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Network neighborhood for query Sequence : SPN1_MOUSE

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SPN1_MOUSE
SwissProt Accessions	Q80W37	Gene names	Snupn, Rnut1
Domain Architecture	No domain graphic available
Description	Snurportin-1 (RNA U transporter 1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SPN1_MOUSE
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	12	Target Neighborhood Hits	12	Shared Neighborhood Hits	12
SwissProt Accessions	Q80W37	Gene names	Snupn, Rnut1
Domain Architecture	No domain graphic available
Description	Snurportin-1 (RNA U transporter 1).

SPN1_HUMAN
θ value	3.82926e-184 (rank : 2)	NC score	0.994983 (rank : 2)
Query Neighborhood Hits	12	Target Neighborhood Hits	11	Shared Neighborhood Hits	7
SwissProt Accessions	O95149	Gene names	SNUPN, RNUT1, SPN1
Domain Architecture	No domain graphic available
Description	Snurportin-1 (RNA U transporter 1).

SPAST_MOUSE
θ value	0.21417 (rank : 3)	NC score	0.038567 (rank : 5)
Query Neighborhood Hits	12	Target Neighborhood Hits	138	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QYY8, Q6ZPY6, Q80VE0, Q9CVK0	Gene names	Spast, Kiaa1083, Spg4
Domain Architecture	No domain graphic available
Description	Spastin.

RNF8_HUMAN
θ value	0.365318 (rank : 4)	NC score	0.041700 (rank : 4)
Query Neighborhood Hits	12	Target Neighborhood Hits	622	Shared Neighborhood Hits	3
SwissProt Accessions	O76064	Gene names	RNF8, KIAA0646
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8).

SPAST_HUMAN
θ value	0.47712 (rank : 5)	NC score	0.036838 (rank : 6)
Query Neighborhood Hits	12	Target Neighborhood Hits	100	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UBP0, Q9UPR9	Gene names	SPAST, KIAA1083, SPG4
Domain Architecture
Description	Spastin.

MCE1_HUMAN
θ value	1.81305 (rank : 6)	NC score	0.046918 (rank : 3)
Query Neighborhood Hits	12	Target Neighborhood Hits	34	Shared Neighborhood Hits	3
SwissProt Accessions	O60942, O43483, O60257, O60351	Gene names	RNGTT, CAP1A
Domain Architecture
Description	mRNA capping enzyme (HCE) (HCAP1) [Includes: Polynucleotide 5'- triphosphatase (EC 3.1.3.33) (mRNA 5'-triphosphatase) (TPase); mRNA guanylyltransferase (EC 2.7.7.50) (GTP--RNA guanylyltransferase) (GTase)].

RNF8_MOUSE
θ value	2.36792 (rank : 7)	NC score	0.035973 (rank : 7)
Query Neighborhood Hits	12	Target Neighborhood Hits	618	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VC56, Q9JK13	Gene names	Rnf8
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8) (AIP37) (ActA-interacting protein 37) (LaXp180).

SUHW1_HUMAN
θ value	4.03905 (rank : 8)	NC score	0.014212 (rank : 11)
Query Neighborhood Hits	12	Target Neighborhood Hits	648	Shared Neighborhood Hits	4
SwissProt Accessions	P59817	Gene names	SUHW1
Domain Architecture	No domain graphic available
Description	Suppressor of hairy wing homolog 1 (3'OY11.1).

SUHW2_HUMAN
θ value	4.03905 (rank : 9)	NC score	0.011320 (rank : 12)
Query Neighborhood Hits	12	Target Neighborhood Hits	683	Shared Neighborhood Hits	4
SwissProt Accessions	Q86YH2	Gene names	SUHW2, ZNF632
Domain Architecture	No domain graphic available
Description	Suppressor of hairy wing homolog 2 (5'OY11.1) (Zinc finger protein 632).

F10C1_HUMAN
θ value	5.27518 (rank : 10)	NC score	0.035537 (rank : 8)
Query Neighborhood Hits	12	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	Q70Z53, Q70Z49, Q70Z50, Q70Z51, Q70Z52, Q8N293, Q8WVH5, Q96JQ8	Gene names	FRA10AC1, C10orf4
Domain Architecture	No domain graphic available
Description	Protein FRA10AC1.

TOP1_MOUSE
θ value	5.27518 (rank : 11)	NC score	0.018107 (rank : 10)
Query Neighborhood Hits	12	Target Neighborhood Hits	213	Shared Neighborhood Hits	2
SwissProt Accessions	Q04750	Gene names	Top1, Top-1
Domain Architecture
Description	DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I).

CNGB1_HUMAN
θ value	6.88961 (rank : 12)	NC score	0.020370 (rank : 9)
Query Neighborhood Hits	12	Target Neighborhood Hits	222	Shared Neighborhood Hits	3
SwissProt Accessions	Q14028, Q14029	Gene names	CNGB1, CNCG4
Domain Architecture
Description	Cyclic nucleotide-gated cation channel 4 (CNG channel 4) (CNG-4) (CNG4) (Cyclic nucleotide-gated cation channel modulatory subunit).

Hits sorted by NC score

SPN1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	12	Target Neighborhood Hits	12	Shared Neighborhood Hits	12
SwissProt Accessions	Q80W37	Gene names	Snupn, Rnut1
Domain Architecture	No domain graphic available
Description	Snurportin-1 (RNA U transporter 1).

SPN1_HUMAN
NC score	0.994983 (rank : 2)	θ value	3.82926e-184 (rank : 2)
Query Neighborhood Hits	12	Target Neighborhood Hits	11	Shared Neighborhood Hits	7
SwissProt Accessions	O95149	Gene names	SNUPN, RNUT1, SPN1
Domain Architecture	No domain graphic available
Description	Snurportin-1 (RNA U transporter 1).

MCE1_HUMAN
NC score	0.046918 (rank : 3)	θ value	1.81305 (rank : 6)
Query Neighborhood Hits	12	Target Neighborhood Hits	34	Shared Neighborhood Hits	3
SwissProt Accessions	O60942, O43483, O60257, O60351	Gene names	RNGTT, CAP1A
Domain Architecture
Description	mRNA capping enzyme (HCE) (HCAP1) [Includes: Polynucleotide 5'- triphosphatase (EC 3.1.3.33) (mRNA 5'-triphosphatase) (TPase); mRNA guanylyltransferase (EC 2.7.7.50) (GTP--RNA guanylyltransferase) (GTase)].

RNF8_HUMAN
NC score	0.041700 (rank : 4)	θ value	0.365318 (rank : 4)
Query Neighborhood Hits	12	Target Neighborhood Hits	622	Shared Neighborhood Hits	3
SwissProt Accessions	O76064	Gene names	RNF8, KIAA0646
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8).

SPAST_MOUSE
NC score	0.038567 (rank : 5)	θ value	0.21417 (rank : 3)
Query Neighborhood Hits	12	Target Neighborhood Hits	138	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QYY8, Q6ZPY6, Q80VE0, Q9CVK0	Gene names	Spast, Kiaa1083, Spg4
Domain Architecture	No domain graphic available
Description	Spastin.

SPAST_HUMAN
NC score	0.036838 (rank : 6)	θ value	0.47712 (rank : 5)
Query Neighborhood Hits	12	Target Neighborhood Hits	100	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UBP0, Q9UPR9	Gene names	SPAST, KIAA1083, SPG4
Domain Architecture
Description	Spastin.

RNF8_MOUSE
NC score	0.035973 (rank : 7)	θ value	2.36792 (rank : 7)
Query Neighborhood Hits	12	Target Neighborhood Hits	618	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VC56, Q9JK13	Gene names	Rnf8
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8) (AIP37) (ActA-interacting protein 37) (LaXp180).

F10C1_HUMAN
NC score	0.035537 (rank : 8)	θ value	5.27518 (rank : 10)
Query Neighborhood Hits	12	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	Q70Z53, Q70Z49, Q70Z50, Q70Z51, Q70Z52, Q8N293, Q8WVH5, Q96JQ8	Gene names	FRA10AC1, C10orf4
Domain Architecture	No domain graphic available
Description	Protein FRA10AC1.

CNGB1_HUMAN
NC score	0.020370 (rank : 9)	θ value	6.88961 (rank : 12)
Query Neighborhood Hits	12	Target Neighborhood Hits	222	Shared Neighborhood Hits	3
SwissProt Accessions	Q14028, Q14029	Gene names	CNGB1, CNCG4
Domain Architecture
Description	Cyclic nucleotide-gated cation channel 4 (CNG channel 4) (CNG-4) (CNG4) (Cyclic nucleotide-gated cation channel modulatory subunit).

TOP1_MOUSE
NC score	0.018107 (rank : 10)	θ value	5.27518 (rank : 11)
Query Neighborhood Hits	12	Target Neighborhood Hits	213	Shared Neighborhood Hits	2
SwissProt Accessions	Q04750	Gene names	Top1, Top-1
Domain Architecture
Description	DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I).

SUHW1_HUMAN
NC score	0.014212 (rank : 11)	θ value	4.03905 (rank : 8)
Query Neighborhood Hits	12	Target Neighborhood Hits	648	Shared Neighborhood Hits	4
SwissProt Accessions	P59817	Gene names	SUHW1
Domain Architecture	No domain graphic available
Description	Suppressor of hairy wing homolog 1 (3'OY11.1).

SUHW2_HUMAN
NC score	0.011320 (rank : 12)	θ value	4.03905 (rank : 9)
Query Neighborhood Hits	12	Target Neighborhood Hits	683	Shared Neighborhood Hits	4
SwissProt Accessions	Q86YH2	Gene names	SUHW2, ZNF632
Domain Architecture	No domain graphic available
Description	Suppressor of hairy wing homolog 2 (5'OY11.1) (Zinc finger protein 632).