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Network neighborhood for query Sequence : SPG20_MOUSE

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SPG20_MOUSE
SwissProt Accessions	Q8R1X6, Q6ZQ87, Q8BJD3, Q8BM37, Q8BZ63	Gene names	Spg20, Kiaa0610
Domain Architecture	No domain graphic available
Description	Spartin.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SPG20_HUMAN
θ value	0 (rank : 1)	NC score	0.988929 (rank : 2)
Query Neighborhood Hits	33	Target Neighborhood Hits	28	Shared Neighborhood Hits	9
SwissProt Accessions	Q8N0X7, O60349, Q86Y67, Q9H1T2, Q9H1T3	Gene names	SPG20, KIAA0610, TAHCCP1
Domain Architecture	No domain graphic available
Description	Spartin (Trans-activated by hepatitis C virus core protein 1).

SPG20_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	33	Target Neighborhood Hits	33	Shared Neighborhood Hits	33
SwissProt Accessions	Q8R1X6, Q6ZQ87, Q8BJD3, Q8BM37, Q8BZ63	Gene names	Spg20, Kiaa0610
Domain Architecture	No domain graphic available
Description	Spartin.

SPAST_MOUSE
θ value	4.0297e-08 (rank : 3)	NC score	0.152692 (rank : 3)
Query Neighborhood Hits	33	Target Neighborhood Hits	138	Shared Neighborhood Hits	5
SwissProt Accessions	Q9QYY8, Q6ZPY6, Q80VE0, Q9CVK0	Gene names	Spast, Kiaa1083, Spg4
Domain Architecture	No domain graphic available
Description	Spastin.

SPAST_HUMAN
θ value	5.81887e-07 (rank : 4)	NC score	0.144415 (rank : 4)
Query Neighborhood Hits	33	Target Neighborhood Hits	100	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UBP0, Q9UPR9	Gene names	SPAST, KIAA1083, SPG4
Domain Architecture
Description	Spastin.

MTSS1_HUMAN
θ value	0.21417 (rank : 5)	NC score	0.066034 (rank : 5)
Query Neighborhood Hits	33	Target Neighborhood Hits	504	Shared Neighborhood Hits	7
SwissProt Accessions	O43312, Q8TCA2, Q96RX2	Gene names	MTSS1, KIAA0429, MIM
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein) (Metastasis suppressor YGL-1).

GRIN1_HUMAN
θ value	0.365318 (rank : 6)	NC score	0.036380 (rank : 11)
Query Neighborhood Hits	33	Target Neighborhood Hits	681	Shared Neighborhood Hits	4
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

MTSS1_MOUSE
θ value	0.813845 (rank : 7)	NC score	0.057220 (rank : 6)
Query Neighborhood Hits	33	Target Neighborhood Hits	592	Shared Neighborhood Hits	7
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

OGFR_HUMAN
θ value	1.06291 (rank : 8)	NC score	0.023388 (rank : 20)
Query Neighborhood Hits	33	Target Neighborhood Hits	1582	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

RECQ4_MOUSE
θ value	1.38821 (rank : 9)	NC score	0.023790 (rank : 19)
Query Neighborhood Hits	33	Target Neighborhood Hits	206	Shared Neighborhood Hits	3
SwissProt Accessions	Q75NR7, Q76MT1, Q99PV9	Gene names	Recql4, Recq4
Domain Architecture	No domain graphic available
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4).

RPTN_MOUSE
θ value	1.38821 (rank : 10)	NC score	0.016550 (rank : 23)
Query Neighborhood Hits	33	Target Neighborhood Hits	650	Shared Neighborhood Hits	4
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

SEBP2_HUMAN
θ value	1.38821 (rank : 11)	NC score	0.039551 (rank : 10)
Query Neighborhood Hits	33	Target Neighborhood Hits	88	Shared Neighborhood Hits	3
SwissProt Accessions	Q96T21, Q8IYC0	Gene names	SECISBP2, SBP2
Domain Architecture
Description	SECIS-binding protein 2 (Selenocysteine insertion sequence-binding protein 2).

SNP29_MOUSE
θ value	1.38821 (rank : 12)	NC score	0.041248 (rank : 9)
Query Neighborhood Hits	33	Target Neighborhood Hits	65	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ERB0, Q3UGN0, Q9DBC5	Gene names	Snap29
Domain Architecture
Description	Synaptosomal-associated protein 29 (SNAP-29) (Vesicle-membrane fusion protein SNAP-29) (Soluble 29 kDa NSF attachment protein) (Golgi SNARE of 32 kDa) (Gs32).

NACAM_MOUSE
θ value	1.81305 (rank : 13)	NC score	0.027796 (rank : 15)
Query Neighborhood Hits	33	Target Neighborhood Hits	1866	Shared Neighborhood Hits	11
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

PASK_HUMAN
θ value	1.81305 (rank : 14)	NC score	0.005563 (rank : 34)
Query Neighborhood Hits	33	Target Neighborhood Hits	857	Shared Neighborhood Hits	3
SwissProt Accessions	Q96RG2, Q86XH6, Q99763, Q9UFR7	Gene names	PASK, KIAA0135
Domain Architecture
Description	PAS domain-containing serine/threonine-protein kinase (EC 2.7.11.1) (PAS-kinase) (PASKIN) (hPASK).

TRBM_HUMAN
θ value	1.81305 (rank : 15)	NC score	0.013529 (rank : 25)
Query Neighborhood Hits	33	Target Neighborhood Hits	339	Shared Neighborhood Hits	3
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

GCC2_MOUSE
θ value	2.36792 (rank : 16)	NC score	0.012171 (rank : 26)
Query Neighborhood Hits	33	Target Neighborhood Hits	1619	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

MUC1_HUMAN
θ value	2.36792 (rank : 17)	NC score	0.014971 (rank : 24)
Query Neighborhood Hits	33	Target Neighborhood Hits	975	Shared Neighborhood Hits	6
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

JPH2_MOUSE
θ value	3.0926 (rank : 18)	NC score	0.028661 (rank : 14)
Query Neighborhood Hits	33	Target Neighborhood Hits	279	Shared Neighborhood Hits	7
SwissProt Accessions	Q9ET78, Q9ET79	Gene names	Jph2, Jp2
Domain Architecture	No domain graphic available
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

OCLN_HUMAN
θ value	3.0926 (rank : 19)	NC score	0.036279 (rank : 12)
Query Neighborhood Hits	33	Target Neighborhood Hits	131	Shared Neighborhood Hits	4
SwissProt Accessions	Q16625, Q8N6K1	Gene names	OCLN
Domain Architecture
Description	Occludin.

PDZD2_HUMAN
θ value	3.0926 (rank : 20)	NC score	0.017266 (rank : 22)
Query Neighborhood Hits	33	Target Neighborhood Hits	772	Shared Neighborhood Hits	5
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

CP4F3_MOUSE
θ value	4.03905 (rank : 21)	NC score	0.007365 (rank : 33)
Query Neighborhood Hits	33	Target Neighborhood Hits	111	Shared Neighborhood Hits	2
SwissProt Accessions	Q99N16, Q9D8N4	Gene names	Cyp4f3, Cyp4f18
Domain Architecture	No domain graphic available
Description	Cytochrome P450 4F3 (EC 1.14.13.30) (CYPIVF3) (Leukotriene-B(4) omega- hydroxylase) (Leukotriene-B(4) 20-monooxygenase) (Cytochrome P450-LTB- omega).

DOK2_MOUSE
θ value	4.03905 (rank : 22)	NC score	0.021129 (rank : 21)
Query Neighborhood Hits	33	Target Neighborhood Hits	244	Shared Neighborhood Hits	6
SwissProt Accessions	O70469, O70272, Q99KL1	Gene names	Dok2, Frip
Domain Architecture
Description	Docking protein 2 (Downstream of tyrosine kinase 2) (p56(dok-2)) (Dok- related protein) (Dok-R) (IL-four receptor-interacting protein) (FRIP).

NELL2_MOUSE
θ value	4.03905 (rank : 23)	NC score	0.008128 (rank : 31)
Query Neighborhood Hits	33	Target Neighborhood Hits	436	Shared Neighborhood Hits	3
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

PSIP1_HUMAN
θ value	4.03905 (rank : 24)	NC score	0.025982 (rank : 17)
Query Neighborhood Hits	33	Target Neighborhood Hits	341	Shared Neighborhood Hits	3
SwissProt Accessions	O75475, O00256, O95368, Q6P391, Q86YB9, Q9NZI3, Q9UER6	Gene names	PSIP1, DFS70, LEDGF, PSIP2
Domain Architecture	No domain graphic available
Description	PC4 and SFRS1-interacting protein (Lens epithelium-derived growth factor) (Transcriptional coactivator p75/p52) (Dense fine speckles 70 kDa protein) (DFS 70) (CLL-associated antigen KW-7).

PSIP1_MOUSE
θ value	4.03905 (rank : 25)	NC score	0.026796 (rank : 16)
Query Neighborhood Hits	33	Target Neighborhood Hits	313	Shared Neighborhood Hits	4
SwissProt Accessions	Q99JF8, Q3TEJ7, Q3TTD7, Q3UTA1, Q80WQ7, Q99JF7, Q99LR4, Q9CT03	Gene names	Psip1, Ledgf
Domain Architecture	No domain graphic available
Description	PC4 and SFRS1-interacting protein (Lens epithelium-derived growth factor) (mLEDGF).

EDN3_HUMAN
θ value	5.27518 (rank : 26)	NC score	0.024595 (rank : 18)
Query Neighborhood Hits	33	Target Neighborhood Hits	61	Shared Neighborhood Hits	3
SwissProt Accessions	P14138, Q03229	Gene names	EDN3
Domain Architecture
Description	Endothelin-3 precursor (ET-3) (Preproendothelin-3) (PPET3).

PDZD1_MOUSE
θ value	5.27518 (rank : 27)	NC score	0.011896 (rank : 27)
Query Neighborhood Hits	33	Target Neighborhood Hits	191	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JIL4, Q8CDP5, Q8R4G2, Q9CQ72	Gene names	Pdzk1, Cap70, Nherf3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

PITM1_MOUSE
θ value	5.27518 (rank : 28)	NC score	0.011604 (rank : 28)
Query Neighborhood Hits	33	Target Neighborhood Hits	69	Shared Neighborhood Hits	2
SwissProt Accessions	O35954	Gene names	Pitpnm1, Dres9, Mpt1, Nir2, Pitpnm
Domain Architecture	No domain graphic available
Description	Membrane-associated phosphatidylinositol transfer protein 1 (Phosphatidylinositol transfer protein, membrane-associated 1) (PITPnm 1) (Mpt-1) (Pyk2 N-terminal domain-interacting receptor 2) (NIR-2) (Drosophila retinal degeneration B homolog 1) (RdgB1).

CU067_HUMAN
θ value	6.88961 (rank : 29)	NC score	0.030722 (rank : 13)
Query Neighborhood Hits	33	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	P58512	Gene names	C21orf67
Domain Architecture	No domain graphic available
Description	Protein C21orf67.

KPCD3_MOUSE
θ value	6.88961 (rank : 30)	NC score	0.001718 (rank : 35)
Query Neighborhood Hits	33	Target Neighborhood Hits	901	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K1Y2	Gene names	Prkd3, Prkcn
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) (nPKC-nu).

OPTN_HUMAN
θ value	6.88961 (rank : 31)	NC score	0.008077 (rank : 32)
Query Neighborhood Hits	33	Target Neighborhood Hits	827	Shared Neighborhood Hits	4
SwissProt Accessions	Q96CV9, Q5T672, Q5T673, Q5T674, Q5T675, Q7LDL9, Q8N562, Q9UET9, Q9UEV4, Q9Y218	Gene names	OPTN, FIP2, GLC1E, NRP
Domain Architecture	No domain graphic available
Description	Optineurin (Optic neuropathy-inducing protein) (E3-14.7K-interacting protein) (FIP-2) (Huntingtin-interacting protein HYPL) (NEMO-related protein) (Transcription factor IIIA-interacting protein) (TFIIIA- IntP).

US6NL_MOUSE
θ value	6.88961 (rank : 32)	NC score	0.011337 (rank : 29)
Query Neighborhood Hits	33	Target Neighborhood Hits	157	Shared Neighborhood Hits	2
SwissProt Accessions	Q80XC3, Q6ZQK8	Gene names	Usp6nl, Kiaa0019
Domain Architecture	No domain graphic available
Description	USP6 N-terminal-like protein.

OFD1_HUMAN
θ value	8.99809 (rank : 33)	NC score	0.008139 (rank : 30)
Query Neighborhood Hits	33	Target Neighborhood Hits	753	Shared Neighborhood Hits	4
SwissProt Accessions	O75665, O75666	Gene names	OFD1, CXorf5
Domain Architecture	No domain graphic available
Description	Oral-facial-digital syndrome 1 protein (Protein 71-7A).

FIGN_HUMAN
θ value	θ > 10 (rank : 34)	NC score	0.051037 (rank : 7)
Query Neighborhood Hits	33	Target Neighborhood Hits	176	Shared Neighborhood Hits	6
SwissProt Accessions	Q5HY92, Q9H6M5, Q9NVZ9	Gene names	FIGN
Domain Architecture	No domain graphic available
Description	Fidgetin.

FIGN_MOUSE
θ value	θ > 10 (rank : 35)	NC score	0.050701 (rank : 8)
Query Neighborhood Hits	33	Target Neighborhood Hits	165	Shared Neighborhood Hits	6
SwissProt Accessions	Q9ERZ6, Q3TPB0, Q3UP57, Q6PCM0	Gene names	Fign
Domain Architecture	No domain graphic available
Description	Fidgetin.

Hits sorted by NC score

SPG20_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	33	Target Neighborhood Hits	33	Shared Neighborhood Hits	33
SwissProt Accessions	Q8R1X6, Q6ZQ87, Q8BJD3, Q8BM37, Q8BZ63	Gene names	Spg20, Kiaa0610
Domain Architecture	No domain graphic available
Description	Spartin.

SPG20_HUMAN
NC score	0.988929 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	33	Target Neighborhood Hits	28	Shared Neighborhood Hits	9
SwissProt Accessions	Q8N0X7, O60349, Q86Y67, Q9H1T2, Q9H1T3	Gene names	SPG20, KIAA0610, TAHCCP1
Domain Architecture	No domain graphic available
Description	Spartin (Trans-activated by hepatitis C virus core protein 1).

SPAST_MOUSE
NC score	0.152692 (rank : 3)	θ value	4.0297e-08 (rank : 3)
Query Neighborhood Hits	33	Target Neighborhood Hits	138	Shared Neighborhood Hits	5
SwissProt Accessions	Q9QYY8, Q6ZPY6, Q80VE0, Q9CVK0	Gene names	Spast, Kiaa1083, Spg4
Domain Architecture	No domain graphic available
Description	Spastin.

SPAST_HUMAN
NC score	0.144415 (rank : 4)	θ value	5.81887e-07 (rank : 4)
Query Neighborhood Hits	33	Target Neighborhood Hits	100	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UBP0, Q9UPR9	Gene names	SPAST, KIAA1083, SPG4
Domain Architecture
Description	Spastin.

MTSS1_HUMAN
NC score	0.066034 (rank : 5)	θ value	0.21417 (rank : 5)
Query Neighborhood Hits	33	Target Neighborhood Hits	504	Shared Neighborhood Hits	7
SwissProt Accessions	O43312, Q8TCA2, Q96RX2	Gene names	MTSS1, KIAA0429, MIM
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein) (Metastasis suppressor YGL-1).

MTSS1_MOUSE
NC score	0.057220 (rank : 6)	θ value	0.813845 (rank : 7)
Query Neighborhood Hits	33	Target Neighborhood Hits	592	Shared Neighborhood Hits	7
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

FIGN_HUMAN
NC score	0.051037 (rank : 7)	θ value	θ > 10 (rank : 34)
Query Neighborhood Hits	33	Target Neighborhood Hits	176	Shared Neighborhood Hits	6
SwissProt Accessions	Q5HY92, Q9H6M5, Q9NVZ9	Gene names	FIGN
Domain Architecture	No domain graphic available
Description	Fidgetin.

FIGN_MOUSE
NC score	0.050701 (rank : 8)	θ value	θ > 10 (rank : 35)
Query Neighborhood Hits	33	Target Neighborhood Hits	165	Shared Neighborhood Hits	6
SwissProt Accessions	Q9ERZ6, Q3TPB0, Q3UP57, Q6PCM0	Gene names	Fign
Domain Architecture	No domain graphic available
Description	Fidgetin.

SNP29_MOUSE
NC score	0.041248 (rank : 9)	θ value	1.38821 (rank : 12)
Query Neighborhood Hits	33	Target Neighborhood Hits	65	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ERB0, Q3UGN0, Q9DBC5	Gene names	Snap29
Domain Architecture
Description	Synaptosomal-associated protein 29 (SNAP-29) (Vesicle-membrane fusion protein SNAP-29) (Soluble 29 kDa NSF attachment protein) (Golgi SNARE of 32 kDa) (Gs32).

SEBP2_HUMAN
NC score	0.039551 (rank : 10)	θ value	1.38821 (rank : 11)
Query Neighborhood Hits	33	Target Neighborhood Hits	88	Shared Neighborhood Hits	3
SwissProt Accessions	Q96T21, Q8IYC0	Gene names	SECISBP2, SBP2
Domain Architecture
Description	SECIS-binding protein 2 (Selenocysteine insertion sequence-binding protein 2).

GRIN1_HUMAN
NC score	0.036380 (rank : 11)	θ value	0.365318 (rank : 6)
Query Neighborhood Hits	33	Target Neighborhood Hits	681	Shared Neighborhood Hits	4
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

OCLN_HUMAN
NC score	0.036279 (rank : 12)	θ value	3.0926 (rank : 19)
Query Neighborhood Hits	33	Target Neighborhood Hits	131	Shared Neighborhood Hits	4
SwissProt Accessions	Q16625, Q8N6K1	Gene names	OCLN
Domain Architecture
Description	Occludin.

CU067_HUMAN
NC score	0.030722 (rank : 13)	θ value	6.88961 (rank : 29)
Query Neighborhood Hits	33	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	P58512	Gene names	C21orf67
Domain Architecture	No domain graphic available
Description	Protein C21orf67.

JPH2_MOUSE
NC score	0.028661 (rank : 14)	θ value	3.0926 (rank : 18)
Query Neighborhood Hits	33	Target Neighborhood Hits	279	Shared Neighborhood Hits	7
SwissProt Accessions	Q9ET78, Q9ET79	Gene names	Jph2, Jp2
Domain Architecture	No domain graphic available
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

NACAM_MOUSE
NC score	0.027796 (rank : 15)	θ value	1.81305 (rank : 13)
Query Neighborhood Hits	33	Target Neighborhood Hits	1866	Shared Neighborhood Hits	11
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

PSIP1_MOUSE
NC score	0.026796 (rank : 16)	θ value	4.03905 (rank : 25)
Query Neighborhood Hits	33	Target Neighborhood Hits	313	Shared Neighborhood Hits	4
SwissProt Accessions	Q99JF8, Q3TEJ7, Q3TTD7, Q3UTA1, Q80WQ7, Q99JF7, Q99LR4, Q9CT03	Gene names	Psip1, Ledgf
Domain Architecture	No domain graphic available
Description	PC4 and SFRS1-interacting protein (Lens epithelium-derived growth factor) (mLEDGF).

PSIP1_HUMAN
NC score	0.025982 (rank : 17)	θ value	4.03905 (rank : 24)
Query Neighborhood Hits	33	Target Neighborhood Hits	341	Shared Neighborhood Hits	3
SwissProt Accessions	O75475, O00256, O95368, Q6P391, Q86YB9, Q9NZI3, Q9UER6	Gene names	PSIP1, DFS70, LEDGF, PSIP2
Domain Architecture	No domain graphic available
Description	PC4 and SFRS1-interacting protein (Lens epithelium-derived growth factor) (Transcriptional coactivator p75/p52) (Dense fine speckles 70 kDa protein) (DFS 70) (CLL-associated antigen KW-7).

EDN3_HUMAN
NC score	0.024595 (rank : 18)	θ value	5.27518 (rank : 26)
Query Neighborhood Hits	33	Target Neighborhood Hits	61	Shared Neighborhood Hits	3
SwissProt Accessions	P14138, Q03229	Gene names	EDN3
Domain Architecture
Description	Endothelin-3 precursor (ET-3) (Preproendothelin-3) (PPET3).

RECQ4_MOUSE
NC score	0.023790 (rank : 19)	θ value	1.38821 (rank : 9)
Query Neighborhood Hits	33	Target Neighborhood Hits	206	Shared Neighborhood Hits	3
SwissProt Accessions	Q75NR7, Q76MT1, Q99PV9	Gene names	Recql4, Recq4
Domain Architecture	No domain graphic available
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4).

OGFR_HUMAN
NC score	0.023388 (rank : 20)	θ value	1.06291 (rank : 8)
Query Neighborhood Hits	33	Target Neighborhood Hits	1582	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

DOK2_MOUSE
NC score	0.021129 (rank : 21)	θ value	4.03905 (rank : 22)
Query Neighborhood Hits	33	Target Neighborhood Hits	244	Shared Neighborhood Hits	6
SwissProt Accessions	O70469, O70272, Q99KL1	Gene names	Dok2, Frip
Domain Architecture
Description	Docking protein 2 (Downstream of tyrosine kinase 2) (p56(dok-2)) (Dok- related protein) (Dok-R) (IL-four receptor-interacting protein) (FRIP).

PDZD2_HUMAN
NC score	0.017266 (rank : 22)	θ value	3.0926 (rank : 20)
Query Neighborhood Hits	33	Target Neighborhood Hits	772	Shared Neighborhood Hits	5
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

RPTN_MOUSE
NC score	0.016550 (rank : 23)	θ value	1.38821 (rank : 10)
Query Neighborhood Hits	33	Target Neighborhood Hits	650	Shared Neighborhood Hits	4
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

MUC1_HUMAN
NC score	0.014971 (rank : 24)	θ value	2.36792 (rank : 17)
Query Neighborhood Hits	33	Target Neighborhood Hits	975	Shared Neighborhood Hits	6
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

TRBM_HUMAN
NC score	0.013529 (rank : 25)	θ value	1.81305 (rank : 15)
Query Neighborhood Hits	33	Target Neighborhood Hits	339	Shared Neighborhood Hits	3
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

GCC2_MOUSE
NC score	0.012171 (rank : 26)	θ value	2.36792 (rank : 16)
Query Neighborhood Hits	33	Target Neighborhood Hits	1619	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

PDZD1_MOUSE
NC score	0.011896 (rank : 27)	θ value	5.27518 (rank : 27)
Query Neighborhood Hits	33	Target Neighborhood Hits	191	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JIL4, Q8CDP5, Q8R4G2, Q9CQ72	Gene names	Pdzk1, Cap70, Nherf3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

PITM1_MOUSE
NC score	0.011604 (rank : 28)	θ value	5.27518 (rank : 28)
Query Neighborhood Hits	33	Target Neighborhood Hits	69	Shared Neighborhood Hits	2
SwissProt Accessions	O35954	Gene names	Pitpnm1, Dres9, Mpt1, Nir2, Pitpnm
Domain Architecture	No domain graphic available
Description	Membrane-associated phosphatidylinositol transfer protein 1 (Phosphatidylinositol transfer protein, membrane-associated 1) (PITPnm 1) (Mpt-1) (Pyk2 N-terminal domain-interacting receptor 2) (NIR-2) (Drosophila retinal degeneration B homolog 1) (RdgB1).

US6NL_MOUSE
NC score	0.011337 (rank : 29)	θ value	6.88961 (rank : 32)
Query Neighborhood Hits	33	Target Neighborhood Hits	157	Shared Neighborhood Hits	2
SwissProt Accessions	Q80XC3, Q6ZQK8	Gene names	Usp6nl, Kiaa0019
Domain Architecture	No domain graphic available
Description	USP6 N-terminal-like protein.

OFD1_HUMAN
NC score	0.008139 (rank : 30)	θ value	8.99809 (rank : 33)
Query Neighborhood Hits	33	Target Neighborhood Hits	753	Shared Neighborhood Hits	4
SwissProt Accessions	O75665, O75666	Gene names	OFD1, CXorf5
Domain Architecture	No domain graphic available
Description	Oral-facial-digital syndrome 1 protein (Protein 71-7A).

NELL2_MOUSE
NC score	0.008128 (rank : 31)	θ value	4.03905 (rank : 23)
Query Neighborhood Hits	33	Target Neighborhood Hits	436	Shared Neighborhood Hits	3
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

OPTN_HUMAN
NC score	0.008077 (rank : 32)	θ value	6.88961 (rank : 31)
Query Neighborhood Hits	33	Target Neighborhood Hits	827	Shared Neighborhood Hits	4
SwissProt Accessions	Q96CV9, Q5T672, Q5T673, Q5T674, Q5T675, Q7LDL9, Q8N562, Q9UET9, Q9UEV4, Q9Y218	Gene names	OPTN, FIP2, GLC1E, NRP
Domain Architecture	No domain graphic available
Description	Optineurin (Optic neuropathy-inducing protein) (E3-14.7K-interacting protein) (FIP-2) (Huntingtin-interacting protein HYPL) (NEMO-related protein) (Transcription factor IIIA-interacting protein) (TFIIIA- IntP).

CP4F3_MOUSE
NC score	0.007365 (rank : 33)	θ value	4.03905 (rank : 21)
Query Neighborhood Hits	33	Target Neighborhood Hits	111	Shared Neighborhood Hits	2
SwissProt Accessions	Q99N16, Q9D8N4	Gene names	Cyp4f3, Cyp4f18
Domain Architecture	No domain graphic available
Description	Cytochrome P450 4F3 (EC 1.14.13.30) (CYPIVF3) (Leukotriene-B(4) omega- hydroxylase) (Leukotriene-B(4) 20-monooxygenase) (Cytochrome P450-LTB- omega).

PASK_HUMAN
NC score	0.005563 (rank : 34)	θ value	1.81305 (rank : 14)
Query Neighborhood Hits	33	Target Neighborhood Hits	857	Shared Neighborhood Hits	3
SwissProt Accessions	Q96RG2, Q86XH6, Q99763, Q9UFR7	Gene names	PASK, KIAA0135
Domain Architecture
Description	PAS domain-containing serine/threonine-protein kinase (EC 2.7.11.1) (PAS-kinase) (PASKIN) (hPASK).

KPCD3_MOUSE
NC score	0.001718 (rank : 35)	θ value	6.88961 (rank : 30)
Query Neighborhood Hits	33	Target Neighborhood Hits	901	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K1Y2	Gene names	Prkd3, Prkcn
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) (nPKC-nu).