissProt Accessions	Q9ULC8, Q6ICL1, Q6ZNF5, Q7Z6L9	Gene names	ZDHHC8, KIAA1292, ZDHHCL1, ZNF378
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC8 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 8) (DHHC-8) (Zinc finger protein 378).

CX039_HUMAN
NC score	0.006249 (rank : 115)	θ value	8.99809 (rank : 127)
Query Neighborhood Hits	138	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	Q6PEV8, Q8WVP6, Q96AV3	Gene names	CXorf39
Domain Architecture	No domain graphic available
Description	Uncharacterized protein CXorf39.

KS6C1_HUMAN
NC score	0.006224 (rank : 116)	θ value	8.99809 (rank : 131)
Query Neighborhood Hits	138	Target Neighborhood Hits	682	Shared Neighborhood Hits	12
SwissProt Accessions	Q96S38, Q8TDD3, Q9NSF4, Q9UL66	Gene names	RPS6KC1, RPK118
Domain Architecture	No domain graphic available
Description	Ribosomal protein S6 kinase delta-1 (EC 2.7.11.1) (52 kDa ribosomal protein S6 kinase) (Ribosomal S6 kinase-like protein with two PSK domains 118 kDa protein) (SPHK1-binding protein).

BPAEA_MOUSE
NC score	0.006163 (rank : 117)	θ value	4.03905 (rank : 102)
Query Neighborhood Hits	138	Target Neighborhood Hits	1480	Shared Neighborhood Hits	29
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

TF3C2_HUMAN
NC score	0.005793 (rank : 118)	θ value	8.99809 (rank : 136)
Query Neighborhood Hits	138	Target Neighborhood Hits	168	Shared Neighborhood Hits	5
SwissProt Accessions	Q8WUA4, Q16632, Q9BWI7	Gene names	GTF3C2, KIAA0011
Domain Architecture
Description	General transcription factor 3C polypeptide 2 (Transcription factor IIIC-subunit beta) (TF3C-beta) (TFIIIC 110 kDa subunit) (TFIIIC110).

RECQ5_HUMAN
NC score	0.005566 (rank : 119)	θ value	5.27518 (rank : 112)
Query Neighborhood Hits	138	Target Neighborhood Hits	390	Shared Neighborhood Hits	16
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

TACC3_HUMAN
NC score	0.005093 (rank : 120)	θ value	3.0926 (rank : 99)
Query Neighborhood Hits	138	Target Neighborhood Hits	779	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

THAP4_HUMAN
NC score	0.004643 (rank : 121)	θ value	8.99809 (rank : 137)
Query Neighborhood Hits	138	Target Neighborhood Hits	92	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WY91, Q53NU7, Q6GRN0, Q6IPJ3, Q9NW26, Q9Y325	Gene names	THAP4
Domain Architecture
Description	THAP domain-containing protein 4.

IMMT_HUMAN
NC score	0.004203 (rank : 122)	θ value	8.99809 (rank : 129)
Query Neighborhood Hits	138	Target Neighborhood Hits	494	Shared Neighborhood Hits	13
SwissProt Accessions	Q16891, Q14539, Q15092, Q68D41, Q69HW5, Q6IBL0, Q7Z3X1, Q8TAJ5, Q9P0V2	Gene names	IMMT, HMP, PIG4
Domain Architecture	No domain graphic available
Description	Mitochondrial inner membrane protein (Mitofilin) (p87/89) (Proliferation-inducing gene 4 protein).

ZFHX2_HUMAN
NC score	0.004100 (rank : 123)	θ value	1.81305 (rank : 78)
Query Neighborhood Hits	138	Target Neighborhood Hits	1178	Shared Neighborhood Hits	12
SwissProt Accessions	Q9C0A1	Gene names	ZFHX2, KIAA1762
Domain Architecture
Description	Zinc finger homeobox protein 2.

BPA1_MOUSE
NC score	0.002947 (rank : 124)	θ value	4.03905 (rank : 101)
Query Neighborhood Hits	138	Target Neighborhood Hits	1477	Shared Neighborhood Hits	21
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

BRE1B_HUMAN
NC score	0.002835 (rank : 125)	θ value	6.88961 (rank : 115)
Query Neighborhood Hits	138	Target Neighborhood Hits	1040	Shared Neighborhood Hits	21
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

DIAP1_MOUSE
NC score	0.002696 (rank : 126)	θ value	5.27518 (rank : 109)
Query Neighborhood Hits	138	Target Neighborhood Hits	839	Shared Neighborhood Hits	19
SwissProt Accessions	O08808	Gene names	Diaph1, Diap1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) (mDIA1) (p140mDIA).

RAVR2_HUMAN
NC score	0.002500 (rank : 127)	θ value	8.99809 (rank : 134)
Query Neighborhood Hits	138	Target Neighborhood Hits	144	Shared Neighborhood Hits	4
SwissProt Accessions	Q9HCJ3, Q6P141, Q9NPV7	Gene names	RAVER2, KIAA1579
Domain Architecture	No domain graphic available
Description	Ribonucleoprotein PTB-binding 2 (Protein raver-2).

FOXL1_HUMAN
NC score	0.002446 (rank : 128)	θ value	2.36792 (rank : 80)
Query Neighborhood Hits	138	Target Neighborhood Hits	114	Shared Neighborhood Hits	5
SwissProt Accessions	Q12952, Q9H242	Gene names	FOXL1, FKHL11, FREAC7
Domain Architecture
Description	Forkhead box protein L1 (Forkhead-related protein FKHL11) (Forkhead- related transcription factor 7) (FREAC-7).

CO6A2_HUMAN
NC score	0.002078 (rank : 129)	θ value	5.27518 (rank : 108)
Query Neighborhood Hits	138	Target Neighborhood Hits	249	Shared Neighborhood Hits	7
SwissProt Accessions	P12110, Q13909, Q13910, Q13911, Q14049, Q16259, Q16597, Q9UML3	Gene names	COL6A2
Domain Architecture
Description	Collagen alpha-2(VI) chain precursor.

HMMR_HUMAN
NC score	0.001848 (rank : 130)	θ value	4.03905 (rank : 103)
Query Neighborhood Hits	138	Target Neighborhood Hits	1082	Shared Neighborhood Hits	18
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

PDE9A_HUMAN
NC score	0.001796 (rank : 131)	θ value	6.88961 (rank : 122)
Query Neighborhood Hits	138	Target Neighborhood Hits	93	Shared Neighborhood Hits	4
SwissProt Accessions	O76083, O75490, O75491, O95225, Q86SF7, Q86SI6, Q86SJ3, Q86WN3, Q86WN4, Q86WN5, Q86WN6, Q86WN7, Q86WN8, Q86WN9, Q86WP0	Gene names	PDE9A
Domain Architecture
Description	High-affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A (EC 3.1.4.35).

NFH_MOUSE
NC score	0.001782 (rank : 132)	θ value	0.813845 (rank : 66)
Query Neighborhood Hits	138	Target Neighborhood Hits	2247	Shared Neighborhood Hits	45
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

RGS3_HUMAN
NC score	0.001209 (rank : 133)	θ value	4.03905 (rank : 105)
Query Neighborhood Hits	138	Target Neighborhood Hits	1375	Shared Neighborhood Hits	25
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

MACF1_HUMAN
NC score	0.001209 (rank : 134)	θ value	6.88961 (rank : 121)
Query Neighborhood Hits	138	Target Neighborhood Hits	1341	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

SUHW3_MOUSE
NC score	-0.000601 (rank : 135)	θ value	3.0926 (rank : 98)
Query Neighborhood Hits	138	Target Neighborhood Hits	697	Shared Neighborhood Hits	4
SwissProt Accessions	Q6P3Y5, Q6ZPM2, Q8K145	Gene names	Suhw3, Kiaa1584
Domain Architecture	No domain graphic available
Description	Suppressor of hairy wing homolog 3.

EHMT2_HUMAN
NC score	-0.001446 (rank : 136)	θ value	6.88961 (rank : 118)
Query Neighborhood Hits	138	Target Neighborhood Hits	498	Shared Neighborhood Hits	7
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

TTK_MOUSE
NC score	-0.001729 (rank : 137)	θ value	5.27518 (rank : 113)
Query Neighborhood Hits	138	Target Neighborhood Hits	803	Shared Neighborhood Hits	9
SwissProt Accessions	P35761	Gene names	Ttk, Esk
Domain Architecture
Description	Dual specificity protein kinase TTK (EC 2.7.12.1) (ESK) (PYT).

M3K6_HUMAN
NC score	-0.001959 (rank : 138)	θ value	1.81305 (rank : 74)
Query Neighborhood Hits	138	Target Neighborhood Hits	889	Shared Neighborhood Hits	10
SwissProt Accessions	O95382	Gene names	MAP3K6, MAPKKK6
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 6 (EC 2.7.11.25).

LAP4_MOUSE
NC score	-0.002074 (rank : 139)	θ value	6.88961 (rank : 120)
Query Neighborhood Hits	138	Target Neighborhood Hits	590	Shared Neighborhood Hits	7
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

MK15_HUMAN
NC score	-0.002079 (rank : 140)	θ value	0.365318 (rank : 60)
Query Neighborhood Hits	138	Target Neighborhood Hits	1038	Shared Neighborhood Hits	18
SwissProt Accessions	Q8TD08, Q2TCF9, Q8N362	Gene names	MAPK15, ERK8
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase 15 (EC 2.7.11.24) (Extracellular signal-regulated kinase 8).

M3K15_HUMAN
NC score	-0.002084 (rank : 141)	θ value	1.81305 (rank : 73)
Query Neighborhood Hits	138	Target Neighborhood Hits	914	Shared Neighborhood Hits	13
SwissProt Accessions	Q6ZN16, Q5JPR4, Q6ZMV3	Gene names	MAP3K15
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 15 (EC 2.7.11.25) (MAPK/ERK kinase kinase 15) (MEK kinase 15) (MEKK 15).

MAST4_HUMAN
NC score	-0.002236 (rank : 142)	θ value	1.81305 (rank : 75)
Query Neighborhood Hits	138	Target Neighborhood Hits	1804	Shared Neighborhood Hits	31
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

TTK_HUMAN
NC score	-0.002525 (rank : 143)	θ value	8.99809 (rank : 138)
Query Neighborhood Hits	138	Target Neighborhood Hits	816	Shared Neighborhood Hits	9
SwissProt Accessions	P33981	Gene names	TTK, MPS1L1
Domain Architecture
Description	Dual specificity protein kinase TTK (EC 2.7.12.1) (Phosphotyrosine picked threonine-protein kinase) (PYT).

KLF12_MOUSE
NC score	-0.005302 (rank : 144)	θ value	5.27518 (rank : 111)
Query Neighborhood Hits	138	Target Neighborhood Hits	721	Shared Neighborhood Hits	6
SwissProt Accessions	O35738	Gene names	Klf12, Ap2rep
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 12 (Transcriptional repressor AP-2rep).