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Network neighborhood for query Sequence : BIRC1_HUMAN

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BIRC1_HUMAN
SwissProt Accessions	Q13075, O75857, Q13730, Q99796	Gene names	BIRC1, NAIP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1 (Neuronal apoptosis inhibitory protein).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

BIR1A_MOUSE
θ value	0 (rank : 1)	NC score	0.992756 (rank : 2)
Query Neighborhood Hits	61	Target Neighborhood Hits	94	Shared Neighborhood Hits	41
SwissProt Accessions	Q9QWK5, Q9JIB5, Q9R017	Gene names	Birc1a, Naip, Naip1
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1a (Neuronal apoptosis inhibitory protein 1).

BIR1B_MOUSE
θ value	0 (rank : 2)	NC score	0.992583 (rank : 3)
Query Neighborhood Hits	61	Target Neighborhood Hits	93	Shared Neighborhood Hits	44
SwissProt Accessions	Q9QUK4, O09124, Q9R030	Gene names	Birc1b, Naip-rs6, Naip2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1b (Neuronal apoptosis inhibitory protein 2).

BIR1E_MOUSE
θ value	0 (rank : 3)	NC score	0.991890 (rank : 5)
Query Neighborhood Hits	61	Target Neighborhood Hits	93	Shared Neighborhood Hits	41
SwissProt Accessions	Q9R016, O09121, O09122, P81703, Q9R029	Gene names	Birc1e, Naip-rs3, Naip5
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1e (Neuronal apoptosis inhibitory protein 5).

BIR1F_MOUSE
θ value	0 (rank : 4)	NC score	0.992325 (rank : 4)
Query Neighborhood Hits	61	Target Neighborhood Hits	88	Shared Neighborhood Hits	42
SwissProt Accessions	Q9JIB6, O09121, O09122, P81704	Gene names	Birc1f, Naip-rs4, Naip6
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1f (Neuronal apoptosis inhibitory protein 6).

BIR1G_MOUSE
θ value	0 (rank : 5)	NC score	0.991761 (rank : 6)
Query Neighborhood Hits	61	Target Neighborhood Hits	92	Shared Neighborhood Hits	41
SwissProt Accessions	Q9JIB3	Gene names	Birc1g, Naip7
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1g (Neuronal apoptosis inhibitory protein 7).

BIRC1_HUMAN
θ value	0 (rank : 6)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	61	Target Neighborhood Hits	61	Shared Neighborhood Hits	61
SwissProt Accessions	Q13075, O75857, Q13730, Q99796	Gene names	BIRC1, NAIP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1 (Neuronal apoptosis inhibitory protein).

CAR12_HUMAN
θ value	7.25919e-50 (rank : 7)	NC score	0.761701 (rank : 7)
Query Neighborhood Hits	61	Target Neighborhood Hits	132	Shared Neighborhood Hits	35
SwissProt Accessions	Q9NPP4, Q96J81, Q96J82, Q96J83	Gene names	CARD12, CLAN, CLAN1
Domain Architecture
Description	Caspase recruitment domain-containing protein 12 (Ice protease- activating factor) (Ipaf) (CARD, LRR, and NACHT-containing protein) (Clan protein).

BIRC2_HUMAN
θ value	5.76516e-39 (rank : 8)	NC score	0.713640 (rank : 10)
Query Neighborhood Hits	61	Target Neighborhood Hits	142	Shared Neighborhood Hits	20
SwissProt Accessions	Q13490, Q16516, Q4TTG0	Gene names	BIRC2, API1, IAP2, MIHB
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (HIAP2) (HIAP-2) (C-IAP1) (TNFR2-TRAF signaling complex protein 2) (IAP homolog B).

BIRC2_MOUSE
θ value	9.83387e-39 (rank : 9)	NC score	0.709813 (rank : 11)
Query Neighborhood Hits	61	Target Neighborhood Hits	137	Shared Neighborhood Hits	21
SwissProt Accessions	Q62210, O08864	Gene names	Birc2, Birc3, Iap2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (MIAP2) (MIAP-2).

BIRC3_HUMAN
θ value	1.20211e-36 (rank : 10)	NC score	0.706491 (rank : 12)
Query Neighborhood Hits	61	Target Neighborhood Hits	133	Shared Neighborhood Hits	18
SwissProt Accessions	Q13489, Q16628, Q9HC27, Q9UP46	Gene names	BIRC3, API2, IAP1, MIHC
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (HIAP1) (HIAP-1) (C-IAP2) (TNFR2-TRAF signaling complex protein 1) (IAP homolog C) (Apoptosis inhibitor 2) (API2).

BIRC4_MOUSE
θ value	1.20211e-36 (rank : 11)	NC score	0.728339 (rank : 8)
Query Neighborhood Hits	61	Target Neighborhood Hits	89	Shared Neighborhood Hits	17
SwissProt Accessions	Q60989, O08865	Gene names	Birc4, Aipa, Api3, Miha, Xiap
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 4 (Inhibitor of apoptosis protein 3) (X-linked inhibitor of apoptosis protein) (X-linked IAP) (IAP homolog A) (MIAP3) (MIAP-3).

BIRC3_MOUSE
θ value	2.67802e-36 (rank : 12)	NC score	0.703636 (rank : 13)
Query Neighborhood Hits	61	Target Neighborhood Hits	113	Shared Neighborhood Hits	17
SwissProt Accessions	O08863	Gene names	Birc3, Birc2, Iap1
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (MIAP1) (MIAP-1).

BIRC4_HUMAN
θ value	3.61944e-33 (rank : 13)	NC score	0.721752 (rank : 9)
Query Neighborhood Hits	61	Target Neighborhood Hits	89	Shared Neighborhood Hits	17
SwissProt Accessions	P98170, Q9NQ14	Gene names	BIRC4, API3, IAP3, XIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 4 (Inhibitor of apoptosis protein 3) (X-linked inhibitor of apoptosis protein) (X-linked IAP) (IAP-like protein) (HILP).

BIRC7_HUMAN
θ value	2.97466e-19 (rank : 14)	NC score	0.629515 (rank : 17)
Query Neighborhood Hits	61	Target Neighborhood Hits	185	Shared Neighborhood Hits	17
SwissProt Accessions	Q96CA5, Q9BQV0, Q9H2A8, Q9HAP7	Gene names	BIRC7, KIAP, LIVIN, MLIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 7 (Kidney inhibitor of apoptosis protein) (KIAP) (Melanoma inhibitor of apoptosis protein) (ML-IAP) (Livin).

BIRC8_HUMAN
θ value	1.99529e-15 (rank : 15)	NC score	0.635489 (rank : 14)
Query Neighborhood Hits	61	Target Neighborhood Hits	121	Shared Neighborhood Hits	17
SwissProt Accessions	Q96P09, Q96RW5	Gene names	BIRC8, ILP2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 8 (Inhibitor of apoptosis- like protein 2) (IAP-like protein 2) (ILP-2) (Testis-specific inhibitor of apoptosis).

BIRC5_MOUSE
θ value	2.52405e-10 (rank : 16)	NC score	0.633501 (rank : 15)
Query Neighborhood Hits	61	Target Neighborhood Hits	19	Shared Neighborhood Hits	17
SwissProt Accessions	O70201, Q923F7, Q9WU53, Q9WU54	Gene names	Birc5, Api4, Iap4
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 5 (Apoptosis inhibitor survivin) (Apoptosis inhibitor 4) (TIAP).

BIRC5_HUMAN
θ value	1.63604e-09 (rank : 17)	NC score	0.629823 (rank : 16)
Query Neighborhood Hits	61	Target Neighborhood Hits	20	Shared Neighborhood Hits	17
SwissProt Accessions	O15392, Q2I3N8, Q4VGX0, Q53F61, Q5MGC6, Q6FHL2, Q75SP2, Q9P2W8	Gene names	BIRC5, API4, IAP4
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 5 (Apoptosis inhibitor survivin) (Apoptosis inhibitor 4).

NALP2_HUMAN
θ value	2.79066e-09 (rank : 18)	NC score	0.291805 (rank : 23)
Query Neighborhood Hits	61	Target Neighborhood Hits	65	Shared Neighborhood Hits	29
SwissProt Accessions	Q9NX02, Q53FL5, Q59G09, Q8IXT0, Q9BVN5, Q9H6G6, Q9HAV9, Q9NWK3	Gene names	NALP2, NBS1, PAN1, PYPAF2
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 2 (PYRIN domain and NACHT domain-containing protein 1) (PYRIN-containing APAF1-like protein 2) (Nucleotide-binding site protein 1).

NALP1_HUMAN
θ value	3.08544e-08 (rank : 19)	NC score	0.297279 (rank : 22)
Query Neighborhood Hits	61	Target Neighborhood Hits	138	Shared Neighborhood Hits	29
SwissProt Accessions	Q9C000, Q9BZZ8, Q9BZZ9, Q9HAV8, Q9UFT4, Q9Y2E0	Gene names	NALP1, CARD7, DEFCAP, KIAA0926, NAC
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 1 (Death effector filament- forming ced-4-like apoptosis protein) (Nucleotide-binding domain and caspase recruitment domain) (Caspase recruitment domain protein 7).

NALP4_HUMAN
θ value	1.99992e-07 (rank : 20)	NC score	0.268038 (rank : 28)
Query Neighborhood Hits	61	Target Neighborhood Hits	81	Shared Neighborhood Hits	29
SwissProt Accessions	Q96MN2, Q86W87, Q96AY6	Gene names	NALP4, PAN2, PYPAF4, RNH2
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 4 (PYRIN-containing APAF1-like protein 4) (PAAD and NACHT-containing protein 2) (PYRIN and NACHT- containing protein 2) (Ribonuclease inhibitor 2).

BIRC6_HUMAN
θ value	7.59969e-07 (rank : 21)	NC score	0.331518 (rank : 19)
Query Neighborhood Hits	61	Target Neighborhood Hits	161	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NR09, Q9ULD1	Gene names	BIRC6, KIAA1289
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 6 (Ubiquitin-conjugating BIR-domain enzyme apollon).

NAL12_HUMAN
θ value	1.29631e-06 (rank : 22)	NC score	0.254762 (rank : 30)
Query Neighborhood Hits	61	Target Neighborhood Hits	96	Shared Neighborhood Hits	30
SwissProt Accessions	P59046, Q8NEU4, Q9BY26	Gene names	NALP12, PYPAF7, RNO
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 12 (PYRIN-containing APAF1-like protein 7) (Monarch-1) (Regulated by nitric oxide).

NALP7_HUMAN
θ value	1.29631e-06 (rank : 23)	NC score	0.279722 (rank : 25)
Query Neighborhood Hits	61	Target Neighborhood Hits	65	Shared Neighborhood Hits	31
SwissProt Accessions	Q8WX94, Q7RTR1	Gene names	NALP7, NOD12, PYPAF3
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 7 (PYRIN-containing APAF1-like protein 3).

NAL10_MOUSE
θ value	3.77169e-06 (rank : 24)	NC score	0.312183 (rank : 20)
Query Neighborhood Hits	61	Target Neighborhood Hits	46	Shared Neighborhood Hits	28
SwissProt Accessions	Q8CCN1	Gene names	Nalp10, Pynod
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 10.

CAR15_MOUSE
θ value	3.19293e-05 (rank : 25)	NC score	0.298380 (rank : 21)
Query Neighborhood Hits	61	Target Neighborhood Hits	93	Shared Neighborhood Hits	29
SwissProt Accessions	Q8K3Z0	Gene names	Card15, Nod2
Domain Architecture
Description	Caspase recruitment domain-containing protein 15 (Protein Nod2).

CIAS1_MOUSE
θ value	3.19293e-05 (rank : 26)	NC score	0.215998 (rank : 34)
Query Neighborhood Hits	61	Target Neighborhood Hits	67	Shared Neighborhood Hits	29
SwissProt Accessions	Q8R4B8, Q6JEL0	Gene names	Cias1, Mmig1, Nalp3, Pypaf1
Domain Architecture
Description	Cold autoinflammatory syndrome 1 protein homolog (PYRIN-containing APAF1-like protein 1) (Mast cell maturation-associated-inducible protein 1) (Cryopyrin).

CIAS1_HUMAN
θ value	9.29e-05 (rank : 27)	NC score	0.236951 (rank : 33)
Query Neighborhood Hits	61	Target Neighborhood Hits	76	Shared Neighborhood Hits	29
SwissProt Accessions	Q96P20, O75434, Q59H68, Q5JQS8, Q5JQS9, Q6TG35, Q8TCW0, Q8TEU9, Q8WXH9	Gene names	CIAS1, NALP3, PYPAF1
Domain Architecture
Description	Cold autoinflammatory syndrome 1 protein (Cryopyrin) (NACHT-, LRR- and PYD-containing protein 3) (PYRIN-containing APAF1-like protein 1) (Angiotensin/vasopressin receptor AII/AVP-like).

NAL10_HUMAN
θ value	0.000121331 (rank : 28)	NC score	0.286000 (rank : 24)
Query Neighborhood Hits	61	Target Neighborhood Hits	55	Shared Neighborhood Hits	28
SwissProt Accessions	Q86W26, Q6JGT0	Gene names	NALP10, NOD8, PYNOD
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 10 (Nucleotide-binding oligomerization domain protein 8).

NAL13_HUMAN
θ value	0.000121331 (rank : 29)	NC score	0.277725 (rank : 26)
Query Neighborhood Hits	61	Target Neighborhood Hits	93	Shared Neighborhood Hits	33
SwissProt Accessions	Q86W25, Q7RTR5	Gene names	NALP13, NOD14
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 13 (Nucleotide-binding oligomerization domain protein 14).

NAL14_HUMAN
θ value	0.00020696 (rank : 30)	NC score	0.242507 (rank : 32)
Query Neighborhood Hits	61	Target Neighborhood Hits	76	Shared Neighborhood Hits	31
SwissProt Accessions	Q86W24, Q7RTR6	Gene names	NALP14, NOD5
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 14 (Nucleotide-binding oligomerization domain protein 5).

LRC31_HUMAN
θ value	0.000270298 (rank : 31)	NC score	0.336124 (rank : 18)
Query Neighborhood Hits	61	Target Neighborhood Hits	139	Shared Neighborhood Hits	31
SwissProt Accessions	Q6UY01, Q8N848, Q9H5N5	Gene names	LRRC31
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 31.

NALP6_HUMAN
θ value	0.000602161 (rank : 32)	NC score	0.249306 (rank : 31)
Query Neighborhood Hits	61	Target Neighborhood Hits	52	Shared Neighborhood Hits	28
SwissProt Accessions	P59044	Gene names	NALP6, PYPAF5
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 6 (PYRIN-containing APAF1-like protein 5).

CAR15_HUMAN
θ value	0.00134147 (rank : 33)	NC score	0.269204 (rank : 27)
Query Neighborhood Hits	61	Target Neighborhood Hits	77	Shared Neighborhood Hits	30
SwissProt Accessions	Q9HC29, Q96RH5, Q96RH6, Q96RH8	Gene names	CARD15, IBD1, NOD2
Domain Architecture
Description	Caspase recruitment domain-containing protein 15 (Protein Nod2) (Inflammatory bowel disease protein 1).

NALP6_MOUSE
θ value	0.00509761 (rank : 34)	NC score	0.255729 (rank : 29)
Query Neighborhood Hits	61	Target Neighborhood Hits	55	Shared Neighborhood Hits	28
SwissProt Accessions	Q91WS2, Q8K0L4	Gene names	Nalp6, Pypaf5
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 6 (PYRIN-containing APAF1-like protein 5-like).

C2TA_MOUSE
θ value	0.0252991 (rank : 35)	NC score	0.183230 (rank : 36)
Query Neighborhood Hits	61	Target Neighborhood Hits	131	Shared Neighborhood Hits	30
SwissProt Accessions	P79621, O46787, O78036, O78109, Q31115, Q9TPP1	Gene names	Ciita, C2ta, Mhc2ta
Domain Architecture
Description	MHC class II transactivator (CIITA).

LRC18_MOUSE
θ value	0.0330416 (rank : 36)	NC score	0.047858 (rank : 65)
Query Neighborhood Hits	61	Target Neighborhood Hits	224	Shared Neighborhood Hits	14
SwissProt Accessions	Q9CQ07, Q6P8T8, Q80ZT3, Q9CW01, Q9DA89	Gene names	Lrrc18, Mtlr1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 18 (Testis-specific LRR protein).

LRC8B_MOUSE
θ value	0.0330416 (rank : 37)	NC score	0.022824 (rank : 69)
Query Neighborhood Hits	61	Target Neighborhood Hits	283	Shared Neighborhood Hits	15
SwissProt Accessions	Q5DU41	Gene names	Lrrc8b, Kiaa0231
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 8B.

CARD4_MOUSE
θ value	0.0961366 (rank : 38)	NC score	0.184730 (rank : 35)
Query Neighborhood Hits	61	Target Neighborhood Hits	85	Shared Neighborhood Hits	30
SwissProt Accessions	Q8BHB0, Q8BUT6	Gene names	Card4
Domain Architecture
Description	Caspase recruitment domain-containing protein 4.

NALP5_HUMAN
θ value	0.279714 (rank : 39)	NC score	0.176138 (rank : 37)
Query Neighborhood Hits	61	Target Neighborhood Hits	88	Shared Neighborhood Hits	30
SwissProt Accessions	P59047, Q86W29	Gene names	NALP5, MATER
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Mater protein homolog).

CARD4_HUMAN
θ value	0.62314 (rank : 40)	NC score	0.160692 (rank : 39)
Query Neighborhood Hits	61	Target Neighborhood Hits	102	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y239, Q8IWF5	Gene names	CARD4, NOD1
Domain Architecture
Description	Caspase recruitment domain-containing protein 4 (Protein Nod1).

CEP63_HUMAN
θ value	0.62314 (rank : 41)	NC score	0.005874 (rank : 76)
Query Neighborhood Hits	61	Target Neighborhood Hits	1005	Shared Neighborhood Hits	5
SwissProt Accessions	Q96MT8, Q96CR0, Q9H8F5, Q9H8N0	Gene names	CEP63
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 63 kDa (Cep63 protein).

ANLN_HUMAN
θ value	0.813845 (rank : 42)	NC score	0.018069 (rank : 70)
Query Neighborhood Hits	61	Target Neighborhood Hits	222	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NQW6, Q5CZ78, Q6NSK5, Q9H8Y4, Q9NVN9, Q9NVP0	Gene names	ANLN
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

TRIB1_MOUSE
θ value	1.38821 (rank : 43)	NC score	0.004479 (rank : 77)
Query Neighborhood Hits	61	Target Neighborhood Hits	593	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K4K4, Q8BFS7, Q8BJR9, Q8BZX3, Q91W04	Gene names	Trib1, Trb1
Domain Architecture	No domain graphic available
Description	Tribbles homolog 1 (TRB-1).

LRC39_HUMAN
θ value	1.81305 (rank : 44)	NC score	0.029163 (rank : 68)
Query Neighborhood Hits	61	Target Neighborhood Hits	274	Shared Neighborhood Hits	17
SwissProt Accessions	Q96DD0, Q5VVK7	Gene names	LRRC39
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 39 (Densin hlg).

TLR9_MOUSE
θ value	1.81305 (rank : 45)	NC score	0.035687 (rank : 67)
Query Neighborhood Hits	61	Target Neighborhood Hits	291	Shared Neighborhood Hits	18
SwissProt Accessions	Q9EQU3, Q99MF2, Q99MQ8	Gene names	Tlr9
Domain Architecture
Description	Toll-like receptor 9 precursor (CD289 antigen).

LRC18_HUMAN
θ value	2.36792 (rank : 46)	NC score	0.039788 (rank : 66)
Query Neighborhood Hits	61	Target Neighborhood Hits	217	Shared Neighborhood Hits	13
SwissProt Accessions	Q8N456, Q6UY02	Gene names	LRRC18
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 18.

LRRN1_MOUSE
θ value	2.36792 (rank : 47)	NC score	0.007881 (rank : 73)
Query Neighborhood Hits	61	Target Neighborhood Hits	508	Shared Neighborhood Hits	10
SwissProt Accessions	Q61809, Q3USY1, Q69ZI0	Gene names	Lrrn1, Kiaa1497
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 1 precursor (Neuronal leucine- rich repeat protein 1) (NLRR-1).

TLR13_MOUSE
θ value	2.36792 (rank : 48)	NC score	0.010090 (rank : 71)
Query Neighborhood Hits	61	Target Neighborhood Hits	335	Shared Neighborhood Hits	17
SwissProt Accessions	Q6R5N8, Q3TDS2	Gene names	Tlr13
Domain Architecture	No domain graphic available
Description	Toll-like receptor 13 precursor.

C2TA_HUMAN
θ value	3.0926 (rank : 49)	NC score	0.125016 (rank : 44)
Query Neighborhood Hits	61	Target Neighborhood Hits	190	Shared Neighborhood Hits	26
SwissProt Accessions	P33076	Gene names	CIITA, MHC2TA
Domain Architecture
Description	MHC class II transactivator (CIITA).

TRIB2_HUMAN
θ value	3.0926 (rank : 50)	NC score	0.003111 (rank : 82)
Query Neighborhood Hits	61	Target Neighborhood Hits	657	Shared Neighborhood Hits	5
SwissProt Accessions	Q92519	Gene names	TRIB2, TRB2
Domain Architecture	No domain graphic available
Description	Tribbles homolog 2 (TRB-2).

ARHG6_MOUSE
θ value	4.03905 (rank : 51)	NC score	0.003767 (rank : 80)
Query Neighborhood Hits	61	Target Neighborhood Hits	394	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K4I3, Q8C9V4	Gene names	Arhgef6
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6).

TRIB1_HUMAN
θ value	4.03905 (rank : 52)	NC score	0.003412 (rank : 81)
Query Neighborhood Hits	61	Target Neighborhood Hits	598	Shared Neighborhood Hits	5
SwissProt Accessions	Q96RU8, O15180, Q9H2Y8	Gene names	TRIB1, C8FW, GIG2, TRB1
Domain Architecture	No domain graphic available
Description	Tribbles homolog 1 (TRB-1) (SKIP1) (G-protein-coupled receptor-induced protein 2) (GIG-2).

LRRN1_HUMAN
θ value	5.27518 (rank : 53)	NC score	0.006989 (rank : 75)
Query Neighborhood Hits	61	Target Neighborhood Hits	518	Shared Neighborhood Hits	10
SwissProt Accessions	Q6UXK5, Q3LID5, Q8IYV5, Q9H8V1, Q9P231	Gene names	LRRN1, KIAA1497
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 1 precursor (Neuronal leucine- rich repeat protein 1) (NLRR-1).

NALP5_MOUSE
θ value	5.27518 (rank : 54)	NC score	0.169297 (rank : 38)
Query Neighborhood Hits	61	Target Neighborhood Hits	560	Shared Neighborhood Hits	32
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

TRIB2_MOUSE
θ value	5.27518 (rank : 55)	NC score	0.002665 (rank : 83)
Query Neighborhood Hits	61	Target Neighborhood Hits	653	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K4K3, Q8K017, Q8R2V8	Gene names	Trib2
Domain Architecture	No domain graphic available
Description	Tribbles homolog 2 (TRB-2).

REST_MOUSE
θ value	6.88961 (rank : 56)	NC score	-0.001639 (rank : 85)
Query Neighborhood Hits	61	Target Neighborhood Hits	1506	Shared Neighborhood Hits	5
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

SKP2_MOUSE
θ value	6.88961 (rank : 57)	NC score	0.007388 (rank : 74)
Query Neighborhood Hits	61	Target Neighborhood Hits	69	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z0Z3, Q8BSG7, Q8C8Y9, Q8CB22, Q99J53	Gene names	Skp2
Domain Architecture
Description	S-phase kinase-associated protein 2 (F-box protein Skp2) (Cyclin A/CDK2-associated protein p45) (F-box/WD-40 protein 1) (FWD1).

ZFY27_HUMAN
θ value	6.88961 (rank : 58)	NC score	0.007970 (rank : 72)
Query Neighborhood Hits	61	Target Neighborhood Hits	64	Shared Neighborhood Hits	2
SwissProt Accessions	Q5T4F4, Q5T4F1, Q5T4F2, Q5T4F3, Q8N1K0, Q8N6D6, Q8NCA0, Q8NDE4, Q96M08	Gene names	ZFYVE27
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 27.

PEX6_HUMAN
θ value	8.99809 (rank : 59)	NC score	0.004158 (rank : 79)
Query Neighborhood Hits	61	Target Neighborhood Hits	99	Shared Neighborhood Hits	5
SwissProt Accessions	Q13608, Q8WYQ2, Q99476	Gene names	PEX6, PXAAA1
Domain Architecture
Description	Peroxisome assembly factor 2 (PAF-2) (Peroxisomal-type ATPase 1) (Peroxin-6) (Peroxisomal biogenesis factor 6).

PEX6_MOUSE
θ value	8.99809 (rank : 60)	NC score	0.004169 (rank : 78)
Query Neighborhood Hits	61	Target Neighborhood Hits	94	Shared Neighborhood Hits	5
SwissProt Accessions	Q99LC9, Q6YNQ9	Gene names	Pex6
Domain Architecture	No domain graphic available
Description	Peroxisome assembly factor 2 (PAF-2) (Peroxisomal-type ATPase 1) (Peroxin-6) (Peroxisomal biogenesis factor 6).

RASL2_HUMAN
θ value	8.99809 (rank : 61)	NC score	0.001790 (rank : 84)
Query Neighborhood Hits	61	Target Neighborhood Hits	161	Shared Neighborhood Hits	2
SwissProt Accessions	O43374, O60286, Q86UW3, Q96QU0	Gene names	RASA4, CAPRI, GAPL, KIAA0538
Domain Architecture
Description	Ras GTPase-activating protein 4 (RasGAP-activating-like protein 2) (Calcium-promoted Ras inactivator).

ASC_MOUSE
θ value	θ > 10 (rank : 62)	NC score	0.059139 (rank : 60)
Query Neighborhood Hits	61	Target Neighborhood Hits	17	Shared Neighborhood Hits	11
SwissProt Accessions	Q9EPB4, Q9D2W9	Gene names	Pycard, Asc
Domain Architecture
Description	Apoptosis-associated speck-like protein containing a CARD (mASC) (PYD and CARD domain-containing protein).

CARD8_HUMAN
θ value	θ > 10 (rank : 63)	NC score	0.062626 (rank : 59)
Query Neighborhood Hits	61	Target Neighborhood Hits	22	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y2G2, Q6PGP8, Q96P82	Gene names	CARD8, KIAA0955, NDPP1
Domain Architecture
Description	Caspase recruitment domain-containing protein 8 (Apoptotic protein NDPP1) (DACAR) (CARD-inhibitor of NF-kappa-B-activating ligand) (CARDINAL) (Tumor-up-regulated CARD-containing antagonist of CASP9) (TUCAN).

CF154_HUMAN
θ value	θ > 10 (rank : 64)	NC score	0.068149 (rank : 56)
Query Neighborhood Hits	61	Target Neighborhood Hits	36	Shared Neighborhood Hits	18
SwissProt Accessions	Q5JTD7	Gene names	C6orf154
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf154.

CGRF1_HUMAN
θ value	θ > 10 (rank : 65)	NC score	0.078956 (rank : 52)
Query Neighborhood Hits	61	Target Neighborhood Hits	51	Shared Neighborhood Hits	8
SwissProt Accessions	Q99675, Q96BX2	Gene names	CGRRF1, CGR19
Domain Architecture	No domain graphic available
Description	Cell growth regulator with RING finger domain 1 (Cell growth regulatory gene 19 protein).

CGRF1_MOUSE
θ value	θ > 10 (rank : 66)	NC score	0.076999 (rank : 53)
Query Neighborhood Hits	61	Target Neighborhood Hits	47	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BMJ7, Q3U3F1, Q8CI24	Gene names	Cgrrf1, Cgr19
Domain Architecture	No domain graphic available
Description	Cell growth regulator with RING finger domain 1 (Cell growth regulatory gene 19 protein).

LRC34_HUMAN
θ value	θ > 10 (rank : 67)	NC score	0.083825 (rank : 50)
Query Neighborhood Hits	61	Target Neighborhood Hits	67	Shared Neighborhood Hits	21
SwissProt Accessions	Q8IZ02	Gene names	LRRC34
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 34.

LRC34_MOUSE
θ value	θ > 10 (rank : 68)	NC score	0.076063 (rank : 54)
Query Neighborhood Hits	61	Target Neighborhood Hits	58	Shared Neighborhood Hits	19
SwissProt Accessions	Q9DAM1	Gene names	Lrrc34
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 34.

LRSM1_MOUSE
θ value	θ > 10 (rank : 69)	NC score	0.058263 (rank : 61)
Query Neighborhood Hits	61	Target Neighborhood Hits	874	Shared Neighborhood Hits	18
SwissProt Accessions	Q80ZI6	Gene names	Lrsam1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase).

MGRN1_MOUSE
θ value	θ > 10 (rank : 70)	NC score	0.051300 (rank : 63)
Query Neighborhood Hits	61	Target Neighborhood Hits	149	Shared Neighborhood Hits	8
SwissProt Accessions	Q9D074, Q3U5V9, Q3UDA1, Q6ZQ97, Q8BZM9	Gene names	Mgrn1, Kiaa0544
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1).

MYLIP_HUMAN
θ value	θ > 10 (rank : 71)	NC score	0.083342 (rank : 51)
Query Neighborhood Hits	61	Target Neighborhood Hits	162	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WY64, Q9BU73, Q9NRL9, Q9UHE7	Gene names	MYLIP, BZF1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

MYLIP_MOUSE
θ value	θ > 10 (rank : 72)	NC score	0.069055 (rank : 55)
Query Neighborhood Hits	61	Target Neighborhood Hits	139	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BM54, Q3TX01, Q8BLY9, Q91Z47	Gene names	Mylip
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

NAL11_HUMAN
θ value	θ > 10 (rank : 73)	NC score	0.157155 (rank : 40)
Query Neighborhood Hits	61	Target Neighborhood Hits	66	Shared Neighborhood Hits	23
SwissProt Accessions	P59045, Q53ZZ0, Q8NBF5	Gene names	NALP11, NOD17, PYPAF6
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 11 (PYRIN-containing APAF1-like protein 6) (Nucleotide-binding oligomerization domain protein 17).

NEUL1_HUMAN
θ value	θ > 10 (rank : 74)	NC score	0.063827 (rank : 58)
Query Neighborhood Hits	61	Target Neighborhood Hits	114	Shared Neighborhood Hits	8
SwissProt Accessions	O76050, Q5TDR2, Q5TDR3, Q8TAN0, Q9H463	Gene names	NEURL, NEURL1, RNF67
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (h-neuralized 1) (h-neu) (RING finger protein 67).

NEURL_MOUSE
θ value	θ > 10 (rank : 75)	NC score	0.066032 (rank : 57)
Query Neighborhood Hits	61	Target Neighborhood Hits	106	Shared Neighborhood Hits	8
SwissProt Accessions	Q923S6, Q91ZT6, Q9CWF1, Q9QWF1	Gene names	Neurl, Neurl1
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (m-neuralized 1) (m-neu1).

RFFL_HUMAN
θ value	θ > 10 (rank : 76)	NC score	0.113645 (rank : 47)
Query Neighborhood Hits	61	Target Neighborhood Hits	175	Shared Neighborhood Hits	9
SwissProt Accessions	Q8WZ73, Q8NHW0, Q8TBY7, Q96BE6	Gene names	RFFL, RNF189, RNF34L
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (FYVE-RING finger protein Sakura) (Fring) (Caspases-8 and -10- associated RING finger protein 2) (CARP-2) (Caspase regulator CARP2) (RING finger protein 189) (RING finger protein 34-like).

RFFL_MOUSE
θ value	θ > 10 (rank : 77)	NC score	0.115594 (rank : 45)
Query Neighborhood Hits	61	Target Neighborhood Hits	145	Shared Neighborhood Hits	9
SwissProt Accessions	Q6ZQM0, Q5SVC2, Q5SVC4, Q9D543, Q9D9B1	Gene names	Rffl
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (Fring).

RGP1_HUMAN
θ value	θ > 10 (rank : 78)	NC score	0.051860 (rank : 62)
Query Neighborhood Hits	61	Target Neighborhood Hits	124	Shared Neighborhood Hits	17
SwissProt Accessions	P46060	Gene names	RANGAP1
Domain Architecture
Description	Ran GTPase-activating protein 1.

RGP1_MOUSE
θ value	θ > 10 (rank : 79)	NC score	0.050980 (rank : 64)
Query Neighborhood Hits	61	Target Neighborhood Hits	105	Shared Neighborhood Hits	17
SwissProt Accessions	P46061, Q60801	Gene names	Rangap1, Fug1
Domain Architecture
Description	Ran GTPase-activating protein 1.

RINI_HUMAN
θ value	θ > 10 (rank : 80)	NC score	0.140639 (rank : 41)
Query Neighborhood Hits	61	Target Neighborhood Hits	78	Shared Neighborhood Hits	21
SwissProt Accessions	P13489	Gene names	RNH1, PRI, RNH
Domain Architecture
Description	Ribonuclease inhibitor (Ribonuclease/angiogenin inhibitor 1) (RAI) (Placental ribonuclease inhibitor) (RNase inhibitor) (RI).

RINI_MOUSE
θ value	θ > 10 (rank : 81)	NC score	0.137478 (rank : 42)
Query Neighborhood Hits	61	Target Neighborhood Hits	87	Shared Neighborhood Hits	22
SwissProt Accessions	Q91VI7, Q924P4	Gene names	Rnh1, Rnh
Domain Architecture	No domain graphic available
Description	Ribonuclease inhibitor (Ribonuclease/angiogenin inhibitor 1).

RKHD1_HUMAN
θ value	θ > 10 (rank : 82)	NC score	0.086911 (rank : 49)
Query Neighborhood Hits	61	Target Neighborhood Hits	163	Shared Neighborhood Hits	8
SwissProt Accessions	Q86XN8	Gene names	RKHD1, KIAA2031
Domain Architecture
Description	RING finger and KH domain-containing protein 1.

RNF26_HUMAN
θ value	θ > 10 (rank : 83)	NC score	0.128284 (rank : 43)
Query Neighborhood Hits	61	Target Neighborhood Hits	95	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BY78	Gene names	RNF26
Domain Architecture	No domain graphic available
Description	RING finger protein 26.

RNF34_HUMAN
θ value	θ > 10 (rank : 84)	NC score	0.113492 (rank : 48)
Query Neighborhood Hits	61	Target Neighborhood Hits	153	Shared Neighborhood Hits	9
SwissProt Accessions	Q969K3, Q8NG47, Q9H6W8	Gene names	RNF34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (FYVE-RING finger protein Momo) (Human RING finger homologous to inhibitor of apoptosis protein) (hRFI) (Caspases-8 and -10-associated RING finger protein 1) (CARP-1) (Caspase regulator CARP1).

RNF34_MOUSE
θ value	θ > 10 (rank : 85)	NC score	0.114039 (rank : 46)
Query Neighborhood Hits	61	Target Neighborhood Hits	160	Shared Neighborhood Hits	9
SwissProt Accessions	Q99KR6, Q3UV45	Gene names	Rnf34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (Phafin-1).

Hits sorted by NC score

BIRC1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 6)
Query Neighborhood Hits	61	Target Neighborhood Hits	61	Shared Neighborhood Hits	61
SwissProt Accessions	Q13075, O75857, Q13730, Q99796	Gene names	BIRC1, NAIP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1 (Neuronal apoptosis inhibitory protein).

BIR1A_MOUSE
NC score	0.992756 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	61	Target Neighborhood Hits	94	Shared Neighborhood Hits	41
SwissProt Accessions	Q9QWK5, Q9JIB5, Q9R017	Gene names	Birc1a, Naip, Naip1
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1a (Neuronal apoptosis inhibitory protein 1).

BIR1B_MOUSE
NC score	0.992583 (rank : 3)	θ value	0 (rank : 2)
Query Neighborhood Hits	61	Target Neighborhood Hits	93	Shared Neighborhood Hits	44
SwissProt Accessions	Q9QUK4, O09124, Q9R030	Gene names	Birc1b, Naip-rs6, Naip2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1b (Neuronal apoptosis inhibitory protein 2).

BIR1F_MOUSE
NC score	0.992325 (rank : 4)	θ value	0 (rank : 4)
Query Neighborhood Hits	61	Target Neighborhood Hits	88	Shared Neighborhood Hits	42
SwissProt Accessions	Q9JIB6, O09121, O09122, P81704	Gene names	Birc1f, Naip-rs4, Naip6
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1f (Neuronal apoptosis inhibitory protein 6).

BIR1E_MOUSE
NC score	0.991890 (rank : 5)	θ value	0 (rank : 3)
Query Neighborhood Hits	61	Target Neighborhood Hits	93	Shared Neighborhood Hits	41
SwissProt Accessions	Q9R016, O09121, O09122, P81703, Q9R029	Gene names	Birc1e, Naip-rs3, Naip5
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1e (Neuronal apoptosis inhibitory protein 5).

BIR1G_MOUSE
NC score	0.991761 (rank : 6)	θ value	0 (rank : 5)
Query Neighborhood Hits	61	Target Neighborhood Hits	92	Shared Neighborhood Hits	41
SwissProt Accessions	Q9JIB3	Gene names	Birc1g, Naip7
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1g (Neuronal apoptosis inhibitory protein 7).

CAR12_HUMAN
NC score	0.761701 (rank : 7)	θ value	7.25919e-50 (rank : 7)
Query Neighborhood Hits	61	Target Neighborhood Hits	132	Shared Neighborhood Hits	35
SwissProt Accessions	Q9NPP4, Q96J81, Q96J82, Q96J83	Gene names	CARD12, CLAN, CLAN1
Domain Architecture
Description	Caspase recruitment domain-containing protein 12 (Ice protease- activating factor) (Ipaf) (CARD, LRR, and NACHT-containing protein) (Clan protein).

BIRC4_MOUSE
NC score	0.728339 (rank : 8)	θ value	1.20211e-36 (rank : 11)
Query Neighborhood Hits	61	Target Neighborhood Hits	89	Shared Neighborhood Hits	17
SwissProt Accessions	Q60989, O08865	Gene names	Birc4, Aipa, Api3, Miha, Xiap
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 4 (Inhibitor of apoptosis protein 3) (X-linked inhibitor of apoptosis protein) (X-linked IAP) (IAP homolog A) (MIAP3) (MIAP-3).

BIRC4_HUMAN
NC score	0.721752 (rank : 9)	θ value	3.61944e-33 (rank : 13)
Query Neighborhood Hits	61	Target Neighborhood Hits	89	Shared Neighborhood Hits	17
SwissProt Accessions	P98170, Q9NQ14	Gene names	BIRC4, API3, IAP3, XIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 4 (Inhibitor of apoptosis protein 3) (X-linked inhibitor of apoptosis protein) (X-linked IAP) (IAP-like protein) (HILP).

BIRC2_HUMAN
NC score	0.713640 (rank : 10)	θ value	5.76516e-39 (rank : 8)
Query Neighborhood Hits	61	Target Neighborhood Hits	142	Shared Neighborhood Hits	20
SwissProt Accessions	Q13490, Q16516, Q4TTG0	Gene names	BIRC2, API1, IAP2, MIHB
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (HIAP2) (HIAP-2) (C-IAP1) (TNFR2-TRAF signaling complex protein 2) (IAP homolog B).

BIRC2_MOUSE
NC score	0.709813 (rank : 11)	θ value	9.83387e-39 (rank : 9)
Query Neighborhood Hits	61	Target Neighborhood Hits	137	Shared Neighborhood Hits	21
SwissProt Accessions	Q62210, O08864	Gene names	Birc2, Birc3, Iap2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (MIAP2) (MIAP-2).

BIRC3_HUMAN
NC score	0.706491 (rank : 12)	θ value	1.20211e-36 (rank : 10)
Query Neighborhood Hits	61	Target Neighborhood Hits	133	Shared Neighborhood Hits	18
SwissProt Accessions	Q13489, Q16628, Q9HC27, Q9UP46	Gene names	BIRC3, API2, IAP1, MIHC
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (HIAP1) (HIAP-1) (C-IAP2) (TNFR2-TRAF signaling complex protein 1) (IAP homolog C) (Apoptosis inhibitor 2) (API2).

BIRC3_MOUSE
NC score	0.703636 (rank : 13)	θ value	2.67802e-36 (rank : 12)
Query Neighborhood Hits	61	Target Neighborhood Hits	113	Shared Neighborhood Hits	17
SwissProt Accessions	O08863	Gene names	Birc3, Birc2, Iap1
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (MIAP1) (MIAP-1).

BIRC8_HUMAN
NC score	0.635489 (rank : 14)	θ value	1.99529e-15 (rank : 15)
Query Neighborhood Hits	61	Target Neighborhood Hits	121	Shared Neighborhood Hits	17
SwissProt Accessions	Q96P09, Q96RW5	Gene names	BIRC8, ILP2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 8 (Inhibitor of apoptosis- like protein 2) (IAP-like protein 2) (ILP-2) (Testis-specific inhibitor of apoptosis).

BIRC5_MOUSE
NC score	0.633501 (rank : 15)	θ value	2.52405e-10 (rank : 16)
Query Neighborhood Hits	61	Target Neighborhood Hits	19	Shared Neighborhood Hits	17
SwissProt Accessions	O70201, Q923F7, Q9WU53, Q9WU54	Gene names	Birc5, Api4, Iap4
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 5 (Apoptosis inhibitor survivin) (Apoptosis inhibitor 4) (TIAP).

BIRC5_HUMAN
NC score	0.629823 (rank : 16)	θ value	1.63604e-09 (rank : 17)
Query Neighborhood Hits	61	Target Neighborhood Hits	20	Shared Neighborhood Hits	17
SwissProt Accessions	O15392, Q2I3N8, Q4VGX0, Q53F61, Q5MGC6, Q6FHL2, Q75SP2, Q9P2W8	Gene names	BIRC5, API4, IAP4
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 5 (Apoptosis inhibitor survivin) (Apoptosis inhibitor 4).

BIRC7_HUMAN
NC score	0.629515 (rank : 17)	θ value	2.97466e-19 (rank : 14)
Query Neighborhood Hits	61	Target Neighborhood Hits	185	Shared Neighborhood Hits	17
SwissProt Accessions	Q96CA5, Q9BQV0, Q9H2A8, Q9HAP7	Gene names	BIRC7, KIAP, LIVIN, MLIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 7 (Kidney inhibitor of apoptosis protein) (KIAP) (Melanoma inhibitor of apoptosis protein) (ML-IAP) (Livin).

LRC31_HUMAN
NC score	0.336124 (rank : 18)	θ value	0.000270298 (rank : 31)
Query Neighborhood Hits	61	Target Neighborhood Hits	139	Shared Neighborhood Hits	31
SwissProt Accessions	Q6UY01, Q8N848, Q9H5N5	Gene names	LRRC31
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 31.

BIRC6_HUMAN
NC score	0.331518 (rank : 19)	θ value	7.59969e-07 (rank : 21)
Query Neighborhood Hits	61	Target Neighborhood Hits	161	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NR09, Q9ULD1	Gene names	BIRC6, KIAA1289
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 6 (Ubiquitin-conjugating BIR-domain enzyme apollon).

NAL10_MOUSE
NC score	0.312183 (rank : 20)	θ value	3.77169e-06 (rank : 24)
Query Neighborhood Hits	61	Target Neighborhood Hits	46	Shared Neighborhood Hits	28
SwissProt Accessions	Q8CCN1	Gene names	Nalp10, Pynod
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 10.

CAR15_MOUSE
NC score	0.298380 (rank : 21)	θ value	3.19293e-05 (rank : 25)
Query Neighborhood Hits	61	Target Neighborhood Hits	93	Shared Neighborhood Hits	29
SwissProt Accessions	Q8K3Z0	Gene names	Card15, Nod2
Domain Architecture
Description	Caspase recruitment domain-containing protein 15 (Protein Nod2).

NALP1_HUMAN
NC score	0.297279 (rank : 22)	θ value	3.08544e-08 (rank : 19)
Query Neighborhood Hits	61	Target Neighborhood Hits	138	Shared Neighborhood Hits	29
SwissProt Accessions	Q9C000, Q9BZZ8, Q9BZZ9, Q9HAV8, Q9UFT4, Q9Y2E0	Gene names	NALP1, CARD7, DEFCAP, KIAA0926, NAC
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 1 (Death effector filament- forming ced-4-like apoptosis protein) (Nucleotide-binding domain and caspase recruitment domain) (Caspase recruitment domain protein 7).

NALP2_HUMAN
NC score	0.291805 (rank : 23)	θ value	2.79066e-09 (rank : 18)
Query Neighborhood Hits	61	Target Neighborhood Hits	65	Shared Neighborhood Hits	29
SwissProt Accessions	Q9NX02, Q53FL5, Q59G09, Q8IXT0, Q9BVN5, Q9H6G6, Q9HAV9, Q9NWK3	Gene names	NALP2, NBS1, PAN1, PYPAF2
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 2 (PYRIN domain and NACHT domain-containing protein 1) (PYRIN-containing APAF1-like protein 2) (Nucleotide-binding site protein 1).

NAL10_HUMAN
NC score	0.286000 (rank : 24)	θ value	0.000121331 (rank : 28)
Query Neighborhood Hits	61	Target Neighborhood Hits	55	Shared Neighborhood Hits	28
SwissProt Accessions	Q86W26, Q6JGT0	Gene names	NALP10, NOD8, PYNOD
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 10 (Nucleotide-binding oligomerization domain protein 8).

NALP7_HUMAN
NC score	0.279722 (rank : 25)	θ value	1.29631e-06 (rank : 23)
Query Neighborhood Hits	61	Target Neighborhood Hits	65	Shared Neighborhood Hits	31
SwissProt Accessions	Q8WX94, Q7RTR1	Gene names	NALP7, NOD12, PYPAF3
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 7 (PYRIN-containing APAF1-like protein 3).

NAL13_HUMAN
NC score	0.277725 (rank : 26)	θ value	0.000121331 (rank : 29)
Query Neighborhood Hits	61	Target Neighborhood Hits	93	Shared Neighborhood Hits	33
SwissProt Accessions	Q86W25, Q7RTR5	Gene names	NALP13, NOD14
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 13 (Nucleotide-binding oligomerization domain protein 14).

CAR15_HUMAN
NC score	0.269204 (rank : 27)	θ value	0.00134147 (rank : 33)
Query Neighborhood Hits	61	Target Neighborhood Hits	77	Shared Neighborhood Hits	30
SwissProt Accessions	Q9HC29, Q96RH5, Q96RH6, Q96RH8	Gene names	CARD15, IBD1, NOD2
Domain Architecture
Description	Caspase recruitment domain-containing protein 15 (Protein Nod2) (Inflammatory bowel disease protein 1).

NALP4_HUMAN
NC score	0.268038 (rank : 28)	θ value	1.99992e-07 (rank : 20)
Query Neighborhood Hits	61	Target Neighborhood Hits	81	Shared Neighborhood Hits	29
SwissProt Accessions	Q96MN2, Q86W87, Q96AY6	Gene names	NALP4, PAN2, PYPAF4, RNH2
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 4 (PYRIN-containing APAF1-like protein 4) (PAAD and NACHT-containing protein 2) (PYRIN and NACHT- containing protein 2) (Ribonuclease inhibitor 2).

NALP6_MOUSE
NC score	0.255729 (rank : 29)	θ value	0.00509761 (rank : 34)
Query Neighborhood Hits	61	Target Neighborhood Hits	55	Shared Neighborhood Hits	28
SwissProt Accessions	Q91WS2, Q8K0L4	Gene names	Nalp6, Pypaf5
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 6 (PYRIN-containing APAF1-like protein 5-like).

NAL12_HUMAN
NC score	0.254762 (rank : 30)	θ value	1.29631e-06 (rank : 22)
Query Neighborhood Hits	61	Target Neighborhood Hits	96	Shared Neighborhood Hits	30
SwissProt Accessions	P59046, Q8NEU4, Q9BY26	Gene names	NALP12, PYPAF7, RNO
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 12 (PYRIN-containing APAF1-like protein 7) (Monarch-1) (Regulated by nitric oxide).

NALP6_HUMAN
NC score	0.249306 (rank : 31)	θ value	0.000602161 (rank : 32)
Query Neighborhood Hits	61	Target Neighborhood Hits	52	Shared Neighborhood Hits	28
SwissProt Accessions	P59044	Gene names	NALP6, PYPAF5
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 6 (PYRIN-containing APAF1-like protein 5).

NAL14_HUMAN
NC score	0.242507 (rank : 32)	θ value	0.00020696 (rank : 30)
Query Neighborhood Hits	61	Target Neighborhood Hits	76	Shared Neighborhood Hits	31
SwissProt Accessions	Q86W24, Q7RTR6	Gene names	NALP14, NOD5
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 14 (Nucleotide-binding oligomerization domain protein 5).

CIAS1_HUMAN
NC score	0.236951 (rank : 33)	θ value	9.29e-05 (rank : 27)
Query Neighborhood Hits	61	Target Neighborhood Hits	76	Shared Neighborhood Hits	29
SwissProt Accessions	Q96P20, O75434, Q59H68, Q5JQS8, Q5JQS9, Q6TG35, Q8TCW0, Q8TEU9, Q8WXH9	Gene names	CIAS1, NALP3, PYPAF1
Domain Architecture
Description	Cold autoinflammatory syndrome 1 protein (Cryopyrin) (NACHT-, LRR- and PYD-containing protein 3) (PYRIN-containing APAF1-like protein 1) (Angiotensin/vasopressin receptor AII/AVP-like).

CIAS1_MOUSE
NC score	0.215998 (rank : 34)	θ value	3.19293e-05 (rank : 26)
Query Neighborhood Hits	61	Target Neighborhood Hits	67	Shared Neighborhood Hits	29
SwissProt Accessions	Q8R4B8, Q6JEL0	Gene names	Cias1, Mmig1, Nalp3, Pypaf1
Domain Architecture
Description	Cold autoinflammatory syndrome 1 protein homolog (PYRIN-containing APAF1-like protein 1) (Mast cell maturation-associated-inducible protein 1) (Cryopyrin).

CARD4_MOUSE
NC score	0.184730 (rank : 35)	θ value	0.0961366 (rank : 38)
Query Neighborhood Hits	61	Target Neighborhood Hits	85	Shared Neighborhood Hits	30
SwissProt Accessions	Q8BHB0, Q8BUT6	Gene names	Card4
Domain Architecture
Description	Caspase recruitment domain-containing protein 4.

C2TA_MOUSE
NC score	0.183230 (rank : 36)	θ value	0.0252991 (rank : 35)
Query Neighborhood Hits	61	Target Neighborhood Hits	131	Shared Neighborhood Hits	30
SwissProt Accessions	P79621, O46787, O78036, O78109, Q31115, Q9TPP1	Gene names	Ciita, C2ta, Mhc2ta
Domain Architecture
Description	MHC class II transactivator (CIITA).

NALP5_HUMAN
NC score	0.176138 (rank : 37)	θ value	0.279714 (rank : 39)
Query Neighborhood Hits	61	Target Neighborhood Hits	88	Shared Neighborhood Hits	30
SwissProt Accessions	P59047, Q86W29	Gene names	NALP5, MATER
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Mater protein homolog).

NALP5_MOUSE
NC score	0.169297 (rank : 38)	θ value	5.27518 (rank : 54)
Query Neighborhood Hits	61	Target Neighborhood Hits	560	Shared Neighborhood Hits	32
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

CARD4_HUMAN
NC score	0.160692 (rank : 39)	θ value	0.62314 (rank : 40)
Query Neighborhood Hits	61	Target Neighborhood Hits	102	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y239, Q8IWF5	Gene names	CARD4, NOD1
Domain Architecture
Description	Caspase recruitment domain-containing protein 4 (Protein Nod1).

NAL11_HUMAN
NC score	0.157155 (rank : 40)	θ value	θ > 10 (rank : 73)
Query Neighborhood Hits	61	Target Neighborhood Hits	66	Shared Neighborhood Hits	23
SwissProt Accessions	P59045, Q53ZZ0, Q8NBF5	Gene names	NALP11, NOD17, PYPAF6
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 11 (PYRIN-containing APAF1-like protein 6) (Nucleotide-binding oligomerization domain protein 17).

RINI_HUMAN
NC score	0.140639 (rank : 41)	θ value	θ > 10 (rank : 80)
Query Neighborhood Hits	61	Target Neighborhood Hits	78	Shared Neighborhood Hits	21
SwissProt Accessions	P13489	Gene names	RNH1, PRI, RNH
Domain Architecture
Description	Ribonuclease inhibitor (Ribonuclease/angiogenin inhibitor 1) (RAI) (Placental ribonuclease inhibitor) (RNase inhibitor) (RI).

RINI_MOUSE
NC score	0.137478 (rank : 42)	θ value	θ > 10 (rank : 81)
Query Neighborhood Hits	61	Target Neighborhood Hits	87	Shared Neighborhood Hits	22
SwissProt Accessions	Q91VI7, Q924P4	Gene names	Rnh1, Rnh
Domain Architecture	No domain graphic available
Description	Ribonuclease inhibitor (Ribonuclease/angiogenin inhibitor 1).

RNF26_HUMAN
NC score	0.128284 (rank : 43)	θ value	θ > 10 (rank : 83)
Query Neighborhood Hits	61	Target Neighborhood Hits	95	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BY78	Gene names	RNF26
Domain Architecture	No domain graphic available
Description	RING finger protein 26.

C2TA_HUMAN
NC score	0.125016 (rank : 44)	θ value	3.0926 (rank : 49)
Query Neighborhood Hits	61	Target Neighborhood Hits	190	Shared Neighborhood Hits	26
SwissProt Accessions	P33076	Gene names	CIITA, MHC2TA
Domain Architecture
Description	MHC class II transactivator (CIITA).

RFFL_MOUSE
NC score	0.115594 (rank : 45)	θ value	θ > 10 (rank : 77)
Query Neighborhood Hits	61	Target Neighborhood Hits	145	Shared Neighborhood Hits	9
SwissProt Accessions	Q6ZQM0, Q5SVC2, Q5SVC4, Q9D543, Q9D9B1	Gene names	Rffl
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (Fring).

RNF34_MOUSE
NC score	0.114039 (rank : 46)	θ value	θ > 10 (rank : 85)
Query Neighborhood Hits	61	Target Neighborhood Hits	160	Shared Neighborhood Hits	9
SwissProt Accessions	Q99KR6, Q3UV45	Gene names	Rnf34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (Phafin-1).

RFFL_HUMAN
NC score	0.113645 (rank : 47)	θ value	θ > 10 (rank : 76)
Query Neighborhood Hits	61	Target Neighborhood Hits	175	Shared Neighborhood Hits	9
SwissProt Accessions	Q8WZ73, Q8NHW0, Q8TBY7, Q96BE6	Gene names	RFFL, RNF189, RNF34L
Domain Architecture	No domain graphic available
Description	Rififylin (RING finger and FYVE-like domain-containing protein 1) (FYVE-RING finger protein Sakura) (Fring) (Caspases-8 and -10- associated RING finger protein 2) (CARP-2) (Caspase regulator CARP2) (RING finger protein 189) (RING finger protein 34-like).

RNF34_HUMAN
NC score	0.113492 (rank : 48)	θ value	θ > 10 (rank : 84)
Query Neighborhood Hits	61	Target Neighborhood Hits	153	Shared Neighborhood Hits	9
SwissProt Accessions	Q969K3, Q8NG47, Q9H6W8	Gene names	RNF34
Domain Architecture	No domain graphic available
Description	RING finger protein 34 (RING finger protein RIFF) (FYVE-RING finger protein Momo) (Human RING finger homologous to inhibitor of apoptosis protein) (hRFI) (Caspases-8 and -10-associated RING finger protein 1) (CARP-1) (Caspase regulator CARP1).

RKHD1_HUMAN
NC score	0.086911 (rank : 49)	θ value	θ > 10 (rank : 82)
Query Neighborhood Hits	61	Target Neighborhood Hits	163	Shared Neighborhood Hits	8
SwissProt Accessions	Q86XN8	Gene names	RKHD1, KIAA2031
Domain Architecture
Description	RING finger and KH domain-containing protein 1.

LRC34_HUMAN
NC score	0.083825 (rank : 50)	θ value	θ > 10 (rank : 67)
Query Neighborhood Hits	61	Target Neighborhood Hits	67	Shared Neighborhood Hits	21
SwissProt Accessions	Q8IZ02	Gene names	LRRC34
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 34.

MYLIP_HUMAN
NC score	0.083342 (rank : 51)	θ value	θ > 10 (rank : 71)
Query Neighborhood Hits	61	Target Neighborhood Hits	162	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WY64, Q9BU73, Q9NRL9, Q9UHE7	Gene names	MYLIP, BZF1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

CGRF1_HUMAN
NC score	0.078956 (rank : 52)	θ value	θ > 10 (rank : 65)
Query Neighborhood Hits	61	Target Neighborhood Hits	51	Shared Neighborhood Hits	8
SwissProt Accessions	Q99675, Q96BX2	Gene names	CGRRF1, CGR19
Domain Architecture	No domain graphic available
Description	Cell growth regulator with RING finger domain 1 (Cell growth regulatory gene 19 protein).

CGRF1_MOUSE
NC score	0.076999 (rank : 53)	θ value	θ > 10 (rank : 66)
Query Neighborhood Hits	61	Target Neighborhood Hits	47	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BMJ7, Q3U3F1, Q8CI24	Gene names	Cgrrf1, Cgr19
Domain Architecture	No domain graphic available
Description	Cell growth regulator with RING finger domain 1 (Cell growth regulatory gene 19 protein).

LRC34_MOUSE
NC score	0.076063 (rank : 54)	θ value	θ > 10 (rank : 68)
Query Neighborhood Hits	61	Target Neighborhood Hits	58	Shared Neighborhood Hits	19
SwissProt Accessions	Q9DAM1	Gene names	Lrrc34
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 34.

MYLIP_MOUSE
NC score	0.069055 (rank : 55)	θ value	θ > 10 (rank : 72)
Query Neighborhood Hits	61	Target Neighborhood Hits	139	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BM54, Q3TX01, Q8BLY9, Q91Z47	Gene names	Mylip
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

CF154_HUMAN
NC score	0.068149 (rank : 56)	θ value	θ > 10 (rank : 64)
Query Neighborhood Hits	61	Target Neighborhood Hits	36	Shared Neighborhood Hits	18
SwissProt Accessions	Q5JTD7	Gene names	C6orf154
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf154.

NEURL_MOUSE
NC score	0.066032 (rank : 57)	θ value	θ > 10 (rank : 75)
Query Neighborhood Hits	61	Target Neighborhood Hits	106	Shared Neighborhood Hits	8
SwissProt Accessions	Q923S6, Q91ZT6, Q9CWF1, Q9QWF1	Gene names	Neurl, Neurl1
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (m-neuralized 1) (m-neu1).

NEUL1_HUMAN
NC score	0.063827 (rank : 58)	θ value	θ > 10 (rank : 74)
Query Neighborhood Hits	61	Target Neighborhood Hits	114	Shared Neighborhood Hits	8
SwissProt Accessions	O76050, Q5TDR2, Q5TDR3, Q8TAN0, Q9H463	Gene names	NEURL, NEURL1, RNF67
Domain Architecture	No domain graphic available
Description	Neuralized-like protein 1 (h-neuralized 1) (h-neu) (RING finger protein 67).

CARD8_HUMAN
NC score	0.062626 (rank : 59)	θ value	θ > 10 (rank : 63)
Query Neighborhood Hits	61	Target Neighborhood Hits	22	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y2G2, Q6PGP8, Q96P82	Gene names	CARD8, KIAA0955, NDPP1
Domain Architecture
Description	Caspase recruitment domain-containing protein 8 (Apoptotic protein NDPP1) (DACAR) (CARD-inhibitor of NF-kappa-B-activating ligand) (CARDINAL) (Tumor-up-regulated CARD-containing antagonist of CASP9) (TUCAN).

ASC_MOUSE
NC score	0.059139 (rank : 60)	θ value	θ > 10 (rank : 62)
Query Neighborhood Hits	61	Target Neighborhood Hits	17	Shared Neighborhood Hits	11
SwissProt Accessions	Q9EPB4, Q9D2W9	Gene names	Pycard, Asc
Domain Architecture
Description	Apoptosis-associated speck-like protein containing a CARD (mASC) (PYD and CARD domain-containing protein).

LRSM1_MOUSE
NC score	0.058263 (rank : 61)	θ value	θ > 10 (rank : 69)
Query Neighborhood Hits	61	Target Neighborhood Hits	874	Shared Neighborhood Hits	18
SwissProt Accessions	Q80ZI6	Gene names	Lrsam1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase).

RGP1_HUMAN
NC score	0.051860 (rank : 62)	θ value	θ > 10 (rank : 78)
Query Neighborhood Hits	61	Target Neighborhood Hits	124	Shared Neighborhood Hits	17
SwissProt Accessions	P46060	Gene names	RANGAP1
Domain Architecture
Description	Ran GTPase-activating protein 1.

MGRN1_MOUSE
NC score	0.051300 (rank : 63)	θ value	θ > 10 (rank : 70)
Query Neighborhood Hits	61	Target Neighborhood Hits	149	Shared Neighborhood Hits	8
SwissProt Accessions	Q9D074, Q3U5V9, Q3UDA1, Q6ZQ97, Q8BZM9	Gene names	Mgrn1, Kiaa0544
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1).

RGP1_MOUSE
NC score	0.050980 (rank : 64)	θ value	θ > 10 (rank : 79)
Query Neighborhood Hits	61	Target Neighborhood Hits	105	Shared Neighborhood Hits	17
SwissProt Accessions	P46061, Q60801	Gene names	Rangap1, Fug1
Domain Architecture
Description	Ran GTPase-activating protein 1.

LRC18_MOUSE
NC score	0.047858 (rank : 65)	θ value	0.0330416 (rank : 36)
Query Neighborhood Hits	61	Target Neighborhood Hits	224	Shared Neighborhood Hits	14
SwissProt Accessions	Q9CQ07, Q6P8T8, Q80ZT3, Q9CW01, Q9DA89	Gene names	Lrrc18, Mtlr1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 18 (Testis-specific LRR protein).

LRC18_HUMAN
NC score	0.039788 (rank : 66)	θ value	2.36792 (rank : 46)
Query Neighborhood Hits	61	Target Neighborhood Hits	217	Shared Neighborhood Hits	13
SwissProt Accessions	Q8N456, Q6UY02	Gene names	LRRC18
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 18.

TLR9_MOUSE
NC score	0.035687 (rank : 67)	θ value	1.81305 (rank : 45)
Query Neighborhood Hits	61	Target Neighborhood Hits	291	Shared Neighborhood Hits	18
SwissProt Accessions	Q9EQU3, Q99MF2, Q99MQ8	Gene names	Tlr9
Domain Architecture
Description	Toll-like receptor 9 precursor (CD289 antigen).

LRC39_HUMAN
NC score	0.029163 (rank : 68)	θ value	1.81305 (rank : 44)
Query Neighborhood Hits	61	Target Neighborhood Hits	274	Shared Neighborhood Hits	17
SwissProt Accessions	Q96DD0, Q5VVK7	Gene names	LRRC39
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 39 (Densin hlg).

LRC8B_MOUSE
NC score	0.022824 (rank : 69)	θ value	0.0330416 (rank : 37)
Query Neighborhood Hits	61	Target Neighborhood Hits	283	Shared Neighborhood Hits	15
SwissProt Accessions	Q5DU41	Gene names	Lrrc8b, Kiaa0231
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 8B.

ANLN_HUMAN
NC score	0.018069 (rank : 70)	θ value	0.813845 (rank : 42)
Query Neighborhood Hits	61	Target Neighborhood Hits	222	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NQW6, Q5CZ78, Q6NSK5, Q9H8Y4, Q9NVN9, Q9NVP0	Gene names	ANLN
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

TLR13_MOUSE
NC score	0.010090 (rank : 71)	θ value	2.36792 (rank : 48)
Query Neighborhood Hits	61	Target Neighborhood Hits	335	Shared Neighborhood Hits	17
SwissProt Accessions	Q6R5N8, Q3TDS2	Gene names	Tlr13
Domain Architecture	No domain graphic available
Description	Toll-like receptor 13 precursor.

ZFY27_HUMAN
NC score	0.007970 (rank : 72)	θ value	6.88961 (rank : 58)
Query Neighborhood Hits	61	Target Neighborhood Hits	64	Shared Neighborhood Hits	2
SwissProt Accessions	Q5T4F4, Q5T4F1, Q5T4F2, Q5T4F3, Q8N1K0, Q8N6D6, Q8NCA0, Q8NDE4, Q96M08	Gene names	ZFYVE27
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 27.

LRRN1_MOUSE
NC score	0.007881 (rank : 73)	θ value	2.36792 (rank : 47)
Query Neighborhood Hits	61	Target Neighborhood Hits	508	Shared Neighborhood Hits	10
SwissProt Accessions	Q61809, Q3USY1, Q69ZI0	Gene names	Lrrn1, Kiaa1497
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 1 precursor (Neuronal leucine- rich repeat protein 1) (NLRR-1).

SKP2_MOUSE
NC score	0.007388 (rank : 74)	θ value	6.88961 (rank : 57)
Query Neighborhood Hits	61	Target Neighborhood Hits	69	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z0Z3, Q8BSG7, Q8C8Y9, Q8CB22, Q99J53	Gene names	Skp2
Domain Architecture
Description	S-phase kinase-associated protein 2 (F-box protein Skp2) (Cyclin A/CDK2-associated protein p45) (F-box/WD-40 protein 1) (FWD1).

LRRN1_HUMAN
NC score	0.006989 (rank : 75)	θ value	5.27518 (rank : 53)
Query Neighborhood Hits	61	Target Neighborhood Hits	518	Shared Neighborhood Hits	10
SwissProt Accessions	Q6UXK5, Q3LID5, Q8IYV5, Q9H8V1, Q9P231	Gene names	LRRN1, KIAA1497
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 1 precursor (Neuronal leucine- rich repeat protein 1) (NLRR-1).

CEP63_HUMAN
NC score	0.005874 (rank : 76)	θ value	0.62314 (rank : 41)
Query Neighborhood Hits	61	Target Neighborhood Hits	1005	Shared Neighborhood Hits	5
SwissProt Accessions	Q96MT8, Q96CR0, Q9H8F5, Q9H8N0	Gene names	CEP63
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 63 kDa (Cep63 protein).

TRIB1_MOUSE
NC score	0.004479 (rank : 77)	θ value	1.38821 (rank : 43)
Query Neighborhood Hits	61	Target Neighborhood Hits	593	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K4K4, Q8BFS7, Q8BJR9, Q8BZX3, Q91W04	Gene names	Trib1, Trb1
Domain Architecture	No domain graphic available
Description	Tribbles homolog 1 (TRB-1).

PEX6_MOUSE
NC score	0.004169 (rank : 78)	θ value	8.99809 (rank : 60)
Query Neighborhood Hits	61	Target Neighborhood Hits	94	Shared Neighborhood Hits	5
SwissProt Accessions	Q99LC9, Q6YNQ9	Gene names	Pex6
Domain Architecture	No domain graphic available
Description	Peroxisome assembly factor 2 (PAF-2) (Peroxisomal-type ATPase 1) (Peroxin-6) (Peroxisomal biogenesis factor 6).

PEX6_HUMAN
NC score	0.004158 (rank : 79)	θ value	8.99809 (rank : 59)
Query Neighborhood Hits	61	Target Neighborhood Hits	99	Shared Neighborhood Hits	5
SwissProt Accessions	Q13608, Q8WYQ2, Q99476	Gene names	PEX6, PXAAA1
Domain Architecture
Description	Peroxisome assembly factor 2 (PAF-2) (Peroxisomal-type ATPase 1) (Peroxin-6) (Peroxisomal biogenesis factor 6).

ARHG6_MOUSE
NC score	0.003767 (rank : 80)	θ value	4.03905 (rank : 51)
Query Neighborhood Hits	61	Target Neighborhood Hits	394	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K4I3, Q8C9V4	Gene names	Arhgef6
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6).

TRIB1_HUMAN
NC score	0.003412 (rank : 81)	θ value	4.03905 (rank : 52)
Query Neighborhood Hits	61	Target Neighborhood Hits	598	Shared Neighborhood Hits	5
SwissProt Accessions	Q96RU8, O15180, Q9H2Y8	Gene names	TRIB1, C8FW, GIG2, TRB1
Domain Architecture	No domain graphic available
Description	Tribbles homolog 1 (TRB-1) (SKIP1) (G-protein-coupled receptor-induced protein 2) (GIG-2).

TRIB2_HUMAN
NC score	0.003111 (rank : 82)	θ value	3.0926 (rank : 50)
Query Neighborhood Hits	61	Target Neighborhood Hits	657	Shared Neighborhood Hits	5
SwissProt Accessions	Q92519	Gene names	TRIB2, TRB2
Domain Architecture	No domain graphic available
Description	Tribbles homolog 2 (TRB-2).

TRIB2_MOUSE
NC score	0.002665 (rank : 83)	θ value	5.27518 (rank : 55)
Query Neighborhood Hits	61	Target Neighborhood Hits	653	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K4K3, Q8K017, Q8R2V8	Gene names	Trib2
Domain Architecture	No domain graphic available
Description	Tribbles homolog 2 (TRB-2).

RASL2_HUMAN
NC score	0.001790 (rank : 84)	θ value	8.99809 (rank : 61)
Query Neighborhood Hits	61	Target Neighborhood Hits	161	Shared Neighborhood Hits	2
SwissProt Accessions	O43374, O60286, Q86UW3, Q96QU0	Gene names	RASA4, CAPRI, GAPL, KIAA0538
Domain Architecture
Description	Ras GTPase-activating protein 4 (RasGAP-activating-like protein 2) (Calcium-promoted Ras inactivator).

REST_MOUSE
NC score	-0.001639 (rank : 85)	θ value	6.88961 (rank : 56)
Query Neighborhood Hits	61	Target Neighborhood Hits	1506	Shared Neighborhood Hits	5
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.