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Network neighborhood for query Sequence : BMS1_HUMAN

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BMS1_HUMAN
SwissProt Accessions	Q14692, Q86XJ9	Gene names	BMS1L, KIAA0187
Domain Architecture
Description	Ribosome biogenesis protein BMS1 homolog.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

BMS1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	109	Target Neighborhood Hits	109	Shared Neighborhood Hits	109
SwissProt Accessions	Q14692, Q86XJ9	Gene names	BMS1L, KIAA0187
Domain Architecture
Description	Ribosome biogenesis protein BMS1 homolog.

LEO1_HUMAN
θ value	4.1701e-05 (rank : 2)	NC score	0.160363 (rank : 2)
Query Neighborhood Hits	109	Target Neighborhood Hits	958	Shared Neighborhood Hits	39
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

LEO1_MOUSE
θ value	9.29e-05 (rank : 3)	NC score	0.154736 (rank : 3)
Query Neighborhood Hits	109	Target Neighborhood Hits	946	Shared Neighborhood Hits	40
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

YTDC1_HUMAN
θ value	0.00869519 (rank : 4)	NC score	0.146579 (rank : 4)
Query Neighborhood Hits	109	Target Neighborhood Hits	458	Shared Neighborhood Hits	35
SwissProt Accessions	Q96MU7, Q7Z622, Q8TF35	Gene names	YTHDC1, KIAA1966, YT521
Domain Architecture
Description	YTH domain-containing protein 1 (Putative splicing factor YT521).

RIOK2_HUMAN
θ value	0.0193708 (rank : 5)	NC score	0.107250 (rank : 6)
Query Neighborhood Hits	109	Target Neighborhood Hits	125	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BVS4, Q9NUT0	Gene names	RIOK2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase RIO2 (EC 2.7.11.1) (RIO kinase 2).

RPGR_MOUSE
θ value	0.0431538 (rank : 6)	NC score	0.075564 (rank : 30)
Query Neighborhood Hits	109	Target Neighborhood Hits	281	Shared Neighborhood Hits	22
SwissProt Accessions	Q9R0X5, O88408, Q9CU92	Gene names	Rpgr
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator (mRpgr).

DSPP_MOUSE
θ value	0.0736092 (rank : 7)	NC score	0.123743 (rank : 5)
Query Neighborhood Hits	109	Target Neighborhood Hits	491	Shared Neighborhood Hits	26
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

ITSN1_HUMAN
θ value	0.0736092 (rank : 8)	NC score	0.051136 (rank : 74)
Query Neighborhood Hits	109	Target Neighborhood Hits	1757	Shared Neighborhood Hits	43
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

RIF1_HUMAN
θ value	0.0736092 (rank : 9)	NC score	0.106709 (rank : 7)
Query Neighborhood Hits	109	Target Neighborhood Hits	320	Shared Neighborhood Hits	28
SwissProt Accessions	Q5UIP0, Q5H9R3, Q5UIP2, Q66YK6, Q6PRU2, Q8TE94, Q99772, Q9H830, Q9H9B9, Q9NVP5, Q9Y4R4	Gene names	RIF1
Domain Architecture	No domain graphic available
Description	Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog).

CCD93_HUMAN
θ value	0.163984 (rank : 10)	NC score	0.059192 (rank : 55)
Query Neighborhood Hits	109	Target Neighborhood Hits	600	Shared Neighborhood Hits	22
SwissProt Accessions	Q567U6, Q4LE78, Q53TJ2, Q8TBX5, Q9H6R5, Q9NV15	Gene names	CCDC93
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 93.

RAI14_MOUSE
θ value	0.163984 (rank : 11)	NC score	0.037569 (rank : 103)
Query Neighborhood Hits	109	Target Neighborhood Hits	1505	Shared Neighborhood Hits	42
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

SET_HUMAN
θ value	0.163984 (rank : 12)	NC score	0.102878 (rank : 8)
Query Neighborhood Hits	109	Target Neighborhood Hits	71	Shared Neighborhood Hits	15
SwissProt Accessions	Q01105, Q15541, Q5VXV1	Gene names	SET
Domain Architecture
Description	Protein SET (Phosphatase 2A inhibitor I2PP2A) (I-2PP2A) (Template- activating factor I) (TAF-I) (HLA-DR-associated protein II) (PHAPII) (Inhibitor of granzyme A-activated DNase) (IGAAD).

SET_MOUSE
θ value	0.163984 (rank : 13)	NC score	0.100224 (rank : 9)
Query Neighborhood Hits	109	Target Neighborhood Hits	61	Shared Neighborhood Hits	14
SwissProt Accessions	Q9EQU5, Q9CY82, Q9D0A9, Q9Z181	Gene names	Set
Domain Architecture
Description	Protein SET (Phosphatase 2A inhibitor I2PP2A) (I-2PP2A) (Template- activating factor I) (TAF-I).

GOGB1_HUMAN
θ value	0.21417 (rank : 14)	NC score	0.047713 (rank : 83)
Query Neighborhood Hits	109	Target Neighborhood Hits	2297	Shared Neighborhood Hits	64
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

TCAL5_HUMAN
θ value	0.21417 (rank : 15)	NC score	0.067556 (rank : 40)
Query Neighborhood Hits	109	Target Neighborhood Hits	806	Shared Neighborhood Hits	29
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

BAZ1B_HUMAN
θ value	0.279714 (rank : 16)	NC score	0.052536 (rank : 70)
Query Neighborhood Hits	109	Target Neighborhood Hits	701	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

EP15R_HUMAN
θ value	0.279714 (rank : 17)	NC score	0.066258 (rank : 43)
Query Neighborhood Hits	109	Target Neighborhood Hits	1083	Shared Neighborhood Hits	41
SwissProt Accessions	Q9UBC2	Gene names	EPS15L1, EPS15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R).

EP15R_MOUSE
θ value	0.365318 (rank : 18)	NC score	0.064693 (rank : 46)
Query Neighborhood Hits	109	Target Neighborhood Hits	1135	Shared Neighborhood Hits	35
SwissProt Accessions	Q60902, Q8CB60, Q8CB70, Q91WH8	Gene names	Eps15l1, Eps15-rs, Eps15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs).

MLL3_HUMAN
θ value	0.365318 (rank : 19)	NC score	0.041980 (rank : 94)
Query Neighborhood Hits	109	Target Neighborhood Hits	1644	Shared Neighborhood Hits	32
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

BTAF1_HUMAN
θ value	0.47712 (rank : 20)	NC score	0.033447 (rank : 112)
Query Neighborhood Hits	109	Target Neighborhood Hits	97	Shared Neighborhood Hits	4
SwissProt Accessions	O14981, O43578	Gene names	BTAF1, TAF172
Domain Architecture
Description	TATA-binding protein-associated factor 172 (EC 3.6.1.-) (ATP-dependent helicase BTAF1) (TBP-associated factor 172) (TAF-172) (TAF(II)170) (B- TFIID transcription factor-associated 170 kDa subunit).

ATRX_MOUSE
θ value	0.62314 (rank : 21)	NC score	0.069912 (rank : 38)
Query Neighborhood Hits	109	Target Neighborhood Hits	682	Shared Neighborhood Hits	43
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

BFSP2_HUMAN
θ value	0.62314 (rank : 22)	NC score	0.022156 (rank : 122)
Query Neighborhood Hits	109	Target Neighborhood Hits	348	Shared Neighborhood Hits	11
SwissProt Accessions	Q13515, Q9HBW5	Gene names	BFSP2
Domain Architecture
Description	Phakinin (Beaded filament structural protein 2) (Lens fiber cell beaded filament protein CP 49) (CP49) (49 kDa cytoskeletal protein) (CP 47) (CP47) (Lens intermediate filament-like light) (LIFL-L).

SMC1A_HUMAN
θ value	0.62314 (rank : 23)	NC score	0.053834 (rank : 67)
Query Neighborhood Hits	109	Target Neighborhood Hits	1346	Shared Neighborhood Hits	47
SwissProt Accessions	Q14683, O14995, Q16351	Gene names	SMC1L1, DXS423E, KIAA0178, SB1.8, SMC1
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Sb1.8).

SMC1A_MOUSE
θ value	0.62314 (rank : 24)	NC score	0.052346 (rank : 71)
Query Neighborhood Hits	109	Target Neighborhood Hits	1384	Shared Neighborhood Hits	47
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

STX1C_HUMAN
θ value	0.62314 (rank : 25)	NC score	0.083953 (rank : 15)
Query Neighborhood Hits	109	Target Neighborhood Hits	270	Shared Neighborhood Hits	21
SwissProt Accessions	P61266	Gene names	STX1B2
Domain Architecture
Description	Syntaxin-1B2.

STX1C_MOUSE
θ value	0.62314 (rank : 26)	NC score	0.083953 (rank : 16)
Query Neighborhood Hits	109	Target Neighborhood Hits	270	Shared Neighborhood Hits	21
SwissProt Accessions	P61264, P32853	Gene names	Stx1b2, Stx1b
Domain Architecture
Description	Syntaxin-1B2 (Syntaxin 1B).

VPS72_MOUSE
θ value	0.62314 (rank : 27)	NC score	0.087887 (rank : 11)
Query Neighborhood Hits	109	Target Neighborhood Hits	286	Shared Neighborhood Hits	16
SwissProt Accessions	Q62481, Q3U2N4, Q810A9, Q99K81	Gene names	Vps72, Tcfl1, Yl1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

FANCJ_MOUSE
θ value	0.813845 (rank : 28)	NC score	0.042329 (rank : 93)
Query Neighborhood Hits	109	Target Neighborhood Hits	57	Shared Neighborhood Hits	2
SwissProt Accessions	Q5SXJ3, Q8BJQ8, Q8BKI6	Gene names	Brip1, Bach1, Fancj
Domain Architecture	No domain graphic available
Description	Fanconi anemia group J protein homolog (EC 3.6.1.-) (ATP-dependent RNA helicase BRIP1) (Protein FACJ) (BRCA1-interacting protein C-terminal helicase 1) (BRCA1-interacting protein 1) (BRCA1-associated C-terminal helicase 1).

NAL14_HUMAN
θ value	0.813845 (rank : 29)	NC score	0.027917 (rank : 118)
Query Neighborhood Hits	109	Target Neighborhood Hits	76	Shared Neighborhood Hits	3
SwissProt Accessions	Q86W24, Q7RTR6	Gene names	NALP14, NOD5
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 14 (Nucleotide-binding oligomerization domain protein 5).

NCOA7_HUMAN
θ value	0.813845 (rank : 30)	NC score	0.045586 (rank : 87)
Query Neighborhood Hits	109	Target Neighborhood Hits	160	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NI08, Q3LID6, Q4G0V1, Q5TF95, Q6IPQ4, Q6NE83, Q86T89, Q8N1W4	Gene names	NCOA7, ERAP140, ESNA1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 7 (140 kDa estrogen receptor-associated protein) (Estrogen nuclear receptor coactivator 1).

UBP42_HUMAN
θ value	0.813845 (rank : 31)	NC score	0.031065 (rank : 114)
Query Neighborhood Hits	109	Target Neighborhood Hits	445	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

VPS72_HUMAN
θ value	0.813845 (rank : 32)	NC score	0.087111 (rank : 12)
Query Neighborhood Hits	109	Target Neighborhood Hits	274	Shared Neighborhood Hits	16
SwissProt Accessions	Q15906, Q53GJ2, Q5U0R4	Gene names	VPS72, TCFL1, YL1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

IPP2_MOUSE
θ value	1.06291 (rank : 33)	NC score	0.067310 (rank : 41)
Query Neighborhood Hits	109	Target Neighborhood Hits	49	Shared Neighborhood Hits	4
SwissProt Accessions	Q9DCL8, Q3UD25, Q8C1A6	Gene names	Ppp1r2
Domain Architecture	No domain graphic available
Description	Protein phosphatase inhibitor 2 (IPP-2).

SEL1L_MOUSE
θ value	1.06291 (rank : 34)	NC score	0.040882 (rank : 97)
Query Neighborhood Hits	109	Target Neighborhood Hits	62	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z2G6, Q9DBD8	Gene names	Sel1l, Sel1h
Domain Architecture
Description	Sel-1 homolog precursor (Suppressor of lin-12-like protein) (Sel-1L).

SPAG1_MOUSE
θ value	1.06291 (rank : 35)	NC score	0.034603 (rank : 107)
Query Neighborhood Hits	109	Target Neighborhood Hits	218	Shared Neighborhood Hits	7
SwissProt Accessions	Q80ZX8, Q8CCK7, Q9QZJ3, Q9QZJ4	Gene names	Spag1, Tpis
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 1 (Infertility-related sperm protein Spag-1) (TPR-containing protein involved in spermatogenesis) (TPIS).

CT151_HUMAN
θ value	1.38821 (rank : 36)	NC score	0.062746 (rank : 48)
Query Neighborhood Hits	109	Target Neighborhood Hits	382	Shared Neighborhood Hits	16
SwissProt Accessions	Q8NC74, Q8N4Z9, Q9BR75, Q9H0Y9	Gene names	C20orf151
Domain Architecture
Description	Uncharacterized protein C20orf151.

OSBL8_HUMAN
θ value	1.38821 (rank : 37)	NC score	0.040723 (rank : 98)
Query Neighborhood Hits	109	Target Neighborhood Hits	289	Shared Neighborhood Hits	23
SwissProt Accessions	Q9BZF1, Q8WXP8, Q9P277	Gene names	OSBPL8, KIAA1451, ORP8, OSBP10
Domain Architecture
Description	Oxysterol-binding protein-related protein 8 (OSBP-related protein 8) (ORP-8).

REPS1_HUMAN
θ value	1.38821 (rank : 38)	NC score	0.075683 (rank : 29)
Query Neighborhood Hits	109	Target Neighborhood Hits	205	Shared Neighborhood Hits	15
SwissProt Accessions	Q96D71, Q8NDR7, Q8WU62, Q9BXY9	Gene names	REPS1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1).

WDR67_HUMAN
θ value	1.38821 (rank : 39)	NC score	0.040948 (rank : 96)
Query Neighborhood Hits	109	Target Neighborhood Hits	782	Shared Neighborhood Hits	17
SwissProt Accessions	Q96DN5, Q3MIR6, Q8TBP9	Gene names	WDR67
Domain Architecture	No domain graphic available
Description	WD repeat protein 67.

ERIC1_HUMAN
θ value	1.81305 (rank : 40)	NC score	0.084173 (rank : 14)
Query Neighborhood Hits	109	Target Neighborhood Hits	364	Shared Neighborhood Hits	18
SwissProt Accessions	Q86X53, Q9P063	Gene names	ERICH1
Domain Architecture	No domain graphic available
Description	Glutamate-rich protein 1.

REPS1_MOUSE
θ value	1.81305 (rank : 41)	NC score	0.072980 (rank : 34)
Query Neighborhood Hits	109	Target Neighborhood Hits	204	Shared Neighborhood Hits	13
SwissProt Accessions	O54916, Q8C9J9, Q99LR8	Gene names	Reps1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1).

RIF1_MOUSE
θ value	1.81305 (rank : 42)	NC score	0.083021 (rank : 19)
Query Neighborhood Hits	109	Target Neighborhood Hits	315	Shared Neighborhood Hits	18
SwissProt Accessions	Q6PR54, Q6T8D9, Q7TPD8, Q8BTU2, Q8C408, Q9CS77	Gene names	Rif1
Domain Architecture	No domain graphic available
Description	Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog) (mRif1).

SASH1_HUMAN
θ value	1.81305 (rank : 43)	NC score	0.035336 (rank : 105)
Query Neighborhood Hits	109	Target Neighborhood Hits	292	Shared Neighborhood Hits	9
SwissProt Accessions	O94885, Q8TAI0, Q9H7R7	Gene names	SASH1, KIAA0790, PEPE1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1 (Proline-glutamate repeat- containing protein).

SELB_HUMAN
θ value	1.81305 (rank : 44)	NC score	0.048889 (rank : 81)
Query Neighborhood Hits	109	Target Neighborhood Hits	37	Shared Neighborhood Hits	3
SwissProt Accessions	P57772	Gene names	EEFSEC, SELB
Domain Architecture
Description	Selenocysteine-specific elongation factor (Elongation factor sec) (Eukaryotic elongation factor, selenocysteine-tRNA-specific).

SELB_MOUSE
θ value	1.81305 (rank : 45)	NC score	0.047700 (rank : 84)
Query Neighborhood Hits	109	Target Neighborhood Hits	38	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JHW4	Gene names	Eefsec, Selb
Domain Architecture
Description	Selenocysteine-specific elongation factor (Elongation factor sec) (Eukaryotic elongation factor, selenocysteine-tRNA-specific) (mSelB).

STX1B_HUMAN
θ value	1.81305 (rank : 46)	NC score	0.079701 (rank : 21)
Query Neighborhood Hits	109	Target Neighborhood Hits	252	Shared Neighborhood Hits	19
SwissProt Accessions	Q15531	Gene names	STX1B1, STX1B
Domain Architecture
Description	Syntaxin-1B1 (Syntaxin 1B).

SYNE2_HUMAN
θ value	1.81305 (rank : 47)	NC score	0.034391 (rank : 108)
Query Neighborhood Hits	109	Target Neighborhood Hits	1323	Shared Neighborhood Hits	38
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

TP53B_MOUSE
θ value	1.81305 (rank : 48)	NC score	0.054746 (rank : 61)
Query Neighborhood Hits	109	Target Neighborhood Hits	644	Shared Neighborhood Hits	24
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

TTC1_HUMAN
θ value	1.81305 (rank : 49)	NC score	0.039397 (rank : 100)
Query Neighborhood Hits	109	Target Neighborhood Hits	417	Shared Neighborhood Hits	17
SwissProt Accessions	Q99614, Q9BVT3	Gene names	TTC1, TPR1
Domain Architecture
Description	Tetratricopeptide repeat protein 1 (TPR repeat protein 1).

BPTF_HUMAN
θ value	2.36792 (rank : 50)	NC score	0.053614 (rank : 68)
Query Neighborhood Hits	109	Target Neighborhood Hits	786	Shared Neighborhood Hits	41
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

HECD1_HUMAN
θ value	2.36792 (rank : 51)	NC score	0.020892 (rank : 124)
Query Neighborhood Hits	109	Target Neighborhood Hits	371	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ULT8, Q6P445, Q86VJ1, Q96F34, Q9UFZ7	Gene names	HECTD1, KIAA1131
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase HECTD1 (HECT domain-containing protein 1) (E3 ligase for inhibin receptor) (EULIR).

ROCK2_MOUSE
θ value	2.36792 (rank : 52)	NC score	0.018315 (rank : 127)
Query Neighborhood Hits	109	Target Neighborhood Hits	2072	Shared Neighborhood Hits	44
SwissProt Accessions	P70336, Q8BR64, Q8CBR0	Gene names	Rock2
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2).

SEC63_HUMAN
θ value	2.36792 (rank : 53)	NC score	0.051359 (rank : 73)
Query Neighborhood Hits	109	Target Neighborhood Hits	586	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UGP8, O95380, Q86VS9, Q8IWL0, Q9NTE0	Gene names	SEC63, SEC63L
Domain Architecture
Description	Translocation protein SEC63 homolog.

STX1A_HUMAN
θ value	2.36792 (rank : 54)	NC score	0.079392 (rank : 24)
Query Neighborhood Hits	109	Target Neighborhood Hits	266	Shared Neighborhood Hits	21
SwissProt Accessions	Q16623, O15447, O15448, Q12936, Q9BPZ6	Gene names	STX1A, STX1
Domain Architecture
Description	Syntaxin-1A (Neuron-specific antigen HPC-1).

STX1A_MOUSE
θ value	2.36792 (rank : 55)	NC score	0.079581 (rank : 22)
Query Neighborhood Hits	109	Target Neighborhood Hits	261	Shared Neighborhood Hits	21
SwissProt Accessions	O35526	Gene names	Stx1a
Domain Architecture
Description	Syntaxin-1A (Neuron-specific antigen HPC-1).

STX3_HUMAN
θ value	2.36792 (rank : 56)	NC score	0.078355 (rank : 26)
Query Neighborhood Hits	109	Target Neighborhood Hits	211	Shared Neighborhood Hits	19
SwissProt Accessions	Q13277, O43750, O43751, Q15360	Gene names	STX3, STX3A
Domain Architecture
Description	Syntaxin-3.

STX3_MOUSE
θ value	2.36792 (rank : 57)	NC score	0.079472 (rank : 23)
Query Neighborhood Hits	109	Target Neighborhood Hits	212	Shared Neighborhood Hits	19
SwissProt Accessions	Q64704	Gene names	Stx3, Stx3a
Domain Architecture
Description	Syntaxin-3.

TOIP1_HUMAN
θ value	2.36792 (rank : 58)	NC score	0.040399 (rank : 99)
Query Neighborhood Hits	109	Target Neighborhood Hits	58	Shared Neighborhood Hits	7
SwissProt Accessions	Q5JTV8, Q5JTV6, Q8IZ65, Q9H8Y6, Q9HAJ1, Q9NV52, Q9Y3X5	Gene names	TOR1AIP1
Domain Architecture	No domain graphic available
Description	Torsin-1A-interacting protein 1.

BRD8_MOUSE
θ value	3.0926 (rank : 59)	NC score	0.044956 (rank : 89)
Query Neighborhood Hits	109	Target Neighborhood Hits	422	Shared Neighborhood Hits	21
SwissProt Accessions	Q8R3B7, Q8C049, Q8R583, Q8VDP0	Gene names	Brd8
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8.

E41L1_HUMAN
θ value	3.0926 (rank : 60)	NC score	0.014329 (rank : 133)
Query Neighborhood Hits	109	Target Neighborhood Hits	180	Shared Neighborhood Hits	11
SwissProt Accessions	Q9H4G0, O15046, Q4VXN4	Gene names	EPB41L1, KIAA0338
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).

GLE1_MOUSE
θ value	3.0926 (rank : 61)	NC score	0.043964 (rank : 92)
Query Neighborhood Hits	109	Target Neighborhood Hits	504	Shared Neighborhood Hits	21
SwissProt Accessions	Q8R322, Q3TT10, Q3TU23, Q3UD65, Q8BT16, Q9D4A6	Gene names	Gle1l
Domain Architecture	No domain graphic available
Description	Nucleoporin GLE1 (GLE1-like protein).

IWS1_HUMAN
θ value	3.0926 (rank : 62)	NC score	0.077194 (rank : 28)
Query Neighborhood Hits	109	Target Neighborhood Hits	1241	Shared Neighborhood Hits	56
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

OPTN_HUMAN
θ value	3.0926 (rank : 63)	NC score	0.041913 (rank : 95)
Query Neighborhood Hits	109	Target Neighborhood Hits	827	Shared Neighborhood Hits	32
SwissProt Accessions	Q96CV9, Q5T672, Q5T673, Q5T674, Q5T675, Q7LDL9, Q8N562, Q9UET9, Q9UEV4, Q9Y218	Gene names	OPTN, FIP2, GLC1E, NRP
Domain Architecture	No domain graphic available
Description	Optineurin (Optic neuropathy-inducing protein) (E3-14.7K-interacting protein) (FIP-2) (Huntingtin-interacting protein HYPL) (NEMO-related protein) (Transcription factor IIIA-interacting protein) (TFIIIA- IntP).

SDCG1_MOUSE
θ value	3.0926 (rank : 64)	NC score	0.043990 (rank : 91)
Query Neighborhood Hits	109	Target Neighborhood Hits	168	Shared Neighborhood Hits	13
SwissProt Accessions	Q8CCP0, Q66JX6, Q8C9R6, Q8CA65, Q8JZT9, Q8R072, Q9CW30, Q9CYB8, Q9D4A9	Gene names	Sdccag1
Domain Architecture
Description	Serologically defined colon cancer antigen 1.

TAOK1_MOUSE
θ value	3.0926 (rank : 65)	NC score	0.013052 (rank : 134)
Query Neighborhood Hits	109	Target Neighborhood Hits	1720	Shared Neighborhood Hits	32
SwissProt Accessions	Q5F2E8, Q69ZL2, Q8JZX2, Q91VG7	Gene names	Taok1, Kiaa1361
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Thousand and one amino acid protein 1).

UB7I1_MOUSE
θ value	3.0926 (rank : 66)	NC score	0.028424 (rank : 117)
Query Neighborhood Hits	109	Target Neighborhood Hits	206	Shared Neighborhood Hits	4
SwissProt Accessions	P58283, Q3U493, Q3UE56, Q3UGM3, Q68FN0, Q6P1H8, Q6PWY5, Q8BN27, Q8C1U3	Gene names	Ubce7ip1, Triad3, Uip83, Zin
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase TRIAD3 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (UbcM4-interacting protein 83) (Triad domain- containing protein 3).

VAV_HUMAN
θ value	3.0926 (rank : 67)	NC score	0.016454 (rank : 132)
Query Neighborhood Hits	109	Target Neighborhood Hits	452	Shared Neighborhood Hits	9
SwissProt Accessions	P15498, Q15860	Gene names	VAV1, VAV
Domain Architecture
Description	Proto-oncogene vav.

CL026_HUMAN
θ value	4.03905 (rank : 68)	NC score	0.032156 (rank : 113)
Query Neighborhood Hits	109	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N6Q8, Q9H5Y3	Gene names	C12orf26
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C12orf26.

IWS1_MOUSE
θ value	4.03905 (rank : 69)	NC score	0.075047 (rank : 31)
Query Neighborhood Hits	109	Target Neighborhood Hits	1258	Shared Neighborhood Hits	50
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

LAMB2_MOUSE
θ value	4.03905 (rank : 70)	NC score	0.009191 (rank : 138)
Query Neighborhood Hits	109	Target Neighborhood Hits	722	Shared Neighborhood Hits	11
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

NC6IP_MOUSE
θ value	4.03905 (rank : 71)	NC score	0.050093 (rank : 79)
Query Neighborhood Hits	109	Target Neighborhood Hits	161	Shared Neighborhood Hits	11
SwissProt Accessions	Q923W1, Q6DI60, Q6PEA7, Q8R0W9	Gene names	Ncoa6ip, Pimt
Domain Architecture	No domain graphic available
Description	Putative RNA methyltransferase NCOA6IP (EC 2.1.1.-) (Nuclear receptor coactivator 6-interacting protein) (PRIP-interacting protein with methyltransferase motif) (PIPMT) (PIMT).

WRN_MOUSE
θ value	4.03905 (rank : 72)	NC score	0.025312 (rank : 120)
Query Neighborhood Hits	109	Target Neighborhood Hits	295	Shared Neighborhood Hits	18
SwissProt Accessions	O09053, O09050, Q9JKD4, Q9Z241, Q9Z242	Gene names	Wrn
Domain Architecture
Description	Werner syndrome ATP-dependent helicase homolog (EC 3.6.1.-).

CASC5_HUMAN
θ value	5.27518 (rank : 73)	NC score	0.039363 (rank : 101)
Query Neighborhood Hits	109	Target Neighborhood Hits	376	Shared Neighborhood Hits	20
SwissProt Accessions	Q8NG31, Q8NHE1, Q8WXA6, Q9HCK2, Q9NR92	Gene names	CASC5, KIAA1570
Domain Architecture	No domain graphic available
Description	Protein CASC5 (Cancer susceptibility candidate gene 5 protein) (ALL1- fused gene from chromosome 15q14) (AF15q14) (D40/AF15q14 protein).

CIA30_MOUSE
θ value	5.27518 (rank : 74)	NC score	0.030714 (rank : 115)
Query Neighborhood Hits	109	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CWX2, Q8VEI8	Gene names	Ndufaf1, Cia30
Domain Architecture	No domain graphic available
Description	Complex I intermediate-associated protein 30, mitochondrial precursor (NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 1).

CING_MOUSE
θ value	5.27518 (rank : 75)	NC score	0.033955 (rank : 110)
Query Neighborhood Hits	109	Target Neighborhood Hits	1432	Shared Neighborhood Hits	40
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

DNJA1_HUMAN
θ value	5.27518 (rank : 76)	NC score	0.017728 (rank : 129)
Query Neighborhood Hits	109	Target Neighborhood Hits	84	Shared Neighborhood Hits	4
SwissProt Accessions	P31689	Gene names	DNAJA1, DNAJ2, HDJ2, HSJ2, HSPF4
Domain Architecture
Description	DnaJ homolog subfamily A member 1 (Heat shock 40 kDa protein 4) (DnaJ protein homolog 2) (HSJ-2) (HSDJ).

DNJA1_MOUSE
θ value	5.27518 (rank : 77)	NC score	0.017839 (rank : 128)
Query Neighborhood Hits	109	Target Neighborhood Hits	83	Shared Neighborhood Hits	4
SwissProt Accessions	P63037, P54102	Gene names	Dnaja1, Dnaj2, Hsj2, Hspf4
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily A member 1 (Heat shock 40 kDa protein 4) (DnaJ protein homolog 2) (HSJ-2).

K0423_MOUSE
θ value	5.27518 (rank : 78)	NC score	0.027839 (rank : 119)
Query Neighborhood Hits	109	Target Neighborhood Hits	115	Shared Neighborhood Hits	7
SwissProt Accessions	Q6A070	Gene names	Kiaa0423
Domain Architecture	No domain graphic available
Description	Protein KIAA0423.

LAP2_HUMAN
θ value	5.27518 (rank : 79)	NC score	0.008806 (rank : 139)
Query Neighborhood Hits	109	Target Neighborhood Hits	499	Shared Neighborhood Hits	8
SwissProt Accessions	Q96RT1, Q86W38, Q9NR18, Q9NW48, Q9ULJ5	Gene names	ERBB2IP, ERBIN, KIAA1225, LAP2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

NALP7_HUMAN
θ value	5.27518 (rank : 80)	NC score	0.021475 (rank : 123)
Query Neighborhood Hits	109	Target Neighborhood Hits	65	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WX94, Q7RTR1	Gene names	NALP7, NOD12, PYPAF3
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 7 (PYRIN-containing APAF1-like protein 3).

SPB13_HUMAN
θ value	5.27518 (rank : 81)	NC score	0.006823 (rank : 141)
Query Neighborhood Hits	109	Target Neighborhood Hits	97	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UIV8, Q9HCX1, Q9UBW1, Q9UKG0	Gene names	SERPINB13, PI13
Domain Architecture
Description	Serpin B13 (Hurpin) (HaCaT UV-repressible serpin) (Protease inhibitor 13) (Headpin).

TAOK1_HUMAN
θ value	5.27518 (rank : 82)	NC score	0.012215 (rank : 135)
Query Neighborhood Hits	109	Target Neighborhood Hits	1734	Shared Neighborhood Hits	33
SwissProt Accessions	Q7L7X3, Q96L75, Q9H2K7, Q9H7S5, Q9P2I6	Gene names	TAOK1, KIAA1361, MAP3K16
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Thousand and one amino acid protein 1) (STE20-like kinase PSK2) (Kinase from chicken homolog B) (hKFC-B).

AKAP8_MOUSE
θ value	6.88961 (rank : 83)	NC score	0.019777 (rank : 125)
Query Neighborhood Hits	109	Target Neighborhood Hits	76	Shared Neighborhood Hits	4
SwissProt Accessions	Q9DBR0, Q9R0L8	Gene names	Akap8, Akap95
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 8 (A-kinase anchor protein 95 kDa) (AKAP 95).

CASQ1_HUMAN
θ value	6.88961 (rank : 84)	NC score	0.017403 (rank : 131)
Query Neighborhood Hits	109	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	P31415, Q8TBW7	Gene names	CASQ1, CASQ
Domain Architecture
Description	Calsequestrin-1 precursor (Calsequestrin, skeletal muscle isoform) (Calmitin).

CCD55_MOUSE
θ value	6.88961 (rank : 85)	NC score	0.061405 (rank : 52)
Query Neighborhood Hits	109	Target Neighborhood Hits	519	Shared Neighborhood Hits	33
SwissProt Accessions	Q5NCR9	Gene names	Ccdc55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

CT2NL_HUMAN
θ value	6.88961 (rank : 86)	NC score	0.034866 (rank : 106)
Query Neighborhood Hits	109	Target Neighborhood Hits	1059	Shared Neighborhood Hits	32
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

ESCO2_MOUSE
θ value	6.88961 (rank : 87)	NC score	0.019714 (rank : 126)
Query Neighborhood Hits	109	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CIB9, Q3UMT6, Q6IQX5, Q8BNG9, Q8BQF8, Q9CRI8	Gene names	Esco2
Domain Architecture	No domain graphic available
Description	N-acetyltransferase ESCO2 (EC 2.3.1.-) (Establishment of cohesion 1 homolog 2) (ECO1 homolog 2).

ITSN1_MOUSE
θ value	6.88961 (rank : 88)	NC score	0.044042 (rank : 90)
Query Neighborhood Hits	109	Target Neighborhood Hits	1669	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

PRP4_MOUSE
θ value	6.88961 (rank : 89)	NC score	0.006081 (rank : 142)
Query Neighborhood Hits	109	Target Neighborhood Hits	308	Shared Neighborhood Hits	3
SwissProt Accessions	Q9DAW6	Gene names	Prpf4
Domain Architecture	No domain graphic available
Description	U4/U6 small nuclear ribonucleoprotein Prp4 (U4/U6 snRNP 60 kDa protein) (WD splicing factor Prp4).

REST_MOUSE
θ value	6.88961 (rank : 90)	NC score	0.030663 (rank : 116)
Query Neighborhood Hits	109	Target Neighborhood Hits	1506	Shared Neighborhood Hits	41
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

SELO_HUMAN
θ value	6.88961 (rank : 91)	NC score	0.023211 (rank : 121)
Query Neighborhood Hits	109	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BVL4, Q8WUI0	Gene names	SELO
Domain Architecture
Description	Selenoprotein O.

SEMG2_HUMAN
θ value	6.88961 (rank : 92)	NC score	0.045273 (rank : 88)
Query Neighborhood Hits	109	Target Neighborhood Hits	251	Shared Neighborhood Hits	17
SwissProt Accessions	Q02383, Q6X2M6	Gene names	SEMG2
Domain Architecture
Description	Semenogelin-2 precursor (Semenogelin II) (SGII).

CC47_MOUSE
θ value	8.99809 (rank : 93)	NC score	0.038854 (rank : 102)
Query Neighborhood Hits	109	Target Neighborhood Hits	245	Shared Neighborhood Hits	18
SwissProt Accessions	Q9D024, Q3TSB5, Q3V1S7, Q8C5D9, Q920S6	Gene names	Ccdc47, Asp4
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 47 precursor (Adipocyte-specific protein 4).

CJ068_HUMAN
θ value	8.99809 (rank : 94)	NC score	0.036670 (rank : 104)
Query Neighborhood Hits	109	Target Neighborhood Hits	316	Shared Neighborhood Hits	21
SwissProt Accessions	Q9H943, Q8N7T7	Gene names	C10orf68
Domain Architecture	No domain graphic available
Description	Protein C10orf68.

CT2NL_MOUSE
θ value	8.99809 (rank : 95)	NC score	0.034109 (rank : 109)
Query Neighborhood Hits	109	Target Neighborhood Hits	902	Shared Neighborhood Hits	25
SwissProt Accessions	Q99LJ0, Q6ZPR0, Q8BSV1	Gene names	Cttnbp2nl, Kiaa1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

FA21C_HUMAN
θ value	8.99809 (rank : 96)	NC score	0.052903 (rank : 69)
Query Neighborhood Hits	109	Target Neighborhood Hits	194	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y4E1, Q5SQU4, Q5SQU5, Q7L521, Q9UG79	Gene names	FAM21C, KIAA0592
Domain Architecture	No domain graphic available
Description	Protein FAM21C.

GOGA4_MOUSE
θ value	8.99809 (rank : 97)	NC score	0.033622 (rank : 111)
Query Neighborhood Hits	109	Target Neighborhood Hits	1939	Shared Neighborhood Hits	52
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

HTSF1_MOUSE
θ value	8.99809 (rank : 98)	NC score	0.083781 (rank : 18)
Query Neighborhood Hits	109	Target Neighborhood Hits	425	Shared Neighborhood Hits	37
SwissProt Accessions	Q8BGC0, Q1WWK0, Q9CT41, Q9DAU3	Gene names	Htatsf1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 homolog.

LIMA1_HUMAN
θ value	8.99809 (rank : 99)	NC score	0.017624 (rank : 130)
Query Neighborhood Hits	109	Target Neighborhood Hits	309	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UHB6, Q2TAN7, Q9BVF2, Q9H8J1, Q9HBN5, Q9NX96, Q9NXC3, Q9NXU6, Q9P0H8, Q9UHB5	Gene names	LIMA1, EPLIN, SREBP3
Domain Architecture
Description	LIM domain and actin-binding protein 1 (Epithelial protein lost in neoplasm).

MYST4_HUMAN
θ value	8.99809 (rank : 100)	NC score	0.045691 (rank : 86)
Query Neighborhood Hits	109	Target Neighborhood Hits	671	Shared Neighborhood Hits	42
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

PEPP2_HUMAN
θ value	8.99809 (rank : 101)	NC score	0.007241 (rank : 140)
Query Neighborhood Hits	109	Target Neighborhood Hits	316	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BQY4, Q9BR00	Gene names	PEPP2, THG1
Domain Architecture
Description	Paired-like homeobox protein PEPP-2 (Testis homeobox gene 1).

RB39B_HUMAN
θ value	8.99809 (rank : 102)	NC score	0.003556 (rank : 144)
Query Neighborhood Hits	109	Target Neighborhood Hits	279	Shared Neighborhood Hits	3
SwissProt Accessions	Q96DA2, Q5JT79, Q8NEX3	Gene names	RAB39B
Domain Architecture
Description	Ras-related protein Rab-39B.

RB39B_MOUSE
θ value	8.99809 (rank : 103)	NC score	0.003595 (rank : 143)
Query Neighborhood Hits	109	Target Neighborhood Hits	277	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BHC1, Q3TUJ3	Gene names	Rab39b
Domain Architecture
Description	Ras-related protein Rab-39B.

SPRL1_MOUSE
θ value	8.99809 (rank : 104)	NC score	0.047538 (rank : 85)
Query Neighborhood Hits	109	Target Neighborhood Hits	403	Shared Neighborhood Hits	24
SwissProt Accessions	P70663, P97810, Q99L82	Gene names	Sparcl1, Ecm2, Sc1
Domain Architecture
Description	SPARC-like protein 1 precursor (Matrix glycoprotein Sc1) (Extracellular matrix protein 2).

SRGP2_HUMAN
θ value	8.99809 (rank : 105)	NC score	0.011551 (rank : 137)
Query Neighborhood Hits	109	Target Neighborhood Hits	331	Shared Neighborhood Hits	8
SwissProt Accessions	O43295, Q8IX13, Q8IZV8	Gene names	SRGAP3, ARHGAP14, KIAA0411, MEGAP, SRGAP2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Mental disorder- associated GAP) (Rho-GTPase-activating protein 14).

STX2_HUMAN
θ value	8.99809 (rank : 106)	NC score	0.071516 (rank : 37)
Query Neighborhood Hits	109	Target Neighborhood Hits	158	Shared Neighborhood Hits	15
SwissProt Accessions	P32856, Q86VW8	Gene names	STX2, EPIM
Domain Architecture
Description	Syntaxin-2 (Epimorphin).

UBP25_MOUSE
θ value	8.99809 (rank : 107)	NC score	0.012143 (rank : 136)
Query Neighborhood Hits	109	Target Neighborhood Hits	116	Shared Neighborhood Hits	5
SwissProt Accessions	P57080, Q80ZT9	Gene names	Usp25
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 25 (EC 3.1.2.15) (Ubiquitin thioesterase 25) (Ubiquitin-specific-processing protease 25) (Deubiquitinating enzyme 25) (mUSP25).

WBP11_HUMAN
θ value	8.99809 (rank : 108)	NC score	0.048327 (rank : 82)
Query Neighborhood Hits	109	Target Neighborhood Hits	354	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

WBP11_MOUSE
θ value	8.99809 (rank : 109)	NC score	0.050855 (rank : 76)
Query Neighborhood Hits	109	Target Neighborhood Hits	362	Shared Neighborhood Hits	21
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

ATRX_HUMAN
θ value	θ > 10 (rank : 110)	NC score	0.060668 (rank : 54)
Query Neighborhood Hits	109	Target Neighborhood Hits	842	Shared Neighborhood Hits	46
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

CALD1_HUMAN
θ value	θ > 10 (rank : 111)	NC score	0.057865 (rank : 58)
Query Neighborhood Hits	109	Target Neighborhood Hits	959	Shared Neighborhood Hits	50
SwissProt Accessions	Q05682, Q13978, Q13979, Q14741, Q14742	Gene names	CALD1, CAD, CDM
Domain Architecture
Description	Caldesmon (CDM).

CCAR1_HUMAN
θ value	θ > 10 (rank : 112)	NC score	0.050510 (rank : 77)
Query Neighborhood Hits	109	Target Neighborhood Hits	444	Shared Neighborhood Hits	41
SwissProt Accessions	Q8IX12, Q32NE3, Q5VUP6, Q6PIZ0, Q6X935, Q9H8N4, Q9NVA7, Q9NVQ0, Q9NWM6	Gene names	CCAR1, CARP1, DIS
Domain Architecture	No domain graphic available
Description	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1) (Death inducer with SAP domain).

CYLC1_HUMAN
θ value	θ > 10 (rank : 113)	NC score	0.061881 (rank : 51)
Query Neighborhood Hits	109	Target Neighborhood Hits	408	Shared Neighborhood Hits	30
SwissProt Accessions	P35663, Q5JQQ9	Gene names	CYLC1, CYL, CYL1
Domain Architecture	No domain graphic available
Description	Cylicin-1 (Cylicin I) (Multiple-band polypeptide I).

CYLC2_HUMAN
θ value	θ > 10 (rank : 114)	NC score	0.068286 (rank : 39)
Query Neighborhood Hits	109	Target Neighborhood Hits	223	Shared Neighborhood Hits	23
SwissProt Accessions	Q14093	Gene names	CYLC2, CYL2
Domain Architecture	No domain graphic available
Description	Cylicin-2 (Cylicin II) (Multiple-band polypeptide II).

DMP1_HUMAN
θ value	θ > 10 (rank : 115)	NC score	0.072293 (rank : 36)
Query Neighborhood Hits	109	Target Neighborhood Hits	491	Shared Neighborhood Hits	37
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

DMP1_MOUSE
θ value	θ > 10 (rank : 116)	NC score	0.077734 (rank : 27)
Query Neighborhood Hits	109	Target Neighborhood Hits	498	Shared Neighborhood Hits	33
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

DSPP_HUMAN
θ value	θ > 10 (rank : 117)	NC score	0.082877 (rank : 20)
Query Neighborhood Hits	109	Target Neighborhood Hits	645	Shared Neighborhood Hits	31
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

HIRP3_HUMAN
θ value	θ > 10 (rank : 118)	NC score	0.054193 (rank : 65)
Query Neighborhood Hits	109	Target Neighborhood Hits	323	Shared Neighborhood Hits	32
SwissProt Accessions	Q9BW71, O75707, O75708	Gene names	HIRIP3
Domain Architecture	No domain graphic available
Description	HIRA-interacting protein 3.

HTSF1_HUMAN
θ value	θ > 10 (rank : 119)	NC score	0.064941 (rank : 45)
Query Neighborhood Hits	109	Target Neighborhood Hits	408	Shared Neighborhood Hits	35
SwissProt Accessions	O43719, Q59G06, Q99730	Gene names	HTATSF1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 (Tat-SF1).

IF2P_HUMAN
θ value	θ > 10 (rank : 120)	NC score	0.066864 (rank : 42)
Query Neighborhood Hits	109	Target Neighborhood Hits	889	Shared Neighborhood Hits	56
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

MDN1_HUMAN
θ value	θ > 10 (rank : 121)	NC score	0.051929 (rank : 72)
Query Neighborhood Hits	109	Target Neighborhood Hits	662	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

MFAP1_MOUSE
θ value	θ > 10 (rank : 122)	NC score	0.055248 (rank : 60)
Query Neighborhood Hits	109	Target Neighborhood Hits	353	Shared Neighborhood Hits	36
SwissProt Accessions	Q9CQU1, Q3TU29, Q8CCL1, Q9CSJ5	Gene names	Mfap1
Domain Architecture	No domain graphic available
Description	Microfibrillar-associated protein 1.

NSBP1_HUMAN
θ value	θ > 10 (rank : 123)	NC score	0.083878 (rank : 17)
Query Neighborhood Hits	109	Target Neighborhood Hits	251	Shared Neighborhood Hits	29
SwissProt Accessions	P82970	Gene names	NSBP1
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1.

NSBP1_MOUSE
θ value	θ > 10 (rank : 124)	NC score	0.065894 (rank : 44)
Query Neighborhood Hits	109	Target Neighborhood Hits	681	Shared Neighborhood Hits	44
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

NUCKS_HUMAN
θ value	θ > 10 (rank : 125)	NC score	0.072670 (rank : 35)
Query Neighborhood Hits	109	Target Neighborhood Hits	143	Shared Neighborhood Hits	17
SwissProt Accessions	Q9H1E3, Q9H1D6, Q9H723	Gene names	NUCKS1, NUCKS
Domain Architecture	No domain graphic available
Description	Nuclear ubiquitous casein and cyclin-dependent kinases substrate (P1).

NUCKS_MOUSE
θ value	θ > 10 (rank : 126)	NC score	0.078669 (rank : 25)
Query Neighborhood Hits	109	Target Neighborhood Hits	114	Shared Neighborhood Hits	14
SwissProt Accessions	Q80XU3, Q8BVD8	Gene names	Nucks1, Nucks
Domain Architecture	No domain graphic available
Description	Nuclear ubiquitous casein and cyclin-dependent kinases substrate (JC7).

PTMA_HUMAN
θ value	θ > 10 (rank : 127)	NC score	0.098750 (rank : 10)
Query Neighborhood Hits	109	Target Neighborhood Hits	88	Shared Neighborhood Hits	17
SwissProt Accessions	P06454, Q15249, Q15592	Gene names	PTMA, TMSA
Domain Architecture	No domain graphic available
Description	Prothymosin alpha [Contains: Thymosin alpha-1].

PTMA_MOUSE
θ value	θ > 10 (rank : 128)	NC score	0.084713 (rank : 13)
Query Neighborhood Hits	109	Target Neighborhood Hits	73	Shared Neighborhood Hits	12
SwissProt Accessions	P26350, Q3UQV6	Gene names	Ptma
Domain Architecture	No domain graphic available
Description	Prothymosin alpha [Contains: Thymosin alpha].

PTMS_HUMAN
θ value	θ > 10 (rank : 129)	NC score	0.074498 (rank : 32)
Query Neighborhood Hits	109	Target Neighborhood Hits	111	Shared Neighborhood Hits	18
SwissProt Accessions	P20962	Gene names	PTMS
Domain Architecture	No domain graphic available
Description	Parathymosin.

PTMS_MOUSE
θ value	θ > 10 (rank : 130)	NC score	0.073454 (rank : 33)
Query Neighborhood Hits	109	Target Neighborhood Hits	68	Shared Neighborhood Hits	12
SwissProt Accessions	Q9D0J8	Gene names	Ptms
Domain Architecture	No domain graphic available
Description	Parathymosin.

RBM25_HUMAN
θ value	θ > 10 (rank : 131)	NC score	0.057953 (rank : 57)
Query Neighborhood Hits	109	Target Neighborhood Hits	682	Shared Neighborhood Hits	39
SwissProt Accessions	P49756, Q9UEQ5, Q9UIE9	Gene names	RBM25, RNPC7
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 25 (RNA-binding motif protein 25) (RNA- binding region-containing protein 7) (Protein S164).

RENT2_HUMAN
θ value	θ > 10 (rank : 132)	NC score	0.050467 (rank : 78)
Query Neighborhood Hits	109	Target Neighborhood Hits	618	Shared Neighborhood Hits	39
SwissProt Accessions	Q9HAU5, Q8N8U1, Q9H1J2, Q9NWL1, Q9P2D9, Q9Y4M9	Gene names	UPF2, KIAA1408, RENT2
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 2 (Nonsense mRNA reducing factor 2) (Up-frameshift suppressor 2 homolog) (hUpf2).

RPGR1_MOUSE
θ value	θ > 10 (rank : 133)	NC score	0.054646 (rank : 62)
Query Neighborhood Hits	109	Target Neighborhood Hits	713	Shared Neighborhood Hits	48
SwissProt Accessions	Q9EPQ2, Q8CAC2, Q8CDJ9, Q91WE0, Q9CUK6, Q9D5Q1	Gene names	Rpgrip1
Domain Architecture	No domain graphic available
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

SFR11_HUMAN
θ value	θ > 10 (rank : 134)	NC score	0.050034 (rank : 80)
Query Neighborhood Hits	109	Target Neighborhood Hits	246	Shared Neighborhood Hits	16
SwissProt Accessions	Q05519	Gene names	SFRS11
Domain Architecture
Description	Splicing factor arginine/serine-rich 11 (Arginine-rich 54 kDa nuclear protein) (p54).

SFR12_HUMAN
θ value	θ > 10 (rank : 135)	NC score	0.060911 (rank : 53)
Query Neighborhood Hits	109	Target Neighborhood Hits	553	Shared Neighborhood Hits	33
SwissProt Accessions	Q8WXA9, Q86X37	Gene names	SFRS12, SRRP86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86) (Splicing regulatory protein 508) (SRrp508).

SFR12_MOUSE
θ value	θ > 10 (rank : 136)	NC score	0.050997 (rank : 75)
Query Neighborhood Hits	109	Target Neighborhood Hits	486	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BZX4, Q8BLM8, Q8BWK7, Q8BYK0, Q8BYZ4	Gene names	Sfrs12, Srrp86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86).

SRCH_HUMAN
θ value	θ > 10 (rank : 137)	NC score	0.062684 (rank : 49)
Query Neighborhood Hits	109	Target Neighborhood Hits	225	Shared Neighborhood Hits	23
SwissProt Accessions	P23327, Q504Y6	Gene names	HRC, HCP
Domain Architecture	No domain graphic available
Description	Sarcoplasmic reticulum histidine-rich calcium-binding protein precursor.

STX11_HUMAN
θ value	θ > 10 (rank : 138)	NC score	0.054543 (rank : 63)
Query Neighborhood Hits	109	Target Neighborhood Hits	41	Shared Neighborhood Hits	8
SwissProt Accessions	O75558, O75378, O95148	Gene names	STX11
Domain Architecture
Description	Syntaxin-11.

STX11_MOUSE
θ value	θ > 10 (rank : 139)	NC score	0.053871 (rank : 66)
Query Neighborhood Hits	109	Target Neighborhood Hits	76	Shared Neighborhood Hits	9
SwissProt Accessions	Q9D3G5	Gene names	Stx11
Domain Architecture
Description	Syntaxin-11.

STX2_MOUSE
θ value	θ > 10 (rank : 140)	NC score	0.062949 (rank : 47)
Query Neighborhood Hits	109	Target Neighborhood Hits	69	Shared Neighborhood Hits	10
SwissProt Accessions	Q00262	Gene names	Stx2, Epim
Domain Architecture
Description	Syntaxin-2 (Epimorphin).

STX4_HUMAN
θ value	θ > 10 (rank : 141)	NC score	0.062186 (rank : 50)
Query Neighborhood Hits	109	Target Neighborhood Hits	266	Shared Neighborhood Hits	20
SwissProt Accessions	Q12846, Q15525	Gene names	STX4, STX4A
Domain Architecture
Description	Syntaxin-4 (NY-REN-31 antigen).

STX4_MOUSE
θ value	θ > 10 (rank : 142)	NC score	0.054424 (rank : 64)
Query Neighborhood Hits	109	Target Neighborhood Hits	312	Shared Neighborhood Hits	18
SwissProt Accessions	P70452	Gene names	Stx4, Stx4a
Domain Architecture
Description	Syntaxin-4.

T2FA_HUMAN
θ value	θ > 10 (rank : 143)	NC score	0.055662 (rank : 59)
Query Neighborhood Hits	109	Target Neighborhood Hits	228	Shared Neighborhood Hits	22
SwissProt Accessions	P35269, Q9BWN0	Gene names	GTF2F1, RAP74
Domain Architecture
Description	Transcription initiation factor IIF alpha subunit (EC 2.7.11.1) (TFIIF-alpha) (Transcription initiation factor RAP74) (General transcription factor IIF polypeptide 1 74 kDa subunit protein).

ZC313_HUMAN
θ value	θ > 10 (rank : 144)	NC score	0.058573 (rank : 56)
Query Neighborhood Hits	109	Target Neighborhood Hits	772	Shared Neighborhood Hits	42
SwissProt Accessions	Q5T200, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6	Gene names	ZC3H13, KIAA0853
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 13.

Hits sorted by NC score

BMS1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	109	Target Neighborhood Hits	109	Shared Neighborhood Hits	109
SwissProt Accessions	Q14692, Q86XJ9	Gene names	BMS1L, KIAA0187
Domain Architecture
Description	Ribosome biogenesis protein BMS1 homolog.

LEO1_HUMAN
NC score	0.160363 (rank : 2)	θ value	4.1701e-05 (rank : 2)
Query Neighborhood Hits	109	Target Neighborhood Hits	958	Shared Neighborhood Hits	39
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

LEO1_MOUSE
NC score	0.154736 (rank : 3)	θ value	9.29e-05 (rank : 3)
Query Neighborhood Hits	109	Target Neighborhood Hits	946	Shared Neighborhood Hits	40
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

YTDC1_HUMAN
NC score	0.146579 (rank : 4)	θ value	0.00869519 (rank : 4)
Query Neighborhood Hits	109	Target Neighborhood Hits	458	Shared Neighborhood Hits	35
SwissProt Accessions	Q96MU7, Q7Z622, Q8TF35	Gene names	YTHDC1, KIAA1966, YT521
Domain Architecture
Description	YTH domain-containing protein 1 (Putative splicing factor YT521).

DSPP_MOUSE
NC score	0.123743 (rank : 5)	θ value	0.0736092 (rank : 7)
Query Neighborhood Hits	109	Target Neighborhood Hits	491	Shared Neighborhood Hits	26
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

RIOK2_HUMAN
NC score	0.107250 (rank : 6)	θ value	0.0193708 (rank : 5)
Query Neighborhood Hits	109	Target Neighborhood Hits	125	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BVS4, Q9NUT0	Gene names	RIOK2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase RIO2 (EC 2.7.11.1) (RIO kinase 2).

RIF1_HUMAN
NC score	0.106709 (rank : 7)	θ value	0.0736092 (rank : 9)
Query Neighborhood Hits	109	Target Neighborhood Hits	320	Shared Neighborhood Hits	28
SwissProt Accessions	Q5UIP0, Q5H9R3, Q5UIP2, Q66YK6, Q6PRU2, Q8TE94, Q99772, Q9H830, Q9H9B9, Q9NVP5, Q9Y4R4	Gene names	RIF1
Domain Architecture	No domain graphic available
Description	Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog).

SET_HUMAN
NC score	0.102878 (rank : 8)	θ value	0.163984 (rank : 12)
Query Neighborhood Hits	109	Target Neighborhood Hits	71	Shared Neighborhood Hits	15
SwissProt Accessions	Q01105, Q15541, Q5VXV1	Gene names	SET
Domain Architecture
Description	Protein SET (Phosphatase 2A inhibitor I2PP2A) (I-2PP2A) (Template- activating factor I) (TAF-I) (HLA-DR-associated protein II) (PHAPII) (Inhibitor of granzyme A-activated DNase) (IGAAD).

SET_MOUSE
NC score	0.100224 (rank : 9)	θ value	0.163984 (rank : 13)
Query Neighborhood Hits	109	Target Neighborhood Hits	61	Shared Neighborhood Hits	14
SwissProt Accessions	Q9EQU5, Q9CY82, Q9D0A9, Q9Z181	Gene names	Set
Domain Architecture
Description	Protein SET (Phosphatase 2A inhibitor I2PP2A) (I-2PP2A) (Template- activating factor I) (TAF-I).

PTMA_HUMAN
NC score	0.098750 (rank : 10)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	109	Target Neighborhood Hits	88	Shared Neighborhood Hits	17
SwissProt Accessions	P06454, Q15249, Q15592	Gene names	PTMA, TMSA
Domain Architecture	No domain graphic available
Description	Prothymosin alpha [Contains: Thymosin alpha-1].

VPS72_MOUSE
NC score	0.087887 (rank : 11)	θ value	0.62314 (rank : 27)
Query Neighborhood Hits	109	Target Neighborhood Hits	286	Shared Neighborhood Hits	16
SwissProt Accessions	Q62481, Q3U2N4, Q810A9, Q99K81	Gene names	Vps72, Tcfl1, Yl1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

VPS72_HUMAN
NC score	0.087111 (rank : 12)	θ value	0.813845 (rank : 32)
Query Neighborhood Hits	109	Target Neighborhood Hits	274	Shared Neighborhood Hits	16
SwissProt Accessions	Q15906, Q53GJ2, Q5U0R4	Gene names	VPS72, TCFL1, YL1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

PTMA_MOUSE
NC score	0.084713 (rank : 13)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	109	Target Neighborhood Hits	73	Shared Neighborhood Hits	12
SwissProt Accessions	P26350, Q3UQV6	Gene names	Ptma
Domain Architecture	No domain graphic available
Description	Prothymosin alpha [Contains: Thymosin alpha].

ERIC1_HUMAN
NC score	0.084173 (rank : 14)	θ value	1.81305 (rank : 40)
Query Neighborhood Hits	109	Target Neighborhood Hits	364	Shared Neighborhood Hits	18
SwissProt Accessions	Q86X53, Q9P063	Gene names	ERICH1
Domain Architecture	No domain graphic available
Description	Glutamate-rich protein 1.

STX1C_HUMAN
NC score	0.083953 (rank : 15)	θ value	0.62314 (rank : 25)
Query Neighborhood Hits	109	Target Neighborhood Hits	270	Shared Neighborhood Hits	21
SwissProt Accessions	P61266	Gene names	STX1B2
Domain Architecture
Description	Syntaxin-1B2.

STX1C_MOUSE
NC score	0.083953 (rank : 16)	θ value	0.62314 (rank : 26)
Query Neighborhood Hits	109	Target Neighborhood Hits	270	Shared Neighborhood Hits	21
SwissProt Accessions	P61264, P32853	Gene names	Stx1b2, Stx1b
Domain Architecture
Description	Syntaxin-1B2 (Syntaxin 1B).

NSBP1_HUMAN
NC score	0.083878 (rank : 17)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	109	Target Neighborhood Hits	251	Shared Neighborhood Hits	29
SwissProt Accessions	P82970	Gene names	NSBP1
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1.

HTSF1_MOUSE
NC score	0.083781 (rank : 18)	θ value	8.99809 (rank : 98)
Query Neighborhood Hits	109	Target Neighborhood Hits	425	Shared Neighborhood Hits	37
SwissProt Accessions	Q8BGC0, Q1WWK0, Q9CT41, Q9DAU3	Gene names	Htatsf1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 homolog.

RIF1_MOUSE
NC score	0.083021 (rank : 19)	θ value	1.81305 (rank : 42)
Query Neighborhood Hits	109	Target Neighborhood Hits	315	Shared Neighborhood Hits	18
SwissProt Accessions	Q6PR54, Q6T8D9, Q7TPD8, Q8BTU2, Q8C408, Q9CS77	Gene names	Rif1
Domain Architecture	No domain graphic available
Description	Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog) (mRif1).

DSPP_HUMAN
NC score	0.082877 (rank : 20)	θ value	θ > 10 (rank : 117)
Query Neighborhood Hits	109	Target Neighborhood Hits	645	Shared Neighborhood Hits	31
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

STX1B_HUMAN
NC score	0.079701 (rank : 21)	θ value	1.81305 (rank : 46)
Query Neighborhood Hits	109	Target Neighborhood Hits	252	Shared Neighborhood Hits	19
SwissProt Accessions	Q15531	Gene names	STX1B1, STX1B
Domain Architecture
Description	Syntaxin-1B1 (Syntaxin 1B).

STX1A_MOUSE
NC score	0.079581 (rank : 22)	θ value	2.36792 (rank : 55)
Query Neighborhood Hits	109	Target Neighborhood Hits	261	Shared Neighborhood Hits	21
SwissProt Accessions	O35526	Gene names	Stx1a
Domain Architecture
Description	Syntaxin-1A (Neuron-specific antigen HPC-1).

STX3_MOUSE
NC score	0.079472 (rank : 23)	θ value	2.36792 (rank : 57)
Query Neighborhood Hits	109	Target Neighborhood Hits	212	Shared Neighborhood Hits	19
SwissProt Accessions	Q64704	Gene names	Stx3, Stx3a
Domain Architecture
Description	Syntaxin-3.

STX1A_HUMAN
NC score	0.079392 (rank : 24)	θ value	2.36792 (rank : 54)
Query Neighborhood Hits	109	Target Neighborhood Hits	266	Shared Neighborhood Hits	21
SwissProt Accessions	Q16623, O15447, O15448, Q12936, Q9BPZ6	Gene names	STX1A, STX1
Domain Architecture
Description	Syntaxin-1A (Neuron-specific antigen HPC-1).

NUCKS_MOUSE
NC score	0.078669 (rank : 25)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	109	Target Neighborhood Hits	114	Shared Neighborhood Hits	14
SwissProt Accessions	Q80XU3, Q8BVD8	Gene names	Nucks1, Nucks
Domain Architecture	No domain graphic available
Description	Nuclear ubiquitous casein and cyclin-dependent kinases substrate (JC7).

STX3_HUMAN
NC score	0.078355 (rank : 26)	θ value	2.36792 (rank : 56)
Query Neighborhood Hits	109	Target Neighborhood Hits	211	Shared Neighborhood Hits	19
SwissProt Accessions	Q13277, O43750, O43751, Q15360	Gene names	STX3, STX3A
Domain Architecture
Description	Syntaxin-3.

DMP1_MOUSE
NC score	0.077734 (rank : 27)	θ value	θ > 10 (rank : 116)
Query Neighborhood Hits	109	Target Neighborhood Hits	498	Shared Neighborhood Hits	33
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

IWS1_HUMAN
NC score	0.077194 (rank : 28)	θ value	3.0926 (rank : 62)
Query Neighborhood Hits	109	Target Neighborhood Hits	1241	Shared Neighborhood Hits	56
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

REPS1_HUMAN
NC score	0.075683 (rank : 29)	θ value	1.38821 (rank : 38)
Query Neighborhood Hits	109	Target Neighborhood Hits	205	Shared Neighborhood Hits	15
SwissProt Accessions	Q96D71, Q8NDR7, Q8WU62, Q9BXY9	Gene names	REPS1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1).

RPGR_MOUSE
NC score	0.075564 (rank : 30)	θ value	0.0431538 (rank : 6)
Query Neighborhood Hits	109	Target Neighborhood Hits	281	Shared Neighborhood Hits	22
SwissProt Accessions	Q9R0X5, O88408, Q9CU92	Gene names	Rpgr
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator (mRpgr).

IWS1_MOUSE
NC score	0.075047 (rank : 31)	θ value	4.03905 (rank : 69)
Query Neighborhood Hits	109	Target Neighborhood Hits	1258	Shared Neighborhood Hits	50
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

PTMS_HUMAN
NC score	0.074498 (rank : 32)	θ value	θ > 10 (rank : 129)
Query Neighborhood Hits	109	Target Neighborhood Hits	111	Shared Neighborhood Hits	18
SwissProt Accessions	P20962	Gene names	PTMS
Domain Architecture	No domain graphic available
Description	Parathymosin.

PTMS_MOUSE
NC score	0.073454 (rank : 33)	θ value	θ > 10 (rank : 130)
Query Neighborhood Hits	109	Target Neighborhood Hits	68	Shared Neighborhood Hits	12
SwissProt Accessions	Q9D0J8	Gene names	Ptms
Domain Architecture	No domain graphic available
Description	Parathymosin.

REPS1_MOUSE
NC score	0.072980 (rank : 34)	θ value	1.81305 (rank : 41)
Query Neighborhood Hits	109	Target Neighborhood Hits	204	Shared Neighborhood Hits	13
SwissProt Accessions	O54916, Q8C9J9, Q99LR8	Gene names	Reps1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1).

NUCKS_HUMAN
NC score	0.072670 (rank : 35)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	109	Target Neighborhood Hits	143	Shared Neighborhood Hits	17
SwissProt Accessions	Q9H1E3, Q9H1D6, Q9H723	Gene names	NUCKS1, NUCKS
Domain Architecture	No domain graphic available
Description	Nuclear ubiquitous casein and cyclin-dependent kinases substrate (P1).

DMP1_HUMAN
NC score	0.072293 (rank : 36)	θ value	θ > 10 (rank : 115)
Query Neighborhood Hits	109	Target Neighborhood Hits	491	Shared Neighborhood Hits	37
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

STX2_HUMAN
NC score	0.071516 (rank : 37)	θ value	8.99809 (rank : 106)
Query Neighborhood Hits	109	Target Neighborhood Hits	158	Shared Neighborhood Hits	15
SwissProt Accessions	P32856, Q86VW8	Gene names	STX2, EPIM
Domain Architecture
Description	Syntaxin-2 (Epimorphin).

ATRX_MOUSE
NC score	0.069912 (rank : 38)	θ value	0.62314 (rank : 21)
Query Neighborhood Hits	109	Target Neighborhood Hits	682	Shared Neighborhood Hits	43
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

CYLC2_HUMAN
NC score	0.068286 (rank : 39)	θ value	θ > 10 (rank : 114)
Query Neighborhood Hits	109	Target Neighborhood Hits	223	Shared Neighborhood Hits	23
SwissProt Accessions	Q14093	Gene names	CYLC2, CYL2
Domain Architecture	No domain graphic available
Description	Cylicin-2 (Cylicin II) (Multiple-band polypeptide II).

TCAL5_HUMAN
NC score	0.067556 (rank : 40)	θ value	0.21417 (rank : 15)
Query Neighborhood Hits	109	Target Neighborhood Hits	806	Shared Neighborhood Hits	29
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

IPP2_MOUSE
NC score	0.067310 (rank : 41)	θ value	1.06291 (rank : 33)
Query Neighborhood Hits	109	Target Neighborhood Hits	49	Shared Neighborhood Hits	4
SwissProt Accessions	Q9DCL8, Q3UD25, Q8C1A6	Gene names	Ppp1r2
Domain Architecture	No domain graphic available
Description	Protein phosphatase inhibitor 2 (IPP-2).

IF2P_HUMAN
NC score	0.066864 (rank : 42)	θ value	θ > 10 (rank : 120)
Query Neighborhood Hits	109	Target Neighborhood Hits	889	Shared Neighborhood Hits	56
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

EP15R_HUMAN
NC score	0.066258 (rank : 43)	θ value	0.279714 (rank : 17)
Query Neighborhood Hits	109	Target Neighborhood Hits	1083	Shared Neighborhood Hits	41
SwissProt Accessions	Q9UBC2	Gene names	EPS15L1, EPS15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R).

NSBP1_MOUSE
NC score	0.065894 (rank : 44)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	109	Target Neighborhood Hits	681	Shared Neighborhood Hits	44
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

HTSF1_HUMAN
NC score	0.064941 (rank : 45)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	109	Target Neighborhood Hits	408	Shared Neighborhood Hits	35
SwissProt Accessions	O43719, Q59G06, Q99730	Gene names	HTATSF1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 (Tat-SF1).

EP15R_MOUSE
NC score	0.064693 (rank : 46)	θ value	0.365318 (rank : 18)
Query Neighborhood Hits	109	Target Neighborhood Hits	1135	Shared Neighborhood Hits	35
SwissProt Accessions	Q60902, Q8CB60, Q8CB70, Q91WH8	Gene names	Eps15l1, Eps15-rs, Eps15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs).

STX2_MOUSE
NC score	0.062949 (rank : 47)	θ value	θ > 10 (rank : 140)
Query Neighborhood Hits	109	Target Neighborhood Hits	69	Shared Neighborhood Hits	10
SwissProt Accessions	Q00262	Gene names	Stx2, Epim
Domain Architecture
Description	Syntaxin-2 (Epimorphin).

CT151_HUMAN
NC score	0.062746 (rank : 48)	θ value	1.38821 (rank : 36)
Query Neighborhood Hits	109	Target Neighborhood Hits	382	Shared Neighborhood Hits	16
SwissProt Accessions	Q8NC74, Q8N4Z9, Q9BR75, Q9H0Y9	Gene names	C20orf151
Domain Architecture
Description	Uncharacterized protein C20orf151.

SRCH_HUMAN
NC score	0.062684 (rank : 49)	θ value	θ > 10 (rank : 137)
Query Neighborhood Hits	109	Target Neighborhood Hits	225	Shared Neighborhood Hits	23
SwissProt Accessions	P23327, Q504Y6	Gene names	HRC, HCP
Domain Architecture	No domain graphic available
Description	Sarcoplasmic reticulum histidine-rich calcium-binding protein precursor.

STX4_HUMAN
NC score	0.062186 (rank : 50)	θ value	θ > 10 (rank : 141)
Query Neighborhood Hits	109	Target Neighborhood Hits	266	Shared Neighborhood Hits	20
SwissProt Accessions	Q12846, Q15525	Gene names	STX4, STX4A
Domain Architecture
Description	Syntaxin-4 (NY-REN-31 antigen).

CYLC1_HUMAN
NC score	0.061881 (rank : 51)	θ value	θ > 10 (rank : 113)
Query Neighborhood Hits	109	Target Neighborhood Hits	408	Shared Neighborhood Hits	30
SwissProt Accessions	P35663, Q5JQQ9	Gene names	CYLC1, CYL, CYL1
Domain Architecture	No domain graphic available
Description	Cylicin-1 (Cylicin I) (Multiple-band polypeptide I).

CCD55_MOUSE
NC score	0.061405 (rank : 52)	θ value	6.88961 (rank : 85)
Query Neighborhood Hits	109	Target Neighborhood Hits	519	Shared Neighborhood Hits	33
SwissProt Accessions	Q5NCR9	Gene names	Ccdc55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

SFR12_HUMAN
NC score	0.060911 (rank : 53)	θ value	θ > 10 (rank : 135)
Query Neighborhood Hits	109	Target Neighborhood Hits	553	Shared Neighborhood Hits	33
SwissProt Accessions	Q8WXA9, Q86X37	Gene names	SFRS12, SRRP86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86) (Splicing regulatory protein 508) (SRrp508).

ATRX_HUMAN
NC score	0.060668 (rank : 54)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	109	Target Neighborhood Hits	842	Shared Neighborhood Hits	46
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

CCD93_HUMAN
NC score	0.059192 (rank : 55)	θ value	0.163984 (rank : 10)
Query Neighborhood Hits	109	Target Neighborhood Hits	600	Shared Neighborhood Hits	22
SwissProt Accessions	Q567U6, Q4LE78, Q53TJ2, Q8TBX5, Q9H6R5, Q9NV15	Gene names	CCDC93
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 93.

ZC313_HUMAN
NC score	0.058573 (rank : 56)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	109	Target Neighborhood Hits	772	Shared Neighborhood Hits	42
SwissProt Accessions	Q5T200, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6	Gene names	ZC3H13, KIAA0853
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 13.

RBM25_HUMAN
NC score	0.057953 (rank : 57)	θ value	θ > 10 (rank : 131)
Query Neighborhood Hits	109	Target Neighborhood Hits	682	Shared Neighborhood Hits	39
SwissProt Accessions	P49756, Q9UEQ5, Q9UIE9	Gene names	RBM25, RNPC7
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 25 (RNA-binding motif protein 25) (RNA- binding region-containing protein 7) (Protein S164).

CALD1_HUMAN
NC score	0.057865 (rank : 58)	θ value	θ > 10 (rank : 111)
Query Neighborhood Hits	109	Target Neighborhood Hits	959	Shared Neighborhood Hits	50
SwissProt Accessions	Q05682, Q13978, Q13979, Q14741, Q14742	Gene names	CALD1, CAD, CDM
Domain Architecture
Description	Caldesmon (CDM).

T2FA_HUMAN
NC score	0.055662 (rank : 59)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	109	Target Neighborhood Hits	228	Shared Neighborhood Hits	22
SwissProt Accessions	P35269, Q9BWN0	Gene names	GTF2F1, RAP74
Domain Architecture
Description	Transcription initiation factor IIF alpha subunit (EC 2.7.11.1) (TFIIF-alpha) (Transcription initiation factor RAP74) (General transcription factor IIF polypeptide 1 74 kDa subunit protein).

MFAP1_MOUSE
NC score	0.055248 (rank : 60)	θ value	θ > 10 (rank : 122)
Query Neighborhood Hits	109	Target Neighborhood Hits	353	Shared Neighborhood Hits	36
SwissProt Accessions	Q9CQU1, Q3TU29, Q8CCL1, Q9CSJ5	Gene names	Mfap1
Domain Architecture	No domain graphic available
Description	Microfibrillar-associated protein 1.

TP53B_MOUSE
NC score	0.054746 (rank : 61)	θ value	1.81305 (rank : 48)
Query Neighborhood Hits	109	Target Neighborhood Hits	644	Shared Neighborhood Hits	24
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

RPGR1_MOUSE
NC score	0.054646 (rank : 62)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	109	Target Neighborhood Hits	713	Shared Neighborhood Hits	48
SwissProt Accessions	Q9EPQ2, Q8CAC2, Q8CDJ9, Q91WE0, Q9CUK6, Q9D5Q1	Gene names	Rpgrip1
Domain Architecture	No domain graphic available
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

STX11_HUMAN
NC score	0.054543 (rank : 63)	θ value	θ > 10 (rank : 138)
Query Neighborhood Hits	109	Target Neighborhood Hits	41	Shared Neighborhood Hits	8
SwissProt Accessions	O75558, O75378, O95148	Gene names	STX11
Domain Architecture
Description	Syntaxin-11.

STX4_MOUSE
NC score	0.054424 (rank : 64)	θ value	θ > 10 (rank : 142)
Query Neighborhood Hits	109	Target Neighborhood Hits	312	Shared Neighborhood Hits	18
SwissProt Accessions	P70452	Gene names	Stx4, Stx4a
Domain Architecture
Description	Syntaxin-4.

HIRP3_HUMAN
NC score	0.054193 (rank : 65)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	109	Target Neighborhood Hits	323	Shared Neighborhood Hits	32
SwissProt Accessions	Q9BW71, O75707, O75708	Gene names	HIRIP3
Domain Architecture	No domain graphic available
Description	HIRA-interacting protein 3.

STX11_MOUSE
NC score	0.053871 (rank : 66)	θ value	θ > 10 (rank : 139)
Query Neighborhood Hits	109	Target Neighborhood Hits	76	Shared Neighborhood Hits	9
SwissProt Accessions	Q9D3G5	Gene names	Stx11
Domain Architecture
Description	Syntaxin-11.

SMC1A_HUMAN
NC score	0.053834 (rank : 67)	θ value	0.62314 (rank : 23)
Query Neighborhood Hits	109	Target Neighborhood Hits	1346	Shared Neighborhood Hits	47
SwissProt Accessions	Q14683, O14995, Q16351	Gene names	SMC1L1, DXS423E, KIAA0178, SB1.8, SMC1
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Sb1.8).

BPTF_HUMAN
NC score	0.053614 (rank : 68)	θ value	2.36792 (rank : 50)
Query Neighborhood Hits	109	Target Neighborhood Hits	786	Shared Neighborhood Hits	41
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

FA21C_HUMAN
NC score	0.052903 (rank : 69)	θ value	8.99809 (rank : 96)
Query Neighborhood Hits	109	Target Neighborhood Hits	194	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y4E1, Q5SQU4, Q5SQU5, Q7L521, Q9UG79	Gene names	FAM21C, KIAA0592
Domain Architecture	No domain graphic available
Description	Protein FAM21C.

BAZ1B_HUMAN
NC score	0.052536 (rank : 70)	θ value	0.279714 (rank : 16)
Query Neighborhood Hits	109	Target Neighborhood Hits	701	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

SMC1A_MOUSE
NC score	0.052346 (rank : 71)	θ value	0.62314 (rank : 24)
Query Neighborhood Hits	109	Target Neighborhood Hits	1384	Shared Neighborhood Hits	47
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

MDN1_HUMAN
NC score	0.051929 (rank : 72)	θ value	θ > 10 (rank : 121)
Query Neighborhood Hits	109	Target Neighborhood Hits	662	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

SEC63_HUMAN
NC score	0.051359 (rank : 73)	θ value	2.36792 (rank : 53)
Query Neighborhood Hits	109	Target Neighborhood Hits	586	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UGP8, O95380, Q86VS9, Q8IWL0, Q9NTE0	Gene names	SEC63, SEC63L
Domain Architecture
Description	Translocation protein SEC63 homolog.

ITSN1_HUMAN
NC score	0.051136 (rank : 74)	θ value	0.0736092 (rank : 8)
Query Neighborhood Hits	109	Target Neighborhood Hits	1757	Shared Neighborhood Hits	43
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

SFR12_MOUSE
NC score	0.050997 (rank : 75)	θ value	θ > 10 (rank : 136)
Query Neighborhood Hits	109	Target Neighborhood Hits	486	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BZX4, Q8BLM8, Q8BWK7, Q8BYK0, Q8BYZ4	Gene names	Sfrs12, Srrp86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86).

WBP11_MOUSE
NC score	0.050855 (rank : 76)	θ value	8.99809 (rank : 109)
Query Neighborhood Hits	109	Target Neighborhood Hits	362	Shared Neighborhood Hits	21
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

CCAR1_HUMAN
NC score	0.050510 (rank : 77)	θ value	θ > 10 (rank : 112)
Query Neighborhood Hits	109	Target Neighborhood Hits	444	Shared Neighborhood Hits	41
SwissProt Accessions	Q8IX12, Q32NE3, Q5VUP6, Q6PIZ0, Q6X935, Q9H8N4, Q9NVA7, Q9NVQ0, Q9NWM6	Gene names	CCAR1, CARP1, DIS
Domain Architecture	No domain graphic available
Description	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1) (Death inducer with SAP domain).

RENT2_HUMAN
NC score	0.050467 (rank : 78)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	109	Target Neighborhood Hits	618	Shared Neighborhood Hits	39
SwissProt Accessions	Q9HAU5, Q8N8U1, Q9H1J2, Q9NWL1, Q9P2D9, Q9Y4M9	Gene names	UPF2, KIAA1408, RENT2
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 2 (Nonsense mRNA reducing factor 2) (Up-frameshift suppressor 2 homolog) (hUpf2).

NC6IP_MOUSE
NC score	0.050093 (rank : 79)	θ value	4.03905 (rank : 71)
Query Neighborhood Hits	109	Target Neighborhood Hits	161	Shared Neighborhood Hits	11
SwissProt Accessions	Q923W1, Q6DI60, Q6PEA7, Q8R0W9	Gene names	Ncoa6ip, Pimt
Domain Architecture	No domain graphic available
Description	Putative RNA methyltransferase NCOA6IP (EC 2.1.1.-) (Nuclear receptor coactivator 6-interacting protein) (PRIP-interacting protein with methyltransferase motif) (PIPMT) (PIMT).

SFR11_HUMAN
NC score	0.050034 (rank : 80)	θ value	θ > 10 (rank : 134)
Query Neighborhood Hits	109	Target Neighborhood Hits	246	Shared Neighborhood Hits	16
SwissProt Accessions	Q05519	Gene names	SFRS11
Domain Architecture
Description	Splicing factor arginine/serine-rich 11 (Arginine-rich 54 kDa nuclear protein) (p54).

SELB_HUMAN
NC score	0.048889 (rank : 81)	θ value	1.81305 (rank : 44)
Query Neighborhood Hits	109	Target Neighborhood Hits	37	Shared Neighborhood Hits	3
SwissProt Accessions	P57772	Gene names	EEFSEC, SELB
Domain Architecture
Description	Selenocysteine-specific elongation factor (Elongation factor sec) (Eukaryotic elongation factor, selenocysteine-tRNA-specific).

WBP11_HUMAN
NC score	0.048327 (rank : 82)	θ value	8.99809 (rank : 108)
Query Neighborhood Hits	109	Target Neighborhood Hits	354	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

GOGB1_HUMAN
NC score	0.047713 (rank : 83)	θ value	0.21417 (rank : 14)
Query Neighborhood Hits	109	Target Neighborhood Hits	2297	Shared Neighborhood Hits	64
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

SELB_MOUSE
NC score	0.047700 (rank : 84)	θ value	1.81305 (rank : 45)
Query Neighborhood Hits	109	Target Neighborhood Hits	38	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JHW4	Gene names	Eefsec, Selb
Domain Architecture
Description	Selenocysteine-specific elongation factor (Elongation factor sec) (Eukaryotic elongation factor, selenocysteine-tRNA-specific) (mSelB).

SPRL1_MOUSE
NC score	0.047538 (rank : 85)	θ value	8.99809 (rank : 104)
Query Neighborhood Hits	109	Target Neighborhood Hits	403	Shared Neighborhood Hits	24
SwissProt Accessions	P70663, P97810, Q99L82	Gene names	Sparcl1, Ecm2, Sc1
Domain Architecture
Description	SPARC-like protein 1 precursor (Matrix glycoprotein Sc1) (Extracellular matrix protein 2).

MYST4_HUMAN
NC score	0.045691 (rank : 86)	θ value	8.99809 (rank : 100)
Query Neighborhood Hits	109	Target Neighborhood Hits	671	Shared Neighborhood Hits	42
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

NCOA7_HUMAN
NC score	0.045586 (rank : 87)	θ value	0.813845 (rank : 30)
Query Neighborhood Hits	109	Target Neighborhood Hits	160	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NI08, Q3LID6, Q4G0V1, Q5TF95, Q6IPQ4, Q6NE83, Q86T89, Q8N1W4	Gene names	NCOA7, ERAP140, ESNA1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 7 (140 kDa estrogen receptor-associated protein) (Estrogen nuclear receptor coactivator 1).

SEMG2_HUMAN
NC score	0.045273 (rank : 88)	θ value	6.88961 (rank : 92)
Query Neighborhood Hits	109	Target Neighborhood Hits	251	Shared Neighborhood Hits	17
SwissProt Accessions	Q02383, Q6X2M6	Gene names	SEMG2
Domain Architecture
Description	Semenogelin-2 precursor (Semenogelin II) (SGII).

BRD8_MOUSE
NC score	0.044956 (rank : 89)	θ value	3.0926 (rank : 59)
Query Neighborhood Hits	109	Target Neighborhood Hits	422	Shared Neighborhood Hits	21
SwissProt Accessions	Q8R3B7, Q8C049, Q8R583, Q8VDP0	Gene names	Brd8
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8.

ITSN1_MOUSE
NC score	0.044042 (rank : 90)	θ value	6.88961 (rank : 88)
Query Neighborhood Hits	109	Target Neighborhood Hits	1669	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

SDCG1_MOUSE
NC score	0.043990 (rank : 91)	θ value	3.0926 (rank : 64)
Query Neighborhood Hits	109	Target Neighborhood Hits	168	Shared Neighborhood Hits	13
SwissProt Accessions	Q8CCP0, Q66JX6, Q8C9R6, Q8CA65, Q8JZT9, Q8R072, Q9CW30, Q9CYB8, Q9D4A9	Gene names	Sdccag1
Domain Architecture
Description	Serologically defined colon cancer antigen 1.

GLE1_MOUSE
NC score	0.043964 (rank : 92)	θ value	3.0926 (rank : 61)
Query Neighborhood Hits	109	Target Neighborhood Hits	504	Shared Neighborhood Hits	21
SwissProt Accessions	Q8R322, Q3TT10, Q3TU23, Q3UD65, Q8BT16, Q9D4A6	Gene names	Gle1l
Domain Architecture	No domain graphic available
Description	Nucleoporin GLE1 (GLE1-like protein).

FANCJ_MOUSE
NC score	0.042329 (rank : 93)	θ value	0.813845 (rank : 28)
Query Neighborhood Hits	109	Target Neighborhood Hits	57	Shared Neighborhood Hits	2
SwissProt Accessions	Q5SXJ3, Q8BJQ8, Q8BKI6	Gene names	Brip1, Bach1, Fancj
Domain Architecture	No domain graphic available
Description	Fanconi anemia group J protein homolog (EC 3.6.1.-) (ATP-dependent RNA helicase BRIP1) (Protein FACJ) (BRCA1-interacting protein C-terminal helicase 1) (BRCA1-interacting protein 1) (BRCA1-associated C-terminal helicase 1).

MLL3_HUMAN
NC score	0.041980 (rank : 94)	θ value	0.365318 (rank : 19)
Query Neighborhood Hits	109	Target Neighborhood Hits	1644	Shared Neighborhood Hits	32
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

OPTN_HUMAN
NC score	0.041913 (rank : 95)	θ value	3.0926 (rank : 63)
Query Neighborhood Hits	109	Target Neighborhood Hits	827	Shared Neighborhood Hits	32
SwissProt Accessions	Q96CV9, Q5T672, Q5T673, Q5T674, Q5T675, Q7LDL9, Q8N562, Q9UET9, Q9UEV4, Q9Y218	Gene names	OPTN, FIP2, GLC1E, NRP
Domain Architecture	No domain graphic available
Description	Optineurin (Optic neuropathy-inducing protein) (E3-14.7K-interacting protein) (FIP-2) (Huntingtin-interacting protein HYPL) (NEMO-related protein) (Transcription factor IIIA-interacting protein) (TFIIIA- IntP).

WDR67_HUMAN
NC score	0.040948 (rank : 96)	θ value	1.38821 (rank : 39)
Query Neighborhood Hits	109	Target Neighborhood Hits	782	Shared Neighborhood Hits	17
SwissProt Accessions	Q96DN5, Q3MIR6, Q8TBP9	Gene names	WDR67
Domain Architecture	No domain graphic available
Description	WD repeat protein 67.

SEL1L_MOUSE
NC score	0.040882 (rank : 97)	θ value	1.06291 (rank : 34)
Query Neighborhood Hits	109	Target Neighborhood Hits	62	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z2G6, Q9DBD8	Gene names	Sel1l, Sel1h
Domain Architecture
Description	Sel-1 homolog precursor (Suppressor of lin-12-like protein) (Sel-1L).

OSBL8_HUMAN
NC score	0.040723 (rank : 98)	θ value	1.38821 (rank : 37)
Query Neighborhood Hits	109	Target Neighborhood Hits	289	Shared Neighborhood Hits	23
SwissProt Accessions	Q9BZF1, Q8WXP8, Q9P277	Gene names	OSBPL8, KIAA1451, ORP8, OSBP10
Domain Architecture
Description	Oxysterol-binding protein-related protein 8 (OSBP-related protein 8) (ORP-8).

TOIP1_HUMAN
NC score	0.040399 (rank : 99)	θ value	2.36792 (rank : 58)
Query Neighborhood Hits	109	Target Neighborhood Hits	58	Shared Neighborhood Hits	7
SwissProt Accessions	Q5JTV8, Q5JTV6, Q8IZ65, Q9H8Y6, Q9HAJ1, Q9NV52, Q9Y3X5	Gene names	TOR1AIP1
Domain Architecture	No domain graphic available
Description	Torsin-1A-interacting protein 1.

TTC1_HUMAN
NC score	0.039397 (rank : 100)	θ value	1.81305 (rank : 49)
Query Neighborhood Hits	109	Target Neighborhood Hits	417	Shared Neighborhood Hits	17
SwissProt Accessions	Q99614, Q9BVT3	Gene names	TTC1, TPR1
Domain Architecture
Description	Tetratricopeptide repeat protein 1 (TPR repeat protein 1).

CASC5_HUMAN
NC score	0.039363 (rank : 101)	θ value	5.27518 (rank : 73)
Query Neighborhood Hits	109	Target Neighborhood Hits	376	Shared Neighborhood Hits	20
SwissProt Accessions	Q8NG31, Q8NHE1, Q8WXA6, Q9HCK2, Q9NR92	Gene names	CASC5, KIAA1570
Domain Architecture	No domain graphic available
Description	Protein CASC5 (Cancer susceptibility candidate gene 5 protein) (ALL1- fused gene from chromosome 15q14) (AF15q14) (D40/AF15q14 protein).

CC47_MOUSE
NC score	0.038854 (rank : 102)	θ value	8.99809 (rank : 93)
Query Neighborhood Hits	109	Target Neighborhood Hits	245	Shared Neighborhood Hits	18
SwissProt Accessions	Q9D024, Q3TSB5, Q3V1S7, Q8C5D9, Q920S6	Gene names	Ccdc47, Asp4
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 47 precursor (Adipocyte-specific protein 4).

RAI14_MOUSE
NC score	0.037569 (rank : 103)	θ value	0.163984 (rank : 11)
Query Neighborhood Hits	109	Target Neighborhood Hits	1505	Shared Neighborhood Hits	42
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

CJ068_HUMAN
NC score	0.036670 (rank : 104)	θ value	8.99809 (rank : 94)
Query Neighborhood Hits	109	Target Neighborhood Hits	316	Shared Neighborhood Hits	21
SwissProt Accessions	Q9H943, Q8N7T7	Gene names	C10orf68
Domain Architecture	No domain graphic available
Description	Protein C10orf68.

SASH1_HUMAN
NC score	0.035336 (rank : 105)	θ value	1.81305 (rank : 43)
Query Neighborhood Hits	109	Target Neighborhood Hits	292	Shared Neighborhood Hits	9
SwissProt Accessions	O94885, Q8TAI0, Q9H7R7	Gene names	SASH1, KIAA0790, PEPE1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1 (Proline-glutamate repeat- containing protein).

CT2NL_HUMAN
NC score	0.034866 (rank : 106)	θ value	6.88961 (rank : 86)
Query Neighborhood Hits	109	Target Neighborhood Hits	1059	Shared Neighborhood Hits	32
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

SPAG1_MOUSE
NC score	0.034603 (rank : 107)	θ value	1.06291 (rank : 35)
Query Neighborhood Hits	109	Target Neighborhood Hits	218	Shared Neighborhood Hits	7
SwissProt Accessions	Q80ZX8, Q8CCK7, Q9QZJ3, Q9QZJ4	Gene names	Spag1, Tpis
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 1 (Infertility-related sperm protein Spag-1) (TPR-containing protein involved in spermatogenesis) (TPIS).

SYNE2_HUMAN
NC score	0.034391 (rank : 108)	θ value	1.81305 (rank : 47)
Query Neighborhood Hits	109	Target Neighborhood Hits	1323	Shared Neighborhood Hits	38
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

CT2NL_MOUSE
NC score	0.034109 (rank : 109)	θ value	8.99809 (rank : 95)
Query Neighborhood Hits	109	Target Neighborhood Hits	902	Shared Neighborhood Hits	25
SwissProt Accessions	Q99LJ0, Q6ZPR0, Q8BSV1	Gene names	Cttnbp2nl, Kiaa1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

CING_MOUSE
NC score	0.033955 (rank : 110)	θ value	5.27518 (rank : 75)
Query Neighborhood Hits	109	Target Neighborhood Hits	1432	Shared Neighborhood Hits	40
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

GOGA4_MOUSE
NC score	0.033622 (rank : 111)	θ value	8.99809 (rank : 97)
Query Neighborhood Hits	109	Target Neighborhood Hits	1939	Shared Neighborhood Hits	52
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

BTAF1_HUMAN
NC score	0.033447 (rank : 112)	θ value	0.47712 (rank : 20)
Query Neighborhood Hits	109	Target Neighborhood Hits	97	Shared Neighborhood Hits	4
SwissProt Accessions	O14981, O43578	Gene names	BTAF1, TAF172
Domain Architecture
Description	TATA-binding protein-associated factor 172 (EC 3.6.1.-) (ATP-dependent helicase BTAF1) (TBP-associated factor 172) (TAF-172) (TAF(II)170) (B- TFIID transcription factor-associated 170 kDa subunit).

CL026_HUMAN
NC score	0.032156 (rank : 113)	θ value	4.03905 (rank : 68)
Query Neighborhood Hits	109	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N6Q8, Q9H5Y3	Gene names	C12orf26
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C12orf26.

UBP42_HUMAN
NC score	0.031065 (rank : 114)	θ value	0.813845 (rank : 31)
Query Neighborhood Hits	109	Target Neighborhood Hits	445	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

CIA30_MOUSE
NC score	0.030714 (rank : 115)	θ value	5.27518 (rank : 74)
Query Neighborhood Hits	109	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CWX2, Q8VEI8	Gene names	Ndufaf1, Cia30
Domain Architecture	No domain graphic available
Description	Complex I intermediate-associated protein 30, mitochondrial precursor (NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 1).

REST_MOUSE
NC score	0.030663 (rank : 116)	θ value	6.88961 (rank : 90)
Query Neighborhood Hits	109	Target Neighborhood Hits	1506	Shared Neighborhood Hits	41
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

UB7I1_MOUSE
NC score	0.028424 (rank : 117)	θ value	3.0926 (rank : 66)
Query Neighborhood Hits	109	Target Neighborhood Hits	206	Shared Neighborhood Hits	4
SwissProt Accessions	P58283, Q3U493, Q3UE56, Q3UGM3, Q68FN0, Q6P1H8, Q6PWY5, Q8BN27, Q8C1U3	Gene names	Ubce7ip1, Triad3, Uip83, Zin
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase TRIAD3 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (UbcM4-interacting protein 83) (Triad domain- containing protein 3).

NAL14_HUMAN
NC score	0.027917 (rank : 118)	θ value	0.813845 (rank : 29)
Query Neighborhood Hits	109	Target Neighborhood Hits	76	Shared Neighborhood Hits	3
SwissProt Accessions	Q86W24, Q7RTR6	Gene names	NALP14, NOD5
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 14 (Nucleotide-binding oligomerization domain protein 5).

K0423_MOUSE
NC score	0.027839 (rank : 119)	θ value	5.27518 (rank : 78)
Query Neighborhood Hits	109	Target Neighborhood Hits	115	Shared Neighborhood Hits	7
SwissProt Accessions	Q6A070	Gene names	Kiaa0423
Domain Architecture	No domain graphic available
Description	Protein KIAA0423.

WRN_MOUSE
NC score	0.025312 (rank : 120)	θ value	4.03905 (rank : 72)
Query Neighborhood Hits	109	Target Neighborhood Hits	295	Shared Neighborhood Hits	18
SwissProt Accessions	O09053, O09050, Q9JKD4, Q9Z241, Q9Z242	Gene names	Wrn
Domain Architecture
Description	Werner syndrome ATP-dependent helicase homolog (EC 3.6.1.-).

SELO_HUMAN
NC score	0.023211 (rank : 121)	θ value	6.88961 (rank : 91)
Query Neighborhood Hits	109	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BVL4, Q8WUI0	Gene names	SELO
Domain Architecture
Description	Selenoprotein O.

BFSP2_HUMAN
NC score	0.022156 (rank : 122)	θ value	0.62314 (rank : 22)
Query Neighborhood Hits	109	Target Neighborhood Hits	348	Shared Neighborhood Hits	11
SwissProt Accessions	Q13515, Q9HBW5	Gene names	BFSP2
Domain Architecture
Description	Phakinin (Beaded filament structural protein 2) (Lens fiber cell beaded filament protein CP 49) (CP49) (49 kDa cytoskeletal protein) (CP 47) (CP47) (Lens intermediate filament-like light) (LIFL-L).

NALP7_HUMAN
NC score	0.021475 (rank : 123)	θ value	5.27518 (rank : 80)
Query Neighborhood Hits	109	Target Neighborhood Hits	65	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WX94, Q7RTR1	Gene names	NALP7, NOD12, PYPAF3
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 7 (PYRIN-containing APAF1-like protein 3).

HECD1_HUMAN
NC score	0.020892 (rank : 124)	θ value	2.36792 (rank : 51)
Query Neighborhood Hits	109	Target Neighborhood Hits	371	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ULT8, Q6P445, Q86VJ1, Q96F34, Q9UFZ7	Gene names	HECTD1, KIAA1131
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase HECTD1 (HECT domain-containing protein 1) (E3 ligase for inhibin receptor) (EULIR).

AKAP8_MOUSE
NC score	0.019777 (rank : 125)	θ value	6.88961 (rank : 83)
Query Neighborhood Hits	109	Target Neighborhood Hits	76	Shared Neighborhood Hits	4
SwissProt Accessions	Q9DBR0, Q9R0L8	Gene names	Akap8, Akap95
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 8 (A-kinase anchor protein 95 kDa) (AKAP 95).

ESCO2_MOUSE
NC score	0.019714 (rank : 126)	θ value	6.88961 (rank : 87)
Query Neighborhood Hits	109	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CIB9, Q3UMT6, Q6IQX5, Q8BNG9, Q8BQF8, Q9CRI8	Gene names	Esco2
Domain Architecture	No domain graphic available
Description	N-acetyltransferase ESCO2 (EC 2.3.1.-) (Establishment of cohesion 1 homolog 2) (ECO1 homolog 2).

ROCK2_MOUSE
NC score	0.018315 (rank : 127)	θ value	2.36792 (rank : 52)
Query Neighborhood Hits	109	Target Neighborhood Hits	2072	Shared Neighborhood Hits	44
SwissProt Accessions	P70336, Q8BR64, Q8CBR0	Gene names	Rock2
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2).

DNJA1_MOUSE
NC score	0.017839 (rank : 128)	θ value	5.27518 (rank : 77)
Query Neighborhood Hits	109	Target Neighborhood Hits	83	Shared Neighborhood Hits	4
SwissProt Accessions	P63037, P54102	Gene names	Dnaja1, Dnaj2, Hsj2, Hspf4
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily A member 1 (Heat shock 40 kDa protein 4) (DnaJ protein homolog 2) (HSJ-2).

DNJA1_HUMAN
NC score	0.017728 (rank : 129)	θ value	5.27518 (rank : 76)
Query Neighborhood Hits	109	Target Neighborhood Hits	84	Shared Neighborhood Hits	4
SwissProt Accessions	P31689	Gene names	DNAJA1, DNAJ2, HDJ2, HSJ2, HSPF4
Domain Architecture
Description	DnaJ homolog subfamily A member 1 (Heat shock 40 kDa protein 4) (DnaJ protein homolog 2) (HSJ-2) (HSDJ).

LIMA1_HUMAN
NC score	0.017624 (rank : 130)	θ value	8.99809 (rank : 99)
Query Neighborhood Hits	109	Target Neighborhood Hits	309	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UHB6, Q2TAN7, Q9BVF2, Q9H8J1, Q9HBN5, Q9NX96, Q9NXC3, Q9NXU6, Q9P0H8, Q9UHB5	Gene names	LIMA1, EPLIN, SREBP3
Domain Architecture
Description	LIM domain and actin-binding protein 1 (Epithelial protein lost in neoplasm).

CASQ1_HUMAN
NC score	0.017403 (rank : 131)	θ value	6.88961 (rank : 84)
Query Neighborhood Hits	109	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	P31415, Q8TBW7	Gene names	CASQ1, CASQ
Domain Architecture
Description	Calsequestrin-1 precursor (Calsequestrin, skeletal muscle isoform) (Calmitin).

VAV_HUMAN
NC score	0.016454 (rank : 132)	θ value	3.0926 (rank : 67)
Query Neighborhood Hits	109	Target Neighborhood Hits	452	Shared Neighborhood Hits	9
SwissProt Accessions	P15498, Q15860	Gene names	VAV1, VAV
Domain Architecture
Description	Proto-oncogene vav.

E41L1_HUMAN
NC score	0.014329 (rank : 133)	θ value	3.0926 (rank : 60)
Query Neighborhood Hits	109	Target Neighborhood Hits	180	Shared Neighborhood Hits	11
SwissProt Accessions	Q9H4G0, O15046, Q4VXN4	Gene names	EPB41L1, KIAA0338
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).

TAOK1_MOUSE
NC score	0.013052 (rank : 134)	θ value	3.0926 (rank : 65)
Query Neighborhood Hits	109	Target Neighborhood Hits	1720	Shared Neighborhood Hits	32
SwissProt Accessions	Q5F2E8, Q69ZL2, Q8JZX2, Q91VG7	Gene names	Taok1, Kiaa1361
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Thousand and one amino acid protein 1).

TAOK1_HUMAN
NC score	0.012215 (rank : 135)	θ value	5.27518 (rank : 82)
Query Neighborhood Hits	109	Target Neighborhood Hits	1734	Shared Neighborhood Hits	33
SwissProt Accessions	Q7L7X3, Q96L75, Q9H2K7, Q9H7S5, Q9P2I6	Gene names	TAOK1, KIAA1361, MAP3K16
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Thousand and one amino acid protein 1) (STE20-like kinase PSK2) (Kinase from chicken homolog B) (hKFC-B).

UBP25_MOUSE
NC score	0.012143 (rank : 136)	θ value	8.99809 (rank : 107)
Query Neighborhood Hits	109	Target Neighborhood Hits	116	Shared Neighborhood Hits	5
SwissProt Accessions	P57080, Q80ZT9	Gene names	Usp25
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 25 (EC 3.1.2.15) (Ubiquitin thioesterase 25) (Ubiquitin-specific-processing protease 25) (Deubiquitinating enzyme 25) (mUSP25).

SRGP2_HUMAN
NC score	0.011551 (rank : 137)	θ value	8.99809 (rank : 105)
Query Neighborhood Hits	109	Target Neighborhood Hits	331	Shared Neighborhood Hits	8
SwissProt Accessions	O43295, Q8IX13, Q8IZV8	Gene names	SRGAP3, ARHGAP14, KIAA0411, MEGAP, SRGAP2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Mental disorder- associated GAP) (Rho-GTPase-activating protein 14).

LAMB2_MOUSE
NC score	0.009191 (rank : 138)	θ value	4.03905 (rank : 70)
Query Neighborhood Hits	109	Target Neighborhood Hits	722	Shared Neighborhood Hits	11
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

LAP2_HUMAN
NC score	0.008806 (rank : 139)	θ value	5.27518 (rank : 79)
Query Neighborhood Hits	109	Target Neighborhood Hits	499	Shared Neighborhood Hits	8
SwissProt Accessions	Q96RT1, Q86W38, Q9NR18, Q9NW48, Q9ULJ5	Gene names	ERBB2IP, ERBIN, KIAA1225, LAP2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

PEPP2_HUMAN
NC score	0.007241 (rank : 140)	θ value	8.99809 (rank : 101)
Query Neighborhood Hits	109	Target Neighborhood Hits	316	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BQY4, Q9BR00	Gene names	PEPP2, THG1
Domain Architecture
Description	Paired-like homeobox protein PEPP-2 (Testis homeobox gene 1).

SPB13_HUMAN
NC score	0.006823 (rank : 141)	θ value	5.27518 (rank : 81)
Query Neighborhood Hits	109	Target Neighborhood Hits	97	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UIV8, Q9HCX1, Q9UBW1, Q9UKG0	Gene names	SERPINB13, PI13
Domain Architecture
Description	Serpin B13 (Hurpin) (HaCaT UV-repressible serpin) (Protease inhibitor 13) (Headpin).

PRP4_MOUSE
NC score	0.006081 (rank : 142)	θ value	6.88961 (rank : 89)
Query Neighborhood Hits	109	Target Neighborhood Hits	308	Shared Neighborhood Hits	3
SwissProt Accessions	Q9DAW6	Gene names	Prpf4
Domain Architecture	No domain graphic available
Description	U4/U6 small nuclear ribonucleoprotein Prp4 (U4/U6 snRNP 60 kDa protein) (WD splicing factor Prp4).

RB39B_MOUSE
NC score	0.003595 (rank : 143)	θ value	8.99809 (rank : 103)
Query Neighborhood Hits	109	Target Neighborhood Hits	277	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BHC1, Q3TUJ3	Gene names	Rab39b
Domain Architecture
Description	Ras-related protein Rab-39B.

RB39B_HUMAN
NC score	0.003556 (rank : 144)	θ value	8.99809 (rank : 102)
Query Neighborhood Hits	109	Target Neighborhood Hits	279	Shared Neighborhood Hits	3
SwissProt Accessions	Q96DA2, Q5JT79, Q8NEX3	Gene names	RAB39B
Domain Architecture
Description	Ras-related protein Rab-39B.