Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : PAPPA_MOUSE

For an explanation of this page, click here

PAPPA_MOUSE
SwissProt Accessions	Q8R4K8, Q80VW3, Q80YY1, Q8K423, Q8R4K7, Q9ES06, Q9JK57	Gene names	Pappa
Domain Architecture	No domain graphic available
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PAP2_HUMAN
θ value	0 (rank : 1)	NC score	0.951476 (rank : 3)
Query Neighborhood Hits	153	Target Neighborhood Hits	106	Shared Neighborhood Hits	69
SwissProt Accessions	Q9BXP8, Q96PH7, Q96PH8, Q9H4C9	Gene names	PAPPA2
Domain Architecture	No domain graphic available
Description	Pappalysin-2 precursor (EC 3.4.24.-) (Pregnancy-associated plasma protein-A2) (PAPP-A2) (Pregnancy-associated plasma protein-E1) (PAPP- E).

PAPPA_HUMAN
θ value	0 (rank : 2)	NC score	0.986435 (rank : 2)
Query Neighborhood Hits	153	Target Neighborhood Hits	161	Shared Neighborhood Hits	120
SwissProt Accessions	Q13219, Q08371, Q68G52, Q9UDK7	Gene names	PAPPA
Domain Architecture
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

PAPPA_MOUSE
θ value	0 (rank : 3)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	153	Target Neighborhood Hits	153	Shared Neighborhood Hits	153
SwissProt Accessions	Q8R4K8, Q80VW3, Q80YY1, Q8K423, Q8R4K7, Q9ES06, Q9JK57	Gene names	Pappa
Domain Architecture	No domain graphic available
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

LYAM3_HUMAN
θ value	2.5182e-18 (rank : 4)	NC score	0.568108 (rank : 8)
Query Neighborhood Hits	153	Target Neighborhood Hits	378	Shared Neighborhood Hits	99
SwissProt Accessions	P16109, Q8IVD1	Gene names	SELP, GMRP
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

LYAM2_HUMAN
θ value	4.29542e-18 (rank : 5)	NC score	0.554102 (rank : 15)
Query Neighborhood Hits	153	Target Neighborhood Hits	394	Shared Neighborhood Hits	96
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

CSMD1_HUMAN
θ value	8.10077e-17 (rank : 6)	NC score	0.473211 (rank : 32)
Query Neighborhood Hits	153	Target Neighborhood Hits	176	Shared Neighborhood Hits	66
SwissProt Accessions	Q96PZ7, Q96QU9, Q96RM4	Gene names	CSMD1, KIAA1890
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

CSMD1_MOUSE
θ value	8.10077e-17 (rank : 7)	NC score	0.475194 (rank : 31)
Query Neighborhood Hits	153	Target Neighborhood Hits	193	Shared Neighborhood Hits	68
SwissProt Accessions	Q923L3, Q8BUV1, Q8BYQ3	Gene names	Csmd1
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

LYAM3_MOUSE
θ value	5.25075e-16 (rank : 8)	NC score	0.560967 (rank : 11)
Query Neighborhood Hits	153	Target Neighborhood Hits	390	Shared Neighborhood Hits	102
SwissProt Accessions	Q01102	Gene names	Selp, Grmp
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

LYAM2_MOUSE
θ value	2.20605e-14 (rank : 9)	NC score	0.540827 (rank : 21)
Query Neighborhood Hits	153	Target Neighborhood Hits	420	Shared Neighborhood Hits	100
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

DAF1_MOUSE
θ value	4.91457e-14 (rank : 10)	NC score	0.609093 (rank : 5)
Query Neighborhood Hits	153	Target Neighborhood Hits	204	Shared Neighborhood Hits	59
SwissProt Accessions	Q61475, P97732, Q61397	Gene names	Cd55a, Daf1
Domain Architecture
Description	Complement decay-accelerating factor, GPI-anchored precursor (DAF-GPI) (CD55 antigen).

CSMD2_HUMAN
θ value	1.42992e-13 (rank : 11)	NC score	0.461781 (rank : 35)
Query Neighborhood Hits	153	Target Neighborhood Hits	188	Shared Neighborhood Hits	63
SwissProt Accessions	Q7Z408, Q5VT59, Q8N963, Q96Q03, Q9H4V7, Q9H4V8, Q9H4V9, Q9H4W0, Q9H4W1, Q9H4W2, Q9H4W3, Q9H4W4, Q9HCY5, Q9HCY6, Q9HCY7	Gene names	CSMD2, KIAA1884
Domain Architecture
Description	CUB and sushi domain-containing protein 2 (CUB and sushi multiple domains protein 2).

CSMD3_HUMAN
θ value	1.42992e-13 (rank : 12)	NC score	0.471202 (rank : 34)
Query Neighborhood Hits	153	Target Neighborhood Hits	199	Shared Neighborhood Hits	66
SwissProt Accessions	Q7Z407, Q96PZ3	Gene names	CSMD3, KIAA1894
Domain Architecture
Description	CUB and sushi domain-containing protein 3 precursor (CUB and sushi multiple domains protein 3).

DAF2_MOUSE
θ value	7.09661e-13 (rank : 13)	NC score	0.612051 (rank : 4)
Query Neighborhood Hits	153	Target Neighborhood Hits	114	Shared Neighborhood Hits	58
SwissProt Accessions	Q61476	Gene names	Cd55b, Daf2
Domain Architecture
Description	Complement decay-accelerating factor transmembrane isoform precursor (DAF-TM) (CD55 antigen).

CFAH_MOUSE
θ value	6.00763e-12 (rank : 14)	NC score	0.545714 (rank : 17)
Query Neighborhood Hits	153	Target Neighborhood Hits	112	Shared Neighborhood Hits	62
SwissProt Accessions	P06909	Gene names	Cfh, Hf1
Domain Architecture
Description	Complement factor H precursor (Protein beta-1-H).

DAF_HUMAN
θ value	1.33837e-11 (rank : 15)	NC score	0.603424 (rank : 6)
Query Neighborhood Hits	153	Target Neighborhood Hits	97	Shared Neighborhood Hits	57
SwissProt Accessions	P08174, P09679, P78361	Gene names	CD55, CR, DAF
Domain Architecture
Description	Complement decay-accelerating factor precursor (CD55 antigen).

CR1_HUMAN
θ value	3.89403e-11 (rank : 16)	NC score	0.569973 (rank : 7)
Query Neighborhood Hits	153	Target Neighborhood Hits	108	Shared Neighborhood Hits	61
SwissProt Accessions	P17927, Q16745, Q9UQV2	Gene names	CR1, C3BR
Domain Architecture
Description	Complement receptor type 1 precursor (C3b/C4b receptor) (CD35 antigen).

CR2_HUMAN
θ value	1.63604e-09 (rank : 17)	NC score	0.562105 (rank : 10)
Query Neighborhood Hits	153	Target Neighborhood Hits	89	Shared Neighborhood Hits	58
SwissProt Accessions	P20023, Q13866, Q14212	Gene names	CR2, C3DR
Domain Architecture
Description	Complement receptor type 2 precursor (Cr2) (Complement C3d receptor) (Epstein-Barr virus receptor) (EBV receptor) (CD21 antigen).

SRPX_HUMAN
θ value	2.79066e-09 (rank : 18)	NC score	0.541868 (rank : 20)
Query Neighborhood Hits	153	Target Neighborhood Hits	69	Shared Neighborhood Hits	52
SwissProt Accessions	P78539, Q99652, Q99913	Gene names	SRPX, ETX1
Domain Architecture
Description	Sushi repeat-containing protein SRPX precursor.

C4BP_HUMAN
θ value	6.21693e-09 (rank : 19)	NC score	0.559146 (rank : 13)
Query Neighborhood Hits	153	Target Neighborhood Hits	92	Shared Neighborhood Hits	59
SwissProt Accessions	P04003	Gene names	C4BPA, C4BP
Domain Architecture
Description	C4b-binding protein alpha chain precursor (C4bp) (Proline-rich protein) (PRP).

APOH_MOUSE
θ value	1.80886e-08 (rank : 20)	NC score	0.558787 (rank : 14)
Query Neighborhood Hits	153	Target Neighborhood Hits	74	Shared Neighborhood Hits	58
SwissProt Accessions	Q01339	Gene names	Apoh, B2gp1
Domain Architecture
Description	Beta-2-glycoprotein 1 precursor (Beta-2-glycoprotein I) (Apolipoprotein H) (Apo-H) (B2GPI) (Beta(2)GPI) (Activated protein C- binding protein) (APC inhibitor).

CFAH_HUMAN
θ value	1.80886e-08 (rank : 21)	NC score	0.529648 (rank : 23)
Query Neighborhood Hits	153	Target Neighborhood Hits	101	Shared Neighborhood Hits	62
SwissProt Accessions	P08603, P78435, Q14570, Q38G77, Q5TFM3, Q8N708, Q9NU86	Gene names	CFH, HF, HF1
Domain Architecture
Description	Complement factor H precursor (H factor 1).

ZP3R_MOUSE
θ value	1.80886e-08 (rank : 22)	NC score	0.565445 (rank : 9)
Query Neighborhood Hits	153	Target Neighborhood Hits	81	Shared Neighborhood Hits	57
SwissProt Accessions	Q60736	Gene names	Zp3r, Sp56
Domain Architecture
Description	Zona pellucida sperm-binding protein 3 receptor precursor (Sperm fertilization protein 56) (sp56).

SRPX_MOUSE
θ value	2.36244e-08 (rank : 23)	NC score	0.542376 (rank : 19)
Query Neighborhood Hits	153	Target Neighborhood Hits	75	Shared Neighborhood Hits	54
SwissProt Accessions	Q9R0M3, Q9R0M2	Gene names	Srpx
Domain Architecture	No domain graphic available
Description	Sushi-repeat-containing protein SRPX precursor (DRS protein).

CR2_MOUSE
θ value	3.08544e-08 (rank : 24)	NC score	0.560921 (rank : 12)
Query Neighborhood Hits	153	Target Neighborhood Hits	101	Shared Neighborhood Hits	60
SwissProt Accessions	P19070	Gene names	Cr2
Domain Architecture
Description	Complement receptor type 2 precursor (Cr2) (Complement C3d receptor) (CD21 antigen).

FHR1_HUMAN
θ value	8.97725e-08 (rank : 25)	NC score	0.477171 (rank : 30)
Query Neighborhood Hits	153	Target Neighborhood Hits	80	Shared Neighborhood Hits	57
SwissProt Accessions	Q03591, Q9UJ17	Gene names	CFHL1, CFHL, FHR1, HFL1
Domain Architecture
Description	Complement factor H-related protein 1 precursor (FHR-1) (H factor-like protein 1) (H-factor-like 1) (H36).

CRRY_MOUSE
θ value	4.45536e-07 (rank : 26)	NC score	0.550315 (rank : 16)
Query Neighborhood Hits	153	Target Neighborhood Hits	84	Shared Neighborhood Hits	57
SwissProt Accessions	Q64735, Q3TV30, Q58E68, Q61447, Q61449, Q8CF59, Q8K328	Gene names	Crry, Cry
Domain Architecture	No domain graphic available
Description	Complement regulatory protein Crry precursor (Protein p65).

LYAM1_MOUSE
θ value	4.45536e-07 (rank : 27)	NC score	0.433922 (rank : 39)
Query Neighborhood Hits	153	Target Neighborhood Hits	332	Shared Neighborhood Hits	84
SwissProt Accessions	P18337	Gene names	Sell, Lnhr, Ly-22
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Lymphocyte antigen 22) (Ly-22) (Lymphocyte surface MEL-14 antigen) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

MEGF6_HUMAN
θ value	1.69304e-06 (rank : 28)	NC score	0.140439 (rank : 63)
Query Neighborhood Hits	153	Target Neighborhood Hits	671	Shared Neighborhood Hits	82
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

CO2_HUMAN
θ value	2.21117e-06 (rank : 29)	NC score	0.313255 (rank : 43)
Query Neighborhood Hits	153	Target Neighborhood Hits	258	Shared Neighborhood Hits	56
SwissProt Accessions	P06681, O19694, Q13904	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

FHR2_HUMAN
θ value	2.21117e-06 (rank : 30)	NC score	0.453822 (rank : 36)
Query Neighborhood Hits	153	Target Neighborhood Hits	63	Shared Neighborhood Hits	52
SwissProt Accessions	P36980, Q14310	Gene names	CFHL2, FHR2, HFL3
Domain Architecture
Description	Complement factor H-related protein 2 precursor (FHR-2) (H factor-like protein 2) (H factor-like 3) (DDESK59).

F13B_MOUSE
θ value	3.77169e-06 (rank : 31)	NC score	0.520499 (rank : 24)
Query Neighborhood Hits	153	Target Neighborhood Hits	93	Shared Neighborhood Hits	62
SwissProt Accessions	Q07968	Gene names	F13b, Cf13b
Domain Architecture
Description	Coagulation factor XIII B chain precursor (Protein-glutamine gamma- glutamyltransferase B chain) (Transglutaminase B chain).

F13B_HUMAN
θ value	6.43352e-06 (rank : 32)	NC score	0.514531 (rank : 25)
Query Neighborhood Hits	153	Target Neighborhood Hits	84	Shared Neighborhood Hits	54
SwissProt Accessions	P05160	Gene names	F13B
Domain Architecture
Description	Coagulation factor XIII B chain precursor (Protein-glutamine gamma- glutamyltransferase B chain) (Transglutaminase B chain) (Fibrin- stabilizing factor B subunit).

SUSD1_HUMAN
θ value	1.09739e-05 (rank : 33)	NC score	0.285845 (rank : 44)
Query Neighborhood Hits	153	Target Neighborhood Hits	285	Shared Neighborhood Hits	82
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

FHR5_HUMAN
θ value	1.43324e-05 (rank : 34)	NC score	0.481578 (rank : 28)
Query Neighborhood Hits	153	Target Neighborhood Hits	77	Shared Neighborhood Hits	54
SwissProt Accessions	Q9BXR6	Gene names	CFHL5, FHR5
Domain Architecture
Description	Complement factor H-related protein 5 precursor (FHR-5).

MASP2_MOUSE
θ value	1.43324e-05 (rank : 35)	NC score	0.173412 (rank : 53)
Query Neighborhood Hits	153	Target Neighborhood Hits	382	Shared Neighborhood Hits	79
SwissProt Accessions	Q91WP0, Q9QXA4, Q9QXD2, Q9QXD5, Q9Z338	Gene names	Masp2
Domain Architecture	No domain graphic available
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

SREC2_MOUSE
θ value	3.19293e-05 (rank : 36)	NC score	0.140030 (rank : 64)
Query Neighborhood Hits	153	Target Neighborhood Hits	605	Shared Neighborhood Hits	67
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

C1S_HUMAN
θ value	5.44631e-05 (rank : 37)	NC score	0.163742 (rank : 54)
Query Neighborhood Hits	153	Target Neighborhood Hits	359	Shared Neighborhood Hits	74
SwissProt Accessions	P09871, Q9UCU7, Q9UCU8, Q9UCU9, Q9UCV0, Q9UCV1, Q9UCV2, Q9UCV3, Q9UCV4, Q9UCV5, Q9UM14	Gene names	C1S
Domain Architecture
Description	Complement C1s subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s subcomponent heavy chain; Complement C1s subcomponent light chain].

LYAM1_HUMAN
θ value	5.44631e-05 (rank : 38)	NC score	0.418749 (rank : 41)
Query Neighborhood Hits	153	Target Neighborhood Hits	315	Shared Neighborhood Hits	85
SwissProt Accessions	P14151, P15023	Gene names	SELL, LNHR, LYAM1
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Leukocyte surface antigen Leu-8) (TQ1) (gp90-MEL) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

SUSD4_HUMAN
θ value	0.00020696 (rank : 39)	NC score	0.471505 (rank : 33)
Query Neighborhood Hits	153	Target Neighborhood Hits	88	Shared Neighborhood Hits	52
SwissProt Accessions	Q5VX71, Q6UX62, Q9BSR0, Q9NWG0	Gene names	SUSD4
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 4 precursor.

C4BP_MOUSE
θ value	0.000461057 (rank : 40)	NC score	0.543805 (rank : 18)
Query Neighborhood Hits	153	Target Neighborhood Hits	91	Shared Neighborhood Hits	57
SwissProt Accessions	P08607	Gene names	C4bpa, C4bp
Domain Architecture
Description	C4b-binding protein precursor (C4bp).

C4BB_HUMAN
θ value	0.000786445 (rank : 41)	NC score	0.540518 (rank : 22)
Query Neighborhood Hits	153	Target Neighborhood Hits	77	Shared Neighborhood Hits	56
SwissProt Accessions	P20851	Gene names	C4BPB
Domain Architecture
Description	C4b-binding protein beta chain precursor.

CO2_MOUSE
θ value	0.000786445 (rank : 42)	NC score	0.252069 (rank : 47)
Query Neighborhood Hits	153	Target Neighborhood Hits	250	Shared Neighborhood Hits	56
SwissProt Accessions	P21180	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

MASP2_HUMAN
θ value	0.000786445 (rank : 43)	NC score	0.155106 (rank : 55)
Query Neighborhood Hits	153	Target Neighborhood Hits	364	Shared Neighborhood Hits	76
SwissProt Accessions	O00187, O75754, Q5TEQ5, Q5TER0, Q96QG4, Q9BZH0, Q9H498, Q9H499, Q9UBP3, Q9ULC7, Q9UMV3, Q9Y270	Gene names	MASP2
Domain Architecture
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

MCP_MOUSE
θ value	0.00134147 (rank : 44)	NC score	0.494882 (rank : 27)
Query Neighborhood Hits	153	Target Neighborhood Hits	79	Shared Neighborhood Hits	57
SwissProt Accessions	O88174, Q9R0R9	Gene names	Cd46, Mcp
Domain Architecture	No domain graphic available
Description	Membrane cofactor protein precursor (CD46 antigen).

FHR3_HUMAN
θ value	0.00298849 (rank : 45)	NC score	0.441933 (rank : 38)
Query Neighborhood Hits	153	Target Neighborhood Hits	74	Shared Neighborhood Hits	57
SwissProt Accessions	Q02985, Q9UJ16	Gene names	CFHL3, FHR3
Domain Architecture
Description	Complement factor H-related protein 3 precursor (FHR-3) (H factor-like protein 3) (DOWN16).

SREC2_HUMAN
θ value	0.00390308 (rank : 46)	NC score	0.122071 (rank : 77)
Query Neighborhood Hits	153	Target Neighborhood Hits	645	Shared Neighborhood Hits	69
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

NOTC3_HUMAN
θ value	0.00665767 (rank : 47)	NC score	0.114921 (rank : 85)
Query Neighborhood Hits	153	Target Neighborhood Hits	1062	Shared Neighborhood Hits	85
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

CS1B_MOUSE
θ value	0.00869519 (rank : 48)	NC score	0.144713 (rank : 58)
Query Neighborhood Hits	153	Target Neighborhood Hits	361	Shared Neighborhood Hits	74
SwissProt Accessions	Q8CFG8	Gene names	C1sb, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-B subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-B subcomponent heavy chain; Complement C1s-B subcomponent light chain].

MASP1_MOUSE
θ value	0.00869519 (rank : 49)	NC score	0.132862 (rank : 66)
Query Neighborhood Hits	153	Target Neighborhood Hits	364	Shared Neighborhood Hits	76
SwissProt Accessions	P98064	Gene names	Masp1, Crarf
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) [Contains: Complement- activating component of Ra-reactive factor heavy chain; Complement- activating component of Ra-reactive factor light chain].

FHR4_HUMAN
θ value	0.0113563 (rank : 50)	NC score	0.425965 (rank : 40)
Query Neighborhood Hits	153	Target Neighborhood Hits	75	Shared Neighborhood Hits	54
SwissProt Accessions	Q92496, Q9UJY6	Gene names	CFHL4, FHR4
Domain Architecture
Description	Complement factor H-related protein 4 precursor (FHR-4).

SEZ6L_HUMAN
θ value	0.0113563 (rank : 51)	NC score	0.399378 (rank : 42)
Query Neighborhood Hits	153	Target Neighborhood Hits	289	Shared Neighborhood Hits	55
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.

GNPTA_MOUSE
θ value	0.0148317 (rank : 52)	NC score	0.129654 (rank : 69)
Query Neighborhood Hits	153	Target Neighborhood Hits	47	Shared Neighborhood Hits	15
SwissProt Accessions	Q69ZN6, Q3U3K6, Q3US34	Gene names	Gnptab, Gnpta, Kiaa1208
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphotransferase subunits alpha/beta precursor (EC 2.7.8.17) (GlcNAc-1-phosphotransferase alpha/beta subunits) (UDP- N-acetylglucosamine-1-phosphotransferase alpha/beta subunits) (Stealth protein GNPTAB) [Contains: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta].

NOTC3_MOUSE
θ value	0.0148317 (rank : 53)	NC score	0.116931 (rank : 84)
Query Neighborhood Hits	153	Target Neighborhood Hits	975	Shared Neighborhood Hits	85
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

SREC_HUMAN
θ value	0.0148317 (rank : 54)	NC score	0.121147 (rank : 78)
Query Neighborhood Hits	153	Target Neighborhood Hits	645	Shared Neighborhood Hits	69
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

USH2A_MOUSE
θ value	0.0148317 (rank : 55)	NC score	0.078050 (rank : 177)
Query Neighborhood Hits	153	Target Neighborhood Hits	626	Shared Neighborhood Hits	63
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

KR107_HUMAN
θ value	0.0193708 (rank : 56)	NC score	0.141506 (rank : 61)
Query Neighborhood Hits	153	Target Neighborhood Hits	330	Shared Neighborhood Hits	60
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

APOH_HUMAN
θ value	0.0252991 (rank : 57)	NC score	0.514007 (rank : 26)
Query Neighborhood Hits	153	Target Neighborhood Hits	75	Shared Neighborhood Hits	56
SwissProt Accessions	P02749, Q9UCN7	Gene names	APOH, B2G1
Domain Architecture
Description	Beta-2-glycoprotein 1 precursor (Beta-2-glycoprotein I) (Apolipoprotein H) (Apo-H) (B2GPI) (Beta(2)GPI) (Activated protein C- binding protein) (APC inhibitor) (Anticardiolipin cofactor).

LTBP4_MOUSE
θ value	0.0330416 (rank : 58)	NC score	0.112793 (rank : 87)
Query Neighborhood Hits	153	Target Neighborhood Hits	607	Shared Neighborhood Hits	75
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

CS1A_MOUSE
θ value	0.0431538 (rank : 59)	NC score	0.143408 (rank : 59)
Query Neighborhood Hits	153	Target Neighborhood Hits	360	Shared Neighborhood Hits	74
SwissProt Accessions	Q8CG14, Q8BJC4, Q8CH28, Q8VBY4	Gene names	C1sa, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-A subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-A subcomponent heavy chain; Complement C1s-A subcomponent light chain].

GNPTA_HUMAN
θ value	0.0431538 (rank : 60)	NC score	0.122864 (rank : 75)
Query Neighborhood Hits	153	Target Neighborhood Hits	43	Shared Neighborhood Hits	16
SwissProt Accessions	Q3T906, Q3ZQK2, Q6IPW5, Q86TQ2, Q96N13, Q9ULL2	Gene names	GNPTAB, GNPTA, KIAA1208
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphotransferase subunits alpha/beta precursor (EC 2.7.8.17) (GlcNAc-1-phosphotransferase alpha/beta subunits) (UDP- N-acetylglucosamine-1-phosphotransferase alpha/beta subunits) (Stealth protein GNPTAB) [Contains: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta].

CFAB_HUMAN
θ value	0.0563607 (rank : 61)	NC score	0.267251 (rank : 46)
Query Neighborhood Hits	153	Target Neighborhood Hits	251	Shared Neighborhood Hits	56
SwissProt Accessions	P00751, O15006, Q29944, Q96HX6, Q9BTF5, Q9BX92	Gene names	CFB, BF
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) (Properdin factor B) (Glycine-rich beta glycoprotein) (GBG) (PBF2) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

CFAB_MOUSE
θ value	0.0736092 (rank : 62)	NC score	0.270477 (rank : 45)
Query Neighborhood Hits	153	Target Neighborhood Hits	262	Shared Neighborhood Hits	56
SwissProt Accessions	P04186	Gene names	Cfb, Bf, H2-Bf
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

FBLN1_MOUSE
θ value	0.0736092 (rank : 63)	NC score	0.100359 (rank : 113)
Query Neighborhood Hits	153	Target Neighborhood Hits	329	Shared Neighborhood Hits	63
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

NOTC1_MOUSE
θ value	0.0736092 (rank : 64)	NC score	0.117740 (rank : 83)
Query Neighborhood Hits	153	Target Neighborhood Hits	916	Shared Neighborhood Hits	85
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

SSPO_MOUSE
θ value	0.0736092 (rank : 65)	NC score	0.077099 (rank : 180)
Query Neighborhood Hits	153	Target Neighborhood Hits	800	Shared Neighborhood Hits	72
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

PTX3_MOUSE
θ value	0.0961366 (rank : 66)	NC score	0.036679 (rank : 346)
Query Neighborhood Hits	153	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	P48759, Q8VDF1	Gene names	Ptx3, Tsg14
Domain Architecture
Description	Pentraxin-related protein PTX3 precursor (Pentaxin-related protein PTX3) (Tumor necrosis factor-inducible protein TSG-14).

SUSD4_MOUSE
θ value	0.0961366 (rank : 67)	NC score	0.449887 (rank : 37)
Query Neighborhood Hits	153	Target Neighborhood Hits	122	Shared Neighborhood Hits	52
SwissProt Accessions	Q8BH32, Q8VC43	Gene names	Susd4
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 4 precursor.

CO6_HUMAN
θ value	0.125558 (rank : 68)	NC score	0.201424 (rank : 51)
Query Neighborhood Hits	153	Target Neighborhood Hits	331	Shared Neighborhood Hits	84
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

KR10B_HUMAN
θ value	0.125558 (rank : 69)	NC score	0.126031 (rank : 74)
Query Neighborhood Hits	153	Target Neighborhood Hits	269	Shared Neighborhood Hits	51
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

PTPRB_HUMAN
θ value	0.125558 (rank : 70)	NC score	0.015259 (rank : 361)
Query Neighborhood Hits	153	Target Neighborhood Hits	242	Shared Neighborhood Hits	6
SwissProt Accessions	P23467	Gene names	PTPRB, PTPB
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase beta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase beta) (R-PTP-beta).

MCP_HUMAN
θ value	0.163984 (rank : 71)	NC score	0.479214 (rank : 29)
Query Neighborhood Hits	153	Target Neighborhood Hits	82	Shared Neighborhood Hits	56
SwissProt Accessions	P15529, Q15429, Q53GV9, Q5HY94, Q5VWS6, Q5VWS7, Q5VWS8, Q5VWS9, Q5VWT0, Q5VWT1, Q5VWT2, Q6N0A1, Q7Z3R5, Q9NNW2, Q9NNW3, Q9NNW4	Gene names	CD46, MCP
Domain Architecture
Description	Membrane cofactor protein precursor (Trophoblast leukocyte common antigen) (TLX) (CD46 antigen).

NOTC1_HUMAN
θ value	0.163984 (rank : 72)	NC score	0.111372 (rank : 90)
Query Neighborhood Hits	153	Target Neighborhood Hits	906	Shared Neighborhood Hits	85
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

COLQ_HUMAN
θ value	0.21417 (rank : 73)	NC score	0.033688 (rank : 347)
Query Neighborhood Hits	153	Target Neighborhood Hits	193	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y215, Q6DK18, Q6YH18, Q6YH19, Q6YH20, Q6YH21, Q9NP18, Q9NP19, Q9NP20, Q9NP21, Q9NP22, Q9NP23, Q9NP24, Q9UP88	Gene names	COLQ
Domain Architecture	No domain graphic available
Description	Acetylcholinesterase collagenic tail peptide precursor (AChE Q subunit) (Acetylcholinesterase-associated collagen).

DLL1_MOUSE
θ value	0.21417 (rank : 74)	NC score	0.094037 (rank : 125)
Query Neighborhood Hits	153	Target Neighborhood Hits	456	Shared Neighborhood Hits	71
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

KR109_HUMAN
θ value	0.21417 (rank : 75)	NC score	0.128366 (rank : 71)
Query Neighborhood Hits	153	Target Neighborhood Hits	226	Shared Neighborhood Hits	47
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

ZAN_MOUSE
θ value	0.21417 (rank : 76)	NC score	0.122322 (rank : 76)
Query Neighborhood Hits	153	Target Neighborhood Hits	808	Shared Neighborhood Hits	81
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

CMGA_MOUSE
θ value	0.279714 (rank : 77)	NC score	0.059578 (rank : 272)
Query Neighborhood Hits	153	Target Neighborhood Hits	172	Shared Neighborhood Hits	3
SwissProt Accessions	P26339	Gene names	Chga
Domain Architecture
Description	Chromogranin A precursor (CgA) [Contains: Pancreastatin; Beta-granin; WE-14].

DLL1_HUMAN
θ value	0.279714 (rank : 78)	NC score	0.093994 (rank : 126)
Query Neighborhood Hits	153	Target Neighborhood Hits	455	Shared Neighborhood Hits	69
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

LIPE_HUMAN
θ value	0.279714 (rank : 79)	NC score	0.020699 (rank : 359)
Query Neighborhood Hits	153	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y5X9, Q6UW82	Gene names	LIPG
Domain Architecture
Description	Endothelial lipase precursor (EC 3.1.1.3) (Endothelial cell-derived lipase) (EDL) (EL).

MASP1_HUMAN
θ value	0.279714 (rank : 80)	NC score	0.141076 (rank : 62)
Query Neighborhood Hits	153	Target Neighborhood Hits	369	Shared Neighborhood Hits	77
SwissProt Accessions	P48740, O95570, Q9UF09	Gene names	MASP1, CRARF, CRARF1, PRSS5
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) (Mannose-binding protein- associated serine protease) (MASP-1) [Contains: Complement-activating component of Ra-reactive factor heavy chain; Complement-activating component of Ra-reactive factor light chain].

KR106_HUMAN
θ value	0.365318 (rank : 81)	NC score	0.126259 (rank : 73)
Query Neighborhood Hits	153	Target Neighborhood Hits	347	Shared Neighborhood Hits	62
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

NOTC4_HUMAN
θ value	0.365318 (rank : 82)	NC score	0.107301 (rank : 100)
Query Neighborhood Hits	153	Target Neighborhood Hits	905	Shared Neighborhood Hits	84
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

NOTC4_MOUSE
θ value	0.365318 (rank : 83)	NC score	0.105342 (rank : 106)
Query Neighborhood Hits	153	Target Neighborhood Hits	872	Shared Neighborhood Hits	84
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

PCSK5_HUMAN
θ value	0.365318 (rank : 84)	NC score	0.052932 (rank : 321)
Query Neighborhood Hits	153	Target Neighborhood Hits	291	Shared Neighborhood Hits	51
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).

STAB2_MOUSE
θ value	0.365318 (rank : 85)	NC score	0.090213 (rank : 133)
Query Neighborhood Hits	153	Target Neighborhood Hits	528	Shared Neighborhood Hits	71
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

KR102_HUMAN
θ value	0.47712 (rank : 86)	NC score	0.131214 (rank : 68)
Query Neighborhood Hits	153	Target Neighborhood Hits	264	Shared Neighborhood Hits	54
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

LAMC3_MOUSE
θ value	0.47712 (rank : 87)	NC score	0.071617 (rank : 211)
Query Neighborhood Hits	153	Target Neighborhood Hits	624	Shared Neighborhood Hits	68
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LTB1L_HUMAN
θ value	0.47712 (rank : 88)	NC score	0.093268 (rank : 128)
Query Neighborhood Hits	153	Target Neighborhood Hits	553	Shared Neighborhood Hits	70
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_HUMAN
θ value	0.47712 (rank : 89)	NC score	0.092924 (rank : 130)
Query Neighborhood Hits	153	Target Neighborhood Hits	502	Shared Neighborhood Hits	67
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

TNR14_HUMAN
θ value	0.47712 (rank : 90)	NC score	0.078879 (rank : 172)
Query Neighborhood Hits	153	Target Neighborhood Hits	149	Shared Neighborhood Hits	30
SwissProt Accessions	Q92956, Q8WXR1, Q96J31, Q9UM65	Gene names	TNFRSF14, HVEA, HVEM
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 14 precursor (Herpesvirus entry mediator A) (Tumor necrosis factor receptor-like 2) (TR2).

TSP2_HUMAN
θ value	0.47712 (rank : 91)	NC score	0.047980 (rank : 344)
Query Neighborhood Hits	153	Target Neighborhood Hits	359	Shared Neighborhood Hits	58
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

FBN1_HUMAN
θ value	0.62314 (rank : 92)	NC score	0.107028 (rank : 101)
Query Neighborhood Hits	153	Target Neighborhood Hits	557	Shared Neighborhood Hits	79
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

KR104_HUMAN
θ value	0.62314 (rank : 93)	NC score	0.142246 (rank : 60)
Query Neighborhood Hits	153	Target Neighborhood Hits	313	Shared Neighborhood Hits	60
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

VAV_MOUSE
θ value	0.62314 (rank : 94)	NC score	0.010508 (rank : 364)
Query Neighborhood Hits	153	Target Neighborhood Hits	430	Shared Neighborhood Hits	3
SwissProt Accessions	P27870, Q8BTV7	Gene names	Vav1, Vav
Domain Architecture
Description	Proto-oncogene vav (p95vav).

CCNT2_HUMAN
θ value	0.813845 (rank : 95)	NC score	0.040676 (rank : 345)
Query Neighborhood Hits	153	Target Neighborhood Hits	84	Shared Neighborhood Hits	5
SwissProt Accessions	O60583, O60582, Q5I1Y0	Gene names	CCNT2
Domain Architecture
Description	Cyclin-T2 (CycT2).

GOPC_HUMAN
θ value	0.813845 (rank : 96)	NC score	0.023452 (rank : 355)
Query Neighborhood Hits	153	Target Neighborhood Hits	377	Shared Neighborhood Hits	4
SwissProt Accessions	Q9HD26, Q59FS4, Q969U8	Gene names	GOPC, CAL, FIG
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST) (CFTR-associated ligand) (Fused in glioblastoma).

GOPC_MOUSE
θ value	0.813845 (rank : 97)	NC score	0.024043 (rank : 354)
Query Neighborhood Hits	153	Target Neighborhood Hits	323	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BH60, Q8BSV4, Q920R1, Q9ET11	Gene names	Gopc
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST).

NOTC2_HUMAN
θ value	0.813845 (rank : 98)	NC score	0.108973 (rank : 92)
Query Neighborhood Hits	153	Target Neighborhood Hits	1113	Shared Neighborhood Hits	84
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

FBLN2_MOUSE
θ value	1.06291 (rank : 99)	NC score	0.097022 (rank : 119)
Query Neighborhood Hits	153	Target Neighborhood Hits	505	Shared Neighborhood Hits	77
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

FBN1_MOUSE
θ value	1.06291 (rank : 100)	NC score	0.106738 (rank : 103)
Query Neighborhood Hits	153	Target Neighborhood Hits	563	Shared Neighborhood Hits	78
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

VWF_HUMAN
θ value	1.06291 (rank : 101)	NC score	0.058985 (rank : 278)
Query Neighborhood Hits	153	Target Neighborhood Hits	396	Shared Neighborhood Hits	57
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

FBLN1_HUMAN
θ value	1.38821 (rank : 102)	NC score	0.093982 (rank : 127)
Query Neighborhood Hits	153	Target Neighborhood Hits	324	Shared Neighborhood Hits	60
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

FBLN2_HUMAN
θ value	1.38821 (rank : 103)	NC score	0.097264 (rank : 118)
Query Neighborhood Hits	153	Target Neighborhood Hits	392	Shared Neighborhood Hits	67
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

KR108_HUMAN
θ value	1.38821 (rank : 104)	NC score	0.112226 (rank : 89)
Query Neighborhood Hits	153	Target Neighborhood Hits	226	Shared Neighborhood Hits	52
SwissProt Accessions	P60410	Gene names	KRTAP10-8, KAP10.8, KAP18-8, KRTAP10.8, KRTAP18-8, KRTAP18.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-8 (Keratin-associated protein 10.8) (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8).

LAMA5_HUMAN
θ value	1.38821 (rank : 105)	NC score	0.082008 (rank : 156)
Query Neighborhood Hits	153	Target Neighborhood Hits	976	Shared Neighborhood Hits	73
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

ADA33_MOUSE
θ value	1.81305 (rank : 106)	NC score	0.022763 (rank : 357)
Query Neighborhood Hits	153	Target Neighborhood Hits	231	Shared Neighborhood Hits	37
SwissProt Accessions	Q923W9	Gene names	Adam33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

NOTC2_MOUSE
θ value	1.81305 (rank : 107)	NC score	0.107731 (rank : 96)
Query Neighborhood Hits	153	Target Neighborhood Hits	1069	Shared Neighborhood Hits	82
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

REXO1_MOUSE
θ value	1.81305 (rank : 108)	NC score	0.025083 (rank : 352)
Query Neighborhood Hits	153	Target Neighborhood Hits	166	Shared Neighborhood Hits	4
SwissProt Accessions	Q7TT28, Q3UMP1, Q69ZR0, Q6NSQ6, Q6PI95, Q9DA29	Gene names	Rexo1, Kiaa1138, Tceb3bp1
Domain Architecture	No domain graphic available
Description	RNA exonuclease 1 homolog (EC 3.1.-.-) (Transcription elongation factor B polypeptide 3-binding protein 1).

CSPG3_MOUSE
θ value	2.36792 (rank : 109)	NC score	0.114470 (rank : 86)
Query Neighborhood Hits	153	Target Neighborhood Hits	657	Shared Neighborhood Hits	86
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

JAG1_MOUSE
θ value	2.36792 (rank : 110)	NC score	0.104101 (rank : 109)
Query Neighborhood Hits	153	Target Neighborhood Hits	518	Shared Neighborhood Hits	79
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

LTBP2_MOUSE
θ value	2.36792 (rank : 111)	NC score	0.109642 (rank : 91)
Query Neighborhood Hits	153	Target Neighborhood Hits	617	Shared Neighborhood Hits	76
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

PCSK5_MOUSE
θ value	2.36792 (rank : 112)	NC score	0.096105 (rank : 121)
Query Neighborhood Hits	153	Target Neighborhood Hits	613	Shared Neighborhood Hits	79
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

ATS9_HUMAN
θ value	3.0926 (rank : 113)	NC score	0.018777 (rank : 360)
Query Neighborhood Hits	153	Target Neighborhood Hits	219	Shared Neighborhood Hits	32
SwissProt Accessions	Q9P2N4, Q9NR29	Gene names	ADAMTS9, KIAA1312
Domain Architecture
Description	ADAMTS-9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 9) (ADAM-TS 9) (ADAM-TS9).

CCNT1_HUMAN
θ value	3.0926 (rank : 114)	NC score	0.030738 (rank : 348)
Query Neighborhood Hits	153	Target Neighborhood Hits	46	Shared Neighborhood Hits	5
SwissProt Accessions	O60563, O60581	Gene names	CCNT1
Domain Architecture
Description	Cyclin-T1 (CycT1) (Cyclin-T).

CCNT1_MOUSE
θ value	3.0926 (rank : 115)	NC score	0.030700 (rank : 349)
Query Neighborhood Hits	153	Target Neighborhood Hits	58	Shared Neighborhood Hits	5
SwissProt Accessions	Q9QWV9, Q9Z0U7	Gene names	Ccnt1
Domain Architecture
Description	Cyclin-T1 (CycT1) (Cyclin-T).

KR10A_HUMAN
θ value	3.0926 (rank : 116)	NC score	0.094929 (rank : 124)
Query Neighborhood Hits	153	Target Neighborhood Hits	232	Shared Neighborhood Hits	47
SwissProt Accessions	P60014	Gene names	KRTAP10-10, KAP10.10, KAP18-10, KRTAP10.10, KRTAP18-1, KRTAP18.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-10 (Keratin-associated protein 10.10) (High sulfur keratin-associated protein 10.10) (Keratin-associated protein 18-10) (Keratin-associated protein 18.10).

KR10C_HUMAN
θ value	3.0926 (rank : 117)	NC score	0.107943 (rank : 95)
Query Neighborhood Hits	153	Target Neighborhood Hits	219	Shared Neighborhood Hits	50
SwissProt Accessions	P60413	Gene names	KRTAP10-12, KAP10.12, KAP18-12, KRTAP10.12, KRTAP18-12, KRTAP18.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-12 (Keratin-associated protein 10.12) (High sulfur keratin-associated protein 10.12) (Keratin-associated protein 18-12) (Keratin-associated protein 18.12).

BCL6B_HUMAN
θ value	4.03905 (rank : 118)	NC score	-0.002356 (rank : 380)
Query Neighborhood Hits	153	Target Neighborhood Hits	855	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N143, Q6PCB4	Gene names	BCL6B, BAZF, ZNF62
Domain Architecture	No domain graphic available
Description	B-cell CLL/lymphoma 6 member B protein (Bcl6-associated zinc finger protein) (Zinc finger protein 62).

CDKN3_HUMAN
θ value	4.03905 (rank : 119)	NC score	0.026744 (rank : 351)
Query Neighborhood Hits	153	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	Q16667, Q99585, Q9BPW7, Q9BY36, Q9C042, Q9C047, Q9C049, Q9C051, Q9C053	Gene names	CDKN3, CDI1, CIP2, KAP
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 3 (EC 3.1.3.48) (EC 3.1.3.16) (CDK2- associated dual-specificity phosphatase) (Kinase-associated phosphatase) (Cyclin-dependent kinase-interacting protein 2) (Cyclin- dependent kinase interactor 1).

JAG1_HUMAN
θ value	4.03905 (rank : 120)	NC score	0.104352 (rank : 108)
Query Neighborhood Hits	153	Target Neighborhood Hits	514	Shared Neighborhood Hits	81
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

KRA24_HUMAN
θ value	4.03905 (rank : 121)	NC score	0.058173 (rank : 290)
Query Neighborhood Hits	153	Target Neighborhood Hits	192	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BYR9, Q495J2	Gene names	KRTAP2-4, KAP2.4, KRTAP2.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 2-4 (Keratin-associated protein 2.4) (High sulfur keratin-associated protein 2.4).

LRP2_HUMAN
θ value	4.03905 (rank : 122)	NC score	0.066688 (rank : 232)
Query Neighborhood Hits	153	Target Neighborhood Hits	573	Shared Neighborhood Hits	74
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

LTBP3_MOUSE
θ value	4.03905 (rank : 123)	NC score	0.100145 (rank : 114)
Query Neighborhood Hits	153	Target Neighborhood Hits	475	Shared Neighborhood Hits	82
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

NAGPA_HUMAN
θ value	4.03905 (rank : 124)	NC score	0.079401 (rank : 169)
Query Neighborhood Hits	153	Target Neighborhood Hits	282	Shared Neighborhood Hits	54
SwissProt Accessions	Q9UK23, Q96EJ8	Gene names	NAGPA
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

PTN23_MOUSE
θ value	4.03905 (rank : 125)	NC score	0.006926 (rank : 372)
Query Neighborhood Hits	153	Target Neighborhood Hits	726	Shared Neighborhood Hits	10
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

RX_MOUSE
θ value	4.03905 (rank : 126)	NC score	0.007012 (rank : 371)
Query Neighborhood Hits	153	Target Neighborhood Hits	429	Shared Neighborhood Hits	3
SwissProt Accessions	O35602, O08748	Gene names	Rax, Rx
Domain Architecture
Description	Retinal homeobox protein Rx (Retina and anterior neural fold homeobox protein).

WISP1_MOUSE
θ value	4.03905 (rank : 127)	NC score	0.024547 (rank : 353)
Query Neighborhood Hits	153	Target Neighborhood Hits	123	Shared Neighborhood Hits	17
SwissProt Accessions	O54775, Q80ZL1	Gene names	Wisp1, Ccn4, Elm1
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (ELM-1).

ZN563_HUMAN
θ value	4.03905 (rank : 128)	NC score	-0.004234 (rank : 381)
Query Neighborhood Hits	153	Target Neighborhood Hits	754	Shared Neighborhood Hits	5
SwissProt Accessions	Q8TA94, Q8NAT7	Gene names	ZNF563
Domain Architecture	No domain graphic available
Description	Zinc finger protein 563.

ADA33_HUMAN
θ value	5.27518 (rank : 129)	NC score	0.023376 (rank : 356)
Query Neighborhood Hits	153	Target Neighborhood Hits	264	Shared Neighborhood Hits	45
SwissProt Accessions	Q9BZ11, Q5JT75, Q5JT76, Q8N0W6	Gene names	ADAM33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

AGRIN_HUMAN
θ value	5.27518 (rank : 130)	NC score	0.074920 (rank : 194)
Query Neighborhood Hits	153	Target Neighborhood Hits	582	Shared Neighborhood Hits	71
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

KR101_HUMAN
θ value	5.27518 (rank : 131)	NC score	0.127169 (rank : 72)
Query Neighborhood Hits	153	Target Neighborhood Hits	261	Shared Neighborhood Hits	52
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

MEGF8_MOUSE
θ value	5.27518 (rank : 132)	NC score	0.072937 (rank : 205)
Query Neighborhood Hits	153	Target Neighborhood Hits	520	Shared Neighborhood Hits	61
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

VAV_HUMAN
θ value	5.27518 (rank : 133)	NC score	0.006759 (rank : 373)
Query Neighborhood Hits	153	Target Neighborhood Hits	452	Shared Neighborhood Hits	3
SwissProt Accessions	P15498, Q15860	Gene names	VAV1, VAV
Domain Architecture
Description	Proto-oncogene vav.

WDFY1_HUMAN
θ value	5.27518 (rank : 134)	NC score	0.004539 (rank : 377)
Query Neighborhood Hits	153	Target Neighborhood Hits	305	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IWB7, Q9H9D5, Q9P2B3	Gene names	WDFY1, KIAA1435, WDF1, ZFYVE17
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 1 (WD40- and FYVE domain- containing protein 1) (Phosphoinositide-binding protein 1) (FENS-1) (Zinc finger FYVE domain-containing protein 17).

YTDC1_HUMAN
θ value	5.27518 (rank : 135)	NC score	0.007549 (rank : 368)
Query Neighborhood Hits	153	Target Neighborhood Hits	458	Shared Neighborhood Hits	2
SwissProt Accessions	Q96MU7, Q7Z622, Q8TF35	Gene names	YTHDC1, KIAA1966, YT521
Domain Architecture
Description	YTH domain-containing protein 1 (Putative splicing factor YT521).

CSPG3_HUMAN
θ value	6.88961 (rank : 136)	NC score	0.108660 (rank : 93)
Query Neighborhood Hits	153	Target Neighborhood Hits	676	Shared Neighborhood Hits	86
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

MMP21_HUMAN
θ value	6.88961 (rank : 137)	NC score	0.009861 (rank : 365)
Query Neighborhood Hits	153	Target Neighborhood Hits	76	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N119, Q8NG02	Gene names	MMP21
Domain Architecture	No domain graphic available
Description	Matrix metalloproteinase-21 precursor (EC 3.4.24.-) (MMP-21).

PTN21_MOUSE
θ value	6.88961 (rank : 138)	NC score	0.004708 (rank : 376)
Query Neighborhood Hits	153	Target Neighborhood Hits	155	Shared Neighborhood Hits	4
SwissProt Accessions	Q62136	Gene names	Ptpn21
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-RL10).

SEM3F_MOUSE
θ value	6.88961 (rank : 139)	NC score	0.002227 (rank : 378)
Query Neighborhood Hits	153	Target Neighborhood Hits	86	Shared Neighborhood Hits	2
SwissProt Accessions	O88632, O88633	Gene names	Sema3f
Domain Architecture
Description	Semaphorin-3F precursor (Semaphorin IV) (Sema IV).

ADA21_HUMAN
θ value	8.99809 (rank : 140)	NC score	0.014713 (rank : 362)
Query Neighborhood Hits	153	Target Neighborhood Hits	181	Shared Neighborhood Hits	37
SwissProt Accessions	Q9UKJ8, O43507	Gene names	ADAM21
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21).

ANM7_HUMAN
θ value	8.99809 (rank : 141)	NC score	0.007917 (rank : 367)
Query Neighborhood Hits	153	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NVM4, Q96PV5, Q9H9L0	Gene names	PRMT7, KIAA1933
Domain Architecture
Description	Protein arginine N-methyltransferase 7 (EC 2.1.1.-).

CAD13_MOUSE
θ value	8.99809 (rank : 142)	NC score	-0.000443 (rank : 379)
Query Neighborhood Hits	153	Target Neighborhood Hits	156	Shared Neighborhood Hits	2
SwissProt Accessions	Q9WTR5	Gene names	Cdh13
Domain Architecture
Description	Cadherin-13 precursor (Truncated-cadherin) (T-cadherin) (T-cad) (Heart-cadherin) (H-cadherin).

CDAN1_HUMAN
θ value	8.99809 (rank : 143)	NC score	0.011535 (rank : 363)
Query Neighborhood Hits	153	Target Neighborhood Hits	92	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IWY9, Q7Z7L5, Q969N3	Gene names	CDAN1
Domain Architecture	No domain graphic available
Description	Codanin-1.

FBN2_MOUSE
θ value	8.99809 (rank : 144)	NC score	0.104737 (rank : 107)
Query Neighborhood Hits	153	Target Neighborhood Hits	549	Shared Neighborhood Hits	81
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

GPX5_MOUSE
θ value	8.99809 (rank : 145)	NC score	0.005135 (rank : 374)
Query Neighborhood Hits	153	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	P21765	Gene names	Gpx5
Domain Architecture
Description	Epididymal secretory glutathione peroxidase precursor (EC 1.11.1.9) (Epididymis-specific glutathione peroxidase-like protein) (EGLP) (Major androgen-regulated protein) (arMEP24).

LAMB2_HUMAN
θ value	8.99809 (rank : 146)	NC score	0.063243 (rank : 246)
Query Neighborhood Hits	153	Target Neighborhood Hits	692	Shared Neighborhood Hits	62
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

MEGF8_HUMAN
θ value	8.99809 (rank : 147)	NC score	0.074821 (rank : 196)
Query Neighborhood Hits	153	Target Neighborhood Hits	528	Shared Neighborhood Hits	67
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

MMP21_MOUSE
θ value	8.99809 (rank : 148)	NC score	0.008951 (rank : 366)
Query Neighborhood Hits	153	Target Neighborhood Hits	59	Shared Neighborhood Hits	6
SwissProt Accessions	Q8K3F2	Gene names	Mmp21
Domain Architecture	No domain graphic available
Description	Matrix metalloproteinase-21 precursor (EC 3.4.24.-) (MMP-21).

OFD1_HUMAN
θ value	8.99809 (rank : 149)	NC score	0.005022 (rank : 375)
Query Neighborhood Hits	153	Target Neighborhood Hits	753	Shared Neighborhood Hits	4
SwissProt Accessions	O75665, O75666	Gene names	OFD1, CXorf5
Domain Architecture	No domain graphic available
Description	Oral-facial-digital syndrome 1 protein (Protein 71-7A).

POMT2_MOUSE
θ value	8.99809 (rank : 150)	NC score	0.007134 (rank : 370)
Query Neighborhood Hits	153	Target Neighborhood Hits	26	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BGQ4, Q8R4Z0	Gene names	Pomt2
Domain Architecture
Description	Protein O-mannosyl-transferase 2 (EC 2.4.1.109) (Dolichyl-phosphate- mannose--protein mannosyltransferase 2).

PSPB_HUMAN
θ value	8.99809 (rank : 151)	NC score	0.028844 (rank : 350)
Query Neighborhood Hits	153	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	P07988, Q96R04	Gene names	SFTPB, SFTP3
Domain Architecture
Description	Pulmonary surfactant-associated protein B precursor (SP-B) (6 kDa protein) (Pulmonary surfactant-associated proteolipid SPL(Phe)) (18 kDa pulmonary-surfactant protein).

WDR4_HUMAN
θ value	8.99809 (rank : 152)	NC score	0.007210 (rank : 369)
Query Neighborhood Hits	153	Target Neighborhood Hits	145	Shared Neighborhood Hits	2
SwissProt Accessions	P57081, Q9HCR3	Gene names	WDR4
Domain Architecture
Description	WD repeat protein 4.

WISP1_HUMAN
θ value	8.99809 (rank : 153)	NC score	0.021264 (rank : 358)
Query Neighborhood Hits	153	Target Neighborhood Hits	121	Shared Neighborhood Hits	18
SwissProt Accessions	O95388, Q9HCS3	Gene names	WISP1, CCN4
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (Wnt-1- induced secreted protein).

ATRN_HUMAN
θ value	θ > 10 (rank : 154)	NC score	0.088953 (rank : 134)
Query Neighborhood Hits	153	Target Neighborhood Hits	525	Shared Neighborhood Hits	62
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

ATRN_MOUSE
θ value	θ > 10 (rank : 155)	NC score	0.086779 (rank : 142)
Query Neighborhood Hits	153	Target Neighborhood Hits	519	Shared Neighborhood Hits	63
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

BMP1_HUMAN
θ value	θ > 10 (rank : 156)	NC score	0.106901 (rank : 102)
Query Neighborhood Hits	153	Target Neighborhood Hits	233	Shared Neighborhood Hits	47
SwissProt Accessions	P13497, Q13292, Q13872, Q14874, Q99421, Q99422, Q99423, Q9UL38	Gene names	BMP1, PCOLC
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

BMP1_MOUSE
θ value	θ > 10 (rank : 157)	NC score	0.107335 (rank : 98)
Query Neighborhood Hits	153	Target Neighborhood Hits	236	Shared Neighborhood Hits	47
SwissProt Accessions	P98063	Gene names	Bmp1
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

C1QR1_HUMAN
θ value	θ > 10 (rank : 158)	NC score	0.083937 (rank : 153)
Query Neighborhood Hits	153	Target Neighborhood Hits	493	Shared Neighborhood Hits	70
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

C1QR1_MOUSE
θ value	θ > 10 (rank : 159)	NC score	0.091039 (rank : 132)
Query Neighborhood Hits	153	Target Neighborhood Hits	342	Shared Neighborhood Hits	64
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

C1RA_MOUSE
θ value	θ > 10 (rank : 160)	NC score	0.118974 (rank : 81)
Query Neighborhood Hits	153	Target Neighborhood Hits	379	Shared Neighborhood Hits	72
SwissProt Accessions	Q8CG16, Q99KI6, Q9ET60	Gene names	C1ra, C1r
Domain Architecture
Description	Complement C1r-A subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-A subcomponent) [Contains: Complement C1r-A subcomponent heavy chain; Complement C1r-A subcomponent light chain].

C1RB_MOUSE
θ value	θ > 10 (rank : 161)	NC score	0.118384 (rank : 82)
Query Neighborhood Hits	153	Target Neighborhood Hits	380	Shared Neighborhood Hits	72
SwissProt Accessions	Q8CFG9	Gene names	C1rb, C1r
Domain Architecture	No domain graphic available
Description	Complement C1r-B subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-B subcomponent) [Contains: Complement C1r-B subcomponent heavy chain; Complement C1r-B subcomponent light chain].

C1R_HUMAN
θ value	θ > 10 (rank : 162)	NC score	0.120918 (rank : 80)
Query Neighborhood Hits	153	Target Neighborhood Hits	364	Shared Neighborhood Hits	73
SwissProt Accessions	P00736, Q8J012	Gene names	C1R
Domain Architecture
Description	Complement C1r subcomponent precursor (EC 3.4.21.41) (Complement component 1, r subcomponent) [Contains: Complement C1r subcomponent heavy chain; Complement C1r subcomponent light chain].

CD248_HUMAN
θ value	θ > 10 (rank : 163)	NC score	0.055853 (rank : 303)
Query Neighborhood Hits	153	Target Neighborhood Hits	679	Shared Neighborhood Hits	60
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CD248_MOUSE
θ value	θ > 10 (rank : 164)	NC score	0.059796 (rank : 270)
Query Neighborhood Hits	153	Target Neighborhood Hits	578	Shared Neighborhood Hits	57
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CD97_HUMAN
θ value	θ > 10 (rank : 165)	NC score	0.067931 (rank : 227)
Query Neighborhood Hits	153	Target Neighborhood Hits	353	Shared Neighborhood Hits	62
SwissProt Accessions	P48960, O00718, O76101, Q8NG72, Q8TBQ7	Gene names	CD97
Domain Architecture
Description	CD97 antigen precursor (Leukocyte antigen CD97).

CO7_HUMAN
θ value	θ > 10 (rank : 166)	NC score	0.206273 (rank : 50)
Query Neighborhood Hits	153	Target Neighborhood Hits	278	Shared Neighborhood Hits	74
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

COMP_HUMAN
θ value	θ > 10 (rank : 167)	NC score	0.051155 (rank : 335)
Query Neighborhood Hits	153	Target Neighborhood Hits	258	Shared Neighborhood Hits	46
SwissProt Accessions	P49747, O14592, Q16388, Q16389, Q8N4T2	Gene names	COMP
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

COMP_MOUSE
θ value	θ > 10 (rank : 168)	NC score	0.053272 (rank : 315)
Query Neighborhood Hits	153	Target Neighborhood Hits	290	Shared Neighborhood Hits	47
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

CREL1_HUMAN
θ value	θ > 10 (rank : 169)	NC score	0.063453 (rank : 245)
Query Neighborhood Hits	153	Target Neighborhood Hits	441	Shared Neighborhood Hits	50
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

CREL1_MOUSE
θ value	θ > 10 (rank : 170)	NC score	0.063216 (rank : 247)
Query Neighborhood Hits	153	Target Neighborhood Hits	524	Shared Neighborhood Hits	50
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

CRIM1_HUMAN
θ value	θ > 10 (rank : 171)	NC score	0.066953 (rank : 230)
Query Neighborhood Hits	153	Target Neighborhood Hits	362	Shared Neighborhood Hits	58
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

CRUM1_HUMAN
θ value	θ > 10 (rank : 172)	NC score	0.087334 (rank : 139)
Query Neighborhood Hits	153	Target Neighborhood Hits	457	Shared Neighborhood Hits	69
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

CRUM1_MOUSE
θ value	θ > 10 (rank : 173)	NC score	0.084689 (rank : 150)
Query Neighborhood Hits	153	Target Neighborhood Hits	444	Shared Neighborhood Hits	69
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

CRUM2_HUMAN
θ value	θ > 10 (rank : 174)	NC score	0.088381 (rank : 136)
Query Neighborhood Hits	153	Target Neighborhood Hits	453	Shared Neighborhood Hits	74
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

CSPG2_HUMAN
θ value	θ > 10 (rank : 175)	NC score	0.095636 (rank : 123)
Query Neighborhood Hits	153	Target Neighborhood Hits	681	Shared Neighborhood Hits	81
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

CSPG2_MOUSE
θ value	θ > 10 (rank : 176)	NC score	0.095791 (rank : 122)
Query Neighborhood Hits	153	Target Neighborhood Hits	711	Shared Neighborhood Hits	81
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

CUBN_HUMAN
θ value	θ > 10 (rank : 177)	NC score	0.136388 (rank : 65)
Query Neighborhood Hits	153	Target Neighborhood Hits	482	Shared Neighborhood Hits	70
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

CUBN_MOUSE
θ value	θ > 10 (rank : 178)	NC score	0.129268 (rank : 70)
Query Neighborhood Hits	153	Target Neighborhood Hits	477	Shared Neighborhood Hits	72
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

CUZD1_HUMAN
θ value	θ > 10 (rank : 179)	NC score	0.072180 (rank : 209)
Query Neighborhood Hits	153	Target Neighborhood Hits	89	Shared Neighborhood Hits	12
SwissProt Accessions	Q86UP6, Q7Z660, Q7Z661, Q86SG1, Q86UP5, Q9HAR7	Gene names	CUZD1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Transmembrane protein UO-44).

CUZD1_MOUSE
θ value	θ > 10 (rank : 180)	NC score	0.067340 (rank : 229)
Query Neighborhood Hits	153	Target Neighborhood Hits	91	Shared Neighborhood Hits	12
SwissProt Accessions	P70412, Q9CTZ7	Gene names	Cuzd1, Itmap1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Integral membrane-associated protein 1).

DCBD1_MOUSE
θ value	θ > 10 (rank : 181)	NC score	0.064400 (rank : 241)
Query Neighborhood Hits	153	Target Neighborhood Hits	89	Shared Neighborhood Hits	12
SwissProt Accessions	Q9D4J3, Q8R327, Q9D696	Gene names	Dcbld1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

DCBD2_HUMAN
θ value	θ > 10 (rank : 182)	NC score	0.052095 (rank : 326)
Query Neighborhood Hits	153	Target Neighborhood Hits	118	Shared Neighborhood Hits	13
SwissProt Accessions	Q96PD2, Q8N6M4, Q8TDX2	Gene names	DCBLD2, CLCP1, ESDN
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein) (CUB, LCCL and coagulation factor V/VIII-homology domains protein 1).

DLK_HUMAN
θ value	θ > 10 (rank : 183)	NC score	0.084549 (rank : 152)
Query Neighborhood Hits	153	Target Neighborhood Hits	401	Shared Neighborhood Hits	69
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

DLK_MOUSE
θ value	θ > 10 (rank : 184)	NC score	0.083677 (rank : 154)
Query Neighborhood Hits	153	Target Neighborhood Hits	374	Shared Neighborhood Hits	62
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

DLL3_HUMAN
θ value	θ > 10 (rank : 185)	NC score	0.085725 (rank : 146)
Query Neighborhood Hits	153	Target Neighborhood Hits	419	Shared Neighborhood Hits	67
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

DLL3_MOUSE
θ value	θ > 10 (rank : 186)	NC score	0.081858 (rank : 158)
Query Neighborhood Hits	153	Target Neighborhood Hits	399	Shared Neighborhood Hits	62
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

DLL4_HUMAN
θ value	θ > 10 (rank : 187)	NC score	0.085400 (rank : 148)
Query Neighborhood Hits	153	Target Neighborhood Hits	435	Shared Neighborhood Hits	69
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

DLL4_MOUSE
θ value	θ > 10 (rank : 188)	NC score	0.086686 (rank : 143)
Query Neighborhood Hits	153	Target Neighborhood Hits	440	Shared Neighborhood Hits	67
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

DMBT1_HUMAN
θ value	θ > 10 (rank : 189)	NC score	0.051491 (rank : 333)
Query Neighborhood Hits	153	Target Neighborhood Hits	152	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UGM3, Q59EX0, Q5JR26, Q6MZN4, Q96DU4, Q9UGM2, Q9UJ57, Q9UKJ4, Q9Y211, Q9Y4V9	Gene names	DMBT1, GP340
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (Glycoprotein 340) (Gp-340) (Surfactant pulmonary-associated D-binding protein).

DMBT1_MOUSE
θ value	θ > 10 (rank : 190)	NC score	0.062398 (rank : 251)
Query Neighborhood Hits	153	Target Neighborhood Hits	134	Shared Neighborhood Hits	12
SwissProt Accessions	Q60997, Q80YC6, Q9JMJ9	Gene names	Dmbt1, Crpd
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (CRP-ductin) (Vomeroglandin).

DNER_HUMAN
θ value	θ > 10 (rank : 191)	NC score	0.088840 (rank : 135)
Query Neighborhood Hits	153	Target Neighborhood Hits	460	Shared Neighborhood Hits	67
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

DNER_MOUSE
θ value	θ > 10 (rank : 192)	NC score	0.087284 (rank : 140)
Query Neighborhood Hits	153	Target Neighborhood Hits	413	Shared Neighborhood Hits	67
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

EDIL3_HUMAN
θ value	θ > 10 (rank : 193)	NC score	0.058009 (rank : 291)
Query Neighborhood Hits	153	Target Neighborhood Hits	292	Shared Neighborhood Hits	55
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

EDIL3_MOUSE
θ value	θ > 10 (rank : 194)	NC score	0.058910 (rank : 280)
Query Neighborhood Hits	153	Target Neighborhood Hits	317	Shared Neighborhood Hits	55
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

EGFL7_HUMAN
θ value	θ > 10 (rank : 195)	NC score	0.062896 (rank : 249)
Query Neighborhood Hits	153	Target Neighborhood Hits	325	Shared Neighborhood Hits	54
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

EGFL7_MOUSE
θ value	θ > 10 (rank : 196)	NC score	0.062141 (rank : 256)
Query Neighborhood Hits	153	Target Neighborhood Hits	287	Shared Neighborhood Hits	50
SwissProt Accessions	Q9QXT5, Q6XD35, Q9DCP5	Gene names	Egfl7, Megf7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (Zneu1).

EGFL8_HUMAN
θ value	θ > 10 (rank : 197)	NC score	0.065862 (rank : 234)
Query Neighborhood Hits	153	Target Neighborhood Hits	270	Shared Neighborhood Hits	47
SwissProt Accessions	Q99944, Q8IV30	Gene names	EGFL8, C6orf8, NG3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8) (Vascular endothelial-statin 2) (VE-statin-2).

EGFL8_MOUSE
θ value	θ > 10 (rank : 198)	NC score	0.069890 (rank : 218)
Query Neighborhood Hits	153	Target Neighborhood Hits	266	Shared Neighborhood Hits	48
SwissProt Accessions	Q6GUQ1, O35447	Gene names	Egfl8, Ng3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8).

EGFL9_HUMAN
θ value	θ > 10 (rank : 199)	NC score	0.081993 (rank : 157)
Query Neighborhood Hits	153	Target Neighborhood Hits	365	Shared Neighborhood Hits	63
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

EGFL9_MOUSE
θ value	θ > 10 (rank : 200)	NC score	0.080768 (rank : 159)
Query Neighborhood Hits	153	Target Neighborhood Hits	379	Shared Neighborhood Hits	63
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

EGF_HUMAN
θ value	θ > 10 (rank : 201)	NC score	0.058933 (rank : 279)
Query Neighborhood Hits	153	Target Neighborhood Hits	343	Shared Neighborhood Hits	58
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

EGF_MOUSE
θ value	θ > 10 (rank : 202)	NC score	0.062381 (rank : 252)
Query Neighborhood Hits	153	Target Neighborhood Hits	358	Shared Neighborhood Hits	60
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

EMR1_HUMAN
θ value	θ > 10 (rank : 203)	NC score	0.070419 (rank : 216)
Query Neighborhood Hits	153	Target Neighborhood Hits	382	Shared Neighborhood Hits	63
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

EMR1_MOUSE
θ value	θ > 10 (rank : 204)	NC score	0.065500 (rank : 236)
Query Neighborhood Hits	153	Target Neighborhood Hits	349	Shared Neighborhood Hits	58
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

EMR2_HUMAN
θ value	θ > 10 (rank : 205)	NC score	0.069025 (rank : 222)
Query Neighborhood Hits	153	Target Neighborhood Hits	345	Shared Neighborhood Hits	62
SwissProt Accessions	Q9UHX3, Q8NG96, Q9Y4B1	Gene names	EMR2
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen).

FA10_HUMAN
θ value	θ > 10 (rank : 206)	NC score	0.058661 (rank : 282)
Query Neighborhood Hits	153	Target Neighborhood Hits	431	Shared Neighborhood Hits	56
SwissProt Accessions	P00742, Q14340	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) (Stuart- Prower factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

FA10_MOUSE
θ value	θ > 10 (rank : 207)	NC score	0.058222 (rank : 289)
Query Neighborhood Hits	153	Target Neighborhood Hits	435	Shared Neighborhood Hits	60
SwissProt Accessions	O88947, O54740, Q99L32	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

FA9_HUMAN
θ value	θ > 10 (rank : 208)	NC score	0.053112 (rank : 318)
Query Neighborhood Hits	153	Target Neighborhood Hits	421	Shared Neighborhood Hits	55
SwissProt Accessions	P00740	Gene names	F9
Domain Architecture
Description	Coagulation factor IX precursor (EC 3.4.21.22) (Christmas factor) (Plasma thromboplastin component) (PTC) [Contains: Coagulation factor IXa light chain; Coagulation factor IXa heavy chain].

FBLN3_HUMAN
θ value	θ > 10 (rank : 209)	NC score	0.077023 (rank : 181)
Query Neighborhood Hits	153	Target Neighborhood Hits	293	Shared Neighborhood Hits	56
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

FBLN3_MOUSE
θ value	θ > 10 (rank : 210)	NC score	0.077116 (rank : 179)
Query Neighborhood Hits	153	Target Neighborhood Hits	279	Shared Neighborhood Hits	57
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

FBLN4_HUMAN
θ value	θ > 10 (rank : 211)	NC score	0.079750 (rank : 166)
Query Neighborhood Hits	153	Target Neighborhood Hits	278	Shared Neighborhood Hits	58
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

FBLN4_MOUSE
θ value	θ > 10 (rank : 212)	NC score	0.078611 (rank : 176)
Query Neighborhood Hits	153	Target Neighborhood Hits	270	Shared Neighborhood Hits	55
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

FBLN5_HUMAN
θ value	θ > 10 (rank : 213)	NC score	0.079931 (rank : 164)
Query Neighborhood Hits	153	Target Neighborhood Hits	329	Shared Neighborhood Hits	65
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

FBLN5_MOUSE
θ value	θ > 10 (rank : 214)	NC score	0.085914 (rank : 145)
Query Neighborhood Hits	153	Target Neighborhood Hits	317	Shared Neighborhood Hits	64
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

FBN2_HUMAN
θ value	θ > 10 (rank : 215)	NC score	0.102480 (rank : 110)
Query Neighborhood Hits	153	Target Neighborhood Hits	560	Shared Neighborhood Hits	77
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN3_HUMAN
θ value	θ > 10 (rank : 216)	NC score	0.100913 (rank : 112)
Query Neighborhood Hits	153	Target Neighborhood Hits	543	Shared Neighborhood Hits	76
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

FRAS1_HUMAN
θ value	θ > 10 (rank : 217)	NC score	0.074970 (rank : 192)
Query Neighborhood Hits	153	Target Neighborhood Hits	759	Shared Neighborhood Hits	73
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

FRAS1_MOUSE
θ value	θ > 10 (rank : 218)	NC score	0.076621 (rank : 182)
Query Neighborhood Hits	153	Target Neighborhood Hits	747	Shared Neighborhood Hits	74
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

GABR1_HUMAN
θ value	θ > 10 (rank : 219)	NC score	0.149645 (rank : 56)
Query Neighborhood Hits	153	Target Neighborhood Hits	142	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UBS5, O95375, O95468, O95975, O96022, Q86W60, Q9UQQ0	Gene names	GABBR1, GPRC3A
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 1 precursor (GABA-B receptor 1) (GABA-B-R1) (Gb1).

GABR1_MOUSE
θ value	θ > 10 (rank : 220)	NC score	0.148732 (rank : 57)
Query Neighborhood Hits	153	Target Neighborhood Hits	139	Shared Neighborhood Hits	44
SwissProt Accessions	Q9WV18, Q9WU48, Q9WV15, Q9WV16, Q9WV17	Gene names	Gabbr1
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 1 precursor (GABA-B receptor 1) (GABA-B-R1) (Gb1).

GAS6_HUMAN
θ value	θ > 10 (rank : 221)	NC score	0.067993 (rank : 226)
Query Neighborhood Hits	153	Target Neighborhood Hits	348	Shared Neighborhood Hits	57
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

GAS6_MOUSE
θ value	θ > 10 (rank : 222)	NC score	0.064435 (rank : 240)
Query Neighborhood Hits	153	Target Neighborhood Hits	343	Shared Neighborhood Hits	60
SwissProt Accessions	Q61592, Q99K57	Gene names	Gas6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

GRN_HUMAN
θ value	θ > 10 (rank : 223)	NC score	0.079918 (rank : 165)
Query Neighborhood Hits	153	Target Neighborhood Hits	268	Shared Neighborhood Hits	57
SwissProt Accessions	P28799, P23781, P23782, P23783, P23784, Q9BWE7, Q9UCH0	Gene names	GRN
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)].

GRN_MOUSE
θ value	θ > 10 (rank : 224)	NC score	0.072064 (rank : 210)
Query Neighborhood Hits	153	Target Neighborhood Hits	248	Shared Neighborhood Hits	53
SwissProt Accessions	P28798	Gene names	Grn
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) (PC cell-derived growth factor) (PCDGF) [Contains: Acrogranin; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7].

HABP2_HUMAN
θ value	θ > 10 (rank : 225)	NC score	0.052699 (rank : 323)
Query Neighborhood Hits	153	Target Neighborhood Hits	431	Shared Neighborhood Hits	67
SwissProt Accessions	Q14520, O00663	Gene names	HABP2, HGFAL, PHBP
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) (Hepatocyte growth factor activator-like protein) (Factor VII-activating protease) (Factor seven-activating protease) (FSAP) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

HHIP_HUMAN
θ value	θ > 10 (rank : 226)	NC score	0.061313 (rank : 261)
Query Neighborhood Hits	153	Target Neighborhood Hits	249	Shared Neighborhood Hits	53
SwissProt Accessions	Q96QV1, Q6PK09, Q8NCI7, Q9BXK3, Q9H1J4, Q9H7E7	Gene names	HHIP, HIP
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

HHIP_MOUSE
θ value	θ > 10 (rank : 227)	NC score	0.054090 (rank : 312)
Query Neighborhood Hits	153	Target Neighborhood Hits	219	Shared Neighborhood Hits	43
SwissProt Accessions	Q7TN16, Q8C0B0, Q9WU59	Gene names	Hhip, Hip
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

HMCN1_HUMAN
θ value	θ > 10 (rank : 228)	NC score	0.053205 (rank : 316)
Query Neighborhood Hits	153	Target Neighborhood Hits	983	Shared Neighborhood Hits	75
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

HPT_HUMAN
θ value	θ > 10 (rank : 229)	NC score	0.056802 (rank : 298)
Query Neighborhood Hits	153	Target Neighborhood Hits	184	Shared Neighborhood Hits	29
SwissProt Accessions	P00738, P00737, Q2PP15, Q3B7J0, Q6LBY9	Gene names	HP
Domain Architecture
Description	Haptoglobin precursor [Contains: Haptoglobin alpha chain; Haptoglobin beta chain].

IL2RA_HUMAN
θ value	θ > 10 (rank : 230)	NC score	0.063608 (rank : 244)
Query Neighborhood Hits	153	Target Neighborhood Hits	32	Shared Neighborhood Hits	18
SwissProt Accessions	P01589	Gene names	IL2RA
Domain Architecture
Description	Interleukin-2 receptor alpha chain precursor (IL-2 receptor alpha subunit) (IL-2-RA) (IL2-RA) (p55) (TAC antigen) (CD25 antigen).

JAG2_HUMAN
θ value	θ > 10 (rank : 231)	NC score	0.093021 (rank : 129)
Query Neighborhood Hits	153	Target Neighborhood Hits	491	Shared Neighborhood Hits	76
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

JAG2_MOUSE
θ value	θ > 10 (rank : 232)	NC score	0.092665 (rank : 131)
Query Neighborhood Hits	153	Target Neighborhood Hits	504	Shared Neighborhood Hits	74
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

K0247_HUMAN
θ value	θ > 10 (rank : 233)	NC score	0.132486 (rank : 67)
Query Neighborhood Hits	153	Target Neighborhood Hits	42	Shared Neighborhood Hits	29
SwissProt Accessions	Q92537	Gene names	KIAA0247
Domain Architecture	No domain graphic available
Description	Protein KIAA0247 precursor.

KR103_HUMAN
θ value	θ > 10 (rank : 234)	NC score	0.086285 (rank : 144)
Query Neighborhood Hits	153	Target Neighborhood Hits	212	Shared Neighborhood Hits	42
SwissProt Accessions	P60369, Q70LJ4	Gene names	KRTAP10-3, KAP10.3, KAP18-3, KRTAP10.3, KRTAP18-3, KRTAP18.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-3 (Keratin-associated protein 10.3) (High sulfur keratin-associated protein 10.3) (Keratin-associated protein 18-3) (Keratin-associated protein 18.3).

KR105_HUMAN
θ value	θ > 10 (rank : 235)	NC score	0.098430 (rank : 116)
Query Neighborhood Hits	153	Target Neighborhood Hits	271	Shared Neighborhood Hits	49
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

KR171_HUMAN
θ value	θ > 10 (rank : 236)	NC score	0.063672 (rank : 243)
Query Neighborhood Hits	153	Target Neighborhood Hits	144	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BYP8	Gene names	KRTAP17-1, KAP17.1, KRTAP16.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 17-1 (Keratin-associated protein 16.1).

KR410_HUMAN
θ value	θ > 10 (rank : 237)	NC score	0.058416 (rank : 285)
Query Neighborhood Hits	153	Target Neighborhood Hits	156	Shared Neighborhood Hits	41
SwissProt Accessions	Q9BYQ7	Gene names	KRTAP4-10, KAP4.10, KRTAP4.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-10 (Keratin-associated protein 4.10) (Ultrahigh sulfur keratin-associated protein 4.10).

KR412_HUMAN
θ value	θ > 10 (rank : 238)	NC score	0.056704 (rank : 299)
Query Neighborhood Hits	153	Target Neighborhood Hits	178	Shared Neighborhood Hits	41
SwissProt Accessions	Q9BQ66, Q495I0	Gene names	KRTAP4-12, KAP4.12, KRTAP4.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12).

KR414_HUMAN
θ value	θ > 10 (rank : 239)	NC score	0.053173 (rank : 317)
Query Neighborhood Hits	153	Target Neighborhood Hits	199	Shared Neighborhood Hits	44
SwissProt Accessions	Q9BYQ6	Gene names	KRTAP4-14, KAP4.14, KRTAP4.14
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-14 (Keratin-associated protein 4.14) (Ultrahigh sulfur keratin-associated protein 4.14).

KR510_HUMAN
θ value	θ > 10 (rank : 240)	NC score	0.066613 (rank : 233)
Query Neighborhood Hits	153	Target Neighborhood Hits	217	Shared Neighborhood Hits	41
SwissProt Accessions	Q6L8G5	Gene names	KRTAP5-10, KAP5.10, KRTAP5.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-10 (Keratin-associated protein 5.10) (Ultrahigh sulfur keratin-associated protein 5.10).

KR511_HUMAN
θ value	θ > 10 (rank : 241)	NC score	0.073311 (rank : 202)
Query Neighborhood Hits	153	Target Neighborhood Hits	231	Shared Neighborhood Hits	44
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

KRA11_HUMAN
θ value	θ > 10 (rank : 242)	NC score	0.061206 (rank : 263)
Query Neighborhood Hits	153	Target Neighborhood Hits	155	Shared Neighborhood Hits	42
SwissProt Accessions	Q07627, Q96S60, Q96S67	Gene names	KRTAP1-1, B2A, KAP1.1, KAP1.6, KAP1.7, KRTAP1.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-1 (Keratin-associated protein 1.1) (High sulfur keratin-associated protein 1.1) (Keratin-associated protein 1.6) (Keratin-associated protein 1.7).

KRA13_HUMAN
θ value	θ > 10 (rank : 243)	NC score	0.074949 (rank : 193)
Query Neighborhood Hits	153	Target Neighborhood Hits	144	Shared Neighborhood Hits	43
SwissProt Accessions	Q8IUG1, Q07628, Q8IUG0, Q9BYS2	Gene names	KRTAP1-3, B2B, KAP1.2, KAP1.3, KAP1.8, KAP1.9, KRATP1.9, KRTAP1.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-3 (Keratin-associated protein 1.8) (Keratin-associated protein 1.9).

KRA15_HUMAN
θ value	θ > 10 (rank : 244)	NC score	0.055053 (rank : 307)
Query Neighborhood Hits	153	Target Neighborhood Hits	126	Shared Neighborhood Hits	34
SwissProt Accessions	Q9BYS1, Q52LP6	Gene names	KRTAP1-5, KAP1.5, KRTAP1.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-5 (Keratin-associated protein 1.5) (High sulfur keratin-associated protein 1.5).

KRA44_HUMAN
θ value	θ > 10 (rank : 245)	NC score	0.062253 (rank : 253)
Query Neighborhood Hits	153	Target Neighborhood Hits	162	Shared Neighborhood Hits	43
SwissProt Accessions	Q9BYR3	Gene names	KRTAP4-4, KAP4.4, KRTAP4.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-4 (Keratin-associated protein 4.4) (Ultrahigh sulfur keratin-associated protein 4.4).

KRA45_HUMAN
θ value	θ > 10 (rank : 246)	NC score	0.060397 (rank : 269)
Query Neighborhood Hits	153	Target Neighborhood Hits	194	Shared Neighborhood Hits	45
SwissProt Accessions	Q9BYR2	Gene names	KRTAP4-5, KAP4.5, KRTAP4.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-5 (Keratin-associated protein 4.5) (Ultrahigh sulfur keratin-associated protein 4.5).

KRA47_HUMAN
θ value	θ > 10 (rank : 247)	NC score	0.059365 (rank : 274)
Query Neighborhood Hits	153	Target Neighborhood Hits	204	Shared Neighborhood Hits	44
SwissProt Accessions	Q9BYR0	Gene names	KRTAP4-7, KAP4.7, KRTAP4.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-7 (Keratin-associated protein 4.7) (Ultrahigh sulfur keratin-associated protein 4.7).

KRA51_HUMAN
θ value	θ > 10 (rank : 248)	NC score	0.080741 (rank : 160)
Query Neighborhood Hits	153	Target Neighborhood Hits	288	Shared Neighborhood Hits	51
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

KRA52_HUMAN
θ value	θ > 10 (rank : 249)	NC score	0.071459 (rank : 212)
Query Neighborhood Hits	153	Target Neighborhood Hits	236	Shared Neighborhood Hits	45
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

KRA53_HUMAN
θ value	θ > 10 (rank : 250)	NC score	0.078702 (rank : 175)
Query Neighborhood Hits	153	Target Neighborhood Hits	331	Shared Neighborhood Hits	53
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

KRA54_HUMAN
θ value	θ > 10 (rank : 251)	NC score	0.074288 (rank : 197)
Query Neighborhood Hits	153	Target Neighborhood Hits	270	Shared Neighborhood Hits	47
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

KRA55_HUMAN
θ value	θ > 10 (rank : 252)	NC score	0.073006 (rank : 203)
Query Neighborhood Hits	153	Target Neighborhood Hits	257	Shared Neighborhood Hits	46
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

KRA56_HUMAN
θ value	θ > 10 (rank : 253)	NC score	0.062722 (rank : 250)
Query Neighborhood Hits	153	Target Neighborhood Hits	207	Shared Neighborhood Hits	41
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

KRA57_HUMAN
θ value	θ > 10 (rank : 254)	NC score	0.073630 (rank : 200)
Query Neighborhood Hits	153	Target Neighborhood Hits	269	Shared Neighborhood Hits	46
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

KRA58_HUMAN
θ value	θ > 10 (rank : 255)	NC score	0.072342 (rank : 208)
Query Neighborhood Hits	153	Target Neighborhood Hits	324	Shared Neighborhood Hits	49
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

KRA59_HUMAN
θ value	θ > 10 (rank : 256)	NC score	0.074882 (rank : 195)
Query Neighborhood Hits	153	Target Neighborhood Hits	310	Shared Neighborhood Hits	51
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

KRA92_HUMAN
θ value	θ > 10 (rank : 257)	NC score	0.051602 (rank : 330)
Query Neighborhood Hits	153	Target Neighborhood Hits	198	Shared Neighborhood Hits	41
SwissProt Accessions	Q9BYQ4	Gene names	KRTAP9-2, KAP9.2, KRTAP9.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-2 (Keratin-associated protein 9.2) (Ultrahigh sulfur keratin-associated protein 9.2).

KRA93_HUMAN
θ value	θ > 10 (rank : 258)	NC score	0.058322 (rank : 287)
Query Neighborhood Hits	153	Target Neighborhood Hits	203	Shared Neighborhood Hits	44
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

KRA94_HUMAN
θ value	θ > 10 (rank : 259)	NC score	0.054800 (rank : 309)
Query Neighborhood Hits	153	Target Neighborhood Hits	204	Shared Neighborhood Hits	47
SwissProt Accessions	Q9BYQ2	Gene names	KRTAP9-4, KAP9.4, KRTAP9.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-4 (Keratin-associated protein 9.4) (Ultrahigh sulfur keratin-associated protein 9.4).

KRA98_HUMAN
θ value	θ > 10 (rank : 260)	NC score	0.057865 (rank : 294)
Query Neighborhood Hits	153	Target Neighborhood Hits	185	Shared Neighborhood Hits	41
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

KRA99_HUMAN
θ value	θ > 10 (rank : 261)	NC score	0.051458 (rank : 334)
Query Neighborhood Hits	153	Target Neighborhood Hits	173	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BYP9	Gene names	KRTAP9-9, KAP9.9, KRTAP9.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-9 (Keratin-associated protein 9.9) (Ultrahigh sulfur keratin-associated protein 9.9).

KREM1_HUMAN
θ value	θ > 10 (rank : 262)	NC score	0.054993 (rank : 308)
Query Neighborhood Hits	153	Target Neighborhood Hits	90	Shared Neighborhood Hits	12
SwissProt Accessions	Q96MU8, Q5TIB9, Q6P3X6, Q9BY70, Q9UGS5, Q9UGU1	Gene names	KREMEN1, KREMEN, KRM1
Domain Architecture
Description	Kremen protein 1 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 1) (Dickkopf receptor).

KREM1_MOUSE
θ value	θ > 10 (rank : 263)	NC score	0.057935 (rank : 293)
Query Neighborhood Hits	153	Target Neighborhood Hits	92	Shared Neighborhood Hits	13
SwissProt Accessions	Q99N43	Gene names	Kremen1, Kremen
Domain Architecture
Description	Kremen protein 1 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 1) (Dickkopf receptor).

KREM2_HUMAN
θ value	θ > 10 (rank : 264)	NC score	0.057150 (rank : 296)
Query Neighborhood Hits	153	Target Neighborhood Hits	93	Shared Neighborhood Hits	12
SwissProt Accessions	Q8NCW0, Q8N2J4, Q8NCW1, Q96GL8, Q9BTP9	Gene names	KREMEN2, KRM2
Domain Architecture
Description	Kremen protein 2 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 2) (Dickkopf receptor 2).

KREM2_MOUSE
θ value	θ > 10 (rank : 265)	NC score	0.052081 (rank : 327)
Query Neighborhood Hits	153	Target Neighborhood Hits	90	Shared Neighborhood Hits	10
SwissProt Accessions	Q8K1S7	Gene names	Kremen2
Domain Architecture
Description	Kremen protein 2 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 2) (Dickkopf receptor 2).

LAMA1_HUMAN
θ value	θ > 10 (rank : 266)	NC score	0.057539 (rank : 295)
Query Neighborhood Hits	153	Target Neighborhood Hits	804	Shared Neighborhood Hits	62
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMA1_MOUSE
θ value	θ > 10 (rank : 267)	NC score	0.060537 (rank : 268)
Query Neighborhood Hits	153	Target Neighborhood Hits	838	Shared Neighborhood Hits	68
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMA2_HUMAN
θ value	θ > 10 (rank : 268)	NC score	0.061966 (rank : 258)
Query Neighborhood Hits	153	Target Neighborhood Hits	1092	Shared Neighborhood Hits	73
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LAMA2_MOUSE
θ value	θ > 10 (rank : 269)	NC score	0.054791 (rank : 310)
Query Neighborhood Hits	153	Target Neighborhood Hits	1198	Shared Neighborhood Hits	70
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LAMA5_MOUSE
θ value	θ > 10 (rank : 270)	NC score	0.072791 (rank : 207)
Query Neighborhood Hits	153	Target Neighborhood Hits	828	Shared Neighborhood Hits	69
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LAMB1_HUMAN
θ value	θ > 10 (rank : 271)	NC score	0.056123 (rank : 302)
Query Neighborhood Hits	153	Target Neighborhood Hits	1018	Shared Neighborhood Hits	64
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

LAMB1_MOUSE
θ value	θ > 10 (rank : 272)	NC score	0.058248 (rank : 288)
Query Neighborhood Hits	153	Target Neighborhood Hits	919	Shared Neighborhood Hits	63
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

LAMB2_MOUSE
θ value	θ > 10 (rank : 273)	NC score	0.064843 (rank : 238)
Query Neighborhood Hits	153	Target Neighborhood Hits	722	Shared Neighborhood Hits	64
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

LAMB3_MOUSE
θ value	θ > 10 (rank : 274)	NC score	0.052433 (rank : 324)
Query Neighborhood Hits	153	Target Neighborhood Hits	444	Shared Neighborhood Hits	54
SwissProt Accessions	Q61087	Gene names	Lamb3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Kalinin B1 chain).

LAMC1_MOUSE
θ value	θ > 10 (rank : 275)	NC score	0.050948 (rank : 337)
Query Neighborhood Hits	153	Target Neighborhood Hits	856	Shared Neighborhood Hits	61
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

LAMC2_HUMAN
θ value	θ > 10 (rank : 276)	NC score	0.050099 (rank : 342)
Query Neighborhood Hits	153	Target Neighborhood Hits	715	Shared Neighborhood Hits	59
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

LAMC3_HUMAN
θ value	θ > 10 (rank : 277)	NC score	0.076341 (rank : 184)
Query Neighborhood Hits	153	Target Neighborhood Hits	588	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LCE1B_HUMAN
θ value	θ > 10 (rank : 278)	NC score	0.065536 (rank : 235)
Query Neighborhood Hits	153	Target Neighborhood Hits	58	Shared Neighborhood Hits	18
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

LCE1C_HUMAN
θ value	θ > 10 (rank : 279)	NC score	0.064763 (rank : 239)
Query Neighborhood Hits	153	Target Neighborhood Hits	65	Shared Neighborhood Hits	18
SwissProt Accessions	Q5T751	Gene names	LCE1C, LEP3
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1C (Late envelope protein 3).

LCE1D_HUMAN
θ value	θ > 10 (rank : 280)	NC score	0.058804 (rank : 281)
Query Neighborhood Hits	153	Target Neighborhood Hits	44	Shared Neighborhood Hits	12
SwissProt Accessions	Q5T752	Gene names	LCE1D, LEP4
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1D (Late envelope protein 4).

LCE1E_HUMAN
θ value	θ > 10 (rank : 281)	NC score	0.061678 (rank : 260)
Query Neighborhood Hits	153	Target Neighborhood Hits	53	Shared Neighborhood Hits	14
SwissProt Accessions	Q5T753	Gene names	LCE1E, LEP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1E (Late envelope protein 5).

LCE1F_HUMAN
θ value	θ > 10 (rank : 282)	NC score	0.058426 (rank : 284)
Query Neighborhood Hits	153	Target Neighborhood Hits	48	Shared Neighborhood Hits	14
SwissProt Accessions	Q5T754	Gene names	LCE1F, LEP6
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1F (Late envelope protein 6).

LCE2C_HUMAN
θ value	θ > 10 (rank : 283)	NC score	0.052782 (rank : 322)
Query Neighborhood Hits	153	Target Neighborhood Hits	53	Shared Neighborhood Hits	13
SwissProt Accessions	Q5TA81	Gene names	LCE2C, LEP11
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2C (Late envelope protein 11).

LCE3A_HUMAN
θ value	θ > 10 (rank : 284)	NC score	0.051013 (rank : 336)
Query Neighborhood Hits	153	Target Neighborhood Hits	29	Shared Neighborhood Hits	9
SwissProt Accessions	Q5TA76	Gene names	LCE3A, LEP13
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3A (Late envelope protein 13).

LDLR_HUMAN
θ value	θ > 10 (rank : 285)	NC score	0.057988 (rank : 292)
Query Neighborhood Hits	153	Target Neighborhood Hits	375	Shared Neighborhood Hits	63
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LDLR_MOUSE
θ value	θ > 10 (rank : 286)	NC score	0.050244 (rank : 341)
Query Neighborhood Hits	153	Target Neighborhood Hits	382	Shared Neighborhood Hits	62
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LRP12_HUMAN
θ value	θ > 10 (rank : 287)	NC score	0.069061 (rank : 221)
Query Neighborhood Hits	153	Target Neighborhood Hits	205	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y561	Gene names	LRP12, ST7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor (Suppressor of tumorigenicity protein 7).

LRP12_MOUSE
θ value	θ > 10 (rank : 288)	NC score	0.068395 (rank : 224)
Query Neighborhood Hits	153	Target Neighborhood Hits	180	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BUJ9, Q8BWM9	Gene names	Lrp12
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor.

LRP1B_HUMAN
θ value	θ > 10 (rank : 289)	NC score	0.058388 (rank : 286)
Query Neighborhood Hits	153	Target Neighborhood Hits	602	Shared Neighborhood Hits	75
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LRP1B_MOUSE
θ value	θ > 10 (rank : 290)	NC score	0.059074 (rank : 277)
Query Neighborhood Hits	153	Target Neighborhood Hits	606	Shared Neighborhood Hits	75
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LRP1_HUMAN
θ value	θ > 10 (rank : 291)	NC score	0.059094 (rank : 276)
Query Neighborhood Hits	153	Target Neighborhood Hits	617	Shared Neighborhood Hits	74
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

LRP3_HUMAN
θ value	θ > 10 (rank : 292)	NC score	0.055305 (rank : 305)
Query Neighborhood Hits	153	Target Neighborhood Hits	280	Shared Neighborhood Hits	37
SwissProt Accessions	O75074	Gene names	LRP3
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 3 precursor (hLRp105).

LRP8_MOUSE
θ value	θ > 10 (rank : 293)	NC score	0.051646 (rank : 329)
Query Neighborhood Hits	153	Target Neighborhood Hits	385	Shared Neighborhood Hits	62
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

LTB1L_MOUSE
θ value	θ > 10 (rank : 294)	NC score	0.088242 (rank : 138)
Query Neighborhood Hits	153	Target Neighborhood Hits	514	Shared Neighborhood Hits	70
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_MOUSE
θ value	θ > 10 (rank : 295)	NC score	0.088284 (rank : 137)
Query Neighborhood Hits	153	Target Neighborhood Hits	479	Shared Neighborhood Hits	67
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTBP2_HUMAN
θ value	θ > 10 (rank : 296)	NC score	0.107301 (rank : 99)
Query Neighborhood Hits	153	Target Neighborhood Hits	552	Shared Neighborhood Hits	81
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LTBP3_HUMAN
θ value	θ > 10 (rank : 297)	NC score	0.098508 (rank : 115)
Query Neighborhood Hits	153	Target Neighborhood Hits	502	Shared Neighborhood Hits	81
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

MATN2_HUMAN
θ value	θ > 10 (rank : 298)	NC score	0.075031 (rank : 191)
Query Neighborhood Hits	153	Target Neighborhood Hits	365	Shared Neighborhood Hits	60
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

MATN2_MOUSE
θ value	θ > 10 (rank : 299)	NC score	0.073006 (rank : 204)
Query Neighborhood Hits	153	Target Neighborhood Hits	356	Shared Neighborhood Hits	59
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

MATN3_HUMAN
θ value	θ > 10 (rank : 300)	NC score	0.051523 (rank : 332)
Query Neighborhood Hits	153	Target Neighborhood Hits	268	Shared Neighborhood Hits	49
SwissProt Accessions	O15232	Gene names	MATN3
Domain Architecture
Description	Matrilin-3 precursor.

MATN3_MOUSE
θ value	θ > 10 (rank : 301)	NC score	0.051751 (rank : 328)
Query Neighborhood Hits	153	Target Neighborhood Hits	261	Shared Neighborhood Hits	51
SwissProt Accessions	O35701, Q9JHM0	Gene names	Matn3
Domain Architecture
Description	Matrilin-3 precursor.

MATN4_HUMAN
θ value	θ > 10 (rank : 302)	NC score	0.059744 (rank : 271)
Query Neighborhood Hits	153	Target Neighborhood Hits	287	Shared Neighborhood Hits	56
SwissProt Accessions	O95460, Q5QPU2, Q5QPU3, Q5QPU4, Q8N2M5, Q8N2M7, Q9H1F8, Q9H1F9	Gene names	MATN4
Domain Architecture
Description	Matrilin-4 precursor.

MATN4_MOUSE
θ value	θ > 10 (rank : 303)	NC score	0.055442 (rank : 304)
Query Neighborhood Hits	153	Target Neighborhood Hits	277	Shared Neighborhood Hits	56
SwissProt Accessions	O89029, O89030, Q9QWS3	Gene names	Matn4
Domain Architecture
Description	Matrilin-4 precursor (MAT-4).

MEGF9_HUMAN
θ value	θ > 10 (rank : 304)	NC score	0.074176 (rank : 198)
Query Neighborhood Hits	153	Target Neighborhood Hits	557	Shared Neighborhood Hits	67
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MEGF9_MOUSE
θ value	θ > 10 (rank : 305)	NC score	0.059280 (rank : 275)
Query Neighborhood Hits	153	Target Neighborhood Hits	896	Shared Neighborhood Hits	63
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MFRP_HUMAN
θ value	θ > 10 (rank : 306)	NC score	0.075813 (rank : 188)
Query Neighborhood Hits	153	Target Neighborhood Hits	165	Shared Neighborhood Hits	17
SwissProt Accessions	Q9BY79, Q335M3, Q96DQ9	Gene names	MFRP
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

MFRP_MOUSE
θ value	θ > 10 (rank : 307)	NC score	0.079629 (rank : 168)
Query Neighborhood Hits	153	Target Neighborhood Hits	166	Shared Neighborhood Hits	15
SwissProt Accessions	Q8K480, Q8BPP4	Gene names	Mfrp
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

NAGPA_MOUSE
θ value	θ > 10 (rank : 308)	NC score	0.078763 (rank : 174)
Query Neighborhood Hits	153	Target Neighborhood Hits	308	Shared Neighborhood Hits	59
SwissProt Accessions	Q8BJ48, Q3UUT5, Q8CHQ8, Q9QZE6	Gene names	Nagpa
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

NELL1_HUMAN
θ value	θ > 10 (rank : 309)	NC score	0.079372 (rank : 170)
Query Neighborhood Hits	153	Target Neighborhood Hits	451	Shared Neighborhood Hits	73
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

NELL2_HUMAN
θ value	θ > 10 (rank : 310)	NC score	0.078783 (rank : 173)
Query Neighborhood Hits	153	Target Neighborhood Hits	449	Shared Neighborhood Hits	68
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

NELL2_MOUSE
θ value	θ > 10 (rank : 311)	NC score	0.080197 (rank : 163)
Query Neighborhood Hits	153	Target Neighborhood Hits	436	Shared Neighborhood Hits	71
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

NETO1_HUMAN
θ value	θ > 10 (rank : 312)	NC score	0.061936 (rank : 259)
Query Neighborhood Hits	153	Target Neighborhood Hits	110	Shared Neighborhood Hits	15
SwissProt Accessions	Q8TDF5, Q86W85, Q8ND78, Q8TDF4	Gene names	NETO1, BTCL1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

NETO1_MOUSE
θ value	θ > 10 (rank : 313)	NC score	0.062210 (rank : 254)
Query Neighborhood Hits	153	Target Neighborhood Hits	109	Shared Neighborhood Hits	15
SwissProt Accessions	Q8R4I7, Q80X39, Q8C4S3, Q8CCM2	Gene names	Neto1, Btcl1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

NETO2_HUMAN
θ value	θ > 10 (rank : 314)	NC score	0.061193 (rank : 264)
Query Neighborhood Hits	153	Target Neighborhood Hits	109	Shared Neighborhood Hits	15
SwissProt Accessions	Q8NC67, Q7Z381, Q8ND51, Q96SP4, Q9NVY8	Gene names	NETO2, BTCL2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

NETO2_MOUSE
θ value	θ > 10 (rank : 315)	NC score	0.061009 (rank : 266)
Query Neighborhood Hits	153	Target Neighborhood Hits	113	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BNJ6, Q5VM49, Q8C4Q8	Gene names	Neto2, Btcl2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

NFX1_HUMAN
θ value	θ > 10 (rank : 316)	NC score	0.062088 (rank : 257)
Query Neighborhood Hits	153	Target Neighborhood Hits	405	Shared Neighborhood Hits	49
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

NID1_HUMAN
θ value	θ > 10 (rank : 317)	NC score	0.064360 (rank : 242)
Query Neighborhood Hits	153	Target Neighborhood Hits	329	Shared Neighborhood Hits	62
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

NID1_MOUSE
θ value	θ > 10 (rank : 318)	NC score	0.060917 (rank : 267)
Query Neighborhood Hits	153	Target Neighborhood Hits	335	Shared Neighborhood Hits	58
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

NID2_HUMAN
θ value	θ > 10 (rank : 319)	NC score	0.059570 (rank : 273)
Query Neighborhood Hits	153	Target Neighborhood Hits	456	Shared Neighborhood Hits	58
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

NID2_MOUSE
θ value	θ > 10 (rank : 320)	NC score	0.061305 (rank : 262)
Query Neighborhood Hits	153	Target Neighborhood Hits	338	Shared Neighborhood Hits	56
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

NRP1_HUMAN
θ value	θ > 10 (rank : 321)	NC score	0.061145 (rank : 265)
Query Neighborhood Hits	153	Target Neighborhood Hits	119	Shared Neighborhood Hits	14
SwissProt Accessions	O14786, O60461, Q96IH5	Gene names	NRP1, NRP, VEGF165R
Domain Architecture
Description	Neuropilin-1 precursor (Vascular endothelial cell growth factor 165 receptor) (CD304 antigen).

NRP1_MOUSE
θ value	θ > 10 (rank : 322)	NC score	0.062207 (rank : 255)
Query Neighborhood Hits	153	Target Neighborhood Hits	120	Shared Neighborhood Hits	13
SwissProt Accessions	P97333	Gene names	Nrp1, Nrp
Domain Architecture
Description	Neuropilin-1 precursor (A5 protein).

NRP2_HUMAN
θ value	θ > 10 (rank : 323)	NC score	0.068306 (rank : 225)
Query Neighborhood Hits	153	Target Neighborhood Hits	120	Shared Neighborhood Hits	14
SwissProt Accessions	O60462, O14820, O14821	Gene names	NRP2, VEGF165R2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

NRP2_MOUSE
θ value	θ > 10 (rank : 324)	NC score	0.068813 (rank : 223)
Query Neighborhood Hits	153	Target Neighborhood Hits	113	Shared Neighborhood Hits	14
SwissProt Accessions	O35375, O35373, O35374, O35376, O35377, O35378	Gene names	Nrp2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

PCOC1_HUMAN
θ value	θ > 10 (rank : 325)	NC score	0.085643 (rank : 147)
Query Neighborhood Hits	153	Target Neighborhood Hits	146	Shared Neighborhood Hits	13
SwissProt Accessions	Q15113, O14550	Gene names	PCOLCE, PCPE1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein).

PCOC1_MOUSE
θ value	θ > 10 (rank : 326)	NC score	0.084588 (rank : 151)
Query Neighborhood Hits	153	Target Neighborhood Hits	100	Shared Neighborhood Hits	12
SwissProt Accessions	Q61398, O35113	Gene names	Pcolce, Pcpe1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein) (P14).

PCOC2_HUMAN
θ value	θ > 10 (rank : 327)	NC score	0.077334 (rank : 178)
Query Neighborhood Hits	153	Target Neighborhood Hits	73	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UKZ9, Q9BRH3	Gene names	PCOLCE2, PCPE2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

PCOC2_MOUSE
θ value	θ > 10 (rank : 328)	NC score	0.075510 (rank : 189)
Query Neighborhood Hits	153	Target Neighborhood Hits	73	Shared Neighborhood Hits	12
SwissProt Accessions	Q8R4W6, Q3V1K6, Q9CX06	Gene names	Pcolce2, Pcpe2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

PDGFD_HUMAN
θ value	θ > 10 (rank : 329)	NC score	0.069560 (rank : 219)
Query Neighborhood Hits	153	Target Neighborhood Hits	74	Shared Neighborhood Hits	12
SwissProt Accessions	Q9GZP0, Q9BWV5	Gene names	PDGFD, IEGF, SCDGFB
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor D precursor (PDGF D) (Iris-expressed growth factor) (Spinal cord-derived growth factor B) (SCDGF-B).

PDGFD_MOUSE
θ value	θ > 10 (rank : 330)	NC score	0.069339 (rank : 220)
Query Neighborhood Hits	153	Target Neighborhood Hits	72	Shared Neighborhood Hits	11
SwissProt Accessions	Q925I7, Q3URF6, Q8K2L3, Q9D1L8	Gene names	Pdgfd, Scdgfb
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor chain precursor (PDGF D) (Spinal cord- derived growth factor B) (SCDGF-B).

PERT_HUMAN
θ value	θ > 10 (rank : 331)	NC score	0.112524 (rank : 88)
Query Neighborhood Hits	153	Target Neighborhood Hits	221	Shared Neighborhood Hits	74
SwissProt Accessions	P07202, P09934, P09935, Q8IUL0, Q8NF94, Q8NF95, Q8NF96, Q8NF97, Q8TCI9	Gene names	TPO
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

PERT_MOUSE
θ value	θ > 10 (rank : 332)	NC score	0.120961 (rank : 79)
Query Neighborhood Hits	153	Target Neighborhood Hits	221	Shared Neighborhood Hits	80
SwissProt Accessions	P35419, Q8C8B1	Gene names	Tpo
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

PGCA_HUMAN
θ value	θ > 10 (rank : 333)	NC score	0.076544 (rank : 183)
Query Neighborhood Hits	153	Target Neighborhood Hits	821	Shared Neighborhood Hits	75
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

PGCA_MOUSE
θ value	θ > 10 (rank : 334)	NC score	0.066892 (rank : 231)
Query Neighborhood Hits	153	Target Neighborhood Hits	643	Shared Neighborhood Hits	44
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

PGCB_HUMAN
θ value	θ > 10 (rank : 335)	NC score	0.084831 (rank : 149)
Query Neighborhood Hits	153	Target Neighborhood Hits	478	Shared Neighborhood Hits	68
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

PGCB_MOUSE
θ value	θ > 10 (rank : 336)	NC score	0.075902 (rank : 187)
Query Neighborhood Hits	153	Target Neighborhood Hits	459	Shared Neighborhood Hits	66
SwissProt Accessions	Q61361	Gene names	Bcan
Domain Architecture
Description	Brevican core protein precursor.

PROC_HUMAN
θ value	θ > 10 (rank : 337)	NC score	0.051553 (rank : 331)
Query Neighborhood Hits	153	Target Neighborhood Hits	406	Shared Neighborhood Hits	57
SwissProt Accessions	P04070, Q15189, Q15190, Q16001	Gene names	PROC
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

PROC_MOUSE
θ value	θ > 10 (rank : 338)	NC score	0.056246 (rank : 301)
Query Neighborhood Hits	153	Target Neighborhood Hits	426	Shared Neighborhood Hits	59
SwissProt Accessions	P33587, O35498, Q91WN8, Q99PC6	Gene names	Proc
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

PROS_HUMAN
θ value	θ > 10 (rank : 339)	NC score	0.076303 (rank : 185)
Query Neighborhood Hits	153	Target Neighborhood Hits	340	Shared Neighborhood Hits	61
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

PROS_MOUSE
θ value	θ > 10 (rank : 340)	NC score	0.074122 (rank : 199)
Query Neighborhood Hits	153	Target Neighborhood Hits	330	Shared Neighborhood Hits	60
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

PROZ_HUMAN
θ value	θ > 10 (rank : 341)	NC score	0.076142 (rank : 186)
Query Neighborhood Hits	153	Target Neighborhood Hits	422	Shared Neighborhood Hits	60
SwissProt Accessions	P22891, Q15213	Gene names	PROZ
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

PROZ_MOUSE
θ value	θ > 10 (rank : 342)	NC score	0.080735 (rank : 161)
Query Neighborhood Hits	153	Target Neighborhood Hits	410	Shared Neighborhood Hits	58
SwissProt Accessions	Q9CQW3	Gene names	Proz
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

SCUB3_HUMAN
θ value	θ > 10 (rank : 343)	NC score	0.097628 (rank : 117)
Query Neighborhood Hits	153	Target Neighborhood Hits	428	Shared Neighborhood Hits	65
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SCUB3_MOUSE
θ value	θ > 10 (rank : 344)	NC score	0.096127 (rank : 120)
Query Neighborhood Hits	153	Target Neighborhood Hits	442	Shared Neighborhood Hits	65
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SLIT1_HUMAN
θ value	θ > 10 (rank : 345)	NC score	0.055180 (rank : 306)
Query Neighborhood Hits	153	Target Neighborhood Hits	700	Shared Neighborhood Hits	68
SwissProt Accessions	O75093, Q8WWZ2, Q9UIL7	Gene names	SLIT1, KIAA0813, MEGF4, SLIL1
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1) (Multiple epidermal growth factor-like domains 4).

SLIT1_MOUSE
θ value	θ > 10 (rank : 346)	NC score	0.053000 (rank : 320)
Query Neighborhood Hits	153	Target Neighborhood Hits	715	Shared Neighborhood Hits	69
SwissProt Accessions	Q80TR4, Q9WVB5	Gene names	Slit1, Kiaa0813
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1).

SLIT2_HUMAN
θ value	θ > 10 (rank : 347)	NC score	0.053935 (rank : 313)
Query Neighborhood Hits	153	Target Neighborhood Hits	708	Shared Neighborhood Hits	70
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

SLIT2_MOUSE
θ value	θ > 10 (rank : 348)	NC score	0.053085 (rank : 319)
Query Neighborhood Hits	153	Target Neighborhood Hits	684	Shared Neighborhood Hits	70
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

SLIT3_HUMAN
θ value	θ > 10 (rank : 349)	NC score	0.052165 (rank : 325)
Query Neighborhood Hits	153	Target Neighborhood Hits	682	Shared Neighborhood Hits	64
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

SLIT3_MOUSE
θ value	θ > 10 (rank : 350)	NC score	0.053898 (rank : 314)
Query Neighborhood Hits	153	Target Neighborhood Hits	700	Shared Neighborhood Hits	66
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

ST14_HUMAN
θ value	θ > 10 (rank : 351)	NC score	0.050054 (rank : 343)
Query Neighborhood Hits	153	Target Neighborhood Hits	409	Shared Neighborhood Hits	54
SwissProt Accessions	Q9Y5Y6, Q9BS01, Q9H3S0, Q9HB36, Q9HCA3	Gene names	ST14, PRSS14, SNC19, TADG15
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Matriptase) (Membrane-type serine protease 1) (MT-SP1) (Prostamin) (Serine protease TADG-15) (Tumor-associated differentially-expressed gene 15 protein).

STAB1_HUMAN
θ value	θ > 10 (rank : 352)	NC score	0.080603 (rank : 162)
Query Neighborhood Hits	153	Target Neighborhood Hits	546	Shared Neighborhood Hits	70
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

STAB1_MOUSE
θ value	θ > 10 (rank : 353)	NC score	0.086787 (rank : 141)
Query Neighborhood Hits	153	Target Neighborhood Hits	566	Shared Neighborhood Hits	72
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

STAB2_HUMAN
θ value	θ > 10 (rank : 354)	NC score	0.082557 (rank : 155)
Query Neighborhood Hits	153	Target Neighborhood Hits	534	Shared Neighborhood Hits	71
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

SUSD2_HUMAN
θ value	θ > 10 (rank : 355)	NC score	0.213759 (rank : 49)
Query Neighborhood Hits	153	Target Neighborhood Hits	99	Shared Neighborhood Hits	56
SwissProt Accessions	Q9UGT4, Q9H5Y6	Gene names	SUSD2
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 2 precursor.

SUSD2_MOUSE
θ value	θ > 10 (rank : 356)	NC score	0.224462 (rank : 48)
Query Neighborhood Hits	153	Target Neighborhood Hits	104	Shared Neighborhood Hits	59
SwissProt Accessions	Q9DBX3, Q8BY19, Q8BYN0, Q8BYZ3, Q8BYZ9, Q8BZQ4, Q8C179	Gene names	Susd2
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 2 precursor.

SUSD3_HUMAN
θ value	θ > 10 (rank : 357)	NC score	0.102058 (rank : 111)
Query Neighborhood Hits	153	Target Neighborhood Hits	32	Shared Neighborhood Hits	23
SwissProt Accessions	Q96L08, Q49AA6, Q6UXV7	Gene names	SUSD3, UNQ9387/PRO34275
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 3.

SUSD3_MOUSE
θ value	θ > 10 (rank : 358)	NC score	0.182944 (rank : 52)
Query Neighborhood Hits	153	Target Neighborhood Hits	39	Shared Neighborhood Hits	30
SwissProt Accessions	Q9D176, Q80XL5, Q9CYV1, Q9DA86	Gene names	Susd3
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 3.

TENA_HUMAN
θ value	θ > 10 (rank : 359)	NC score	0.071334 (rank : 213)
Query Neighborhood Hits	153	Target Neighborhood Hits	631	Shared Neighborhood Hits	68
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

TENA_MOUSE
θ value	θ > 10 (rank : 360)	NC score	0.071273 (rank : 214)
Query Neighborhood Hits	153	Target Neighborhood Hits	596	Shared Neighborhood Hits	68
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

TENX_HUMAN
θ value	θ > 10 (rank : 361)	NC score	0.075270 (rank : 190)
Query Neighborhood Hits	153	Target Neighborhood Hits	789	Shared Neighborhood Hits	71
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

TLL1_HUMAN
θ value	θ > 10 (rank : 362)	NC score	0.105352 (rank : 105)
Query Neighborhood Hits	153	Target Neighborhood Hits	236	Shared Neighborhood Hits	46
SwissProt Accessions	O43897, Q96AN3, Q9NQS4	Gene names	TLL1, TLL
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-).

TLL1_MOUSE
θ value	θ > 10 (rank : 363)	NC score	0.108161 (rank : 94)
Query Neighborhood Hits	153	Target Neighborhood Hits	237	Shared Neighborhood Hits	47
SwissProt Accessions	Q62381, Q3UTT9, Q8BNP5	Gene names	Tll1, Tll
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-) (mTll).

TLL2_HUMAN
θ value	θ > 10 (rank : 364)	NC score	0.105873 (rank : 104)
Query Neighborhood Hits	153	Target Neighborhood Hits	241	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Y6L7, Q6PJN5, Q9UQ00	Gene names	TLL2, KIAA0932
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

TLL2_MOUSE
θ value	θ > 10 (rank : 365)	NC score	0.107431 (rank : 97)
Query Neighborhood Hits	153	Target Neighborhood Hits	240	Shared Neighborhood Hits	48
SwissProt Accessions	Q9WVM6	Gene names	Tll2
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

TRBM_HUMAN
θ value	θ > 10 (rank : 366)	NC score	0.073587 (rank : 201)
Query Neighborhood Hits	153	Target Neighborhood Hits	339	Shared Neighborhood Hits	67
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

TRBM_MOUSE
θ value	θ > 10 (rank : 367)	NC score	0.072885 (rank : 206)
Query Neighborhood Hits	153	Target Neighborhood Hits	361	Shared Neighborhood Hits	62
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

TSG6_HUMAN
θ value	θ > 10 (rank : 368)	NC score	0.070188 (rank : 217)
Query Neighborhood Hits	153	Target Neighborhood Hits	91	Shared Neighborhood Hits	15
SwissProt Accessions	P98066, Q8WWI9	Gene names	TNFAIP6, TSG6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein) (Hyaluronate-binding protein).

TSG6_MOUSE
θ value	θ > 10 (rank : 369)	NC score	0.070497 (rank : 215)
Query Neighborhood Hits	153	Target Neighborhood Hits	91	Shared Neighborhood Hits	15
SwissProt Accessions	O08859	Gene names	Tnfaip6, Tnfip6, Tsg6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein).

TSP1_HUMAN
θ value	θ > 10 (rank : 370)	NC score	0.054121 (rank : 311)
Query Neighborhood Hits	153	Target Neighborhood Hits	389	Shared Neighborhood Hits	62
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

TSP3_HUMAN
θ value	θ > 10 (rank : 371)	NC score	0.050316 (rank : 340)
Query Neighborhood Hits	153	Target Neighborhood Hits	250	Shared Neighborhood Hits	42
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

TSP3_MOUSE
θ value	θ > 10 (rank : 372)	NC score	0.050586 (rank : 339)
Query Neighborhood Hits	153	Target Neighborhood Hits	247	Shared Neighborhood Hits	43
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

TSP4_HUMAN
θ value	θ > 10 (rank : 373)	NC score	0.058458 (rank : 283)
Query Neighborhood Hits	153	Target Neighborhood Hits	277	Shared Neighborhood Hits	48
SwissProt Accessions	P35443, Q86TG2	Gene names	THBS4, TSP4
Domain Architecture
Description	Thrombospondin-4 precursor.

TSP4_MOUSE
θ value	θ > 10 (rank : 374)	NC score	0.056344 (rank : 300)
Query Neighborhood Hits	153	Target Neighborhood Hits	276	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Z1T2, Q9QYS3, Q9WUE0	Gene names	Thbs4, Tsp4
Domain Architecture
Description	Thrombospondin-4 precursor.

UROM_HUMAN
θ value	θ > 10 (rank : 375)	NC score	0.067781 (rank : 228)
Query Neighborhood Hits	153	Target Neighborhood Hits	284	Shared Neighborhood Hits	53
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

UROM_MOUSE
θ value	θ > 10 (rank : 376)	NC score	0.064975 (rank : 237)
Query Neighborhood Hits	153	Target Neighborhood Hits	276	Shared Neighborhood Hits	51
SwissProt Accessions	Q91X17, Q3TN64, Q3TP60, Q62285	Gene names	Umod
Domain Architecture	No domain graphic available
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

USH2A_HUMAN
θ value	θ > 10 (rank : 377)	NC score	0.063155 (rank : 248)
Query Neighborhood Hits	153	Target Neighborhood Hits	600	Shared Neighborhood Hits	59
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

VLDLR_HUMAN
θ value	θ > 10 (rank : 378)	NC score	0.050650 (rank : 338)
Query Neighborhood Hits	153	Target Neighborhood Hits	383	Shared Neighborhood Hits	63
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

WIF1_HUMAN
θ value	θ > 10 (rank : 379)	NC score	0.078991 (rank : 171)
Query Neighborhood Hits	153	Target Neighborhood Hits	392	Shared Neighborhood Hits	68
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

WIF1_MOUSE
θ value	θ > 10 (rank : 380)	NC score	0.079656 (rank : 167)
Query Neighborhood Hits	153	Target Neighborhood Hits	393	Shared Neighborhood Hits	66
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

ZAN_HUMAN
θ value	θ > 10 (rank : 381)	NC score	0.056886 (rank : 297)
Query Neighborhood Hits	153	Target Neighborhood Hits	679	Shared Neighborhood Hits	65
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

Hits sorted by NC score

PAPPA_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 3)
Query Neighborhood Hits	153	Target Neighborhood Hits	153	Shared Neighborhood Hits	153
SwissProt Accessions	Q8R4K8, Q80VW3, Q80YY1, Q8K423, Q8R4K7, Q9ES06, Q9JK57	Gene names	Pappa
Domain Architecture	No domain graphic available
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

PAPPA_HUMAN
NC score	0.986435 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	153	Target Neighborhood Hits	161	Shared Neighborhood Hits	120
SwissProt Accessions	Q13219, Q08371, Q68G52, Q9UDK7	Gene names	PAPPA
Domain Architecture
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

PAP2_HUMAN
NC score	0.951476 (rank : 3)	θ value	0 (rank : 1)
Query Neighborhood Hits	153	Target Neighborhood Hits	106	Shared Neighborhood Hits	69
SwissProt Accessions	Q9BXP8, Q96PH7, Q96PH8, Q9H4C9	Gene names	PAPPA2
Domain Architecture	No domain graphic available
Description	Pappalysin-2 precursor (EC 3.4.24.-) (Pregnancy-associated plasma protein-A2) (PAPP-A2) (Pregnancy-associated plasma protein-E1) (PAPP- E).

DAF2_MOUSE
NC score	0.612051 (rank : 4)	θ value	7.09661e-13 (rank : 13)
Query Neighborhood Hits	153	Target Neighborhood Hits	114	Shared Neighborhood Hits	58
SwissProt Accessions	Q61476	Gene names	Cd55b, Daf2
Domain Architecture
Description	Complement decay-accelerating factor transmembrane isoform precursor (DAF-TM) (CD55 antigen).

DAF1_MOUSE
NC score	0.609093 (rank : 5)	θ value	4.91457e-14 (rank : 10)
Query Neighborhood Hits	153	Target Neighborhood Hits	204	Shared Neighborhood Hits	59
SwissProt Accessions	Q61475, P97732, Q61397	Gene names	Cd55a, Daf1
Domain Architecture
Description	Complement decay-accelerating factor, GPI-anchored precursor (DAF-GPI) (CD55 antigen).

DAF_HUMAN
NC score	0.603424 (rank : 6)	θ value	1.33837e-11 (rank : 15)
Query Neighborhood Hits	153	Target Neighborhood Hits	97	Shared Neighborhood Hits	57
SwissProt Accessions	P08174, P09679, P78361	Gene names	CD55, CR, DAF
Domain Architecture
Description	Complement decay-accelerating factor precursor (CD55 antigen).

CR1_HUMAN
NC score	0.569973 (rank : 7)	θ value	3.89403e-11 (rank : 16)
Query Neighborhood Hits	153	Target Neighborhood Hits	108	Shared Neighborhood Hits	61
SwissProt Accessions	P17927, Q16745, Q9UQV2	Gene names	CR1, C3BR
Domain Architecture
Description	Complement receptor type 1 precursor (C3b/C4b receptor) (CD35 antigen).

LYAM3_HUMAN
NC score	0.568108 (rank : 8)	θ value	2.5182e-18 (rank : 4)
Query Neighborhood Hits	153	Target Neighborhood Hits	378	Shared Neighborhood Hits	99
SwissProt Accessions	P16109, Q8IVD1	Gene names	SELP, GMRP
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

ZP3R_MOUSE
NC score	0.565445 (rank : 9)	θ value	1.80886e-08 (rank : 22)
Query Neighborhood Hits	153	Target Neighborhood Hits	81	Shared Neighborhood Hits	57
SwissProt Accessions	Q60736	Gene names	Zp3r, Sp56
Domain Architecture
Description	Zona pellucida sperm-binding protein 3 receptor precursor (Sperm fertilization protein 56) (sp56).

CR2_HUMAN
NC score	0.562105 (rank : 10)	θ value	1.63604e-09 (rank : 17)
Query Neighborhood Hits	153	Target Neighborhood Hits	89	Shared Neighborhood Hits	58
SwissProt Accessions	P20023, Q13866, Q14212	Gene names	CR2, C3DR
Domain Architecture
Description	Complement receptor type 2 precursor (Cr2) (Complement C3d receptor) (Epstein-Barr virus receptor) (EBV receptor) (CD21 antigen).

LYAM3_MOUSE
NC score	0.560967 (rank : 11)	θ value	5.25075e-16 (rank : 8)
Query Neighborhood Hits	153	Target Neighborhood Hits	390	Shared Neighborhood Hits	102
SwissProt Accessions	Q01102	Gene names	Selp, Grmp
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

CR2_MOUSE
NC score	0.560921 (rank : 12)	θ value	3.08544e-08 (rank : 24)
Query Neighborhood Hits	153	Target Neighborhood Hits	101	Shared Neighborhood Hits	60
SwissProt Accessions	P19070	Gene names	Cr2
Domain Architecture
Description	Complement receptor type 2 precursor (Cr2) (Complement C3d receptor) (CD21 antigen).

C4BP_HUMAN
NC score	0.559146 (rank : 13)	θ value	6.21693e-09 (rank : 19)
Query Neighborhood Hits	153	Target Neighborhood Hits	92	Shared Neighborhood Hits	59
SwissProt Accessions	P04003	Gene names	C4BPA, C4BP
Domain Architecture
Description	C4b-binding protein alpha chain precursor (C4bp) (Proline-rich protein) (PRP).

APOH_MOUSE
NC score	0.558787 (rank : 14)	θ value	1.80886e-08 (rank : 20)
Query Neighborhood Hits	153	Target Neighborhood Hits	74	Shared Neighborhood Hits	58
SwissProt Accessions	Q01339	Gene names	Apoh, B2gp1
Domain Architecture
Description	Beta-2-glycoprotein 1 precursor (Beta-2-glycoprotein I) (Apolipoprotein H) (Apo-H) (B2GPI) (Beta(2)GPI) (Activated protein C- binding protein) (APC inhibitor).

LYAM2_HUMAN
NC score	0.554102 (rank : 15)	θ value	4.29542e-18 (rank : 5)
Query Neighborhood Hits	153	Target Neighborhood Hits	394	Shared Neighborhood Hits	96
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

CRRY_MOUSE
NC score	0.550315 (rank : 16)	θ value	4.45536e-07 (rank : 26)
Query Neighborhood Hits	153	Target Neighborhood Hits	84	Shared Neighborhood Hits	57
SwissProt Accessions	Q64735, Q3TV30, Q58E68, Q61447, Q61449, Q8CF59, Q8K328	Gene names	Crry, Cry
Domain Architecture	No domain graphic available
Description	Complement regulatory protein Crry precursor (Protein p65).

CFAH_MOUSE
NC score	0.545714 (rank : 17)	θ value	6.00763e-12 (rank : 14)
Query Neighborhood Hits	153	Target Neighborhood Hits	112	Shared Neighborhood Hits	62
SwissProt Accessions	P06909	Gene names	Cfh, Hf1
Domain Architecture
Description	Complement factor H precursor (Protein beta-1-H).

C4BP_MOUSE
NC score	0.543805 (rank : 18)	θ value	0.000461057 (rank : 40)
Query Neighborhood Hits	153	Target Neighborhood Hits	91	Shared Neighborhood Hits	57
SwissProt Accessions	P08607	Gene names	C4bpa, C4bp
Domain Architecture
Description	C4b-binding protein precursor (C4bp).

SRPX_MOUSE
NC score	0.542376 (rank : 19)	θ value	2.36244e-08 (rank : 23)
Query Neighborhood Hits	153	Target Neighborhood Hits	75	Shared Neighborhood Hits	54
SwissProt Accessions	Q9R0M3, Q9R0M2	Gene names	Srpx
Domain Architecture	No domain graphic available
Description	Sushi-repeat-containing protein SRPX precursor (DRS protein).

SRPX_HUMAN
NC score	0.541868 (rank : 20)	θ value	2.79066e-09 (rank : 18)
Query Neighborhood Hits	153	Target Neighborhood Hits	69	Shared Neighborhood Hits	52
SwissProt Accessions	P78539, Q99652, Q99913	Gene names	SRPX, ETX1
Domain Architecture
Description	Sushi repeat-containing protein SRPX precursor.

LYAM2_MOUSE
NC score	0.540827 (rank : 21)	θ value	2.20605e-14 (rank : 9)
Query Neighborhood Hits	153	Target Neighborhood Hits	420	Shared Neighborhood Hits	100
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

C4BB_HUMAN
NC score	0.540518 (rank : 22)	θ value	0.000786445 (rank : 41)
Query Neighborhood Hits	153	Target Neighborhood Hits	77	Shared Neighborhood Hits	56
SwissProt Accessions	P20851	Gene names	C4BPB
Domain Architecture
Description	C4b-binding protein beta chain precursor.

CFAH_HUMAN
NC score	0.529648 (rank : 23)	θ value	1.80886e-08 (rank : 21)
Query Neighborhood Hits	153	Target Neighborhood Hits	101	Shared Neighborhood Hits	62
SwissProt Accessions	P08603, P78435, Q14570, Q38G77, Q5TFM3, Q8N708, Q9NU86	Gene names	CFH, HF, HF1
Domain Architecture
Description	Complement factor H precursor (H factor 1).

F13B_MOUSE
NC score	0.520499 (rank : 24)	θ value	3.77169e-06 (rank : 31)
Query Neighborhood Hits	153	Target Neighborhood Hits	93	Shared Neighborhood Hits	62
SwissProt Accessions	Q07968	Gene names	F13b, Cf13b
Domain Architecture
Description	Coagulation factor XIII B chain precursor (Protein-glutamine gamma- glutamyltransferase B chain) (Transglutaminase B chain).

F13B_HUMAN
NC score	0.514531 (rank : 25)	θ value	6.43352e-06 (rank : 32)
Query Neighborhood Hits	153	Target Neighborhood Hits	84	Shared Neighborhood Hits	54
SwissProt Accessions	P05160	Gene names	F13B
Domain Architecture
Description	Coagulation factor XIII B chain precursor (Protein-glutamine gamma- glutamyltransferase B chain) (Transglutaminase B chain) (Fibrin- stabilizing factor B subunit).

APOH_HUMAN
NC score	0.514007 (rank : 26)	θ value	0.0252991 (rank : 57)
Query Neighborhood Hits	153	Target Neighborhood Hits	75	Shared Neighborhood Hits	56
SwissProt Accessions	P02749, Q9UCN7	Gene names	APOH, B2G1
Domain Architecture
Description	Beta-2-glycoprotein 1 precursor (Beta-2-glycoprotein I) (Apolipoprotein H) (Apo-H) (B2GPI) (Beta(2)GPI) (Activated protein C- binding protein) (APC inhibitor) (Anticardiolipin cofactor).

MCP_MOUSE
NC score	0.494882 (rank : 27)	θ value	0.00134147 (rank : 44)
Query Neighborhood Hits	153	Target Neighborhood Hits	79	Shared Neighborhood Hits	57
SwissProt Accessions	O88174, Q9R0R9	Gene names	Cd46, Mcp
Domain Architecture	No domain graphic available
Description	Membrane cofactor protein precursor (CD46 antigen).

FHR5_HUMAN
NC score	0.481578 (rank : 28)	θ value	1.43324e-05 (rank : 34)
Query Neighborhood Hits	153	Target Neighborhood Hits	77	Shared Neighborhood Hits	54
SwissProt Accessions	Q9BXR6	Gene names	CFHL5, FHR5
Domain Architecture
Description	Complement factor H-related protein 5 precursor (FHR-5).

MCP_HUMAN
NC score	0.479214 (rank : 29)	θ value	0.163984 (rank : 71)
Query Neighborhood Hits	153	Target Neighborhood Hits	82	Shared Neighborhood Hits	56
SwissProt Accessions	P15529, Q15429, Q53GV9, Q5HY94, Q5VWS6, Q5VWS7, Q5VWS8, Q5VWS9, Q5VWT0, Q5VWT1, Q5VWT2, Q6N0A1, Q7Z3R5, Q9NNW2, Q9NNW3, Q9NNW4	Gene names	CD46, MCP
Domain Architecture
Description	Membrane cofactor protein precursor (Trophoblast leukocyte common antigen) (TLX) (CD46 antigen).

FHR1_HUMAN
NC score	0.477171 (rank : 30)	θ value	8.97725e-08 (rank : 25)
Query Neighborhood Hits	153	Target Neighborhood Hits	80	Shared Neighborhood Hits	57
SwissProt Accessions	Q03591, Q9UJ17	Gene names	CFHL1, CFHL, FHR1, HFL1
Domain Architecture
Description	Complement factor H-related protein 1 precursor (FHR-1) (H factor-like protein 1) (H-factor-like 1) (H36).

CSMD1_MOUSE
NC score	0.475194 (rank : 31)	θ value	8.10077e-17 (rank : 7)
Query Neighborhood Hits	153	Target Neighborhood Hits	193	Shared Neighborhood Hits	68
SwissProt Accessions	Q923L3, Q8BUV1, Q8BYQ3	Gene names	Csmd1
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

CSMD1_HUMAN
NC score	0.473211 (rank : 32)	θ value	8.10077e-17 (rank : 6)
Query Neighborhood Hits	153	Target Neighborhood Hits	176	Shared Neighborhood Hits	66
SwissProt Accessions	Q96PZ7, Q96QU9, Q96RM4	Gene names	CSMD1, KIAA1890
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

SUSD4_HUMAN
NC score	0.471505 (rank : 33)	θ value	0.00020696 (rank : 39)
Query Neighborhood Hits	153	Target Neighborhood Hits	88	Shared Neighborhood Hits	52
SwissProt Accessions	Q5VX71, Q6UX62, Q9BSR0, Q9NWG0	Gene names	SUSD4
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 4 precursor.

CSMD3_HUMAN
NC score	0.471202 (rank : 34)	θ value	1.42992e-13 (rank : 12)
Query Neighborhood Hits	153	Target Neighborhood Hits	199	Shared Neighborhood Hits	66
SwissProt Accessions	Q7Z407, Q96PZ3	Gene names	CSMD3, KIAA1894
Domain Architecture
Description	CUB and sushi domain-containing protein 3 precursor (CUB and sushi multiple domains protein 3).

CSMD2_HUMAN
NC score	0.461781 (rank : 35)	θ value	1.42992e-13 (rank : 11)
Query Neighborhood Hits	153	Target Neighborhood Hits	188	Shared Neighborhood Hits	63
SwissProt Accessions	Q7Z408, Q5VT59, Q8N963, Q96Q03, Q9H4V7, Q9H4V8, Q9H4V9, Q9H4W0, Q9H4W1, Q9H4W2, Q9H4W3, Q9H4W4, Q9HCY5, Q9HCY6, Q9HCY7	Gene names	CSMD2, KIAA1884
Domain Architecture
Description	CUB and sushi domain-containing protein 2 (CUB and sushi multiple domains protein 2).

FHR2_HUMAN
NC score	0.453822 (rank : 36)	θ value	2.21117e-06 (rank : 30)
Query Neighborhood Hits	153	Target Neighborhood Hits	63	Shared Neighborhood Hits	52
SwissProt Accessions	P36980, Q14310	Gene names	CFHL2, FHR2, HFL3
Domain Architecture
Description	Complement factor H-related protein 2 precursor (FHR-2) (H factor-like protein 2) (H factor-like 3) (DDESK59).

SUSD4_MOUSE
NC score	0.449887 (rank : 37)	θ value	0.0961366 (rank : 67)
Query Neighborhood Hits	153	Target Neighborhood Hits	122	Shared Neighborhood Hits	52
SwissProt Accessions	Q8BH32, Q8VC43	Gene names	Susd4
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 4 precursor.

FHR3_HUMAN
NC score	0.441933 (rank : 38)	θ value	0.00298849 (rank : 45)
Query Neighborhood Hits	153	Target Neighborhood Hits	74	Shared Neighborhood Hits	57
SwissProt Accessions	Q02985, Q9UJ16	Gene names	CFHL3, FHR3
Domain Architecture
Description	Complement factor H-related protein 3 precursor (FHR-3) (H factor-like protein 3) (DOWN16).

LYAM1_MOUSE
NC score	0.433922 (rank : 39)	θ value	4.45536e-07 (rank : 27)
Query Neighborhood Hits	153	Target Neighborhood Hits	332	Shared Neighborhood Hits	84
SwissProt Accessions	P18337	Gene names	Sell, Lnhr, Ly-22
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Lymphocyte antigen 22) (Ly-22) (Lymphocyte surface MEL-14 antigen) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

FHR4_HUMAN
NC score	0.425965 (rank : 40)	θ value	0.0113563 (rank : 50)
Query Neighborhood Hits	153	Target Neighborhood Hits	75	Shared Neighborhood Hits	54
SwissProt Accessions	Q92496, Q9UJY6	Gene names	CFHL4, FHR4
Domain Architecture
Description	Complement factor H-related protein 4 precursor (FHR-4).

LYAM1_HUMAN
NC score	0.418749 (rank : 41)	θ value	5.44631e-05 (rank : 38)
Query Neighborhood Hits	153	Target Neighborhood Hits	315	Shared Neighborhood Hits	85
SwissProt Accessions	P14151, P15023	Gene names	SELL, LNHR, LYAM1
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Leukocyte surface antigen Leu-8) (TQ1) (gp90-MEL) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

SEZ6L_HUMAN
NC score	0.399378 (rank : 42)	θ value	0.0113563 (rank : 51)
Query Neighborhood Hits	153	Target Neighborhood Hits	289	Shared Neighborhood Hits	55
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.

CO2_HUMAN
NC score	0.313255 (rank : 43)	θ value	2.21117e-06 (rank : 29)
Query Neighborhood Hits	153	Target Neighborhood Hits	258	Shared Neighborhood Hits	56
SwissProt Accessions	P06681, O19694, Q13904	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

SUSD1_HUMAN
NC score	0.285845 (rank : 44)	θ value	1.09739e-05 (rank : 33)
Query Neighborhood Hits	153	Target Neighborhood Hits	285	Shared Neighborhood Hits	82
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

CFAB_MOUSE
NC score	0.270477 (rank : 45)	θ value	0.0736092 (rank : 62)
Query Neighborhood Hits	153	Target Neighborhood Hits	262	Shared Neighborhood Hits	56
SwissProt Accessions	P04186	Gene names	Cfb, Bf, H2-Bf
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

CFAB_HUMAN
NC score	0.267251 (rank : 46)	θ value	0.0563607 (rank : 61)
Query Neighborhood Hits	153	Target Neighborhood Hits	251	Shared Neighborhood Hits	56
SwissProt Accessions	P00751, O15006, Q29944, Q96HX6, Q9BTF5, Q9BX92	Gene names	CFB, BF
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) (Properdin factor B) (Glycine-rich beta glycoprotein) (GBG) (PBF2) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

CO2_MOUSE
NC score	0.252069 (rank : 47)	θ value	0.000786445 (rank : 42)
Query Neighborhood Hits	153	Target Neighborhood Hits	250	Shared Neighborhood Hits	56
SwissProt Accessions	P21180	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

SUSD2_MOUSE
NC score	0.224462 (rank : 48)	θ value	θ > 10 (rank : 356)
Query Neighborhood Hits	153	Target Neighborhood Hits	104	Shared Neighborhood Hits	59
SwissProt Accessions	Q9DBX3, Q8BY19, Q8BYN0, Q8BYZ3, Q8BYZ9, Q8BZQ4, Q8C179	Gene names	Susd2
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 2 precursor.

SUSD2_HUMAN
NC score	0.213759 (rank : 49)	θ value	θ > 10 (rank : 355)
Query Neighborhood Hits	153	Target Neighborhood Hits	99	Shared Neighborhood Hits	56
SwissProt Accessions	Q9UGT4, Q9H5Y6	Gene names	SUSD2
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 2 precursor.

CO7_HUMAN
NC score	0.206273 (rank : 50)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	153	Target Neighborhood Hits	278	Shared Neighborhood Hits	74
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

CO6_HUMAN
NC score	0.201424 (rank : 51)	θ value	0.125558 (rank : 68)
Query Neighborhood Hits	153	Target Neighborhood Hits	331	Shared Neighborhood Hits	84
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

SUSD3_MOUSE
NC score	0.182944 (rank : 52)	θ value	θ > 10 (rank : 358)
Query Neighborhood Hits	153	Target Neighborhood Hits	39	Shared Neighborhood Hits	30
SwissProt Accessions	Q9D176, Q80XL5, Q9CYV1, Q9DA86	Gene names	Susd3
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 3.

MASP2_MOUSE
NC score	0.173412 (rank : 53)	θ value	1.43324e-05 (rank : 35)
Query Neighborhood Hits	153	Target Neighborhood Hits	382	Shared Neighborhood Hits	79
SwissProt Accessions	Q91WP0, Q9QXA4, Q9QXD2, Q9QXD5, Q9Z338	Gene names	Masp2
Domain Architecture	No domain graphic available
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

C1S_HUMAN
NC score	0.163742 (rank : 54)	θ value	5.44631e-05 (rank : 37)
Query Neighborhood Hits	153	Target Neighborhood Hits	359	Shared Neighborhood Hits	74
SwissProt Accessions	P09871, Q9UCU7, Q9UCU8, Q9UCU9, Q9UCV0, Q9UCV1, Q9UCV2, Q9UCV3, Q9UCV4, Q9UCV5, Q9UM14	Gene names	C1S
Domain Architecture
Description	Complement C1s subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s subcomponent heavy chain; Complement C1s subcomponent light chain].

MASP2_HUMAN
NC score	0.155106 (rank : 55)	θ value	0.000786445 (rank : 43)
Query Neighborhood Hits	153	Target Neighborhood Hits	364	Shared Neighborhood Hits	76
SwissProt Accessions	O00187, O75754, Q5TEQ5, Q5TER0, Q96QG4, Q9BZH0, Q9H498, Q9H499, Q9UBP3, Q9ULC7, Q9UMV3, Q9Y270	Gene names	MASP2
Domain Architecture
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

GABR1_HUMAN
NC score	0.149645 (rank : 56)	θ value	θ > 10 (rank : 219)
Query Neighborhood Hits	153	Target Neighborhood Hits	142	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UBS5, O95375, O95468, O95975, O96022, Q86W60, Q9UQQ0	Gene names	GABBR1, GPRC3A
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 1 precursor (GABA-B receptor 1) (GABA-B-R1) (Gb1).

GABR1_MOUSE
NC score	0.148732 (rank : 57)	θ value	θ > 10 (rank : 220)
Query Neighborhood Hits	153	Target Neighborhood Hits	139	Shared Neighborhood Hits	44
SwissProt Accessions	Q9WV18, Q9WU48, Q9WV15, Q9WV16, Q9WV17	Gene names	Gabbr1
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 1 precursor (GABA-B receptor 1) (GABA-B-R1) (Gb1).

CS1B_MOUSE
NC score	0.144713 (rank : 58)	θ value	0.00869519 (rank : 48)
Query Neighborhood Hits	153	Target Neighborhood Hits	361	Shared Neighborhood Hits	74
SwissProt Accessions	Q8CFG8	Gene names	C1sb, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-B subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-B subcomponent heavy chain; Complement C1s-B subcomponent light chain].

CS1A_MOUSE
NC score	0.143408 (rank : 59)	θ value	0.0431538 (rank : 59)
Query Neighborhood Hits	153	Target Neighborhood Hits	360	Shared Neighborhood Hits	74
SwissProt Accessions	Q8CG14, Q8BJC4, Q8CH28, Q8VBY4	Gene names	C1sa, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-A subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-A subcomponent heavy chain; Complement C1s-A subcomponent light chain].

KR104_HUMAN
NC score	0.142246 (rank : 60)	θ value	0.62314 (rank : 93)
Query Neighborhood Hits	153	Target Neighborhood Hits	313	Shared Neighborhood Hits	60
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

KR107_HUMAN
NC score	0.141506 (rank : 61)	θ value	0.0193708 (rank : 56)
Query Neighborhood Hits	153	Target Neighborhood Hits	330	Shared Neighborhood Hits	60
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

MASP1_HUMAN
NC score	0.141076 (rank : 62)	θ value	0.279714 (rank : 80)
Query Neighborhood Hits	153	Target Neighborhood Hits	369	Shared Neighborhood Hits	77
SwissProt Accessions	P48740, O95570, Q9UF09	Gene names	MASP1, CRARF, CRARF1, PRSS5
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) (Mannose-binding protein- associated serine protease) (MASP-1) [Contains: Complement-activating component of Ra-reactive factor heavy chain; Complement-activating component of Ra-reactive factor light chain].

MEGF6_HUMAN
NC score	0.140439 (rank : 63)	θ value	1.69304e-06 (rank : 28)
Query Neighborhood Hits	153	Target Neighborhood Hits	671	Shared Neighborhood Hits	82
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

SREC2_MOUSE
NC score	0.140030 (rank : 64)	θ value	3.19293e-05 (rank : 36)
Query Neighborhood Hits	153	Target Neighborhood Hits	605	Shared Neighborhood Hits	67
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

CUBN_HUMAN
NC score	0.136388 (rank : 65)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	153	Target Neighborhood Hits	482	Shared Neighborhood Hits	70
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

MASP1_MOUSE
NC score	0.132862 (rank : 66)	θ value	0.00869519 (rank : 49)
Query Neighborhood Hits	153	Target Neighborhood Hits	364	Shared Neighborhood Hits	76
SwissProt Accessions	P98064	Gene names	Masp1, Crarf
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) [Contains: Complement- activating component of Ra-reactive factor heavy chain; Complement- activating component of Ra-reactive factor light chain].

K0247_HUMAN
NC score	0.132486 (rank : 67)	θ value	θ > 10 (rank : 233)
Query Neighborhood Hits	153	Target Neighborhood Hits	42	Shared Neighborhood Hits	29
SwissProt Accessions	Q92537	Gene names	KIAA0247
Domain Architecture	No domain graphic available
Description	Protein KIAA0247 precursor.

KR102_HUMAN
NC score	0.131214 (rank : 68)	θ value	0.47712 (rank : 86)
Query Neighborhood Hits	153	Target Neighborhood Hits	264	Shared Neighborhood Hits	54
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

GNPTA_MOUSE
NC score	0.129654 (rank : 69)	θ value	0.0148317 (rank : 52)
Query Neighborhood Hits	153	Target Neighborhood Hits	47	Shared Neighborhood Hits	15
SwissProt Accessions	Q69ZN6, Q3U3K6, Q3US34	Gene names	Gnptab, Gnpta, Kiaa1208
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphotransferase subunits alpha/beta precursor (EC 2.7.8.17) (GlcNAc-1-phosphotransferase alpha/beta subunits) (UDP- N-acetylglucosamine-1-phosphotransferase alpha/beta subunits) (Stealth protein GNPTAB) [Contains: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta].

CUBN_MOUSE
NC score	0.129268 (rank : 70)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	153	Target Neighborhood Hits	477	Shared Neighborhood Hits	72
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

KR109_HUMAN
NC score	0.128366 (rank : 71)	θ value	0.21417 (rank : 75)
Query Neighborhood Hits	153	Target Neighborhood Hits	226	Shared Neighborhood Hits	47
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

KR101_HUMAN
NC score	0.127169 (rank : 72)	θ value	5.27518 (rank : 131)
Query Neighborhood Hits	153	Target Neighborhood Hits	261	Shared Neighborhood Hits	52
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

KR106_HUMAN
NC score	0.126259 (rank : 73)	θ value	0.365318 (rank : 81)
Query Neighborhood Hits	153	Target Neighborhood Hits	347	Shared Neighborhood Hits	62
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

KR10B_HUMAN
NC score	0.126031 (rank : 74)	θ value	0.125558 (rank : 69)
Query Neighborhood Hits	153	Target Neighborhood Hits	269	Shared Neighborhood Hits	51
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

GNPTA_HUMAN
NC score	0.122864 (rank : 75)	θ value	0.0431538 (rank : 60)
Query Neighborhood Hits	153	Target Neighborhood Hits	43	Shared Neighborhood Hits	16
SwissProt Accessions	Q3T906, Q3ZQK2, Q6IPW5, Q86TQ2, Q96N13, Q9ULL2	Gene names	GNPTAB, GNPTA, KIAA1208
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphotransferase subunits alpha/beta precursor (EC 2.7.8.17) (GlcNAc-1-phosphotransferase alpha/beta subunits) (UDP- N-acetylglucosamine-1-phosphotransferase alpha/beta subunits) (Stealth protein GNPTAB) [Contains: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta].

ZAN_MOUSE
NC score	0.122322 (rank : 76)	θ value	0.21417 (rank : 76)
Query Neighborhood Hits	153	Target Neighborhood Hits	808	Shared Neighborhood Hits	81
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

SREC2_HUMAN
NC score	0.122071 (rank : 77)	θ value	0.00390308 (rank : 46)
Query Neighborhood Hits	153	Target Neighborhood Hits	645	Shared Neighborhood Hits	69
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

SREC_HUMAN
NC score	0.121147 (rank : 78)	θ value	0.0148317 (rank : 54)
Query Neighborhood Hits	153	Target Neighborhood Hits	645	Shared Neighborhood Hits	69
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

PERT_MOUSE
NC score	0.120961 (rank : 79)	θ value	θ > 10 (rank : 332)
Query Neighborhood Hits	153	Target Neighborhood Hits	221	Shared Neighborhood Hits	80
SwissProt Accessions	P35419, Q8C8B1	Gene names	Tpo
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

C1R_HUMAN
NC score	0.120918 (rank : 80)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	153	Target Neighborhood Hits	364	Shared Neighborhood Hits	73
SwissProt Accessions	P00736, Q8J012	Gene names	C1R
Domain Architecture
Description	Complement C1r subcomponent precursor (EC 3.4.21.41) (Complement component 1, r subcomponent) [Contains: Complement C1r subcomponent heavy chain; Complement C1r subcomponent light chain].

C1RA_MOUSE
NC score	0.118974 (rank : 81)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	153	Target Neighborhood Hits	379	Shared Neighborhood Hits	72
SwissProt Accessions	Q8CG16, Q99KI6, Q9ET60	Gene names	C1ra, C1r
Domain Architecture
Description	Complement C1r-A subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-A subcomponent) [Contains: Complement C1r-A subcomponent heavy chain; Complement C1r-A subcomponent light chain].

C1RB_MOUSE
NC score	0.118384 (rank : 82)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	153	Target Neighborhood Hits	380	Shared Neighborhood Hits	72
SwissProt Accessions	Q8CFG9	Gene names	C1rb, C1r
Domain Architecture	No domain graphic available
Description	Complement C1r-B subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-B subcomponent) [Contains: Complement C1r-B subcomponent heavy chain; Complement C1r-B subcomponent light chain].

NOTC1_MOUSE
NC score	0.117740 (rank : 83)	θ value	0.0736092 (rank : 64)
Query Neighborhood Hits	153	Target Neighborhood Hits	916	Shared Neighborhood Hits	85
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC3_MOUSE
NC score	0.116931 (rank : 84)	θ value	0.0148317 (rank : 53)
Query Neighborhood Hits	153	Target Neighborhood Hits	975	Shared Neighborhood Hits	85
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC3_HUMAN
NC score	0.114921 (rank : 85)	θ value	0.00665767 (rank : 47)
Query Neighborhood Hits	153	Target Neighborhood Hits	1062	Shared Neighborhood Hits	85
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

CSPG3_MOUSE
NC score	0.114470 (rank : 86)	θ value	2.36792 (rank : 109)
Query Neighborhood Hits	153	Target Neighborhood Hits	657	Shared Neighborhood Hits	86
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

LTBP4_MOUSE
NC score	0.112793 (rank : 87)	θ value	0.0330416 (rank : 58)
Query Neighborhood Hits	153	Target Neighborhood Hits	607	Shared Neighborhood Hits	75
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

PERT_HUMAN
NC score	0.112524 (rank : 88)	θ value	θ > 10 (rank : 331)
Query Neighborhood Hits	153	Target Neighborhood Hits	221	Shared Neighborhood Hits	74
SwissProt Accessions	P07202, P09934, P09935, Q8IUL0, Q8NF94, Q8NF95, Q8NF96, Q8NF97, Q8TCI9	Gene names	TPO
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

KR108_HUMAN
NC score	0.112226 (rank : 89)	θ value	1.38821 (rank : 104)
Query Neighborhood Hits	153	Target Neighborhood Hits	226	Shared Neighborhood Hits	52
SwissProt Accessions	P60410	Gene names	KRTAP10-8, KAP10.8, KAP18-8, KRTAP10.8, KRTAP18-8, KRTAP18.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-8 (Keratin-associated protein 10.8) (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8).

NOTC1_HUMAN
NC score	0.111372 (rank : 90)	θ value	0.163984 (rank : 72)
Query Neighborhood Hits	153	Target Neighborhood Hits	906	Shared Neighborhood Hits	85
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

LTBP2_MOUSE
NC score	0.109642 (rank : 91)	θ value	2.36792 (rank : 111)
Query Neighborhood Hits	153	Target Neighborhood Hits	617	Shared Neighborhood Hits	76
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

NOTC2_HUMAN
NC score	0.108973 (rank : 92)	θ value	0.813845 (rank : 98)
Query Neighborhood Hits	153	Target Neighborhood Hits	1113	Shared Neighborhood Hits	84
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

CSPG3_HUMAN
NC score	0.108660 (rank : 93)	θ value	6.88961 (rank : 136)
Query Neighborhood Hits	153	Target Neighborhood Hits	676	Shared Neighborhood Hits	86
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

TLL1_MOUSE
NC score	0.108161 (rank : 94)	θ value	θ > 10 (rank : 363)
Query Neighborhood Hits	153	Target Neighborhood Hits	237	Shared Neighborhood Hits	47
SwissProt Accessions	Q62381, Q3UTT9, Q8BNP5	Gene names	Tll1, Tll
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-) (mTll).

KR10C_HUMAN
NC score	0.107943 (rank : 95)	θ value	3.0926 (rank : 117)
Query Neighborhood Hits	153	Target Neighborhood Hits	219	Shared Neighborhood Hits	50
SwissProt Accessions	P60413	Gene names	KRTAP10-12, KAP10.12, KAP18-12, KRTAP10.12, KRTAP18-12, KRTAP18.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-12 (Keratin-associated protein 10.12) (High sulfur keratin-associated protein 10.12) (Keratin-associated protein 18-12) (Keratin-associated protein 18.12).

NOTC2_MOUSE
NC score	0.107731 (rank : 96)	θ value	1.81305 (rank : 107)
Query Neighborhood Hits	153	Target Neighborhood Hits	1069	Shared Neighborhood Hits	82
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

TLL2_MOUSE
NC score	0.107431 (rank : 97)	θ value	θ > 10 (rank : 365)
Query Neighborhood Hits	153	Target Neighborhood Hits	240	Shared Neighborhood Hits	48
SwissProt Accessions	Q9WVM6	Gene names	Tll2
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

BMP1_MOUSE
NC score	0.107335 (rank : 98)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	153	Target Neighborhood Hits	236	Shared Neighborhood Hits	47
SwissProt Accessions	P98063	Gene names	Bmp1
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

LTBP2_HUMAN
NC score	0.107301 (rank : 99)	θ value	θ > 10 (rank : 296)
Query Neighborhood Hits	153	Target Neighborhood Hits	552	Shared Neighborhood Hits	81
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

NOTC4_HUMAN
NC score	0.107301 (rank : 100)	θ value	0.365318 (rank : 82)
Query Neighborhood Hits	153	Target Neighborhood Hits	905	Shared Neighborhood Hits	84
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

FBN1_HUMAN
NC score	0.107028 (rank : 101)	θ value	0.62314 (rank : 92)
Query Neighborhood Hits	153	Target Neighborhood Hits	557	Shared Neighborhood Hits	79
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

BMP1_HUMAN
NC score	0.106901 (rank : 102)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	153	Target Neighborhood Hits	233	Shared Neighborhood Hits	47
SwissProt Accessions	P13497, Q13292, Q13872, Q14874, Q99421, Q99422, Q99423, Q9UL38	Gene names	BMP1, PCOLC
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

FBN1_MOUSE
NC score	0.106738 (rank : 103)	θ value	1.06291 (rank : 100)
Query Neighborhood Hits	153	Target Neighborhood Hits	563	Shared Neighborhood Hits	78
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

TLL2_HUMAN
NC score	0.105873 (rank : 104)	θ value	θ > 10 (rank : 364)
Query Neighborhood Hits	153	Target Neighborhood Hits	241	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Y6L7, Q6PJN5, Q9UQ00	Gene names	TLL2, KIAA0932
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

TLL1_HUMAN
NC score	0.105352 (rank : 105)	θ value	θ > 10 (rank : 362)
Query Neighborhood Hits	153	Target Neighborhood Hits	236	Shared Neighborhood Hits	46
SwissProt Accessions	O43897, Q96AN3, Q9NQS4	Gene names	TLL1, TLL
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-).

NOTC4_MOUSE
NC score	0.105342 (rank : 106)	θ value	0.365318 (rank : 83)
Query Neighborhood Hits	153	Target Neighborhood Hits	872	Shared Neighborhood Hits	84
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

FBN2_MOUSE
NC score	0.104737 (rank : 107)	θ value	8.99809 (rank : 144)
Query Neighborhood Hits	153	Target Neighborhood Hits	549	Shared Neighborhood Hits	81
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

JAG1_HUMAN
NC score	0.104352 (rank : 108)	θ value	4.03905 (rank : 120)
Query Neighborhood Hits	153	Target Neighborhood Hits	514	Shared Neighborhood Hits	81
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

JAG1_MOUSE
NC score	0.104101 (rank : 109)	θ value	2.36792 (rank : 110)
Query Neighborhood Hits	153	Target Neighborhood Hits	518	Shared Neighborhood Hits	79
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

FBN2_HUMAN
NC score	0.102480 (rank : 110)	θ value	θ > 10 (rank : 215)
Query Neighborhood Hits	153	Target Neighborhood Hits	560	Shared Neighborhood Hits	77
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

SUSD3_HUMAN
NC score	0.102058 (rank : 111)	θ value	θ > 10 (rank : 357)
Query Neighborhood Hits	153	Target Neighborhood Hits	32	Shared Neighborhood Hits	23
SwissProt Accessions	Q96L08, Q49AA6, Q6UXV7	Gene names	SUSD3, UNQ9387/PRO34275
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 3.

FBN3_HUMAN
NC score	0.100913 (rank : 112)	θ value	θ > 10 (rank : 216)
Query Neighborhood Hits	153	Target Neighborhood Hits	543	Shared Neighborhood Hits	76
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

FBLN1_MOUSE
NC score	0.100359 (rank : 113)	θ value	0.0736092 (rank : 63)
Query Neighborhood Hits	153	Target Neighborhood Hits	329	Shared Neighborhood Hits	63
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

LTBP3_MOUSE
NC score	0.100145 (rank : 114)	θ value	4.03905 (rank : 123)
Query Neighborhood Hits	153	Target Neighborhood Hits	475	Shared Neighborhood Hits	82
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

LTBP3_HUMAN
NC score	0.098508 (rank : 115)	θ value	θ > 10 (rank : 297)
Query Neighborhood Hits	153	Target Neighborhood Hits	502	Shared Neighborhood Hits	81
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

KR105_HUMAN
NC score	0.098430 (rank : 116)	θ value	θ > 10 (rank : 235)
Query Neighborhood Hits	153	Target Neighborhood Hits	271	Shared Neighborhood Hits	49
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

SCUB3_HUMAN
NC score	0.097628 (rank : 117)	θ value	θ > 10 (rank : 343)
Query Neighborhood Hits	153	Target Neighborhood Hits	428	Shared Neighborhood Hits	65
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

FBLN2_HUMAN
NC score	0.097264 (rank : 118)	θ value	1.38821 (rank : 103)
Query Neighborhood Hits	153	Target Neighborhood Hits	392	Shared Neighborhood Hits	67
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

FBLN2_MOUSE
NC score	0.097022 (rank : 119)	θ value	1.06291 (rank : 99)
Query Neighborhood Hits	153	Target Neighborhood Hits	505	Shared Neighborhood Hits	77
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

SCUB3_MOUSE
NC score	0.096127 (rank : 120)	θ value	θ > 10 (rank : 344)
Query Neighborhood Hits	153	Target Neighborhood Hits	442	Shared Neighborhood Hits	65
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

PCSK5_MOUSE
NC score	0.096105 (rank : 121)	θ value	2.36792 (rank : 112)
Query Neighborhood Hits	153	Target Neighborhood Hits	613	Shared Neighborhood Hits	79
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

CSPG2_MOUSE
NC score	0.095791 (rank : 122)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	153	Target Neighborhood Hits	711	Shared Neighborhood Hits	81
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

CSPG2_HUMAN
NC score	0.095636 (rank : 123)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	153	Target Neighborhood Hits	681	Shared Neighborhood Hits	81
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

KR10A_HUMAN
NC score	0.094929 (rank : 124)	θ value	3.0926 (rank : 116)
Query Neighborhood Hits	153	Target Neighborhood Hits	232	Shared Neighborhood Hits	47
SwissProt Accessions	P60014	Gene names	KRTAP10-10, KAP10.10, KAP18-10, KRTAP10.10, KRTAP18-1, KRTAP18.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-10 (Keratin-associated protein 10.10) (High sulfur keratin-associated protein 10.10) (Keratin-associated protein 18-10) (Keratin-associated protein 18.10).

DLL1_MOUSE
NC score	0.094037 (rank : 125)	θ value	0.21417 (rank : 74)
Query Neighborhood Hits	153	Target Neighborhood Hits	456	Shared Neighborhood Hits	71
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

DLL1_HUMAN
NC score	0.093994 (rank : 126)	θ value	0.279714 (rank : 78)
Query Neighborhood Hits	153	Target Neighborhood Hits	455	Shared Neighborhood Hits	69
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

FBLN1_HUMAN
NC score	0.093982 (rank : 127)	θ value	1.38821 (rank : 102)
Query Neighborhood Hits	153	Target Neighborhood Hits	324	Shared Neighborhood Hits	60
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

LTB1L_HUMAN
NC score	0.093268 (rank : 128)	θ value	0.47712 (rank : 88)
Query Neighborhood Hits	153	Target Neighborhood Hits	553	Shared Neighborhood Hits	70
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

JAG2_HUMAN
NC score	0.093021 (rank : 129)	θ value	θ > 10 (rank : 231)
Query Neighborhood Hits	153	Target Neighborhood Hits	491	Shared Neighborhood Hits	76
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

LTB1S_HUMAN
NC score	0.092924 (rank : 130)	θ value	0.47712 (rank : 89)
Query Neighborhood Hits	153	Target Neighborhood Hits	502	Shared Neighborhood Hits	67
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

JAG2_MOUSE
NC score	0.092665 (rank : 131)	θ value	θ > 10 (rank : 232)
Query Neighborhood Hits	153	Target Neighborhood Hits	504	Shared Neighborhood Hits	74
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

C1QR1_MOUSE
NC score	0.091039 (rank : 132)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	153	Target Neighborhood Hits	342	Shared Neighborhood Hits	64
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

STAB2_MOUSE
NC score	0.090213 (rank : 133)	θ value	0.365318 (rank : 85)
Query Neighborhood Hits	153	Target Neighborhood Hits	528	Shared Neighborhood Hits	71
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

ATRN_HUMAN
NC score	0.088953 (rank : 134)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	153	Target Neighborhood Hits	525	Shared Neighborhood Hits	62
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

DNER_HUMAN
NC score	0.088840 (rank : 135)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	153	Target Neighborhood Hits	460	Shared Neighborhood Hits	67
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

CRUM2_HUMAN
NC score	0.088381 (rank : 136)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	153	Target Neighborhood Hits	453	Shared Neighborhood Hits	74
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

LTB1S_MOUSE
NC score	0.088284 (rank : 137)	θ value	θ > 10 (rank : 295)
Query Neighborhood Hits	153	Target Neighborhood Hits	479	Shared Neighborhood Hits	67
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1L_MOUSE
NC score	0.088242 (rank : 138)	θ value	θ > 10 (rank : 294)
Query Neighborhood Hits	153	Target Neighborhood Hits	514	Shared Neighborhood Hits	70
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

CRUM1_HUMAN
NC score	0.087334 (rank : 139)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	153	Target Neighborhood Hits	457	Shared Neighborhood Hits	69
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

DNER_MOUSE
NC score	0.087284 (rank : 140)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	153	Target Neighborhood Hits	413	Shared Neighborhood Hits	67
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

STAB1_MOUSE
NC score	0.086787 (rank : 141)	θ value	θ > 10 (rank : 353)
Query Neighborhood Hits	153	Target Neighborhood Hits	566	Shared Neighborhood Hits	72
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

ATRN_MOUSE
NC score	0.086779 (rank : 142)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	153	Target Neighborhood Hits	519	Shared Neighborhood Hits	63
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

DLL4_MOUSE
NC score	0.086686 (rank : 143)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	153	Target Neighborhood Hits	440	Shared Neighborhood Hits	67
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

KR103_HUMAN
NC score	0.086285 (rank : 144)	θ value	θ > 10 (rank : 234)
Query Neighborhood Hits	153	Target Neighborhood Hits	212	Shared Neighborhood Hits	42
SwissProt Accessions	P60369, Q70LJ4	Gene names	KRTAP10-3, KAP10.3, KAP18-3, KRTAP10.3, KRTAP18-3, KRTAP18.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-3 (Keratin-associated protein 10.3) (High sulfur keratin-associated protein 10.3) (Keratin-associated protein 18-3) (Keratin-associated protein 18.3).

FBLN5_MOUSE
NC score	0.085914 (rank : 145)	θ value	θ > 10 (rank : 214)
Query Neighborhood Hits	153	Target Neighborhood Hits	317	Shared Neighborhood Hits	64
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

DLL3_HUMAN
NC score	0.085725 (rank : 146)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	153	Target Neighborhood Hits	419	Shared Neighborhood Hits	67
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

PCOC1_HUMAN
NC score	0.085643 (rank : 147)	θ value	θ > 10 (rank : 325)
Query Neighborhood Hits	153	Target Neighborhood Hits	146	Shared Neighborhood Hits	13
SwissProt Accessions	Q15113, O14550	Gene names	PCOLCE, PCPE1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein).

DLL4_HUMAN
NC score	0.085400 (rank : 148)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	153	Target Neighborhood Hits	435	Shared Neighborhood Hits	69
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

PGCB_HUMAN
NC score	0.084831 (rank : 149)	θ value	θ > 10 (rank : 335)
Query Neighborhood Hits	153	Target Neighborhood Hits	478	Shared Neighborhood Hits	68
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

CRUM1_MOUSE
NC score	0.084689 (rank : 150)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	153	Target Neighborhood Hits	444	Shared Neighborhood Hits	69
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

PCOC1_MOUSE
NC score	0.084588 (rank : 151)	θ value	θ > 10 (rank : 326)
Query Neighborhood Hits	153	Target Neighborhood Hits	100	Shared Neighborhood Hits	12
SwissProt Accessions	Q61398, O35113	Gene names	Pcolce, Pcpe1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein) (P14).

DLK_HUMAN
NC score	0.084549 (rank : 152)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	153	Target Neighborhood Hits	401	Shared Neighborhood Hits	69
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

C1QR1_HUMAN
NC score	0.083937 (rank : 153)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	153	Target Neighborhood Hits	493	Shared Neighborhood Hits	70
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

DLK_MOUSE
NC score	0.083677 (rank : 154)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	153	Target Neighborhood Hits	374	Shared Neighborhood Hits	62
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

STAB2_HUMAN
NC score	0.082557 (rank : 155)	θ value	θ > 10 (rank : 354)
Query Neighborhood Hits	153	Target Neighborhood Hits	534	Shared Neighborhood Hits	71
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

LAMA5_HUMAN
NC score	0.082008 (rank : 156)	θ value	1.38821 (rank : 105)
Query Neighborhood Hits	153	Target Neighborhood Hits	976	Shared Neighborhood Hits	73
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

EGFL9_HUMAN
NC score	0.081993 (rank : 157)	θ value	θ > 10 (rank : 199)
Query Neighborhood Hits	153	Target Neighborhood Hits	365	Shared Neighborhood Hits	63
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

DLL3_MOUSE
NC score	0.081858 (rank : 158)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	153	Target Neighborhood Hits	399	Shared Neighborhood Hits	62
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

EGFL9_MOUSE
NC score	0.080768 (rank : 159)	θ value	θ > 10 (rank : 200)
Query Neighborhood Hits	153	Target Neighborhood Hits	379	Shared Neighborhood Hits	63
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

KRA51_HUMAN
NC score	0.080741 (rank : 160)	θ value	θ > 10 (rank : 248)
Query Neighborhood Hits	153	Target Neighborhood Hits	288	Shared Neighborhood Hits	51
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

PROZ_MOUSE
NC score	0.080735 (rank : 161)	θ value	θ > 10 (rank : 342)
Query Neighborhood Hits	153	Target Neighborhood Hits	410	Shared Neighborhood Hits	58
SwissProt Accessions	Q9CQW3	Gene names	Proz
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

STAB1_HUMAN
NC score	0.080603 (rank : 162)	θ value	θ > 10 (rank : 352)
Query Neighborhood Hits	153	Target Neighborhood Hits	546	Shared Neighborhood Hits	70
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

NELL2_MOUSE
NC score	0.080197 (rank : 163)	θ value	θ > 10 (rank : 311)
Query Neighborhood Hits	153	Target Neighborhood Hits	436	Shared Neighborhood Hits	71
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

FBLN5_HUMAN
NC score	0.079931 (rank : 164)	θ value	θ > 10 (rank : 213)
Query Neighborhood Hits	153	Target Neighborhood Hits	329	Shared Neighborhood Hits	65
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

GRN_HUMAN
NC score	0.079918 (rank : 165)	θ value	θ > 10 (rank : 223)
Query Neighborhood Hits	153	Target Neighborhood Hits	268	Shared Neighborhood Hits	57
SwissProt Accessions	P28799, P23781, P23782, P23783, P23784, Q9BWE7, Q9UCH0	Gene names	GRN
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)].

FBLN4_HUMAN
NC score	0.079750 (rank : 166)	θ value	θ > 10 (rank : 211)
Query Neighborhood Hits	153	Target Neighborhood Hits	278	Shared Neighborhood Hits	58
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

WIF1_MOUSE
NC score	0.079656 (rank : 167)	θ value	θ > 10 (rank : 380)
Query Neighborhood Hits	153	Target Neighborhood Hits	393	Shared Neighborhood Hits	66
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

MFRP_MOUSE
NC score	0.079629 (rank : 168)	θ value	θ > 10 (rank : 307)
Query Neighborhood Hits	153	Target Neighborhood Hits	166	Shared Neighborhood Hits	15
SwissProt Accessions	Q8K480, Q8BPP4	Gene names	Mfrp
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

NAGPA_HUMAN
NC score	0.079401 (rank : 169)	θ value	4.03905 (rank : 124)
Query Neighborhood Hits	153	Target Neighborhood Hits	282	Shared Neighborhood Hits	54
SwissProt Accessions	Q9UK23, Q96EJ8	Gene names	NAGPA
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

NELL1_HUMAN
NC score	0.079372 (rank : 170)	θ value	θ > 10 (rank : 309)
Query Neighborhood Hits	153	Target Neighborhood Hits	451	Shared Neighborhood Hits	73
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

WIF1_HUMAN
NC score	0.078991 (rank : 171)	θ value	θ > 10 (rank : 379)
Query Neighborhood Hits	153	Target Neighborhood Hits	392	Shared Neighborhood Hits	68
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

TNR14_HUMAN
NC score	0.078879 (rank : 172)	θ value	0.47712 (rank : 90)
Query Neighborhood Hits	153	Target Neighborhood Hits	149	Shared Neighborhood Hits	30
SwissProt Accessions	Q92956, Q8WXR1, Q96J31, Q9UM65	Gene names	TNFRSF14, HVEA, HVEM
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 14 precursor (Herpesvirus entry mediator A) (Tumor necrosis factor receptor-like 2) (TR2).

NELL2_HUMAN
NC score	0.078783 (rank : 173)	θ value	θ > 10 (rank : 310)
Query Neighborhood Hits	153	Target Neighborhood Hits	449	Shared Neighborhood Hits	68
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

NAGPA_MOUSE
NC score	0.078763 (rank : 174)	θ value	θ > 10 (rank : 308)
Query Neighborhood Hits	153	Target Neighborhood Hits	308	Shared Neighborhood Hits	59
SwissProt Accessions	Q8BJ48, Q3UUT5, Q8CHQ8, Q9QZE6	Gene names	Nagpa
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

KRA53_HUMAN
NC score	0.078702 (rank : 175)	θ value	θ > 10 (rank : 250)
Query Neighborhood Hits	153	Target Neighborhood Hits	331	Shared Neighborhood Hits	53
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

FBLN4_MOUSE
NC score	0.078611 (rank : 176)	θ value	θ > 10 (rank : 212)
Query Neighborhood Hits	153	Target Neighborhood Hits	270	Shared Neighborhood Hits	55
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

USH2A_MOUSE
NC score	0.078050 (rank : 177)	θ value	0.0148317 (rank : 55)
Query Neighborhood Hits	153	Target Neighborhood Hits	626	Shared Neighborhood Hits	63
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

PCOC2_HUMAN
NC score	0.077334 (rank : 178)	θ value	θ > 10 (rank : 327)
Query Neighborhood Hits	153	Target Neighborhood Hits	73	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UKZ9, Q9BRH3	Gene names	PCOLCE2, PCPE2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

FBLN3_MOUSE
NC score	0.077116 (rank : 179)	θ value	θ > 10 (rank : 210)
Query Neighborhood Hits	153	Target Neighborhood Hits	279	Shared Neighborhood Hits	57
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

SSPO_MOUSE
NC score	0.077099 (rank : 180)	θ value	0.0736092 (rank : 65)
Query Neighborhood Hits	153	Target Neighborhood Hits	800	Shared Neighborhood Hits	72
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

FBLN3_HUMAN
NC score	0.077023 (rank : 181)	θ value	θ > 10 (rank : 209)
Query Neighborhood Hits	153	Target Neighborhood Hits	293	Shared Neighborhood Hits	56
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

FRAS1_MOUSE
NC score	0.076621 (rank : 182)	θ value	θ > 10 (rank : 218)
Query Neighborhood Hits	153	Target Neighborhood Hits	747	Shared Neighborhood Hits	74
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

PGCA_HUMAN
NC score	0.076544 (rank : 183)	θ value	θ > 10 (rank : 333)
Query Neighborhood Hits	153	Target Neighborhood Hits	821	Shared Neighborhood Hits	75
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

LAMC3_HUMAN
NC score	0.076341 (rank : 184)	θ value	θ > 10 (rank : 277)
Query Neighborhood Hits	153	Target Neighborhood Hits	588	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

PROS_HUMAN
NC score	0.076303 (rank : 185)	θ value	θ > 10 (rank : 339)
Query Neighborhood Hits	153	Target Neighborhood Hits	340	Shared Neighborhood Hits	61
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

PROZ_HUMAN
NC score	0.076142 (rank : 186)	θ value	θ > 10 (rank : 341)
Query Neighborhood Hits	153	Target Neighborhood Hits	422	Shared Neighborhood Hits	60
SwissProt Accessions	P22891, Q15213	Gene names	PROZ
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

PGCB_MOUSE
NC score	0.075902 (rank : 187)	θ value	θ > 10 (rank : 336)
Query Neighborhood Hits	153	Target Neighborhood Hits	459	Shared Neighborhood Hits	66
SwissProt Accessions	Q61361	Gene names	Bcan
Domain Architecture
Description	Brevican core protein precursor.

MFRP_HUMAN
NC score	0.075813 (rank : 188)	θ value	θ > 10 (rank : 306)
Query Neighborhood Hits	153	Target Neighborhood Hits	165	Shared Neighborhood Hits	17
SwissProt Accessions	Q9BY79, Q335M3, Q96DQ9	Gene names	MFRP
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

PCOC2_MOUSE
NC score	0.075510 (rank : 189)	θ value	θ > 10 (rank : 328)
Query Neighborhood Hits	153	Target Neighborhood Hits	73	Shared Neighborhood Hits	12
SwissProt Accessions	Q8R4W6, Q3V1K6, Q9CX06	Gene names	Pcolce2, Pcpe2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

TENX_HUMAN
NC score	0.075270 (rank : 190)	θ value	θ > 10 (rank : 361)
Query Neighborhood Hits	153	Target Neighborhood Hits	789	Shared Neighborhood Hits	71
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

MATN2_HUMAN
NC score	0.075031 (rank : 191)	θ value	θ > 10 (rank : 298)
Query Neighborhood Hits	153	Target Neighborhood Hits	365	Shared Neighborhood Hits	60
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

FRAS1_HUMAN
NC score	0.074970 (rank : 192)	θ value	θ > 10 (rank : 217)
Query Neighborhood Hits	153	Target Neighborhood Hits	759	Shared Neighborhood Hits	73
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

KRA13_HUMAN
NC score	0.074949 (rank : 193)	θ value	θ > 10 (rank : 243)
Query Neighborhood Hits	153	Target Neighborhood Hits	144	Shared Neighborhood Hits	43
SwissProt Accessions	Q8IUG1, Q07628, Q8IUG0, Q9BYS2	Gene names	KRTAP1-3, B2B, KAP1.2, KAP1.3, KAP1.8, KAP1.9, KRATP1.9, KRTAP1.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-3 (Keratin-associated protein 1.8) (Keratin-associated protein 1.9).

AGRIN_HUMAN
NC score	0.074920 (rank : 194)	θ value	5.27518 (rank : 130)
Query Neighborhood Hits	153	Target Neighborhood Hits	582	Shared Neighborhood Hits	71
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

KRA59_HUMAN
NC score	0.074882 (rank : 195)	θ value	θ > 10 (rank : 256)
Query Neighborhood Hits	153	Target Neighborhood Hits	310	Shared Neighborhood Hits	51
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

MEGF8_HUMAN
NC score	0.074821 (rank : 196)	θ value	8.99809 (rank : 147)
Query Neighborhood Hits	153	Target Neighborhood Hits	528	Shared Neighborhood Hits	67
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

KRA54_HUMAN
NC score	0.074288 (rank : 197)	θ value	θ > 10 (rank : 251)
Query Neighborhood Hits	153	Target Neighborhood Hits	270	Shared Neighborhood Hits	47
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

MEGF9_HUMAN
NC score	0.074176 (rank : 198)	θ value	θ > 10 (rank : 304)
Query Neighborhood Hits	153	Target Neighborhood Hits	557	Shared Neighborhood Hits	67
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

PROS_MOUSE
NC score	0.074122 (rank : 199)	θ value	θ > 10 (rank : 340)
Query Neighborhood Hits	153	Target Neighborhood Hits	330	Shared Neighborhood Hits	60
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

KRA57_HUMAN
NC score	0.073630 (rank : 200)	θ value	θ > 10 (rank : 254)
Query Neighborhood Hits	153	Target Neighborhood Hits	269	Shared Neighborhood Hits	46
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

TRBM_HUMAN
NC score	0.073587 (rank : 201)	θ value	θ > 10 (rank : 366)
Query Neighborhood Hits	153	Target Neighborhood Hits	339	Shared Neighborhood Hits	67
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

KR511_HUMAN
NC score	0.073311 (rank : 202)	θ value	θ > 10 (rank : 241)
Query Neighborhood Hits	153	Target Neighborhood Hits	231	Shared Neighborhood Hits	44
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

KRA55_HUMAN
NC score	0.073006 (rank : 203)	θ value	θ > 10 (rank : 252)
Query Neighborhood Hits	153	Target Neighborhood Hits	257	Shared Neighborhood Hits	46
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

MATN2_MOUSE
NC score	0.073006 (rank : 204)	θ value	θ > 10 (rank : 299)
Query Neighborhood Hits	153	Target Neighborhood Hits	356	Shared Neighborhood Hits	59
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

MEGF8_MOUSE
NC score	0.072937 (rank : 205)	θ value	5.27518 (rank : 132)
Query Neighborhood Hits	153	Target Neighborhood Hits	520	Shared Neighborhood Hits	61
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

TRBM_MOUSE
NC score	0.072885 (rank : 206)	θ value	θ > 10 (rank : 367)
Query Neighborhood Hits	153	Target Neighborhood Hits	361	Shared Neighborhood Hits	62
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

LAMA5_MOUSE
NC score	0.072791 (rank : 207)	θ value	θ > 10 (rank : 270)
Query Neighborhood Hits	153	Target Neighborhood Hits	828	Shared Neighborhood Hits	69
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

KRA58_HUMAN
NC score	0.072342 (rank : 208)	θ value	θ > 10 (rank : 255)
Query Neighborhood Hits	153	Target Neighborhood Hits	324	Shared Neighborhood Hits	49
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

CUZD1_HUMAN
NC score	0.072180 (rank : 209)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	153	Target Neighborhood Hits	89	Shared Neighborhood Hits	12
SwissProt Accessions	Q86UP6, Q7Z660, Q7Z661, Q86SG1, Q86UP5, Q9HAR7	Gene names	CUZD1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Transmembrane protein UO-44).

GRN_MOUSE
NC score	0.072064 (rank : 210)	θ value	θ > 10 (rank : 224)
Query Neighborhood Hits	153	Target Neighborhood Hits	248	Shared Neighborhood Hits	53
SwissProt Accessions	P28798	Gene names	Grn
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) (PC cell-derived growth factor) (PCDGF) [Contains: Acrogranin; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7].

LAMC3_MOUSE
NC score	0.071617 (rank : 211)	θ value	0.47712 (rank : 87)
Query Neighborhood Hits	153	Target Neighborhood Hits	624	Shared Neighborhood Hits	68
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

KRA52_HUMAN
NC score	0.071459 (rank : 212)	θ value	θ > 10 (rank : 249)
Query Neighborhood Hits	153	Target Neighborhood Hits	236	Shared Neighborhood Hits	45
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

TENA_HUMAN
NC score	0.071334 (rank : 213)	θ value	θ > 10 (rank : 359)
Query Neighborhood Hits	153	Target Neighborhood Hits	631	Shared Neighborhood Hits	68
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

TENA_MOUSE
NC score	0.071273 (rank : 214)	θ value	θ > 10 (rank : 360)
Query Neighborhood Hits	153	Target Neighborhood Hits	596	Shared Neighborhood Hits	68
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

TSG6_MOUSE
NC score	0.070497 (rank : 215)	θ value	θ > 10 (rank : 369)
Query Neighborhood Hits	153	Target Neighborhood Hits	91	Shared Neighborhood Hits	15
SwissProt Accessions	O08859	Gene names	Tnfaip6, Tnfip6, Tsg6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein).

EMR1_HUMAN
NC score	0.070419 (rank : 216)	θ value	θ > 10 (rank : 203)
Query Neighborhood Hits	153	Target Neighborhood Hits	382	Shared Neighborhood Hits	63
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

TSG6_HUMAN
NC score	0.070188 (rank : 217)	θ value	θ > 10 (rank : 368)
Query Neighborhood Hits	153	Target Neighborhood Hits	91	Shared Neighborhood Hits	15
SwissProt Accessions	P98066, Q8WWI9	Gene names	TNFAIP6, TSG6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein) (Hyaluronate-binding protein).

EGFL8_MOUSE
NC score	0.069890 (rank : 218)	θ value	θ > 10 (rank : 198)
Query Neighborhood Hits	153	Target Neighborhood Hits	266	Shared Neighborhood Hits	48
SwissProt Accessions	Q6GUQ1, O35447	Gene names	Egfl8, Ng3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8).

PDGFD_HUMAN
NC score	0.069560 (rank : 219)	θ value	θ > 10 (rank : 329)
Query Neighborhood Hits	153	Target Neighborhood Hits	74	Shared Neighborhood Hits	12
SwissProt Accessions	Q9GZP0, Q9BWV5	Gene names	PDGFD, IEGF, SCDGFB
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor D precursor (PDGF D) (Iris-expressed growth factor) (Spinal cord-derived growth factor B) (SCDGF-B).

PDGFD_MOUSE
NC score	0.069339 (rank : 220)	θ value	θ > 10 (rank : 330)
Query Neighborhood Hits	153	Target Neighborhood Hits	72	Shared Neighborhood Hits	11
SwissProt Accessions	Q925I7, Q3URF6, Q8K2L3, Q9D1L8	Gene names	Pdgfd, Scdgfb
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor chain precursor (PDGF D) (Spinal cord- derived growth factor B) (SCDGF-B).

LRP12_HUMAN
NC score	0.069061 (rank : 221)	θ value	θ > 10 (rank : 287)
Query Neighborhood Hits	153	Target Neighborhood Hits	205	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y561	Gene names	LRP12, ST7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor (Suppressor of tumorigenicity protein 7).

EMR2_HUMAN
NC score	0.069025 (rank : 222)	θ value	θ > 10 (rank : 205)
Query Neighborhood Hits	153	Target Neighborhood Hits	345	Shared Neighborhood Hits	62
SwissProt Accessions	Q9UHX3, Q8NG96, Q9Y4B1	Gene names	EMR2
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen).

NRP2_MOUSE
NC score	0.068813 (rank : 223)	θ value	θ > 10 (rank : 324)
Query Neighborhood Hits	153	Target Neighborhood Hits	113	Shared Neighborhood Hits	14
SwissProt Accessions	O35375, O35373, O35374, O35376, O35377, O35378	Gene names	Nrp2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

LRP12_MOUSE
NC score	0.068395 (rank : 224)	θ value	θ > 10 (rank : 288)
Query Neighborhood Hits	153	Target Neighborhood Hits	180	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BUJ9, Q8BWM9	Gene names	Lrp12
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor.

NRP2_HUMAN
NC score	0.068306 (rank : 225)	θ value	θ > 10 (rank : 323)
Query Neighborhood Hits	153	Target Neighborhood Hits	120	Shared Neighborhood Hits	14
SwissProt Accessions	O60462, O14820, O14821	Gene names	NRP2, VEGF165R2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

GAS6_HUMAN
NC score	0.067993 (rank : 226)	θ value	θ > 10 (rank : 221)
Query Neighborhood Hits	153	Target Neighborhood Hits	348	Shared Neighborhood Hits	57
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

CD97_HUMAN
NC score	0.067931 (rank : 227)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	153	Target Neighborhood Hits	353	Shared Neighborhood Hits	62
SwissProt Accessions	P48960, O00718, O76101, Q8NG72, Q8TBQ7	Gene names	CD97
Domain Architecture
Description	CD97 antigen precursor (Leukocyte antigen CD97).

UROM_HUMAN
NC score	0.067781 (rank : 228)	θ value	θ > 10 (rank : 375)
Query Neighborhood Hits	153	Target Neighborhood Hits	284	Shared Neighborhood Hits	53
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

CUZD1_MOUSE
NC score	0.067340 (rank : 229)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	153	Target Neighborhood Hits	91	Shared Neighborhood Hits	12
SwissProt Accessions	P70412, Q9CTZ7	Gene names	Cuzd1, Itmap1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Integral membrane-associated protein 1).

CRIM1_HUMAN
NC score	0.066953 (rank : 230)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	153	Target Neighborhood Hits	362	Shared Neighborhood Hits	58
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

PGCA_MOUSE
NC score	0.066892 (rank : 231)	θ value	θ > 10 (rank : 334)
Query Neighborhood Hits	153	Target Neighborhood Hits	643	Shared Neighborhood Hits	44
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

LRP2_HUMAN
NC score	0.066688 (rank : 232)	θ value	4.03905 (rank : 122)
Query Neighborhood Hits	153	Target Neighborhood Hits	573	Shared Neighborhood Hits	74
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

KR510_HUMAN
NC score	0.066613 (rank : 233)	θ value	θ > 10 (rank : 240)
Query Neighborhood Hits	153	Target Neighborhood Hits	217	Shared Neighborhood Hits	41
SwissProt Accessions	Q6L8G5	Gene names	KRTAP5-10, KAP5.10, KRTAP5.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-10 (Keratin-associated protein 5.10) (Ultrahigh sulfur keratin-associated protein 5.10).

EGFL8_HUMAN
NC score	0.065862 (rank : 234)	θ value	θ > 10 (rank : 197)
Query Neighborhood Hits	153	Target Neighborhood Hits	270	Shared Neighborhood Hits	47
SwissProt Accessions	Q99944, Q8IV30	Gene names	EGFL8, C6orf8, NG3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8) (Vascular endothelial-statin 2) (VE-statin-2).

LCE1B_HUMAN
NC score	0.065536 (rank : 235)	θ value	θ > 10 (rank : 278)
Query Neighborhood Hits	153	Target Neighborhood Hits	58	Shared Neighborhood Hits	18
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

EMR1_MOUSE
NC score	0.065500 (rank : 236)	θ value	θ > 10 (rank : 204)
Query Neighborhood Hits	153	Target Neighborhood Hits	349	Shared Neighborhood Hits	58
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

UROM_MOUSE
NC score	0.064975 (rank : 237)	θ value	θ > 10 (rank : 376)
Query Neighborhood Hits	153	Target Neighborhood Hits	276	Shared Neighborhood Hits	51
SwissProt Accessions	Q91X17, Q3TN64, Q3TP60, Q62285	Gene names	Umod
Domain Architecture	No domain graphic available
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

LAMB2_MOUSE
NC score	0.064843 (rank : 238)	θ value	θ > 10 (rank : 273)
Query Neighborhood Hits	153	Target Neighborhood Hits	722	Shared Neighborhood Hits	64
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

LCE1C_HUMAN
NC score	0.064763 (rank : 239)	θ value	θ > 10 (rank : 279)
Query Neighborhood Hits	153	Target Neighborhood Hits	65	Shared Neighborhood Hits	18
SwissProt Accessions	Q5T751	Gene names	LCE1C, LEP3
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1C (Late envelope protein 3).

GAS6_MOUSE
NC score	0.064435 (rank : 240)	θ value	θ > 10 (rank : 222)
Query Neighborhood Hits	153	Target Neighborhood Hits	343	Shared Neighborhood Hits	60
SwissProt Accessions	Q61592, Q99K57	Gene names	Gas6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

DCBD1_MOUSE
NC score	0.064400 (rank : 241)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	153	Target Neighborhood Hits	89	Shared Neighborhood Hits	12
SwissProt Accessions	Q9D4J3, Q8R327, Q9D696	Gene names	Dcbld1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

NID1_HUMAN
NC score	0.064360 (rank : 242)	θ value	θ > 10 (rank : 317)
Query Neighborhood Hits	153	Target Neighborhood Hits	329	Shared Neighborhood Hits	62
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

KR171_HUMAN
NC score	0.063672 (rank : 243)	θ value	θ > 10 (rank : 236)
Query Neighborhood Hits	153	Target Neighborhood Hits	144	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BYP8	Gene names	KRTAP17-1, KAP17.1, KRTAP16.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 17-1 (Keratin-associated protein 16.1).

IL2RA_HUMAN
NC score	0.063608 (rank : 244)	θ value	θ > 10 (rank : 230)
Query Neighborhood Hits	153	Target Neighborhood Hits	32	Shared Neighborhood Hits	18
SwissProt Accessions	P01589	Gene names	IL2RA
Domain Architecture
Description	Interleukin-2 receptor alpha chain precursor (IL-2 receptor alpha subunit) (IL-2-RA) (IL2-RA) (p55) (TAC antigen) (CD25 antigen).

CREL1_HUMAN
NC score	0.063453 (rank : 245)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	153	Target Neighborhood Hits	441	Shared Neighborhood Hits	50
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

LAMB2_HUMAN
NC score	0.063243 (rank : 246)	θ value	8.99809 (rank : 146)
Query Neighborhood Hits	153	Target Neighborhood Hits	692	Shared Neighborhood Hits	62
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

CREL1_MOUSE
NC score	0.063216 (rank : 247)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	153	Target Neighborhood Hits	524	Shared Neighborhood Hits	50
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

USH2A_HUMAN
NC score	0.063155 (rank : 248)	θ value	θ > 10 (rank : 377)
Query Neighborhood Hits	153	Target Neighborhood Hits	600	Shared Neighborhood Hits	59
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

EGFL7_HUMAN
NC score	0.062896 (rank : 249)	θ value	θ > 10 (rank : 195)
Query Neighborhood Hits	153	Target Neighborhood Hits	325	Shared Neighborhood Hits	54
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

KRA56_HUMAN
NC score	0.062722 (rank : 250)	θ value	θ > 10 (rank : 253)
Query Neighborhood Hits	153	Target Neighborhood Hits	207	Shared Neighborhood Hits	41
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

DMBT1_MOUSE
NC score	0.062398 (rank : 251)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	153	Target Neighborhood Hits	134	Shared Neighborhood Hits	12
SwissProt Accessions	Q60997, Q80YC6, Q9JMJ9	Gene names	Dmbt1, Crpd
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (CRP-ductin) (Vomeroglandin).

EGF_MOUSE
NC score	0.062381 (rank : 252)	θ value	θ > 10 (rank : 202)
Query Neighborhood Hits	153	Target Neighborhood Hits	358	Shared Neighborhood Hits	60
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

KRA44_HUMAN
NC score	0.062253 (rank : 253)	θ value	θ > 10 (rank : 245)
Query Neighborhood Hits	153	Target Neighborhood Hits	162	Shared Neighborhood Hits	43
SwissProt Accessions	Q9BYR3	Gene names	KRTAP4-4, KAP4.4, KRTAP4.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-4 (Keratin-associated protein 4.4) (Ultrahigh sulfur keratin-associated protein 4.4).

NETO1_MOUSE
NC score	0.062210 (rank : 254)	θ value	θ > 10 (rank : 313)
Query Neighborhood Hits	153	Target Neighborhood Hits	109	Shared Neighborhood Hits	15
SwissProt Accessions	Q8R4I7, Q80X39, Q8C4S3, Q8CCM2	Gene names	Neto1, Btcl1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

NRP1_MOUSE
NC score	0.062207 (rank : 255)	θ value	θ > 10 (rank : 322)
Query Neighborhood Hits	153	Target Neighborhood Hits	120	Shared Neighborhood Hits	13
SwissProt Accessions	P97333	Gene names	Nrp1, Nrp
Domain Architecture
Description	Neuropilin-1 precursor (A5 protein).

EGFL7_MOUSE
NC score	0.062141 (rank : 256)	θ value	θ > 10 (rank : 196)
Query Neighborhood Hits	153	Target Neighborhood Hits	287	Shared Neighborhood Hits	50
SwissProt Accessions	Q9QXT5, Q6XD35, Q9DCP5	Gene names	Egfl7, Megf7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (Zneu1).

NFX1_HUMAN
NC score	0.062088 (rank : 257)	θ value	θ > 10 (rank : 316)
Query Neighborhood Hits	153	Target Neighborhood Hits	405	Shared Neighborhood Hits	49
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

LAMA2_HUMAN
NC score	0.061966 (rank : 258)	θ value	θ > 10 (rank : 268)
Query Neighborhood Hits	153	Target Neighborhood Hits	1092	Shared Neighborhood Hits	73
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

NETO1_HUMAN
NC score	0.061936 (rank : 259)	θ value	θ > 10 (rank : 312)
Query Neighborhood Hits	153	Target Neighborhood Hits	110	Shared Neighborhood Hits	15
SwissProt Accessions	Q8TDF5, Q86W85, Q8ND78, Q8TDF4	Gene names	NETO1, BTCL1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

LCE1E_HUMAN
NC score	0.061678 (rank : 260)	θ value	θ > 10 (rank : 281)
Query Neighborhood Hits	153	Target Neighborhood Hits	53	Shared Neighborhood Hits	14
SwissProt Accessions	Q5T753	Gene names	LCE1E, LEP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1E (Late envelope protein 5).

HHIP_HUMAN
NC score	0.061313 (rank : 261)	θ value	θ > 10 (rank : 226)
Query Neighborhood Hits	153	Target Neighborhood Hits	249	Shared Neighborhood Hits	53
SwissProt Accessions	Q96QV1, Q6PK09, Q8NCI7, Q9BXK3, Q9H1J4, Q9H7E7	Gene names	HHIP, HIP
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

NID2_MOUSE
NC score	0.061305 (rank : 262)	θ value	θ > 10 (rank : 320)
Query Neighborhood Hits	153	Target Neighborhood Hits	338	Shared Neighborhood Hits	56
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

KRA11_HUMAN
NC score	0.061206 (rank : 263)	θ value	θ > 10 (rank : 242)
Query Neighborhood Hits	153	Target Neighborhood Hits	155	Shared Neighborhood Hits	42
SwissProt Accessions	Q07627, Q96S60, Q96S67	Gene names	KRTAP1-1, B2A, KAP1.1, KAP1.6, KAP1.7, KRTAP1.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-1 (Keratin-associated protein 1.1) (High sulfur keratin-associated protein 1.1) (Keratin-associated protein 1.6) (Keratin-associated protein 1.7).

NETO2_HUMAN
NC score	0.061193 (rank : 264)	θ value	θ > 10 (rank : 314)
Query Neighborhood Hits	153	Target Neighborhood Hits	109	Shared Neighborhood Hits	15
SwissProt Accessions	Q8NC67, Q7Z381, Q8ND51, Q96SP4, Q9NVY8	Gene names	NETO2, BTCL2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

NRP1_HUMAN
NC score	0.061145 (rank : 265)	θ value	θ > 10 (rank : 321)
Query Neighborhood Hits	153	Target Neighborhood Hits	119	Shared Neighborhood Hits	14
SwissProt Accessions	O14786, O60461, Q96IH5	Gene names	NRP1, NRP, VEGF165R
Domain Architecture
Description	Neuropilin-1 precursor (Vascular endothelial cell growth factor 165 receptor) (CD304 antigen).

NETO2_MOUSE
NC score	0.061009 (rank : 266)	θ value	θ > 10 (rank : 315)
Query Neighborhood Hits	153	Target Neighborhood Hits	113	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BNJ6, Q5VM49, Q8C4Q8	Gene names	Neto2, Btcl2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

NID1_MOUSE
NC score	0.060917 (rank : 267)	θ value	θ > 10 (rank : 318)
Query Neighborhood Hits	153	Target Neighborhood Hits	335	Shared Neighborhood Hits	58
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

LAMA1_MOUSE
NC score	0.060537 (rank : 268)	θ value	θ > 10 (rank : 267)
Query Neighborhood Hits	153	Target Neighborhood Hits	838	Shared Neighborhood Hits	68
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

KRA45_HUMAN
NC score	0.060397 (rank : 269)	θ value	θ > 10 (rank : 246)
Query Neighborhood Hits	153	Target Neighborhood Hits	194	Shared Neighborhood Hits	45
SwissProt Accessions	Q9BYR2	Gene names	KRTAP4-5, KAP4.5, KRTAP4.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-5 (Keratin-associated protein 4.5) (Ultrahigh sulfur keratin-associated protein 4.5).

CD248_MOUSE
NC score	0.059796 (rank : 270)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	153	Target Neighborhood Hits	578	Shared Neighborhood Hits	57
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

MATN4_HUMAN
NC score	0.059744 (rank : 271)	θ value	θ > 10 (rank : 302)
Query Neighborhood Hits	153	Target Neighborhood Hits	287	Shared Neighborhood Hits	56
SwissProt Accessions	O95460, Q5QPU2, Q5QPU3, Q5QPU4, Q8N2M5, Q8N2M7, Q9H1F8, Q9H1F9	Gene names	MATN4
Domain Architecture
Description	Matrilin-4 precursor.

CMGA_MOUSE
NC score	0.059578 (rank : 272)	θ value	0.279714 (rank : 77)
Query Neighborhood Hits	153	Target Neighborhood Hits	172	Shared Neighborhood Hits	3
SwissProt Accessions	P26339	Gene names	Chga
Domain Architecture
Description	Chromogranin A precursor (CgA) [Contains: Pancreastatin; Beta-granin; WE-14].

NID2_HUMAN
NC score	0.059570 (rank : 273)	θ value	θ > 10 (rank : 319)
Query Neighborhood Hits	153	Target Neighborhood Hits	456	Shared Neighborhood Hits	58
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

KRA47_HUMAN
NC score	0.059365 (rank : 274)	θ value	θ > 10 (rank : 247)
Query Neighborhood Hits	153	Target Neighborhood Hits	204	Shared Neighborhood Hits	44
SwissProt Accessions	Q9BYR0	Gene names	KRTAP4-7, KAP4.7, KRTAP4.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-7 (Keratin-associated protein 4.7) (Ultrahigh sulfur keratin-associated protein 4.7).

MEGF9_MOUSE
NC score	0.059280 (rank : 275)	θ value	θ > 10 (rank : 305)
Query Neighborhood Hits	153	Target Neighborhood Hits	896	Shared Neighborhood Hits	63
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

LRP1_HUMAN
NC score	0.059094 (rank : 276)	θ value	θ > 10 (rank : 291)
Query Neighborhood Hits	153	Target Neighborhood Hits	617	Shared Neighborhood Hits	74
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

LRP1B_MOUSE
NC score	0.059074 (rank : 277)	θ value	θ > 10 (rank : 290)
Query Neighborhood Hits	153	Target Neighborhood Hits	606	Shared Neighborhood Hits	75
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

VWF_HUMAN
NC score	0.058985 (rank : 278)	θ value	1.06291 (rank : 101)
Query Neighborhood Hits	153	Target Neighborhood Hits	396	Shared Neighborhood Hits	57
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

EGF_HUMAN
NC score	0.058933 (rank : 279)	θ value	θ > 10 (rank : 201)
Query Neighborhood Hits	153	Target Neighborhood Hits	343	Shared Neighborhood Hits	58
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

EDIL3_MOUSE
NC score	0.058910 (rank : 280)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	153	Target Neighborhood Hits	317	Shared Neighborhood Hits	55
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

LCE1D_HUMAN
NC score	0.058804 (rank : 281)	θ value	θ > 10 (rank : 280)
Query Neighborhood Hits	153	Target Neighborhood Hits	44	Shared Neighborhood Hits	12
SwissProt Accessions	Q5T752	Gene names	LCE1D, LEP4
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1D (Late envelope protein 4).

FA10_HUMAN
NC score	0.058661 (rank : 282)	θ value	θ > 10 (rank : 206)
Query Neighborhood Hits	153	Target Neighborhood Hits	431	Shared Neighborhood Hits	56
SwissProt Accessions	P00742, Q14340	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) (Stuart- Prower factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

TSP4_HUMAN
NC score	0.058458 (rank : 283)	θ value	θ > 10 (rank : 373)
Query Neighborhood Hits	153	Target Neighborhood Hits	277	Shared Neighborhood Hits	48
SwissProt Accessions	P35443, Q86TG2	Gene names	THBS4, TSP4
Domain Architecture
Description	Thrombospondin-4 precursor.

LCE1F_HUMAN
NC score	0.058426 (rank : 284)	θ value	θ > 10 (rank : 282)
Query Neighborhood Hits	153	Target Neighborhood Hits	48	Shared Neighborhood Hits	14
SwissProt Accessions	Q5T754	Gene names	LCE1F, LEP6
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1F (Late envelope protein 6).

KR410_HUMAN
NC score	0.058416 (rank : 285)	θ value	θ > 10 (rank : 237)
Query Neighborhood Hits	153	Target Neighborhood Hits	156	Shared Neighborhood Hits	41
SwissProt Accessions	Q9BYQ7	Gene names	KRTAP4-10, KAP4.10, KRTAP4.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-10 (Keratin-associated protein 4.10) (Ultrahigh sulfur keratin-associated protein 4.10).

LRP1B_HUMAN
NC score	0.058388 (rank : 286)	θ value	θ > 10 (rank : 289)
Query Neighborhood Hits	153	Target Neighborhood Hits	602	Shared Neighborhood Hits	75
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

KRA93_HUMAN
NC score	0.058322 (rank : 287)	θ value	θ > 10 (rank : 258)
Query Neighborhood Hits	153	Target Neighborhood Hits	203	Shared Neighborhood Hits	44
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

LAMB1_MOUSE
NC score	0.058248 (rank : 288)	θ value	θ > 10 (rank : 272)
Query Neighborhood Hits	153	Target Neighborhood Hits	919	Shared Neighborhood Hits	63
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

FA10_MOUSE
NC score	0.058222 (rank : 289)	θ value	θ > 10 (rank : 207)
Query Neighborhood Hits	153	Target Neighborhood Hits	435	Shared Neighborhood Hits	60
SwissProt Accessions	O88947, O54740, Q99L32	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

KRA24_HUMAN
NC score	0.058173 (rank : 290)	θ value	4.03905 (rank : 121)
Query Neighborhood Hits	153	Target Neighborhood Hits	192	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BYR9, Q495J2	Gene names	KRTAP2-4, KAP2.4, KRTAP2.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 2-4 (Keratin-associated protein 2.4) (High sulfur keratin-associated protein 2.4).

EDIL3_HUMAN
NC score	0.058009 (rank : 291)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	153	Target Neighborhood Hits	292	Shared Neighborhood Hits	55
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

LDLR_HUMAN
NC score	0.057988 (rank : 292)	θ value	θ > 10 (rank : 285)
Query Neighborhood Hits	153	Target Neighborhood Hits	375	Shared Neighborhood Hits	63
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

KREM1_MOUSE
NC score	0.057935 (rank : 293)	θ value	θ > 10 (rank : 263)
Query Neighborhood Hits	153	Target Neighborhood Hits	92	Shared Neighborhood Hits	13
SwissProt Accessions	Q99N43	Gene names	Kremen1, Kremen
Domain Architecture
Description	Kremen protein 1 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 1) (Dickkopf receptor).

KRA98_HUMAN
NC score	0.057865 (rank : 294)	θ value	θ > 10 (rank : 260)
Query Neighborhood Hits	153	Target Neighborhood Hits	185	Shared Neighborhood Hits	41
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

LAMA1_HUMAN
NC score	0.057539 (rank : 295)	θ value	θ > 10 (rank : 266)
Query Neighborhood Hits	153	Target Neighborhood Hits	804	Shared Neighborhood Hits	62
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

KREM2_HUMAN
NC score	0.057150 (rank : 296)	θ value	θ > 10 (rank : 264)
Query Neighborhood Hits	153	Target Neighborhood Hits	93	Shared Neighborhood Hits	12
SwissProt Accessions	Q8NCW0, Q8N2J4, Q8NCW1, Q96GL8, Q9BTP9	Gene names	KREMEN2, KRM2
Domain Architecture
Description	Kremen protein 2 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 2) (Dickkopf receptor 2).

ZAN_HUMAN
NC score	0.056886 (rank : 297)	θ value	θ > 10 (rank : 381)
Query Neighborhood Hits	153	Target Neighborhood Hits	679	Shared Neighborhood Hits	65
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

HPT_HUMAN
NC score	0.056802 (rank : 298)	θ value	θ > 10 (rank : 229)
Query Neighborhood Hits	153	Target Neighborhood Hits	184	Shared Neighborhood Hits	29
SwissProt Accessions	P00738, P00737, Q2PP15, Q3B7J0, Q6LBY9	Gene names	HP
Domain Architecture
Description	Haptoglobin precursor [Contains: Haptoglobin alpha chain; Haptoglobin beta chain].

KR412_HUMAN
NC score	0.056704 (rank : 299)	θ value	θ > 10 (rank : 238)
Query Neighborhood Hits	153	Target Neighborhood Hits	178	Shared Neighborhood Hits	41
SwissProt Accessions	Q9BQ66, Q495I0	Gene names	KRTAP4-12, KAP4.12, KRTAP4.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12).

TSP4_MOUSE
NC score	0.056344 (rank : 300)	θ value	θ > 10 (rank : 374)
Query Neighborhood Hits	153	Target Neighborhood Hits	276	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Z1T2, Q9QYS3, Q9WUE0	Gene names	Thbs4, Tsp4
Domain Architecture
Description	Thrombospondin-4 precursor.

PROC_MOUSE
NC score	0.056246 (rank : 301)	θ value	θ > 10 (rank : 338)
Query Neighborhood Hits	153	Target Neighborhood Hits	426	Shared Neighborhood Hits	59
SwissProt Accessions	P33587, O35498, Q91WN8, Q99PC6	Gene names	Proc
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

LAMB1_HUMAN
NC score	0.056123 (rank : 302)	θ value	θ > 10 (rank : 271)
Query Neighborhood Hits	153	Target Neighborhood Hits	1018	Shared Neighborhood Hits	64
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

CD248_HUMAN
NC score	0.055853 (rank : 303)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	153	Target Neighborhood Hits	679	Shared Neighborhood Hits	60
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

MATN4_MOUSE
NC score	0.055442 (rank : 304)	θ value	θ > 10 (rank : 303)
Query Neighborhood Hits	153	Target Neighborhood Hits	277	Shared Neighborhood Hits	56
SwissProt Accessions	O89029, O89030, Q9QWS3	Gene names	Matn4
Domain Architecture
Description	Matrilin-4 precursor (MAT-4).

LRP3_HUMAN
NC score	0.055305 (rank : 305)	θ value	θ > 10 (rank : 292)
Query Neighborhood Hits	153	Target Neighborhood Hits	280	Shared Neighborhood Hits	37
SwissProt Accessions	O75074	Gene names	LRP3
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 3 precursor (hLRp105).

SLIT1_HUMAN
NC score	0.055180 (rank : 306)	θ value	θ > 10 (rank : 345)
Query Neighborhood Hits	153	Target Neighborhood Hits	700	Shared Neighborhood Hits	68
SwissProt Accessions	O75093, Q8WWZ2, Q9UIL7	Gene names	SLIT1, KIAA0813, MEGF4, SLIL1
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1) (Multiple epidermal growth factor-like domains 4).

KRA15_HUMAN
NC score	0.055053 (rank : 307)	θ value	θ > 10 (rank : 244)
Query Neighborhood Hits	153	Target Neighborhood Hits	126	Shared Neighborhood Hits	34
SwissProt Accessions	Q9BYS1, Q52LP6	Gene names	KRTAP1-5, KAP1.5, KRTAP1.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-5 (Keratin-associated protein 1.5) (High sulfur keratin-associated protein 1.5).

KREM1_HUMAN
NC score	0.054993 (rank : 308)	θ value	θ > 10 (rank : 262)
Query Neighborhood Hits	153	Target Neighborhood Hits	90	Shared Neighborhood Hits	12
SwissProt Accessions	Q96MU8, Q5TIB9, Q6P3X6, Q9BY70, Q9UGS5, Q9UGU1	Gene names	KREMEN1, KREMEN, KRM1
Domain Architecture
Description	Kremen protein 1 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 1) (Dickkopf receptor).

KRA94_HUMAN
NC score	0.054800 (rank : 309)	θ value	θ > 10 (rank : 259)
Query Neighborhood Hits	153	Target Neighborhood Hits	204	Shared Neighborhood Hits	47
SwissProt Accessions	Q9BYQ2	Gene names	KRTAP9-4, KAP9.4, KRTAP9.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-4 (Keratin-associated protein 9.4) (Ultrahigh sulfur keratin-associated protein 9.4).

LAMA2_MOUSE
NC score	0.054791 (rank : 310)	θ value	θ > 10 (rank : 269)
Query Neighborhood Hits	153	Target Neighborhood Hits	1198	Shared Neighborhood Hits	70
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

TSP1_HUMAN
NC score	0.054121 (rank : 311)	θ value	θ > 10 (rank : 370)
Query Neighborhood Hits	153	Target Neighborhood Hits	389	Shared Neighborhood Hits	62
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

HHIP_MOUSE
NC score	0.054090 (rank : 312)	θ value	θ > 10 (rank : 227)
Query Neighborhood Hits	153	Target Neighborhood Hits	219	Shared Neighborhood Hits	43
SwissProt Accessions	Q7TN16, Q8C0B0, Q9WU59	Gene names	Hhip, Hip
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

SLIT2_HUMAN
NC score	0.053935 (rank : 313)	θ value	θ > 10 (rank : 347)
Query Neighborhood Hits	153	Target Neighborhood Hits	708	Shared Neighborhood Hits	70
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

SLIT3_MOUSE
NC score	0.053898 (rank : 314)	θ value	θ > 10 (rank : 350)
Query Neighborhood Hits	153	Target Neighborhood Hits	700	Shared Neighborhood Hits	66
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

COMP_MOUSE
NC score	0.053272 (rank : 315)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	153	Target Neighborhood Hits	290	Shared Neighborhood Hits	47
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

HMCN1_HUMAN
NC score	0.053205 (rank : 316)	θ value	θ > 10 (rank : 228)
Query Neighborhood Hits	153	Target Neighborhood Hits	983	Shared Neighborhood Hits	75
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

KR414_HUMAN
NC score	0.053173 (rank : 317)	θ value	θ > 10 (rank : 239)
Query Neighborhood Hits	153	Target Neighborhood Hits	199	Shared Neighborhood Hits	44
SwissProt Accessions	Q9BYQ6	Gene names	KRTAP4-14, KAP4.14, KRTAP4.14
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-14 (Keratin-associated protein 4.14) (Ultrahigh sulfur keratin-associated protein 4.14).

FA9_HUMAN
NC score	0.053112 (rank : 318)	θ value	θ > 10 (rank : 208)
Query Neighborhood Hits	153	Target Neighborhood Hits	421	Shared Neighborhood Hits	55
SwissProt Accessions	P00740	Gene names	F9
Domain Architecture
Description	Coagulation factor IX precursor (EC 3.4.21.22) (Christmas factor) (Plasma thromboplastin component) (PTC) [Contains: Coagulation factor IXa light chain; Coagulation factor IXa heavy chain].

SLIT2_MOUSE
NC score	0.053085 (rank : 319)	θ value	θ > 10 (rank : 348)
Query Neighborhood Hits	153	Target Neighborhood Hits	684	Shared Neighborhood Hits	70
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

SLIT1_MOUSE
NC score	0.053000 (rank : 320)	θ value	θ > 10 (rank : 346)
Query Neighborhood Hits	153	Target Neighborhood Hits	715	Shared Neighborhood Hits	69
SwissProt Accessions	Q80TR4, Q9WVB5	Gene names	Slit1, Kiaa0813
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1).

PCSK5_HUMAN
NC score	0.052932 (rank : 321)	θ value	0.365318 (rank : 84)
Query Neighborhood Hits	153	Target Neighborhood Hits	291	Shared Neighborhood Hits	51
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).

LCE2C_HUMAN
NC score	0.052782 (rank : 322)	θ value	θ > 10 (rank : 283)
Query Neighborhood Hits	153	Target Neighborhood Hits	53	Shared Neighborhood Hits	13
SwissProt Accessions	Q5TA81	Gene names	LCE2C, LEP11
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2C (Late envelope protein 11).

HABP2_HUMAN
NC score	0.052699 (rank : 323)	θ value	θ > 10 (rank : 225)
Query Neighborhood Hits	153	Target Neighborhood Hits	431	Shared Neighborhood Hits	67
SwissProt Accessions	Q14520, O00663	Gene names	HABP2, HGFAL, PHBP
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) (Hepatocyte growth factor activator-like protein) (Factor VII-activating protease) (Factor seven-activating protease) (FSAP) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

LAMB3_MOUSE
NC score	0.052433 (rank : 324)	θ value	θ > 10 (rank : 274)
Query Neighborhood Hits	153	Target Neighborhood Hits	444	Shared Neighborhood Hits	54
SwissProt Accessions	Q61087	Gene names	Lamb3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Kalinin B1 chain).

SLIT3_HUMAN
NC score	0.052165 (rank : 325)	θ value	θ > 10 (rank : 349)
Query Neighborhood Hits	153	Target Neighborhood Hits	682	Shared Neighborhood Hits	64
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

DCBD2_HUMAN
NC score	0.052095 (rank : 326)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	153	Target Neighborhood Hits	118	Shared Neighborhood Hits	13
SwissProt Accessions	Q96PD2, Q8N6M4, Q8TDX2	Gene names	DCBLD2, CLCP1, ESDN
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein) (CUB, LCCL and coagulation factor V/VIII-homology domains protein 1).

KREM2_MOUSE
NC score	0.052081 (rank : 327)	θ value	θ > 10 (rank : 265)
Query Neighborhood Hits	153	Target Neighborhood Hits	90	Shared Neighborhood Hits	10
SwissProt Accessions	Q8K1S7	Gene names	Kremen2
Domain Architecture
Description	Kremen protein 2 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 2) (Dickkopf receptor 2).

MATN3_MOUSE
NC score	0.051751 (rank : 328)	θ value	θ > 10 (rank : 301)
Query Neighborhood Hits	153	Target Neighborhood Hits	261	Shared Neighborhood Hits	51
SwissProt Accessions	O35701, Q9JHM0	Gene names	Matn3
Domain Architecture
Description	Matrilin-3 precursor.

LRP8_MOUSE
NC score	0.051646 (rank : 329)	θ value	θ > 10 (rank : 293)
Query Neighborhood Hits	153	Target Neighborhood Hits	385	Shared Neighborhood Hits	62
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

KRA92_HUMAN
NC score	0.051602 (rank : 330)	θ value	θ > 10 (rank : 257)
Query Neighborhood Hits	153	Target Neighborhood Hits	198	Shared Neighborhood Hits	41
SwissProt Accessions	Q9BYQ4	Gene names	KRTAP9-2, KAP9.2, KRTAP9.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-2 (Keratin-associated protein 9.2) (Ultrahigh sulfur keratin-associated protein 9.2).

PROC_HUMAN
NC score	0.051553 (rank : 331)	θ value	θ > 10 (rank : 337)
Query Neighborhood Hits	153	Target Neighborhood Hits	406	Shared Neighborhood Hits	57
SwissProt Accessions	P04070, Q15189, Q15190, Q16001	Gene names	PROC
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

MATN3_HUMAN
NC score	0.051523 (rank : 332)	θ value	θ > 10 (rank : 300)
Query Neighborhood Hits	153	Target Neighborhood Hits	268	Shared Neighborhood Hits	49
SwissProt Accessions	O15232	Gene names	MATN3
Domain Architecture
Description	Matrilin-3 precursor.

DMBT1_HUMAN
NC score	0.051491 (rank : 333)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	153	Target Neighborhood Hits	152	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UGM3, Q59EX0, Q5JR26, Q6MZN4, Q96DU4, Q9UGM2, Q9UJ57, Q9UKJ4, Q9Y211, Q9Y4V9	Gene names	DMBT1, GP340
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (Glycoprotein 340) (Gp-340) (Surfactant pulmonary-associated D-binding protein).

KRA99_HUMAN
NC score	0.051458 (rank : 334)	θ value	θ > 10 (rank : 261)
Query Neighborhood Hits	153	Target Neighborhood Hits	173	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BYP9	Gene names	KRTAP9-9, KAP9.9, KRTAP9.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-9 (Keratin-associated protein 9.9) (Ultrahigh sulfur keratin-associated protein 9.9).

COMP_HUMAN
NC score	0.051155 (rank : 335)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	153	Target Neighborhood Hits	258	Shared Neighborhood Hits	46
SwissProt Accessions	P49747, O14592, Q16388, Q16389, Q8N4T2	Gene names	COMP
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

LCE3A_HUMAN
NC score	0.051013 (rank : 336)	θ value	θ > 10 (rank : 284)
Query Neighborhood Hits	153	Target Neighborhood Hits	29	Shared Neighborhood Hits	9
SwissProt Accessions	Q5TA76	Gene names	LCE3A, LEP13
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3A (Late envelope protein 13).

LAMC1_MOUSE
NC score	0.050948 (rank : 337)	θ value	θ > 10 (rank : 275)
Query Neighborhood Hits	153	Target Neighborhood Hits	856	Shared Neighborhood Hits	61
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

VLDLR_HUMAN
NC score	0.050650 (rank : 338)	θ value	θ > 10 (rank : 378)
Query Neighborhood Hits	153	Target Neighborhood Hits	383	Shared Neighborhood Hits	63
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

TSP3_MOUSE
NC score	0.050586 (rank : 339)	θ value	θ > 10 (rank : 372)
Query Neighborhood Hits	153	Target Neighborhood Hits	247	Shared Neighborhood Hits	43
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

TSP3_HUMAN
NC score	0.050316 (rank : 340)	θ value	θ > 10 (rank : 371)
Query Neighborhood Hits	153	Target Neighborhood Hits	250	Shared Neighborhood Hits	42
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

LDLR_MOUSE
NC score	0.050244 (rank : 341)	θ value	θ > 10 (rank : 286)
Query Neighborhood Hits	153	Target Neighborhood Hits	382	Shared Neighborhood Hits	62
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LAMC2_HUMAN
NC score	0.050099 (rank : 342)	θ value	θ > 10 (rank : 276)
Query Neighborhood Hits	153	Target Neighborhood Hits	715	Shared Neighborhood Hits	59
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

ST14_HUMAN
NC score	0.050054 (rank : 343)	θ value	θ > 10 (rank : 351)
Query Neighborhood Hits	153	Target Neighborhood Hits	409	Shared Neighborhood Hits	54
SwissProt Accessions	Q9Y5Y6, Q9BS01, Q9H3S0, Q9HB36, Q9HCA3	Gene names	ST14, PRSS14, SNC19, TADG15
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Matriptase) (Membrane-type serine protease 1) (MT-SP1) (Prostamin) (Serine protease TADG-15) (Tumor-associated differentially-expressed gene 15 protein).

TSP2_HUMAN
NC score	0.047980 (rank : 344)	θ value	0.47712 (rank : 91)
Query Neighborhood Hits	153	Target Neighborhood Hits	359	Shared Neighborhood Hits	58
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

CCNT2_HUMAN
NC score	0.040676 (rank : 345)	θ value	0.813845 (rank : 95)
Query Neighborhood Hits	153	Target Neighborhood Hits	84	Shared Neighborhood Hits	5
SwissProt Accessions	O60583, O60582, Q5I1Y0	Gene names	CCNT2
Domain Architecture
Description	Cyclin-T2 (CycT2).

PTX3_MOUSE
NC score	0.036679 (rank : 346)	θ value	0.0961366 (rank : 66)
Query Neighborhood Hits	153	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	P48759, Q8VDF1	Gene names	Ptx3, Tsg14
Domain Architecture
Description	Pentraxin-related protein PTX3 precursor (Pentaxin-related protein PTX3) (Tumor necrosis factor-inducible protein TSG-14).

COLQ_HUMAN
NC score	0.033688 (rank : 347)	θ value	0.21417 (rank : 73)
Query Neighborhood Hits	153	Target Neighborhood Hits	193	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y215, Q6DK18, Q6YH18, Q6YH19, Q6YH20, Q6YH21, Q9NP18, Q9NP19, Q9NP20, Q9NP21, Q9NP22, Q9NP23, Q9NP24, Q9UP88	Gene names	COLQ
Domain Architecture	No domain graphic available
Description	Acetylcholinesterase collagenic tail peptide precursor (AChE Q subunit) (Acetylcholinesterase-associated collagen).

CCNT1_HUMAN
NC score	0.030738 (rank : 348)	θ value	3.0926 (rank : 114)
Query Neighborhood Hits	153	Target Neighborhood Hits	46	Shared Neighborhood Hits	5
SwissProt Accessions	O60563, O60581	Gene names	CCNT1
Domain Architecture
Description	Cyclin-T1 (CycT1) (Cyclin-T).

CCNT1_MOUSE
NC score	0.030700 (rank : 349)	θ value	3.0926 (rank : 115)
Query Neighborhood Hits	153	Target Neighborhood Hits	58	Shared Neighborhood Hits	5
SwissProt Accessions	Q9QWV9, Q9Z0U7	Gene names	Ccnt1
Domain Architecture
Description	Cyclin-T1 (CycT1) (Cyclin-T).

PSPB_HUMAN
NC score	0.028844 (rank : 350)	θ value	8.99809 (rank : 151)
Query Neighborhood Hits	153	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	P07988, Q96R04	Gene names	SFTPB, SFTP3
Domain Architecture
Description	Pulmonary surfactant-associated protein B precursor (SP-B) (6 kDa protein) (Pulmonary surfactant-associated proteolipid SPL(Phe)) (18 kDa pulmonary-surfactant protein).

CDKN3_HUMAN
NC score	0.026744 (rank : 351)	θ value	4.03905 (rank : 119)
Query Neighborhood Hits	153	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	Q16667, Q99585, Q9BPW7, Q9BY36, Q9C042, Q9C047, Q9C049, Q9C051, Q9C053	Gene names	CDKN3, CDI1, CIP2, KAP
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 3 (EC 3.1.3.48) (EC 3.1.3.16) (CDK2- associated dual-specificity phosphatase) (Kinase-associated phosphatase) (Cyclin-dependent kinase-interacting protein 2) (Cyclin- dependent kinase interactor 1).

REXO1_MOUSE
NC score	0.025083 (rank : 352)	θ value	1.81305 (rank : 108)
Query Neighborhood Hits	153	Target Neighborhood Hits	166	Shared Neighborhood Hits	4
SwissProt Accessions	Q7TT28, Q3UMP1, Q69ZR0, Q6NSQ6, Q6PI95, Q9DA29	Gene names	Rexo1, Kiaa1138, Tceb3bp1
Domain Architecture	No domain graphic available
Description	RNA exonuclease 1 homolog (EC 3.1.-.-) (Transcription elongation factor B polypeptide 3-binding protein 1).

WISP1_MOUSE
NC score	0.024547 (rank : 353)	θ value	4.03905 (rank : 127)
Query Neighborhood Hits	153	Target Neighborhood Hits	123	Shared Neighborhood Hits	17
SwissProt Accessions	O54775, Q80ZL1	Gene names	Wisp1, Ccn4, Elm1
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (ELM-1).

GOPC_MOUSE
NC score	0.024043 (rank : 354)	θ value	0.813845 (rank : 97)
Query Neighborhood Hits	153	Target Neighborhood Hits	323	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BH60, Q8BSV4, Q920R1, Q9ET11	Gene names	Gopc
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST).

GOPC_HUMAN
NC score	0.023452 (rank : 355)	θ value	0.813845 (rank : 96)
Query Neighborhood Hits	153	Target Neighborhood Hits	377	Shared Neighborhood Hits	4
SwissProt Accessions	Q9HD26, Q59FS4, Q969U8	Gene names	GOPC, CAL, FIG
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST) (CFTR-associated ligand) (Fused in glioblastoma).

ADA33_HUMAN
NC score	0.023376 (rank : 356)	θ value	5.27518 (rank : 129)
Query Neighborhood Hits	153	Target Neighborhood Hits	264	Shared Neighborhood Hits	45
SwissProt Accessions	Q9BZ11, Q5JT75, Q5JT76, Q8N0W6	Gene names	ADAM33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

ADA33_MOUSE
NC score	0.022763 (rank : 357)	θ value	1.81305 (rank : 106)
Query Neighborhood Hits	153	Target Neighborhood Hits	231	Shared Neighborhood Hits	37
SwissProt Accessions	Q923W9	Gene names	Adam33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

WISP1_HUMAN
NC score	0.021264 (rank : 358)	θ value	8.99809 (rank : 153)
Query Neighborhood Hits	153	Target Neighborhood Hits	121	Shared Neighborhood Hits	18
SwissProt Accessions	O95388, Q9HCS3	Gene names	WISP1, CCN4
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (Wnt-1- induced secreted protein).

LIPE_HUMAN
NC score	0.020699 (rank : 359)	θ value	0.279714 (rank : 79)
Query Neighborhood Hits	153	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y5X9, Q6UW82	Gene names	LIPG
Domain Architecture
Description	Endothelial lipase precursor (EC 3.1.1.3) (Endothelial cell-derived lipase) (EDL) (EL).

ATS9_HUMAN
NC score	0.018777 (rank : 360)	θ value	3.0926 (rank : 113)
Query Neighborhood Hits	153	Target Neighborhood Hits	219	Shared Neighborhood Hits	32
SwissProt Accessions	Q9P2N4, Q9NR29	Gene names	ADAMTS9, KIAA1312
Domain Architecture
Description	ADAMTS-9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 9) (ADAM-TS 9) (ADAM-TS9).

PTPRB_HUMAN
NC score	0.015259 (rank : 361)	θ value	0.125558 (rank : 70)
Query Neighborhood Hits	153	Target Neighborhood Hits	242	Shared Neighborhood Hits	6
SwissProt Accessions	P23467	Gene names	PTPRB, PTPB
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase beta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase beta) (R-PTP-beta).

ADA21_HUMAN
NC score	0.014713 (rank : 362)	θ value	8.99809 (rank : 140)
Query Neighborhood Hits	153	Target Neighborhood Hits	181	Shared Neighborhood Hits	37
SwissProt Accessions	Q9UKJ8, O43507	Gene names	ADAM21
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21).

CDAN1_HUMAN
NC score	0.011535 (rank : 363)	θ value	8.99809 (rank : 143)
Query Neighborhood Hits	153	Target Neighborhood Hits	92	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IWY9, Q7Z7L5, Q969N3	Gene names	CDAN1
Domain Architecture	No domain graphic available
Description	Codanin-1.

VAV_MOUSE
NC score	0.010508 (rank : 364)	θ value	0.62314 (rank : 94)
Query Neighborhood Hits	153	Target Neighborhood Hits	430	Shared Neighborhood Hits	3
SwissProt Accessions	P27870, Q8BTV7	Gene names	Vav1, Vav
Domain Architecture
Description	Proto-oncogene vav (p95vav).

MMP21_HUMAN
NC score	0.009861 (rank : 365)	θ value	6.88961 (rank : 137)
Query Neighborhood Hits	153	Target Neighborhood Hits	76	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N119, Q8NG02	Gene names	MMP21
Domain Architecture	No domain graphic available
Description	Matrix metalloproteinase-21 precursor (EC 3.4.24.-) (MMP-21).

MMP21_MOUSE
NC score	0.008951 (rank : 366)	θ value	8.99809 (rank : 148)
Query Neighborhood Hits	153	Target Neighborhood Hits	59	Shared Neighborhood Hits	6
SwissProt Accessions	Q8K3F2	Gene names	Mmp21
Domain Architecture	No domain graphic available
Description	Matrix metalloproteinase-21 precursor (EC 3.4.24.-) (MMP-21).

ANM7_HUMAN
NC score	0.007917 (rank : 367)	θ value	8.99809 (rank : 141)
Query Neighborhood Hits	153	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NVM4, Q96PV5, Q9H9L0	Gene names	PRMT7, KIAA1933
Domain Architecture
Description	Protein arginine N-methyltransferase 7 (EC 2.1.1.-).

YTDC1_HUMAN
NC score	0.007549 (rank : 368)	θ value	5.27518 (rank : 135)
Query Neighborhood Hits	153	Target Neighborhood Hits	458	Shared Neighborhood Hits	2
SwissProt Accessions	Q96MU7, Q7Z622, Q8TF35	Gene names	YTHDC1, KIAA1966, YT521
Domain Architecture
Description	YTH domain-containing protein 1 (Putative splicing factor YT521).

WDR4_HUMAN
NC score	0.007210 (rank : 369)	θ value	8.99809 (rank : 152)
Query Neighborhood Hits	153	Target Neighborhood Hits	145	Shared Neighborhood Hits	2
SwissProt Accessions	P57081, Q9HCR3	Gene names	WDR4
Domain Architecture
Description	WD repeat protein 4.

POMT2_MOUSE
NC score	0.007134 (rank : 370)	θ value	8.99809 (rank : 150)
Query Neighborhood Hits	153	Target Neighborhood Hits	26	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BGQ4, Q8R4Z0	Gene names	Pomt2
Domain Architecture
Description	Protein O-mannosyl-transferase 2 (EC 2.4.1.109) (Dolichyl-phosphate- mannose--protein mannosyltransferase 2).

RX_MOUSE
NC score	0.007012 (rank : 371)	θ value	4.03905 (rank : 126)
Query Neighborhood Hits	153	Target Neighborhood Hits	429	Shared Neighborhood Hits	3
SwissProt Accessions	O35602, O08748	Gene names	Rax, Rx
Domain Architecture
Description	Retinal homeobox protein Rx (Retina and anterior neural fold homeobox protein).

PTN23_MOUSE
NC score	0.006926 (rank : 372)	θ value	4.03905 (rank : 125)
Query Neighborhood Hits	153	Target Neighborhood Hits	726	Shared Neighborhood Hits	10
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

VAV_HUMAN
NC score	0.006759 (rank : 373)	θ value	5.27518 (rank : 133)
Query Neighborhood Hits	153	Target Neighborhood Hits	452	Shared Neighborhood Hits	3
SwissProt Accessions	P15498, Q15860	Gene names	VAV1, VAV
Domain Architecture
Description	Proto-oncogene vav.

GPX5_MOUSE
NC score	0.005135 (rank : 374)	θ value	8.99809 (rank : 145)
Query Neighborhood Hits	153	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	P21765	Gene names	Gpx5
Domain Architecture
Description	Epididymal secretory glutathione peroxidase precursor (EC 1.11.1.9) (Epididymis-specific glutathione peroxidase-like protein) (EGLP) (Major androgen-regulated protein) (arMEP24).

OFD1_HUMAN
NC score	0.005022 (rank : 375)	θ value	8.99809 (rank : 149)
Query Neighborhood Hits	153	Target Neighborhood Hits	753	Shared Neighborhood Hits	4
SwissProt Accessions	O75665, O75666	Gene names	OFD1, CXorf5
Domain Architecture	No domain graphic available
Description	Oral-facial-digital syndrome 1 protein (Protein 71-7A).

PTN21_MOUSE
NC score	0.004708 (rank : 376)	θ value	6.88961 (rank : 138)
Query Neighborhood Hits	153	Target Neighborhood Hits	155	Shared Neighborhood Hits	4
SwissProt Accessions	Q62136	Gene names	Ptpn21
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-RL10).

WDFY1_HUMAN
NC score	0.004539 (rank : 377)	θ value	5.27518 (rank : 134)
Query Neighborhood Hits	153	Target Neighborhood Hits	305	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IWB7, Q9H9D5, Q9P2B3	Gene names	WDFY1, KIAA1435, WDF1, ZFYVE17
Domain Architecture	No domain graphic available
Description	WD repeat and FYVE domain-containing protein 1 (WD40- and FYVE domain- containing protein 1) (Phosphoinositide-binding protein 1) (FENS-1) (Zinc finger FYVE domain-containing protein 17).

SEM3F_MOUSE
NC score	0.002227 (rank : 378)	θ value	6.88961 (rank : 139)
Query Neighborhood Hits	153	Target Neighborhood Hits	86	Shared Neighborhood Hits	2
SwissProt Accessions	O88632, O88633	Gene names	Sema3f
Domain Architecture
Description	Semaphorin-3F precursor (Semaphorin IV) (Sema IV).

CAD13_MOUSE
NC score	-0.000443 (rank : 379)	θ value	8.99809 (rank : 142)
Query Neighborhood Hits	153	Target Neighborhood Hits	156	Shared Neighborhood Hits	2
SwissProt Accessions	Q9WTR5	Gene names	Cdh13
Domain Architecture
Description	Cadherin-13 precursor (Truncated-cadherin) (T-cadherin) (T-cad) (Heart-cadherin) (H-cadherin).

BCL6B_HUMAN
NC score	-0.002356 (rank : 380)	θ value	4.03905 (rank : 118)
Query Neighborhood Hits	153	Target Neighborhood Hits	855	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N143, Q6PCB4	Gene names	BCL6B, BAZF, ZNF62
Domain Architecture	No domain graphic available
Description	B-cell CLL/lymphoma 6 member B protein (Bcl6-associated zinc finger protein) (Zinc finger protein 62).

ZN563_HUMAN
NC score	-0.004234 (rank : 381)	θ value	4.03905 (rank : 128)
Query Neighborhood Hits	153	Target Neighborhood Hits	754	Shared Neighborhood Hits	5
SwissProt Accessions	Q8TA94, Q8NAT7	Gene names	ZNF563
Domain Architecture	No domain graphic available
Description	Zinc finger protein 563.