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Network neighborhood for query Sequence : CIAS1_HUMAN

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CIAS1_HUMAN
SwissProt Accessions	Q96P20, O75434, Q59H68, Q5JQS8, Q5JQS9, Q6TG35, Q8TCW0, Q8TEU9, Q8WXH9	Gene names	CIAS1, NALP3, PYPAF1
Domain Architecture
Description	Cold autoinflammatory syndrome 1 protein (Cryopyrin) (NACHT-, LRR- and PYD-containing protein 3) (PYRIN-containing APAF1-like protein 1) (Angiotensin/vasopressin receptor AII/AVP-like).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CIAS1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	76	Target Neighborhood Hits	76	Shared Neighborhood Hits	76
SwissProt Accessions	Q96P20, O75434, Q59H68, Q5JQS8, Q5JQS9, Q6TG35, Q8TCW0, Q8TEU9, Q8WXH9	Gene names	CIAS1, NALP3, PYPAF1
Domain Architecture
Description	Cold autoinflammatory syndrome 1 protein (Cryopyrin) (NACHT-, LRR- and PYD-containing protein 3) (PYRIN-containing APAF1-like protein 1) (Angiotensin/vasopressin receptor AII/AVP-like).

CIAS1_MOUSE
θ value	0 (rank : 2)	NC score	0.996781 (rank : 2)
Query Neighborhood Hits	76	Target Neighborhood Hits	67	Shared Neighborhood Hits	50
SwissProt Accessions	Q8R4B8, Q6JEL0	Gene names	Cias1, Mmig1, Nalp3, Pypaf1
Domain Architecture
Description	Cold autoinflammatory syndrome 1 protein homolog (PYRIN-containing APAF1-like protein 1) (Mast cell maturation-associated-inducible protein 1) (Cryopyrin).

NAL12_HUMAN
θ value	0 (rank : 3)	NC score	0.987696 (rank : 3)
Query Neighborhood Hits	76	Target Neighborhood Hits	96	Shared Neighborhood Hits	50
SwissProt Accessions	P59046, Q8NEU4, Q9BY26	Gene names	NALP12, PYPAF7, RNO
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 12 (PYRIN-containing APAF1-like protein 7) (Monarch-1) (Regulated by nitric oxide).

NAL14_HUMAN
θ value	6.35588e-163 (rank : 4)	NC score	0.974196 (rank : 4)
Query Neighborhood Hits	76	Target Neighborhood Hits	76	Shared Neighborhood Hits	41
SwissProt Accessions	Q86W24, Q7RTR6	Gene names	NALP14, NOD5
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 14 (Nucleotide-binding oligomerization domain protein 5).

NALP4_HUMAN
θ value	2.689e-137 (rank : 5)	NC score	0.971967 (rank : 5)
Query Neighborhood Hits	76	Target Neighborhood Hits	81	Shared Neighborhood Hits	43
SwissProt Accessions	Q96MN2, Q86W87, Q96AY6	Gene names	NALP4, PAN2, PYPAF4, RNH2
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 4 (PYRIN-containing APAF1-like protein 4) (PAAD and NACHT-containing protein 2) (PYRIN and NACHT- containing protein 2) (Ribonuclease inhibitor 2).

NALP2_HUMAN
θ value	3.28708e-135 (rank : 6)	NC score	0.967306 (rank : 6)
Query Neighborhood Hits	76	Target Neighborhood Hits	65	Shared Neighborhood Hits	42
SwissProt Accessions	Q9NX02, Q53FL5, Q59G09, Q8IXT0, Q9BVN5, Q9H6G6, Q9HAV9, Q9NWK3	Gene names	NALP2, NBS1, PAN1, PYPAF2
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 2 (PYRIN domain and NACHT domain-containing protein 1) (PYRIN-containing APAF1-like protein 2) (Nucleotide-binding site protein 1).

NAL13_HUMAN
θ value	1.33764e-128 (rank : 7)	NC score	0.963862 (rank : 7)
Query Neighborhood Hits	76	Target Neighborhood Hits	93	Shared Neighborhood Hits	41
SwissProt Accessions	Q86W25, Q7RTR5	Gene names	NALP13, NOD14
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 13 (Nucleotide-binding oligomerization domain protein 14).

NALP1_HUMAN
θ value	8.11517e-126 (rank : 8)	NC score	0.925572 (rank : 13)
Query Neighborhood Hits	76	Target Neighborhood Hits	138	Shared Neighborhood Hits	42
SwissProt Accessions	Q9C000, Q9BZZ8, Q9BZZ9, Q9HAV8, Q9UFT4, Q9Y2E0	Gene names	NALP1, CARD7, DEFCAP, KIAA0926, NAC
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 1 (Death effector filament- forming ced-4-like apoptosis protein) (Nucleotide-binding domain and caspase recruitment domain) (Caspase recruitment domain protein 7).

NALP5_HUMAN
θ value	4.16784e-122 (rank : 9)	NC score	0.958051 (rank : 9)
Query Neighborhood Hits	76	Target Neighborhood Hits	88	Shared Neighborhood Hits	42
SwissProt Accessions	P59047, Q86W29	Gene names	NALP5, MATER
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Mater protein homolog).

NALP5_MOUSE
θ value	9.30652e-114 (rank : 10)	NC score	0.889632 (rank : 16)
Query Neighborhood Hits	76	Target Neighborhood Hits	560	Shared Neighborhood Hits	42
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

NALP7_HUMAN
θ value	2.89973e-107 (rank : 11)	NC score	0.960195 (rank : 8)
Query Neighborhood Hits	76	Target Neighborhood Hits	65	Shared Neighborhood Hits	40
SwissProt Accessions	Q8WX94, Q7RTR1	Gene names	NALP7, NOD12, PYPAF3
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 7 (PYRIN-containing APAF1-like protein 3).

NALP6_HUMAN
θ value	3.66817e-102 (rank : 12)	NC score	0.950265 (rank : 10)
Query Neighborhood Hits	76	Target Neighborhood Hits	52	Shared Neighborhood Hits	37
SwissProt Accessions	P59044	Gene names	NALP6, PYPAF5
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 6 (PYRIN-containing APAF1-like protein 5).

NALP6_MOUSE
θ value	6.25694e-102 (rank : 13)	NC score	0.948892 (rank : 11)
Query Neighborhood Hits	76	Target Neighborhood Hits	55	Shared Neighborhood Hits	37
SwissProt Accessions	Q91WS2, Q8K0L4	Gene names	Nalp6, Pypaf5
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 6 (PYRIN-containing APAF1-like protein 5-like).

NAL11_HUMAN
θ value	1.88391e-98 (rank : 14)	NC score	0.946033 (rank : 12)
Query Neighborhood Hits	76	Target Neighborhood Hits	66	Shared Neighborhood Hits	34
SwissProt Accessions	P59045, Q53ZZ0, Q8NBF5	Gene names	NALP11, NOD17, PYPAF6
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 11 (PYRIN-containing APAF1-like protein 6) (Nucleotide-binding oligomerization domain protein 17).

NAL10_HUMAN
θ value	6.27148e-94 (rank : 15)	NC score	0.921601 (rank : 14)
Query Neighborhood Hits	76	Target Neighborhood Hits	55	Shared Neighborhood Hits	33
SwissProt Accessions	Q86W26, Q6JGT0	Gene names	NALP10, NOD8, PYNOD
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 10 (Nucleotide-binding oligomerization domain protein 8).

NAL10_MOUSE
θ value	6.50502e-83 (rank : 16)	NC score	0.915736 (rank : 15)
Query Neighborhood Hits	76	Target Neighborhood Hits	46	Shared Neighborhood Hits	33
SwissProt Accessions	Q8CCN1	Gene names	Nalp10, Pynod
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 10.

RINI_MOUSE
θ value	3.0428e-56 (rank : 17)	NC score	0.869170 (rank : 18)
Query Neighborhood Hits	76	Target Neighborhood Hits	87	Shared Neighborhood Hits	38
SwissProt Accessions	Q91VI7, Q924P4	Gene names	Rnh1, Rnh
Domain Architecture	No domain graphic available
Description	Ribonuclease inhibitor (Ribonuclease/angiogenin inhibitor 1).

RINI_HUMAN
θ value	6.34462e-54 (rank : 18)	NC score	0.872956 (rank : 17)
Query Neighborhood Hits	76	Target Neighborhood Hits	78	Shared Neighborhood Hits	36
SwissProt Accessions	P13489	Gene names	RNH1, PRI, RNH
Domain Architecture
Description	Ribonuclease inhibitor (Ribonuclease/angiogenin inhibitor 1) (RAI) (Placental ribonuclease inhibitor) (RNase inhibitor) (RI).

CAR15_MOUSE
θ value	4.89182e-30 (rank : 19)	NC score	0.758073 (rank : 19)
Query Neighborhood Hits	76	Target Neighborhood Hits	93	Shared Neighborhood Hits	40
SwissProt Accessions	Q8K3Z0	Gene names	Card15, Nod2
Domain Architecture
Description	Caspase recruitment domain-containing protein 15 (Protein Nod2).

CARD4_HUMAN
θ value	5.06226e-27 (rank : 20)	NC score	0.717949 (rank : 22)
Query Neighborhood Hits	76	Target Neighborhood Hits	102	Shared Neighborhood Hits	40
SwissProt Accessions	Q9Y239, Q8IWF5	Gene names	CARD4, NOD1
Domain Architecture
Description	Caspase recruitment domain-containing protein 4 (Protein Nod1).

CARD4_MOUSE
θ value	6.61148e-27 (rank : 21)	NC score	0.719134 (rank : 21)
Query Neighborhood Hits	76	Target Neighborhood Hits	85	Shared Neighborhood Hits	40
SwissProt Accessions	Q8BHB0, Q8BUT6	Gene names	Card4
Domain Architecture
Description	Caspase recruitment domain-containing protein 4.

CAR15_HUMAN
θ value	1.92365e-26 (rank : 22)	NC score	0.743559 (rank : 20)
Query Neighborhood Hits	76	Target Neighborhood Hits	77	Shared Neighborhood Hits	39
SwissProt Accessions	Q9HC29, Q96RH5, Q96RH6, Q96RH8	Gene names	CARD15, IBD1, NOD2
Domain Architecture
Description	Caspase recruitment domain-containing protein 15 (Protein Nod2) (Inflammatory bowel disease protein 1).

C2TA_MOUSE
θ value	8.95645e-16 (rank : 23)	NC score	0.645103 (rank : 23)
Query Neighborhood Hits	76	Target Neighborhood Hits	131	Shared Neighborhood Hits	38
SwissProt Accessions	P79621, O46787, O78036, O78109, Q31115, Q9TPP1	Gene names	Ciita, C2ta, Mhc2ta
Domain Architecture
Description	MHC class II transactivator (CIITA).

C2TA_HUMAN
θ value	5.43371e-13 (rank : 24)	NC score	0.619055 (rank : 24)
Query Neighborhood Hits	76	Target Neighborhood Hits	190	Shared Neighborhood Hits	33
SwissProt Accessions	P33076	Gene names	CIITA, MHC2TA
Domain Architecture
Description	MHC class II transactivator (CIITA).

RGP1_HUMAN
θ value	1.25267e-09 (rank : 25)	NC score	0.391840 (rank : 29)
Query Neighborhood Hits	76	Target Neighborhood Hits	124	Shared Neighborhood Hits	26
SwissProt Accessions	P46060	Gene names	RANGAP1
Domain Architecture
Description	Ran GTPase-activating protein 1.

LRC34_HUMAN
θ value	8.97725e-08 (rank : 26)	NC score	0.545100 (rank : 25)
Query Neighborhood Hits	76	Target Neighborhood Hits	67	Shared Neighborhood Hits	30
SwissProt Accessions	Q8IZ02	Gene names	LRRC34
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 34.

RGP1_MOUSE
θ value	4.45536e-07 (rank : 27)	NC score	0.373298 (rank : 30)
Query Neighborhood Hits	76	Target Neighborhood Hits	105	Shared Neighborhood Hits	26
SwissProt Accessions	P46061, Q60801	Gene names	Rangap1, Fug1
Domain Architecture
Description	Ran GTPase-activating protein 1.

MEFV_MOUSE
θ value	5.81887e-07 (rank : 28)	NC score	0.192048 (rank : 40)
Query Neighborhood Hits	76	Target Neighborhood Hits	236	Shared Neighborhood Hits	15
SwissProt Accessions	Q9JJ26	Gene names	Mefv
Domain Architecture
Description	Pyrin (Marenostrin).

MEFV_HUMAN
θ value	9.92553e-07 (rank : 29)	NC score	0.104522 (rank : 44)
Query Neighborhood Hits	76	Target Neighborhood Hits	431	Shared Neighborhood Hits	15
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

LRC34_MOUSE
θ value	2.88788e-06 (rank : 30)	NC score	0.512051 (rank : 26)
Query Neighborhood Hits	76	Target Neighborhood Hits	58	Shared Neighborhood Hits	30
SwissProt Accessions	Q9DAM1	Gene names	Lrrc34
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 34.

BIRC1_HUMAN
θ value	9.29e-05 (rank : 31)	NC score	0.236951 (rank : 34)
Query Neighborhood Hits	76	Target Neighborhood Hits	61	Shared Neighborhood Hits	29
SwissProt Accessions	Q13075, O75857, Q13730, Q99796	Gene names	BIRC1, NAIP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1 (Neuronal apoptosis inhibitory protein).

BIR1A_MOUSE
θ value	0.000121331 (rank : 32)	NC score	0.218889 (rank : 35)
Query Neighborhood Hits	76	Target Neighborhood Hits	94	Shared Neighborhood Hits	32
SwissProt Accessions	Q9QWK5, Q9JIB5, Q9R017	Gene names	Birc1a, Naip, Naip1
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1a (Neuronal apoptosis inhibitory protein 1).

LRC31_HUMAN
θ value	0.000121331 (rank : 33)	NC score	0.500090 (rank : 27)
Query Neighborhood Hits	76	Target Neighborhood Hits	139	Shared Neighborhood Hits	39
SwissProt Accessions	Q6UY01, Q8N848, Q9H5N5	Gene names	LRRC31
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 31.

CAR12_HUMAN
θ value	0.000786445 (rank : 34)	NC score	0.330275 (rank : 31)
Query Neighborhood Hits	76	Target Neighborhood Hits	132	Shared Neighborhood Hits	40
SwissProt Accessions	Q9NPP4, Q96J81, Q96J82, Q96J83	Gene names	CARD12, CLAN, CLAN1
Domain Architecture
Description	Caspase recruitment domain-containing protein 12 (Ice protease- activating factor) (Ipaf) (CARD, LRR, and NACHT-containing protein) (Clan protein).

LRC45_HUMAN
θ value	0.00390308 (rank : 35)	NC score	0.160071 (rank : 42)
Query Neighborhood Hits	76	Target Neighborhood Hits	933	Shared Neighborhood Hits	36
SwissProt Accessions	Q96CN5	Gene names	LRRC45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

BIR1E_MOUSE
θ value	0.00665767 (rank : 36)	NC score	0.209084 (rank : 37)
Query Neighborhood Hits	76	Target Neighborhood Hits	93	Shared Neighborhood Hits	28
SwissProt Accessions	Q9R016, O09121, O09122, P81703, Q9R029	Gene names	Birc1e, Naip-rs3, Naip5
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1e (Neuronal apoptosis inhibitory protein 5).

PHLPP_HUMAN
θ value	0.0113563 (rank : 37)	NC score	0.040647 (rank : 49)
Query Neighborhood Hits	76	Target Neighborhood Hits	604	Shared Neighborhood Hits	23
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

ASC_MOUSE
θ value	0.0148317 (rank : 38)	NC score	0.319060 (rank : 32)
Query Neighborhood Hits	76	Target Neighborhood Hits	17	Shared Neighborhood Hits	15
SwissProt Accessions	Q9EPB4, Q9D2W9	Gene names	Pycard, Asc
Domain Architecture
Description	Apoptosis-associated speck-like protein containing a CARD (mASC) (PYD and CARD domain-containing protein).

BIR1F_MOUSE
θ value	0.0148317 (rank : 39)	NC score	0.210635 (rank : 36)
Query Neighborhood Hits	76	Target Neighborhood Hits	88	Shared Neighborhood Hits	31
SwissProt Accessions	Q9JIB6, O09121, O09122, P81704	Gene names	Birc1f, Naip-rs4, Naip6
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1f (Neuronal apoptosis inhibitory protein 6).

BIR1B_MOUSE
θ value	0.0193708 (rank : 40)	NC score	0.197412 (rank : 39)
Query Neighborhood Hits	76	Target Neighborhood Hits	93	Shared Neighborhood Hits	29
SwissProt Accessions	Q9QUK4, O09124, Q9R030	Gene names	Birc1b, Naip-rs6, Naip2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1b (Neuronal apoptosis inhibitory protein 2).

BIR1G_MOUSE
θ value	0.0193708 (rank : 41)	NC score	0.202591 (rank : 38)
Query Neighborhood Hits	76	Target Neighborhood Hits	92	Shared Neighborhood Hits	30
SwissProt Accessions	Q9JIB3	Gene names	Birc1g, Naip7
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1g (Neuronal apoptosis inhibitory protein 7).

LRC8D_HUMAN
θ value	0.0193708 (rank : 42)	NC score	0.032774 (rank : 51)
Query Neighborhood Hits	76	Target Neighborhood Hits	282	Shared Neighborhood Hits	23
SwissProt Accessions	Q7L1W4, Q6UWB2, Q9NVW3	Gene names	LRRC8D, LRRC5
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 8D.

LRC8D_MOUSE
θ value	0.0252991 (rank : 43)	NC score	0.029259 (rank : 52)
Query Neighborhood Hits	76	Target Neighborhood Hits	284	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BGR2, Q3UVA9, Q8CI13	Gene names	Lrrc8d, Lrrc5
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 8D.

PHLPP_MOUSE
θ value	0.0431538 (rank : 44)	NC score	0.043312 (rank : 48)
Query Neighborhood Hits	76	Target Neighborhood Hits	394	Shared Neighborhood Hits	23
SwissProt Accessions	Q8CHE4, Q6PCN0, Q8QZU8, Q8R5E5, Q99KL6	Gene names	Phlpp, Kiaa0606, Plekhe1, Scop
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein).

CF154_HUMAN
θ value	0.125558 (rank : 45)	NC score	0.482997 (rank : 28)
Query Neighborhood Hits	76	Target Neighborhood Hits	36	Shared Neighborhood Hits	28
SwissProt Accessions	Q5JTD7	Gene names	C6orf154
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf154.

ASC_HUMAN
θ value	0.163984 (rank : 46)	NC score	0.264723 (rank : 33)
Query Neighborhood Hits	76	Target Neighborhood Hits	18	Shared Neighborhood Hits	14
SwissProt Accessions	Q9ULZ3, Q96D12, Q9BSZ5, Q9HBD0, Q9NXJ8	Gene names	PYCARD, ASC, CARD5, TMS1
Domain Architecture
Description	Apoptosis-associated speck-like protein containing a CARD (hASC) (PYD and CARD domain-containing protein) (Target of methylation-induced silencing 1) (Caspase recruitment domain-containing protein 5).

LRC45_MOUSE
θ value	0.279714 (rank : 47)	NC score	0.170080 (rank : 41)
Query Neighborhood Hits	76	Target Neighborhood Hits	959	Shared Neighborhood Hits	38
SwissProt Accessions	Q8CIM1, Q3U5Z2	Gene names	Lrrc45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

GP1BA_HUMAN
θ value	1.81305 (rank : 48)	NC score	0.025486 (rank : 53)
Query Neighborhood Hits	76	Target Neighborhood Hits	407	Shared Neighborhood Hits	18
SwissProt Accessions	P07359, Q14441, Q16469, Q8N1F3, Q8NG39, Q9HDC7, Q9UEK1, Q9UQS4	Gene names	GP1BA
Domain Architecture
Description	Platelet glycoprotein Ib alpha chain precursor (Glycoprotein Ibalpha) (GP-Ib alpha) (GPIbA) (GPIb-alpha) (Antigen CD42b-alpha) (CD42b antigen) [Contains: Glycocalicin].

LRC15_MOUSE
θ value	1.81305 (rank : 49)	NC score	0.023727 (rank : 54)
Query Neighborhood Hits	76	Target Neighborhood Hits	305	Shared Neighborhood Hits	27
SwissProt Accessions	Q80X72	Gene names	Lrrc15
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 15 precursor.

FLRT1_HUMAN
θ value	2.36792 (rank : 50)	NC score	0.010289 (rank : 66)
Query Neighborhood Hits	76	Target Neighborhood Hits	286	Shared Neighborhood Hits	15
SwissProt Accessions	Q9NZU1	Gene names	FLRT1
Domain Architecture
Description	Leucine-rich repeat transmembrane protein FLRT1 precursor (Fibronectin-like domain-containing leucine-rich transmembrane protein 1).

MYST2_HUMAN
θ value	2.36792 (rank : 51)	NC score	0.011674 (rank : 63)
Query Neighborhood Hits	76	Target Neighborhood Hits	88	Shared Neighborhood Hits	5
SwissProt Accessions	O95251	Gene names	MYST2, HBO1, HBOa
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST2 (EC 2.3.1.48) (MYST protein 2) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2) (Histone acetyltransferase binding to ORC1).

MYST2_MOUSE
θ value	2.36792 (rank : 52)	NC score	0.011674 (rank : 62)
Query Neighborhood Hits	76	Target Neighborhood Hits	87	Shared Neighborhood Hits	5
SwissProt Accessions	Q5SVQ0, Q5SVQ1, Q5SVQ2, Q5SVQ3, Q5SVQ7, Q6PGC6, Q80Y65	Gene names	Myst2, Hbo1
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST2 (EC 2.3.1.48) (MYST protein 2) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2) (Histone acetyltransferase binding to ORC1).

AN32B_HUMAN
θ value	3.0926 (rank : 53)	NC score	0.011555 (rank : 65)
Query Neighborhood Hits	76	Target Neighborhood Hits	243	Shared Neighborhood Hits	10
SwissProt Accessions	Q92688, O00655, P78458, P78459	Gene names	ANP32B, APRIL, PHAPI2
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member B (PHAPI2 protein) (Silver-stainable protein SSP29) (Acidic protein rich in leucines).

ATCAY_HUMAN
θ value	3.0926 (rank : 54)	NC score	0.008358 (rank : 70)
Query Neighborhood Hits	76	Target Neighborhood Hits	18	Shared Neighborhood Hits	2
SwissProt Accessions	Q86WG3, Q8NAQ2, Q8TAQ3, Q96HC6, Q96JF5	Gene names	ATCAY, KIAA1872
Domain Architecture
Description	Caytaxin (Ataxia Cayman type protein) (BNIP-H).

FBXL2_MOUSE
θ value	3.0926 (rank : 55)	NC score	0.009220 (rank : 68)
Query Neighborhood Hits	76	Target Neighborhood Hits	83	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BH16, Q8BXM4	Gene names	Fbxl2, Fbl2
Domain Architecture
Description	F-box/LRR-repeat protein 2 (F-box and leucine-rich repeat protein 2).

ZC3H6_HUMAN
θ value	3.0926 (rank : 56)	NC score	0.011597 (rank : 64)
Query Neighborhood Hits	76	Target Neighborhood Hits	228	Shared Neighborhood Hits	3
SwissProt Accessions	P61129	Gene names	ZC3H6, KIAA2035, ZC3HDC6
Domain Architecture
Description	Zinc finger CCCH domain-containing protein 6.

A20A1_HUMAN
θ value	4.03905 (rank : 57)	NC score	0.001918 (rank : 77)
Query Neighborhood Hits	76	Target Neighborhood Hits	698	Shared Neighborhood Hits	6
SwissProt Accessions	Q5TYW2, Q9H0H6	Gene names	ANKRD20A1, ANKRD20A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A1.

A20A2_HUMAN
θ value	4.03905 (rank : 58)	NC score	0.002018 (rank : 76)
Query Neighborhood Hits	76	Target Neighborhood Hits	716	Shared Neighborhood Hits	6
SwissProt Accessions	Q4UJ75	Gene names	ANKRD20A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A2.

LRC15_HUMAN
θ value	4.03905 (rank : 59)	NC score	0.018669 (rank : 56)
Query Neighborhood Hits	76	Target Neighborhood Hits	305	Shared Neighborhood Hits	20
SwissProt Accessions	Q8TF66, Q7RTN7	Gene names	LRRC15, LIB
Domain Architecture
Description	Leucine-rich repeat-containing protein 15 precursor (hLib).

ODBB_HUMAN
θ value	4.03905 (rank : 60)	NC score	0.012687 (rank : 60)
Query Neighborhood Hits	76	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	P21953	Gene names	BCKDHB
Domain Architecture
Description	2-oxoisovalerate dehydrogenase subunit beta, mitochondrial precursor (EC 1.2.4.4) (Branched-chain alpha-keto acid dehydrogenase E1 component beta chain) (BCKDH E1-beta).

CTBL1_HUMAN
θ value	5.27518 (rank : 61)	NC score	0.012295 (rank : 61)
Query Neighborhood Hits	76	Target Neighborhood Hits	37	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WYA6, Q53HI8, Q5JWZ2, Q5JWZ3, Q5JWZ7, Q5JWZ8, Q8N454, Q8NCL2, Q8TBD6, Q96KD2, Q9H7A5, Q9NQF9, Q9NTX0, Q9Y3M7	Gene names	CTNNBL1, C20orf33
Domain Architecture
Description	Beta-catenin-like protein 1 (Nuclear-associated protein) (NAP) (Testis development protein NYD-SP19).

FMOD_MOUSE
θ value	5.27518 (rank : 62)	NC score	0.009875 (rank : 67)
Query Neighborhood Hits	76	Target Neighborhood Hits	286	Shared Neighborhood Hits	15
SwissProt Accessions	P50608	Gene names	Fmod
Domain Architecture
Description	Fibromodulin precursor (FM) (Collagen-binding 59 kDa protein) (Keratan sulfate proteoglycan fibromodulin) (KSPG fibromodulin).

LRC10_MOUSE
θ value	5.27518 (rank : 63)	NC score	0.016007 (rank : 57)
Query Neighborhood Hits	76	Target Neighborhood Hits	191	Shared Neighborhood Hits	12
SwissProt Accessions	Q8K3W2, Q8BUL2	Gene names	Lrrc10, Hrlrrp
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 10 (Heart-restricted leucine- rich repeat protein).

LRC42_MOUSE
θ value	5.27518 (rank : 64)	NC score	0.039746 (rank : 50)
Query Neighborhood Hits	76	Target Neighborhood Hits	25	Shared Neighborhood Hits	6
SwissProt Accessions	Q8R2U7, Q3TE62, Q9CTP9	Gene names	Lrrc42
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 42.

PIDD_HUMAN
θ value	5.27518 (rank : 65)	NC score	0.021729 (rank : 55)
Query Neighborhood Hits	76	Target Neighborhood Hits	271	Shared Neighborhood Hits	18
SwissProt Accessions	Q9HB75, Q59FD1, Q59H10, Q59HC7, Q7Z4P8, Q8NC89, Q8NDL2, Q96C25, Q9NRE6	Gene names	LRDD, PIDD
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and death domain-containing protein (p53-induced protein with a death domain).

WD51B_HUMAN
θ value	5.27518 (rank : 66)	NC score	-0.000432 (rank : 80)
Query Neighborhood Hits	76	Target Neighborhood Hits	335	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TC44	Gene names	WDR51B
Domain Architecture	No domain graphic available
Description	WD repeat protein 51B.

AN32C_HUMAN
θ value	6.88961 (rank : 67)	NC score	0.014090 (rank : 58)
Query Neighborhood Hits	76	Target Neighborhood Hits	100	Shared Neighborhood Hits	12
SwissProt Accessions	O43423	Gene names	ANP32C, PP32R1
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member C (Phosphoprotein 32-related protein 1) (Tumorigenic protein pp32r1).

CD180_HUMAN
θ value	6.88961 (rank : 68)	NC score	0.008891 (rank : 69)
Query Neighborhood Hits	76	Target Neighborhood Hits	279	Shared Neighborhood Hits	15
SwissProt Accessions	Q99467	Gene names	CD180, LY64, RP105
Domain Architecture
Description	CD180 antigen precursor (Lymphocyte antigen 64) (Radioprotective 105 kDa protein).

CEP35_HUMAN
θ value	6.88961 (rank : 69)	NC score	0.003110 (rank : 73)
Query Neighborhood Hits	76	Target Neighborhood Hits	811	Shared Neighborhood Hits	6
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

CTBL1_MOUSE
θ value	8.99809 (rank : 70)	NC score	0.013405 (rank : 59)
Query Neighborhood Hits	76	Target Neighborhood Hits	34	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CWL8, Q3UL41, Q80X64, Q8VHE3	Gene names	Ctnnbl1
Domain Architecture	No domain graphic available
Description	Beta-catenin-like protein 1 (Nuclear-associated protein) (NAP).

EMR1_HUMAN
θ value	8.99809 (rank : 71)	NC score	-0.000413 (rank : 79)
Query Neighborhood Hits	76	Target Neighborhood Hits	382	Shared Neighborhood Hits	3
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

FBXL2_HUMAN
θ value	8.99809 (rank : 72)	NC score	0.007308 (rank : 71)
Query Neighborhood Hits	76	Target Neighborhood Hits	77	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UKC9, Q9NVQ8, Q9UK27, Q9UKA5, Q9Y3Y9	Gene names	FBXL2, FBL2, FBL3
Domain Architecture
Description	F-box/LRR-repeat protein 2 (F-box and leucine-rich repeat protein 2) (F-box protein FBL2/FBL3).

GNPAT_MOUSE
θ value	8.99809 (rank : 73)	NC score	0.005714 (rank : 72)
Query Neighborhood Hits	76	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	P98192, Q9WUT6	Gene names	Gnpat, Dhapat
Domain Architecture
Description	Dihydroxyacetone phosphate acyltransferase (EC 2.3.1.42) (DHAP-AT) (DAP-AT) (Glycerone-phosphate O-acyltransferase) (Acyl- CoA:dihydroxyacetonephosphateacyltransferase).

NMDE4_HUMAN
θ value	8.99809 (rank : 74)	NC score	0.002586 (rank : 74)
Query Neighborhood Hits	76	Target Neighborhood Hits	133	Shared Neighborhood Hits	3
SwissProt Accessions	O15399	Gene names	GRIN2D
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 4 precursor (N-methyl D- aspartate receptor subtype 2D) (NR2D) (NMDAR2D) (EB11).

NMDE4_MOUSE
θ value	8.99809 (rank : 75)	NC score	0.002516 (rank : 75)
Query Neighborhood Hits	76	Target Neighborhood Hits	158	Shared Neighborhood Hits	3
SwissProt Accessions	Q03391	Gene names	Grin2d
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 4 precursor (N-methyl D- aspartate receptor subtype 2D) (NR2D) (NMDAR2D).

TRPC7_HUMAN
θ value	8.99809 (rank : 76)	NC score	0.001832 (rank : 78)
Query Neighborhood Hits	76	Target Neighborhood Hits	123	Shared Neighborhood Hits	2
SwissProt Accessions	Q9HCX4	Gene names	TRPC7, TRP7
Domain Architecture
Description	Short transient receptor potential channel 7 (TrpC7) (TRP7 protein).

CARD8_HUMAN
θ value	θ > 10 (rank : 77)	NC score	0.125653 (rank : 43)
Query Neighborhood Hits	76	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y2G2, Q6PGP8, Q96P82	Gene names	CARD8, KIAA0955, NDPP1
Domain Architecture
Description	Caspase recruitment domain-containing protein 8 (Apoptotic protein NDPP1) (DACAR) (CARD-inhibitor of NF-kappa-B-activating ligand) (CARDINAL) (Tumor-up-regulated CARD-containing antagonist of CASP9) (TUCAN).

CD14_MOUSE
θ value	θ > 10 (rank : 78)	NC score	0.052860 (rank : 46)
Query Neighborhood Hits	76	Target Neighborhood Hits	104	Shared Neighborhood Hits	10
SwissProt Accessions	P10810	Gene names	Cd14
Domain Architecture
Description	Monocyte differentiation antigen CD14 precursor (Myeloid cell-specific leucine-rich glycoprotein).

LRC14_HUMAN
θ value	θ > 10 (rank : 79)	NC score	0.082781 (rank : 45)
Query Neighborhood Hits	76	Target Neighborhood Hits	57	Shared Neighborhood Hits	16
SwissProt Accessions	Q15048	Gene names	LRRC14, KIAA0014
Domain Architecture
Description	Leucine-rich repeat-containing protein 14.

TMOD2_HUMAN
θ value	θ > 10 (rank : 80)	NC score	0.052608 (rank : 47)
Query Neighborhood Hits	76	Target Neighborhood Hits	29	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NZR1	Gene names	TMOD2, NTMOD
Domain Architecture
Description	Tropomodulin-2 (Neuronal tropomodulin) (N-Tmod).

Hits sorted by NC score

CIAS1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	76	Target Neighborhood Hits	76	Shared Neighborhood Hits	76
SwissProt Accessions	Q96P20, O75434, Q59H68, Q5JQS8, Q5JQS9, Q6TG35, Q8TCW0, Q8TEU9, Q8WXH9	Gene names	CIAS1, NALP3, PYPAF1
Domain Architecture
Description	Cold autoinflammatory syndrome 1 protein (Cryopyrin) (NACHT-, LRR- and PYD-containing protein 3) (PYRIN-containing APAF1-like protein 1) (Angiotensin/vasopressin receptor AII/AVP-like).

CIAS1_MOUSE
NC score	0.996781 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	76	Target Neighborhood Hits	67	Shared Neighborhood Hits	50
SwissProt Accessions	Q8R4B8, Q6JEL0	Gene names	Cias1, Mmig1, Nalp3, Pypaf1
Domain Architecture
Description	Cold autoinflammatory syndrome 1 protein homolog (PYRIN-containing APAF1-like protein 1) (Mast cell maturation-associated-inducible protein 1) (Cryopyrin).

NAL12_HUMAN
NC score	0.987696 (rank : 3)	θ value	0 (rank : 3)
Query Neighborhood Hits	76	Target Neighborhood Hits	96	Shared Neighborhood Hits	50
SwissProt Accessions	P59046, Q8NEU4, Q9BY26	Gene names	NALP12, PYPAF7, RNO
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 12 (PYRIN-containing APAF1-like protein 7) (Monarch-1) (Regulated by nitric oxide).

NAL14_HUMAN
NC score	0.974196 (rank : 4)	θ value	6.35588e-163 (rank : 4)
Query Neighborhood Hits	76	Target Neighborhood Hits	76	Shared Neighborhood Hits	41
SwissProt Accessions	Q86W24, Q7RTR6	Gene names	NALP14, NOD5
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 14 (Nucleotide-binding oligomerization domain protein 5).

NALP4_HUMAN
NC score	0.971967 (rank : 5)	θ value	2.689e-137 (rank : 5)
Query Neighborhood Hits	76	Target Neighborhood Hits	81	Shared Neighborhood Hits	43
SwissProt Accessions	Q96MN2, Q86W87, Q96AY6	Gene names	NALP4, PAN2, PYPAF4, RNH2
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 4 (PYRIN-containing APAF1-like protein 4) (PAAD and NACHT-containing protein 2) (PYRIN and NACHT- containing protein 2) (Ribonuclease inhibitor 2).

NALP2_HUMAN
NC score	0.967306 (rank : 6)	θ value	3.28708e-135 (rank : 6)
Query Neighborhood Hits	76	Target Neighborhood Hits	65	Shared Neighborhood Hits	42
SwissProt Accessions	Q9NX02, Q53FL5, Q59G09, Q8IXT0, Q9BVN5, Q9H6G6, Q9HAV9, Q9NWK3	Gene names	NALP2, NBS1, PAN1, PYPAF2
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 2 (PYRIN domain and NACHT domain-containing protein 1) (PYRIN-containing APAF1-like protein 2) (Nucleotide-binding site protein 1).

NAL13_HUMAN
NC score	0.963862 (rank : 7)	θ value	1.33764e-128 (rank : 7)
Query Neighborhood Hits	76	Target Neighborhood Hits	93	Shared Neighborhood Hits	41
SwissProt Accessions	Q86W25, Q7RTR5	Gene names	NALP13, NOD14
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 13 (Nucleotide-binding oligomerization domain protein 14).

NALP7_HUMAN
NC score	0.960195 (rank : 8)	θ value	2.89973e-107 (rank : 11)
Query Neighborhood Hits	76	Target Neighborhood Hits	65	Shared Neighborhood Hits	40
SwissProt Accessions	Q8WX94, Q7RTR1	Gene names	NALP7, NOD12, PYPAF3
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 7 (PYRIN-containing APAF1-like protein 3).

NALP5_HUMAN
NC score	0.958051 (rank : 9)	θ value	4.16784e-122 (rank : 9)
Query Neighborhood Hits	76	Target Neighborhood Hits	88	Shared Neighborhood Hits	42
SwissProt Accessions	P59047, Q86W29	Gene names	NALP5, MATER
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Mater protein homolog).

NALP6_HUMAN
NC score	0.950265 (rank : 10)	θ value	3.66817e-102 (rank : 12)
Query Neighborhood Hits	76	Target Neighborhood Hits	52	Shared Neighborhood Hits	37
SwissProt Accessions	P59044	Gene names	NALP6, PYPAF5
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 6 (PYRIN-containing APAF1-like protein 5).

NALP6_MOUSE
NC score	0.948892 (rank : 11)	θ value	6.25694e-102 (rank : 13)
Query Neighborhood Hits	76	Target Neighborhood Hits	55	Shared Neighborhood Hits	37
SwissProt Accessions	Q91WS2, Q8K0L4	Gene names	Nalp6, Pypaf5
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 6 (PYRIN-containing APAF1-like protein 5-like).

NAL11_HUMAN
NC score	0.946033 (rank : 12)	θ value	1.88391e-98 (rank : 14)
Query Neighborhood Hits	76	Target Neighborhood Hits	66	Shared Neighborhood Hits	34
SwissProt Accessions	P59045, Q53ZZ0, Q8NBF5	Gene names	NALP11, NOD17, PYPAF6
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 11 (PYRIN-containing APAF1-like protein 6) (Nucleotide-binding oligomerization domain protein 17).

NALP1_HUMAN
NC score	0.925572 (rank : 13)	θ value	8.11517e-126 (rank : 8)
Query Neighborhood Hits	76	Target Neighborhood Hits	138	Shared Neighborhood Hits	42
SwissProt Accessions	Q9C000, Q9BZZ8, Q9BZZ9, Q9HAV8, Q9UFT4, Q9Y2E0	Gene names	NALP1, CARD7, DEFCAP, KIAA0926, NAC
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 1 (Death effector filament- forming ced-4-like apoptosis protein) (Nucleotide-binding domain and caspase recruitment domain) (Caspase recruitment domain protein 7).

NAL10_HUMAN
NC score	0.921601 (rank : 14)	θ value	6.27148e-94 (rank : 15)
Query Neighborhood Hits	76	Target Neighborhood Hits	55	Shared Neighborhood Hits	33
SwissProt Accessions	Q86W26, Q6JGT0	Gene names	NALP10, NOD8, PYNOD
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 10 (Nucleotide-binding oligomerization domain protein 8).

NAL10_MOUSE
NC score	0.915736 (rank : 15)	θ value	6.50502e-83 (rank : 16)
Query Neighborhood Hits	76	Target Neighborhood Hits	46	Shared Neighborhood Hits	33
SwissProt Accessions	Q8CCN1	Gene names	Nalp10, Pynod
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 10.

NALP5_MOUSE
NC score	0.889632 (rank : 16)	θ value	9.30652e-114 (rank : 10)
Query Neighborhood Hits	76	Target Neighborhood Hits	560	Shared Neighborhood Hits	42
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

RINI_HUMAN
NC score	0.872956 (rank : 17)	θ value	6.34462e-54 (rank : 18)
Query Neighborhood Hits	76	Target Neighborhood Hits	78	Shared Neighborhood Hits	36
SwissProt Accessions	P13489	Gene names	RNH1, PRI, RNH
Domain Architecture
Description	Ribonuclease inhibitor (Ribonuclease/angiogenin inhibitor 1) (RAI) (Placental ribonuclease inhibitor) (RNase inhibitor) (RI).

RINI_MOUSE
NC score	0.869170 (rank : 18)	θ value	3.0428e-56 (rank : 17)
Query Neighborhood Hits	76	Target Neighborhood Hits	87	Shared Neighborhood Hits	38
SwissProt Accessions	Q91VI7, Q924P4	Gene names	Rnh1, Rnh
Domain Architecture	No domain graphic available
Description	Ribonuclease inhibitor (Ribonuclease/angiogenin inhibitor 1).

CAR15_MOUSE
NC score	0.758073 (rank : 19)	θ value	4.89182e-30 (rank : 19)
Query Neighborhood Hits	76	Target Neighborhood Hits	93	Shared Neighborhood Hits	40
SwissProt Accessions	Q8K3Z0	Gene names	Card15, Nod2
Domain Architecture
Description	Caspase recruitment domain-containing protein 15 (Protein Nod2).

CAR15_HUMAN
NC score	0.743559 (rank : 20)	θ value	1.92365e-26 (rank : 22)
Query Neighborhood Hits	76	Target Neighborhood Hits	77	Shared Neighborhood Hits	39
SwissProt Accessions	Q9HC29, Q96RH5, Q96RH6, Q96RH8	Gene names	CARD15, IBD1, NOD2
Domain Architecture
Description	Caspase recruitment domain-containing protein 15 (Protein Nod2) (Inflammatory bowel disease protein 1).

CARD4_MOUSE
NC score	0.719134 (rank : 21)	θ value	6.61148e-27 (rank : 21)
Query Neighborhood Hits	76	Target Neighborhood Hits	85	Shared Neighborhood Hits	40
SwissProt Accessions	Q8BHB0, Q8BUT6	Gene names	Card4
Domain Architecture
Description	Caspase recruitment domain-containing protein 4.

CARD4_HUMAN
NC score	0.717949 (rank : 22)	θ value	5.06226e-27 (rank : 20)
Query Neighborhood Hits	76	Target Neighborhood Hits	102	Shared Neighborhood Hits	40
SwissProt Accessions	Q9Y239, Q8IWF5	Gene names	CARD4, NOD1
Domain Architecture
Description	Caspase recruitment domain-containing protein 4 (Protein Nod1).

C2TA_MOUSE
NC score	0.645103 (rank : 23)	θ value	8.95645e-16 (rank : 23)
Query Neighborhood Hits	76	Target Neighborhood Hits	131	Shared Neighborhood Hits	38
SwissProt Accessions	P79621, O46787, O78036, O78109, Q31115, Q9TPP1	Gene names	Ciita, C2ta, Mhc2ta
Domain Architecture
Description	MHC class II transactivator (CIITA).

C2TA_HUMAN
NC score	0.619055 (rank : 24)	θ value	5.43371e-13 (rank : 24)
Query Neighborhood Hits	76	Target Neighborhood Hits	190	Shared Neighborhood Hits	33
SwissProt Accessions	P33076	Gene names	CIITA, MHC2TA
Domain Architecture
Description	MHC class II transactivator (CIITA).

LRC34_HUMAN
NC score	0.545100 (rank : 25)	θ value	8.97725e-08 (rank : 26)
Query Neighborhood Hits	76	Target Neighborhood Hits	67	Shared Neighborhood Hits	30
SwissProt Accessions	Q8IZ02	Gene names	LRRC34
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 34.

LRC34_MOUSE
NC score	0.512051 (rank : 26)	θ value	2.88788e-06 (rank : 30)
Query Neighborhood Hits	76	Target Neighborhood Hits	58	Shared Neighborhood Hits	30
SwissProt Accessions	Q9DAM1	Gene names	Lrrc34
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 34.

LRC31_HUMAN
NC score	0.500090 (rank : 27)	θ value	0.000121331 (rank : 33)
Query Neighborhood Hits	76	Target Neighborhood Hits	139	Shared Neighborhood Hits	39
SwissProt Accessions	Q6UY01, Q8N848, Q9H5N5	Gene names	LRRC31
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 31.

CF154_HUMAN
NC score	0.482997 (rank : 28)	θ value	0.125558 (rank : 45)
Query Neighborhood Hits	76	Target Neighborhood Hits	36	Shared Neighborhood Hits	28
SwissProt Accessions	Q5JTD7	Gene names	C6orf154
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf154.

RGP1_HUMAN
NC score	0.391840 (rank : 29)	θ value	1.25267e-09 (rank : 25)
Query Neighborhood Hits	76	Target Neighborhood Hits	124	Shared Neighborhood Hits	26
SwissProt Accessions	P46060	Gene names	RANGAP1
Domain Architecture
Description	Ran GTPase-activating protein 1.

RGP1_MOUSE
NC score	0.373298 (rank : 30)	θ value	4.45536e-07 (rank : 27)
Query Neighborhood Hits	76	Target Neighborhood Hits	105	Shared Neighborhood Hits	26
SwissProt Accessions	P46061, Q60801	Gene names	Rangap1, Fug1
Domain Architecture
Description	Ran GTPase-activating protein 1.

CAR12_HUMAN
NC score	0.330275 (rank : 31)	θ value	0.000786445 (rank : 34)
Query Neighborhood Hits	76	Target Neighborhood Hits	132	Shared Neighborhood Hits	40
SwissProt Accessions	Q9NPP4, Q96J81, Q96J82, Q96J83	Gene names	CARD12, CLAN, CLAN1
Domain Architecture
Description	Caspase recruitment domain-containing protein 12 (Ice protease- activating factor) (Ipaf) (CARD, LRR, and NACHT-containing protein) (Clan protein).

ASC_MOUSE
NC score	0.319060 (rank : 32)	θ value	0.0148317 (rank : 38)
Query Neighborhood Hits	76	Target Neighborhood Hits	17	Shared Neighborhood Hits	15
SwissProt Accessions	Q9EPB4, Q9D2W9	Gene names	Pycard, Asc
Domain Architecture
Description	Apoptosis-associated speck-like protein containing a CARD (mASC) (PYD and CARD domain-containing protein).

ASC_HUMAN
NC score	0.264723 (rank : 33)	θ value	0.163984 (rank : 46)
Query Neighborhood Hits	76	Target Neighborhood Hits	18	Shared Neighborhood Hits	14
SwissProt Accessions	Q9ULZ3, Q96D12, Q9BSZ5, Q9HBD0, Q9NXJ8	Gene names	PYCARD, ASC, CARD5, TMS1
Domain Architecture
Description	Apoptosis-associated speck-like protein containing a CARD (hASC) (PYD and CARD domain-containing protein) (Target of methylation-induced silencing 1) (Caspase recruitment domain-containing protein 5).

BIRC1_HUMAN
NC score	0.236951 (rank : 34)	θ value	9.29e-05 (rank : 31)
Query Neighborhood Hits	76	Target Neighborhood Hits	61	Shared Neighborhood Hits	29
SwissProt Accessions	Q13075, O75857, Q13730, Q99796	Gene names	BIRC1, NAIP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1 (Neuronal apoptosis inhibitory protein).

BIR1A_MOUSE
NC score	0.218889 (rank : 35)	θ value	0.000121331 (rank : 32)
Query Neighborhood Hits	76	Target Neighborhood Hits	94	Shared Neighborhood Hits	32
SwissProt Accessions	Q9QWK5, Q9JIB5, Q9R017	Gene names	Birc1a, Naip, Naip1
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1a (Neuronal apoptosis inhibitory protein 1).

BIR1F_MOUSE
NC score	0.210635 (rank : 36)	θ value	0.0148317 (rank : 39)
Query Neighborhood Hits	76	Target Neighborhood Hits	88	Shared Neighborhood Hits	31
SwissProt Accessions	Q9JIB6, O09121, O09122, P81704	Gene names	Birc1f, Naip-rs4, Naip6
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1f (Neuronal apoptosis inhibitory protein 6).

BIR1E_MOUSE
NC score	0.209084 (rank : 37)	θ value	0.00665767 (rank : 36)
Query Neighborhood Hits	76	Target Neighborhood Hits	93	Shared Neighborhood Hits	28
SwissProt Accessions	Q9R016, O09121, O09122, P81703, Q9R029	Gene names	Birc1e, Naip-rs3, Naip5
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1e (Neuronal apoptosis inhibitory protein 5).

BIR1G_MOUSE
NC score	0.202591 (rank : 38)	θ value	0.0193708 (rank : 41)
Query Neighborhood Hits	76	Target Neighborhood Hits	92	Shared Neighborhood Hits	30
SwissProt Accessions	Q9JIB3	Gene names	Birc1g, Naip7
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1g (Neuronal apoptosis inhibitory protein 7).

BIR1B_MOUSE
NC score	0.197412 (rank : 39)	θ value	0.0193708 (rank : 40)
Query Neighborhood Hits	76	Target Neighborhood Hits	93	Shared Neighborhood Hits	29
SwissProt Accessions	Q9QUK4, O09124, Q9R030	Gene names	Birc1b, Naip-rs6, Naip2
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 1b (Neuronal apoptosis inhibitory protein 2).

MEFV_MOUSE
NC score	0.192048 (rank : 40)	θ value	5.81887e-07 (rank : 28)
Query Neighborhood Hits	76	Target Neighborhood Hits	236	Shared Neighborhood Hits	15
SwissProt Accessions	Q9JJ26	Gene names	Mefv
Domain Architecture
Description	Pyrin (Marenostrin).

LRC45_MOUSE
NC score	0.170080 (rank : 41)	θ value	0.279714 (rank : 47)
Query Neighborhood Hits	76	Target Neighborhood Hits	959	Shared Neighborhood Hits	38
SwissProt Accessions	Q8CIM1, Q3U5Z2	Gene names	Lrrc45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

LRC45_HUMAN
NC score	0.160071 (rank : 42)	θ value	0.00390308 (rank : 35)
Query Neighborhood Hits	76	Target Neighborhood Hits	933	Shared Neighborhood Hits	36
SwissProt Accessions	Q96CN5	Gene names	LRRC45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

CARD8_HUMAN
NC score	0.125653 (rank : 43)	θ value	θ > 10 (rank : 77)
Query Neighborhood Hits	76	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y2G2, Q6PGP8, Q96P82	Gene names	CARD8, KIAA0955, NDPP1
Domain Architecture
Description	Caspase recruitment domain-containing protein 8 (Apoptotic protein NDPP1) (DACAR) (CARD-inhibitor of NF-kappa-B-activating ligand) (CARDINAL) (Tumor-up-regulated CARD-containing antagonist of CASP9) (TUCAN).

MEFV_HUMAN
NC score	0.104522 (rank : 44)	θ value	9.92553e-07 (rank : 29)
Query Neighborhood Hits	76	Target Neighborhood Hits	431	Shared Neighborhood Hits	15
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

LRC14_HUMAN
NC score	0.082781 (rank : 45)	θ value	θ > 10 (rank : 79)
Query Neighborhood Hits	76	Target Neighborhood Hits	57	Shared Neighborhood Hits	16
SwissProt Accessions	Q15048	Gene names	LRRC14, KIAA0014
Domain Architecture
Description	Leucine-rich repeat-containing protein 14.

CD14_MOUSE
NC score	0.052860 (rank : 46)	θ value	θ > 10 (rank : 78)
Query Neighborhood Hits	76	Target Neighborhood Hits	104	Shared Neighborhood Hits	10
SwissProt Accessions	P10810	Gene names	Cd14
Domain Architecture
Description	Monocyte differentiation antigen CD14 precursor (Myeloid cell-specific leucine-rich glycoprotein).

TMOD2_HUMAN
NC score	0.052608 (rank : 47)	θ value	θ > 10 (rank : 80)
Query Neighborhood Hits	76	Target Neighborhood Hits	29	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NZR1	Gene names	TMOD2, NTMOD
Domain Architecture
Description	Tropomodulin-2 (Neuronal tropomodulin) (N-Tmod).

PHLPP_MOUSE
NC score	0.043312 (rank : 48)	θ value	0.0431538 (rank : 44)
Query Neighborhood Hits	76	Target Neighborhood Hits	394	Shared Neighborhood Hits	23
SwissProt Accessions	Q8CHE4, Q6PCN0, Q8QZU8, Q8R5E5, Q99KL6	Gene names	Phlpp, Kiaa0606, Plekhe1, Scop
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein).

PHLPP_HUMAN
NC score	0.040647 (rank : 49)	θ value	0.0113563 (rank : 37)
Query Neighborhood Hits	76	Target Neighborhood Hits	604	Shared Neighborhood Hits	23
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

LRC42_MOUSE
NC score	0.039746 (rank : 50)	θ value	5.27518 (rank : 64)
Query Neighborhood Hits	76	Target Neighborhood Hits	25	Shared Neighborhood Hits	6
SwissProt Accessions	Q8R2U7, Q3TE62, Q9CTP9	Gene names	Lrrc42
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 42.

LRC8D_HUMAN
NC score	0.032774 (rank : 51)	θ value	0.0193708 (rank : 42)
Query Neighborhood Hits	76	Target Neighborhood Hits	282	Shared Neighborhood Hits	23
SwissProt Accessions	Q7L1W4, Q6UWB2, Q9NVW3	Gene names	LRRC8D, LRRC5
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 8D.

LRC8D_MOUSE
NC score	0.029259 (rank : 52)	θ value	0.0252991 (rank : 43)
Query Neighborhood Hits	76	Target Neighborhood Hits	284	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BGR2, Q3UVA9, Q8CI13	Gene names	Lrrc8d, Lrrc5
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 8D.

GP1BA_HUMAN
NC score	0.025486 (rank : 53)	θ value	1.81305 (rank : 48)
Query Neighborhood Hits	76	Target Neighborhood Hits	407	Shared Neighborhood Hits	18
SwissProt Accessions	P07359, Q14441, Q16469, Q8N1F3, Q8NG39, Q9HDC7, Q9UEK1, Q9UQS4	Gene names	GP1BA
Domain Architecture
Description	Platelet glycoprotein Ib alpha chain precursor (Glycoprotein Ibalpha) (GP-Ib alpha) (GPIbA) (GPIb-alpha) (Antigen CD42b-alpha) (CD42b antigen) [Contains: Glycocalicin].

LRC15_MOUSE
NC score	0.023727 (rank : 54)	θ value	1.81305 (rank : 49)
Query Neighborhood Hits	76	Target Neighborhood Hits	305	Shared Neighborhood Hits	27
SwissProt Accessions	Q80X72	Gene names	Lrrc15
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 15 precursor.

PIDD_HUMAN
NC score	0.021729 (rank : 55)	θ value	5.27518 (rank : 65)
Query Neighborhood Hits	76	Target Neighborhood Hits	271	Shared Neighborhood Hits	18
SwissProt Accessions	Q9HB75, Q59FD1, Q59H10, Q59HC7, Q7Z4P8, Q8NC89, Q8NDL2, Q96C25, Q9NRE6	Gene names	LRDD, PIDD
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and death domain-containing protein (p53-induced protein with a death domain).

LRC15_HUMAN
NC score	0.018669 (rank : 56)	θ value	4.03905 (rank : 59)
Query Neighborhood Hits	76	Target Neighborhood Hits	305	Shared Neighborhood Hits	20
SwissProt Accessions	Q8TF66, Q7RTN7	Gene names	LRRC15, LIB
Domain Architecture
Description	Leucine-rich repeat-containing protein 15 precursor (hLib).

LRC10_MOUSE
NC score	0.016007 (rank : 57)	θ value	5.27518 (rank : 63)
Query Neighborhood Hits	76	Target Neighborhood Hits	191	Shared Neighborhood Hits	12
SwissProt Accessions	Q8K3W2, Q8BUL2	Gene names	Lrrc10, Hrlrrp
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 10 (Heart-restricted leucine- rich repeat protein).

AN32C_HUMAN
NC score	0.014090 (rank : 58)	θ value	6.88961 (rank : 67)
Query Neighborhood Hits	76	Target Neighborhood Hits	100	Shared Neighborhood Hits	12
SwissProt Accessions	O43423	Gene names	ANP32C, PP32R1
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member C (Phosphoprotein 32-related protein 1) (Tumorigenic protein pp32r1).

CTBL1_MOUSE
NC score	0.013405 (rank : 59)	θ value	8.99809 (rank : 70)
Query Neighborhood Hits	76	Target Neighborhood Hits	34	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CWL8, Q3UL41, Q80X64, Q8VHE3	Gene names	Ctnnbl1
Domain Architecture	No domain graphic available
Description	Beta-catenin-like protein 1 (Nuclear-associated protein) (NAP).

ODBB_HUMAN
NC score	0.012687 (rank : 60)	θ value	4.03905 (rank : 60)
Query Neighborhood Hits	76	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	P21953	Gene names	BCKDHB
Domain Architecture
Description	2-oxoisovalerate dehydrogenase subunit beta, mitochondrial precursor (EC 1.2.4.4) (Branched-chain alpha-keto acid dehydrogenase E1 component beta chain) (BCKDH E1-beta).

CTBL1_HUMAN
NC score	0.012295 (rank : 61)	θ value	5.27518 (rank : 61)
Query Neighborhood Hits	76	Target Neighborhood Hits	37	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WYA6, Q53HI8, Q5JWZ2, Q5JWZ3, Q5JWZ7, Q5JWZ8, Q8N454, Q8NCL2, Q8TBD6, Q96KD2, Q9H7A5, Q9NQF9, Q9NTX0, Q9Y3M7	Gene names	CTNNBL1, C20orf33
Domain Architecture
Description	Beta-catenin-like protein 1 (Nuclear-associated protein) (NAP) (Testis development protein NYD-SP19).

MYST2_MOUSE
NC score	0.011674 (rank : 62)	θ value	2.36792 (rank : 52)
Query Neighborhood Hits	76	Target Neighborhood Hits	87	Shared Neighborhood Hits	5
SwissProt Accessions	Q5SVQ0, Q5SVQ1, Q5SVQ2, Q5SVQ3, Q5SVQ7, Q6PGC6, Q80Y65	Gene names	Myst2, Hbo1
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST2 (EC 2.3.1.48) (MYST protein 2) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2) (Histone acetyltransferase binding to ORC1).

MYST2_HUMAN
NC score	0.011674 (rank : 63)	θ value	2.36792 (rank : 51)
Query Neighborhood Hits	76	Target Neighborhood Hits	88	Shared Neighborhood Hits	5
SwissProt Accessions	O95251	Gene names	MYST2, HBO1, HBOa
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST2 (EC 2.3.1.48) (MYST protein 2) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2) (Histone acetyltransferase binding to ORC1).

ZC3H6_HUMAN
NC score	0.011597 (rank : 64)	θ value	3.0926 (rank : 56)
Query Neighborhood Hits	76	Target Neighborhood Hits	228	Shared Neighborhood Hits	3
SwissProt Accessions	P61129	Gene names	ZC3H6, KIAA2035, ZC3HDC6
Domain Architecture
Description	Zinc finger CCCH domain-containing protein 6.

AN32B_HUMAN
NC score	0.011555 (rank : 65)	θ value	3.0926 (rank : 53)
Query Neighborhood Hits	76	Target Neighborhood Hits	243	Shared Neighborhood Hits	10
SwissProt Accessions	Q92688, O00655, P78458, P78459	Gene names	ANP32B, APRIL, PHAPI2
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member B (PHAPI2 protein) (Silver-stainable protein SSP29) (Acidic protein rich in leucines).

FLRT1_HUMAN
NC score	0.010289 (rank : 66)	θ value	2.36792 (rank : 50)
Query Neighborhood Hits	76	Target Neighborhood Hits	286	Shared Neighborhood Hits	15
SwissProt Accessions	Q9NZU1	Gene names	FLRT1
Domain Architecture
Description	Leucine-rich repeat transmembrane protein FLRT1 precursor (Fibronectin-like domain-containing leucine-rich transmembrane protein 1).

FMOD_MOUSE
NC score	0.009875 (rank : 67)	θ value	5.27518 (rank : 62)
Query Neighborhood Hits	76	Target Neighborhood Hits	286	Shared Neighborhood Hits	15
SwissProt Accessions	P50608	Gene names	Fmod
Domain Architecture
Description	Fibromodulin precursor (FM) (Collagen-binding 59 kDa protein) (Keratan sulfate proteoglycan fibromodulin) (KSPG fibromodulin).

FBXL2_MOUSE
NC score	0.009220 (rank : 68)	θ value	3.0926 (rank : 55)
Query Neighborhood Hits	76	Target Neighborhood Hits	83	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BH16, Q8BXM4	Gene names	Fbxl2, Fbl2
Domain Architecture
Description	F-box/LRR-repeat protein 2 (F-box and leucine-rich repeat protein 2).

CD180_HUMAN
NC score	0.008891 (rank : 69)	θ value	6.88961 (rank : 68)
Query Neighborhood Hits	76	Target Neighborhood Hits	279	Shared Neighborhood Hits	15
SwissProt Accessions	Q99467	Gene names	CD180, LY64, RP105
Domain Architecture
Description	CD180 antigen precursor (Lymphocyte antigen 64) (Radioprotective 105 kDa protein).

ATCAY_HUMAN
NC score	0.008358 (rank : 70)	θ value	3.0926 (rank : 54)
Query Neighborhood Hits	76	Target Neighborhood Hits	18	Shared Neighborhood Hits	2
SwissProt Accessions	Q86WG3, Q8NAQ2, Q8TAQ3, Q96HC6, Q96JF5	Gene names	ATCAY, KIAA1872
Domain Architecture
Description	Caytaxin (Ataxia Cayman type protein) (BNIP-H).

FBXL2_HUMAN
NC score	0.007308 (rank : 71)	θ value	8.99809 (rank : 72)
Query Neighborhood Hits	76	Target Neighborhood Hits	77	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UKC9, Q9NVQ8, Q9UK27, Q9UKA5, Q9Y3Y9	Gene names	FBXL2, FBL2, FBL3
Domain Architecture
Description	F-box/LRR-repeat protein 2 (F-box and leucine-rich repeat protein 2) (F-box protein FBL2/FBL3).

GNPAT_MOUSE
NC score	0.005714 (rank : 72)	θ value	8.99809 (rank : 73)
Query Neighborhood Hits	76	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	P98192, Q9WUT6	Gene names	Gnpat, Dhapat
Domain Architecture
Description	Dihydroxyacetone phosphate acyltransferase (EC 2.3.1.42) (DHAP-AT) (DAP-AT) (Glycerone-phosphate O-acyltransferase) (Acyl- CoA:dihydroxyacetonephosphateacyltransferase).

CEP35_HUMAN
NC score	0.003110 (rank : 73)	θ value	6.88961 (rank : 69)
Query Neighborhood Hits	76	Target Neighborhood Hits	811	Shared Neighborhood Hits	6
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

NMDE4_HUMAN
NC score	0.002586 (rank : 74)	θ value	8.99809 (rank : 74)
Query Neighborhood Hits	76	Target Neighborhood Hits	133	Shared Neighborhood Hits	3
SwissProt Accessions	O15399	Gene names	GRIN2D
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 4 precursor (N-methyl D- aspartate receptor subtype 2D) (NR2D) (NMDAR2D) (EB11).

NMDE4_MOUSE
NC score	0.002516 (rank : 75)	θ value	8.99809 (rank : 75)
Query Neighborhood Hits	76	Target Neighborhood Hits	158	Shared Neighborhood Hits	3
SwissProt Accessions	Q03391	Gene names	Grin2d
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 4 precursor (N-methyl D- aspartate receptor subtype 2D) (NR2D) (NMDAR2D).

A20A2_HUMAN
NC score	0.002018 (rank : 76)	θ value	4.03905 (rank : 58)
Query Neighborhood Hits	76	Target Neighborhood Hits	716	Shared Neighborhood Hits	6
SwissProt Accessions	Q4UJ75	Gene names	ANKRD20A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A2.

A20A1_HUMAN
NC score	0.001918 (rank : 77)	θ value	4.03905 (rank : 57)
Query Neighborhood Hits	76	Target Neighborhood Hits	698	Shared Neighborhood Hits	6
SwissProt Accessions	Q5TYW2, Q9H0H6	Gene names	ANKRD20A1, ANKRD20A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A1.

TRPC7_HUMAN
NC score	0.001832 (rank : 78)	θ value	8.99809 (rank : 76)
Query Neighborhood Hits	76	Target Neighborhood Hits	123	Shared Neighborhood Hits	2
SwissProt Accessions	Q9HCX4	Gene names	TRPC7, TRP7
Domain Architecture
Description	Short transient receptor potential channel 7 (TrpC7) (TRP7 protein).

EMR1_HUMAN
NC score	-0.000413 (rank : 79)	θ value	8.99809 (rank : 71)
Query Neighborhood Hits	76	Target Neighborhood Hits	382	Shared Neighborhood Hits	3
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

WD51B_HUMAN
NC score	-0.000432 (rank : 80)	θ value	5.27518 (rank : 66)
Query Neighborhood Hits	76	Target Neighborhood Hits	335	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TC44	Gene names	WDR51B
Domain Architecture	No domain graphic available
Description	WD repeat protein 51B.