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Network neighborhood for query Sequence : RINI_HUMAN

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RINI_HUMAN
SwissProt Accessions	P13489	Gene names	RNH1, PRI, RNH
Domain Architecture
Description	Ribonuclease inhibitor (Ribonuclease/angiogenin inhibitor 1) (RAI) (Placental ribonuclease inhibitor) (RNase inhibitor) (RI).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

RINI_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	78	Target Neighborhood Hits	78	Shared Neighborhood Hits	78
SwissProt Accessions	P13489	Gene names	RNH1, PRI, RNH
Domain Architecture
Description	Ribonuclease inhibitor (Ribonuclease/angiogenin inhibitor 1) (RAI) (Placental ribonuclease inhibitor) (RNase inhibitor) (RI).

RINI_MOUSE
θ value	0 (rank : 2)	NC score	0.983557 (rank : 2)
Query Neighborhood Hits	78	Target Neighborhood Hits	87	Shared Neighborhood Hits	49
SwissProt Accessions	Q91VI7, Q924P4	Gene names	Rnh1, Rnh
Domain Architecture	No domain graphic available
Description	Ribonuclease inhibitor (Ribonuclease/angiogenin inhibitor 1).

NAL12_HUMAN
θ value	5.51964e-74 (rank : 3)	NC score	0.886462 (rank : 5)
Query Neighborhood Hits	78	Target Neighborhood Hits	96	Shared Neighborhood Hits	43
SwissProt Accessions	P59046, Q8NEU4, Q9BY26	Gene names	NALP12, PYPAF7, RNO
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 12 (PYRIN-containing APAF1-like protein 7) (Monarch-1) (Regulated by nitric oxide).

NALP5_HUMAN
θ value	8.55514e-59 (rank : 4)	NC score	0.902444 (rank : 3)
Query Neighborhood Hits	78	Target Neighborhood Hits	88	Shared Neighborhood Hits	40
SwissProt Accessions	P59047, Q86W29	Gene names	NALP5, MATER
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Mater protein homolog).

CIAS1_MOUSE
θ value	1.78386e-56 (rank : 5)	NC score	0.878050 (rank : 8)
Query Neighborhood Hits	78	Target Neighborhood Hits	67	Shared Neighborhood Hits	35
SwissProt Accessions	Q8R4B8, Q6JEL0	Gene names	Cias1, Mmig1, Nalp3, Pypaf1
Domain Architecture
Description	Cold autoinflammatory syndrome 1 protein homolog (PYRIN-containing APAF1-like protein 1) (Mast cell maturation-associated-inducible protein 1) (Cryopyrin).

NAL14_HUMAN
θ value	8.85319e-56 (rank : 6)	NC score	0.892489 (rank : 4)
Query Neighborhood Hits	78	Target Neighborhood Hits	76	Shared Neighborhood Hits	37
SwissProt Accessions	Q86W24, Q7RTR6	Gene names	NALP14, NOD5
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 14 (Nucleotide-binding oligomerization domain protein 5).

CIAS1_HUMAN
θ value	6.34462e-54 (rank : 7)	NC score	0.872956 (rank : 11)
Query Neighborhood Hits	78	Target Neighborhood Hits	76	Shared Neighborhood Hits	36
SwissProt Accessions	Q96P20, O75434, Q59H68, Q5JQS8, Q5JQS9, Q6TG35, Q8TCW0, Q8TEU9, Q8WXH9	Gene names	CIAS1, NALP3, PYPAF1
Domain Architecture
Description	Cold autoinflammatory syndrome 1 protein (Cryopyrin) (NACHT-, LRR- and PYD-containing protein 3) (PYRIN-containing APAF1-like protein 1) (Angiotensin/vasopressin receptor AII/AVP-like).

NAL11_HUMAN
θ value	3.04986e-48 (rank : 8)	NC score	0.885689 (rank : 6)
Query Neighborhood Hits	78	Target Neighborhood Hits	66	Shared Neighborhood Hits	38
SwissProt Accessions	P59045, Q53ZZ0, Q8NBF5	Gene names	NALP11, NOD17, PYPAF6
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 11 (PYRIN-containing APAF1-like protein 6) (Nucleotide-binding oligomerization domain protein 17).

NALP5_MOUSE
θ value	2.85459e-46 (rank : 9)	NC score	0.835630 (rank : 13)
Query Neighborhood Hits	78	Target Neighborhood Hits	560	Shared Neighborhood Hits	40
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

NALP2_HUMAN
θ value	9.18288e-45 (rank : 10)	NC score	0.874853 (rank : 10)
Query Neighborhood Hits	78	Target Neighborhood Hits	65	Shared Neighborhood Hits	35
SwissProt Accessions	Q9NX02, Q53FL5, Q59G09, Q8IXT0, Q9BVN5, Q9H6G6, Q9HAV9, Q9NWK3	Gene names	NALP2, NBS1, PAN1, PYPAF2
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 2 (PYRIN domain and NACHT domain-containing protein 1) (PYRIN-containing APAF1-like protein 2) (Nucleotide-binding site protein 1).

NAL13_HUMAN
θ value	1.32601e-43 (rank : 11)	NC score	0.884687 (rank : 7)
Query Neighborhood Hits	78	Target Neighborhood Hits	93	Shared Neighborhood Hits	34
SwissProt Accessions	Q86W25, Q7RTR5	Gene names	NALP13, NOD14
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 13 (Nucleotide-binding oligomerization domain protein 14).

NALP4_HUMAN
θ value	6.58091e-43 (rank : 12)	NC score	0.876642 (rank : 9)
Query Neighborhood Hits	78	Target Neighborhood Hits	81	Shared Neighborhood Hits	37
SwissProt Accessions	Q96MN2, Q86W87, Q96AY6	Gene names	NALP4, PAN2, PYPAF4, RNH2
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 4 (PYRIN-containing APAF1-like protein 4) (PAAD and NACHT-containing protein 2) (PYRIN and NACHT- containing protein 2) (Ribonuclease inhibitor 2).

NALP1_HUMAN
θ value	2.12192e-33 (rank : 13)	NC score	0.816649 (rank : 14)
Query Neighborhood Hits	78	Target Neighborhood Hits	138	Shared Neighborhood Hits	40
SwissProt Accessions	Q9C000, Q9BZZ8, Q9BZZ9, Q9HAV8, Q9UFT4, Q9Y2E0	Gene names	NALP1, CARD7, DEFCAP, KIAA0926, NAC
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 1 (Death effector filament- forming ced-4-like apoptosis protein) (Nucleotide-binding domain and caspase recruitment domain) (Caspase recruitment domain protein 7).

NALP7_HUMAN
θ value	1.92365e-26 (rank : 14)	NC score	0.843461 (rank : 12)
Query Neighborhood Hits	78	Target Neighborhood Hits	65	Shared Neighborhood Hits	28
SwissProt Accessions	Q8WX94, Q7RTR1	Gene names	NALP7, NOD12, PYPAF3
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 7 (PYRIN-containing APAF1-like protein 3).

LRC31_HUMAN
θ value	5.99374e-20 (rank : 15)	NC score	0.624865 (rank : 23)
Query Neighborhood Hits	78	Target Neighborhood Hits	139	Shared Neighborhood Hits	41
SwissProt Accessions	Q6UY01, Q8N848, Q9H5N5	Gene names	LRRC31
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 31.

NALP6_MOUSE
θ value	2.13179e-17 (rank : 16)	NC score	0.779237 (rank : 15)
Query Neighborhood Hits	78	Target Neighborhood Hits	55	Shared Neighborhood Hits	28
SwissProt Accessions	Q91WS2, Q8K0L4	Gene names	Nalp6, Pypaf5
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 6 (PYRIN-containing APAF1-like protein 5-like).

CARD4_HUMAN
θ value	3.63628e-17 (rank : 17)	NC score	0.706501 (rank : 18)
Query Neighborhood Hits	78	Target Neighborhood Hits	102	Shared Neighborhood Hits	46
SwissProt Accessions	Q9Y239, Q8IWF5	Gene names	CARD4, NOD1
Domain Architecture
Description	Caspase recruitment domain-containing protein 4 (Protein Nod1).

NALP6_HUMAN
θ value	1.16975e-15 (rank : 18)	NC score	0.774969 (rank : 16)
Query Neighborhood Hits	78	Target Neighborhood Hits	52	Shared Neighborhood Hits	26
SwissProt Accessions	P59044	Gene names	NALP6, PYPAF5
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 6 (PYRIN-containing APAF1-like protein 5).

CARD4_MOUSE
θ value	1.52774e-15 (rank : 19)	NC score	0.699647 (rank : 20)
Query Neighborhood Hits	78	Target Neighborhood Hits	85	Shared Neighborhood Hits	41
SwissProt Accessions	Q8BHB0, Q8BUT6	Gene names	Card4
Domain Architecture
Description	Caspase recruitment domain-containing protein 4.

CAR15_MOUSE
θ value	1.99529e-15 (rank : 20)	NC score	0.708307 (rank : 17)
Query Neighborhood Hits	78	Target Neighborhood Hits	93	Shared Neighborhood Hits	46
SwissProt Accessions	Q8K3Z0	Gene names	Card15, Nod2
Domain Architecture
Description	Caspase recruitment domain-containing protein 15 (Protein Nod2).

CAR15_HUMAN
θ value	5.8054e-15 (rank : 21)	NC score	0.701214 (rank : 19)
Query Neighborhood Hits	78	Target Neighborhood Hits	77	Shared Neighborhood Hits	43
SwissProt Accessions	Q9HC29, Q96RH5, Q96RH6, Q96RH8	Gene names	CARD15, IBD1, NOD2
Domain Architecture
Description	Caspase recruitment domain-containing protein 15 (Protein Nod2) (Inflammatory bowel disease protein 1).

CF154_HUMAN
θ value	2.79066e-09 (rank : 22)	NC score	0.615202 (rank : 25)
Query Neighborhood Hits	78	Target Neighborhood Hits	36	Shared Neighborhood Hits	29
SwissProt Accessions	Q5JTD7	Gene names	C6orf154
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf154.

LRC34_MOUSE
θ value	1.06045e-08 (rank : 23)	NC score	0.593435 (rank : 26)
Query Neighborhood Hits	78	Target Neighborhood Hits	58	Shared Neighborhood Hits	38
SwissProt Accessions	Q9DAM1	Gene names	Lrrc34
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 34.

LRC45_MOUSE
θ value	1.17247e-07 (rank : 24)	NC score	0.221869 (rank : 32)
Query Neighborhood Hits	78	Target Neighborhood Hits	959	Shared Neighborhood Hits	45
SwissProt Accessions	Q8CIM1, Q3U5Z2	Gene names	Lrrc45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

RGP1_HUMAN
θ value	2.88788e-06 (rank : 25)	NC score	0.443924 (rank : 29)
Query Neighborhood Hits	78	Target Neighborhood Hits	124	Shared Neighborhood Hits	26
SwissProt Accessions	P46060	Gene names	RANGAP1
Domain Architecture
Description	Ran GTPase-activating protein 1.

LRC34_HUMAN
θ value	6.43352e-06 (rank : 26)	NC score	0.618621 (rank : 24)
Query Neighborhood Hits	78	Target Neighborhood Hits	67	Shared Neighborhood Hits	39
SwissProt Accessions	Q8IZ02	Gene names	LRRC34
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 34.

LRC45_HUMAN
θ value	6.43352e-06 (rank : 27)	NC score	0.210018 (rank : 33)
Query Neighborhood Hits	78	Target Neighborhood Hits	933	Shared Neighborhood Hits	38
SwissProt Accessions	Q96CN5	Gene names	LRRC45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

RGP1_MOUSE
θ value	1.87187e-05 (rank : 28)	NC score	0.425153 (rank : 30)
Query Neighborhood Hits	78	Target Neighborhood Hits	105	Shared Neighborhood Hits	27
SwissProt Accessions	P46061, Q60801	Gene names	Rangap1, Fug1
Domain Architecture
Description	Ran GTPase-activating protein 1.

CAR12_HUMAN
θ value	4.1701e-05 (rank : 29)	NC score	0.297515 (rank : 31)
Query Neighborhood Hits	78	Target Neighborhood Hits	132	Shared Neighborhood Hits	39
SwissProt Accessions	Q9NPP4, Q96J81, Q96J82, Q96J83	Gene names	CARD12, CLAN, CLAN1
Domain Architecture
Description	Caspase recruitment domain-containing protein 12 (Ice protease- activating factor) (Ipaf) (CARD, LRR, and NACHT-containing protein) (Clan protein).

C2TA_MOUSE
θ value	0.00020696 (rank : 30)	NC score	0.534582 (rank : 27)
Query Neighborhood Hits	78	Target Neighborhood Hits	131	Shared Neighborhood Hits	45
SwissProt Accessions	P79621, O46787, O78036, O78109, Q31115, Q9TPP1	Gene names	Ciita, C2ta, Mhc2ta
Domain Architecture
Description	MHC class II transactivator (CIITA).

C2TA_HUMAN
θ value	0.00298849 (rank : 31)	NC score	0.519191 (rank : 28)
Query Neighborhood Hits	78	Target Neighborhood Hits	190	Shared Neighborhood Hits	37
SwissProt Accessions	P33076	Gene names	CIITA, MHC2TA
Domain Architecture
Description	MHC class II transactivator (CIITA).

LRC42_MOUSE
θ value	0.00665767 (rank : 32)	NC score	0.104141 (rank : 44)
Query Neighborhood Hits	78	Target Neighborhood Hits	25	Shared Neighborhood Hits	8
SwissProt Accessions	Q8R2U7, Q3TE62, Q9CTP9	Gene names	Lrrc42
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 42.

A2GL_HUMAN
θ value	0.0330416 (rank : 33)	NC score	0.035367 (rank : 78)
Query Neighborhood Hits	78	Target Neighborhood Hits	281	Shared Neighborhood Hits	28
SwissProt Accessions	P02750, Q8N4F5, Q96QZ4	Gene names	LRG1, LRG
Domain Architecture
Description	Leucine-rich alpha-2-glycoprotein precursor (LRG).

LRC42_HUMAN
θ value	0.0330416 (rank : 34)	NC score	0.084149 (rank : 52)
Query Neighborhood Hits	78	Target Neighborhood Hits	26	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y546, Q8N2Q8	Gene names	LRRC42
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 42.

TBCEL_HUMAN
θ value	0.0431538 (rank : 35)	NC score	0.065972 (rank : 60)
Query Neighborhood Hits	78	Target Neighborhood Hits	89	Shared Neighborhood Hits	11
SwissProt Accessions	Q5QJ74	Gene names	LRRC35
Domain Architecture	No domain graphic available
Description	Tubulin-specific chaperone cofactor E-like protein (Leucine-rich repeat-containing protein 35).

FXL16_HUMAN
θ value	0.0563607 (rank : 36)	NC score	0.059924 (rank : 61)
Query Neighborhood Hits	78	Target Neighborhood Hits	85	Shared Neighborhood Hits	9
SwissProt Accessions	Q8N461, Q2MHR2, Q96S14, Q9UJI0	Gene names	FBXL16, C16orf22, FBL16
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 16 (F-box and leucine-rich repeat protein 16).

GP1BA_HUMAN
θ value	0.0736092 (rank : 37)	NC score	0.051822 (rank : 68)
Query Neighborhood Hits	78	Target Neighborhood Hits	407	Shared Neighborhood Hits	31
SwissProt Accessions	P07359, Q14441, Q16469, Q8N1F3, Q8NG39, Q9HDC7, Q9UEK1, Q9UQS4	Gene names	GP1BA
Domain Architecture
Description	Platelet glycoprotein Ib alpha chain precursor (Glycoprotein Ibalpha) (GP-Ib alpha) (GPIbA) (GPIb-alpha) (Antigen CD42b-alpha) (CD42b antigen) [Contains: Glycocalicin].

LRC47_HUMAN
θ value	0.0736092 (rank : 38)	NC score	0.055905 (rank : 62)
Query Neighborhood Hits	78	Target Neighborhood Hits	300	Shared Neighborhood Hits	33
SwissProt Accessions	Q8N1G4, Q9ULN5	Gene names	LRRC47, KIAA1185
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 47.

AN32D_HUMAN
θ value	0.125558 (rank : 39)	NC score	0.031947 (rank : 81)
Query Neighborhood Hits	78	Target Neighborhood Hits	95	Shared Neighborhood Hits	12
SwissProt Accessions	O95626, Q6NTC4	Gene names	ANP32D, PP32R2
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member D (Phosphoprotein 32-related protein 2) (Tumorigenic protein pp32r2).

LRC56_HUMAN
θ value	0.125558 (rank : 40)	NC score	0.043221 (rank : 71)
Query Neighborhood Hits	78	Target Neighborhood Hits	165	Shared Neighborhood Hits	13
SwissProt Accessions	Q8IYG6, Q8N3Q4	Gene names	LRRC56
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 56.

LRC41_MOUSE
θ value	0.21417 (rank : 41)	NC score	0.098796 (rank : 45)
Query Neighborhood Hits	78	Target Neighborhood Hits	37	Shared Neighborhood Hits	18
SwissProt Accessions	Q8K1C9, Q91VX4	Gene names	Lrrc41, Muf1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 41 (Protein Muf1).

PRAM7_HUMAN
θ value	0.21417 (rank : 42)	NC score	0.048472 (rank : 70)
Query Neighborhood Hits	78	Target Neighborhood Hits	28	Shared Neighborhood Hits	12
SwissProt Accessions	Q5VXH5	Gene names	PRAMEF7
Domain Architecture	No domain graphic available
Description	PRAME family member 7.

PRAM8_HUMAN
θ value	0.21417 (rank : 43)	NC score	0.049618 (rank : 69)
Query Neighborhood Hits	78	Target Neighborhood Hits	27	Shared Neighborhood Hits	12
SwissProt Accessions	Q5VWM4	Gene names	PRAMEF8
Domain Architecture	No domain graphic available
Description	PRAME family member 8.

LRC41_HUMAN
θ value	0.279714 (rank : 44)	NC score	0.094682 (rank : 47)
Query Neighborhood Hits	78	Target Neighborhood Hits	51	Shared Neighborhood Hits	17
SwissProt Accessions	Q15345, Q71RA8, Q9BSM0	Gene names	LRRC41, MUF1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 41 (Protein Muf1).

LRC47_MOUSE
θ value	0.279714 (rank : 45)	NC score	0.052260 (rank : 67)
Query Neighborhood Hits	78	Target Neighborhood Hits	299	Shared Neighborhood Hits	32
SwissProt Accessions	Q505F5, Q3U380, Q6ZPW2, Q9CUZ0	Gene names	Lrrc47, Kiaa1185
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 47.

GP125_HUMAN
θ value	0.365318 (rank : 46)	NC score	0.027262 (rank : 85)
Query Neighborhood Hits	78	Target Neighborhood Hits	327	Shared Neighborhood Hits	28
SwissProt Accessions	Q8IWK6, Q6UXK9, Q86SQ5, Q8TC55	Gene names	GPR125
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 125 precursor.

LRC15_HUMAN
θ value	0.365318 (rank : 47)	NC score	0.036479 (rank : 76)
Query Neighborhood Hits	78	Target Neighborhood Hits	305	Shared Neighborhood Hits	36
SwissProt Accessions	Q8TF66, Q7RTN7	Gene names	LRRC15, LIB
Domain Architecture
Description	Leucine-rich repeat-containing protein 15 precursor (hLib).

TMOD4_MOUSE
θ value	0.47712 (rank : 48)	NC score	0.086304 (rank : 51)
Query Neighborhood Hits	78	Target Neighborhood Hits	36	Shared Neighborhood Hits	20
SwissProt Accessions	Q9JLH8	Gene names	Tmod4
Domain Architecture
Description	Tropomodulin-4 (Skeletal muscle tropomodulin) (Sk-Tmod).

TMOD4_HUMAN
θ value	0.62314 (rank : 49)	NC score	0.090582 (rank : 49)
Query Neighborhood Hits	78	Target Neighborhood Hits	37	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NZQ9, Q8WVL3, Q9UKH2	Gene names	TMOD4
Domain Architecture
Description	Tropomodulin-4 (Skeletal muscle tropomodulin) (Sk-Tmod).

LRC57_HUMAN
θ value	0.813845 (rank : 50)	NC score	0.055549 (rank : 63)
Query Neighborhood Hits	78	Target Neighborhood Hits	271	Shared Neighborhood Hits	36
SwissProt Accessions	Q8N9N7, Q7Z2Z6, Q8N1T6	Gene names	LRRC57
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 57.

LRC24_HUMAN
θ value	1.06291 (rank : 51)	NC score	0.027329 (rank : 84)
Query Neighborhood Hits	78	Target Neighborhood Hits	404	Shared Neighborhood Hits	28
SwissProt Accessions	Q50LG9	Gene names	LRRC24
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 24 precursor.

LRCH4_MOUSE
θ value	1.06291 (rank : 52)	NC score	0.033898 (rank : 80)
Query Neighborhood Hits	78	Target Neighborhood Hits	302	Shared Neighborhood Hits	28
SwissProt Accessions	Q921G6	Gene names	Lrch4
Domain Architecture
Description	Leucine-rich repeats and calponin homology domain-containing protein 4.

PRA12_HUMAN
θ value	1.38821 (rank : 53)	NC score	0.055222 (rank : 64)
Query Neighborhood Hits	78	Target Neighborhood Hits	38	Shared Neighborhood Hits	14
SwissProt Accessions	O95522	Gene names
Domain Architecture	No domain graphic available
Description	PRAME family member DJ1198H6.2.

ECM2_HUMAN
θ value	1.81305 (rank : 54)	NC score	0.036296 (rank : 77)
Query Neighborhood Hits	78	Target Neighborhood Hits	402	Shared Neighborhood Hits	34
SwissProt Accessions	O94769	Gene names	ECM2
Domain Architecture
Description	Extracellular matrix protein 2 precursor (Matrix glycoprotein SC1/ECM2).

LGR4_HUMAN
θ value	2.36792 (rank : 55)	NC score	0.023674 (rank : 89)
Query Neighborhood Hits	78	Target Neighborhood Hits	481	Shared Neighborhood Hits	31
SwissProt Accessions	Q9BXB1, Q9NYD1	Gene names	LGR4, GPR48
Domain Architecture
Description	Leucine-rich repeat-containing G-protein coupled receptor 4 precursor (G-protein coupled receptor 48).

LRC40_MOUSE
θ value	2.36792 (rank : 56)	NC score	0.040356 (rank : 72)
Query Neighborhood Hits	78	Target Neighborhood Hits	311	Shared Neighborhood Hits	33
SwissProt Accessions	Q9CRC8, Q78WQ9, Q8BS83	Gene names	Lrrc40
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 40.

LRC57_MOUSE
θ value	2.36792 (rank : 57)	NC score	0.054005 (rank : 66)
Query Neighborhood Hits	78	Target Neighborhood Hits	267	Shared Neighborhood Hits	36
SwissProt Accessions	Q9D1G5, Q9DC95	Gene names	Lrrc57
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 57.

TMOD3_MOUSE
θ value	2.36792 (rank : 58)	NC score	0.088425 (rank : 50)
Query Neighborhood Hits	78	Target Neighborhood Hits	34	Shared Neighborhood Hits	22
SwissProt Accessions	Q9JHJ0, Q3TIT1	Gene names	Tmod3
Domain Architecture
Description	Tropomodulin-3 (Ubiquitous tropomodulin) (U-Tmod).

FLII_MOUSE
θ value	3.0926 (rank : 59)	NC score	0.039373 (rank : 75)
Query Neighborhood Hits	78	Target Neighborhood Hits	304	Shared Neighborhood Hits	34
SwissProt Accessions	Q9JJ28, Q8K095, Q8VI44	Gene names	Flii, Fli1, Fliih
Domain Architecture	No domain graphic available
Description	Protein flightless-1 homolog.

GP125_MOUSE
θ value	3.0926 (rank : 60)	NC score	0.025740 (rank : 86)
Query Neighborhood Hits	78	Target Neighborhood Hits	329	Shared Neighborhood Hits	27
SwissProt Accessions	Q7TT36, Q6PE67, Q8VE71	Gene names	Gpr125
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 125 precursor.

TMOD2_MOUSE
θ value	3.0926 (rank : 61)	NC score	0.080184 (rank : 54)
Query Neighborhood Hits	78	Target Neighborhood Hits	41	Shared Neighborhood Hits	19
SwissProt Accessions	Q9JKK7, Q9JLH9	Gene names	Tmod2
Domain Architecture
Description	Tropomodulin-2 (Neuronal tropomodulin) (N-Tmod).

FLII_HUMAN
θ value	4.03905 (rank : 62)	NC score	0.034958 (rank : 79)
Query Neighborhood Hits	78	Target Neighborhood Hits	318	Shared Neighborhood Hits	34
SwissProt Accessions	Q13045	Gene names	FLII, FLIL
Domain Architecture
Description	Protein flightless-1 homolog.

LRC24_MOUSE
θ value	4.03905 (rank : 63)	NC score	0.022324 (rank : 91)
Query Neighborhood Hits	78	Target Neighborhood Hits	387	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BHA1	Gene names	Lrrc24
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 24 precursor.

TLR9_HUMAN
θ value	4.03905 (rank : 64)	NC score	0.023799 (rank : 88)
Query Neighborhood Hits	78	Target Neighborhood Hits	295	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NR96, Q6UVZ2, Q9HD68, Q9HD69, Q9HD70, Q9NYC2, Q9NYC3	Gene names	TLR9
Domain Architecture
Description	Toll-like receptor 9 precursor (CD289 antigen).

TMOD1_MOUSE
θ value	4.03905 (rank : 65)	NC score	0.080339 (rank : 53)
Query Neighborhood Hits	78	Target Neighborhood Hits	28	Shared Neighborhood Hits	18
SwissProt Accessions	P49813, Q9ERR9	Gene names	Tmod1, Tmod
Domain Architecture
Description	Tropomodulin-1 (Erythrocyte tropomodulin) (E-Tmod).

AN32C_HUMAN
θ value	5.27518 (rank : 66)	NC score	0.022812 (rank : 90)
Query Neighborhood Hits	78	Target Neighborhood Hits	100	Shared Neighborhood Hits	9
SwissProt Accessions	O43423	Gene names	ANP32C, PP32R1
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member C (Phosphoprotein 32-related protein 1) (Tumorigenic protein pp32r1).

LRC33_HUMAN
θ value	5.27518 (rank : 67)	NC score	0.040062 (rank : 74)
Query Neighborhood Hits	78	Target Neighborhood Hits	293	Shared Neighborhood Hits	37
SwissProt Accessions	Q86YC3	Gene names	LRRC33
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 33 precursor.

OPT_HUMAN
θ value	5.27518 (rank : 68)	NC score	0.020216 (rank : 93)
Query Neighborhood Hits	78	Target Neighborhood Hits	255	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UBM4	Gene names	OPTC, OPT
Domain Architecture	No domain graphic available
Description	Opticin precursor (Oculoglycan).

TMOD1_HUMAN
θ value	5.27518 (rank : 69)	NC score	0.076424 (rank : 56)
Query Neighborhood Hits	78	Target Neighborhood Hits	32	Shared Neighborhood Hits	19
SwissProt Accessions	P28289, Q9BUF1	Gene names	TMOD1, TMOD
Domain Architecture
Description	Tropomodulin-1 (Erythrocyte tropomodulin) (E-Tmod).

ALS_MOUSE
θ value	6.88961 (rank : 70)	NC score	0.021027 (rank : 92)
Query Neighborhood Hits	78	Target Neighborhood Hits	275	Shared Neighborhood Hits	26
SwissProt Accessions	P70389, Q9DBI7	Gene names	Igfals, Albs, Als
Domain Architecture
Description	Insulin-like growth factor-binding protein complex acid labile chain precursor (ALS).

I17RA_HUMAN
θ value	6.88961 (rank : 71)	NC score	0.008747 (rank : 94)
Query Neighborhood Hits	78	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	Q96F46, O43844	Gene names	IL17RA, IL17R
Domain Architecture	No domain graphic available
Description	Interleukin-17 receptor A precursor (IL-17 receptor).

MAPE_HUMAN
θ value	6.88961 (rank : 72)	NC score	0.076552 (rank : 55)
Query Neighborhood Hits	78	Target Neighborhood Hits	24	Shared Neighborhood Hits	14
SwissProt Accessions	P78395, O43481, Q8IXN8	Gene names	PRAME, MAPE
Domain Architecture	No domain graphic available
Description	Melanoma antigen preferentially expressed in tumors (Preferentially expressed antigen of melanoma) (OPA-interacting protein 4) (OIP4).

PHLPP_HUMAN
θ value	6.88961 (rank : 73)	NC score	0.040264 (rank : 73)
Query Neighborhood Hits	78	Target Neighborhood Hits	604	Shared Neighborhood Hits	35
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

LGR5_HUMAN
θ value	8.99809 (rank : 74)	NC score	0.027804 (rank : 83)
Query Neighborhood Hits	78	Target Neighborhood Hits	452	Shared Neighborhood Hits	35
SwissProt Accessions	O75473, Q9UP75	Gene names	LGR5, GPR49, GPR67
Domain Architecture
Description	Leucine-rich repeat-containing G-protein coupled receptor 5 precursor (Orphan G-protein coupled receptor HG38) (G-protein coupled receptor 49) (G-protein coupled receptor 67).

LRC10_HUMAN
θ value	8.99809 (rank : 75)	NC score	0.025547 (rank : 87)
Query Neighborhood Hits	78	Target Neighborhood Hits	200	Shared Neighborhood Hits	22
SwissProt Accessions	Q5BKY1, Q6ZVY4	Gene names	LRRC10
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 10.

LRC14_HUMAN
θ value	8.99809 (rank : 76)	NC score	0.122448 (rank : 38)
Query Neighborhood Hits	78	Target Neighborhood Hits	57	Shared Neighborhood Hits	22
SwissProt Accessions	Q15048	Gene names	LRRC14, KIAA0014
Domain Architecture
Description	Leucine-rich repeat-containing protein 14.

TLR11_MOUSE
θ value	8.99809 (rank : 77)	NC score	0.030331 (rank : 82)
Query Neighborhood Hits	78	Target Neighborhood Hits	293	Shared Neighborhood Hits	32
SwissProt Accessions	Q6R5P0	Gene names	Tlr11
Domain Architecture	No domain graphic available
Description	Toll-like receptor 11 precursor.

TMOD2_HUMAN
θ value	8.99809 (rank : 78)	NC score	0.091841 (rank : 48)
Query Neighborhood Hits	78	Target Neighborhood Hits	29	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NZR1	Gene names	TMOD2, NTMOD
Domain Architecture
Description	Tropomodulin-2 (Neuronal tropomodulin) (N-Tmod).

ASC_HUMAN
θ value	θ > 10 (rank : 79)	NC score	0.141958 (rank : 35)
Query Neighborhood Hits	78	Target Neighborhood Hits	18	Shared Neighborhood Hits	8
SwissProt Accessions	Q9ULZ3, Q96D12, Q9BSZ5, Q9HBD0, Q9NXJ8	Gene names	PYCARD, ASC, CARD5, TMS1
Domain Architecture
Description	Apoptosis-associated speck-like protein containing a CARD (hASC) (PYD and CARD domain-containing protein) (Target of methylation-induced silencing 1) (Caspase recruitment domain-containing protein 5).

ASC_MOUSE
θ value	θ > 10 (rank : 80)	NC score	0.180111 (rank : 34)
Query Neighborhood Hits	78	Target Neighborhood Hits	17	Shared Neighborhood Hits	9
SwissProt Accessions	Q9EPB4, Q9D2W9	Gene names	Pycard, Asc
Domain Architecture
Description	Apoptosis-associated speck-like protein containing a CARD (mASC) (PYD and CARD domain-containing protein).

BIR1A_MOUSE
θ value	θ > 10 (rank : 81)	NC score	0.125545 (rank : 37)
Query Neighborhood Hits	78	Target Neighborhood Hits	94	Shared Neighborhood Hits	23
SwissProt Accessions	Q9QWK5, Q9JIB5, Q9R017	Gene names	Birc1a, Naip, Naip1
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1a (Neuronal apoptosis inhibitory protein 1).

BIR1B_MOUSE
θ value	θ > 10 (rank : 82)	NC score	0.111407 (rank : 42)
Query Neighborhood Hits	78	Target Neighborhood Hits	93	Shared Neighborhood Hits	25
SwissProt Accessions	Q9QUK4, O09124, Q9R030	Gene names	Birc1b, Naip-rs6, Naip2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1b (Neuronal apoptosis inhibitory protein 2).

BIR1E_MOUSE
θ value	θ > 10 (rank : 83)	NC score	0.121345 (rank : 39)
Query Neighborhood Hits	78	Target Neighborhood Hits	93	Shared Neighborhood Hits	25
SwissProt Accessions	Q9R016, O09121, O09122, P81703, Q9R029	Gene names	Birc1e, Naip-rs3, Naip5
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1e (Neuronal apoptosis inhibitory protein 5).

BIR1F_MOUSE
θ value	θ > 10 (rank : 84)	NC score	0.121062 (rank : 40)
Query Neighborhood Hits	78	Target Neighborhood Hits	88	Shared Neighborhood Hits	25
SwissProt Accessions	Q9JIB6, O09121, O09122, P81704	Gene names	Birc1f, Naip-rs4, Naip6
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1f (Neuronal apoptosis inhibitory protein 6).

BIR1G_MOUSE
θ value	θ > 10 (rank : 85)	NC score	0.114745 (rank : 41)
Query Neighborhood Hits	78	Target Neighborhood Hits	92	Shared Neighborhood Hits	24
SwissProt Accessions	Q9JIB3	Gene names	Birc1g, Naip7
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1g (Neuronal apoptosis inhibitory protein 7).

BIRC1_HUMAN
θ value	θ > 10 (rank : 86)	NC score	0.140639 (rank : 36)
Query Neighborhood Hits	78	Target Neighborhood Hits	61	Shared Neighborhood Hits	21
SwissProt Accessions	Q13075, O75857, Q13730, Q99796	Gene names	BIRC1, NAIP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1 (Neuronal apoptosis inhibitory protein).

CARD8_HUMAN
θ value	θ > 10 (rank : 87)	NC score	0.107178 (rank : 43)
Query Neighborhood Hits	78	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y2G2, Q6PGP8, Q96P82	Gene names	CARD8, KIAA0955, NDPP1
Domain Architecture
Description	Caspase recruitment domain-containing protein 8 (Apoptotic protein NDPP1) (DACAR) (CARD-inhibitor of NF-kappa-B-activating ligand) (CARDINAL) (Tumor-up-regulated CARD-containing antagonist of CASP9) (TUCAN).

CD14_MOUSE
θ value	θ > 10 (rank : 88)	NC score	0.070574 (rank : 58)
Query Neighborhood Hits	78	Target Neighborhood Hits	104	Shared Neighborhood Hits	20
SwissProt Accessions	P10810	Gene names	Cd14
Domain Architecture
Description	Monocyte differentiation antigen CD14 precursor (Myeloid cell-specific leucine-rich glycoprotein).

LMD1_HUMAN
θ value	θ > 10 (rank : 89)	NC score	0.068019 (rank : 59)
Query Neighborhood Hits	78	Target Neighborhood Hits	169	Shared Neighborhood Hits	16
SwissProt Accessions	P29536	Gene names	LMOD1
Domain Architecture
Description	Leiomodin-1 (Leiomodin, muscle form) (64 kDa autoantigen D1) (64 kDa autoantigen 1D) (64 kDa autoantigen 1D3) (Thyroid-associated ophthalmopathy autoantigen) (Smooth muscle leiomodin) (SM-Lmod).

MEFV_HUMAN
θ value	θ > 10 (rank : 90)	NC score	0.054709 (rank : 65)
Query Neighborhood Hits	78	Target Neighborhood Hits	431	Shared Neighborhood Hits	9
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

MEFV_MOUSE
θ value	θ > 10 (rank : 91)	NC score	0.098195 (rank : 46)
Query Neighborhood Hits	78	Target Neighborhood Hits	236	Shared Neighborhood Hits	9
SwissProt Accessions	Q9JJ26	Gene names	Mefv
Domain Architecture
Description	Pyrin (Marenostrin).

NAL10_HUMAN
θ value	θ > 10 (rank : 92)	NC score	0.657515 (rank : 21)
Query Neighborhood Hits	78	Target Neighborhood Hits	55	Shared Neighborhood Hits	21
SwissProt Accessions	Q86W26, Q6JGT0	Gene names	NALP10, NOD8, PYNOD
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 10 (Nucleotide-binding oligomerization domain protein 8).

NAL10_MOUSE
θ value	θ > 10 (rank : 93)	NC score	0.649598 (rank : 22)
Query Neighborhood Hits	78	Target Neighborhood Hits	46	Shared Neighborhood Hits	21
SwissProt Accessions	Q8CCN1	Gene names	Nalp10, Pynod
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 10.

TMOD3_HUMAN
θ value	θ > 10 (rank : 94)	NC score	0.073553 (rank : 57)
Query Neighborhood Hits	78	Target Neighborhood Hits	35	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NYL9, Q9NT43, Q9NZR0	Gene names	TMOD3
Domain Architecture
Description	Tropomodulin-3 (Ubiquitous tropomodulin) (U-Tmod).

Hits sorted by NC score

RINI_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	78	Target Neighborhood Hits	78	Shared Neighborhood Hits	78
SwissProt Accessions	P13489	Gene names	RNH1, PRI, RNH
Domain Architecture
Description	Ribonuclease inhibitor (Ribonuclease/angiogenin inhibitor 1) (RAI) (Placental ribonuclease inhibitor) (RNase inhibitor) (RI).

RINI_MOUSE
NC score	0.983557 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	78	Target Neighborhood Hits	87	Shared Neighborhood Hits	49
SwissProt Accessions	Q91VI7, Q924P4	Gene names	Rnh1, Rnh
Domain Architecture	No domain graphic available
Description	Ribonuclease inhibitor (Ribonuclease/angiogenin inhibitor 1).

NALP5_HUMAN
NC score	0.902444 (rank : 3)	θ value	8.55514e-59 (rank : 4)
Query Neighborhood Hits	78	Target Neighborhood Hits	88	Shared Neighborhood Hits	40
SwissProt Accessions	P59047, Q86W29	Gene names	NALP5, MATER
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Mater protein homolog).

NAL14_HUMAN
NC score	0.892489 (rank : 4)	θ value	8.85319e-56 (rank : 6)
Query Neighborhood Hits	78	Target Neighborhood Hits	76	Shared Neighborhood Hits	37
SwissProt Accessions	Q86W24, Q7RTR6	Gene names	NALP14, NOD5
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 14 (Nucleotide-binding oligomerization domain protein 5).

NAL12_HUMAN
NC score	0.886462 (rank : 5)	θ value	5.51964e-74 (rank : 3)
Query Neighborhood Hits	78	Target Neighborhood Hits	96	Shared Neighborhood Hits	43
SwissProt Accessions	P59046, Q8NEU4, Q9BY26	Gene names	NALP12, PYPAF7, RNO
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 12 (PYRIN-containing APAF1-like protein 7) (Monarch-1) (Regulated by nitric oxide).

NAL11_HUMAN
NC score	0.885689 (rank : 6)	θ value	3.04986e-48 (rank : 8)
Query Neighborhood Hits	78	Target Neighborhood Hits	66	Shared Neighborhood Hits	38
SwissProt Accessions	P59045, Q53ZZ0, Q8NBF5	Gene names	NALP11, NOD17, PYPAF6
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 11 (PYRIN-containing APAF1-like protein 6) (Nucleotide-binding oligomerization domain protein 17).

NAL13_HUMAN
NC score	0.884687 (rank : 7)	θ value	1.32601e-43 (rank : 11)
Query Neighborhood Hits	78	Target Neighborhood Hits	93	Shared Neighborhood Hits	34
SwissProt Accessions	Q86W25, Q7RTR5	Gene names	NALP13, NOD14
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 13 (Nucleotide-binding oligomerization domain protein 14).

CIAS1_MOUSE
NC score	0.878050 (rank : 8)	θ value	1.78386e-56 (rank : 5)
Query Neighborhood Hits	78	Target Neighborhood Hits	67	Shared Neighborhood Hits	35
SwissProt Accessions	Q8R4B8, Q6JEL0	Gene names	Cias1, Mmig1, Nalp3, Pypaf1
Domain Architecture
Description	Cold autoinflammatory syndrome 1 protein homolog (PYRIN-containing APAF1-like protein 1) (Mast cell maturation-associated-inducible protein 1) (Cryopyrin).

NALP4_HUMAN
NC score	0.876642 (rank : 9)	θ value	6.58091e-43 (rank : 12)
Query Neighborhood Hits	78	Target Neighborhood Hits	81	Shared Neighborhood Hits	37
SwissProt Accessions	Q96MN2, Q86W87, Q96AY6	Gene names	NALP4, PAN2, PYPAF4, RNH2
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 4 (PYRIN-containing APAF1-like protein 4) (PAAD and NACHT-containing protein 2) (PYRIN and NACHT- containing protein 2) (Ribonuclease inhibitor 2).

NALP2_HUMAN
NC score	0.874853 (rank : 10)	θ value	9.18288e-45 (rank : 10)
Query Neighborhood Hits	78	Target Neighborhood Hits	65	Shared Neighborhood Hits	35
SwissProt Accessions	Q9NX02, Q53FL5, Q59G09, Q8IXT0, Q9BVN5, Q9H6G6, Q9HAV9, Q9NWK3	Gene names	NALP2, NBS1, PAN1, PYPAF2
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 2 (PYRIN domain and NACHT domain-containing protein 1) (PYRIN-containing APAF1-like protein 2) (Nucleotide-binding site protein 1).

CIAS1_HUMAN
NC score	0.872956 (rank : 11)	θ value	6.34462e-54 (rank : 7)
Query Neighborhood Hits	78	Target Neighborhood Hits	76	Shared Neighborhood Hits	36
SwissProt Accessions	Q96P20, O75434, Q59H68, Q5JQS8, Q5JQS9, Q6TG35, Q8TCW0, Q8TEU9, Q8WXH9	Gene names	CIAS1, NALP3, PYPAF1
Domain Architecture
Description	Cold autoinflammatory syndrome 1 protein (Cryopyrin) (NACHT-, LRR- and PYD-containing protein 3) (PYRIN-containing APAF1-like protein 1) (Angiotensin/vasopressin receptor AII/AVP-like).

NALP7_HUMAN
NC score	0.843461 (rank : 12)	θ value	1.92365e-26 (rank : 14)
Query Neighborhood Hits	78	Target Neighborhood Hits	65	Shared Neighborhood Hits	28
SwissProt Accessions	Q8WX94, Q7RTR1	Gene names	NALP7, NOD12, PYPAF3
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 7 (PYRIN-containing APAF1-like protein 3).

NALP5_MOUSE
NC score	0.835630 (rank : 13)	θ value	2.85459e-46 (rank : 9)
Query Neighborhood Hits	78	Target Neighborhood Hits	560	Shared Neighborhood Hits	40
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

NALP1_HUMAN
NC score	0.816649 (rank : 14)	θ value	2.12192e-33 (rank : 13)
Query Neighborhood Hits	78	Target Neighborhood Hits	138	Shared Neighborhood Hits	40
SwissProt Accessions	Q9C000, Q9BZZ8, Q9BZZ9, Q9HAV8, Q9UFT4, Q9Y2E0	Gene names	NALP1, CARD7, DEFCAP, KIAA0926, NAC
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 1 (Death effector filament- forming ced-4-like apoptosis protein) (Nucleotide-binding domain and caspase recruitment domain) (Caspase recruitment domain protein 7).

NALP6_MOUSE
NC score	0.779237 (rank : 15)	θ value	2.13179e-17 (rank : 16)
Query Neighborhood Hits	78	Target Neighborhood Hits	55	Shared Neighborhood Hits	28
SwissProt Accessions	Q91WS2, Q8K0L4	Gene names	Nalp6, Pypaf5
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 6 (PYRIN-containing APAF1-like protein 5-like).

NALP6_HUMAN
NC score	0.774969 (rank : 16)	θ value	1.16975e-15 (rank : 18)
Query Neighborhood Hits	78	Target Neighborhood Hits	52	Shared Neighborhood Hits	26
SwissProt Accessions	P59044	Gene names	NALP6, PYPAF5
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 6 (PYRIN-containing APAF1-like protein 5).

CAR15_MOUSE
NC score	0.708307 (rank : 17)	θ value	1.99529e-15 (rank : 20)
Query Neighborhood Hits	78	Target Neighborhood Hits	93	Shared Neighborhood Hits	46
SwissProt Accessions	Q8K3Z0	Gene names	Card15, Nod2
Domain Architecture
Description	Caspase recruitment domain-containing protein 15 (Protein Nod2).

CARD4_HUMAN
NC score	0.706501 (rank : 18)	θ value	3.63628e-17 (rank : 17)
Query Neighborhood Hits	78	Target Neighborhood Hits	102	Shared Neighborhood Hits	46
SwissProt Accessions	Q9Y239, Q8IWF5	Gene names	CARD4, NOD1
Domain Architecture
Description	Caspase recruitment domain-containing protein 4 (Protein Nod1).

CAR15_HUMAN
NC score	0.701214 (rank : 19)	θ value	5.8054e-15 (rank : 21)
Query Neighborhood Hits	78	Target Neighborhood Hits	77	Shared Neighborhood Hits	43
SwissProt Accessions	Q9HC29, Q96RH5, Q96RH6, Q96RH8	Gene names	CARD15, IBD1, NOD2
Domain Architecture
Description	Caspase recruitment domain-containing protein 15 (Protein Nod2) (Inflammatory bowel disease protein 1).

CARD4_MOUSE
NC score	0.699647 (rank : 20)	θ value	1.52774e-15 (rank : 19)
Query Neighborhood Hits	78	Target Neighborhood Hits	85	Shared Neighborhood Hits	41
SwissProt Accessions	Q8BHB0, Q8BUT6	Gene names	Card4
Domain Architecture
Description	Caspase recruitment domain-containing protein 4.

NAL10_HUMAN
NC score	0.657515 (rank : 21)	θ value	θ > 10 (rank : 92)
Query Neighborhood Hits	78	Target Neighborhood Hits	55	Shared Neighborhood Hits	21
SwissProt Accessions	Q86W26, Q6JGT0	Gene names	NALP10, NOD8, PYNOD
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 10 (Nucleotide-binding oligomerization domain protein 8).

NAL10_MOUSE
NC score	0.649598 (rank : 22)	θ value	θ > 10 (rank : 93)
Query Neighborhood Hits	78	Target Neighborhood Hits	46	Shared Neighborhood Hits	21
SwissProt Accessions	Q8CCN1	Gene names	Nalp10, Pynod
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 10.

LRC31_HUMAN
NC score	0.624865 (rank : 23)	θ value	5.99374e-20 (rank : 15)
Query Neighborhood Hits	78	Target Neighborhood Hits	139	Shared Neighborhood Hits	41
SwissProt Accessions	Q6UY01, Q8N848, Q9H5N5	Gene names	LRRC31
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 31.

LRC34_HUMAN
NC score	0.618621 (rank : 24)	θ value	6.43352e-06 (rank : 26)
Query Neighborhood Hits	78	Target Neighborhood Hits	67	Shared Neighborhood Hits	39
SwissProt Accessions	Q8IZ02	Gene names	LRRC34
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 34.

CF154_HUMAN
NC score	0.615202 (rank : 25)	θ value	2.79066e-09 (rank : 22)
Query Neighborhood Hits	78	Target Neighborhood Hits	36	Shared Neighborhood Hits	29
SwissProt Accessions	Q5JTD7	Gene names	C6orf154
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf154.

LRC34_MOUSE
NC score	0.593435 (rank : 26)	θ value	1.06045e-08 (rank : 23)
Query Neighborhood Hits	78	Target Neighborhood Hits	58	Shared Neighborhood Hits	38
SwissProt Accessions	Q9DAM1	Gene names	Lrrc34
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 34.

C2TA_MOUSE
NC score	0.534582 (rank : 27)	θ value	0.00020696 (rank : 30)
Query Neighborhood Hits	78	Target Neighborhood Hits	131	Shared Neighborhood Hits	45
SwissProt Accessions	P79621, O46787, O78036, O78109, Q31115, Q9TPP1	Gene names	Ciita, C2ta, Mhc2ta
Domain Architecture
Description	MHC class II transactivator (CIITA).

C2TA_HUMAN
NC score	0.519191 (rank : 28)	θ value	0.00298849 (rank : 31)
Query Neighborhood Hits	78	Target Neighborhood Hits	190	Shared Neighborhood Hits	37
SwissProt Accessions	P33076	Gene names	CIITA, MHC2TA
Domain Architecture
Description	MHC class II transactivator (CIITA).

RGP1_HUMAN
NC score	0.443924 (rank : 29)	θ value	2.88788e-06 (rank : 25)
Query Neighborhood Hits	78	Target Neighborhood Hits	124	Shared Neighborhood Hits	26
SwissProt Accessions	P46060	Gene names	RANGAP1
Domain Architecture
Description	Ran GTPase-activating protein 1.

RGP1_MOUSE
NC score	0.425153 (rank : 30)	θ value	1.87187e-05 (rank : 28)
Query Neighborhood Hits	78	Target Neighborhood Hits	105	Shared Neighborhood Hits	27
SwissProt Accessions	P46061, Q60801	Gene names	Rangap1, Fug1
Domain Architecture
Description	Ran GTPase-activating protein 1.

CAR12_HUMAN
NC score	0.297515 (rank : 31)	θ value	4.1701e-05 (rank : 29)
Query Neighborhood Hits	78	Target Neighborhood Hits	132	Shared Neighborhood Hits	39
SwissProt Accessions	Q9NPP4, Q96J81, Q96J82, Q96J83	Gene names	CARD12, CLAN, CLAN1
Domain Architecture
Description	Caspase recruitment domain-containing protein 12 (Ice protease- activating factor) (Ipaf) (CARD, LRR, and NACHT-containing protein) (Clan protein).

LRC45_MOUSE
NC score	0.221869 (rank : 32)	θ value	1.17247e-07 (rank : 24)
Query Neighborhood Hits	78	Target Neighborhood Hits	959	Shared Neighborhood Hits	45
SwissProt Accessions	Q8CIM1, Q3U5Z2	Gene names	Lrrc45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

LRC45_HUMAN
NC score	0.210018 (rank : 33)	θ value	6.43352e-06 (rank : 27)
Query Neighborhood Hits	78	Target Neighborhood Hits	933	Shared Neighborhood Hits	38
SwissProt Accessions	Q96CN5	Gene names	LRRC45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

ASC_MOUSE
NC score	0.180111 (rank : 34)	θ value	θ > 10 (rank : 80)
Query Neighborhood Hits	78	Target Neighborhood Hits	17	Shared Neighborhood Hits	9
SwissProt Accessions	Q9EPB4, Q9D2W9	Gene names	Pycard, Asc
Domain Architecture
Description	Apoptosis-associated speck-like protein containing a CARD (mASC) (PYD and CARD domain-containing protein).

ASC_HUMAN
NC score	0.141958 (rank : 35)	θ value	θ > 10 (rank : 79)
Query Neighborhood Hits	78	Target Neighborhood Hits	18	Shared Neighborhood Hits	8
SwissProt Accessions	Q9ULZ3, Q96D12, Q9BSZ5, Q9HBD0, Q9NXJ8	Gene names	PYCARD, ASC, CARD5, TMS1
Domain Architecture
Description	Apoptosis-associated speck-like protein containing a CARD (hASC) (PYD and CARD domain-containing protein) (Target of methylation-induced silencing 1) (Caspase recruitment domain-containing protein 5).

BIRC1_HUMAN
NC score	0.140639 (rank : 36)	θ value	θ > 10 (rank : 86)
Query Neighborhood Hits	78	Target Neighborhood Hits	61	Shared Neighborhood Hits	21
SwissProt Accessions	Q13075, O75857, Q13730, Q99796	Gene names	BIRC1, NAIP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1 (Neuronal apoptosis inhibitory protein).

BIR1A_MOUSE
NC score	0.125545 (rank : 37)	θ value	θ > 10 (rank : 81)
Query Neighborhood Hits	78	Target Neighborhood Hits	94	Shared Neighborhood Hits	23
SwissProt Accessions	Q9QWK5, Q9JIB5, Q9R017	Gene names	Birc1a, Naip, Naip1
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1a (Neuronal apoptosis inhibitory protein 1).

LRC14_HUMAN
NC score	0.122448 (rank : 38)	θ value	8.99809 (rank : 76)
Query Neighborhood Hits	78	Target Neighborhood Hits	57	Shared Neighborhood Hits	22
SwissProt Accessions	Q15048	Gene names	LRRC14, KIAA0014
Domain Architecture
Description	Leucine-rich repeat-containing protein 14.

BIR1E_MOUSE
NC score	0.121345 (rank : 39)	θ value	θ > 10 (rank : 83)
Query Neighborhood Hits	78	Target Neighborhood Hits	93	Shared Neighborhood Hits	25
SwissProt Accessions	Q9R016, O09121, O09122, P81703, Q9R029	Gene names	Birc1e, Naip-rs3, Naip5
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1e (Neuronal apoptosis inhibitory protein 5).

BIR1F_MOUSE
NC score	0.121062 (rank : 40)	θ value	θ > 10 (rank : 84)
Query Neighborhood Hits	78	Target Neighborhood Hits	88	Shared Neighborhood Hits	25
SwissProt Accessions	Q9JIB6, O09121, O09122, P81704	Gene names	Birc1f, Naip-rs4, Naip6
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1f (Neuronal apoptosis inhibitory protein 6).

BIR1G_MOUSE
NC score	0.114745 (rank : 41)	θ value	θ > 10 (rank : 85)
Query Neighborhood Hits	78	Target Neighborhood Hits	92	Shared Neighborhood Hits	24
SwissProt Accessions	Q9JIB3	Gene names	Birc1g, Naip7
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1g (Neuronal apoptosis inhibitory protein 7).

BIR1B_MOUSE
NC score	0.111407 (rank : 42)	θ value	θ > 10 (rank : 82)
Query Neighborhood Hits	78	Target Neighborhood Hits	93	Shared Neighborhood Hits	25
SwissProt Accessions	Q9QUK4, O09124, Q9R030	Gene names	Birc1b, Naip-rs6, Naip2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1b (Neuronal apoptosis inhibitory protein 2).

CARD8_HUMAN
NC score	0.107178 (rank : 43)	θ value	θ > 10 (rank : 87)
Query Neighborhood Hits	78	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y2G2, Q6PGP8, Q96P82	Gene names	CARD8, KIAA0955, NDPP1
Domain Architecture
Description	Caspase recruitment domain-containing protein 8 (Apoptotic protein NDPP1) (DACAR) (CARD-inhibitor of NF-kappa-B-activating ligand) (CARDINAL) (Tumor-up-regulated CARD-containing antagonist of CASP9) (TUCAN).

LRC42_MOUSE
NC score	0.104141 (rank : 44)	θ value	0.00665767 (rank : 32)
Query Neighborhood Hits	78	Target Neighborhood Hits	25	Shared Neighborhood Hits	8
SwissProt Accessions	Q8R2U7, Q3TE62, Q9CTP9	Gene names	Lrrc42
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 42.

LRC41_MOUSE
NC score	0.098796 (rank : 45)	θ value	0.21417 (rank : 41)
Query Neighborhood Hits	78	Target Neighborhood Hits	37	Shared Neighborhood Hits	18
SwissProt Accessions	Q8K1C9, Q91VX4	Gene names	Lrrc41, Muf1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 41 (Protein Muf1).

MEFV_MOUSE
NC score	0.098195 (rank : 46)	θ value	θ > 10 (rank : 91)
Query Neighborhood Hits	78	Target Neighborhood Hits	236	Shared Neighborhood Hits	9
SwissProt Accessions	Q9JJ26	Gene names	Mefv
Domain Architecture
Description	Pyrin (Marenostrin).

LRC41_HUMAN
NC score	0.094682 (rank : 47)	θ value	0.279714 (rank : 44)
Query Neighborhood Hits	78	Target Neighborhood Hits	51	Shared Neighborhood Hits	17
SwissProt Accessions	Q15345, Q71RA8, Q9BSM0	Gene names	LRRC41, MUF1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 41 (Protein Muf1).

TMOD2_HUMAN
NC score	0.091841 (rank : 48)	θ value	8.99809 (rank : 78)
Query Neighborhood Hits	78	Target Neighborhood Hits	29	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NZR1	Gene names	TMOD2, NTMOD
Domain Architecture
Description	Tropomodulin-2 (Neuronal tropomodulin) (N-Tmod).

TMOD4_HUMAN
NC score	0.090582 (rank : 49)	θ value	0.62314 (rank : 49)
Query Neighborhood Hits	78	Target Neighborhood Hits	37	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NZQ9, Q8WVL3, Q9UKH2	Gene names	TMOD4
Domain Architecture
Description	Tropomodulin-4 (Skeletal muscle tropomodulin) (Sk-Tmod).

TMOD3_MOUSE
NC score	0.088425 (rank : 50)	θ value	2.36792 (rank : 58)
Query Neighborhood Hits	78	Target Neighborhood Hits	34	Shared Neighborhood Hits	22
SwissProt Accessions	Q9JHJ0, Q3TIT1	Gene names	Tmod3
Domain Architecture
Description	Tropomodulin-3 (Ubiquitous tropomodulin) (U-Tmod).

TMOD4_MOUSE
NC score	0.086304 (rank : 51)	θ value	0.47712 (rank : 48)
Query Neighborhood Hits	78	Target Neighborhood Hits	36	Shared Neighborhood Hits	20
SwissProt Accessions	Q9JLH8	Gene names	Tmod4
Domain Architecture
Description	Tropomodulin-4 (Skeletal muscle tropomodulin) (Sk-Tmod).

LRC42_HUMAN
NC score	0.084149 (rank : 52)	θ value	0.0330416 (rank : 34)
Query Neighborhood Hits	78	Target Neighborhood Hits	26	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y546, Q8N2Q8	Gene names	LRRC42
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 42.

TMOD1_MOUSE
NC score	0.080339 (rank : 53)	θ value	4.03905 (rank : 65)
Query Neighborhood Hits	78	Target Neighborhood Hits	28	Shared Neighborhood Hits	18
SwissProt Accessions	P49813, Q9ERR9	Gene names	Tmod1, Tmod
Domain Architecture
Description	Tropomodulin-1 (Erythrocyte tropomodulin) (E-Tmod).

TMOD2_MOUSE
NC score	0.080184 (rank : 54)	θ value	3.0926 (rank : 61)
Query Neighborhood Hits	78	Target Neighborhood Hits	41	Shared Neighborhood Hits	19
SwissProt Accessions	Q9JKK7, Q9JLH9	Gene names	Tmod2
Domain Architecture
Description	Tropomodulin-2 (Neuronal tropomodulin) (N-Tmod).

MAPE_HUMAN
NC score	0.076552 (rank : 55)	θ value	6.88961 (rank : 72)
Query Neighborhood Hits	78	Target Neighborhood Hits	24	Shared Neighborhood Hits	14
SwissProt Accessions	P78395, O43481, Q8IXN8	Gene names	PRAME, MAPE
Domain Architecture	No domain graphic available
Description	Melanoma antigen preferentially expressed in tumors (Preferentially expressed antigen of melanoma) (OPA-interacting protein 4) (OIP4).

TMOD1_HUMAN
NC score	0.076424 (rank : 56)	θ value	5.27518 (rank : 69)
Query Neighborhood Hits	78	Target Neighborhood Hits	32	Shared Neighborhood Hits	19
SwissProt Accessions	P28289, Q9BUF1	Gene names	TMOD1, TMOD
Domain Architecture
Description	Tropomodulin-1 (Erythrocyte tropomodulin) (E-Tmod).

TMOD3_HUMAN
NC score	0.073553 (rank : 57)	θ value	θ > 10 (rank : 94)
Query Neighborhood Hits	78	Target Neighborhood Hits	35	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NYL9, Q9NT43, Q9NZR0	Gene names	TMOD3
Domain Architecture
Description	Tropomodulin-3 (Ubiquitous tropomodulin) (U-Tmod).

CD14_MOUSE
NC score	0.070574 (rank : 58)	θ value	θ > 10 (rank : 88)
Query Neighborhood Hits	78	Target Neighborhood Hits	104	Shared Neighborhood Hits	20
SwissProt Accessions	P10810	Gene names	Cd14
Domain Architecture
Description	Monocyte differentiation antigen CD14 precursor (Myeloid cell-specific leucine-rich glycoprotein).

LMD1_HUMAN
NC score	0.068019 (rank : 59)	θ value	θ > 10 (rank : 89)
Query Neighborhood Hits	78	Target Neighborhood Hits	169	Shared Neighborhood Hits	16
SwissProt Accessions	P29536	Gene names	LMOD1
Domain Architecture
Description	Leiomodin-1 (Leiomodin, muscle form) (64 kDa autoantigen D1) (64 kDa autoantigen 1D) (64 kDa autoantigen 1D3) (Thyroid-associated ophthalmopathy autoantigen) (Smooth muscle leiomodin) (SM-Lmod).

TBCEL_HUMAN
NC score	0.065972 (rank : 60)	θ value	0.0431538 (rank : 35)
Query Neighborhood Hits	78	Target Neighborhood Hits	89	Shared Neighborhood Hits	11
SwissProt Accessions	Q5QJ74	Gene names	LRRC35
Domain Architecture	No domain graphic available
Description	Tubulin-specific chaperone cofactor E-like protein (Leucine-rich repeat-containing protein 35).

FXL16_HUMAN
NC score	0.059924 (rank : 61)	θ value	0.0563607 (rank : 36)
Query Neighborhood Hits	78	Target Neighborhood Hits	85	Shared Neighborhood Hits	9
SwissProt Accessions	Q8N461, Q2MHR2, Q96S14, Q9UJI0	Gene names	FBXL16, C16orf22, FBL16
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 16 (F-box and leucine-rich repeat protein 16).

LRC47_HUMAN
NC score	0.055905 (rank : 62)	θ value	0.0736092 (rank : 38)
Query Neighborhood Hits	78	Target Neighborhood Hits	300	Shared Neighborhood Hits	33
SwissProt Accessions	Q8N1G4, Q9ULN5	Gene names	LRRC47, KIAA1185
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 47.

LRC57_HUMAN
NC score	0.055549 (rank : 63)	θ value	0.813845 (rank : 50)
Query Neighborhood Hits	78	Target Neighborhood Hits	271	Shared Neighborhood Hits	36
SwissProt Accessions	Q8N9N7, Q7Z2Z6, Q8N1T6	Gene names	LRRC57
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 57.

PRA12_HUMAN
NC score	0.055222 (rank : 64)	θ value	1.38821 (rank : 53)
Query Neighborhood Hits	78	Target Neighborhood Hits	38	Shared Neighborhood Hits	14
SwissProt Accessions	O95522	Gene names
Domain Architecture	No domain graphic available
Description	PRAME family member DJ1198H6.2.

MEFV_HUMAN
NC score	0.054709 (rank : 65)	θ value	θ > 10 (rank : 90)
Query Neighborhood Hits	78	Target Neighborhood Hits	431	Shared Neighborhood Hits	9
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

LRC57_MOUSE
NC score	0.054005 (rank : 66)	θ value	2.36792 (rank : 57)
Query Neighborhood Hits	78	Target Neighborhood Hits	267	Shared Neighborhood Hits	36
SwissProt Accessions	Q9D1G5, Q9DC95	Gene names	Lrrc57
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 57.

LRC47_MOUSE
NC score	0.052260 (rank : 67)	θ value	0.279714 (rank : 45)
Query Neighborhood Hits	78	Target Neighborhood Hits	299	Shared Neighborhood Hits	32
SwissProt Accessions	Q505F5, Q3U380, Q6ZPW2, Q9CUZ0	Gene names	Lrrc47, Kiaa1185
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 47.

GP1BA_HUMAN
NC score	0.051822 (rank : 68)	θ value	0.0736092 (rank : 37)
Query Neighborhood Hits	78	Target Neighborhood Hits	407	Shared Neighborhood Hits	31
SwissProt Accessions	P07359, Q14441, Q16469, Q8N1F3, Q8NG39, Q9HDC7, Q9UEK1, Q9UQS4	Gene names	GP1BA
Domain Architecture
Description	Platelet glycoprotein Ib alpha chain precursor (Glycoprotein Ibalpha) (GP-Ib alpha) (GPIbA) (GPIb-alpha) (Antigen CD42b-alpha) (CD42b antigen) [Contains: Glycocalicin].

PRAM8_HUMAN
NC score	0.049618 (rank : 69)	θ value	0.21417 (rank : 43)
Query Neighborhood Hits	78	Target Neighborhood Hits	27	Shared Neighborhood Hits	12
SwissProt Accessions	Q5VWM4	Gene names	PRAMEF8
Domain Architecture	No domain graphic available
Description	PRAME family member 8.

PRAM7_HUMAN
NC score	0.048472 (rank : 70)	θ value	0.21417 (rank : 42)
Query Neighborhood Hits	78	Target Neighborhood Hits	28	Shared Neighborhood Hits	12
SwissProt Accessions	Q5VXH5	Gene names	PRAMEF7
Domain Architecture	No domain graphic available
Description	PRAME family member 7.

LRC56_HUMAN
NC score	0.043221 (rank : 71)	θ value	0.125558 (rank : 40)
Query Neighborhood Hits	78	Target Neighborhood Hits	165	Shared Neighborhood Hits	13
SwissProt Accessions	Q8IYG6, Q8N3Q4	Gene names	LRRC56
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 56.

LRC40_MOUSE
NC score	0.040356 (rank : 72)	θ value	2.36792 (rank : 56)
Query Neighborhood Hits	78	Target Neighborhood Hits	311	Shared Neighborhood Hits	33
SwissProt Accessions	Q9CRC8, Q78WQ9, Q8BS83	Gene names	Lrrc40
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 40.

PHLPP_HUMAN
NC score	0.040264 (rank : 73)	θ value	6.88961 (rank : 73)
Query Neighborhood Hits	78	Target Neighborhood Hits	604	Shared Neighborhood Hits	35
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

LRC33_HUMAN
NC score	0.040062 (rank : 74)	θ value	5.27518 (rank : 67)
Query Neighborhood Hits	78	Target Neighborhood Hits	293	Shared Neighborhood Hits	37
SwissProt Accessions	Q86YC3	Gene names	LRRC33
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 33 precursor.

FLII_MOUSE
NC score	0.039373 (rank : 75)	θ value	3.0926 (rank : 59)
Query Neighborhood Hits	78	Target Neighborhood Hits	304	Shared Neighborhood Hits	34
SwissProt Accessions	Q9JJ28, Q8K095, Q8VI44	Gene names	Flii, Fli1, Fliih
Domain Architecture	No domain graphic available
Description	Protein flightless-1 homolog.

LRC15_HUMAN
NC score	0.036479 (rank : 76)	θ value	0.365318 (rank : 47)
Query Neighborhood Hits	78	Target Neighborhood Hits	305	Shared Neighborhood Hits	36
SwissProt Accessions	Q8TF66, Q7RTN7	Gene names	LRRC15, LIB
Domain Architecture
Description	Leucine-rich repeat-containing protein 15 precursor (hLib).

ECM2_HUMAN
NC score	0.036296 (rank : 77)	θ value	1.81305 (rank : 54)
Query Neighborhood Hits	78	Target Neighborhood Hits	402	Shared Neighborhood Hits	34
SwissProt Accessions	O94769	Gene names	ECM2
Domain Architecture
Description	Extracellular matrix protein 2 precursor (Matrix glycoprotein SC1/ECM2).

A2GL_HUMAN
NC score	0.035367 (rank : 78)	θ value	0.0330416 (rank : 33)
Query Neighborhood Hits	78	Target Neighborhood Hits	281	Shared Neighborhood Hits	28
SwissProt Accessions	P02750, Q8N4F5, Q96QZ4	Gene names	LRG1, LRG
Domain Architecture
Description	Leucine-rich alpha-2-glycoprotein precursor (LRG).

FLII_HUMAN
NC score	0.034958 (rank : 79)	θ value	4.03905 (rank : 62)
Query Neighborhood Hits	78	Target Neighborhood Hits	318	Shared Neighborhood Hits	34
SwissProt Accessions	Q13045	Gene names	FLII, FLIL
Domain Architecture
Description	Protein flightless-1 homolog.

LRCH4_MOUSE
NC score	0.033898 (rank : 80)	θ value	1.06291 (rank : 52)
Query Neighborhood Hits	78	Target Neighborhood Hits	302	Shared Neighborhood Hits	28
SwissProt Accessions	Q921G6	Gene names	Lrch4
Domain Architecture
Description	Leucine-rich repeats and calponin homology domain-containing protein 4.

AN32D_HUMAN
NC score	0.031947 (rank : 81)	θ value	0.125558 (rank : 39)
Query Neighborhood Hits	78	Target Neighborhood Hits	95	Shared Neighborhood Hits	12
SwissProt Accessions	O95626, Q6NTC4	Gene names	ANP32D, PP32R2
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member D (Phosphoprotein 32-related protein 2) (Tumorigenic protein pp32r2).

TLR11_MOUSE
NC score	0.030331 (rank : 82)	θ value	8.99809 (rank : 77)
Query Neighborhood Hits	78	Target Neighborhood Hits	293	Shared Neighborhood Hits	32
SwissProt Accessions	Q6R5P0	Gene names	Tlr11
Domain Architecture	No domain graphic available
Description	Toll-like receptor 11 precursor.

LGR5_HUMAN
NC score	0.027804 (rank : 83)	θ value	8.99809 (rank : 74)
Query Neighborhood Hits	78	Target Neighborhood Hits	452	Shared Neighborhood Hits	35
SwissProt Accessions	O75473, Q9UP75	Gene names	LGR5, GPR49, GPR67
Domain Architecture
Description	Leucine-rich repeat-containing G-protein coupled receptor 5 precursor (Orphan G-protein coupled receptor HG38) (G-protein coupled receptor 49) (G-protein coupled receptor 67).

LRC24_HUMAN
NC score	0.027329 (rank : 84)	θ value	1.06291 (rank : 51)
Query Neighborhood Hits	78	Target Neighborhood Hits	404	Shared Neighborhood Hits	28
SwissProt Accessions	Q50LG9	Gene names	LRRC24
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 24 precursor.

GP125_HUMAN
NC score	0.027262 (rank : 85)	θ value	0.365318 (rank : 46)
Query Neighborhood Hits	78	Target Neighborhood Hits	327	Shared Neighborhood Hits	28
SwissProt Accessions	Q8IWK6, Q6UXK9, Q86SQ5, Q8TC55	Gene names	GPR125
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 125 precursor.

GP125_MOUSE
NC score	0.025740 (rank : 86)	θ value	3.0926 (rank : 60)
Query Neighborhood Hits	78	Target Neighborhood Hits	329	Shared Neighborhood Hits	27
SwissProt Accessions	Q7TT36, Q6PE67, Q8VE71	Gene names	Gpr125
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 125 precursor.

LRC10_HUMAN
NC score	0.025547 (rank : 87)	θ value	8.99809 (rank : 75)
Query Neighborhood Hits	78	Target Neighborhood Hits	200	Shared Neighborhood Hits	22
SwissProt Accessions	Q5BKY1, Q6ZVY4	Gene names	LRRC10
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 10.

TLR9_HUMAN
NC score	0.023799 (rank : 88)	θ value	4.03905 (rank : 64)
Query Neighborhood Hits	78	Target Neighborhood Hits	295	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NR96, Q6UVZ2, Q9HD68, Q9HD69, Q9HD70, Q9NYC2, Q9NYC3	Gene names	TLR9
Domain Architecture
Description	Toll-like receptor 9 precursor (CD289 antigen).

LGR4_HUMAN
NC score	0.023674 (rank : 89)	θ value	2.36792 (rank : 55)
Query Neighborhood Hits	78	Target Neighborhood Hits	481	Shared Neighborhood Hits	31
SwissProt Accessions	Q9BXB1, Q9NYD1	Gene names	LGR4, GPR48
Domain Architecture
Description	Leucine-rich repeat-containing G-protein coupled receptor 4 precursor (G-protein coupled receptor 48).

AN32C_HUMAN
NC score	0.022812 (rank : 90)	θ value	5.27518 (rank : 66)
Query Neighborhood Hits	78	Target Neighborhood Hits	100	Shared Neighborhood Hits	9
SwissProt Accessions	O43423	Gene names	ANP32C, PP32R1
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member C (Phosphoprotein 32-related protein 1) (Tumorigenic protein pp32r1).

LRC24_MOUSE
NC score	0.022324 (rank : 91)	θ value	4.03905 (rank : 63)
Query Neighborhood Hits	78	Target Neighborhood Hits	387	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BHA1	Gene names	Lrrc24
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 24 precursor.

ALS_MOUSE
NC score	0.021027 (rank : 92)	θ value	6.88961 (rank : 70)
Query Neighborhood Hits	78	Target Neighborhood Hits	275	Shared Neighborhood Hits	26
SwissProt Accessions	P70389, Q9DBI7	Gene names	Igfals, Albs, Als
Domain Architecture
Description	Insulin-like growth factor-binding protein complex acid labile chain precursor (ALS).

OPT_HUMAN
NC score	0.020216 (rank : 93)	θ value	5.27518 (rank : 68)
Query Neighborhood Hits	78	Target Neighborhood Hits	255	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UBM4	Gene names	OPTC, OPT
Domain Architecture	No domain graphic available
Description	Opticin precursor (Oculoglycan).

I17RA_HUMAN
NC score	0.008747 (rank : 94)	θ value	6.88961 (rank : 71)
Query Neighborhood Hits	78	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	Q96F46, O43844	Gene names	IL17RA, IL17R
Domain Architecture	No domain graphic available
Description	Interleukin-17 receptor A precursor (IL-17 receptor).