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Network neighborhood for query Sequence : NALP7_HUMAN

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NALP7_HUMAN
SwissProt Accessions	Q8WX94, Q7RTR1	Gene names	NALP7, NOD12, PYPAF3
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 7 (PYRIN-containing APAF1-like protein 3).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

NALP2_HUMAN
θ value	0 (rank : 1)	NC score	0.990483 (rank : 2)
Query Neighborhood Hits	65	Target Neighborhood Hits	65	Shared Neighborhood Hits	42
SwissProt Accessions	Q9NX02, Q53FL5, Q59G09, Q8IXT0, Q9BVN5, Q9H6G6, Q9HAV9, Q9NWK3	Gene names	NALP2, NBS1, PAN1, PYPAF2
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 2 (PYRIN domain and NACHT domain-containing protein 1) (PYRIN-containing APAF1-like protein 2) (Nucleotide-binding site protein 1).

NALP7_HUMAN
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	65	Target Neighborhood Hits	65	Shared Neighborhood Hits	65
SwissProt Accessions	Q8WX94, Q7RTR1	Gene names	NALP7, NOD12, PYPAF3
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 7 (PYRIN-containing APAF1-like protein 3).

NAL14_HUMAN
θ value	1.42253e-146 (rank : 3)	NC score	0.970727 (rank : 3)
Query Neighborhood Hits	65	Target Neighborhood Hits	76	Shared Neighborhood Hits	38
SwissProt Accessions	Q86W24, Q7RTR6	Gene names	NALP14, NOD5
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 14 (Nucleotide-binding oligomerization domain protein 5).

NAL13_HUMAN
θ value	8.69046e-120 (rank : 4)	NC score	0.966937 (rank : 5)
Query Neighborhood Hits	65	Target Neighborhood Hits	93	Shared Neighborhood Hits	36
SwissProt Accessions	Q86W25, Q7RTR5	Gene names	NALP13, NOD14
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 13 (Nucleotide-binding oligomerization domain protein 14).

NALP4_HUMAN
θ value	1.48236e-119 (rank : 5)	NC score	0.970014 (rank : 4)
Query Neighborhood Hits	65	Target Neighborhood Hits	81	Shared Neighborhood Hits	42
SwissProt Accessions	Q96MN2, Q86W87, Q96AY6	Gene names	NALP4, PAN2, PYPAF4, RNH2
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 4 (PYRIN-containing APAF1-like protein 4) (PAAD and NACHT-containing protein 2) (PYRIN and NACHT- containing protein 2) (Ribonuclease inhibitor 2).

CIAS1_MOUSE
θ value	2.6227e-108 (rank : 6)	NC score	0.959536 (rank : 8)
Query Neighborhood Hits	65	Target Neighborhood Hits	67	Shared Neighborhood Hits	40
SwissProt Accessions	Q8R4B8, Q6JEL0	Gene names	Cias1, Mmig1, Nalp3, Pypaf1
Domain Architecture
Description	Cold autoinflammatory syndrome 1 protein homolog (PYRIN-containing APAF1-like protein 1) (Mast cell maturation-associated-inducible protein 1) (Cryopyrin).

NAL12_HUMAN
θ value	3.42535e-108 (rank : 7)	NC score	0.960325 (rank : 6)
Query Neighborhood Hits	65	Target Neighborhood Hits	96	Shared Neighborhood Hits	43
SwissProt Accessions	P59046, Q8NEU4, Q9BY26	Gene names	NALP12, PYPAF7, RNO
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 12 (PYRIN-containing APAF1-like protein 7) (Monarch-1) (Regulated by nitric oxide).

CIAS1_HUMAN
θ value	2.89973e-107 (rank : 8)	NC score	0.960195 (rank : 7)
Query Neighborhood Hits	65	Target Neighborhood Hits	76	Shared Neighborhood Hits	40
SwissProt Accessions	Q96P20, O75434, Q59H68, Q5JQS8, Q5JQS9, Q6TG35, Q8TCW0, Q8TEU9, Q8WXH9	Gene names	CIAS1, NALP3, PYPAF1
Domain Architecture
Description	Cold autoinflammatory syndrome 1 protein (Cryopyrin) (NACHT-, LRR- and PYD-containing protein 3) (PYRIN-containing APAF1-like protein 1) (Angiotensin/vasopressin receptor AII/AVP-like).

NALP5_MOUSE
θ value	2.45477e-106 (rank : 9)	NC score	0.888263 (rank : 16)
Query Neighborhood Hits	65	Target Neighborhood Hits	560	Shared Neighborhood Hits	43
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

NALP5_HUMAN
θ value	2.37764e-101 (rank : 10)	NC score	0.950418 (rank : 9)
Query Neighborhood Hits	65	Target Neighborhood Hits	88	Shared Neighborhood Hits	39
SwissProt Accessions	P59047, Q86W29	Gene names	NALP5, MATER
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Mater protein homolog).

NAL11_HUMAN
θ value	5.15425e-80 (rank : 11)	NC score	0.944051 (rank : 10)
Query Neighborhood Hits	65	Target Neighborhood Hits	66	Shared Neighborhood Hits	30
SwissProt Accessions	P59045, Q53ZZ0, Q8NBF5	Gene names	NALP11, NOD17, PYPAF6
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 11 (PYRIN-containing APAF1-like protein 6) (Nucleotide-binding oligomerization domain protein 17).

NALP1_HUMAN
θ value	3.34088e-79 (rank : 12)	NC score	0.915250 (rank : 13)
Query Neighborhood Hits	65	Target Neighborhood Hits	138	Shared Neighborhood Hits	39
SwissProt Accessions	Q9C000, Q9BZZ8, Q9BZZ9, Q9HAV8, Q9UFT4, Q9Y2E0	Gene names	NALP1, CARD7, DEFCAP, KIAA0926, NAC
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 1 (Death effector filament- forming ced-4-like apoptosis protein) (Nucleotide-binding domain and caspase recruitment domain) (Caspase recruitment domain protein 7).

NALP6_MOUSE
θ value	1.84173e-61 (rank : 13)	NC score	0.934865 (rank : 11)
Query Neighborhood Hits	65	Target Neighborhood Hits	55	Shared Neighborhood Hits	38
SwissProt Accessions	Q91WS2, Q8K0L4	Gene names	Nalp6, Pypaf5
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 6 (PYRIN-containing APAF1-like protein 5-like).

NALP6_HUMAN
θ value	1.19377e-60 (rank : 14)	NC score	0.933698 (rank : 12)
Query Neighborhood Hits	65	Target Neighborhood Hits	52	Shared Neighborhood Hits	37
SwissProt Accessions	P59044	Gene names	NALP6, PYPAF5
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 6 (PYRIN-containing APAF1-like protein 5).

NAL10_HUMAN
θ value	6.34462e-54 (rank : 15)	NC score	0.903836 (rank : 14)
Query Neighborhood Hits	65	Target Neighborhood Hits	55	Shared Neighborhood Hits	33
SwissProt Accessions	Q86W26, Q6JGT0	Gene names	NALP10, NOD8, PYNOD
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 10 (Nucleotide-binding oligomerization domain protein 8).

NAL10_MOUSE
θ value	1.61718e-49 (rank : 16)	NC score	0.901681 (rank : 15)
Query Neighborhood Hits	65	Target Neighborhood Hits	46	Shared Neighborhood Hits	34
SwissProt Accessions	Q8CCN1	Gene names	Nalp10, Pynod
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 10.

RINI_MOUSE
θ value	1.24399e-33 (rank : 17)	NC score	0.844254 (rank : 17)
Query Neighborhood Hits	65	Target Neighborhood Hits	87	Shared Neighborhood Hits	28
SwissProt Accessions	Q91VI7, Q924P4	Gene names	Rnh1, Rnh
Domain Architecture	No domain graphic available
Description	Ribonuclease inhibitor (Ribonuclease/angiogenin inhibitor 1).

RINI_HUMAN
θ value	1.92365e-26 (rank : 18)	NC score	0.843461 (rank : 18)
Query Neighborhood Hits	65	Target Neighborhood Hits	78	Shared Neighborhood Hits	28
SwissProt Accessions	P13489	Gene names	RNH1, PRI, RNH
Domain Architecture
Description	Ribonuclease inhibitor (Ribonuclease/angiogenin inhibitor 1) (RAI) (Placental ribonuclease inhibitor) (RNase inhibitor) (RI).

CAR15_MOUSE
θ value	1.05554e-24 (rank : 19)	NC score	0.745346 (rank : 19)
Query Neighborhood Hits	65	Target Neighborhood Hits	93	Shared Neighborhood Hits	37
SwissProt Accessions	Q8K3Z0	Gene names	Card15, Nod2
Domain Architecture
Description	Caspase recruitment domain-containing protein 15 (Protein Nod2).

CARD4_HUMAN
θ value	1.29031e-22 (rank : 20)	NC score	0.699467 (rank : 22)
Query Neighborhood Hits	65	Target Neighborhood Hits	102	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Y239, Q8IWF5	Gene names	CARD4, NOD1
Domain Architecture
Description	Caspase recruitment domain-containing protein 4 (Protein Nod1).

CARD4_MOUSE
θ value	2.20094e-22 (rank : 21)	NC score	0.708218 (rank : 21)
Query Neighborhood Hits	65	Target Neighborhood Hits	85	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BHB0, Q8BUT6	Gene names	Card4
Domain Architecture
Description	Caspase recruitment domain-containing protein 4.

C2TA_HUMAN
θ value	1.058e-16 (rank : 22)	NC score	0.628721 (rank : 24)
Query Neighborhood Hits	65	Target Neighborhood Hits	190	Shared Neighborhood Hits	30
SwissProt Accessions	P33076	Gene names	CIITA, MHC2TA
Domain Architecture
Description	MHC class II transactivator (CIITA).

CAR15_HUMAN
θ value	1.68911e-14 (rank : 23)	NC score	0.720065 (rank : 20)
Query Neighborhood Hits	65	Target Neighborhood Hits	77	Shared Neighborhood Hits	37
SwissProt Accessions	Q9HC29, Q96RH5, Q96RH6, Q96RH8	Gene names	CARD15, IBD1, NOD2
Domain Architecture
Description	Caspase recruitment domain-containing protein 15 (Protein Nod2) (Inflammatory bowel disease protein 1).

C2TA_MOUSE
θ value	3.76295e-14 (rank : 24)	NC score	0.644568 (rank : 23)
Query Neighborhood Hits	65	Target Neighborhood Hits	131	Shared Neighborhood Hits	36
SwissProt Accessions	P79621, O46787, O78036, O78109, Q31115, Q9TPP1	Gene names	Ciita, C2ta, Mhc2ta
Domain Architecture
Description	MHC class II transactivator (CIITA).

LRC34_HUMAN
θ value	3.89403e-11 (rank : 25)	NC score	0.547993 (rank : 25)
Query Neighborhood Hits	65	Target Neighborhood Hits	67	Shared Neighborhood Hits	27
SwissProt Accessions	Q8IZ02	Gene names	LRRC34
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 34.

BIRC1_HUMAN
θ value	1.29631e-06 (rank : 26)	NC score	0.279722 (rank : 33)
Query Neighborhood Hits	65	Target Neighborhood Hits	61	Shared Neighborhood Hits	31
SwissProt Accessions	Q13075, O75857, Q13730, Q99796	Gene names	BIRC1, NAIP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1 (Neuronal apoptosis inhibitory protein).

BIR1E_MOUSE
θ value	1.69304e-06 (rank : 27)	NC score	0.254121 (rank : 36)
Query Neighborhood Hits	65	Target Neighborhood Hits	93	Shared Neighborhood Hits	27
SwissProt Accessions	Q9R016, O09121, O09122, P81703, Q9R029	Gene names	Birc1e, Naip-rs3, Naip5
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1e (Neuronal apoptosis inhibitory protein 5).

BIR1F_MOUSE
θ value	2.88788e-06 (rank : 28)	NC score	0.255954 (rank : 35)
Query Neighborhood Hits	65	Target Neighborhood Hits	88	Shared Neighborhood Hits	28
SwissProt Accessions	Q9JIB6, O09121, O09122, P81704	Gene names	Birc1f, Naip-rs4, Naip6
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1f (Neuronal apoptosis inhibitory protein 6).

BIR1G_MOUSE
θ value	2.88788e-06 (rank : 29)	NC score	0.248712 (rank : 37)
Query Neighborhood Hits	65	Target Neighborhood Hits	92	Shared Neighborhood Hits	27
SwissProt Accessions	Q9JIB3	Gene names	Birc1g, Naip7
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1g (Neuronal apoptosis inhibitory protein 7).

LRC34_MOUSE
θ value	2.44474e-05 (rank : 30)	NC score	0.505973 (rank : 26)
Query Neighborhood Hits	65	Target Neighborhood Hits	58	Shared Neighborhood Hits	26
SwissProt Accessions	Q9DAM1	Gene names	Lrrc34
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 34.

BIR1A_MOUSE
θ value	4.1701e-05 (rank : 31)	NC score	0.259416 (rank : 34)
Query Neighborhood Hits	65	Target Neighborhood Hits	94	Shared Neighborhood Hits	27
SwissProt Accessions	Q9QWK5, Q9JIB5, Q9R017	Gene names	Birc1a, Naip, Naip1
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1a (Neuronal apoptosis inhibitory protein 1).

BIR1B_MOUSE
θ value	0.000461057 (rank : 32)	NC score	0.239949 (rank : 38)
Query Neighborhood Hits	65	Target Neighborhood Hits	93	Shared Neighborhood Hits	29
SwissProt Accessions	Q9QUK4, O09124, Q9R030	Gene names	Birc1b, Naip-rs6, Naip2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1b (Neuronal apoptosis inhibitory protein 2).

LRC31_HUMAN
θ value	0.00102713 (rank : 33)	NC score	0.486732 (rank : 27)
Query Neighborhood Hits	65	Target Neighborhood Hits	139	Shared Neighborhood Hits	32
SwissProt Accessions	Q6UY01, Q8N848, Q9H5N5	Gene names	LRRC31
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 31.

ASC_MOUSE
θ value	0.00665767 (rank : 34)	NC score	0.292250 (rank : 31)
Query Neighborhood Hits	65	Target Neighborhood Hits	17	Shared Neighborhood Hits	15
SwissProt Accessions	Q9EPB4, Q9D2W9	Gene names	Pycard, Asc
Domain Architecture
Description	Apoptosis-associated speck-like protein containing a CARD (mASC) (PYD and CARD domain-containing protein).

CAR12_HUMAN
θ value	0.0193708 (rank : 35)	NC score	0.355264 (rank : 29)
Query Neighborhood Hits	65	Target Neighborhood Hits	132	Shared Neighborhood Hits	34
SwissProt Accessions	Q9NPP4, Q96J81, Q96J82, Q96J83	Gene names	CARD12, CLAN, CLAN1
Domain Architecture
Description	Caspase recruitment domain-containing protein 12 (Ice protease- activating factor) (Ipaf) (CARD, LRR, and NACHT-containing protein) (Clan protein).

CP250_MOUSE
θ value	0.365318 (rank : 36)	NC score	0.005364 (rank : 76)
Query Neighborhood Hits	65	Target Neighborhood Hits	1583	Shared Neighborhood Hits	7
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

NVL_MOUSE
θ value	0.365318 (rank : 37)	NC score	0.020852 (rank : 63)
Query Neighborhood Hits	65	Target Neighborhood Hits	110	Shared Neighborhood Hits	15
SwissProt Accessions	Q9DBY8, Q3USC4, Q8BW27, Q8K2B5	Gene names	Nvl
Domain Architecture
Description	Nuclear valosin-containing protein-like (Nuclear VCP-like protein) (NVLp).

PEO1_HUMAN
θ value	0.62314 (rank : 38)	NC score	0.029406 (rank : 57)
Query Neighborhood Hits	65	Target Neighborhood Hits	18	Shared Neighborhood Hits	5
SwissProt Accessions	Q96RR1, Q6MZX2, Q96RR0	Gene names	PEO1, C10orf2
Domain Architecture	No domain graphic available
Description	Twinkle protein, mitochondrial precursor (EC 3.6.1.-) (T7 gp4-like protein with intramitochondrial nucleoid localization) (T7-like mitochondrial DNA helicase) (Progressive external ophthalmoplegia 1 protein).

CF154_HUMAN
θ value	0.813845 (rank : 39)	NC score	0.469071 (rank : 28)
Query Neighborhood Hits	65	Target Neighborhood Hits	36	Shared Neighborhood Hits	25
SwissProt Accessions	Q5JTD7	Gene names	C6orf154
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf154.

MEFV_HUMAN
θ value	1.06291 (rank : 40)	NC score	0.081250 (rank : 45)
Query Neighborhood Hits	65	Target Neighborhood Hits	431	Shared Neighborhood Hits	16
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

LRC45_MOUSE
θ value	1.38821 (rank : 41)	NC score	0.160165 (rank : 40)
Query Neighborhood Hits	65	Target Neighborhood Hits	959	Shared Neighborhood Hits	30
SwissProt Accessions	Q8CIM1, Q3U5Z2	Gene names	Lrrc45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

PEX6_HUMAN
θ value	1.38821 (rank : 42)	NC score	0.020078 (rank : 64)
Query Neighborhood Hits	65	Target Neighborhood Hits	99	Shared Neighborhood Hits	14
SwissProt Accessions	Q13608, Q8WYQ2, Q99476	Gene names	PEX6, PXAAA1
Domain Architecture
Description	Peroxisome assembly factor 2 (PAF-2) (Peroxisomal-type ATPase 1) (Peroxin-6) (Peroxisomal biogenesis factor 6).

PEX6_MOUSE
θ value	1.38821 (rank : 43)	NC score	0.020059 (rank : 65)
Query Neighborhood Hits	65	Target Neighborhood Hits	94	Shared Neighborhood Hits	14
SwissProt Accessions	Q99LC9, Q6YNQ9	Gene names	Pex6
Domain Architecture	No domain graphic available
Description	Peroxisome assembly factor 2 (PAF-2) (Peroxisomal-type ATPase 1) (Peroxin-6) (Peroxisomal biogenesis factor 6).

CP250_HUMAN
θ value	2.36792 (rank : 44)	NC score	0.001893 (rank : 77)
Query Neighborhood Hits	65	Target Neighborhood Hits	1805	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

ZNF35_HUMAN
θ value	2.36792 (rank : 45)	NC score	-0.003495 (rank : 80)
Query Neighborhood Hits	65	Target Neighborhood Hits	761	Shared Neighborhood Hits	3
SwissProt Accessions	P13682, Q96D01	Gene names	ZNF35
Domain Architecture	No domain graphic available
Description	Zinc finger protein 35 (Zinc finger protein HF.10).

ASC_HUMAN
θ value	3.0926 (rank : 46)	NC score	0.224778 (rank : 39)
Query Neighborhood Hits	65	Target Neighborhood Hits	18	Shared Neighborhood Hits	14
SwissProt Accessions	Q9ULZ3, Q96D12, Q9BSZ5, Q9HBD0, Q9NXJ8	Gene names	PYCARD, ASC, CARD5, TMS1
Domain Architecture
Description	Apoptosis-associated speck-like protein containing a CARD (hASC) (PYD and CARD domain-containing protein) (Target of methylation-induced silencing 1) (Caspase recruitment domain-containing protein 5).

PEO1_MOUSE
θ value	3.0926 (rank : 47)	NC score	0.026117 (rank : 58)
Query Neighborhood Hits	65	Target Neighborhood Hits	27	Shared Neighborhood Hits	6
SwissProt Accessions	Q8CIW5, Q8K1Z1	Gene names	Peo1
Domain Architecture	No domain graphic available
Description	Twinkle protein, mitochondrial precursor (EC 3.6.1.-) (T7 gp4-like protein with intramitochondrial nucleoid localization) (T7-like mitochondrial DNA helicase) (Progressive external ophthalmoplegia 1 protein homolog).

PNPO_MOUSE
θ value	3.0926 (rank : 48)	NC score	0.015712 (rank : 68)
Query Neighborhood Hits	65	Target Neighborhood Hits	4	Shared Neighborhood Hits	2
SwissProt Accessions	Q91XF0	Gene names	Pnpo
Domain Architecture
Description	Pyridoxine-5'-phosphate oxidase (EC 1.4.3.5) (Pyridoxamine-phosphate oxidase).

TRP13_MOUSE
θ value	3.0926 (rank : 49)	NC score	0.025003 (rank : 59)
Query Neighborhood Hits	65	Target Neighborhood Hits	81	Shared Neighborhood Hits	12
SwissProt Accessions	Q3UA06, Q3UQG6, Q9CWW8	Gene names	Trip13
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 13 (Thyroid hormone receptor interactor 13) (Trip-13).

BMS1_HUMAN
θ value	5.27518 (rank : 50)	NC score	0.021475 (rank : 62)
Query Neighborhood Hits	65	Target Neighborhood Hits	109	Shared Neighborhood Hits	3
SwissProt Accessions	Q14692, Q86XJ9	Gene names	BMS1L, KIAA0187
Domain Architecture
Description	Ribosome biogenesis protein BMS1 homolog.

CLPX_HUMAN
θ value	5.27518 (rank : 51)	NC score	0.029716 (rank : 56)
Query Neighborhood Hits	65	Target Neighborhood Hits	72	Shared Neighborhood Hits	12
SwissProt Accessions	O76031, Q9H4D9	Gene names	CLPX
Domain Architecture
Description	ATP-dependent Clp protease ATP-binding subunit ClpX-like, mitochondrial precursor.

DHX57_HUMAN
θ value	5.27518 (rank : 52)	NC score	0.006527 (rank : 74)
Query Neighborhood Hits	65	Target Neighborhood Hits	109	Shared Neighborhood Hits	5
SwissProt Accessions	Q6P158, Q53SI4, Q6P9G1, Q7Z6H3, Q8NG17, Q96M33	Gene names	DHX57
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX57 (EC 3.6.1.-) (DEAH box protein 57).

DHX57_MOUSE
θ value	5.27518 (rank : 53)	NC score	0.006496 (rank : 75)
Query Neighborhood Hits	65	Target Neighborhood Hits	125	Shared Neighborhood Hits	5
SwissProt Accessions	Q6P5D3, Q3TS93, Q6NZK4, Q6P1B4, Q8BI63, Q8BIA2, Q8R360	Gene names	Dhx57
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX57 (EC 3.6.1.-) (DEAH box protein 57).

LRIG3_MOUSE
θ value	5.27518 (rank : 54)	NC score	-0.000680 (rank : 79)
Query Neighborhood Hits	65	Target Neighborhood Hits	611	Shared Neighborhood Hits	5
SwissProt Accessions	Q6P1C6, Q6ZPE6, Q8BRF0, Q8BS51, Q8C5E4	Gene names	Lrig3, Kiaa3016
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 3 precursor.

MEFV_MOUSE
θ value	5.27518 (rank : 55)	NC score	0.141454 (rank : 42)
Query Neighborhood Hits	65	Target Neighborhood Hits	236	Shared Neighborhood Hits	18
SwissProt Accessions	Q9JJ26	Gene names	Mefv
Domain Architecture
Description	Pyrin (Marenostrin).

TRP13_HUMAN
θ value	5.27518 (rank : 56)	NC score	0.023737 (rank : 60)
Query Neighborhood Hits	65	Target Neighborhood Hits	81	Shared Neighborhood Hits	13
SwissProt Accessions	Q15645, O15324	Gene names	TRIP13
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 13 (Thyroid hormone receptor interactor 13) (Trip-13) (Human papillomavirus type 16 E1 protein- binding protein) (HPV16 E1 protein-binding protein) (16E1-BP).

VPS4B_MOUSE
θ value	5.27518 (rank : 57)	NC score	0.011314 (rank : 69)
Query Neighborhood Hits	65	Target Neighborhood Hits	86	Shared Neighborhood Hits	12
SwissProt Accessions	P46467, Q91W22, Q9R1C9	Gene names	Vps4b, Skd1
Domain Architecture
Description	Vacuolar protein sorting-associating protein 4B (Protein SKD1).

CENPB_MOUSE
θ value	8.99809 (rank : 58)	NC score	0.015981 (rank : 67)
Query Neighborhood Hits	65	Target Neighborhood Hits	163	Shared Neighborhood Hits	4
SwissProt Accessions	P27790	Gene names	Cenpb, Cenp-b
Domain Architecture
Description	Major centromere autoantigen B (Centromere protein B) (CENP-B).

CK5P2_HUMAN
θ value	8.99809 (rank : 59)	NC score	0.001339 (rank : 78)
Query Neighborhood Hits	65	Target Neighborhood Hits	1433	Shared Neighborhood Hits	7
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

CLPX_MOUSE
θ value	8.99809 (rank : 60)	NC score	0.022344 (rank : 61)
Query Neighborhood Hits	65	Target Neighborhood Hits	73	Shared Neighborhood Hits	11
SwissProt Accessions	Q9JHS4, Q9WVD1	Gene names	Clpx
Domain Architecture
Description	ATP-dependent Clp protease ATP-binding subunit ClpX-like, mitochondrial precursor.

DIRA3_HUMAN
θ value	8.99809 (rank : 61)	NC score	0.007173 (rank : 73)
Query Neighborhood Hits	65	Target Neighborhood Hits	241	Shared Neighborhood Hits	7
SwissProt Accessions	O95661	Gene names	DIRAS3, ARHI, NOEY2, RHOI
Domain Architecture
Description	GTP-binding protein Di-Ras3 (Distinct subgroup of the Ras family member 3) (Rho-related GTP-binding protein RhoI).

KGUA_MOUSE
θ value	8.99809 (rank : 62)	NC score	0.010065 (rank : 72)
Query Neighborhood Hits	65	Target Neighborhood Hits	45	Shared Neighborhood Hits	4
SwissProt Accessions	Q64520	Gene names	Guk1, Gmk
Domain Architecture
Description	Guanylate kinase (EC 2.7.4.8) (GMP kinase).

NVL_HUMAN
θ value	8.99809 (rank : 63)	NC score	0.016579 (rank : 66)
Query Neighborhood Hits	65	Target Neighborhood Hits	112	Shared Neighborhood Hits	14
SwissProt Accessions	O15381, Q96EM7	Gene names	NVL
Domain Architecture
Description	Nuclear valosin-containing protein-like (Nuclear VCP-like protein) (NVLp).

PRS10_HUMAN
θ value	8.99809 (rank : 64)	NC score	0.010805 (rank : 70)
Query Neighborhood Hits	65	Target Neighborhood Hits	95	Shared Neighborhood Hits	12
SwissProt Accessions	P62333, P49719, Q6IBU3, Q92524	Gene names	PSMC6, SUG2
Domain Architecture
Description	26S protease regulatory subunit S10B (Proteasome subunit p42) (Proteasome 26S subunit ATPase 6).

PRS10_MOUSE
θ value	8.99809 (rank : 65)	NC score	0.010805 (rank : 71)
Query Neighborhood Hits	65	Target Neighborhood Hits	95	Shared Neighborhood Hits	12
SwissProt Accessions	P62334, P49719, Q3TKK1, Q810A6, Q92524, Q9CXH9	Gene names	Psmc6, Sug2
Domain Architecture
Description	26S protease regulatory subunit S10B (Proteasome subunit p42) (Proteasome 26S subunit ATPase 6).

BIRC2_HUMAN
θ value	θ > 10 (rank : 66)	NC score	0.057956 (rank : 47)
Query Neighborhood Hits	65	Target Neighborhood Hits	142	Shared Neighborhood Hits	9
SwissProt Accessions	Q13490, Q16516, Q4TTG0	Gene names	BIRC2, API1, IAP2, MIHB
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (HIAP2) (HIAP-2) (C-IAP1) (TNFR2-TRAF signaling complex protein 2) (IAP homolog B).

BIRC2_MOUSE
θ value	θ > 10 (rank : 67)	NC score	0.058920 (rank : 46)
Query Neighborhood Hits	65	Target Neighborhood Hits	137	Shared Neighborhood Hits	10
SwissProt Accessions	Q62210, O08864	Gene names	Birc2, Birc3, Iap2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (MIAP2) (MIAP-2).

BIRC3_HUMAN
θ value	θ > 10 (rank : 68)	NC score	0.052415 (rank : 52)
Query Neighborhood Hits	65	Target Neighborhood Hits	133	Shared Neighborhood Hits	7
SwissProt Accessions	Q13489, Q16628, Q9HC27, Q9UP46	Gene names	BIRC3, API2, IAP1, MIHC
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (HIAP1) (HIAP-1) (C-IAP2) (TNFR2-TRAF signaling complex protein 1) (IAP homolog C) (Apoptosis inhibitor 2) (API2).

BIRC3_MOUSE
θ value	θ > 10 (rank : 69)	NC score	0.052038 (rank : 53)
Query Neighborhood Hits	65	Target Neighborhood Hits	113	Shared Neighborhood Hits	6
SwissProt Accessions	O08863	Gene names	Birc3, Birc2, Iap1
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (MIAP1) (MIAP-1).

BIRC4_HUMAN
θ value	θ > 10 (rank : 70)	NC score	0.054412 (rank : 49)
Query Neighborhood Hits	65	Target Neighborhood Hits	89	Shared Neighborhood Hits	6
SwissProt Accessions	P98170, Q9NQ14	Gene names	BIRC4, API3, IAP3, XIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 4 (Inhibitor of apoptosis protein 3) (X-linked inhibitor of apoptosis protein) (X-linked IAP) (IAP-like protein) (HILP).

BIRC4_MOUSE
θ value	θ > 10 (rank : 71)	NC score	0.055585 (rank : 48)
Query Neighborhood Hits	65	Target Neighborhood Hits	89	Shared Neighborhood Hits	6
SwissProt Accessions	Q60989, O08865	Gene names	Birc4, Aipa, Api3, Miha, Xiap
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 4 (Inhibitor of apoptosis protein 3) (X-linked inhibitor of apoptosis protein) (X-linked IAP) (IAP homolog A) (MIAP3) (MIAP-3).

BIRC5_HUMAN
θ value	θ > 10 (rank : 72)	NC score	0.052462 (rank : 51)
Query Neighborhood Hits	65	Target Neighborhood Hits	20	Shared Neighborhood Hits	6
SwissProt Accessions	O15392, Q2I3N8, Q4VGX0, Q53F61, Q5MGC6, Q6FHL2, Q75SP2, Q9P2W8	Gene names	BIRC5, API4, IAP4
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 5 (Apoptosis inhibitor survivin) (Apoptosis inhibitor 4).

BIRC5_MOUSE
θ value	θ > 10 (rank : 73)	NC score	0.051538 (rank : 54)
Query Neighborhood Hits	65	Target Neighborhood Hits	19	Shared Neighborhood Hits	6
SwissProt Accessions	O70201, Q923F7, Q9WU53, Q9WU54	Gene names	Birc5, Api4, Iap4
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 5 (Apoptosis inhibitor survivin) (Apoptosis inhibitor 4) (TIAP).

CARD8_HUMAN
θ value	θ > 10 (rank : 74)	NC score	0.117084 (rank : 43)
Query Neighborhood Hits	65	Target Neighborhood Hits	22	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y2G2, Q6PGP8, Q96P82	Gene names	CARD8, KIAA0955, NDPP1
Domain Architecture
Description	Caspase recruitment domain-containing protein 8 (Apoptotic protein NDPP1) (DACAR) (CARD-inhibitor of NF-kappa-B-activating ligand) (CARDINAL) (Tumor-up-regulated CARD-containing antagonist of CASP9) (TUCAN).

CD14_MOUSE
θ value	θ > 10 (rank : 75)	NC score	0.050947 (rank : 55)
Query Neighborhood Hits	65	Target Neighborhood Hits	104	Shared Neighborhood Hits	7
SwissProt Accessions	P10810	Gene names	Cd14
Domain Architecture
Description	Monocyte differentiation antigen CD14 precursor (Myeloid cell-specific leucine-rich glycoprotein).

LRC14_HUMAN
θ value	θ > 10 (rank : 76)	NC score	0.082107 (rank : 44)
Query Neighborhood Hits	65	Target Neighborhood Hits	57	Shared Neighborhood Hits	16
SwissProt Accessions	Q15048	Gene names	LRRC14, KIAA0014
Domain Architecture
Description	Leucine-rich repeat-containing protein 14.

LRC45_HUMAN
θ value	θ > 10 (rank : 77)	NC score	0.148034 (rank : 41)
Query Neighborhood Hits	65	Target Neighborhood Hits	933	Shared Neighborhood Hits	29
SwissProt Accessions	Q96CN5	Gene names	LRRC45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

MAPE_HUMAN
θ value	θ > 10 (rank : 78)	NC score	0.052734 (rank : 50)
Query Neighborhood Hits	65	Target Neighborhood Hits	24	Shared Neighborhood Hits	9
SwissProt Accessions	P78395, O43481, Q8IXN8	Gene names	PRAME, MAPE
Domain Architecture	No domain graphic available
Description	Melanoma antigen preferentially expressed in tumors (Preferentially expressed antigen of melanoma) (OPA-interacting protein 4) (OIP4).

RGP1_HUMAN
θ value	θ > 10 (rank : 79)	NC score	0.301098 (rank : 30)
Query Neighborhood Hits	65	Target Neighborhood Hits	124	Shared Neighborhood Hits	23
SwissProt Accessions	P46060	Gene names	RANGAP1
Domain Architecture
Description	Ran GTPase-activating protein 1.

RGP1_MOUSE
θ value	θ > 10 (rank : 80)	NC score	0.286968 (rank : 32)
Query Neighborhood Hits	65	Target Neighborhood Hits	105	Shared Neighborhood Hits	23
SwissProt Accessions	P46061, Q60801	Gene names	Rangap1, Fug1
Domain Architecture
Description	Ran GTPase-activating protein 1.

Hits sorted by NC score

NALP7_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	65	Target Neighborhood Hits	65	Shared Neighborhood Hits	65
SwissProt Accessions	Q8WX94, Q7RTR1	Gene names	NALP7, NOD12, PYPAF3
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 7 (PYRIN-containing APAF1-like protein 3).

NALP2_HUMAN
NC score	0.990483 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	65	Target Neighborhood Hits	65	Shared Neighborhood Hits	42
SwissProt Accessions	Q9NX02, Q53FL5, Q59G09, Q8IXT0, Q9BVN5, Q9H6G6, Q9HAV9, Q9NWK3	Gene names	NALP2, NBS1, PAN1, PYPAF2
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 2 (PYRIN domain and NACHT domain-containing protein 1) (PYRIN-containing APAF1-like protein 2) (Nucleotide-binding site protein 1).

NAL14_HUMAN
NC score	0.970727 (rank : 3)	θ value	1.42253e-146 (rank : 3)
Query Neighborhood Hits	65	Target Neighborhood Hits	76	Shared Neighborhood Hits	38
SwissProt Accessions	Q86W24, Q7RTR6	Gene names	NALP14, NOD5
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 14 (Nucleotide-binding oligomerization domain protein 5).

NALP4_HUMAN
NC score	0.970014 (rank : 4)	θ value	1.48236e-119 (rank : 5)
Query Neighborhood Hits	65	Target Neighborhood Hits	81	Shared Neighborhood Hits	42
SwissProt Accessions	Q96MN2, Q86W87, Q96AY6	Gene names	NALP4, PAN2, PYPAF4, RNH2
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 4 (PYRIN-containing APAF1-like protein 4) (PAAD and NACHT-containing protein 2) (PYRIN and NACHT- containing protein 2) (Ribonuclease inhibitor 2).

NAL13_HUMAN
NC score	0.966937 (rank : 5)	θ value	8.69046e-120 (rank : 4)
Query Neighborhood Hits	65	Target Neighborhood Hits	93	Shared Neighborhood Hits	36
SwissProt Accessions	Q86W25, Q7RTR5	Gene names	NALP13, NOD14
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 13 (Nucleotide-binding oligomerization domain protein 14).

NAL12_HUMAN
NC score	0.960325 (rank : 6)	θ value	3.42535e-108 (rank : 7)
Query Neighborhood Hits	65	Target Neighborhood Hits	96	Shared Neighborhood Hits	43
SwissProt Accessions	P59046, Q8NEU4, Q9BY26	Gene names	NALP12, PYPAF7, RNO
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 12 (PYRIN-containing APAF1-like protein 7) (Monarch-1) (Regulated by nitric oxide).

CIAS1_HUMAN
NC score	0.960195 (rank : 7)	θ value	2.89973e-107 (rank : 8)
Query Neighborhood Hits	65	Target Neighborhood Hits	76	Shared Neighborhood Hits	40
SwissProt Accessions	Q96P20, O75434, Q59H68, Q5JQS8, Q5JQS9, Q6TG35, Q8TCW0, Q8TEU9, Q8WXH9	Gene names	CIAS1, NALP3, PYPAF1
Domain Architecture
Description	Cold autoinflammatory syndrome 1 protein (Cryopyrin) (NACHT-, LRR- and PYD-containing protein 3) (PYRIN-containing APAF1-like protein 1) (Angiotensin/vasopressin receptor AII/AVP-like).

CIAS1_MOUSE
NC score	0.959536 (rank : 8)	θ value	2.6227e-108 (rank : 6)
Query Neighborhood Hits	65	Target Neighborhood Hits	67	Shared Neighborhood Hits	40
SwissProt Accessions	Q8R4B8, Q6JEL0	Gene names	Cias1, Mmig1, Nalp3, Pypaf1
Domain Architecture
Description	Cold autoinflammatory syndrome 1 protein homolog (PYRIN-containing APAF1-like protein 1) (Mast cell maturation-associated-inducible protein 1) (Cryopyrin).

NALP5_HUMAN
NC score	0.950418 (rank : 9)	θ value	2.37764e-101 (rank : 10)
Query Neighborhood Hits	65	Target Neighborhood Hits	88	Shared Neighborhood Hits	39
SwissProt Accessions	P59047, Q86W29	Gene names	NALP5, MATER
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Mater protein homolog).

NAL11_HUMAN
NC score	0.944051 (rank : 10)	θ value	5.15425e-80 (rank : 11)
Query Neighborhood Hits	65	Target Neighborhood Hits	66	Shared Neighborhood Hits	30
SwissProt Accessions	P59045, Q53ZZ0, Q8NBF5	Gene names	NALP11, NOD17, PYPAF6
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 11 (PYRIN-containing APAF1-like protein 6) (Nucleotide-binding oligomerization domain protein 17).

NALP6_MOUSE
NC score	0.934865 (rank : 11)	θ value	1.84173e-61 (rank : 13)
Query Neighborhood Hits	65	Target Neighborhood Hits	55	Shared Neighborhood Hits	38
SwissProt Accessions	Q91WS2, Q8K0L4	Gene names	Nalp6, Pypaf5
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 6 (PYRIN-containing APAF1-like protein 5-like).

NALP6_HUMAN
NC score	0.933698 (rank : 12)	θ value	1.19377e-60 (rank : 14)
Query Neighborhood Hits	65	Target Neighborhood Hits	52	Shared Neighborhood Hits	37
SwissProt Accessions	P59044	Gene names	NALP6, PYPAF5
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 6 (PYRIN-containing APAF1-like protein 5).

NALP1_HUMAN
NC score	0.915250 (rank : 13)	θ value	3.34088e-79 (rank : 12)
Query Neighborhood Hits	65	Target Neighborhood Hits	138	Shared Neighborhood Hits	39
SwissProt Accessions	Q9C000, Q9BZZ8, Q9BZZ9, Q9HAV8, Q9UFT4, Q9Y2E0	Gene names	NALP1, CARD7, DEFCAP, KIAA0926, NAC
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 1 (Death effector filament- forming ced-4-like apoptosis protein) (Nucleotide-binding domain and caspase recruitment domain) (Caspase recruitment domain protein 7).

NAL10_HUMAN
NC score	0.903836 (rank : 14)	θ value	6.34462e-54 (rank : 15)
Query Neighborhood Hits	65	Target Neighborhood Hits	55	Shared Neighborhood Hits	33
SwissProt Accessions	Q86W26, Q6JGT0	Gene names	NALP10, NOD8, PYNOD
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 10 (Nucleotide-binding oligomerization domain protein 8).

NAL10_MOUSE
NC score	0.901681 (rank : 15)	θ value	1.61718e-49 (rank : 16)
Query Neighborhood Hits	65	Target Neighborhood Hits	46	Shared Neighborhood Hits	34
SwissProt Accessions	Q8CCN1	Gene names	Nalp10, Pynod
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 10.

NALP5_MOUSE
NC score	0.888263 (rank : 16)	θ value	2.45477e-106 (rank : 9)
Query Neighborhood Hits	65	Target Neighborhood Hits	560	Shared Neighborhood Hits	43
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

RINI_MOUSE
NC score	0.844254 (rank : 17)	θ value	1.24399e-33 (rank : 17)
Query Neighborhood Hits	65	Target Neighborhood Hits	87	Shared Neighborhood Hits	28
SwissProt Accessions	Q91VI7, Q924P4	Gene names	Rnh1, Rnh
Domain Architecture	No domain graphic available
Description	Ribonuclease inhibitor (Ribonuclease/angiogenin inhibitor 1).

RINI_HUMAN
NC score	0.843461 (rank : 18)	θ value	1.92365e-26 (rank : 18)
Query Neighborhood Hits	65	Target Neighborhood Hits	78	Shared Neighborhood Hits	28
SwissProt Accessions	P13489	Gene names	RNH1, PRI, RNH
Domain Architecture
Description	Ribonuclease inhibitor (Ribonuclease/angiogenin inhibitor 1) (RAI) (Placental ribonuclease inhibitor) (RNase inhibitor) (RI).

CAR15_MOUSE
NC score	0.745346 (rank : 19)	θ value	1.05554e-24 (rank : 19)
Query Neighborhood Hits	65	Target Neighborhood Hits	93	Shared Neighborhood Hits	37
SwissProt Accessions	Q8K3Z0	Gene names	Card15, Nod2
Domain Architecture
Description	Caspase recruitment domain-containing protein 15 (Protein Nod2).

CAR15_HUMAN
NC score	0.720065 (rank : 20)	θ value	1.68911e-14 (rank : 23)
Query Neighborhood Hits	65	Target Neighborhood Hits	77	Shared Neighborhood Hits	37
SwissProt Accessions	Q9HC29, Q96RH5, Q96RH6, Q96RH8	Gene names	CARD15, IBD1, NOD2
Domain Architecture
Description	Caspase recruitment domain-containing protein 15 (Protein Nod2) (Inflammatory bowel disease protein 1).

CARD4_MOUSE
NC score	0.708218 (rank : 21)	θ value	2.20094e-22 (rank : 21)
Query Neighborhood Hits	65	Target Neighborhood Hits	85	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BHB0, Q8BUT6	Gene names	Card4
Domain Architecture
Description	Caspase recruitment domain-containing protein 4.

CARD4_HUMAN
NC score	0.699467 (rank : 22)	θ value	1.29031e-22 (rank : 20)
Query Neighborhood Hits	65	Target Neighborhood Hits	102	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Y239, Q8IWF5	Gene names	CARD4, NOD1
Domain Architecture
Description	Caspase recruitment domain-containing protein 4 (Protein Nod1).

C2TA_MOUSE
NC score	0.644568 (rank : 23)	θ value	3.76295e-14 (rank : 24)
Query Neighborhood Hits	65	Target Neighborhood Hits	131	Shared Neighborhood Hits	36
SwissProt Accessions	P79621, O46787, O78036, O78109, Q31115, Q9TPP1	Gene names	Ciita, C2ta, Mhc2ta
Domain Architecture
Description	MHC class II transactivator (CIITA).

C2TA_HUMAN
NC score	0.628721 (rank : 24)	θ value	1.058e-16 (rank : 22)
Query Neighborhood Hits	65	Target Neighborhood Hits	190	Shared Neighborhood Hits	30
SwissProt Accessions	P33076	Gene names	CIITA, MHC2TA
Domain Architecture
Description	MHC class II transactivator (CIITA).

LRC34_HUMAN
NC score	0.547993 (rank : 25)	θ value	3.89403e-11 (rank : 25)
Query Neighborhood Hits	65	Target Neighborhood Hits	67	Shared Neighborhood Hits	27
SwissProt Accessions	Q8IZ02	Gene names	LRRC34
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 34.

LRC34_MOUSE
NC score	0.505973 (rank : 26)	θ value	2.44474e-05 (rank : 30)
Query Neighborhood Hits	65	Target Neighborhood Hits	58	Shared Neighborhood Hits	26
SwissProt Accessions	Q9DAM1	Gene names	Lrrc34
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 34.

LRC31_HUMAN
NC score	0.486732 (rank : 27)	θ value	0.00102713 (rank : 33)
Query Neighborhood Hits	65	Target Neighborhood Hits	139	Shared Neighborhood Hits	32
SwissProt Accessions	Q6UY01, Q8N848, Q9H5N5	Gene names	LRRC31
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 31.

CF154_HUMAN
NC score	0.469071 (rank : 28)	θ value	0.813845 (rank : 39)
Query Neighborhood Hits	65	Target Neighborhood Hits	36	Shared Neighborhood Hits	25
SwissProt Accessions	Q5JTD7	Gene names	C6orf154
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf154.

CAR12_HUMAN
NC score	0.355264 (rank : 29)	θ value	0.0193708 (rank : 35)
Query Neighborhood Hits	65	Target Neighborhood Hits	132	Shared Neighborhood Hits	34
SwissProt Accessions	Q9NPP4, Q96J81, Q96J82, Q96J83	Gene names	CARD12, CLAN, CLAN1
Domain Architecture
Description	Caspase recruitment domain-containing protein 12 (Ice protease- activating factor) (Ipaf) (CARD, LRR, and NACHT-containing protein) (Clan protein).

RGP1_HUMAN
NC score	0.301098 (rank : 30)	θ value	θ > 10 (rank : 79)
Query Neighborhood Hits	65	Target Neighborhood Hits	124	Shared Neighborhood Hits	23
SwissProt Accessions	P46060	Gene names	RANGAP1
Domain Architecture
Description	Ran GTPase-activating protein 1.

ASC_MOUSE
NC score	0.292250 (rank : 31)	θ value	0.00665767 (rank : 34)
Query Neighborhood Hits	65	Target Neighborhood Hits	17	Shared Neighborhood Hits	15
SwissProt Accessions	Q9EPB4, Q9D2W9	Gene names	Pycard, Asc
Domain Architecture
Description	Apoptosis-associated speck-like protein containing a CARD (mASC) (PYD and CARD domain-containing protein).

RGP1_MOUSE
NC score	0.286968 (rank : 32)	θ value	θ > 10 (rank : 80)
Query Neighborhood Hits	65	Target Neighborhood Hits	105	Shared Neighborhood Hits	23
SwissProt Accessions	P46061, Q60801	Gene names	Rangap1, Fug1
Domain Architecture
Description	Ran GTPase-activating protein 1.

BIRC1_HUMAN
NC score	0.279722 (rank : 33)	θ value	1.29631e-06 (rank : 26)
Query Neighborhood Hits	65	Target Neighborhood Hits	61	Shared Neighborhood Hits	31
SwissProt Accessions	Q13075, O75857, Q13730, Q99796	Gene names	BIRC1, NAIP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1 (Neuronal apoptosis inhibitory protein).

BIR1A_MOUSE
NC score	0.259416 (rank : 34)	θ value	4.1701e-05 (rank : 31)
Query Neighborhood Hits	65	Target Neighborhood Hits	94	Shared Neighborhood Hits	27
SwissProt Accessions	Q9QWK5, Q9JIB5, Q9R017	Gene names	Birc1a, Naip, Naip1
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1a (Neuronal apoptosis inhibitory protein 1).

BIR1F_MOUSE
NC score	0.255954 (rank : 35)	θ value	2.88788e-06 (rank : 28)
Query Neighborhood Hits	65	Target Neighborhood Hits	88	Shared Neighborhood Hits	28
SwissProt Accessions	Q9JIB6, O09121, O09122, P81704	Gene names	Birc1f, Naip-rs4, Naip6
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1f (Neuronal apoptosis inhibitory protein 6).

BIR1E_MOUSE
NC score	0.254121 (rank : 36)	θ value	1.69304e-06 (rank : 27)
Query Neighborhood Hits	65	Target Neighborhood Hits	93	Shared Neighborhood Hits	27
SwissProt Accessions	Q9R016, O09121, O09122, P81703, Q9R029	Gene names	Birc1e, Naip-rs3, Naip5
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1e (Neuronal apoptosis inhibitory protein 5).

BIR1G_MOUSE
NC score	0.248712 (rank : 37)	θ value	2.88788e-06 (rank : 29)
Query Neighborhood Hits	65	Target Neighborhood Hits	92	Shared Neighborhood Hits	27
SwissProt Accessions	Q9JIB3	Gene names	Birc1g, Naip7
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1g (Neuronal apoptosis inhibitory protein 7).

BIR1B_MOUSE
NC score	0.239949 (rank : 38)	θ value	0.000461057 (rank : 32)
Query Neighborhood Hits	65	Target Neighborhood Hits	93	Shared Neighborhood Hits	29
SwissProt Accessions	Q9QUK4, O09124, Q9R030	Gene names	Birc1b, Naip-rs6, Naip2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1b (Neuronal apoptosis inhibitory protein 2).

ASC_HUMAN
NC score	0.224778 (rank : 39)	θ value	3.0926 (rank : 46)
Query Neighborhood Hits	65	Target Neighborhood Hits	18	Shared Neighborhood Hits	14
SwissProt Accessions	Q9ULZ3, Q96D12, Q9BSZ5, Q9HBD0, Q9NXJ8	Gene names	PYCARD, ASC, CARD5, TMS1
Domain Architecture
Description	Apoptosis-associated speck-like protein containing a CARD (hASC) (PYD and CARD domain-containing protein) (Target of methylation-induced silencing 1) (Caspase recruitment domain-containing protein 5).

LRC45_MOUSE
NC score	0.160165 (rank : 40)	θ value	1.38821 (rank : 41)
Query Neighborhood Hits	65	Target Neighborhood Hits	959	Shared Neighborhood Hits	30
SwissProt Accessions	Q8CIM1, Q3U5Z2	Gene names	Lrrc45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

LRC45_HUMAN
NC score	0.148034 (rank : 41)	θ value	θ > 10 (rank : 77)
Query Neighborhood Hits	65	Target Neighborhood Hits	933	Shared Neighborhood Hits	29
SwissProt Accessions	Q96CN5	Gene names	LRRC45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

MEFV_MOUSE
NC score	0.141454 (rank : 42)	θ value	5.27518 (rank : 55)
Query Neighborhood Hits	65	Target Neighborhood Hits	236	Shared Neighborhood Hits	18
SwissProt Accessions	Q9JJ26	Gene names	Mefv
Domain Architecture
Description	Pyrin (Marenostrin).

CARD8_HUMAN
NC score	0.117084 (rank : 43)	θ value	θ > 10 (rank : 74)
Query Neighborhood Hits	65	Target Neighborhood Hits	22	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y2G2, Q6PGP8, Q96P82	Gene names	CARD8, KIAA0955, NDPP1
Domain Architecture
Description	Caspase recruitment domain-containing protein 8 (Apoptotic protein NDPP1) (DACAR) (CARD-inhibitor of NF-kappa-B-activating ligand) (CARDINAL) (Tumor-up-regulated CARD-containing antagonist of CASP9) (TUCAN).

LRC14_HUMAN
NC score	0.082107 (rank : 44)	θ value	θ > 10 (rank : 76)
Query Neighborhood Hits	65	Target Neighborhood Hits	57	Shared Neighborhood Hits	16
SwissProt Accessions	Q15048	Gene names	LRRC14, KIAA0014
Domain Architecture
Description	Leucine-rich repeat-containing protein 14.

MEFV_HUMAN
NC score	0.081250 (rank : 45)	θ value	1.06291 (rank : 40)
Query Neighborhood Hits	65	Target Neighborhood Hits	431	Shared Neighborhood Hits	16
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

BIRC2_MOUSE
NC score	0.058920 (rank : 46)	θ value	θ > 10 (rank : 67)
Query Neighborhood Hits	65	Target Neighborhood Hits	137	Shared Neighborhood Hits	10
SwissProt Accessions	Q62210, O08864	Gene names	Birc2, Birc3, Iap2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (MIAP2) (MIAP-2).

BIRC2_HUMAN
NC score	0.057956 (rank : 47)	θ value	θ > 10 (rank : 66)
Query Neighborhood Hits	65	Target Neighborhood Hits	142	Shared Neighborhood Hits	9
SwissProt Accessions	Q13490, Q16516, Q4TTG0	Gene names	BIRC2, API1, IAP2, MIHB
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (HIAP2) (HIAP-2) (C-IAP1) (TNFR2-TRAF signaling complex protein 2) (IAP homolog B).

BIRC4_MOUSE
NC score	0.055585 (rank : 48)	θ value	θ > 10 (rank : 71)
Query Neighborhood Hits	65	Target Neighborhood Hits	89	Shared Neighborhood Hits	6
SwissProt Accessions	Q60989, O08865	Gene names	Birc4, Aipa, Api3, Miha, Xiap
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 4 (Inhibitor of apoptosis protein 3) (X-linked inhibitor of apoptosis protein) (X-linked IAP) (IAP homolog A) (MIAP3) (MIAP-3).

BIRC4_HUMAN
NC score	0.054412 (rank : 49)	θ value	θ > 10 (rank : 70)
Query Neighborhood Hits	65	Target Neighborhood Hits	89	Shared Neighborhood Hits	6
SwissProt Accessions	P98170, Q9NQ14	Gene names	BIRC4, API3, IAP3, XIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 4 (Inhibitor of apoptosis protein 3) (X-linked inhibitor of apoptosis protein) (X-linked IAP) (IAP-like protein) (HILP).

MAPE_HUMAN
NC score	0.052734 (rank : 50)	θ value	θ > 10 (rank : 78)
Query Neighborhood Hits	65	Target Neighborhood Hits	24	Shared Neighborhood Hits	9
SwissProt Accessions	P78395, O43481, Q8IXN8	Gene names	PRAME, MAPE
Domain Architecture	No domain graphic available
Description	Melanoma antigen preferentially expressed in tumors (Preferentially expressed antigen of melanoma) (OPA-interacting protein 4) (OIP4).

BIRC5_HUMAN
NC score	0.052462 (rank : 51)	θ value	θ > 10 (rank : 72)
Query Neighborhood Hits	65	Target Neighborhood Hits	20	Shared Neighborhood Hits	6
SwissProt Accessions	O15392, Q2I3N8, Q4VGX0, Q53F61, Q5MGC6, Q6FHL2, Q75SP2, Q9P2W8	Gene names	BIRC5, API4, IAP4
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 5 (Apoptosis inhibitor survivin) (Apoptosis inhibitor 4).

BIRC3_HUMAN
NC score	0.052415 (rank : 52)	θ value	θ > 10 (rank : 68)
Query Neighborhood Hits	65	Target Neighborhood Hits	133	Shared Neighborhood Hits	7
SwissProt Accessions	Q13489, Q16628, Q9HC27, Q9UP46	Gene names	BIRC3, API2, IAP1, MIHC
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (HIAP1) (HIAP-1) (C-IAP2) (TNFR2-TRAF signaling complex protein 1) (IAP homolog C) (Apoptosis inhibitor 2) (API2).

BIRC3_MOUSE
NC score	0.052038 (rank : 53)	θ value	θ > 10 (rank : 69)
Query Neighborhood Hits	65	Target Neighborhood Hits	113	Shared Neighborhood Hits	6
SwissProt Accessions	O08863	Gene names	Birc3, Birc2, Iap1
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (MIAP1) (MIAP-1).

BIRC5_MOUSE
NC score	0.051538 (rank : 54)	θ value	θ > 10 (rank : 73)
Query Neighborhood Hits	65	Target Neighborhood Hits	19	Shared Neighborhood Hits	6
SwissProt Accessions	O70201, Q923F7, Q9WU53, Q9WU54	Gene names	Birc5, Api4, Iap4
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 5 (Apoptosis inhibitor survivin) (Apoptosis inhibitor 4) (TIAP).

CD14_MOUSE
NC score	0.050947 (rank : 55)	θ value	θ > 10 (rank : 75)
Query Neighborhood Hits	65	Target Neighborhood Hits	104	Shared Neighborhood Hits	7
SwissProt Accessions	P10810	Gene names	Cd14
Domain Architecture
Description	Monocyte differentiation antigen CD14 precursor (Myeloid cell-specific leucine-rich glycoprotein).

CLPX_HUMAN
NC score	0.029716 (rank : 56)	θ value	5.27518 (rank : 51)
Query Neighborhood Hits	65	Target Neighborhood Hits	72	Shared Neighborhood Hits	12
SwissProt Accessions	O76031, Q9H4D9	Gene names	CLPX
Domain Architecture
Description	ATP-dependent Clp protease ATP-binding subunit ClpX-like, mitochondrial precursor.

PEO1_HUMAN
NC score	0.029406 (rank : 57)	θ value	0.62314 (rank : 38)
Query Neighborhood Hits	65	Target Neighborhood Hits	18	Shared Neighborhood Hits	5
SwissProt Accessions	Q96RR1, Q6MZX2, Q96RR0	Gene names	PEO1, C10orf2
Domain Architecture	No domain graphic available
Description	Twinkle protein, mitochondrial precursor (EC 3.6.1.-) (T7 gp4-like protein with intramitochondrial nucleoid localization) (T7-like mitochondrial DNA helicase) (Progressive external ophthalmoplegia 1 protein).

PEO1_MOUSE
NC score	0.026117 (rank : 58)	θ value	3.0926 (rank : 47)
Query Neighborhood Hits	65	Target Neighborhood Hits	27	Shared Neighborhood Hits	6
SwissProt Accessions	Q8CIW5, Q8K1Z1	Gene names	Peo1
Domain Architecture	No domain graphic available
Description	Twinkle protein, mitochondrial precursor (EC 3.6.1.-) (T7 gp4-like protein with intramitochondrial nucleoid localization) (T7-like mitochondrial DNA helicase) (Progressive external ophthalmoplegia 1 protein homolog).

TRP13_MOUSE
NC score	0.025003 (rank : 59)	θ value	3.0926 (rank : 49)
Query Neighborhood Hits	65	Target Neighborhood Hits	81	Shared Neighborhood Hits	12
SwissProt Accessions	Q3UA06, Q3UQG6, Q9CWW8	Gene names	Trip13
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 13 (Thyroid hormone receptor interactor 13) (Trip-13).

TRP13_HUMAN
NC score	0.023737 (rank : 60)	θ value	5.27518 (rank : 56)
Query Neighborhood Hits	65	Target Neighborhood Hits	81	Shared Neighborhood Hits	13
SwissProt Accessions	Q15645, O15324	Gene names	TRIP13
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 13 (Thyroid hormone receptor interactor 13) (Trip-13) (Human papillomavirus type 16 E1 protein- binding protein) (HPV16 E1 protein-binding protein) (16E1-BP).

CLPX_MOUSE
NC score	0.022344 (rank : 61)	θ value	8.99809 (rank : 60)
Query Neighborhood Hits	65	Target Neighborhood Hits	73	Shared Neighborhood Hits	11
SwissProt Accessions	Q9JHS4, Q9WVD1	Gene names	Clpx
Domain Architecture
Description	ATP-dependent Clp protease ATP-binding subunit ClpX-like, mitochondrial precursor.

BMS1_HUMAN
NC score	0.021475 (rank : 62)	θ value	5.27518 (rank : 50)
Query Neighborhood Hits	65	Target Neighborhood Hits	109	Shared Neighborhood Hits	3
SwissProt Accessions	Q14692, Q86XJ9	Gene names	BMS1L, KIAA0187
Domain Architecture
Description	Ribosome biogenesis protein BMS1 homolog.

NVL_MOUSE
NC score	0.020852 (rank : 63)	θ value	0.365318 (rank : 37)
Query Neighborhood Hits	65	Target Neighborhood Hits	110	Shared Neighborhood Hits	15
SwissProt Accessions	Q9DBY8, Q3USC4, Q8BW27, Q8K2B5	Gene names	Nvl
Domain Architecture
Description	Nuclear valosin-containing protein-like (Nuclear VCP-like protein) (NVLp).

PEX6_HUMAN
NC score	0.020078 (rank : 64)	θ value	1.38821 (rank : 42)
Query Neighborhood Hits	65	Target Neighborhood Hits	99	Shared Neighborhood Hits	14
SwissProt Accessions	Q13608, Q8WYQ2, Q99476	Gene names	PEX6, PXAAA1
Domain Architecture
Description	Peroxisome assembly factor 2 (PAF-2) (Peroxisomal-type ATPase 1) (Peroxin-6) (Peroxisomal biogenesis factor 6).

PEX6_MOUSE
NC score	0.020059 (rank : 65)	θ value	1.38821 (rank : 43)
Query Neighborhood Hits	65	Target Neighborhood Hits	94	Shared Neighborhood Hits	14
SwissProt Accessions	Q99LC9, Q6YNQ9	Gene names	Pex6
Domain Architecture	No domain graphic available
Description	Peroxisome assembly factor 2 (PAF-2) (Peroxisomal-type ATPase 1) (Peroxin-6) (Peroxisomal biogenesis factor 6).

NVL_HUMAN
NC score	0.016579 (rank : 66)	θ value	8.99809 (rank : 63)
Query Neighborhood Hits	65	Target Neighborhood Hits	112	Shared Neighborhood Hits	14
SwissProt Accessions	O15381, Q96EM7	Gene names	NVL
Domain Architecture
Description	Nuclear valosin-containing protein-like (Nuclear VCP-like protein) (NVLp).

CENPB_MOUSE
NC score	0.015981 (rank : 67)	θ value	8.99809 (rank : 58)
Query Neighborhood Hits	65	Target Neighborhood Hits	163	Shared Neighborhood Hits	4
SwissProt Accessions	P27790	Gene names	Cenpb, Cenp-b
Domain Architecture
Description	Major centromere autoantigen B (Centromere protein B) (CENP-B).

PNPO_MOUSE
NC score	0.015712 (rank : 68)	θ value	3.0926 (rank : 48)
Query Neighborhood Hits	65	Target Neighborhood Hits	4	Shared Neighborhood Hits	2
SwissProt Accessions	Q91XF0	Gene names	Pnpo
Domain Architecture
Description	Pyridoxine-5'-phosphate oxidase (EC 1.4.3.5) (Pyridoxamine-phosphate oxidase).

VPS4B_MOUSE
NC score	0.011314 (rank : 69)	θ value	5.27518 (rank : 57)
Query Neighborhood Hits	65	Target Neighborhood Hits	86	Shared Neighborhood Hits	12
SwissProt Accessions	P46467, Q91W22, Q9R1C9	Gene names	Vps4b, Skd1
Domain Architecture
Description	Vacuolar protein sorting-associating protein 4B (Protein SKD1).

PRS10_HUMAN
NC score	0.010805 (rank : 70)	θ value	8.99809 (rank : 64)
Query Neighborhood Hits	65	Target Neighborhood Hits	95	Shared Neighborhood Hits	12
SwissProt Accessions	P62333, P49719, Q6IBU3, Q92524	Gene names	PSMC6, SUG2
Domain Architecture
Description	26S protease regulatory subunit S10B (Proteasome subunit p42) (Proteasome 26S subunit ATPase 6).

PRS10_MOUSE
NC score	0.010805 (rank : 71)	θ value	8.99809 (rank : 65)
Query Neighborhood Hits	65	Target Neighborhood Hits	95	Shared Neighborhood Hits	12
SwissProt Accessions	P62334, P49719, Q3TKK1, Q810A6, Q92524, Q9CXH9	Gene names	Psmc6, Sug2
Domain Architecture
Description	26S protease regulatory subunit S10B (Proteasome subunit p42) (Proteasome 26S subunit ATPase 6).

KGUA_MOUSE
NC score	0.010065 (rank : 72)	θ value	8.99809 (rank : 62)
Query Neighborhood Hits	65	Target Neighborhood Hits	45	Shared Neighborhood Hits	4
SwissProt Accessions	Q64520	Gene names	Guk1, Gmk
Domain Architecture
Description	Guanylate kinase (EC 2.7.4.8) (GMP kinase).

DIRA3_HUMAN
NC score	0.007173 (rank : 73)	θ value	8.99809 (rank : 61)
Query Neighborhood Hits	65	Target Neighborhood Hits	241	Shared Neighborhood Hits	7
SwissProt Accessions	O95661	Gene names	DIRAS3, ARHI, NOEY2, RHOI
Domain Architecture
Description	GTP-binding protein Di-Ras3 (Distinct subgroup of the Ras family member 3) (Rho-related GTP-binding protein RhoI).

DHX57_HUMAN
NC score	0.006527 (rank : 74)	θ value	5.27518 (rank : 52)
Query Neighborhood Hits	65	Target Neighborhood Hits	109	Shared Neighborhood Hits	5
SwissProt Accessions	Q6P158, Q53SI4, Q6P9G1, Q7Z6H3, Q8NG17, Q96M33	Gene names	DHX57
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX57 (EC 3.6.1.-) (DEAH box protein 57).

DHX57_MOUSE
NC score	0.006496 (rank : 75)	θ value	5.27518 (rank : 53)
Query Neighborhood Hits	65	Target Neighborhood Hits	125	Shared Neighborhood Hits	5
SwissProt Accessions	Q6P5D3, Q3TS93, Q6NZK4, Q6P1B4, Q8BI63, Q8BIA2, Q8R360	Gene names	Dhx57
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX57 (EC 3.6.1.-) (DEAH box protein 57).

CP250_MOUSE
NC score	0.005364 (rank : 76)	θ value	0.365318 (rank : 36)
Query Neighborhood Hits	65	Target Neighborhood Hits	1583	Shared Neighborhood Hits	7
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

CP250_HUMAN
NC score	0.001893 (rank : 77)	θ value	2.36792 (rank : 44)
Query Neighborhood Hits	65	Target Neighborhood Hits	1805	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

CK5P2_HUMAN
NC score	0.001339 (rank : 78)	θ value	8.99809 (rank : 59)
Query Neighborhood Hits	65	Target Neighborhood Hits	1433	Shared Neighborhood Hits	7
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

LRIG3_MOUSE
NC score	-0.000680 (rank : 79)	θ value	5.27518 (rank : 54)
Query Neighborhood Hits	65	Target Neighborhood Hits	611	Shared Neighborhood Hits	5
SwissProt Accessions	Q6P1C6, Q6ZPE6, Q8BRF0, Q8BS51, Q8C5E4	Gene names	Lrig3, Kiaa3016
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 3 precursor.

ZNF35_HUMAN
NC score	-0.003495 (rank : 80)	θ value	2.36792 (rank : 45)
Query Neighborhood Hits	65	Target Neighborhood Hits	761	Shared Neighborhood Hits	3
SwissProt Accessions	P13682, Q96D01	Gene names	ZNF35
Domain Architecture	No domain graphic available
Description	Zinc finger protein 35 (Zinc finger protein HF.10).