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Network neighborhood for query Sequence : NALP6_HUMAN

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NALP6_HUMAN
SwissProt Accessions	P59044	Gene names	NALP6, PYPAF5
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 6 (PYRIN-containing APAF1-like protein 5).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

NALP6_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	52	Target Neighborhood Hits	52	Shared Neighborhood Hits	52
SwissProt Accessions	P59044	Gene names	NALP6, PYPAF5
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 6 (PYRIN-containing APAF1-like protein 5).

NALP6_MOUSE
θ value	0 (rank : 2)	NC score	0.993117 (rank : 2)
Query Neighborhood Hits	52	Target Neighborhood Hits	55	Shared Neighborhood Hits	37
SwissProt Accessions	Q91WS2, Q8K0L4	Gene names	Nalp6, Pypaf5
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 6 (PYRIN-containing APAF1-like protein 5-like).

NAL12_HUMAN
θ value	3.0981e-109 (rank : 3)	NC score	0.946103 (rank : 5)
Query Neighborhood Hits	52	Target Neighborhood Hits	96	Shared Neighborhood Hits	39
SwissProt Accessions	P59046, Q8NEU4, Q9BY26	Gene names	NALP12, PYPAF7, RNO
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 12 (PYRIN-containing APAF1-like protein 7) (Monarch-1) (Regulated by nitric oxide).

CIAS1_MOUSE
θ value	9.65309e-103 (rank : 4)	NC score	0.949456 (rank : 4)
Query Neighborhood Hits	52	Target Neighborhood Hits	67	Shared Neighborhood Hits	37
SwissProt Accessions	Q8R4B8, Q6JEL0	Gene names	Cias1, Mmig1, Nalp3, Pypaf1
Domain Architecture
Description	Cold autoinflammatory syndrome 1 protein homolog (PYRIN-containing APAF1-like protein 1) (Mast cell maturation-associated-inducible protein 1) (Cryopyrin).

CIAS1_HUMAN
θ value	3.66817e-102 (rank : 5)	NC score	0.950265 (rank : 3)
Query Neighborhood Hits	52	Target Neighborhood Hits	76	Shared Neighborhood Hits	37
SwissProt Accessions	Q96P20, O75434, Q59H68, Q5JQS8, Q5JQS9, Q6TG35, Q8TCW0, Q8TEU9, Q8WXH9	Gene names	CIAS1, NALP3, PYPAF1
Domain Architecture
Description	Cold autoinflammatory syndrome 1 protein (Cryopyrin) (NACHT-, LRR- and PYD-containing protein 3) (PYRIN-containing APAF1-like protein 1) (Angiotensin/vasopressin receptor AII/AVP-like).

NAL14_HUMAN
θ value	3.22841e-82 (rank : 6)	NC score	0.932449 (rank : 9)
Query Neighborhood Hits	52	Target Neighborhood Hits	76	Shared Neighborhood Hits	36
SwissProt Accessions	Q86W24, Q7RTR6	Gene names	NALP14, NOD5
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 14 (Nucleotide-binding oligomerization domain protein 5).

NALP4_HUMAN
θ value	1.31376e-75 (rank : 7)	NC score	0.935168 (rank : 6)
Query Neighborhood Hits	52	Target Neighborhood Hits	81	Shared Neighborhood Hits	38
SwissProt Accessions	Q96MN2, Q86W87, Q96AY6	Gene names	NALP4, PAN2, PYPAF4, RNH2
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 4 (PYRIN-containing APAF1-like protein 4) (PAAD and NACHT-containing protein 2) (PYRIN and NACHT- containing protein 2) (Ribonuclease inhibitor 2).

NALP1_HUMAN
θ value	7.97034e-73 (rank : 8)	NC score	0.906399 (rank : 14)
Query Neighborhood Hits	52	Target Neighborhood Hits	138	Shared Neighborhood Hits	36
SwissProt Accessions	Q9C000, Q9BZZ8, Q9BZZ9, Q9HAV8, Q9UFT4, Q9Y2E0	Gene names	NALP1, CARD7, DEFCAP, KIAA0926, NAC
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 1 (Death effector filament- forming ced-4-like apoptosis protein) (Nucleotide-binding domain and caspase recruitment domain) (Caspase recruitment domain protein 7).

NALP2_HUMAN
θ value	1.40689e-69 (rank : 9)	NC score	0.930473 (rank : 10)
Query Neighborhood Hits	52	Target Neighborhood Hits	65	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NX02, Q53FL5, Q59G09, Q8IXT0, Q9BVN5, Q9H6G6, Q9HAV9, Q9NWK3	Gene names	NALP2, NBS1, PAN1, PYPAF2
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 2 (PYRIN domain and NACHT domain-containing protein 1) (PYRIN-containing APAF1-like protein 2) (Nucleotide-binding site protein 1).

NAL10_HUMAN
θ value	1.66577e-62 (rank : 10)	NC score	0.934738 (rank : 7)
Query Neighborhood Hits	52	Target Neighborhood Hits	55	Shared Neighborhood Hits	33
SwissProt Accessions	Q86W26, Q6JGT0	Gene names	NALP10, NOD8, PYNOD
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 10 (Nucleotide-binding oligomerization domain protein 8).

NALP7_HUMAN
θ value	1.19377e-60 (rank : 11)	NC score	0.933698 (rank : 8)
Query Neighborhood Hits	52	Target Neighborhood Hits	65	Shared Neighborhood Hits	37
SwissProt Accessions	Q8WX94, Q7RTR1	Gene names	NALP7, NOD12, PYPAF3
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 7 (PYRIN-containing APAF1-like protein 3).

NALP5_HUMAN
θ value	2.65945e-60 (rank : 12)	NC score	0.909460 (rank : 13)
Query Neighborhood Hits	52	Target Neighborhood Hits	88	Shared Neighborhood Hits	36
SwissProt Accessions	P59047, Q86W29	Gene names	NALP5, MATER
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Mater protein homolog).

NAL10_MOUSE
θ value	3.25095e-58 (rank : 13)	NC score	0.930130 (rank : 11)
Query Neighborhood Hits	52	Target Neighborhood Hits	46	Shared Neighborhood Hits	33
SwissProt Accessions	Q8CCN1	Gene names	Nalp10, Pynod
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 10.

NAL13_HUMAN
θ value	1.84601e-53 (rank : 14)	NC score	0.916441 (rank : 12)
Query Neighborhood Hits	52	Target Neighborhood Hits	93	Shared Neighborhood Hits	34
SwissProt Accessions	Q86W25, Q7RTR5	Gene names	NALP13, NOD14
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 13 (Nucleotide-binding oligomerization domain protein 14).

NALP5_MOUSE
θ value	2.66562e-52 (rank : 15)	NC score	0.842862 (rank : 16)
Query Neighborhood Hits	52	Target Neighborhood Hits	560	Shared Neighborhood Hits	33
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

NAL11_HUMAN
θ value	9.50281e-42 (rank : 16)	NC score	0.900208 (rank : 15)
Query Neighborhood Hits	52	Target Neighborhood Hits	66	Shared Neighborhood Hits	28
SwissProt Accessions	P59045, Q53ZZ0, Q8NBF5	Gene names	NALP11, NOD17, PYPAF6
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 11 (PYRIN-containing APAF1-like protein 6) (Nucleotide-binding oligomerization domain protein 17).

C2TA_MOUSE
θ value	1.5773e-20 (rank : 17)	NC score	0.664487 (rank : 21)
Query Neighborhood Hits	52	Target Neighborhood Hits	131	Shared Neighborhood Hits	32
SwissProt Accessions	P79621, O46787, O78036, O78109, Q31115, Q9TPP1	Gene names	Ciita, C2ta, Mhc2ta
Domain Architecture
Description	MHC class II transactivator (CIITA).

CAR15_MOUSE
θ value	6.20254e-17 (rank : 18)	NC score	0.707392 (rank : 19)
Query Neighborhood Hits	52	Target Neighborhood Hits	93	Shared Neighborhood Hits	33
SwissProt Accessions	Q8K3Z0	Gene names	Card15, Nod2
Domain Architecture
Description	Caspase recruitment domain-containing protein 15 (Protein Nod2).

CAR15_HUMAN
θ value	1.058e-16 (rank : 19)	NC score	0.692781 (rank : 20)
Query Neighborhood Hits	52	Target Neighborhood Hits	77	Shared Neighborhood Hits	33
SwissProt Accessions	Q9HC29, Q96RH5, Q96RH6, Q96RH8	Gene names	CARD15, IBD1, NOD2
Domain Architecture
Description	Caspase recruitment domain-containing protein 15 (Protein Nod2) (Inflammatory bowel disease protein 1).

RINI_HUMAN
θ value	1.16975e-15 (rank : 20)	NC score	0.774969 (rank : 17)
Query Neighborhood Hits	52	Target Neighborhood Hits	78	Shared Neighborhood Hits	26
SwissProt Accessions	P13489	Gene names	RNH1, PRI, RNH
Domain Architecture
Description	Ribonuclease inhibitor (Ribonuclease/angiogenin inhibitor 1) (RAI) (Placental ribonuclease inhibitor) (RNase inhibitor) (RI).

C2TA_HUMAN
θ value	2.20605e-14 (rank : 21)	NC score	0.635106 (rank : 24)
Query Neighborhood Hits	52	Target Neighborhood Hits	190	Shared Neighborhood Hits	28
SwissProt Accessions	P33076	Gene names	CIITA, MHC2TA
Domain Architecture
Description	MHC class II transactivator (CIITA).

RINI_MOUSE
θ value	5.43371e-13 (rank : 22)	NC score	0.764513 (rank : 18)
Query Neighborhood Hits	52	Target Neighborhood Hits	87	Shared Neighborhood Hits	26
SwissProt Accessions	Q91VI7, Q924P4	Gene names	Rnh1, Rnh
Domain Architecture	No domain graphic available
Description	Ribonuclease inhibitor (Ribonuclease/angiogenin inhibitor 1).

CARD4_MOUSE
θ value	1.02475e-11 (rank : 23)	NC score	0.654990 (rank : 22)
Query Neighborhood Hits	52	Target Neighborhood Hits	85	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BHB0, Q8BUT6	Gene names	Card4
Domain Architecture
Description	Caspase recruitment domain-containing protein 4.

CARD4_HUMAN
θ value	3.64472e-09 (rank : 24)	NC score	0.645993 (rank : 23)
Query Neighborhood Hits	52	Target Neighborhood Hits	102	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Y239, Q8IWF5	Gene names	CARD4, NOD1
Domain Architecture
Description	Caspase recruitment domain-containing protein 4 (Protein Nod1).

ASC_MOUSE
θ value	6.43352e-06 (rank : 25)	NC score	0.372990 (rank : 29)
Query Neighborhood Hits	52	Target Neighborhood Hits	17	Shared Neighborhood Hits	15
SwissProt Accessions	Q9EPB4, Q9D2W9	Gene names	Pycard, Asc
Domain Architecture
Description	Apoptosis-associated speck-like protein containing a CARD (mASC) (PYD and CARD domain-containing protein).

BIR1F_MOUSE
θ value	0.00035302 (rank : 26)	NC score	0.227083 (rank : 36)
Query Neighborhood Hits	52	Target Neighborhood Hits	88	Shared Neighborhood Hits	27
SwissProt Accessions	Q9JIB6, O09121, O09122, P81704	Gene names	Birc1f, Naip-rs4, Naip6
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1f (Neuronal apoptosis inhibitory protein 6).

BIR1E_MOUSE
θ value	0.000602161 (rank : 27)	NC score	0.225420 (rank : 37)
Query Neighborhood Hits	52	Target Neighborhood Hits	93	Shared Neighborhood Hits	26
SwissProt Accessions	Q9R016, O09121, O09122, P81703, Q9R029	Gene names	Birc1e, Naip-rs3, Naip5
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1e (Neuronal apoptosis inhibitory protein 5).

BIRC1_HUMAN
θ value	0.000602161 (rank : 28)	NC score	0.249306 (rank : 33)
Query Neighborhood Hits	52	Target Neighborhood Hits	61	Shared Neighborhood Hits	28
SwissProt Accessions	Q13075, O75857, Q13730, Q99796	Gene names	BIRC1, NAIP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1 (Neuronal apoptosis inhibitory protein).

MEFV_HUMAN
θ value	0.000602161 (rank : 29)	NC score	0.100567 (rank : 44)
Query Neighborhood Hits	52	Target Neighborhood Hits	431	Shared Neighborhood Hits	16
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

BIR1G_MOUSE
θ value	0.00175202 (rank : 30)	NC score	0.218397 (rank : 38)
Query Neighborhood Hits	52	Target Neighborhood Hits	92	Shared Neighborhood Hits	26
SwissProt Accessions	Q9JIB3	Gene names	Birc1g, Naip7
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1g (Neuronal apoptosis inhibitory protein 7).

MEFV_MOUSE
θ value	0.00175202 (rank : 31)	NC score	0.189378 (rank : 40)
Query Neighborhood Hits	52	Target Neighborhood Hits	236	Shared Neighborhood Hits	15
SwissProt Accessions	Q9JJ26	Gene names	Mefv
Domain Architecture
Description	Pyrin (Marenostrin).

FBX37_MOUSE
θ value	0.00228821 (rank : 32)	NC score	0.061654 (rank : 46)
Query Neighborhood Hits	52	Target Neighborhood Hits	37	Shared Neighborhood Hits	3
SwissProt Accessions	Q91W61	Gene names	Fbxl15, Fbxo37
Domain Architecture	No domain graphic available
Description	F-box only protein 37 (F-box/LRR-repeat protein 15).

BIR1A_MOUSE
θ value	0.00390308 (rank : 33)	NC score	0.232340 (rank : 35)
Query Neighborhood Hits	52	Target Neighborhood Hits	94	Shared Neighborhood Hits	26
SwissProt Accessions	Q9QWK5, Q9JIB5, Q9R017	Gene names	Birc1a, Naip, Naip1
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1a (Neuronal apoptosis inhibitory protein 1).

FBX37_HUMAN
θ value	0.00509761 (rank : 34)	NC score	0.060465 (rank : 47)
Query Neighborhood Hits	52	Target Neighborhood Hits	38	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H469, Q49AL7, Q5JWA5	Gene names	FBXL15, FBXO37
Domain Architecture	No domain graphic available
Description	F-box only protein 37 (F-box/LRR-repeat protein 15).

CF154_HUMAN
θ value	0.0563607 (rank : 35)	NC score	0.420495 (rank : 26)
Query Neighborhood Hits	52	Target Neighborhood Hits	36	Shared Neighborhood Hits	22
SwissProt Accessions	Q5JTD7	Gene names	C6orf154
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf154.

ASC_HUMAN
θ value	0.0961366 (rank : 36)	NC score	0.307914 (rank : 30)
Query Neighborhood Hits	52	Target Neighborhood Hits	18	Shared Neighborhood Hits	14
SwissProt Accessions	Q9ULZ3, Q96D12, Q9BSZ5, Q9HBD0, Q9NXJ8	Gene names	PYCARD, ASC, CARD5, TMS1
Domain Architecture
Description	Apoptosis-associated speck-like protein containing a CARD (hASC) (PYD and CARD domain-containing protein) (Target of methylation-induced silencing 1) (Caspase recruitment domain-containing protein 5).

CAR12_HUMAN
θ value	0.21417 (rank : 37)	NC score	0.307113 (rank : 31)
Query Neighborhood Hits	52	Target Neighborhood Hits	132	Shared Neighborhood Hits	31
SwissProt Accessions	Q9NPP4, Q96J81, Q96J82, Q96J83	Gene names	CARD12, CLAN, CLAN1
Domain Architecture
Description	Caspase recruitment domain-containing protein 12 (Ice protease- activating factor) (Ipaf) (CARD, LRR, and NACHT-containing protein) (Clan protein).

BIR1B_MOUSE
θ value	0.279714 (rank : 38)	NC score	0.208718 (rank : 39)
Query Neighborhood Hits	52	Target Neighborhood Hits	93	Shared Neighborhood Hits	27
SwissProt Accessions	Q9QUK4, O09124, Q9R030	Gene names	Birc1b, Naip-rs6, Naip2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1b (Neuronal apoptosis inhibitory protein 2).

LRC34_HUMAN
θ value	0.365318 (rank : 39)	NC score	0.433438 (rank : 25)
Query Neighborhood Hits	52	Target Neighborhood Hits	67	Shared Neighborhood Hits	24
SwissProt Accessions	Q8IZ02	Gene names	LRRC34
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 34.

PLCB3_HUMAN
θ value	0.62314 (rank : 40)	NC score	0.010977 (rank : 50)
Query Neighborhood Hits	52	Target Neighborhood Hits	445	Shared Neighborhood Hits	4
SwissProt Accessions	Q01970	Gene names	PLCB3
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 3 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-3) (PLC-beta-3).

ABCA7_MOUSE
θ value	1.81305 (rank : 41)	NC score	0.005405 (rank : 57)
Query Neighborhood Hits	52	Target Neighborhood Hits	111	Shared Neighborhood Hits	2
SwissProt Accessions	Q91V24, Q9JL36	Gene names	Abca7
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 7.

RT09_MOUSE
θ value	1.81305 (rank : 42)	NC score	0.019423 (rank : 49)
Query Neighborhood Hits	52	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D7N3, Q6IS29, Q80W17	Gene names	Mrps9
Domain Architecture	No domain graphic available
Description	28S ribosomal protein S9, mitochondrial precursor (S9mt) (MRP-S9).

AIM2_HUMAN
θ value	2.36792 (rank : 43)	NC score	0.047471 (rank : 48)
Query Neighborhood Hits	52	Target Neighborhood Hits	34	Shared Neighborhood Hits	7
SwissProt Accessions	O14862	Gene names	AIM2
Domain Architecture
Description	Interferon-inducible protein AIM2 (Absent in melanoma 2).

SNPC4_MOUSE
θ value	4.03905 (rank : 44)	NC score	0.009777 (rank : 51)
Query Neighborhood Hits	52	Target Neighborhood Hits	237	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BP86, Q6PGG7, Q80UG9, Q810L1	Gene names	Snapc4
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit).

IRF5_MOUSE
θ value	5.27518 (rank : 45)	NC score	0.005679 (rank : 55)
Query Neighborhood Hits	52	Target Neighborhood Hits	49	Shared Neighborhood Hits	2
SwissProt Accessions	P56477	Gene names	Irf5
Domain Architecture
Description	Interferon regulatory factor 5 (IRF-5).

ATD3A_HUMAN
θ value	6.88961 (rank : 46)	NC score	0.006547 (rank : 54)
Query Neighborhood Hits	52	Target Neighborhood Hits	248	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NVI7, Q8N275, Q96A50	Gene names	ATAD3A
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 3A.

LRC14_HUMAN
θ value	6.88961 (rank : 47)	NC score	0.075438 (rank : 45)
Query Neighborhood Hits	52	Target Neighborhood Hits	57	Shared Neighborhood Hits	15
SwissProt Accessions	Q15048	Gene names	LRRC14, KIAA0014
Domain Architecture
Description	Leucine-rich repeat-containing protein 14.

ATAD3_MOUSE
θ value	8.99809 (rank : 48)	NC score	0.005516 (rank : 56)
Query Neighborhood Hits	52	Target Neighborhood Hits	326	Shared Neighborhood Hits	4
SwissProt Accessions	Q925I1, Q3UE74, Q69ZM7, Q8C6C6	Gene names	Atad3, Atad3a, Kiaa1273
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 3 (AAA-ATPase TOB3).

CA048_HUMAN
θ value	8.99809 (rank : 49)	NC score	0.008940 (rank : 53)
Query Neighborhood Hits	52	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	Q96IY1, Q5SY75, Q9H2M5, Q9NRN8, Q9Y415	Gene names	C1orf48
Domain Architecture	No domain graphic available
Description	Protein C1orf48.

MYLIP_MOUSE
θ value	8.99809 (rank : 50)	NC score	0.009437 (rank : 52)
Query Neighborhood Hits	52	Target Neighborhood Hits	139	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BM54, Q3TX01, Q8BLY9, Q91Z47	Gene names	Mylip
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

RNF31_HUMAN
θ value	8.99809 (rank : 51)	NC score	0.005163 (rank : 58)
Query Neighborhood Hits	52	Target Neighborhood Hits	110	Shared Neighborhood Hits	2
SwissProt Accessions	Q96EP0, Q86VI2, Q8TEI0, Q96GB4, Q96NF1, Q9H5F1, Q9NWD2	Gene names	RNF31, ZIBRA
Domain Architecture
Description	RING finger protein 31 (Zinc in-between-RING-finger ubiquitin- associated domain protein).

TEX14_MOUSE
θ value	8.99809 (rank : 52)	NC score	-0.002891 (rank : 59)
Query Neighborhood Hits	52	Target Neighborhood Hits	1333	Shared Neighborhood Hits	2
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

CARD8_HUMAN
θ value	θ > 10 (rank : 53)	NC score	0.125155 (rank : 42)
Query Neighborhood Hits	52	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y2G2, Q6PGP8, Q96P82	Gene names	CARD8, KIAA0955, NDPP1
Domain Architecture
Description	Caspase recruitment domain-containing protein 8 (Apoptotic protein NDPP1) (DACAR) (CARD-inhibitor of NF-kappa-B-activating ligand) (CARDINAL) (Tumor-up-regulated CARD-containing antagonist of CASP9) (TUCAN).

LRC31_HUMAN
θ value	θ > 10 (rank : 54)	NC score	0.395449 (rank : 27)
Query Neighborhood Hits	52	Target Neighborhood Hits	139	Shared Neighborhood Hits	29
SwissProt Accessions	Q6UY01, Q8N848, Q9H5N5	Gene names	LRRC31
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 31.

LRC34_MOUSE
θ value	θ > 10 (rank : 55)	NC score	0.390319 (rank : 28)
Query Neighborhood Hits	52	Target Neighborhood Hits	58	Shared Neighborhood Hits	24
SwissProt Accessions	Q9DAM1	Gene names	Lrrc34
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 34.

LRC45_HUMAN
θ value	θ > 10 (rank : 56)	NC score	0.121759 (rank : 43)
Query Neighborhood Hits	52	Target Neighborhood Hits	933	Shared Neighborhood Hits	25
SwissProt Accessions	Q96CN5	Gene names	LRRC45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

LRC45_MOUSE
θ value	θ > 10 (rank : 57)	NC score	0.130289 (rank : 41)
Query Neighborhood Hits	52	Target Neighborhood Hits	959	Shared Neighborhood Hits	27
SwissProt Accessions	Q8CIM1, Q3U5Z2	Gene names	Lrrc45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

RGP1_HUMAN
θ value	θ > 10 (rank : 58)	NC score	0.260180 (rank : 32)
Query Neighborhood Hits	52	Target Neighborhood Hits	124	Shared Neighborhood Hits	19
SwissProt Accessions	P46060	Gene names	RANGAP1
Domain Architecture
Description	Ran GTPase-activating protein 1.

RGP1_MOUSE
θ value	θ > 10 (rank : 59)	NC score	0.249138 (rank : 34)
Query Neighborhood Hits	52	Target Neighborhood Hits	105	Shared Neighborhood Hits	20
SwissProt Accessions	P46061, Q60801	Gene names	Rangap1, Fug1
Domain Architecture
Description	Ran GTPase-activating protein 1.

Hits sorted by NC score

NALP6_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	52	Target Neighborhood Hits	52	Shared Neighborhood Hits	52
SwissProt Accessions	P59044	Gene names	NALP6, PYPAF5
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 6 (PYRIN-containing APAF1-like protein 5).

NALP6_MOUSE
NC score	0.993117 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	52	Target Neighborhood Hits	55	Shared Neighborhood Hits	37
SwissProt Accessions	Q91WS2, Q8K0L4	Gene names	Nalp6, Pypaf5
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 6 (PYRIN-containing APAF1-like protein 5-like).

CIAS1_HUMAN
NC score	0.950265 (rank : 3)	θ value	3.66817e-102 (rank : 5)
Query Neighborhood Hits	52	Target Neighborhood Hits	76	Shared Neighborhood Hits	37
SwissProt Accessions	Q96P20, O75434, Q59H68, Q5JQS8, Q5JQS9, Q6TG35, Q8TCW0, Q8TEU9, Q8WXH9	Gene names	CIAS1, NALP3, PYPAF1
Domain Architecture
Description	Cold autoinflammatory syndrome 1 protein (Cryopyrin) (NACHT-, LRR- and PYD-containing protein 3) (PYRIN-containing APAF1-like protein 1) (Angiotensin/vasopressin receptor AII/AVP-like).

CIAS1_MOUSE
NC score	0.949456 (rank : 4)	θ value	9.65309e-103 (rank : 4)
Query Neighborhood Hits	52	Target Neighborhood Hits	67	Shared Neighborhood Hits	37
SwissProt Accessions	Q8R4B8, Q6JEL0	Gene names	Cias1, Mmig1, Nalp3, Pypaf1
Domain Architecture
Description	Cold autoinflammatory syndrome 1 protein homolog (PYRIN-containing APAF1-like protein 1) (Mast cell maturation-associated-inducible protein 1) (Cryopyrin).

NAL12_HUMAN
NC score	0.946103 (rank : 5)	θ value	3.0981e-109 (rank : 3)
Query Neighborhood Hits	52	Target Neighborhood Hits	96	Shared Neighborhood Hits	39
SwissProt Accessions	P59046, Q8NEU4, Q9BY26	Gene names	NALP12, PYPAF7, RNO
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 12 (PYRIN-containing APAF1-like protein 7) (Monarch-1) (Regulated by nitric oxide).

NALP4_HUMAN
NC score	0.935168 (rank : 6)	θ value	1.31376e-75 (rank : 7)
Query Neighborhood Hits	52	Target Neighborhood Hits	81	Shared Neighborhood Hits	38
SwissProt Accessions	Q96MN2, Q86W87, Q96AY6	Gene names	NALP4, PAN2, PYPAF4, RNH2
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 4 (PYRIN-containing APAF1-like protein 4) (PAAD and NACHT-containing protein 2) (PYRIN and NACHT- containing protein 2) (Ribonuclease inhibitor 2).

NAL10_HUMAN
NC score	0.934738 (rank : 7)	θ value	1.66577e-62 (rank : 10)
Query Neighborhood Hits	52	Target Neighborhood Hits	55	Shared Neighborhood Hits	33
SwissProt Accessions	Q86W26, Q6JGT0	Gene names	NALP10, NOD8, PYNOD
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 10 (Nucleotide-binding oligomerization domain protein 8).

NALP7_HUMAN
NC score	0.933698 (rank : 8)	θ value	1.19377e-60 (rank : 11)
Query Neighborhood Hits	52	Target Neighborhood Hits	65	Shared Neighborhood Hits	37
SwissProt Accessions	Q8WX94, Q7RTR1	Gene names	NALP7, NOD12, PYPAF3
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 7 (PYRIN-containing APAF1-like protein 3).

NAL14_HUMAN
NC score	0.932449 (rank : 9)	θ value	3.22841e-82 (rank : 6)
Query Neighborhood Hits	52	Target Neighborhood Hits	76	Shared Neighborhood Hits	36
SwissProt Accessions	Q86W24, Q7RTR6	Gene names	NALP14, NOD5
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 14 (Nucleotide-binding oligomerization domain protein 5).

NALP2_HUMAN
NC score	0.930473 (rank : 10)	θ value	1.40689e-69 (rank : 9)
Query Neighborhood Hits	52	Target Neighborhood Hits	65	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NX02, Q53FL5, Q59G09, Q8IXT0, Q9BVN5, Q9H6G6, Q9HAV9, Q9NWK3	Gene names	NALP2, NBS1, PAN1, PYPAF2
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 2 (PYRIN domain and NACHT domain-containing protein 1) (PYRIN-containing APAF1-like protein 2) (Nucleotide-binding site protein 1).

NAL10_MOUSE
NC score	0.930130 (rank : 11)	θ value	3.25095e-58 (rank : 13)
Query Neighborhood Hits	52	Target Neighborhood Hits	46	Shared Neighborhood Hits	33
SwissProt Accessions	Q8CCN1	Gene names	Nalp10, Pynod
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 10.

NAL13_HUMAN
NC score	0.916441 (rank : 12)	θ value	1.84601e-53 (rank : 14)
Query Neighborhood Hits	52	Target Neighborhood Hits	93	Shared Neighborhood Hits	34
SwissProt Accessions	Q86W25, Q7RTR5	Gene names	NALP13, NOD14
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 13 (Nucleotide-binding oligomerization domain protein 14).

NALP5_HUMAN
NC score	0.909460 (rank : 13)	θ value	2.65945e-60 (rank : 12)
Query Neighborhood Hits	52	Target Neighborhood Hits	88	Shared Neighborhood Hits	36
SwissProt Accessions	P59047, Q86W29	Gene names	NALP5, MATER
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Mater protein homolog).

NALP1_HUMAN
NC score	0.906399 (rank : 14)	θ value	7.97034e-73 (rank : 8)
Query Neighborhood Hits	52	Target Neighborhood Hits	138	Shared Neighborhood Hits	36
SwissProt Accessions	Q9C000, Q9BZZ8, Q9BZZ9, Q9HAV8, Q9UFT4, Q9Y2E0	Gene names	NALP1, CARD7, DEFCAP, KIAA0926, NAC
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 1 (Death effector filament- forming ced-4-like apoptosis protein) (Nucleotide-binding domain and caspase recruitment domain) (Caspase recruitment domain protein 7).

NAL11_HUMAN
NC score	0.900208 (rank : 15)	θ value	9.50281e-42 (rank : 16)
Query Neighborhood Hits	52	Target Neighborhood Hits	66	Shared Neighborhood Hits	28
SwissProt Accessions	P59045, Q53ZZ0, Q8NBF5	Gene names	NALP11, NOD17, PYPAF6
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 11 (PYRIN-containing APAF1-like protein 6) (Nucleotide-binding oligomerization domain protein 17).

NALP5_MOUSE
NC score	0.842862 (rank : 16)	θ value	2.66562e-52 (rank : 15)
Query Neighborhood Hits	52	Target Neighborhood Hits	560	Shared Neighborhood Hits	33
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

RINI_HUMAN
NC score	0.774969 (rank : 17)	θ value	1.16975e-15 (rank : 20)
Query Neighborhood Hits	52	Target Neighborhood Hits	78	Shared Neighborhood Hits	26
SwissProt Accessions	P13489	Gene names	RNH1, PRI, RNH
Domain Architecture
Description	Ribonuclease inhibitor (Ribonuclease/angiogenin inhibitor 1) (RAI) (Placental ribonuclease inhibitor) (RNase inhibitor) (RI).

RINI_MOUSE
NC score	0.764513 (rank : 18)	θ value	5.43371e-13 (rank : 22)
Query Neighborhood Hits	52	Target Neighborhood Hits	87	Shared Neighborhood Hits	26
SwissProt Accessions	Q91VI7, Q924P4	Gene names	Rnh1, Rnh
Domain Architecture	No domain graphic available
Description	Ribonuclease inhibitor (Ribonuclease/angiogenin inhibitor 1).

CAR15_MOUSE
NC score	0.707392 (rank : 19)	θ value	6.20254e-17 (rank : 18)
Query Neighborhood Hits	52	Target Neighborhood Hits	93	Shared Neighborhood Hits	33
SwissProt Accessions	Q8K3Z0	Gene names	Card15, Nod2
Domain Architecture
Description	Caspase recruitment domain-containing protein 15 (Protein Nod2).

CAR15_HUMAN
NC score	0.692781 (rank : 20)	θ value	1.058e-16 (rank : 19)
Query Neighborhood Hits	52	Target Neighborhood Hits	77	Shared Neighborhood Hits	33
SwissProt Accessions	Q9HC29, Q96RH5, Q96RH6, Q96RH8	Gene names	CARD15, IBD1, NOD2
Domain Architecture
Description	Caspase recruitment domain-containing protein 15 (Protein Nod2) (Inflammatory bowel disease protein 1).

C2TA_MOUSE
NC score	0.664487 (rank : 21)	θ value	1.5773e-20 (rank : 17)
Query Neighborhood Hits	52	Target Neighborhood Hits	131	Shared Neighborhood Hits	32
SwissProt Accessions	P79621, O46787, O78036, O78109, Q31115, Q9TPP1	Gene names	Ciita, C2ta, Mhc2ta
Domain Architecture
Description	MHC class II transactivator (CIITA).

CARD4_MOUSE
NC score	0.654990 (rank : 22)	θ value	1.02475e-11 (rank : 23)
Query Neighborhood Hits	52	Target Neighborhood Hits	85	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BHB0, Q8BUT6	Gene names	Card4
Domain Architecture
Description	Caspase recruitment domain-containing protein 4.

CARD4_HUMAN
NC score	0.645993 (rank : 23)	θ value	3.64472e-09 (rank : 24)
Query Neighborhood Hits	52	Target Neighborhood Hits	102	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Y239, Q8IWF5	Gene names	CARD4, NOD1
Domain Architecture
Description	Caspase recruitment domain-containing protein 4 (Protein Nod1).

C2TA_HUMAN
NC score	0.635106 (rank : 24)	θ value	2.20605e-14 (rank : 21)
Query Neighborhood Hits	52	Target Neighborhood Hits	190	Shared Neighborhood Hits	28
SwissProt Accessions	P33076	Gene names	CIITA, MHC2TA
Domain Architecture
Description	MHC class II transactivator (CIITA).

LRC34_HUMAN
NC score	0.433438 (rank : 25)	θ value	0.365318 (rank : 39)
Query Neighborhood Hits	52	Target Neighborhood Hits	67	Shared Neighborhood Hits	24
SwissProt Accessions	Q8IZ02	Gene names	LRRC34
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 34.

CF154_HUMAN
NC score	0.420495 (rank : 26)	θ value	0.0563607 (rank : 35)
Query Neighborhood Hits	52	Target Neighborhood Hits	36	Shared Neighborhood Hits	22
SwissProt Accessions	Q5JTD7	Gene names	C6orf154
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf154.

LRC31_HUMAN
NC score	0.395449 (rank : 27)	θ value	θ > 10 (rank : 54)
Query Neighborhood Hits	52	Target Neighborhood Hits	139	Shared Neighborhood Hits	29
SwissProt Accessions	Q6UY01, Q8N848, Q9H5N5	Gene names	LRRC31
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 31.

LRC34_MOUSE
NC score	0.390319 (rank : 28)	θ value	θ > 10 (rank : 55)
Query Neighborhood Hits	52	Target Neighborhood Hits	58	Shared Neighborhood Hits	24
SwissProt Accessions	Q9DAM1	Gene names	Lrrc34
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 34.

ASC_MOUSE
NC score	0.372990 (rank : 29)	θ value	6.43352e-06 (rank : 25)
Query Neighborhood Hits	52	Target Neighborhood Hits	17	Shared Neighborhood Hits	15
SwissProt Accessions	Q9EPB4, Q9D2W9	Gene names	Pycard, Asc
Domain Architecture
Description	Apoptosis-associated speck-like protein containing a CARD (mASC) (PYD and CARD domain-containing protein).

ASC_HUMAN
NC score	0.307914 (rank : 30)	θ value	0.0961366 (rank : 36)
Query Neighborhood Hits	52	Target Neighborhood Hits	18	Shared Neighborhood Hits	14
SwissProt Accessions	Q9ULZ3, Q96D12, Q9BSZ5, Q9HBD0, Q9NXJ8	Gene names	PYCARD, ASC, CARD5, TMS1
Domain Architecture
Description	Apoptosis-associated speck-like protein containing a CARD (hASC) (PYD and CARD domain-containing protein) (Target of methylation-induced silencing 1) (Caspase recruitment domain-containing protein 5).

CAR12_HUMAN
NC score	0.307113 (rank : 31)	θ value	0.21417 (rank : 37)
Query Neighborhood Hits	52	Target Neighborhood Hits	132	Shared Neighborhood Hits	31
SwissProt Accessions	Q9NPP4, Q96J81, Q96J82, Q96J83	Gene names	CARD12, CLAN, CLAN1
Domain Architecture
Description	Caspase recruitment domain-containing protein 12 (Ice protease- activating factor) (Ipaf) (CARD, LRR, and NACHT-containing protein) (Clan protein).

RGP1_HUMAN
NC score	0.260180 (rank : 32)	θ value	θ > 10 (rank : 58)
Query Neighborhood Hits	52	Target Neighborhood Hits	124	Shared Neighborhood Hits	19
SwissProt Accessions	P46060	Gene names	RANGAP1
Domain Architecture
Description	Ran GTPase-activating protein 1.

BIRC1_HUMAN
NC score	0.249306 (rank : 33)	θ value	0.000602161 (rank : 28)
Query Neighborhood Hits	52	Target Neighborhood Hits	61	Shared Neighborhood Hits	28
SwissProt Accessions	Q13075, O75857, Q13730, Q99796	Gene names	BIRC1, NAIP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1 (Neuronal apoptosis inhibitory protein).

RGP1_MOUSE
NC score	0.249138 (rank : 34)	θ value	θ > 10 (rank : 59)
Query Neighborhood Hits	52	Target Neighborhood Hits	105	Shared Neighborhood Hits	20
SwissProt Accessions	P46061, Q60801	Gene names	Rangap1, Fug1
Domain Architecture
Description	Ran GTPase-activating protein 1.

BIR1A_MOUSE
NC score	0.232340 (rank : 35)	θ value	0.00390308 (rank : 33)
Query Neighborhood Hits	52	Target Neighborhood Hits	94	Shared Neighborhood Hits	26
SwissProt Accessions	Q9QWK5, Q9JIB5, Q9R017	Gene names	Birc1a, Naip, Naip1
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1a (Neuronal apoptosis inhibitory protein 1).

BIR1F_MOUSE
NC score	0.227083 (rank : 36)	θ value	0.00035302 (rank : 26)
Query Neighborhood Hits	52	Target Neighborhood Hits	88	Shared Neighborhood Hits	27
SwissProt Accessions	Q9JIB6, O09121, O09122, P81704	Gene names	Birc1f, Naip-rs4, Naip6
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1f (Neuronal apoptosis inhibitory protein 6).

BIR1E_MOUSE
NC score	0.225420 (rank : 37)	θ value	0.000602161 (rank : 27)
Query Neighborhood Hits	52	Target Neighborhood Hits	93	Shared Neighborhood Hits	26
SwissProt Accessions	Q9R016, O09121, O09122, P81703, Q9R029	Gene names	Birc1e, Naip-rs3, Naip5
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1e (Neuronal apoptosis inhibitory protein 5).

BIR1G_MOUSE
NC score	0.218397 (rank : 38)	θ value	0.00175202 (rank : 30)
Query Neighborhood Hits	52	Target Neighborhood Hits	92	Shared Neighborhood Hits	26
SwissProt Accessions	Q9JIB3	Gene names	Birc1g, Naip7
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1g (Neuronal apoptosis inhibitory protein 7).

BIR1B_MOUSE
NC score	0.208718 (rank : 39)	θ value	0.279714 (rank : 38)
Query Neighborhood Hits	52	Target Neighborhood Hits	93	Shared Neighborhood Hits	27
SwissProt Accessions	Q9QUK4, O09124, Q9R030	Gene names	Birc1b, Naip-rs6, Naip2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1b (Neuronal apoptosis inhibitory protein 2).

MEFV_MOUSE
NC score	0.189378 (rank : 40)	θ value	0.00175202 (rank : 31)
Query Neighborhood Hits	52	Target Neighborhood Hits	236	Shared Neighborhood Hits	15
SwissProt Accessions	Q9JJ26	Gene names	Mefv
Domain Architecture
Description	Pyrin (Marenostrin).

LRC45_MOUSE
NC score	0.130289 (rank : 41)	θ value	θ > 10 (rank : 57)
Query Neighborhood Hits	52	Target Neighborhood Hits	959	Shared Neighborhood Hits	27
SwissProt Accessions	Q8CIM1, Q3U5Z2	Gene names	Lrrc45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

CARD8_HUMAN
NC score	0.125155 (rank : 42)	θ value	θ > 10 (rank : 53)
Query Neighborhood Hits	52	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y2G2, Q6PGP8, Q96P82	Gene names	CARD8, KIAA0955, NDPP1
Domain Architecture
Description	Caspase recruitment domain-containing protein 8 (Apoptotic protein NDPP1) (DACAR) (CARD-inhibitor of NF-kappa-B-activating ligand) (CARDINAL) (Tumor-up-regulated CARD-containing antagonist of CASP9) (TUCAN).

LRC45_HUMAN
NC score	0.121759 (rank : 43)	θ value	θ > 10 (rank : 56)
Query Neighborhood Hits	52	Target Neighborhood Hits	933	Shared Neighborhood Hits	25
SwissProt Accessions	Q96CN5	Gene names	LRRC45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

MEFV_HUMAN
NC score	0.100567 (rank : 44)	θ value	0.000602161 (rank : 29)
Query Neighborhood Hits	52	Target Neighborhood Hits	431	Shared Neighborhood Hits	16
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

LRC14_HUMAN
NC score	0.075438 (rank : 45)	θ value	6.88961 (rank : 47)
Query Neighborhood Hits	52	Target Neighborhood Hits	57	Shared Neighborhood Hits	15
SwissProt Accessions	Q15048	Gene names	LRRC14, KIAA0014
Domain Architecture
Description	Leucine-rich repeat-containing protein 14.

FBX37_MOUSE
NC score	0.061654 (rank : 46)	θ value	0.00228821 (rank : 32)
Query Neighborhood Hits	52	Target Neighborhood Hits	37	Shared Neighborhood Hits	3
SwissProt Accessions	Q91W61	Gene names	Fbxl15, Fbxo37
Domain Architecture	No domain graphic available
Description	F-box only protein 37 (F-box/LRR-repeat protein 15).

FBX37_HUMAN
NC score	0.060465 (rank : 47)	θ value	0.00509761 (rank : 34)
Query Neighborhood Hits	52	Target Neighborhood Hits	38	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H469, Q49AL7, Q5JWA5	Gene names	FBXL15, FBXO37
Domain Architecture	No domain graphic available
Description	F-box only protein 37 (F-box/LRR-repeat protein 15).

AIM2_HUMAN
NC score	0.047471 (rank : 48)	θ value	2.36792 (rank : 43)
Query Neighborhood Hits	52	Target Neighborhood Hits	34	Shared Neighborhood Hits	7
SwissProt Accessions	O14862	Gene names	AIM2
Domain Architecture
Description	Interferon-inducible protein AIM2 (Absent in melanoma 2).

RT09_MOUSE
NC score	0.019423 (rank : 49)	θ value	1.81305 (rank : 42)
Query Neighborhood Hits	52	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D7N3, Q6IS29, Q80W17	Gene names	Mrps9
Domain Architecture	No domain graphic available
Description	28S ribosomal protein S9, mitochondrial precursor (S9mt) (MRP-S9).

PLCB3_HUMAN
NC score	0.010977 (rank : 50)	θ value	0.62314 (rank : 40)
Query Neighborhood Hits	52	Target Neighborhood Hits	445	Shared Neighborhood Hits	4
SwissProt Accessions	Q01970	Gene names	PLCB3
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 3 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-3) (PLC-beta-3).

SNPC4_MOUSE
NC score	0.009777 (rank : 51)	θ value	4.03905 (rank : 44)
Query Neighborhood Hits	52	Target Neighborhood Hits	237	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BP86, Q6PGG7, Q80UG9, Q810L1	Gene names	Snapc4
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit).

MYLIP_MOUSE
NC score	0.009437 (rank : 52)	θ value	8.99809 (rank : 50)
Query Neighborhood Hits	52	Target Neighborhood Hits	139	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BM54, Q3TX01, Q8BLY9, Q91Z47	Gene names	Mylip
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

CA048_HUMAN
NC score	0.008940 (rank : 53)	θ value	8.99809 (rank : 49)
Query Neighborhood Hits	52	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	Q96IY1, Q5SY75, Q9H2M5, Q9NRN8, Q9Y415	Gene names	C1orf48
Domain Architecture	No domain graphic available
Description	Protein C1orf48.

ATD3A_HUMAN
NC score	0.006547 (rank : 54)	θ value	6.88961 (rank : 46)
Query Neighborhood Hits	52	Target Neighborhood Hits	248	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NVI7, Q8N275, Q96A50	Gene names	ATAD3A
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 3A.

IRF5_MOUSE
NC score	0.005679 (rank : 55)	θ value	5.27518 (rank : 45)
Query Neighborhood Hits	52	Target Neighborhood Hits	49	Shared Neighborhood Hits	2
SwissProt Accessions	P56477	Gene names	Irf5
Domain Architecture
Description	Interferon regulatory factor 5 (IRF-5).

ATAD3_MOUSE
NC score	0.005516 (rank : 56)	θ value	8.99809 (rank : 48)
Query Neighborhood Hits	52	Target Neighborhood Hits	326	Shared Neighborhood Hits	4
SwissProt Accessions	Q925I1, Q3UE74, Q69ZM7, Q8C6C6	Gene names	Atad3, Atad3a, Kiaa1273
Domain Architecture	No domain graphic available
Description	ATPase family AAA domain-containing protein 3 (AAA-ATPase TOB3).

ABCA7_MOUSE
NC score	0.005405 (rank : 57)	θ value	1.81305 (rank : 41)
Query Neighborhood Hits	52	Target Neighborhood Hits	111	Shared Neighborhood Hits	2
SwissProt Accessions	Q91V24, Q9JL36	Gene names	Abca7
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 7.

RNF31_HUMAN
NC score	0.005163 (rank : 58)	θ value	8.99809 (rank : 51)
Query Neighborhood Hits	52	Target Neighborhood Hits	110	Shared Neighborhood Hits	2
SwissProt Accessions	Q96EP0, Q86VI2, Q8TEI0, Q96GB4, Q96NF1, Q9H5F1, Q9NWD2	Gene names	RNF31, ZIBRA
Domain Architecture
Description	RING finger protein 31 (Zinc in-between-RING-finger ubiquitin- associated domain protein).

TEX14_MOUSE
NC score	-0.002891 (rank : 59)	θ value	8.99809 (rank : 52)
Query Neighborhood Hits	52	Target Neighborhood Hits	1333	Shared Neighborhood Hits	2
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).