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Network neighborhood for query Sequence : NAL11_HUMAN

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NAL11_HUMAN
SwissProt Accessions	P59045, Q53ZZ0, Q8NBF5	Gene names	NALP11, NOD17, PYPAF6
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 11 (PYRIN-containing APAF1-like protein 6) (Nucleotide-binding oligomerization domain protein 17).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

NAL11_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	66	Target Neighborhood Hits	66	Shared Neighborhood Hits	66
SwissProt Accessions	P59045, Q53ZZ0, Q8NBF5	Gene names	NALP11, NOD17, PYPAF6
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 11 (PYRIN-containing APAF1-like protein 6) (Nucleotide-binding oligomerization domain protein 17).

NALP4_HUMAN
θ value	1.37145e-157 (rank : 2)	NC score	0.965805 (rank : 2)
Query Neighborhood Hits	66	Target Neighborhood Hits	81	Shared Neighborhood Hits	35
SwissProt Accessions	Q96MN2, Q86W87, Q96AY6	Gene names	NALP4, PAN2, PYPAF4, RNH2
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 4 (PYRIN-containing APAF1-like protein 4) (PAAD and NACHT-containing protein 2) (PYRIN and NACHT- containing protein 2) (Ribonuclease inhibitor 2).

NAL14_HUMAN
θ value	4.90052e-139 (rank : 3)	NC score	0.964459 (rank : 3)
Query Neighborhood Hits	66	Target Neighborhood Hits	76	Shared Neighborhood Hits	37
SwissProt Accessions	Q86W24, Q7RTR6	Gene names	NALP14, NOD5
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 14 (Nucleotide-binding oligomerization domain protein 5).

NAL13_HUMAN
θ value	5.10665e-112 (rank : 4)	NC score	0.959826 (rank : 4)
Query Neighborhood Hits	66	Target Neighborhood Hits	93	Shared Neighborhood Hits	33
SwissProt Accessions	Q86W25, Q7RTR5	Gene names	NALP13, NOD14
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 13 (Nucleotide-binding oligomerization domain protein 14).

NAL12_HUMAN
θ value	1.06727e-101 (rank : 5)	NC score	0.947435 (rank : 8)
Query Neighborhood Hits	66	Target Neighborhood Hits	96	Shared Neighborhood Hits	40
SwissProt Accessions	P59046, Q8NEU4, Q9BY26	Gene names	NALP12, PYPAF7, RNO
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 12 (PYRIN-containing APAF1-like protein 7) (Monarch-1) (Regulated by nitric oxide).

CIAS1_HUMAN
θ value	1.88391e-98 (rank : 6)	NC score	0.946033 (rank : 9)
Query Neighborhood Hits	66	Target Neighborhood Hits	76	Shared Neighborhood Hits	34
SwissProt Accessions	Q96P20, O75434, Q59H68, Q5JQS8, Q5JQS9, Q6TG35, Q8TCW0, Q8TEU9, Q8WXH9	Gene names	CIAS1, NALP3, PYPAF1
Domain Architecture
Description	Cold autoinflammatory syndrome 1 protein (Cryopyrin) (NACHT-, LRR- and PYD-containing protein 3) (PYRIN-containing APAF1-like protein 1) (Angiotensin/vasopressin receptor AII/AVP-like).

NALP5_HUMAN
θ value	7.15887e-98 (rank : 7)	NC score	0.956804 (rank : 5)
Query Neighborhood Hits	66	Target Neighborhood Hits	88	Shared Neighborhood Hits	36
SwissProt Accessions	P59047, Q86W29	Gene names	NALP5, MATER
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Mater protein homolog).

NALP2_HUMAN
θ value	1.59483e-97 (rank : 8)	NC score	0.948401 (rank : 7)
Query Neighborhood Hits	66	Target Neighborhood Hits	65	Shared Neighborhood Hits	32
SwissProt Accessions	Q9NX02, Q53FL5, Q59G09, Q8IXT0, Q9BVN5, Q9H6G6, Q9HAV9, Q9NWK3	Gene names	NALP2, NBS1, PAN1, PYPAF2
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 2 (PYRIN domain and NACHT domain-containing protein 1) (PYRIN-containing APAF1-like protein 2) (Nucleotide-binding site protein 1).

CIAS1_MOUSE
θ value	7.91507e-97 (rank : 9)	NC score	0.949820 (rank : 6)
Query Neighborhood Hits	66	Target Neighborhood Hits	67	Shared Neighborhood Hits	36
SwissProt Accessions	Q8R4B8, Q6JEL0	Gene names	Cias1, Mmig1, Nalp3, Pypaf1
Domain Architecture
Description	Cold autoinflammatory syndrome 1 protein homolog (PYRIN-containing APAF1-like protein 1) (Mast cell maturation-associated-inducible protein 1) (Cryopyrin).

NALP5_MOUSE
θ value	3.44127e-92 (rank : 10)	NC score	0.888967 (rank : 14)
Query Neighborhood Hits	66	Target Neighborhood Hits	560	Shared Neighborhood Hits	34
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

NALP7_HUMAN
θ value	5.15425e-80 (rank : 11)	NC score	0.944051 (rank : 10)
Query Neighborhood Hits	66	Target Neighborhood Hits	65	Shared Neighborhood Hits	30
SwissProt Accessions	Q8WX94, Q7RTR1	Gene names	NALP7, NOD12, PYPAF3
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 7 (PYRIN-containing APAF1-like protein 3).

NALP1_HUMAN
θ value	5.35859e-61 (rank : 12)	NC score	0.891391 (rank : 13)
Query Neighborhood Hits	66	Target Neighborhood Hits	138	Shared Neighborhood Hits	34
SwissProt Accessions	Q9C000, Q9BZZ8, Q9BZZ9, Q9HAV8, Q9UFT4, Q9Y2E0	Gene names	NALP1, CARD7, DEFCAP, KIAA0926, NAC
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 1 (Death effector filament- forming ced-4-like apoptosis protein) (Nucleotide-binding domain and caspase recruitment domain) (Caspase recruitment domain protein 7).

RINI_MOUSE
θ value	4.70527e-49 (rank : 13)	NC score	0.886036 (rank : 15)
Query Neighborhood Hits	66	Target Neighborhood Hits	87	Shared Neighborhood Hits	38
SwissProt Accessions	Q91VI7, Q924P4	Gene names	Rnh1, Rnh
Domain Architecture	No domain graphic available
Description	Ribonuclease inhibitor (Ribonuclease/angiogenin inhibitor 1).

RINI_HUMAN
θ value	3.04986e-48 (rank : 14)	NC score	0.885689 (rank : 16)
Query Neighborhood Hits	66	Target Neighborhood Hits	78	Shared Neighborhood Hits	38
SwissProt Accessions	P13489	Gene names	RNH1, PRI, RNH
Domain Architecture
Description	Ribonuclease inhibitor (Ribonuclease/angiogenin inhibitor 1) (RAI) (Placental ribonuclease inhibitor) (RNase inhibitor) (RI).

NALP6_MOUSE
θ value	9.18288e-45 (rank : 15)	NC score	0.899936 (rank : 12)
Query Neighborhood Hits	66	Target Neighborhood Hits	55	Shared Neighborhood Hits	30
SwissProt Accessions	Q91WS2, Q8K0L4	Gene names	Nalp6, Pypaf5
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 6 (PYRIN-containing APAF1-like protein 5-like).

NALP6_HUMAN
θ value	9.50281e-42 (rank : 16)	NC score	0.900208 (rank : 11)
Query Neighborhood Hits	66	Target Neighborhood Hits	52	Shared Neighborhood Hits	28
SwissProt Accessions	P59044	Gene names	NALP6, PYPAF5
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 6 (PYRIN-containing APAF1-like protein 5).

NAL10_MOUSE
θ value	1.37539e-32 (rank : 17)	NC score	0.847339 (rank : 18)
Query Neighborhood Hits	66	Target Neighborhood Hits	46	Shared Neighborhood Hits	23
SwissProt Accessions	Q8CCN1	Gene names	Nalp10, Pynod
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 10.

NAL10_HUMAN
θ value	2.19584e-30 (rank : 18)	NC score	0.848394 (rank : 17)
Query Neighborhood Hits	66	Target Neighborhood Hits	55	Shared Neighborhood Hits	23
SwissProt Accessions	Q86W26, Q6JGT0	Gene names	NALP10, NOD8, PYNOD
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 10 (Nucleotide-binding oligomerization domain protein 8).

CAR15_MOUSE
θ value	1.29331e-14 (rank : 19)	NC score	0.678431 (rank : 19)
Query Neighborhood Hits	66	Target Neighborhood Hits	93	Shared Neighborhood Hits	38
SwissProt Accessions	Q8K3Z0	Gene names	Card15, Nod2
Domain Architecture
Description	Caspase recruitment domain-containing protein 15 (Protein Nod2).

CAR15_HUMAN
θ value	2.28291e-11 (rank : 20)	NC score	0.659765 (rank : 20)
Query Neighborhood Hits	66	Target Neighborhood Hits	77	Shared Neighborhood Hits	37
SwissProt Accessions	Q9HC29, Q96RH5, Q96RH6, Q96RH8	Gene names	CARD15, IBD1, NOD2
Domain Architecture
Description	Caspase recruitment domain-containing protein 15 (Protein Nod2) (Inflammatory bowel disease protein 1).

LRC34_HUMAN
θ value	4.76016e-09 (rank : 21)	NC score	0.538934 (rank : 25)
Query Neighborhood Hits	66	Target Neighborhood Hits	67	Shared Neighborhood Hits	35
SwissProt Accessions	Q8IZ02	Gene names	LRRC34
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 34.

C2TA_MOUSE
θ value	5.81887e-07 (rank : 22)	NC score	0.567438 (rank : 23)
Query Neighborhood Hits	66	Target Neighborhood Hits	131	Shared Neighborhood Hits	34
SwissProt Accessions	P79621, O46787, O78036, O78109, Q31115, Q9TPP1	Gene names	Ciita, C2ta, Mhc2ta
Domain Architecture
Description	MHC class II transactivator (CIITA).

CARD4_HUMAN
θ value	9.92553e-07 (rank : 23)	NC score	0.635243 (rank : 21)
Query Neighborhood Hits	66	Target Neighborhood Hits	102	Shared Neighborhood Hits	40
SwissProt Accessions	Q9Y239, Q8IWF5	Gene names	CARD4, NOD1
Domain Architecture
Description	Caspase recruitment domain-containing protein 4 (Protein Nod1).

LRC31_HUMAN
θ value	8.40245e-06 (rank : 24)	NC score	0.499539 (rank : 26)
Query Neighborhood Hits	66	Target Neighborhood Hits	139	Shared Neighborhood Hits	39
SwissProt Accessions	Q6UY01, Q8N848, Q9H5N5	Gene names	LRRC31
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 31.

C2TA_HUMAN
θ value	0.000121331 (rank : 25)	NC score	0.553200 (rank : 24)
Query Neighborhood Hits	66	Target Neighborhood Hits	190	Shared Neighborhood Hits	32
SwissProt Accessions	P33076	Gene names	CIITA, MHC2TA
Domain Architecture
Description	MHC class II transactivator (CIITA).

LRC45_MOUSE
θ value	0.00035302 (rank : 26)	NC score	0.173607 (rank : 34)
Query Neighborhood Hits	66	Target Neighborhood Hits	959	Shared Neighborhood Hits	34
SwissProt Accessions	Q8CIM1, Q3U5Z2	Gene names	Lrrc45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

CARD4_MOUSE
θ value	0.000602161 (rank : 27)	NC score	0.629426 (rank : 22)
Query Neighborhood Hits	66	Target Neighborhood Hits	85	Shared Neighborhood Hits	37
SwissProt Accessions	Q8BHB0, Q8BUT6	Gene names	Card4
Domain Architecture
Description	Caspase recruitment domain-containing protein 4.

LRC34_MOUSE
θ value	0.00298849 (rank : 28)	NC score	0.494649 (rank : 27)
Query Neighborhood Hits	66	Target Neighborhood Hits	58	Shared Neighborhood Hits	33
SwissProt Accessions	Q9DAM1	Gene names	Lrrc34
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 34.

LRC45_HUMAN
θ value	0.00509761 (rank : 29)	NC score	0.163807 (rank : 35)
Query Neighborhood Hits	66	Target Neighborhood Hits	933	Shared Neighborhood Hits	33
SwissProt Accessions	Q96CN5	Gene names	LRRC45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

CD14_MOUSE
θ value	0.0431538 (rank : 30)	NC score	0.086027 (rank : 45)
Query Neighborhood Hits	66	Target Neighborhood Hits	104	Shared Neighborhood Hits	14
SwissProt Accessions	P10810	Gene names	Cd14
Domain Architecture
Description	Monocyte differentiation antigen CD14 precursor (Myeloid cell-specific leucine-rich glycoprotein).

CAR12_HUMAN
θ value	0.0736092 (rank : 31)	NC score	0.266749 (rank : 31)
Query Neighborhood Hits	66	Target Neighborhood Hits	132	Shared Neighborhood Hits	38
SwissProt Accessions	Q9NPP4, Q96J81, Q96J82, Q96J83	Gene names	CARD12, CLAN, CLAN1
Domain Architecture
Description	Caspase recruitment domain-containing protein 12 (Ice protease- activating factor) (Ipaf) (CARD, LRR, and NACHT-containing protein) (Clan protein).

LRC14_HUMAN
θ value	0.0736092 (rank : 32)	NC score	0.105041 (rank : 44)
Query Neighborhood Hits	66	Target Neighborhood Hits	57	Shared Neighborhood Hits	20
SwissProt Accessions	Q15048	Gene names	LRRC14, KIAA0014
Domain Architecture
Description	Leucine-rich repeat-containing protein 14.

LRC15_HUMAN
θ value	0.125558 (rank : 33)	NC score	0.023432 (rank : 58)
Query Neighborhood Hits	66	Target Neighborhood Hits	305	Shared Neighborhood Hits	21
SwissProt Accessions	Q8TF66, Q7RTN7	Gene names	LRRC15, LIB
Domain Architecture
Description	Leucine-rich repeat-containing protein 15 precursor (hLib).

LGR5_MOUSE
θ value	0.279714 (rank : 34)	NC score	0.018960 (rank : 63)
Query Neighborhood Hits	66	Target Neighborhood Hits	484	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Z1P4	Gene names	Lgr5, Fex, Gpr49
Domain Architecture
Description	Leucine-rich repeat-containing G-protein coupled receptor 5 precursor (G-protein coupled receptor 49) (Orphan G-protein coupled receptor FEX).

IL6RA_HUMAN
θ value	0.47712 (rank : 35)	NC score	0.021161 (rank : 60)
Query Neighborhood Hits	66	Target Neighborhood Hits	96	Shared Neighborhood Hits	2
SwissProt Accessions	P08887, Q16202, Q53EQ7, Q5FWG2, Q5VZ23	Gene names	IL6R
Domain Architecture
Description	Interleukin-6 receptor alpha chain precursor (IL-6R-alpha) (IL-6R 1) (Membrane glycoprotein 80) (gp80) (CD126 antigen).

LGR5_HUMAN
θ value	1.06291 (rank : 36)	NC score	0.020132 (rank : 61)
Query Neighborhood Hits	66	Target Neighborhood Hits	452	Shared Neighborhood Hits	23
SwissProt Accessions	O75473, Q9UP75	Gene names	LGR5, GPR49, GPR67
Domain Architecture
Description	Leucine-rich repeat-containing G-protein coupled receptor 5 precursor (Orphan G-protein coupled receptor HG38) (G-protein coupled receptor 49) (G-protein coupled receptor 67).

LRC40_HUMAN
θ value	1.38821 (rank : 37)	NC score	0.019344 (rank : 62)
Query Neighborhood Hits	66	Target Neighborhood Hits	313	Shared Neighborhood Hits	22
SwissProt Accessions	Q9H9A6, Q9BTR7, Q9NSK1, Q9NXC1	Gene names	LRRC40
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 40.

NU133_MOUSE
θ value	1.38821 (rank : 38)	NC score	0.018509 (rank : 64)
Query Neighborhood Hits	66	Target Neighborhood Hits	34	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R0G9	Gene names	Nup133
Domain Architecture
Description	Nuclear pore complex protein Nup133 (Nucleoporin Nup133) (133 kDa nucleoporin).

MCM3A_HUMAN
θ value	1.81305 (rank : 39)	NC score	0.016014 (rank : 67)
Query Neighborhood Hits	66	Target Neighborhood Hits	86	Shared Neighborhood Hits	2
SwissProt Accessions	O60318, Q9UMT4	Gene names	MCM3AP, GANP, KIAA0572, MAP80
Domain Architecture
Description	80 kDa MCM3-associated protein (GANP protein).

PHLPL_HUMAN
θ value	1.81305 (rank : 40)	NC score	0.028087 (rank : 55)
Query Neighborhood Hits	66	Target Neighborhood Hits	310	Shared Neighborhood Hits	23
SwissProt Accessions	Q6ZVD8, Q9NV17, Q9Y2E3	Gene names	PHLPPL, KIAA0931
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat protein phosphatase-like (EC 3.1.3.16).

ABCAD_HUMAN
θ value	2.36792 (rank : 41)	NC score	0.007031 (rank : 76)
Query Neighborhood Hits	66	Target Neighborhood Hits	207	Shared Neighborhood Hits	4
SwissProt Accessions	Q86UQ4, Q6ZTT7, Q86WI2, Q8N248	Gene names	ABCA13
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 13.

CF154_HUMAN
θ value	2.36792 (rank : 42)	NC score	0.477964 (rank : 28)
Query Neighborhood Hits	66	Target Neighborhood Hits	36	Shared Neighborhood Hits	26
SwissProt Accessions	Q5JTD7	Gene names	C6orf154
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf154.

LRC8A_MOUSE
θ value	2.36792 (rank : 43)	NC score	0.017445 (rank : 65)
Query Neighborhood Hits	66	Target Neighborhood Hits	274	Shared Neighborhood Hits	22
SwissProt Accessions	Q80WG5	Gene names	Lrrc8a, Lrrc8
Domain Architecture
Description	Leucine-rich repeat-containing protein 8A.

ORC4_MOUSE
θ value	3.0926 (rank : 44)	NC score	0.015554 (rank : 69)
Query Neighborhood Hits	66	Target Neighborhood Hits	34	Shared Neighborhood Hits	2
SwissProt Accessions	O88708, Q9QYX1	Gene names	Orc4l, Orc4
Domain Architecture
Description	Origin recognition complex subunit 4.

TMOD2_MOUSE
θ value	3.0926 (rank : 45)	NC score	0.047629 (rank : 51)
Query Neighborhood Hits	66	Target Neighborhood Hits	41	Shared Neighborhood Hits	15
SwissProt Accessions	Q9JKK7, Q9JLH9	Gene names	Tmod2
Domain Architecture
Description	Tropomodulin-2 (Neuronal tropomodulin) (N-Tmod).

TMOD2_HUMAN
θ value	4.03905 (rank : 46)	NC score	0.054596 (rank : 48)
Query Neighborhood Hits	66	Target Neighborhood Hits	29	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NZR1	Gene names	TMOD2, NTMOD
Domain Architecture
Description	Tropomodulin-2 (Neuronal tropomodulin) (N-Tmod).

ETBR2_MOUSE
θ value	5.27518 (rank : 47)	NC score	0.003256 (rank : 78)
Query Neighborhood Hits	66	Target Neighborhood Hits	487	Shared Neighborhood Hits	3
SwissProt Accessions	Q99JG2, O88313, Q80UB9, Q99JG1	Gene names	Gpr37l1, Etbrlp2
Domain Architecture	No domain graphic available
Description	Endothelin B receptor-like protein 2 precursor (ETBR-LP-2) (G-protein coupled receptor 37-like 1).

LRC8A_HUMAN
θ value	5.27518 (rank : 48)	NC score	0.017000 (rank : 66)
Query Neighborhood Hits	66	Target Neighborhood Hits	274	Shared Neighborhood Hits	22
SwissProt Accessions	Q8IWT6, Q6UXM2, Q8NCI0, Q9P2B1	Gene names	LRRC8A, KIAA1437, LRRC8
Domain Architecture
Description	Leucine-rich repeat-containing protein 8A.

PHLPP_HUMAN
θ value	5.27518 (rank : 49)	NC score	0.030302 (rank : 54)
Query Neighborhood Hits	66	Target Neighborhood Hits	604	Shared Neighborhood Hits	24
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

PTN22_HUMAN
θ value	5.27518 (rank : 50)	NC score	0.002621 (rank : 81)
Query Neighborhood Hits	66	Target Neighborhood Hits	109	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y2R2, O95063, O95064	Gene names	PTPN22, PTPN8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP) (Lymphoid phosphatase) (LyP).

ABCAC_HUMAN
θ value	6.88961 (rank : 51)	NC score	0.004975 (rank : 77)
Query Neighborhood Hits	66	Target Neighborhood Hits	123	Shared Neighborhood Hits	3
SwissProt Accessions	Q86UK0, Q8IZW6, Q96JT3, Q9Y4M5	Gene names	ABCA12, ABC12
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 12 (ATP-binding cassette transporter 12) (ATP-binding cassette 12).

CF072_HUMAN
θ value	6.88961 (rank : 52)	NC score	0.011231 (rank : 72)
Query Neighborhood Hits	66	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NU53	Gene names	C6orf72
Domain Architecture	No domain graphic available
Description	Protein C6orf72 precursor.

ETBR2_HUMAN
θ value	6.88961 (rank : 53)	NC score	0.002839 (rank : 80)
Query Neighborhood Hits	66	Target Neighborhood Hits	489	Shared Neighborhood Hits	3
SwissProt Accessions	O60883, Q86VP7	Gene names	GPR37L1, ETBRLP2
Domain Architecture
Description	Endothelin B receptor-like protein 2 precursor (ETBR-LP-2) (G-protein coupled receptor 37-like 1).

GCN1L_HUMAN
θ value	6.88961 (rank : 54)	NC score	0.009881 (rank : 74)
Query Neighborhood Hits	66	Target Neighborhood Hits	112	Shared Neighborhood Hits	2
SwissProt Accessions	Q92616, O95001, O95651, Q6P2S3, Q86X65, Q8N5I5, Q8WU80, Q99736, Q9UE60	Gene names	GCN1L1, KIAA0219
Domain Architecture	No domain graphic available
Description	GCN1-like protein 1 (HsGCN1).

LRC32_HUMAN
θ value	6.88961 (rank : 55)	NC score	0.015956 (rank : 68)
Query Neighborhood Hits	66	Target Neighborhood Hits	303	Shared Neighborhood Hits	21
SwissProt Accessions	Q14392, Q86V06	Gene names	LRRC32, GARP
Domain Architecture
Description	Leucine-rich repeat-containing protein 32 precursor (GARP protein) (Garpin) (Glycoprotein A repetitions predominant).

LRC33_MOUSE
θ value	6.88961 (rank : 56)	NC score	0.023447 (rank : 57)
Query Neighborhood Hits	66	Target Neighborhood Hits	296	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BMT4, Q3TIA8, Q8BTT4, Q8BUI7, Q8BY16, Q8R063	Gene names	Lrrc33
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 33 precursor.

LRCH3_HUMAN
θ value	6.88961 (rank : 57)	NC score	0.012942 (rank : 71)
Query Neighborhood Hits	66	Target Neighborhood Hits	270	Shared Neighborhood Hits	17
SwissProt Accessions	Q96II8, Q96FP9, Q9NT52	Gene names	LRCH3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and calponin homology domain-containing protein 3 precursor.

LRCH3_MOUSE
θ value	6.88961 (rank : 58)	NC score	0.014708 (rank : 70)
Query Neighborhood Hits	66	Target Neighborhood Hits	257	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BVU0, Q3U222, Q3UZ74	Gene names	Lrch3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and calponin homology domain-containing protein 3 precursor.

TMOD1_MOUSE
θ value	6.88961 (rank : 59)	NC score	0.042653 (rank : 52)
Query Neighborhood Hits	66	Target Neighborhood Hits	28	Shared Neighborhood Hits	15
SwissProt Accessions	P49813, Q9ERR9	Gene names	Tmod1, Tmod
Domain Architecture
Description	Tropomodulin-1 (Erythrocyte tropomodulin) (E-Tmod).

TMOD3_MOUSE
θ value	6.88961 (rank : 60)	NC score	0.049085 (rank : 50)
Query Neighborhood Hits	66	Target Neighborhood Hits	34	Shared Neighborhood Hits	18
SwissProt Accessions	Q9JHJ0, Q3TIT1	Gene names	Tmod3
Domain Architecture
Description	Tropomodulin-3 (Ubiquitous tropomodulin) (U-Tmod).

U520_HUMAN
θ value	6.88961 (rank : 61)	NC score	0.007470 (rank : 75)
Query Neighborhood Hits	66	Target Neighborhood Hits	88	Shared Neighborhood Hits	2
SwissProt Accessions	O75643, O94884, Q6PX59, Q96IF2, Q9H7S0	Gene names	ASCC3L1, HELIC2, KIAA0788
Domain Architecture	No domain graphic available
Description	U5 small nuclear ribonucleoprotein 200 kDa helicase (EC 3.6.1.-) (U5 snRNP-specific 200 kDa protein) (U5-200KD) (Activating signal cointegrator 1 complex subunit 3-like 1) (BRR2 homolog).

LRC15_MOUSE
θ value	8.99809 (rank : 62)	NC score	0.021262 (rank : 59)
Query Neighborhood Hits	66	Target Neighborhood Hits	305	Shared Neighborhood Hits	23
SwissProt Accessions	Q80X72	Gene names	Lrrc15
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 15 precursor.

LRTM2_HUMAN
θ value	8.99809 (rank : 63)	NC score	0.010126 (rank : 73)
Query Neighborhood Hits	66	Target Neighborhood Hits	282	Shared Neighborhood Hits	20
SwissProt Accessions	O43300, Q7L770	Gene names	LRRTM2, KIAA0416, LRRN2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat transmembrane neuronal protein 2 precursor (Leucine-rich repeat neuronal 2 protein).

PHLPL_MOUSE
θ value	8.99809 (rank : 64)	NC score	0.025291 (rank : 56)
Query Neighborhood Hits	66	Target Neighborhood Hits	303	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BXA7, Q8BX96	Gene names	Phlppl
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat protein phosphatase-like (EC 3.1.3.16).

PLCB4_HUMAN
θ value	8.99809 (rank : 65)	NC score	0.003124 (rank : 79)
Query Neighborhood Hits	66	Target Neighborhood Hits	658	Shared Neighborhood Hits	4
SwissProt Accessions	Q15147, Q5JYS8, Q5JYT0, Q5JYT4, Q9BQW5, Q9BQW6, Q9BQW8, Q9UJQ2	Gene names	PLCB4
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 4 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-4) (PLC-beta-4).

TMOD1_HUMAN
θ value	8.99809 (rank : 66)	NC score	0.041135 (rank : 53)
Query Neighborhood Hits	66	Target Neighborhood Hits	32	Shared Neighborhood Hits	15
SwissProt Accessions	P28289, Q9BUF1	Gene names	TMOD1, TMOD
Domain Architecture
Description	Tropomodulin-1 (Erythrocyte tropomodulin) (E-Tmod).

ASC_HUMAN
θ value	θ > 10 (rank : 67)	NC score	0.183589 (rank : 33)
Query Neighborhood Hits	66	Target Neighborhood Hits	18	Shared Neighborhood Hits	10
SwissProt Accessions	Q9ULZ3, Q96D12, Q9BSZ5, Q9HBD0, Q9NXJ8	Gene names	PYCARD, ASC, CARD5, TMS1
Domain Architecture
Description	Apoptosis-associated speck-like protein containing a CARD (hASC) (PYD and CARD domain-containing protein) (Target of methylation-induced silencing 1) (Caspase recruitment domain-containing protein 5).

ASC_MOUSE
θ value	θ > 10 (rank : 68)	NC score	0.238286 (rank : 32)
Query Neighborhood Hits	66	Target Neighborhood Hits	17	Shared Neighborhood Hits	11
SwissProt Accessions	Q9EPB4, Q9D2W9	Gene names	Pycard, Asc
Domain Architecture
Description	Apoptosis-associated speck-like protein containing a CARD (mASC) (PYD and CARD domain-containing protein).

BIR1A_MOUSE
θ value	θ > 10 (rank : 69)	NC score	0.141514 (rank : 37)
Query Neighborhood Hits	66	Target Neighborhood Hits	94	Shared Neighborhood Hits	23
SwissProt Accessions	Q9QWK5, Q9JIB5, Q9R017	Gene names	Birc1a, Naip, Naip1
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1a (Neuronal apoptosis inhibitory protein 1).

BIR1B_MOUSE
θ value	θ > 10 (rank : 70)	NC score	0.121512 (rank : 42)
Query Neighborhood Hits	66	Target Neighborhood Hits	93	Shared Neighborhood Hits	23
SwissProt Accessions	Q9QUK4, O09124, Q9R030	Gene names	Birc1b, Naip-rs6, Naip2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1b (Neuronal apoptosis inhibitory protein 2).

BIR1E_MOUSE
θ value	θ > 10 (rank : 71)	NC score	0.134302 (rank : 39)
Query Neighborhood Hits	66	Target Neighborhood Hits	93	Shared Neighborhood Hits	22
SwissProt Accessions	Q9R016, O09121, O09122, P81703, Q9R029	Gene names	Birc1e, Naip-rs3, Naip5
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1e (Neuronal apoptosis inhibitory protein 5).

BIR1F_MOUSE
θ value	θ > 10 (rank : 72)	NC score	0.135270 (rank : 38)
Query Neighborhood Hits	66	Target Neighborhood Hits	88	Shared Neighborhood Hits	23
SwissProt Accessions	Q9JIB6, O09121, O09122, P81704	Gene names	Birc1f, Naip-rs4, Naip6
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1f (Neuronal apoptosis inhibitory protein 6).

BIR1G_MOUSE
θ value	θ > 10 (rank : 73)	NC score	0.127725 (rank : 40)
Query Neighborhood Hits	66	Target Neighborhood Hits	92	Shared Neighborhood Hits	22
SwissProt Accessions	Q9JIB3	Gene names	Birc1g, Naip7
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1g (Neuronal apoptosis inhibitory protein 7).

BIRC1_HUMAN
θ value	θ > 10 (rank : 74)	NC score	0.157155 (rank : 36)
Query Neighborhood Hits	66	Target Neighborhood Hits	61	Shared Neighborhood Hits	23
SwissProt Accessions	Q13075, O75857, Q13730, Q99796	Gene names	BIRC1, NAIP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1 (Neuronal apoptosis inhibitory protein).

CARD8_HUMAN
θ value	θ > 10 (rank : 75)	NC score	0.112794 (rank : 43)
Query Neighborhood Hits	66	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y2G2, Q6PGP8, Q96P82	Gene names	CARD8, KIAA0955, NDPP1
Domain Architecture
Description	Caspase recruitment domain-containing protein 8 (Apoptotic protein NDPP1) (DACAR) (CARD-inhibitor of NF-kappa-B-activating ligand) (CARDINAL) (Tumor-up-regulated CARD-containing antagonist of CASP9) (TUCAN).

MAPE_HUMAN
θ value	θ > 10 (rank : 76)	NC score	0.055698 (rank : 47)
Query Neighborhood Hits	66	Target Neighborhood Hits	24	Shared Neighborhood Hits	10
SwissProt Accessions	P78395, O43481, Q8IXN8	Gene names	PRAME, MAPE
Domain Architecture	No domain graphic available
Description	Melanoma antigen preferentially expressed in tumors (Preferentially expressed antigen of melanoma) (OPA-interacting protein 4) (OIP4).

MEFV_HUMAN
θ value	θ > 10 (rank : 77)	NC score	0.072425 (rank : 46)
Query Neighborhood Hits	66	Target Neighborhood Hits	431	Shared Neighborhood Hits	11
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

MEFV_MOUSE
θ value	θ > 10 (rank : 78)	NC score	0.126675 (rank : 41)
Query Neighborhood Hits	66	Target Neighborhood Hits	236	Shared Neighborhood Hits	11
SwissProt Accessions	Q9JJ26	Gene names	Mefv
Domain Architecture
Description	Pyrin (Marenostrin).

RGP1_HUMAN
θ value	θ > 10 (rank : 79)	NC score	0.298587 (rank : 29)
Query Neighborhood Hits	66	Target Neighborhood Hits	124	Shared Neighborhood Hits	24
SwissProt Accessions	P46060	Gene names	RANGAP1
Domain Architecture
Description	Ran GTPase-activating protein 1.

RGP1_MOUSE
θ value	θ > 10 (rank : 80)	NC score	0.284265 (rank : 30)
Query Neighborhood Hits	66	Target Neighborhood Hits	105	Shared Neighborhood Hits	24
SwissProt Accessions	P46061, Q60801	Gene names	Rangap1, Fug1
Domain Architecture
Description	Ran GTPase-activating protein 1.

TMOD4_HUMAN
θ value	θ > 10 (rank : 81)	NC score	0.052461 (rank : 49)
Query Neighborhood Hits	66	Target Neighborhood Hits	37	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NZQ9, Q8WVL3, Q9UKH2	Gene names	TMOD4
Domain Architecture
Description	Tropomodulin-4 (Skeletal muscle tropomodulin) (Sk-Tmod).

Hits sorted by NC score

NAL11_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	66	Target Neighborhood Hits	66	Shared Neighborhood Hits	66
SwissProt Accessions	P59045, Q53ZZ0, Q8NBF5	Gene names	NALP11, NOD17, PYPAF6
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 11 (PYRIN-containing APAF1-like protein 6) (Nucleotide-binding oligomerization domain protein 17).

NALP4_HUMAN
NC score	0.965805 (rank : 2)	θ value	1.37145e-157 (rank : 2)
Query Neighborhood Hits	66	Target Neighborhood Hits	81	Shared Neighborhood Hits	35
SwissProt Accessions	Q96MN2, Q86W87, Q96AY6	Gene names	NALP4, PAN2, PYPAF4, RNH2
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 4 (PYRIN-containing APAF1-like protein 4) (PAAD and NACHT-containing protein 2) (PYRIN and NACHT- containing protein 2) (Ribonuclease inhibitor 2).

NAL14_HUMAN
NC score	0.964459 (rank : 3)	θ value	4.90052e-139 (rank : 3)
Query Neighborhood Hits	66	Target Neighborhood Hits	76	Shared Neighborhood Hits	37
SwissProt Accessions	Q86W24, Q7RTR6	Gene names	NALP14, NOD5
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 14 (Nucleotide-binding oligomerization domain protein 5).

NAL13_HUMAN
NC score	0.959826 (rank : 4)	θ value	5.10665e-112 (rank : 4)
Query Neighborhood Hits	66	Target Neighborhood Hits	93	Shared Neighborhood Hits	33
SwissProt Accessions	Q86W25, Q7RTR5	Gene names	NALP13, NOD14
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 13 (Nucleotide-binding oligomerization domain protein 14).

NALP5_HUMAN
NC score	0.956804 (rank : 5)	θ value	7.15887e-98 (rank : 7)
Query Neighborhood Hits	66	Target Neighborhood Hits	88	Shared Neighborhood Hits	36
SwissProt Accessions	P59047, Q86W29	Gene names	NALP5, MATER
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Mater protein homolog).

CIAS1_MOUSE
NC score	0.949820 (rank : 6)	θ value	7.91507e-97 (rank : 9)
Query Neighborhood Hits	66	Target Neighborhood Hits	67	Shared Neighborhood Hits	36
SwissProt Accessions	Q8R4B8, Q6JEL0	Gene names	Cias1, Mmig1, Nalp3, Pypaf1
Domain Architecture
Description	Cold autoinflammatory syndrome 1 protein homolog (PYRIN-containing APAF1-like protein 1) (Mast cell maturation-associated-inducible protein 1) (Cryopyrin).

NALP2_HUMAN
NC score	0.948401 (rank : 7)	θ value	1.59483e-97 (rank : 8)
Query Neighborhood Hits	66	Target Neighborhood Hits	65	Shared Neighborhood Hits	32
SwissProt Accessions	Q9NX02, Q53FL5, Q59G09, Q8IXT0, Q9BVN5, Q9H6G6, Q9HAV9, Q9NWK3	Gene names	NALP2, NBS1, PAN1, PYPAF2
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 2 (PYRIN domain and NACHT domain-containing protein 1) (PYRIN-containing APAF1-like protein 2) (Nucleotide-binding site protein 1).

NAL12_HUMAN
NC score	0.947435 (rank : 8)	θ value	1.06727e-101 (rank : 5)
Query Neighborhood Hits	66	Target Neighborhood Hits	96	Shared Neighborhood Hits	40
SwissProt Accessions	P59046, Q8NEU4, Q9BY26	Gene names	NALP12, PYPAF7, RNO
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 12 (PYRIN-containing APAF1-like protein 7) (Monarch-1) (Regulated by nitric oxide).

CIAS1_HUMAN
NC score	0.946033 (rank : 9)	θ value	1.88391e-98 (rank : 6)
Query Neighborhood Hits	66	Target Neighborhood Hits	76	Shared Neighborhood Hits	34
SwissProt Accessions	Q96P20, O75434, Q59H68, Q5JQS8, Q5JQS9, Q6TG35, Q8TCW0, Q8TEU9, Q8WXH9	Gene names	CIAS1, NALP3, PYPAF1
Domain Architecture
Description	Cold autoinflammatory syndrome 1 protein (Cryopyrin) (NACHT-, LRR- and PYD-containing protein 3) (PYRIN-containing APAF1-like protein 1) (Angiotensin/vasopressin receptor AII/AVP-like).

NALP7_HUMAN
NC score	0.944051 (rank : 10)	θ value	5.15425e-80 (rank : 11)
Query Neighborhood Hits	66	Target Neighborhood Hits	65	Shared Neighborhood Hits	30
SwissProt Accessions	Q8WX94, Q7RTR1	Gene names	NALP7, NOD12, PYPAF3
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 7 (PYRIN-containing APAF1-like protein 3).

NALP6_HUMAN
NC score	0.900208 (rank : 11)	θ value	9.50281e-42 (rank : 16)
Query Neighborhood Hits	66	Target Neighborhood Hits	52	Shared Neighborhood Hits	28
SwissProt Accessions	P59044	Gene names	NALP6, PYPAF5
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 6 (PYRIN-containing APAF1-like protein 5).

NALP6_MOUSE
NC score	0.899936 (rank : 12)	θ value	9.18288e-45 (rank : 15)
Query Neighborhood Hits	66	Target Neighborhood Hits	55	Shared Neighborhood Hits	30
SwissProt Accessions	Q91WS2, Q8K0L4	Gene names	Nalp6, Pypaf5
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 6 (PYRIN-containing APAF1-like protein 5-like).

NALP1_HUMAN
NC score	0.891391 (rank : 13)	θ value	5.35859e-61 (rank : 12)
Query Neighborhood Hits	66	Target Neighborhood Hits	138	Shared Neighborhood Hits	34
SwissProt Accessions	Q9C000, Q9BZZ8, Q9BZZ9, Q9HAV8, Q9UFT4, Q9Y2E0	Gene names	NALP1, CARD7, DEFCAP, KIAA0926, NAC
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 1 (Death effector filament- forming ced-4-like apoptosis protein) (Nucleotide-binding domain and caspase recruitment domain) (Caspase recruitment domain protein 7).

NALP5_MOUSE
NC score	0.888967 (rank : 14)	θ value	3.44127e-92 (rank : 10)
Query Neighborhood Hits	66	Target Neighborhood Hits	560	Shared Neighborhood Hits	34
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

RINI_MOUSE
NC score	0.886036 (rank : 15)	θ value	4.70527e-49 (rank : 13)
Query Neighborhood Hits	66	Target Neighborhood Hits	87	Shared Neighborhood Hits	38
SwissProt Accessions	Q91VI7, Q924P4	Gene names	Rnh1, Rnh
Domain Architecture	No domain graphic available
Description	Ribonuclease inhibitor (Ribonuclease/angiogenin inhibitor 1).

RINI_HUMAN
NC score	0.885689 (rank : 16)	θ value	3.04986e-48 (rank : 14)
Query Neighborhood Hits	66	Target Neighborhood Hits	78	Shared Neighborhood Hits	38
SwissProt Accessions	P13489	Gene names	RNH1, PRI, RNH
Domain Architecture
Description	Ribonuclease inhibitor (Ribonuclease/angiogenin inhibitor 1) (RAI) (Placental ribonuclease inhibitor) (RNase inhibitor) (RI).

NAL10_HUMAN
NC score	0.848394 (rank : 17)	θ value	2.19584e-30 (rank : 18)
Query Neighborhood Hits	66	Target Neighborhood Hits	55	Shared Neighborhood Hits	23
SwissProt Accessions	Q86W26, Q6JGT0	Gene names	NALP10, NOD8, PYNOD
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 10 (Nucleotide-binding oligomerization domain protein 8).

NAL10_MOUSE
NC score	0.847339 (rank : 18)	θ value	1.37539e-32 (rank : 17)
Query Neighborhood Hits	66	Target Neighborhood Hits	46	Shared Neighborhood Hits	23
SwissProt Accessions	Q8CCN1	Gene names	Nalp10, Pynod
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 10.

CAR15_MOUSE
NC score	0.678431 (rank : 19)	θ value	1.29331e-14 (rank : 19)
Query Neighborhood Hits	66	Target Neighborhood Hits	93	Shared Neighborhood Hits	38
SwissProt Accessions	Q8K3Z0	Gene names	Card15, Nod2
Domain Architecture
Description	Caspase recruitment domain-containing protein 15 (Protein Nod2).

CAR15_HUMAN
NC score	0.659765 (rank : 20)	θ value	2.28291e-11 (rank : 20)
Query Neighborhood Hits	66	Target Neighborhood Hits	77	Shared Neighborhood Hits	37
SwissProt Accessions	Q9HC29, Q96RH5, Q96RH6, Q96RH8	Gene names	CARD15, IBD1, NOD2
Domain Architecture
Description	Caspase recruitment domain-containing protein 15 (Protein Nod2) (Inflammatory bowel disease protein 1).

CARD4_HUMAN
NC score	0.635243 (rank : 21)	θ value	9.92553e-07 (rank : 23)
Query Neighborhood Hits	66	Target Neighborhood Hits	102	Shared Neighborhood Hits	40
SwissProt Accessions	Q9Y239, Q8IWF5	Gene names	CARD4, NOD1
Domain Architecture
Description	Caspase recruitment domain-containing protein 4 (Protein Nod1).

CARD4_MOUSE
NC score	0.629426 (rank : 22)	θ value	0.000602161 (rank : 27)
Query Neighborhood Hits	66	Target Neighborhood Hits	85	Shared Neighborhood Hits	37
SwissProt Accessions	Q8BHB0, Q8BUT6	Gene names	Card4
Domain Architecture
Description	Caspase recruitment domain-containing protein 4.

C2TA_MOUSE
NC score	0.567438 (rank : 23)	θ value	5.81887e-07 (rank : 22)
Query Neighborhood Hits	66	Target Neighborhood Hits	131	Shared Neighborhood Hits	34
SwissProt Accessions	P79621, O46787, O78036, O78109, Q31115, Q9TPP1	Gene names	Ciita, C2ta, Mhc2ta
Domain Architecture
Description	MHC class II transactivator (CIITA).

C2TA_HUMAN
NC score	0.553200 (rank : 24)	θ value	0.000121331 (rank : 25)
Query Neighborhood Hits	66	Target Neighborhood Hits	190	Shared Neighborhood Hits	32
SwissProt Accessions	P33076	Gene names	CIITA, MHC2TA
Domain Architecture
Description	MHC class II transactivator (CIITA).

LRC34_HUMAN
NC score	0.538934 (rank : 25)	θ value	4.76016e-09 (rank : 21)
Query Neighborhood Hits	66	Target Neighborhood Hits	67	Shared Neighborhood Hits	35
SwissProt Accessions	Q8IZ02	Gene names	LRRC34
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 34.

LRC31_HUMAN
NC score	0.499539 (rank : 26)	θ value	8.40245e-06 (rank : 24)
Query Neighborhood Hits	66	Target Neighborhood Hits	139	Shared Neighborhood Hits	39
SwissProt Accessions	Q6UY01, Q8N848, Q9H5N5	Gene names	LRRC31
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 31.

LRC34_MOUSE
NC score	0.494649 (rank : 27)	θ value	0.00298849 (rank : 28)
Query Neighborhood Hits	66	Target Neighborhood Hits	58	Shared Neighborhood Hits	33
SwissProt Accessions	Q9DAM1	Gene names	Lrrc34
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 34.

CF154_HUMAN
NC score	0.477964 (rank : 28)	θ value	2.36792 (rank : 42)
Query Neighborhood Hits	66	Target Neighborhood Hits	36	Shared Neighborhood Hits	26
SwissProt Accessions	Q5JTD7	Gene names	C6orf154
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf154.

RGP1_HUMAN
NC score	0.298587 (rank : 29)	θ value	θ > 10 (rank : 79)
Query Neighborhood Hits	66	Target Neighborhood Hits	124	Shared Neighborhood Hits	24
SwissProt Accessions	P46060	Gene names	RANGAP1
Domain Architecture
Description	Ran GTPase-activating protein 1.

RGP1_MOUSE
NC score	0.284265 (rank : 30)	θ value	θ > 10 (rank : 80)
Query Neighborhood Hits	66	Target Neighborhood Hits	105	Shared Neighborhood Hits	24
SwissProt Accessions	P46061, Q60801	Gene names	Rangap1, Fug1
Domain Architecture
Description	Ran GTPase-activating protein 1.

CAR12_HUMAN
NC score	0.266749 (rank : 31)	θ value	0.0736092 (rank : 31)
Query Neighborhood Hits	66	Target Neighborhood Hits	132	Shared Neighborhood Hits	38
SwissProt Accessions	Q9NPP4, Q96J81, Q96J82, Q96J83	Gene names	CARD12, CLAN, CLAN1
Domain Architecture
Description	Caspase recruitment domain-containing protein 12 (Ice protease- activating factor) (Ipaf) (CARD, LRR, and NACHT-containing protein) (Clan protein).

ASC_MOUSE
NC score	0.238286 (rank : 32)	θ value	θ > 10 (rank : 68)
Query Neighborhood Hits	66	Target Neighborhood Hits	17	Shared Neighborhood Hits	11
SwissProt Accessions	Q9EPB4, Q9D2W9	Gene names	Pycard, Asc
Domain Architecture
Description	Apoptosis-associated speck-like protein containing a CARD (mASC) (PYD and CARD domain-containing protein).

ASC_HUMAN
NC score	0.183589 (rank : 33)	θ value	θ > 10 (rank : 67)
Query Neighborhood Hits	66	Target Neighborhood Hits	18	Shared Neighborhood Hits	10
SwissProt Accessions	Q9ULZ3, Q96D12, Q9BSZ5, Q9HBD0, Q9NXJ8	Gene names	PYCARD, ASC, CARD5, TMS1
Domain Architecture
Description	Apoptosis-associated speck-like protein containing a CARD (hASC) (PYD and CARD domain-containing protein) (Target of methylation-induced silencing 1) (Caspase recruitment domain-containing protein 5).

LRC45_MOUSE
NC score	0.173607 (rank : 34)	θ value	0.00035302 (rank : 26)
Query Neighborhood Hits	66	Target Neighborhood Hits	959	Shared Neighborhood Hits	34
SwissProt Accessions	Q8CIM1, Q3U5Z2	Gene names	Lrrc45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

LRC45_HUMAN
NC score	0.163807 (rank : 35)	θ value	0.00509761 (rank : 29)
Query Neighborhood Hits	66	Target Neighborhood Hits	933	Shared Neighborhood Hits	33
SwissProt Accessions	Q96CN5	Gene names	LRRC45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

BIRC1_HUMAN
NC score	0.157155 (rank : 36)	θ value	θ > 10 (rank : 74)
Query Neighborhood Hits	66	Target Neighborhood Hits	61	Shared Neighborhood Hits	23
SwissProt Accessions	Q13075, O75857, Q13730, Q99796	Gene names	BIRC1, NAIP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1 (Neuronal apoptosis inhibitory protein).

BIR1A_MOUSE
NC score	0.141514 (rank : 37)	θ value	θ > 10 (rank : 69)
Query Neighborhood Hits	66	Target Neighborhood Hits	94	Shared Neighborhood Hits	23
SwissProt Accessions	Q9QWK5, Q9JIB5, Q9R017	Gene names	Birc1a, Naip, Naip1
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1a (Neuronal apoptosis inhibitory protein 1).

BIR1F_MOUSE
NC score	0.135270 (rank : 38)	θ value	θ > 10 (rank : 72)
Query Neighborhood Hits	66	Target Neighborhood Hits	88	Shared Neighborhood Hits	23
SwissProt Accessions	Q9JIB6, O09121, O09122, P81704	Gene names	Birc1f, Naip-rs4, Naip6
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1f (Neuronal apoptosis inhibitory protein 6).

BIR1E_MOUSE
NC score	0.134302 (rank : 39)	θ value	θ > 10 (rank : 71)
Query Neighborhood Hits	66	Target Neighborhood Hits	93	Shared Neighborhood Hits	22
SwissProt Accessions	Q9R016, O09121, O09122, P81703, Q9R029	Gene names	Birc1e, Naip-rs3, Naip5
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1e (Neuronal apoptosis inhibitory protein 5).

BIR1G_MOUSE
NC score	0.127725 (rank : 40)	θ value	θ > 10 (rank : 73)
Query Neighborhood Hits	66	Target Neighborhood Hits	92	Shared Neighborhood Hits	22
SwissProt Accessions	Q9JIB3	Gene names	Birc1g, Naip7
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1g (Neuronal apoptosis inhibitory protein 7).

MEFV_MOUSE
NC score	0.126675 (rank : 41)	θ value	θ > 10 (rank : 78)
Query Neighborhood Hits	66	Target Neighborhood Hits	236	Shared Neighborhood Hits	11
SwissProt Accessions	Q9JJ26	Gene names	Mefv
Domain Architecture
Description	Pyrin (Marenostrin).

BIR1B_MOUSE
NC score	0.121512 (rank : 42)	θ value	θ > 10 (rank : 70)
Query Neighborhood Hits	66	Target Neighborhood Hits	93	Shared Neighborhood Hits	23
SwissProt Accessions	Q9QUK4, O09124, Q9R030	Gene names	Birc1b, Naip-rs6, Naip2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1b (Neuronal apoptosis inhibitory protein 2).

CARD8_HUMAN
NC score	0.112794 (rank : 43)	θ value	θ > 10 (rank : 75)
Query Neighborhood Hits	66	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y2G2, Q6PGP8, Q96P82	Gene names	CARD8, KIAA0955, NDPP1
Domain Architecture
Description	Caspase recruitment domain-containing protein 8 (Apoptotic protein NDPP1) (DACAR) (CARD-inhibitor of NF-kappa-B-activating ligand) (CARDINAL) (Tumor-up-regulated CARD-containing antagonist of CASP9) (TUCAN).

LRC14_HUMAN
NC score	0.105041 (rank : 44)	θ value	0.0736092 (rank : 32)
Query Neighborhood Hits	66	Target Neighborhood Hits	57	Shared Neighborhood Hits	20
SwissProt Accessions	Q15048	Gene names	LRRC14, KIAA0014
Domain Architecture
Description	Leucine-rich repeat-containing protein 14.

CD14_MOUSE
NC score	0.086027 (rank : 45)	θ value	0.0431538 (rank : 30)
Query Neighborhood Hits	66	Target Neighborhood Hits	104	Shared Neighborhood Hits	14
SwissProt Accessions	P10810	Gene names	Cd14
Domain Architecture
Description	Monocyte differentiation antigen CD14 precursor (Myeloid cell-specific leucine-rich glycoprotein).

MEFV_HUMAN
NC score	0.072425 (rank : 46)	θ value	θ > 10 (rank : 77)
Query Neighborhood Hits	66	Target Neighborhood Hits	431	Shared Neighborhood Hits	11
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

MAPE_HUMAN
NC score	0.055698 (rank : 47)	θ value	θ > 10 (rank : 76)
Query Neighborhood Hits	66	Target Neighborhood Hits	24	Shared Neighborhood Hits	10
SwissProt Accessions	P78395, O43481, Q8IXN8	Gene names	PRAME, MAPE
Domain Architecture	No domain graphic available
Description	Melanoma antigen preferentially expressed in tumors (Preferentially expressed antigen of melanoma) (OPA-interacting protein 4) (OIP4).

TMOD2_HUMAN
NC score	0.054596 (rank : 48)	θ value	4.03905 (rank : 46)
Query Neighborhood Hits	66	Target Neighborhood Hits	29	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NZR1	Gene names	TMOD2, NTMOD
Domain Architecture
Description	Tropomodulin-2 (Neuronal tropomodulin) (N-Tmod).

TMOD4_HUMAN
NC score	0.052461 (rank : 49)	θ value	θ > 10 (rank : 81)
Query Neighborhood Hits	66	Target Neighborhood Hits	37	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NZQ9, Q8WVL3, Q9UKH2	Gene names	TMOD4
Domain Architecture
Description	Tropomodulin-4 (Skeletal muscle tropomodulin) (Sk-Tmod).

TMOD3_MOUSE
NC score	0.049085 (rank : 50)	θ value	6.88961 (rank : 60)
Query Neighborhood Hits	66	Target Neighborhood Hits	34	Shared Neighborhood Hits	18
SwissProt Accessions	Q9JHJ0, Q3TIT1	Gene names	Tmod3
Domain Architecture
Description	Tropomodulin-3 (Ubiquitous tropomodulin) (U-Tmod).

TMOD2_MOUSE
NC score	0.047629 (rank : 51)	θ value	3.0926 (rank : 45)
Query Neighborhood Hits	66	Target Neighborhood Hits	41	Shared Neighborhood Hits	15
SwissProt Accessions	Q9JKK7, Q9JLH9	Gene names	Tmod2
Domain Architecture
Description	Tropomodulin-2 (Neuronal tropomodulin) (N-Tmod).

TMOD1_MOUSE
NC score	0.042653 (rank : 52)	θ value	6.88961 (rank : 59)
Query Neighborhood Hits	66	Target Neighborhood Hits	28	Shared Neighborhood Hits	15
SwissProt Accessions	P49813, Q9ERR9	Gene names	Tmod1, Tmod
Domain Architecture
Description	Tropomodulin-1 (Erythrocyte tropomodulin) (E-Tmod).

TMOD1_HUMAN
NC score	0.041135 (rank : 53)	θ value	8.99809 (rank : 66)
Query Neighborhood Hits	66	Target Neighborhood Hits	32	Shared Neighborhood Hits	15
SwissProt Accessions	P28289, Q9BUF1	Gene names	TMOD1, TMOD
Domain Architecture
Description	Tropomodulin-1 (Erythrocyte tropomodulin) (E-Tmod).

PHLPP_HUMAN
NC score	0.030302 (rank : 54)	θ value	5.27518 (rank : 49)
Query Neighborhood Hits	66	Target Neighborhood Hits	604	Shared Neighborhood Hits	24
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

PHLPL_HUMAN
NC score	0.028087 (rank : 55)	θ value	1.81305 (rank : 40)
Query Neighborhood Hits	66	Target Neighborhood Hits	310	Shared Neighborhood Hits	23
SwissProt Accessions	Q6ZVD8, Q9NV17, Q9Y2E3	Gene names	PHLPPL, KIAA0931
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat protein phosphatase-like (EC 3.1.3.16).

PHLPL_MOUSE
NC score	0.025291 (rank : 56)	θ value	8.99809 (rank : 64)
Query Neighborhood Hits	66	Target Neighborhood Hits	303	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BXA7, Q8BX96	Gene names	Phlppl
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat protein phosphatase-like (EC 3.1.3.16).

LRC33_MOUSE
NC score	0.023447 (rank : 57)	θ value	6.88961 (rank : 56)
Query Neighborhood Hits	66	Target Neighborhood Hits	296	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BMT4, Q3TIA8, Q8BTT4, Q8BUI7, Q8BY16, Q8R063	Gene names	Lrrc33
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 33 precursor.

LRC15_HUMAN
NC score	0.023432 (rank : 58)	θ value	0.125558 (rank : 33)
Query Neighborhood Hits	66	Target Neighborhood Hits	305	Shared Neighborhood Hits	21
SwissProt Accessions	Q8TF66, Q7RTN7	Gene names	LRRC15, LIB
Domain Architecture
Description	Leucine-rich repeat-containing protein 15 precursor (hLib).

LRC15_MOUSE
NC score	0.021262 (rank : 59)	θ value	8.99809 (rank : 62)
Query Neighborhood Hits	66	Target Neighborhood Hits	305	Shared Neighborhood Hits	23
SwissProt Accessions	Q80X72	Gene names	Lrrc15
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 15 precursor.

IL6RA_HUMAN
NC score	0.021161 (rank : 60)	θ value	0.47712 (rank : 35)
Query Neighborhood Hits	66	Target Neighborhood Hits	96	Shared Neighborhood Hits	2
SwissProt Accessions	P08887, Q16202, Q53EQ7, Q5FWG2, Q5VZ23	Gene names	IL6R
Domain Architecture
Description	Interleukin-6 receptor alpha chain precursor (IL-6R-alpha) (IL-6R 1) (Membrane glycoprotein 80) (gp80) (CD126 antigen).

LGR5_HUMAN
NC score	0.020132 (rank : 61)	θ value	1.06291 (rank : 36)
Query Neighborhood Hits	66	Target Neighborhood Hits	452	Shared Neighborhood Hits	23
SwissProt Accessions	O75473, Q9UP75	Gene names	LGR5, GPR49, GPR67
Domain Architecture
Description	Leucine-rich repeat-containing G-protein coupled receptor 5 precursor (Orphan G-protein coupled receptor HG38) (G-protein coupled receptor 49) (G-protein coupled receptor 67).

LRC40_HUMAN
NC score	0.019344 (rank : 62)	θ value	1.38821 (rank : 37)
Query Neighborhood Hits	66	Target Neighborhood Hits	313	Shared Neighborhood Hits	22
SwissProt Accessions	Q9H9A6, Q9BTR7, Q9NSK1, Q9NXC1	Gene names	LRRC40
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 40.

LGR5_MOUSE
NC score	0.018960 (rank : 63)	θ value	0.279714 (rank : 34)
Query Neighborhood Hits	66	Target Neighborhood Hits	484	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Z1P4	Gene names	Lgr5, Fex, Gpr49
Domain Architecture
Description	Leucine-rich repeat-containing G-protein coupled receptor 5 precursor (G-protein coupled receptor 49) (Orphan G-protein coupled receptor FEX).

NU133_MOUSE
NC score	0.018509 (rank : 64)	θ value	1.38821 (rank : 38)
Query Neighborhood Hits	66	Target Neighborhood Hits	34	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R0G9	Gene names	Nup133
Domain Architecture
Description	Nuclear pore complex protein Nup133 (Nucleoporin Nup133) (133 kDa nucleoporin).

LRC8A_MOUSE
NC score	0.017445 (rank : 65)	θ value	2.36792 (rank : 43)
Query Neighborhood Hits	66	Target Neighborhood Hits	274	Shared Neighborhood Hits	22
SwissProt Accessions	Q80WG5	Gene names	Lrrc8a, Lrrc8
Domain Architecture
Description	Leucine-rich repeat-containing protein 8A.

LRC8A_HUMAN
NC score	0.017000 (rank : 66)	θ value	5.27518 (rank : 48)
Query Neighborhood Hits	66	Target Neighborhood Hits	274	Shared Neighborhood Hits	22
SwissProt Accessions	Q8IWT6, Q6UXM2, Q8NCI0, Q9P2B1	Gene names	LRRC8A, KIAA1437, LRRC8
Domain Architecture
Description	Leucine-rich repeat-containing protein 8A.

MCM3A_HUMAN
NC score	0.016014 (rank : 67)	θ value	1.81305 (rank : 39)
Query Neighborhood Hits	66	Target Neighborhood Hits	86	Shared Neighborhood Hits	2
SwissProt Accessions	O60318, Q9UMT4	Gene names	MCM3AP, GANP, KIAA0572, MAP80
Domain Architecture
Description	80 kDa MCM3-associated protein (GANP protein).

LRC32_HUMAN
NC score	0.015956 (rank : 68)	θ value	6.88961 (rank : 55)
Query Neighborhood Hits	66	Target Neighborhood Hits	303	Shared Neighborhood Hits	21
SwissProt Accessions	Q14392, Q86V06	Gene names	LRRC32, GARP
Domain Architecture
Description	Leucine-rich repeat-containing protein 32 precursor (GARP protein) (Garpin) (Glycoprotein A repetitions predominant).

ORC4_MOUSE
NC score	0.015554 (rank : 69)	θ value	3.0926 (rank : 44)
Query Neighborhood Hits	66	Target Neighborhood Hits	34	Shared Neighborhood Hits	2
SwissProt Accessions	O88708, Q9QYX1	Gene names	Orc4l, Orc4
Domain Architecture
Description	Origin recognition complex subunit 4.

LRCH3_MOUSE
NC score	0.014708 (rank : 70)	θ value	6.88961 (rank : 58)
Query Neighborhood Hits	66	Target Neighborhood Hits	257	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BVU0, Q3U222, Q3UZ74	Gene names	Lrch3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and calponin homology domain-containing protein 3 precursor.

LRCH3_HUMAN
NC score	0.012942 (rank : 71)	θ value	6.88961 (rank : 57)
Query Neighborhood Hits	66	Target Neighborhood Hits	270	Shared Neighborhood Hits	17
SwissProt Accessions	Q96II8, Q96FP9, Q9NT52	Gene names	LRCH3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and calponin homology domain-containing protein 3 precursor.

CF072_HUMAN
NC score	0.011231 (rank : 72)	θ value	6.88961 (rank : 52)
Query Neighborhood Hits	66	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NU53	Gene names	C6orf72
Domain Architecture	No domain graphic available
Description	Protein C6orf72 precursor.

LRTM2_HUMAN
NC score	0.010126 (rank : 73)	θ value	8.99809 (rank : 63)
Query Neighborhood Hits	66	Target Neighborhood Hits	282	Shared Neighborhood Hits	20
SwissProt Accessions	O43300, Q7L770	Gene names	LRRTM2, KIAA0416, LRRN2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat transmembrane neuronal protein 2 precursor (Leucine-rich repeat neuronal 2 protein).

GCN1L_HUMAN
NC score	0.009881 (rank : 74)	θ value	6.88961 (rank : 54)
Query Neighborhood Hits	66	Target Neighborhood Hits	112	Shared Neighborhood Hits	2
SwissProt Accessions	Q92616, O95001, O95651, Q6P2S3, Q86X65, Q8N5I5, Q8WU80, Q99736, Q9UE60	Gene names	GCN1L1, KIAA0219
Domain Architecture	No domain graphic available
Description	GCN1-like protein 1 (HsGCN1).

U520_HUMAN
NC score	0.007470 (rank : 75)	θ value	6.88961 (rank : 61)
Query Neighborhood Hits	66	Target Neighborhood Hits	88	Shared Neighborhood Hits	2
SwissProt Accessions	O75643, O94884, Q6PX59, Q96IF2, Q9H7S0	Gene names	ASCC3L1, HELIC2, KIAA0788
Domain Architecture	No domain graphic available
Description	U5 small nuclear ribonucleoprotein 200 kDa helicase (EC 3.6.1.-) (U5 snRNP-specific 200 kDa protein) (U5-200KD) (Activating signal cointegrator 1 complex subunit 3-like 1) (BRR2 homolog).

ABCAD_HUMAN
NC score	0.007031 (rank : 76)	θ value	2.36792 (rank : 41)
Query Neighborhood Hits	66	Target Neighborhood Hits	207	Shared Neighborhood Hits	4
SwissProt Accessions	Q86UQ4, Q6ZTT7, Q86WI2, Q8N248	Gene names	ABCA13
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 13.

ABCAC_HUMAN
NC score	0.004975 (rank : 77)	θ value	6.88961 (rank : 51)
Query Neighborhood Hits	66	Target Neighborhood Hits	123	Shared Neighborhood Hits	3
SwissProt Accessions	Q86UK0, Q8IZW6, Q96JT3, Q9Y4M5	Gene names	ABCA12, ABC12
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 12 (ATP-binding cassette transporter 12) (ATP-binding cassette 12).

ETBR2_MOUSE
NC score	0.003256 (rank : 78)	θ value	5.27518 (rank : 47)
Query Neighborhood Hits	66	Target Neighborhood Hits	487	Shared Neighborhood Hits	3
SwissProt Accessions	Q99JG2, O88313, Q80UB9, Q99JG1	Gene names	Gpr37l1, Etbrlp2
Domain Architecture	No domain graphic available
Description	Endothelin B receptor-like protein 2 precursor (ETBR-LP-2) (G-protein coupled receptor 37-like 1).

PLCB4_HUMAN
NC score	0.003124 (rank : 79)	θ value	8.99809 (rank : 65)
Query Neighborhood Hits	66	Target Neighborhood Hits	658	Shared Neighborhood Hits	4
SwissProt Accessions	Q15147, Q5JYS8, Q5JYT0, Q5JYT4, Q9BQW5, Q9BQW6, Q9BQW8, Q9UJQ2	Gene names	PLCB4
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 4 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-4) (PLC-beta-4).

ETBR2_HUMAN
NC score	0.002839 (rank : 80)	θ value	6.88961 (rank : 53)
Query Neighborhood Hits	66	Target Neighborhood Hits	489	Shared Neighborhood Hits	3
SwissProt Accessions	O60883, Q86VP7	Gene names	GPR37L1, ETBRLP2
Domain Architecture
Description	Endothelin B receptor-like protein 2 precursor (ETBR-LP-2) (G-protein coupled receptor 37-like 1).

PTN22_HUMAN
NC score	0.002621 (rank : 81)	θ value	5.27518 (rank : 50)
Query Neighborhood Hits	66	Target Neighborhood Hits	109	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y2R2, O95063, O95064	Gene names	PTPN22, PTPN8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP) (Lymphoid phosphatase) (LyP).