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Network neighborhood for query Sequence : SUSD3_HUMAN

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SUSD3_HUMAN
SwissProt Accessions	Q96L08, Q49AA6, Q6UXV7	Gene names	SUSD3, UNQ9387/PRO34275
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 3.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SUSD3_HUMAN
θ value	8.11517e-126 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	32	Target Neighborhood Hits	32	Shared Neighborhood Hits	32
SwissProt Accessions	Q96L08, Q49AA6, Q6UXV7	Gene names	SUSD3, UNQ9387/PRO34275
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 3.

SUSD3_MOUSE
θ value	1.22964e-73 (rank : 2)	NC score	0.949975 (rank : 2)
Query Neighborhood Hits	32	Target Neighborhood Hits	39	Shared Neighborhood Hits	27
SwissProt Accessions	Q9D176, Q80XL5, Q9CYV1, Q9DA86	Gene names	Susd3
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 3.

MCP_HUMAN
θ value	0.00509761 (rank : 3)	NC score	0.266934 (rank : 3)
Query Neighborhood Hits	32	Target Neighborhood Hits	82	Shared Neighborhood Hits	28
SwissProt Accessions	P15529, Q15429, Q53GV9, Q5HY94, Q5VWS6, Q5VWS7, Q5VWS8, Q5VWS9, Q5VWT0, Q5VWT1, Q5VWT2, Q6N0A1, Q7Z3R5, Q9NNW2, Q9NNW3, Q9NNW4	Gene names	CD46, MCP
Domain Architecture
Description	Membrane cofactor protein precursor (Trophoblast leukocyte common antigen) (TLX) (CD46 antigen).

CR1_HUMAN
θ value	0.00869519 (rank : 4)	NC score	0.262531 (rank : 4)
Query Neighborhood Hits	32	Target Neighborhood Hits	108	Shared Neighborhood Hits	28
SwissProt Accessions	P17927, Q16745, Q9UQV2	Gene names	CR1, C3BR
Domain Architecture
Description	Complement receptor type 1 precursor (C3b/C4b receptor) (CD35 antigen).

CSMD2_HUMAN
θ value	0.0148317 (rank : 5)	NC score	0.206754 (rank : 17)
Query Neighborhood Hits	32	Target Neighborhood Hits	188	Shared Neighborhood Hits	28
SwissProt Accessions	Q7Z408, Q5VT59, Q8N963, Q96Q03, Q9H4V7, Q9H4V8, Q9H4V9, Q9H4W0, Q9H4W1, Q9H4W2, Q9H4W3, Q9H4W4, Q9HCY5, Q9HCY6, Q9HCY7	Gene names	CSMD2, KIAA1884
Domain Architecture
Description	CUB and sushi domain-containing protein 2 (CUB and sushi multiple domains protein 2).

CSMD1_HUMAN
θ value	0.0330416 (rank : 6)	NC score	0.208364 (rank : 15)
Query Neighborhood Hits	32	Target Neighborhood Hits	176	Shared Neighborhood Hits	28
SwissProt Accessions	Q96PZ7, Q96QU9, Q96RM4	Gene names	CSMD1, KIAA1890
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

LYAM2_MOUSE
θ value	0.0563607 (rank : 7)	NC score	0.198261 (rank : 23)
Query Neighborhood Hits	32	Target Neighborhood Hits	420	Shared Neighborhood Hits	28
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

I10R2_HUMAN
θ value	0.279714 (rank : 8)	NC score	0.063140 (rank : 57)
Query Neighborhood Hits	32	Target Neighborhood Hits	43	Shared Neighborhood Hits	3
SwissProt Accessions	Q08334, Q9BUU4	Gene names	IL10RB, CRFB4
Domain Architecture
Description	Interleukin-10 receptor beta chain precursor (IL-10R-B) (IL-10R2) (Cytokine receptor family 2 member 4) (Cytokine receptor class-II member 4) (CRF2-4) (CDw210b antigen).

C4BB_HUMAN
θ value	0.365318 (rank : 9)	NC score	0.242700 (rank : 6)
Query Neighborhood Hits	32	Target Neighborhood Hits	77	Shared Neighborhood Hits	28
SwissProt Accessions	P20851	Gene names	C4BPB
Domain Architecture
Description	C4b-binding protein beta chain precursor.

CR2_HUMAN
θ value	0.365318 (rank : 10)	NC score	0.233622 (rank : 7)
Query Neighborhood Hits	32	Target Neighborhood Hits	89	Shared Neighborhood Hits	28
SwissProt Accessions	P20023, Q13866, Q14212	Gene names	CR2, C3DR
Domain Architecture
Description	Complement receptor type 2 precursor (Cr2) (Complement C3d receptor) (Epstein-Barr virus receptor) (EBV receptor) (CD21 antigen).

SEZ6L_HUMAN
θ value	0.365318 (rank : 11)	NC score	0.205014 (rank : 19)
Query Neighborhood Hits	32	Target Neighborhood Hits	289	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.

CSMD1_MOUSE
θ value	0.47712 (rank : 12)	NC score	0.200517 (rank : 22)
Query Neighborhood Hits	32	Target Neighborhood Hits	193	Shared Neighborhood Hits	28
SwissProt Accessions	Q923L3, Q8BUV1, Q8BYQ3	Gene names	Csmd1
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

CSMD3_HUMAN
θ value	0.47712 (rank : 13)	NC score	0.197911 (rank : 24)
Query Neighborhood Hits	32	Target Neighborhood Hits	199	Shared Neighborhood Hits	28
SwissProt Accessions	Q7Z407, Q96PZ3	Gene names	CSMD3, KIAA1894
Domain Architecture
Description	CUB and sushi domain-containing protein 3 precursor (CUB and sushi multiple domains protein 3).

LYAM3_MOUSE
θ value	0.47712 (rank : 14)	NC score	0.203067 (rank : 20)
Query Neighborhood Hits	32	Target Neighborhood Hits	390	Shared Neighborhood Hits	28
SwissProt Accessions	Q01102	Gene names	Selp, Grmp
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

CRRY_MOUSE
θ value	0.62314 (rank : 15)	NC score	0.244738 (rank : 5)
Query Neighborhood Hits	32	Target Neighborhood Hits	84	Shared Neighborhood Hits	28
SwissProt Accessions	Q64735, Q3TV30, Q58E68, Q61447, Q61449, Q8CF59, Q8K328	Gene names	Crry, Cry
Domain Architecture	No domain graphic available
Description	Complement regulatory protein Crry precursor (Protein p65).

SUSD2_HUMAN
θ value	0.62314 (rank : 16)	NC score	0.207697 (rank : 16)
Query Neighborhood Hits	32	Target Neighborhood Hits	99	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UGT4, Q9H5Y6	Gene names	SUSD2
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 2 precursor.

ZP3R_MOUSE
θ value	0.62314 (rank : 17)	NC score	0.229094 (rank : 9)
Query Neighborhood Hits	32	Target Neighborhood Hits	81	Shared Neighborhood Hits	27
SwissProt Accessions	Q60736	Gene names	Zp3r, Sp56
Domain Architecture
Description	Zona pellucida sperm-binding protein 3 receptor precursor (Sperm fertilization protein 56) (sp56).

CFAH_MOUSE
θ value	0.813845 (rank : 18)	NC score	0.178718 (rank : 29)
Query Neighborhood Hits	32	Target Neighborhood Hits	112	Shared Neighborhood Hits	28
SwissProt Accessions	P06909	Gene names	Cfh, Hf1
Domain Architecture
Description	Complement factor H precursor (Protein beta-1-H).

LYAM2_HUMAN
θ value	0.813845 (rank : 19)	NC score	0.190807 (rank : 26)
Query Neighborhood Hits	32	Target Neighborhood Hits	394	Shared Neighborhood Hits	28
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

SUSD2_MOUSE
θ value	0.813845 (rank : 20)	NC score	0.189135 (rank : 27)
Query Neighborhood Hits	32	Target Neighborhood Hits	104	Shared Neighborhood Hits	29
SwissProt Accessions	Q9DBX3, Q8BY19, Q8BYN0, Q8BYZ3, Q8BYZ9, Q8BZQ4, Q8C179	Gene names	Susd2
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 2 precursor.

APOH_HUMAN
θ value	1.06291 (rank : 21)	NC score	0.200793 (rank : 21)
Query Neighborhood Hits	32	Target Neighborhood Hits	75	Shared Neighborhood Hits	27
SwissProt Accessions	P02749, Q9UCN7	Gene names	APOH, B2G1
Domain Architecture
Description	Beta-2-glycoprotein 1 precursor (Beta-2-glycoprotein I) (Apolipoprotein H) (Apo-H) (B2GPI) (Beta(2)GPI) (Activated protein C- binding protein) (APC inhibitor) (Anticardiolipin cofactor).

C4BP_MOUSE
θ value	1.06291 (rank : 22)	NC score	0.231717 (rank : 8)
Query Neighborhood Hits	32	Target Neighborhood Hits	91	Shared Neighborhood Hits	28
SwissProt Accessions	P08607	Gene names	C4bpa, C4bp
Domain Architecture
Description	C4b-binding protein precursor (C4bp).

DAF2_MOUSE
θ value	1.06291 (rank : 23)	NC score	0.223622 (rank : 11)
Query Neighborhood Hits	32	Target Neighborhood Hits	114	Shared Neighborhood Hits	28
SwissProt Accessions	Q61476	Gene names	Cd55b, Daf2
Domain Architecture
Description	Complement decay-accelerating factor transmembrane isoform precursor (DAF-TM) (CD55 antigen).

CR2_MOUSE
θ value	1.81305 (rank : 24)	NC score	0.222543 (rank : 12)
Query Neighborhood Hits	32	Target Neighborhood Hits	101	Shared Neighborhood Hits	28
SwissProt Accessions	P19070	Gene names	Cr2
Domain Architecture
Description	Complement receptor type 2 precursor (Cr2) (Complement C3d receptor) (CD21 antigen).

LYAM3_HUMAN
θ value	1.81305 (rank : 25)	NC score	0.197588 (rank : 25)
Query Neighborhood Hits	32	Target Neighborhood Hits	378	Shared Neighborhood Hits	28
SwissProt Accessions	P16109, Q8IVD1	Gene names	SELP, GMRP
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

PERT_MOUSE
θ value	1.81305 (rank : 26)	NC score	0.068586 (rank : 52)
Query Neighborhood Hits	32	Target Neighborhood Hits	221	Shared Neighborhood Hits	27
SwissProt Accessions	P35419, Q8C8B1	Gene names	Tpo
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

DAF_HUMAN
θ value	2.36792 (rank : 27)	NC score	0.225584 (rank : 10)
Query Neighborhood Hits	32	Target Neighborhood Hits	97	Shared Neighborhood Hits	28
SwissProt Accessions	P08174, P09679, P78361	Gene names	CD55, CR, DAF
Domain Architecture
Description	Complement decay-accelerating factor precursor (CD55 antigen).

LYAM1_MOUSE
θ value	4.03905 (rank : 28)	NC score	0.162958 (rank : 33)
Query Neighborhood Hits	32	Target Neighborhood Hits	332	Shared Neighborhood Hits	28
SwissProt Accessions	P18337	Gene names	Sell, Lnhr, Ly-22
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Lymphocyte antigen 22) (Ly-22) (Lymphocyte surface MEL-14 antigen) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

DAF1_MOUSE
θ value	5.27518 (rank : 29)	NC score	0.215132 (rank : 14)
Query Neighborhood Hits	32	Target Neighborhood Hits	204	Shared Neighborhood Hits	28
SwissProt Accessions	Q61475, P97732, Q61397	Gene names	Cd55a, Daf1
Domain Architecture
Description	Complement decay-accelerating factor, GPI-anchored precursor (DAF-GPI) (CD55 antigen).

DBPA_MOUSE
θ value	6.88961 (rank : 30)	NC score	0.017601 (rank : 59)
Query Neighborhood Hits	32	Target Neighborhood Hits	64	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JKB3, Q80WG4, Q9EQF7, Q9EQF8	Gene names	Csda, Msy4, Ybx3
Domain Architecture	No domain graphic available
Description	DNA-binding protein A (Cold shock domain-containing protein A) (Y-box protein 3).

SYT5_HUMAN
θ value	6.88961 (rank : 31)	NC score	0.006686 (rank : 60)
Query Neighborhood Hits	32	Target Neighborhood Hits	138	Shared Neighborhood Hits	2
SwissProt Accessions	O00445, Q86X72	Gene names	SYT5
Domain Architecture
Description	Synaptotagmin-5 (Synaptotagmin V) (SytV).

WNK4_HUMAN
θ value	6.88961 (rank : 32)	NC score	0.001935 (rank : 61)
Query Neighborhood Hits	32	Target Neighborhood Hits	1043	Shared Neighborhood Hits	2
SwissProt Accessions	Q96J92, Q8N8X3, Q8N8Z2, Q96DT8, Q9BYS5	Gene names	WNK4, PRKWNK4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

APOH_MOUSE
θ value	θ > 10 (rank : 33)	NC score	0.185400 (rank : 28)
Query Neighborhood Hits	32	Target Neighborhood Hits	74	Shared Neighborhood Hits	26
SwissProt Accessions	Q01339	Gene names	Apoh, B2gp1
Domain Architecture
Description	Beta-2-glycoprotein 1 precursor (Beta-2-glycoprotein I) (Apolipoprotein H) (Apo-H) (B2GPI) (Beta(2)GPI) (Activated protein C- binding protein) (APC inhibitor).

C4BP_HUMAN
θ value	θ > 10 (rank : 34)	NC score	0.205853 (rank : 18)
Query Neighborhood Hits	32	Target Neighborhood Hits	92	Shared Neighborhood Hits	27
SwissProt Accessions	P04003	Gene names	C4BPA, C4BP
Domain Architecture
Description	C4b-binding protein alpha chain precursor (C4bp) (Proline-rich protein) (PRP).

CFAB_HUMAN
θ value	θ > 10 (rank : 35)	NC score	0.090607 (rank : 46)
Query Neighborhood Hits	32	Target Neighborhood Hits	251	Shared Neighborhood Hits	27
SwissProt Accessions	P00751, O15006, Q29944, Q96HX6, Q9BTF5, Q9BX92	Gene names	CFB, BF
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) (Properdin factor B) (Glycine-rich beta glycoprotein) (GBG) (PBF2) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

CFAB_MOUSE
θ value	θ > 10 (rank : 36)	NC score	0.087090 (rank : 49)
Query Neighborhood Hits	32	Target Neighborhood Hits	262	Shared Neighborhood Hits	26
SwissProt Accessions	P04186	Gene names	Cfb, Bf, H2-Bf
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

CFAH_HUMAN
θ value	θ > 10 (rank : 37)	NC score	0.169596 (rank : 32)
Query Neighborhood Hits	32	Target Neighborhood Hits	101	Shared Neighborhood Hits	27
SwissProt Accessions	P08603, P78435, Q14570, Q38G77, Q5TFM3, Q8N708, Q9NU86	Gene names	CFH, HF, HF1
Domain Architecture
Description	Complement factor H precursor (H factor 1).

CO2_HUMAN
θ value	θ > 10 (rank : 38)	NC score	0.087445 (rank : 48)
Query Neighborhood Hits	32	Target Neighborhood Hits	258	Shared Neighborhood Hits	25
SwissProt Accessions	P06681, O19694, Q13904	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

CO2_MOUSE
θ value	θ > 10 (rank : 39)	NC score	0.071232 (rank : 51)
Query Neighborhood Hits	32	Target Neighborhood Hits	250	Shared Neighborhood Hits	25
SwissProt Accessions	P21180	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

CO6_HUMAN
θ value	θ > 10 (rank : 40)	NC score	0.064063 (rank : 55)
Query Neighborhood Hits	32	Target Neighborhood Hits	331	Shared Neighborhood Hits	24
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

CO7_HUMAN
θ value	θ > 10 (rank : 41)	NC score	0.082362 (rank : 50)
Query Neighborhood Hits	32	Target Neighborhood Hits	278	Shared Neighborhood Hits	26
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

F13B_HUMAN
θ value	θ > 10 (rank : 42)	NC score	0.155752 (rank : 34)
Query Neighborhood Hits	32	Target Neighborhood Hits	84	Shared Neighborhood Hits	25
SwissProt Accessions	P05160	Gene names	F13B
Domain Architecture
Description	Coagulation factor XIII B chain precursor (Protein-glutamine gamma- glutamyltransferase B chain) (Transglutaminase B chain) (Fibrin- stabilizing factor B subunit).

F13B_MOUSE
θ value	θ > 10 (rank : 43)	NC score	0.155355 (rank : 35)
Query Neighborhood Hits	32	Target Neighborhood Hits	93	Shared Neighborhood Hits	26
SwissProt Accessions	Q07968	Gene names	F13b, Cf13b
Domain Architecture
Description	Coagulation factor XIII B chain precursor (Protein-glutamine gamma- glutamyltransferase B chain) (Transglutaminase B chain).

FHR1_HUMAN
θ value	θ > 10 (rank : 44)	NC score	0.123352 (rank : 40)
Query Neighborhood Hits	32	Target Neighborhood Hits	80	Shared Neighborhood Hits	25
SwissProt Accessions	Q03591, Q9UJ17	Gene names	CFHL1, CFHL, FHR1, HFL1
Domain Architecture
Description	Complement factor H-related protein 1 precursor (FHR-1) (H factor-like protein 1) (H-factor-like 1) (H36).

FHR2_HUMAN
θ value	θ > 10 (rank : 45)	NC score	0.107613 (rank : 43)
Query Neighborhood Hits	32	Target Neighborhood Hits	63	Shared Neighborhood Hits	25
SwissProt Accessions	P36980, Q14310	Gene names	CFHL2, FHR2, HFL3
Domain Architecture
Description	Complement factor H-related protein 2 precursor (FHR-2) (H factor-like protein 2) (H factor-like 3) (DDESK59).

FHR3_HUMAN
θ value	θ > 10 (rank : 46)	NC score	0.111883 (rank : 41)
Query Neighborhood Hits	32	Target Neighborhood Hits	74	Shared Neighborhood Hits	25
SwissProt Accessions	Q02985, Q9UJ16	Gene names	CFHL3, FHR3
Domain Architecture
Description	Complement factor H-related protein 3 precursor (FHR-3) (H factor-like protein 3) (DOWN16).

FHR4_HUMAN
θ value	θ > 10 (rank : 47)	NC score	0.108846 (rank : 42)
Query Neighborhood Hits	32	Target Neighborhood Hits	75	Shared Neighborhood Hits	25
SwissProt Accessions	Q92496, Q9UJY6	Gene names	CFHL4, FHR4
Domain Architecture
Description	Complement factor H-related protein 4 precursor (FHR-4).

FHR5_HUMAN
θ value	θ > 10 (rank : 48)	NC score	0.144295 (rank : 38)
Query Neighborhood Hits	32	Target Neighborhood Hits	77	Shared Neighborhood Hits	25
SwissProt Accessions	Q9BXR6	Gene names	CFHL5, FHR5
Domain Architecture
Description	Complement factor H-related protein 5 precursor (FHR-5).

GABR1_HUMAN
θ value	θ > 10 (rank : 49)	NC score	0.068447 (rank : 53)
Query Neighborhood Hits	32	Target Neighborhood Hits	142	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UBS5, O95375, O95468, O95975, O96022, Q86W60, Q9UQQ0	Gene names	GABBR1, GPRC3A
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 1 precursor (GABA-B receptor 1) (GABA-B-R1) (Gb1).

GABR1_MOUSE
θ value	θ > 10 (rank : 50)	NC score	0.068082 (rank : 54)
Query Neighborhood Hits	32	Target Neighborhood Hits	139	Shared Neighborhood Hits	25
SwissProt Accessions	Q9WV18, Q9WU48, Q9WV15, Q9WV16, Q9WV17	Gene names	Gabbr1
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 1 precursor (GABA-B receptor 1) (GABA-B-R1) (Gb1).

LYAM1_HUMAN
θ value	θ > 10 (rank : 51)	NC score	0.130854 (rank : 39)
Query Neighborhood Hits	32	Target Neighborhood Hits	315	Shared Neighborhood Hits	26
SwissProt Accessions	P14151, P15023	Gene names	SELL, LNHR, LYAM1
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Leukocyte surface antigen Leu-8) (TQ1) (gp90-MEL) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

MCP_MOUSE
θ value	θ > 10 (rank : 52)	NC score	0.216105 (rank : 13)
Query Neighborhood Hits	32	Target Neighborhood Hits	79	Shared Neighborhood Hits	26
SwissProt Accessions	O88174, Q9R0R9	Gene names	Cd46, Mcp
Domain Architecture	No domain graphic available
Description	Membrane cofactor protein precursor (CD46 antigen).

PAP2_HUMAN
θ value	θ > 10 (rank : 53)	NC score	0.087451 (rank : 47)
Query Neighborhood Hits	32	Target Neighborhood Hits	106	Shared Neighborhood Hits	22
SwissProt Accessions	Q9BXP8, Q96PH7, Q96PH8, Q9H4C9	Gene names	PAPPA2
Domain Architecture	No domain graphic available
Description	Pappalysin-2 precursor (EC 3.4.24.-) (Pregnancy-associated plasma protein-A2) (PAPP-A2) (Pregnancy-associated plasma protein-E1) (PAPP- E).

PAPPA_HUMAN
θ value	θ > 10 (rank : 54)	NC score	0.105246 (rank : 44)
Query Neighborhood Hits	32	Target Neighborhood Hits	161	Shared Neighborhood Hits	24
SwissProt Accessions	Q13219, Q08371, Q68G52, Q9UDK7	Gene names	PAPPA
Domain Architecture
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

PAPPA_MOUSE
θ value	θ > 10 (rank : 55)	NC score	0.102058 (rank : 45)
Query Neighborhood Hits	32	Target Neighborhood Hits	153	Shared Neighborhood Hits	23
SwissProt Accessions	Q8R4K8, Q80VW3, Q80YY1, Q8K423, Q8R4K7, Q9ES06, Q9JK57	Gene names	Pappa
Domain Architecture	No domain graphic available
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

PERT_HUMAN
θ value	θ > 10 (rank : 56)	NC score	0.050044 (rank : 58)
Query Neighborhood Hits	32	Target Neighborhood Hits	221	Shared Neighborhood Hits	25
SwissProt Accessions	P07202, P09934, P09935, Q8IUL0, Q8NF94, Q8NF95, Q8NF96, Q8NF97, Q8TCI9	Gene names	TPO
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

SRPX_HUMAN
θ value	θ > 10 (rank : 57)	NC score	0.174564 (rank : 31)
Query Neighborhood Hits	32	Target Neighborhood Hits	69	Shared Neighborhood Hits	27
SwissProt Accessions	P78539, Q99652, Q99913	Gene names	SRPX, ETX1
Domain Architecture
Description	Sushi repeat-containing protein SRPX precursor.

SRPX_MOUSE
θ value	θ > 10 (rank : 58)	NC score	0.174965 (rank : 30)
Query Neighborhood Hits	32	Target Neighborhood Hits	75	Shared Neighborhood Hits	27
SwissProt Accessions	Q9R0M3, Q9R0M2	Gene names	Srpx
Domain Architecture	No domain graphic available
Description	Sushi-repeat-containing protein SRPX precursor (DRS protein).

SUSD1_HUMAN
θ value	θ > 10 (rank : 59)	NC score	0.063561 (rank : 56)
Query Neighborhood Hits	32	Target Neighborhood Hits	285	Shared Neighborhood Hits	26
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

SUSD4_HUMAN
θ value	θ > 10 (rank : 60)	NC score	0.153779 (rank : 36)
Query Neighborhood Hits	32	Target Neighborhood Hits	88	Shared Neighborhood Hits	27
SwissProt Accessions	Q5VX71, Q6UX62, Q9BSR0, Q9NWG0	Gene names	SUSD4
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 4 precursor.

SUSD4_MOUSE
θ value	θ > 10 (rank : 61)	NC score	0.152754 (rank : 37)
Query Neighborhood Hits	32	Target Neighborhood Hits	122	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BH32, Q8VC43	Gene names	Susd4
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 4 precursor.

Hits sorted by NC score

SUSD3_HUMAN
NC score	0.999962 (rank : 1)	θ value	8.11517e-126 (rank : 1)
Query Neighborhood Hits	32	Target Neighborhood Hits	32	Shared Neighborhood Hits	32
SwissProt Accessions	Q96L08, Q49AA6, Q6UXV7	Gene names	SUSD3, UNQ9387/PRO34275
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 3.

SUSD3_MOUSE
NC score	0.949975 (rank : 2)	θ value	1.22964e-73 (rank : 2)
Query Neighborhood Hits	32	Target Neighborhood Hits	39	Shared Neighborhood Hits	27
SwissProt Accessions	Q9D176, Q80XL5, Q9CYV1, Q9DA86	Gene names	Susd3
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 3.

MCP_HUMAN
NC score	0.266934 (rank : 3)	θ value	0.00509761 (rank : 3)
Query Neighborhood Hits	32	Target Neighborhood Hits	82	Shared Neighborhood Hits	28
SwissProt Accessions	P15529, Q15429, Q53GV9, Q5HY94, Q5VWS6, Q5VWS7, Q5VWS8, Q5VWS9, Q5VWT0, Q5VWT1, Q5VWT2, Q6N0A1, Q7Z3R5, Q9NNW2, Q9NNW3, Q9NNW4	Gene names	CD46, MCP
Domain Architecture
Description	Membrane cofactor protein precursor (Trophoblast leukocyte common antigen) (TLX) (CD46 antigen).

CR1_HUMAN
NC score	0.262531 (rank : 4)	θ value	0.00869519 (rank : 4)
Query Neighborhood Hits	32	Target Neighborhood Hits	108	Shared Neighborhood Hits	28
SwissProt Accessions	P17927, Q16745, Q9UQV2	Gene names	CR1, C3BR
Domain Architecture
Description	Complement receptor type 1 precursor (C3b/C4b receptor) (CD35 antigen).

CRRY_MOUSE
NC score	0.244738 (rank : 5)	θ value	0.62314 (rank : 15)
Query Neighborhood Hits	32	Target Neighborhood Hits	84	Shared Neighborhood Hits	28
SwissProt Accessions	Q64735, Q3TV30, Q58E68, Q61447, Q61449, Q8CF59, Q8K328	Gene names	Crry, Cry
Domain Architecture	No domain graphic available
Description	Complement regulatory protein Crry precursor (Protein p65).

C4BB_HUMAN
NC score	0.242700 (rank : 6)	θ value	0.365318 (rank : 9)
Query Neighborhood Hits	32	Target Neighborhood Hits	77	Shared Neighborhood Hits	28
SwissProt Accessions	P20851	Gene names	C4BPB
Domain Architecture
Description	C4b-binding protein beta chain precursor.

CR2_HUMAN
NC score	0.233622 (rank : 7)	θ value	0.365318 (rank : 10)
Query Neighborhood Hits	32	Target Neighborhood Hits	89	Shared Neighborhood Hits	28
SwissProt Accessions	P20023, Q13866, Q14212	Gene names	CR2, C3DR
Domain Architecture
Description	Complement receptor type 2 precursor (Cr2) (Complement C3d receptor) (Epstein-Barr virus receptor) (EBV receptor) (CD21 antigen).

C4BP_MOUSE
NC score	0.231717 (rank : 8)	θ value	1.06291 (rank : 22)
Query Neighborhood Hits	32	Target Neighborhood Hits	91	Shared Neighborhood Hits	28
SwissProt Accessions	P08607	Gene names	C4bpa, C4bp
Domain Architecture
Description	C4b-binding protein precursor (C4bp).

ZP3R_MOUSE
NC score	0.229094 (rank : 9)	θ value	0.62314 (rank : 17)
Query Neighborhood Hits	32	Target Neighborhood Hits	81	Shared Neighborhood Hits	27
SwissProt Accessions	Q60736	Gene names	Zp3r, Sp56
Domain Architecture
Description	Zona pellucida sperm-binding protein 3 receptor precursor (Sperm fertilization protein 56) (sp56).

DAF_HUMAN
NC score	0.225584 (rank : 10)	θ value	2.36792 (rank : 27)
Query Neighborhood Hits	32	Target Neighborhood Hits	97	Shared Neighborhood Hits	28
SwissProt Accessions	P08174, P09679, P78361	Gene names	CD55, CR, DAF
Domain Architecture
Description	Complement decay-accelerating factor precursor (CD55 antigen).

DAF2_MOUSE
NC score	0.223622 (rank : 11)	θ value	1.06291 (rank : 23)
Query Neighborhood Hits	32	Target Neighborhood Hits	114	Shared Neighborhood Hits	28
SwissProt Accessions	Q61476	Gene names	Cd55b, Daf2
Domain Architecture
Description	Complement decay-accelerating factor transmembrane isoform precursor (DAF-TM) (CD55 antigen).

CR2_MOUSE
NC score	0.222543 (rank : 12)	θ value	1.81305 (rank : 24)
Query Neighborhood Hits	32	Target Neighborhood Hits	101	Shared Neighborhood Hits	28
SwissProt Accessions	P19070	Gene names	Cr2
Domain Architecture
Description	Complement receptor type 2 precursor (Cr2) (Complement C3d receptor) (CD21 antigen).

MCP_MOUSE
NC score	0.216105 (rank : 13)	θ value	θ > 10 (rank : 52)
Query Neighborhood Hits	32	Target Neighborhood Hits	79	Shared Neighborhood Hits	26
SwissProt Accessions	O88174, Q9R0R9	Gene names	Cd46, Mcp
Domain Architecture	No domain graphic available
Description	Membrane cofactor protein precursor (CD46 antigen).

DAF1_MOUSE
NC score	0.215132 (rank : 14)	θ value	5.27518 (rank : 29)
Query Neighborhood Hits	32	Target Neighborhood Hits	204	Shared Neighborhood Hits	28
SwissProt Accessions	Q61475, P97732, Q61397	Gene names	Cd55a, Daf1
Domain Architecture
Description	Complement decay-accelerating factor, GPI-anchored precursor (DAF-GPI) (CD55 antigen).

CSMD1_HUMAN
NC score	0.208364 (rank : 15)	θ value	0.0330416 (rank : 6)
Query Neighborhood Hits	32	Target Neighborhood Hits	176	Shared Neighborhood Hits	28
SwissProt Accessions	Q96PZ7, Q96QU9, Q96RM4	Gene names	CSMD1, KIAA1890
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

SUSD2_HUMAN
NC score	0.207697 (rank : 16)	θ value	0.62314 (rank : 16)
Query Neighborhood Hits	32	Target Neighborhood Hits	99	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UGT4, Q9H5Y6	Gene names	SUSD2
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 2 precursor.

CSMD2_HUMAN
NC score	0.206754 (rank : 17)	θ value	0.0148317 (rank : 5)
Query Neighborhood Hits	32	Target Neighborhood Hits	188	Shared Neighborhood Hits	28
SwissProt Accessions	Q7Z408, Q5VT59, Q8N963, Q96Q03, Q9H4V7, Q9H4V8, Q9H4V9, Q9H4W0, Q9H4W1, Q9H4W2, Q9H4W3, Q9H4W4, Q9HCY5, Q9HCY6, Q9HCY7	Gene names	CSMD2, KIAA1884
Domain Architecture
Description	CUB and sushi domain-containing protein 2 (CUB and sushi multiple domains protein 2).

C4BP_HUMAN
NC score	0.205853 (rank : 18)	θ value	θ > 10 (rank : 34)
Query Neighborhood Hits	32	Target Neighborhood Hits	92	Shared Neighborhood Hits	27
SwissProt Accessions	P04003	Gene names	C4BPA, C4BP
Domain Architecture
Description	C4b-binding protein alpha chain precursor (C4bp) (Proline-rich protein) (PRP).

SEZ6L_HUMAN
NC score	0.205014 (rank : 19)	θ value	0.365318 (rank : 11)
Query Neighborhood Hits	32	Target Neighborhood Hits	289	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.

LYAM3_MOUSE
NC score	0.203067 (rank : 20)	θ value	0.47712 (rank : 14)
Query Neighborhood Hits	32	Target Neighborhood Hits	390	Shared Neighborhood Hits	28
SwissProt Accessions	Q01102	Gene names	Selp, Grmp
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

APOH_HUMAN
NC score	0.200793 (rank : 21)	θ value	1.06291 (rank : 21)
Query Neighborhood Hits	32	Target Neighborhood Hits	75	Shared Neighborhood Hits	27
SwissProt Accessions	P02749, Q9UCN7	Gene names	APOH, B2G1
Domain Architecture
Description	Beta-2-glycoprotein 1 precursor (Beta-2-glycoprotein I) (Apolipoprotein H) (Apo-H) (B2GPI) (Beta(2)GPI) (Activated protein C- binding protein) (APC inhibitor) (Anticardiolipin cofactor).

CSMD1_MOUSE
NC score	0.200517 (rank : 22)	θ value	0.47712 (rank : 12)
Query Neighborhood Hits	32	Target Neighborhood Hits	193	Shared Neighborhood Hits	28
SwissProt Accessions	Q923L3, Q8BUV1, Q8BYQ3	Gene names	Csmd1
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

LYAM2_MOUSE
NC score	0.198261 (rank : 23)	θ value	0.0563607 (rank : 7)
Query Neighborhood Hits	32	Target Neighborhood Hits	420	Shared Neighborhood Hits	28
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

CSMD3_HUMAN
NC score	0.197911 (rank : 24)	θ value	0.47712 (rank : 13)
Query Neighborhood Hits	32	Target Neighborhood Hits	199	Shared Neighborhood Hits	28
SwissProt Accessions	Q7Z407, Q96PZ3	Gene names	CSMD3, KIAA1894
Domain Architecture
Description	CUB and sushi domain-containing protein 3 precursor (CUB and sushi multiple domains protein 3).

LYAM3_HUMAN
NC score	0.197588 (rank : 25)	θ value	1.81305 (rank : 25)
Query Neighborhood Hits	32	Target Neighborhood Hits	378	Shared Neighborhood Hits	28
SwissProt Accessions	P16109, Q8IVD1	Gene names	SELP, GMRP
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

LYAM2_HUMAN
NC score	0.190807 (rank : 26)	θ value	0.813845 (rank : 19)
Query Neighborhood Hits	32	Target Neighborhood Hits	394	Shared Neighborhood Hits	28
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

SUSD2_MOUSE
NC score	0.189135 (rank : 27)	θ value	0.813845 (rank : 20)
Query Neighborhood Hits	32	Target Neighborhood Hits	104	Shared Neighborhood Hits	29
SwissProt Accessions	Q9DBX3, Q8BY19, Q8BYN0, Q8BYZ3, Q8BYZ9, Q8BZQ4, Q8C179	Gene names	Susd2
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 2 precursor.

APOH_MOUSE
NC score	0.185400 (rank : 28)	θ value	θ > 10 (rank : 33)
Query Neighborhood Hits	32	Target Neighborhood Hits	74	Shared Neighborhood Hits	26
SwissProt Accessions	Q01339	Gene names	Apoh, B2gp1
Domain Architecture
Description	Beta-2-glycoprotein 1 precursor (Beta-2-glycoprotein I) (Apolipoprotein H) (Apo-H) (B2GPI) (Beta(2)GPI) (Activated protein C- binding protein) (APC inhibitor).

CFAH_MOUSE
NC score	0.178718 (rank : 29)	θ value	0.813845 (rank : 18)
Query Neighborhood Hits	32	Target Neighborhood Hits	112	Shared Neighborhood Hits	28
SwissProt Accessions	P06909	Gene names	Cfh, Hf1
Domain Architecture
Description	Complement factor H precursor (Protein beta-1-H).

SRPX_MOUSE
NC score	0.174965 (rank : 30)	θ value	θ > 10 (rank : 58)
Query Neighborhood Hits	32	Target Neighborhood Hits	75	Shared Neighborhood Hits	27
SwissProt Accessions	Q9R0M3, Q9R0M2	Gene names	Srpx
Domain Architecture	No domain graphic available
Description	Sushi-repeat-containing protein SRPX precursor (DRS protein).

SRPX_HUMAN
NC score	0.174564 (rank : 31)	θ value	θ > 10 (rank : 57)
Query Neighborhood Hits	32	Target Neighborhood Hits	69	Shared Neighborhood Hits	27
SwissProt Accessions	P78539, Q99652, Q99913	Gene names	SRPX, ETX1
Domain Architecture
Description	Sushi repeat-containing protein SRPX precursor.

CFAH_HUMAN
NC score	0.169596 (rank : 32)	θ value	θ > 10 (rank : 37)
Query Neighborhood Hits	32	Target Neighborhood Hits	101	Shared Neighborhood Hits	27
SwissProt Accessions	P08603, P78435, Q14570, Q38G77, Q5TFM3, Q8N708, Q9NU86	Gene names	CFH, HF, HF1
Domain Architecture
Description	Complement factor H precursor (H factor 1).

LYAM1_MOUSE
NC score	0.162958 (rank : 33)	θ value	4.03905 (rank : 28)
Query Neighborhood Hits	32	Target Neighborhood Hits	332	Shared Neighborhood Hits	28
SwissProt Accessions	P18337	Gene names	Sell, Lnhr, Ly-22
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Lymphocyte antigen 22) (Ly-22) (Lymphocyte surface MEL-14 antigen) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

F13B_HUMAN
NC score	0.155752 (rank : 34)	θ value	θ > 10 (rank : 42)
Query Neighborhood Hits	32	Target Neighborhood Hits	84	Shared Neighborhood Hits	25
SwissProt Accessions	P05160	Gene names	F13B
Domain Architecture
Description	Coagulation factor XIII B chain precursor (Protein-glutamine gamma- glutamyltransferase B chain) (Transglutaminase B chain) (Fibrin- stabilizing factor B subunit).

F13B_MOUSE
NC score	0.155355 (rank : 35)	θ value	θ > 10 (rank : 43)
Query Neighborhood Hits	32	Target Neighborhood Hits	93	Shared Neighborhood Hits	26
SwissProt Accessions	Q07968	Gene names	F13b, Cf13b
Domain Architecture
Description	Coagulation factor XIII B chain precursor (Protein-glutamine gamma- glutamyltransferase B chain) (Transglutaminase B chain).

SUSD4_HUMAN
NC score	0.153779 (rank : 36)	θ value	θ > 10 (rank : 60)
Query Neighborhood Hits	32	Target Neighborhood Hits	88	Shared Neighborhood Hits	27
SwissProt Accessions	Q5VX71, Q6UX62, Q9BSR0, Q9NWG0	Gene names	SUSD4
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 4 precursor.

SUSD4_MOUSE
NC score	0.152754 (rank : 37)	θ value	θ > 10 (rank : 61)
Query Neighborhood Hits	32	Target Neighborhood Hits	122	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BH32, Q8VC43	Gene names	Susd4
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 4 precursor.

FHR5_HUMAN
NC score	0.144295 (rank : 38)	θ value	θ > 10 (rank : 48)
Query Neighborhood Hits	32	Target Neighborhood Hits	77	Shared Neighborhood Hits	25
SwissProt Accessions	Q9BXR6	Gene names	CFHL5, FHR5
Domain Architecture
Description	Complement factor H-related protein 5 precursor (FHR-5).

LYAM1_HUMAN
NC score	0.130854 (rank : 39)	θ value	θ > 10 (rank : 51)
Query Neighborhood Hits	32	Target Neighborhood Hits	315	Shared Neighborhood Hits	26
SwissProt Accessions	P14151, P15023	Gene names	SELL, LNHR, LYAM1
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Leukocyte surface antigen Leu-8) (TQ1) (gp90-MEL) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

FHR1_HUMAN
NC score	0.123352 (rank : 40)	θ value	θ > 10 (rank : 44)
Query Neighborhood Hits	32	Target Neighborhood Hits	80	Shared Neighborhood Hits	25
SwissProt Accessions	Q03591, Q9UJ17	Gene names	CFHL1, CFHL, FHR1, HFL1
Domain Architecture
Description	Complement factor H-related protein 1 precursor (FHR-1) (H factor-like protein 1) (H-factor-like 1) (H36).

FHR3_HUMAN
NC score	0.111883 (rank : 41)	θ value	θ > 10 (rank : 46)
Query Neighborhood Hits	32	Target Neighborhood Hits	74	Shared Neighborhood Hits	25
SwissProt Accessions	Q02985, Q9UJ16	Gene names	CFHL3, FHR3
Domain Architecture
Description	Complement factor H-related protein 3 precursor (FHR-3) (H factor-like protein 3) (DOWN16).

FHR4_HUMAN
NC score	0.108846 (rank : 42)	θ value	θ > 10 (rank : 47)
Query Neighborhood Hits	32	Target Neighborhood Hits	75	Shared Neighborhood Hits	25
SwissProt Accessions	Q92496, Q9UJY6	Gene names	CFHL4, FHR4
Domain Architecture
Description	Complement factor H-related protein 4 precursor (FHR-4).

FHR2_HUMAN
NC score	0.107613 (rank : 43)	θ value	θ > 10 (rank : 45)
Query Neighborhood Hits	32	Target Neighborhood Hits	63	Shared Neighborhood Hits	25
SwissProt Accessions	P36980, Q14310	Gene names	CFHL2, FHR2, HFL3
Domain Architecture
Description	Complement factor H-related protein 2 precursor (FHR-2) (H factor-like protein 2) (H factor-like 3) (DDESK59).

PAPPA_HUMAN
NC score	0.105246 (rank : 44)	θ value	θ > 10 (rank : 54)
Query Neighborhood Hits	32	Target Neighborhood Hits	161	Shared Neighborhood Hits	24
SwissProt Accessions	Q13219, Q08371, Q68G52, Q9UDK7	Gene names	PAPPA
Domain Architecture
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

PAPPA_MOUSE
NC score	0.102058 (rank : 45)	θ value	θ > 10 (rank : 55)
Query Neighborhood Hits	32	Target Neighborhood Hits	153	Shared Neighborhood Hits	23
SwissProt Accessions	Q8R4K8, Q80VW3, Q80YY1, Q8K423, Q8R4K7, Q9ES06, Q9JK57	Gene names	Pappa
Domain Architecture	No domain graphic available
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

CFAB_HUMAN
NC score	0.090607 (rank : 46)	θ value	θ > 10 (rank : 35)
Query Neighborhood Hits	32	Target Neighborhood Hits	251	Shared Neighborhood Hits	27
SwissProt Accessions	P00751, O15006, Q29944, Q96HX6, Q9BTF5, Q9BX92	Gene names	CFB, BF
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) (Properdin factor B) (Glycine-rich beta glycoprotein) (GBG) (PBF2) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

PAP2_HUMAN
NC score	0.087451 (rank : 47)	θ value	θ > 10 (rank : 53)
Query Neighborhood Hits	32	Target Neighborhood Hits	106	Shared Neighborhood Hits	22
SwissProt Accessions	Q9BXP8, Q96PH7, Q96PH8, Q9H4C9	Gene names	PAPPA2
Domain Architecture	No domain graphic available
Description	Pappalysin-2 precursor (EC 3.4.24.-) (Pregnancy-associated plasma protein-A2) (PAPP-A2) (Pregnancy-associated plasma protein-E1) (PAPP- E).

CO2_HUMAN
NC score	0.087445 (rank : 48)	θ value	θ > 10 (rank : 38)
Query Neighborhood Hits	32	Target Neighborhood Hits	258	Shared Neighborhood Hits	25
SwissProt Accessions	P06681, O19694, Q13904	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

CFAB_MOUSE
NC score	0.087090 (rank : 49)	θ value	θ > 10 (rank : 36)
Query Neighborhood Hits	32	Target Neighborhood Hits	262	Shared Neighborhood Hits	26
SwissProt Accessions	P04186	Gene names	Cfb, Bf, H2-Bf
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

CO7_HUMAN
NC score	0.082362 (rank : 50)	θ value	θ > 10 (rank : 41)
Query Neighborhood Hits	32	Target Neighborhood Hits	278	Shared Neighborhood Hits	26
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

CO2_MOUSE
NC score	0.071232 (rank : 51)	θ value	θ > 10 (rank : 39)
Query Neighborhood Hits	32	Target Neighborhood Hits	250	Shared Neighborhood Hits	25
SwissProt Accessions	P21180	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

PERT_MOUSE
NC score	0.068586 (rank : 52)	θ value	1.81305 (rank : 26)
Query Neighborhood Hits	32	Target Neighborhood Hits	221	Shared Neighborhood Hits	27
SwissProt Accessions	P35419, Q8C8B1	Gene names	Tpo
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

GABR1_HUMAN
NC score	0.068447 (rank : 53)	θ value	θ > 10 (rank : 49)
Query Neighborhood Hits	32	Target Neighborhood Hits	142	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UBS5, O95375, O95468, O95975, O96022, Q86W60, Q9UQQ0	Gene names	GABBR1, GPRC3A
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 1 precursor (GABA-B receptor 1) (GABA-B-R1) (Gb1).

GABR1_MOUSE
NC score	0.068082 (rank : 54)	θ value	θ > 10 (rank : 50)
Query Neighborhood Hits	32	Target Neighborhood Hits	139	Shared Neighborhood Hits	25
SwissProt Accessions	Q9WV18, Q9WU48, Q9WV15, Q9WV16, Q9WV17	Gene names	Gabbr1
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 1 precursor (GABA-B receptor 1) (GABA-B-R1) (Gb1).

CO6_HUMAN
NC score	0.064063 (rank : 55)	θ value	θ > 10 (rank : 40)
Query Neighborhood Hits	32	Target Neighborhood Hits	331	Shared Neighborhood Hits	24
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

SUSD1_HUMAN
NC score	0.063561 (rank : 56)	θ value	θ > 10 (rank : 59)
Query Neighborhood Hits	32	Target Neighborhood Hits	285	Shared Neighborhood Hits	26
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

I10R2_HUMAN
NC score	0.063140 (rank : 57)	θ value	0.279714 (rank : 8)
Query Neighborhood Hits	32	Target Neighborhood Hits	43	Shared Neighborhood Hits	3
SwissProt Accessions	Q08334, Q9BUU4	Gene names	IL10RB, CRFB4
Domain Architecture
Description	Interleukin-10 receptor beta chain precursor (IL-10R-B) (IL-10R2) (Cytokine receptor family 2 member 4) (Cytokine receptor class-II member 4) (CRF2-4) (CDw210b antigen).

PERT_HUMAN
NC score	0.050044 (rank : 58)	θ value	θ > 10 (rank : 56)
Query Neighborhood Hits	32	Target Neighborhood Hits	221	Shared Neighborhood Hits	25
SwissProt Accessions	P07202, P09934, P09935, Q8IUL0, Q8NF94, Q8NF95, Q8NF96, Q8NF97, Q8TCI9	Gene names	TPO
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

DBPA_MOUSE
NC score	0.017601 (rank : 59)	θ value	6.88961 (rank : 30)
Query Neighborhood Hits	32	Target Neighborhood Hits	64	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JKB3, Q80WG4, Q9EQF7, Q9EQF8	Gene names	Csda, Msy4, Ybx3
Domain Architecture	No domain graphic available
Description	DNA-binding protein A (Cold shock domain-containing protein A) (Y-box protein 3).

SYT5_HUMAN
NC score	0.006686 (rank : 60)	θ value	6.88961 (rank : 31)
Query Neighborhood Hits	32	Target Neighborhood Hits	138	Shared Neighborhood Hits	2
SwissProt Accessions	O00445, Q86X72	Gene names	SYT5
Domain Architecture
Description	Synaptotagmin-5 (Synaptotagmin V) (SytV).

WNK4_HUMAN
NC score	0.001935 (rank : 61)	θ value	6.88961 (rank : 32)
Query Neighborhood Hits	32	Target Neighborhood Hits	1043	Shared Neighborhood Hits	2
SwissProt Accessions	Q96J92, Q8N8X3, Q8N8Z2, Q96DT8, Q9BYS5	Gene names	WNK4, PRKWNK4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).