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Network neighborhood for query Sequence : C4BB_HUMAN

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C4BB_HUMAN
SwissProt Accessions	P20851	Gene names	C4BPB
Domain Architecture
Description	C4b-binding protein beta chain precursor.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

C4BB_HUMAN
θ value	1.12714e-143 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	77	Target Neighborhood Hits	77	Shared Neighborhood Hits	77
SwissProt Accessions	P20851	Gene names	C4BPB
Domain Architecture
Description	C4b-binding protein beta chain precursor.

CSMD1_HUMAN
θ value	5.97985e-28 (rank : 2)	NC score	0.739925 (rank : 24)
Query Neighborhood Hits	77	Target Neighborhood Hits	176	Shared Neighborhood Hits	69
SwissProt Accessions	Q96PZ7, Q96QU9, Q96RM4	Gene names	CSMD1, KIAA1890
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

CSMD1_MOUSE
θ value	4.9032e-22 (rank : 3)	NC score	0.733539 (rank : 25)
Query Neighborhood Hits	77	Target Neighborhood Hits	193	Shared Neighborhood Hits	72
SwissProt Accessions	Q923L3, Q8BUV1, Q8BYQ3	Gene names	Csmd1
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

CSMD3_HUMAN
θ value	4.9032e-22 (rank : 4)	NC score	0.741707 (rank : 23)
Query Neighborhood Hits	77	Target Neighborhood Hits	199	Shared Neighborhood Hits	69
SwissProt Accessions	Q7Z407, Q96PZ3	Gene names	CSMD3, KIAA1894
Domain Architecture
Description	CUB and sushi domain-containing protein 3 precursor (CUB and sushi multiple domains protein 3).

CSMD2_HUMAN
θ value	7.0802e-21 (rank : 5)	NC score	0.722285 (rank : 28)
Query Neighborhood Hits	77	Target Neighborhood Hits	188	Shared Neighborhood Hits	68
SwissProt Accessions	Q7Z408, Q5VT59, Q8N963, Q96Q03, Q9H4V7, Q9H4V8, Q9H4V9, Q9H4W0, Q9H4W1, Q9H4W2, Q9H4W3, Q9H4W4, Q9HCY5, Q9HCY6, Q9HCY7	Gene names	CSMD2, KIAA1884
Domain Architecture
Description	CUB and sushi domain-containing protein 2 (CUB and sushi multiple domains protein 2).

CR2_MOUSE
θ value	2.97466e-19 (rank : 6)	NC score	0.879174 (rank : 2)
Query Neighborhood Hits	77	Target Neighborhood Hits	101	Shared Neighborhood Hits	68
SwissProt Accessions	P19070	Gene names	Cr2
Domain Architecture
Description	Complement receptor type 2 precursor (Cr2) (Complement C3d receptor) (CD21 antigen).

LYAM2_MOUSE
θ value	1.47631e-18 (rank : 7)	NC score	0.722385 (rank : 27)
Query Neighborhood Hits	77	Target Neighborhood Hits	420	Shared Neighborhood Hits	76
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

CR2_HUMAN
θ value	7.32683e-18 (rank : 8)	NC score	0.875979 (rank : 3)
Query Neighborhood Hits	77	Target Neighborhood Hits	89	Shared Neighborhood Hits	69
SwissProt Accessions	P20023, Q13866, Q14212	Gene names	CR2, C3DR
Domain Architecture
Description	Complement receptor type 2 precursor (Cr2) (Complement C3d receptor) (Epstein-Barr virus receptor) (EBV receptor) (CD21 antigen).

CFAB_HUMAN
θ value	2.13179e-17 (rank : 9)	NC score	0.535666 (rank : 43)
Query Neighborhood Hits	77	Target Neighborhood Hits	251	Shared Neighborhood Hits	64
SwissProt Accessions	P00751, O15006, Q29944, Q96HX6, Q9BTF5, Q9BX92	Gene names	CFB, BF
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) (Properdin factor B) (Glycine-rich beta glycoprotein) (GBG) (PBF2) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

CFAB_MOUSE
θ value	4.74913e-17 (rank : 10)	NC score	0.536549 (rank : 42)
Query Neighborhood Hits	77	Target Neighborhood Hits	262	Shared Neighborhood Hits	64
SwissProt Accessions	P04186	Gene names	Cfb, Bf, H2-Bf
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

LYAM2_HUMAN
θ value	6.20254e-17 (rank : 11)	NC score	0.727711 (rank : 26)
Query Neighborhood Hits	77	Target Neighborhood Hits	394	Shared Neighborhood Hits	75
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

SEZ6L_HUMAN
θ value	4.02038e-16 (rank : 12)	NC score	0.718077 (rank : 29)
Query Neighborhood Hits	77	Target Neighborhood Hits	289	Shared Neighborhood Hits	68
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.

LYAM3_MOUSE
θ value	6.85773e-16 (rank : 13)	NC score	0.742275 (rank : 22)
Query Neighborhood Hits	77	Target Neighborhood Hits	390	Shared Neighborhood Hits	76
SwissProt Accessions	Q01102	Gene names	Selp, Grmp
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

LYAM3_HUMAN
θ value	5.8054e-15 (rank : 14)	NC score	0.747704 (rank : 21)
Query Neighborhood Hits	77	Target Neighborhood Hits	378	Shared Neighborhood Hits	75
SwissProt Accessions	P16109, Q8IVD1	Gene names	SELP, GMRP
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

CR1_HUMAN
θ value	3.76295e-14 (rank : 15)	NC score	0.860115 (rank : 6)
Query Neighborhood Hits	77	Target Neighborhood Hits	108	Shared Neighborhood Hits	67
SwissProt Accessions	P17927, Q16745, Q9UQV2	Gene names	CR1, C3BR
Domain Architecture
Description	Complement receptor type 1 precursor (C3b/C4b receptor) (CD35 antigen).

CO2_HUMAN
θ value	7.09661e-13 (rank : 16)	NC score	0.526859 (rank : 44)
Query Neighborhood Hits	77	Target Neighborhood Hits	258	Shared Neighborhood Hits	60
SwissProt Accessions	P06681, O19694, Q13904	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

C4BP_MOUSE
θ value	1.2105e-12 (rank : 17)	NC score	0.874858 (rank : 4)
Query Neighborhood Hits	77	Target Neighborhood Hits	91	Shared Neighborhood Hits	67
SwissProt Accessions	P08607	Gene names	C4bpa, C4bp
Domain Architecture
Description	C4b-binding protein precursor (C4bp).

C4BP_HUMAN
θ value	2.69671e-12 (rank : 18)	NC score	0.864776 (rank : 5)
Query Neighborhood Hits	77	Target Neighborhood Hits	92	Shared Neighborhood Hits	66
SwissProt Accessions	P04003	Gene names	C4BPA, C4BP
Domain Architecture
Description	C4b-binding protein alpha chain precursor (C4bp) (Proline-rich protein) (PRP).

F13B_MOUSE
θ value	1.74796e-11 (rank : 19)	NC score	0.820227 (rank : 14)
Query Neighborhood Hits	77	Target Neighborhood Hits	93	Shared Neighborhood Hits	62
SwissProt Accessions	Q07968	Gene names	F13b, Cf13b
Domain Architecture
Description	Coagulation factor XIII B chain precursor (Protein-glutamine gamma- glutamyltransferase B chain) (Transglutaminase B chain).

DAF_HUMAN
θ value	2.28291e-11 (rank : 20)	NC score	0.846104 (rank : 12)
Query Neighborhood Hits	77	Target Neighborhood Hits	97	Shared Neighborhood Hits	66
SwissProt Accessions	P08174, P09679, P78361	Gene names	CD55, CR, DAF
Domain Architecture
Description	Complement decay-accelerating factor precursor (CD55 antigen).

ZP3R_MOUSE
θ value	3.89403e-11 (rank : 21)	NC score	0.854100 (rank : 8)
Query Neighborhood Hits	77	Target Neighborhood Hits	81	Shared Neighborhood Hits	65
SwissProt Accessions	Q60736	Gene names	Zp3r, Sp56
Domain Architecture
Description	Zona pellucida sperm-binding protein 3 receptor precursor (Sperm fertilization protein 56) (sp56).

CRRY_MOUSE
θ value	8.67504e-11 (rank : 22)	NC score	0.853214 (rank : 9)
Query Neighborhood Hits	77	Target Neighborhood Hits	84	Shared Neighborhood Hits	68
SwissProt Accessions	Q64735, Q3TV30, Q58E68, Q61447, Q61449, Q8CF59, Q8K328	Gene names	Crry, Cry
Domain Architecture	No domain graphic available
Description	Complement regulatory protein Crry precursor (Protein p65).

APOH_MOUSE
θ value	1.47974e-10 (rank : 23)	NC score	0.850150 (rank : 11)
Query Neighborhood Hits	77	Target Neighborhood Hits	74	Shared Neighborhood Hits	63
SwissProt Accessions	Q01339	Gene names	Apoh, B2gp1
Domain Architecture
Description	Beta-2-glycoprotein 1 precursor (Beta-2-glycoprotein I) (Apolipoprotein H) (Apo-H) (B2GPI) (Beta(2)GPI) (Activated protein C- binding protein) (APC inhibitor).

F13B_HUMAN
θ value	2.52405e-10 (rank : 24)	NC score	0.802750 (rank : 17)
Query Neighborhood Hits	77	Target Neighborhood Hits	84	Shared Neighborhood Hits	62
SwissProt Accessions	P05160	Gene names	F13B
Domain Architecture
Description	Coagulation factor XIII B chain precursor (Protein-glutamine gamma- glutamyltransferase B chain) (Transglutaminase B chain) (Fibrin- stabilizing factor B subunit).

APOH_HUMAN
θ value	3.29651e-10 (rank : 25)	NC score	0.856274 (rank : 7)
Query Neighborhood Hits	77	Target Neighborhood Hits	75	Shared Neighborhood Hits	66
SwissProt Accessions	P02749, Q9UCN7	Gene names	APOH, B2G1
Domain Architecture
Description	Beta-2-glycoprotein 1 precursor (Beta-2-glycoprotein I) (Apolipoprotein H) (Apo-H) (B2GPI) (Beta(2)GPI) (Activated protein C- binding protein) (APC inhibitor) (Anticardiolipin cofactor).

MCP_MOUSE
θ value	5.62301e-10 (rank : 26)	NC score	0.839887 (rank : 13)
Query Neighborhood Hits	77	Target Neighborhood Hits	79	Shared Neighborhood Hits	64
SwissProt Accessions	O88174, Q9R0R9	Gene names	Cd46, Mcp
Domain Architecture	No domain graphic available
Description	Membrane cofactor protein precursor (CD46 antigen).

FHR5_HUMAN
θ value	7.34386e-10 (rank : 27)	NC score	0.750485 (rank : 20)
Query Neighborhood Hits	77	Target Neighborhood Hits	77	Shared Neighborhood Hits	61
SwissProt Accessions	Q9BXR6	Gene names	CFHL5, FHR5
Domain Architecture
Description	Complement factor H-related protein 5 precursor (FHR-5).

CFAH_HUMAN
θ value	9.59137e-10 (rank : 28)	NC score	0.797106 (rank : 19)
Query Neighborhood Hits	77	Target Neighborhood Hits	101	Shared Neighborhood Hits	66
SwissProt Accessions	P08603, P78435, Q14570, Q38G77, Q5TFM3, Q8N708, Q9NU86	Gene names	CFH, HF, HF1
Domain Architecture
Description	Complement factor H precursor (H factor 1).

CFAH_MOUSE
θ value	9.59137e-10 (rank : 29)	NC score	0.801892 (rank : 18)
Query Neighborhood Hits	77	Target Neighborhood Hits	112	Shared Neighborhood Hits	68
SwissProt Accessions	P06909	Gene names	Cfh, Hf1
Domain Architecture
Description	Complement factor H precursor (Protein beta-1-H).

MCP_HUMAN
θ value	1.63604e-09 (rank : 30)	NC score	0.851146 (rank : 10)
Query Neighborhood Hits	77	Target Neighborhood Hits	82	Shared Neighborhood Hits	66
SwissProt Accessions	P15529, Q15429, Q53GV9, Q5HY94, Q5VWS6, Q5VWS7, Q5VWS8, Q5VWS9, Q5VWT0, Q5VWT1, Q5VWT2, Q6N0A1, Q7Z3R5, Q9NNW2, Q9NNW3, Q9NNW4	Gene names	CD46, MCP
Domain Architecture
Description	Membrane cofactor protein precursor (Trophoblast leukocyte common antigen) (TLX) (CD46 antigen).

DAF1_MOUSE
θ value	2.79066e-09 (rank : 31)	NC score	0.806931 (rank : 16)
Query Neighborhood Hits	77	Target Neighborhood Hits	204	Shared Neighborhood Hits	68
SwissProt Accessions	Q61475, P97732, Q61397	Gene names	Cd55a, Daf1
Domain Architecture
Description	Complement decay-accelerating factor, GPI-anchored precursor (DAF-GPI) (CD55 antigen).

LYAM1_MOUSE
θ value	1.80886e-08 (rank : 32)	NC score	0.559595 (rank : 38)
Query Neighborhood Hits	77	Target Neighborhood Hits	332	Shared Neighborhood Hits	65
SwissProt Accessions	P18337	Gene names	Sell, Lnhr, Ly-22
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Lymphocyte antigen 22) (Ly-22) (Lymphocyte surface MEL-14 antigen) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

FHR1_HUMAN
θ value	1.53129e-07 (rank : 33)	NC score	0.700078 (rank : 34)
Query Neighborhood Hits	77	Target Neighborhood Hits	80	Shared Neighborhood Hits	60
SwissProt Accessions	Q03591, Q9UJ17	Gene names	CFHL1, CFHL, FHR1, HFL1
Domain Architecture
Description	Complement factor H-related protein 1 precursor (FHR-1) (H factor-like protein 1) (H-factor-like 1) (H36).

FHR2_HUMAN
θ value	1.53129e-07 (rank : 34)	NC score	0.653925 (rank : 36)
Query Neighborhood Hits	77	Target Neighborhood Hits	63	Shared Neighborhood Hits	56
SwissProt Accessions	P36980, Q14310	Gene names	CFHL2, FHR2, HFL3
Domain Architecture
Description	Complement factor H-related protein 2 precursor (FHR-2) (H factor-like protein 2) (H factor-like 3) (DDESK59).

DAF2_MOUSE
θ value	2.61198e-07 (rank : 35)	NC score	0.807294 (rank : 15)
Query Neighborhood Hits	77	Target Neighborhood Hits	114	Shared Neighborhood Hits	67
SwissProt Accessions	Q61476	Gene names	Cd55b, Daf2
Domain Architecture
Description	Complement decay-accelerating factor transmembrane isoform precursor (DAF-TM) (CD55 antigen).

FHR3_HUMAN
θ value	9.92553e-07 (rank : 36)	NC score	0.673501 (rank : 35)
Query Neighborhood Hits	77	Target Neighborhood Hits	74	Shared Neighborhood Hits	59
SwissProt Accessions	Q02985, Q9UJ16	Gene names	CFHL3, FHR3
Domain Architecture
Description	Complement factor H-related protein 3 precursor (FHR-3) (H factor-like protein 3) (DOWN16).

CO2_MOUSE
θ value	2.21117e-06 (rank : 37)	NC score	0.453358 (rank : 48)
Query Neighborhood Hits	77	Target Neighborhood Hits	250	Shared Neighborhood Hits	61
SwissProt Accessions	P21180	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

SRPX_HUMAN
θ value	3.77169e-06 (rank : 38)	NC score	0.707083 (rank : 32)
Query Neighborhood Hits	77	Target Neighborhood Hits	69	Shared Neighborhood Hits	55
SwissProt Accessions	P78539, Q99652, Q99913	Gene names	SRPX, ETX1
Domain Architecture
Description	Sushi repeat-containing protein SRPX precursor.

SRPX_MOUSE
θ value	3.77169e-06 (rank : 39)	NC score	0.716223 (rank : 30)
Query Neighborhood Hits	77	Target Neighborhood Hits	75	Shared Neighborhood Hits	57
SwissProt Accessions	Q9R0M3, Q9R0M2	Gene names	Srpx
Domain Architecture	No domain graphic available
Description	Sushi-repeat-containing protein SRPX precursor (DRS protein).

MASP2_HUMAN
θ value	4.92598e-06 (rank : 40)	NC score	0.249968 (rank : 56)
Query Neighborhood Hits	77	Target Neighborhood Hits	364	Shared Neighborhood Hits	62
SwissProt Accessions	O00187, O75754, Q5TEQ5, Q5TER0, Q96QG4, Q9BZH0, Q9H498, Q9H499, Q9UBP3, Q9ULC7, Q9UMV3, Q9Y270	Gene names	MASP2
Domain Architecture
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

MASP2_MOUSE
θ value	1.87187e-05 (rank : 41)	NC score	0.263019 (rank : 55)
Query Neighborhood Hits	77	Target Neighborhood Hits	382	Shared Neighborhood Hits	64
SwissProt Accessions	Q91WP0, Q9QXA4, Q9QXD2, Q9QXD5, Q9Z338	Gene names	Masp2
Domain Architecture	No domain graphic available
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

MASP1_HUMAN
θ value	2.44474e-05 (rank : 42)	NC score	0.231104 (rank : 59)
Query Neighborhood Hits	77	Target Neighborhood Hits	369	Shared Neighborhood Hits	63
SwissProt Accessions	P48740, O95570, Q9UF09	Gene names	MASP1, CRARF, CRARF1, PRSS5
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) (Mannose-binding protein- associated serine protease) (MASP-1) [Contains: Complement-activating component of Ra-reactive factor heavy chain; Complement-activating component of Ra-reactive factor light chain].

SUSD2_HUMAN
θ value	2.44474e-05 (rank : 43)	NC score	0.479670 (rank : 45)
Query Neighborhood Hits	77	Target Neighborhood Hits	99	Shared Neighborhood Hits	63
SwissProt Accessions	Q9UGT4, Q9H5Y6	Gene names	SUSD2
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 2 precursor.

LYAM1_HUMAN
θ value	5.44631e-05 (rank : 44)	NC score	0.556038 (rank : 39)
Query Neighborhood Hits	77	Target Neighborhood Hits	315	Shared Neighborhood Hits	63
SwissProt Accessions	P14151, P15023	Gene names	SELL, LNHR, LYAM1
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Leukocyte surface antigen Leu-8) (TQ1) (gp90-MEL) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

PAP2_HUMAN
θ value	5.44631e-05 (rank : 45)	NC score	0.472784 (rank : 46)
Query Neighborhood Hits	77	Target Neighborhood Hits	106	Shared Neighborhood Hits	51
SwissProt Accessions	Q9BXP8, Q96PH7, Q96PH8, Q9H4C9	Gene names	PAPPA2
Domain Architecture	No domain graphic available
Description	Pappalysin-2 precursor (EC 3.4.24.-) (Pregnancy-associated plasma protein-A2) (PAPP-A2) (Pregnancy-associated plasma protein-E1) (PAPP- E).

PERT_MOUSE
θ value	7.1131e-05 (rank : 46)	NC score	0.224090 (rank : 61)
Query Neighborhood Hits	77	Target Neighborhood Hits	221	Shared Neighborhood Hits	58
SwissProt Accessions	P35419, Q8C8B1	Gene names	Tpo
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

SUSD4_MOUSE
θ value	9.29e-05 (rank : 47)	NC score	0.708080 (rank : 31)
Query Neighborhood Hits	77	Target Neighborhood Hits	122	Shared Neighborhood Hits	61
SwissProt Accessions	Q8BH32, Q8VC43	Gene names	Susd4
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 4 precursor.

CO7_HUMAN
θ value	0.000158464 (rank : 48)	NC score	0.384559 (rank : 49)
Query Neighborhood Hits	77	Target Neighborhood Hits	278	Shared Neighborhood Hits	50
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

CO6_HUMAN
θ value	0.000461057 (rank : 49)	NC score	0.335368 (rank : 51)
Query Neighborhood Hits	77	Target Neighborhood Hits	331	Shared Neighborhood Hits	62
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

SUSD4_HUMAN
θ value	0.000461057 (rank : 50)	NC score	0.704558 (rank : 33)
Query Neighborhood Hits	77	Target Neighborhood Hits	88	Shared Neighborhood Hits	61
SwissProt Accessions	Q5VX71, Q6UX62, Q9BSR0, Q9NWG0	Gene names	SUSD4
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 4 precursor.

MASP1_MOUSE
θ value	0.000602161 (rank : 51)	NC score	0.225083 (rank : 60)
Query Neighborhood Hits	77	Target Neighborhood Hits	364	Shared Neighborhood Hits	59
SwissProt Accessions	P98064	Gene names	Masp1, Crarf
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) [Contains: Complement- activating component of Ra-reactive factor heavy chain; Complement- activating component of Ra-reactive factor light chain].

PAPPA_MOUSE
θ value	0.000786445 (rank : 52)	NC score	0.540518 (rank : 40)
Query Neighborhood Hits	77	Target Neighborhood Hits	153	Shared Neighborhood Hits	56
SwissProt Accessions	Q8R4K8, Q80VW3, Q80YY1, Q8K423, Q8R4K7, Q9ES06, Q9JK57	Gene names	Pappa
Domain Architecture	No domain graphic available
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

FHR4_HUMAN
θ value	0.00228821 (rank : 53)	NC score	0.653837 (rank : 37)
Query Neighborhood Hits	77	Target Neighborhood Hits	75	Shared Neighborhood Hits	59
SwissProt Accessions	Q92496, Q9UJY6	Gene names	CFHL4, FHR4
Domain Architecture
Description	Complement factor H-related protein 4 precursor (FHR-4).

C1R_HUMAN
θ value	0.00298849 (rank : 54)	NC score	0.210399 (rank : 67)
Query Neighborhood Hits	77	Target Neighborhood Hits	364	Shared Neighborhood Hits	54
SwissProt Accessions	P00736, Q8J012	Gene names	C1R
Domain Architecture
Description	Complement C1r subcomponent precursor (EC 3.4.21.41) (Complement component 1, r subcomponent) [Contains: Complement C1r subcomponent heavy chain; Complement C1r subcomponent light chain].

GABR1_HUMAN
θ value	0.0148317 (rank : 55)	NC score	0.324147 (rank : 52)
Query Neighborhood Hits	77	Target Neighborhood Hits	142	Shared Neighborhood Hits	48
SwissProt Accessions	Q9UBS5, O95375, O95468, O95975, O96022, Q86W60, Q9UQQ0	Gene names	GABBR1, GPRC3A
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 1 precursor (GABA-B receptor 1) (GABA-B-R1) (Gb1).

GABR1_MOUSE
θ value	0.0148317 (rank : 56)	NC score	0.322406 (rank : 53)
Query Neighborhood Hits	77	Target Neighborhood Hits	139	Shared Neighborhood Hits	48
SwissProt Accessions	Q9WV18, Q9WU48, Q9WV15, Q9WV16, Q9WV17	Gene names	Gabbr1
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 1 precursor (GABA-B receptor 1) (GABA-B-R1) (Gb1).

PAPPA_HUMAN
θ value	0.0193708 (rank : 57)	NC score	0.540347 (rank : 41)
Query Neighborhood Hits	77	Target Neighborhood Hits	161	Shared Neighborhood Hits	57
SwissProt Accessions	Q13219, Q08371, Q68G52, Q9UDK7	Gene names	PAPPA
Domain Architecture
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

C1RB_MOUSE
θ value	0.0431538 (rank : 58)	NC score	0.214731 (rank : 66)
Query Neighborhood Hits	77	Target Neighborhood Hits	380	Shared Neighborhood Hits	54
SwissProt Accessions	Q8CFG9	Gene names	C1rb, C1r
Domain Architecture	No domain graphic available
Description	Complement C1r-B subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-B subcomponent) [Contains: Complement C1r-B subcomponent heavy chain; Complement C1r-B subcomponent light chain].

LAMB2_HUMAN
θ value	0.0431538 (rank : 59)	NC score	0.037172 (rank : 221)
Query Neighborhood Hits	77	Target Neighborhood Hits	692	Shared Neighborhood Hits	19
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

PERT_HUMAN
θ value	0.0431538 (rank : 60)	NC score	0.200483 (rank : 68)
Query Neighborhood Hits	77	Target Neighborhood Hits	221	Shared Neighborhood Hits	57
SwissProt Accessions	P07202, P09934, P09935, Q8IUL0, Q8NF94, Q8NF95, Q8NF96, Q8NF97, Q8TCI9	Gene names	TPO
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

C1S_HUMAN
θ value	0.0563607 (rank : 61)	NC score	0.241980 (rank : 58)
Query Neighborhood Hits	77	Target Neighborhood Hits	359	Shared Neighborhood Hits	60
SwissProt Accessions	P09871, Q9UCU7, Q9UCU8, Q9UCU9, Q9UCV0, Q9UCV1, Q9UCV2, Q9UCV3, Q9UCV4, Q9UCV5, Q9UM14	Gene names	C1S
Domain Architecture
Description	Complement C1s subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s subcomponent heavy chain; Complement C1s subcomponent light chain].

LAMB2_MOUSE
θ value	0.0961366 (rank : 62)	NC score	0.038964 (rank : 220)
Query Neighborhood Hits	77	Target Neighborhood Hits	722	Shared Neighborhood Hits	19
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

C1RA_MOUSE
θ value	0.21417 (rank : 63)	NC score	0.216233 (rank : 65)
Query Neighborhood Hits	77	Target Neighborhood Hits	379	Shared Neighborhood Hits	55
SwissProt Accessions	Q8CG16, Q99KI6, Q9ET60	Gene names	C1ra, C1r
Domain Architecture
Description	Complement C1r-A subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-A subcomponent) [Contains: Complement C1r-A subcomponent heavy chain; Complement C1r-A subcomponent light chain].

SUSD2_MOUSE
θ value	0.21417 (rank : 64)	NC score	0.459025 (rank : 47)
Query Neighborhood Hits	77	Target Neighborhood Hits	104	Shared Neighborhood Hits	61
SwissProt Accessions	Q9DBX3, Q8BY19, Q8BYN0, Q8BYZ3, Q8BYZ9, Q8BZQ4, Q8C179	Gene names	Susd2
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 2 precursor.

SUSD3_HUMAN
θ value	0.365318 (rank : 65)	NC score	0.242700 (rank : 57)
Query Neighborhood Hits	77	Target Neighborhood Hits	32	Shared Neighborhood Hits	28
SwissProt Accessions	Q96L08, Q49AA6, Q6UXV7	Gene names	SUSD3, UNQ9387/PRO34275
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 3.

SUSD3_MOUSE
θ value	0.47712 (rank : 66)	NC score	0.366263 (rank : 50)
Query Neighborhood Hits	77	Target Neighborhood Hits	39	Shared Neighborhood Hits	36
SwissProt Accessions	Q9D176, Q80XL5, Q9CYV1, Q9DA86	Gene names	Susd3
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 3.

SUSD1_HUMAN
θ value	1.06291 (rank : 67)	NC score	0.277699 (rank : 54)
Query Neighborhood Hits	77	Target Neighborhood Hits	285	Shared Neighborhood Hits	58
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

CS1B_MOUSE
θ value	1.38821 (rank : 68)	NC score	0.219060 (rank : 63)
Query Neighborhood Hits	77	Target Neighborhood Hits	361	Shared Neighborhood Hits	60
SwissProt Accessions	Q8CFG8	Gene names	C1sb, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-B subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-B subcomponent heavy chain; Complement C1s-B subcomponent light chain].

LAMA2_HUMAN
θ value	3.0926 (rank : 69)	NC score	0.031161 (rank : 223)
Query Neighborhood Hits	77	Target Neighborhood Hits	1092	Shared Neighborhood Hits	22
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

CS1A_MOUSE
θ value	4.03905 (rank : 70)	NC score	0.217543 (rank : 64)
Query Neighborhood Hits	77	Target Neighborhood Hits	360	Shared Neighborhood Hits	60
SwissProt Accessions	Q8CG14, Q8BJC4, Q8CH28, Q8VBY4	Gene names	C1sa, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-A subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-A subcomponent heavy chain; Complement C1s-A subcomponent light chain].

MYH3_HUMAN
θ value	4.03905 (rank : 71)	NC score	-0.002103 (rank : 225)
Query Neighborhood Hits	77	Target Neighborhood Hits	1660	Shared Neighborhood Hits	6
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

C1QR1_HUMAN
θ value	5.27518 (rank : 72)	NC score	0.039724 (rank : 219)
Query Neighborhood Hits	77	Target Neighborhood Hits	493	Shared Neighborhood Hits	29
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

FBLN3_MOUSE
θ value	6.88961 (rank : 73)	NC score	0.034801 (rank : 222)
Query Neighborhood Hits	77	Target Neighborhood Hits	279	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

LAMB1_MOUSE
θ value	6.88961 (rank : 74)	NC score	0.028551 (rank : 224)
Query Neighborhood Hits	77	Target Neighborhood Hits	919	Shared Neighborhood Hits	18
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

PROS_HUMAN
θ value	6.88961 (rank : 75)	NC score	0.043231 (rank : 218)
Query Neighborhood Hits	77	Target Neighborhood Hits	340	Shared Neighborhood Hits	29
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

ATRN_MOUSE
θ value	8.99809 (rank : 76)	NC score	0.090371 (rank : 117)
Query Neighborhood Hits	77	Target Neighborhood Hits	519	Shared Neighborhood Hits	22
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

FBLN5_MOUSE
θ value	8.99809 (rank : 77)	NC score	0.046182 (rank : 217)
Query Neighborhood Hits	77	Target Neighborhood Hits	317	Shared Neighborhood Hits	30
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

ACRO_HUMAN
θ value	θ > 10 (rank : 78)	NC score	0.053211 (rank : 180)
Query Neighborhood Hits	77	Target Neighborhood Hits	291	Shared Neighborhood Hits	15
SwissProt Accessions	P10323, Q6ICK2	Gene names	ACR, ACRS
Domain Architecture
Description	Acrosin precursor (EC 3.4.21.10) [Contains: Acrosin light chain; Acrosin heavy chain].

ACRO_MOUSE
θ value	θ > 10 (rank : 79)	NC score	0.053118 (rank : 181)
Query Neighborhood Hits	77	Target Neighborhood Hits	185	Shared Neighborhood Hits	14
SwissProt Accessions	P23578	Gene names	Acr
Domain Architecture
Description	Acrosin precursor (EC 3.4.21.10) [Contains: Acrosin light chain; Acrosin heavy chain].

ASGR1_MOUSE
θ value	θ > 10 (rank : 80)	NC score	0.052654 (rank : 187)
Query Neighborhood Hits	77	Target Neighborhood Hits	135	Shared Neighborhood Hits	8
SwissProt Accessions	P34927, Q64363	Gene names	Asgr1, Asgr-1
Domain Architecture
Description	Asialoglycoprotein receptor 1 (ASGPR 1) (ASGP-R 1) (Hepatic lectin 1) (MHL-1).

ASGR2_HUMAN
θ value	θ > 10 (rank : 81)	NC score	0.052995 (rank : 185)
Query Neighborhood Hits	77	Target Neighborhood Hits	121	Shared Neighborhood Hits	6
SwissProt Accessions	P07307, O00448, Q03969	Gene names	ASGR2
Domain Architecture
Description	Asialoglycoprotein receptor 2 (ASGP-R 2) (ASGPR 2) (Hepatic lectin H2).

ASGR2_MOUSE
θ value	θ > 10 (rank : 82)	NC score	0.055804 (rank : 160)
Query Neighborhood Hits	77	Target Neighborhood Hits	123	Shared Neighborhood Hits	8
SwissProt Accessions	P24721	Gene names	Asgr2, Asgr-2
Domain Architecture
Description	Asialoglycoprotein receptor 2 (ASGP-R 2) (ASGPR 2) (Hepatic lectin 2) (MHL-2).

ATRN_HUMAN
θ value	θ > 10 (rank : 83)	NC score	0.090874 (rank : 116)
Query Neighborhood Hits	77	Target Neighborhood Hits	525	Shared Neighborhood Hits	20
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

BMP1_HUMAN
θ value	θ > 10 (rank : 84)	NC score	0.164919 (rank : 74)
Query Neighborhood Hits	77	Target Neighborhood Hits	233	Shared Neighborhood Hits	27
SwissProt Accessions	P13497, Q13292, Q13872, Q14874, Q99421, Q99422, Q99423, Q9UL38	Gene names	BMP1, PCOLC
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

BMP1_MOUSE
θ value	θ > 10 (rank : 85)	NC score	0.165318 (rank : 73)
Query Neighborhood Hits	77	Target Neighborhood Hits	236	Shared Neighborhood Hits	27
SwissProt Accessions	P98063	Gene names	Bmp1
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

BSSP4_HUMAN
θ value	θ > 10 (rank : 86)	NC score	0.053694 (rank : 176)
Query Neighborhood Hits	77	Target Neighborhood Hits	176	Shared Neighborhood Hits	14
SwissProt Accessions	Q9GZN4, O43342, Q6UXE0	Gene names	PRSS22, BSSP4, PRSS26
Domain Architecture
Description	Brain-specific serine protease 4 precursor (EC 3.4.21.-) (BSSP-4) (Serine protease 22) (Tryptase epsilon).

BSSP4_MOUSE
θ value	θ > 10 (rank : 87)	NC score	0.058036 (rank : 148)
Query Neighborhood Hits	77	Target Neighborhood Hits	179	Shared Neighborhood Hits	14
SwissProt Accessions	Q9ER10	Gene names	Prss22, Bssp4, Prss26
Domain Architecture
Description	Brain-specific serine protease 4 precursor (EC 3.4.21.-) (BSSP-4) (Serine protease 22) (Tryptase epsilon).

C209A_MOUSE
θ value	θ > 10 (rank : 88)	NC score	0.053009 (rank : 184)
Query Neighborhood Hits	77	Target Neighborhood Hits	117	Shared Neighborhood Hits	7
SwissProt Accessions	Q91ZX1, Q3TAT9, Q91ZW5	Gene names	Cd209a, Cire
Domain Architecture
Description	CD209 antigen-like protein A (Dendritic cell-specific ICAM-3-grabbing nonintegrin) (DC-SIGN).

C209C_MOUSE
θ value	θ > 10 (rank : 89)	NC score	0.050499 (rank : 208)
Query Neighborhood Hits	77	Target Neighborhood Hits	114	Shared Neighborhood Hits	6
SwissProt Accessions	Q91ZW9	Gene names	Cd209c
Domain Architecture
Description	CD209 antigen-like protein C (DC-SIGN-related protein 2) (DC-SIGNR2).

C209E_MOUSE
θ value	θ > 10 (rank : 90)	NC score	0.052029 (rank : 193)
Query Neighborhood Hits	77	Target Neighborhood Hits	117	Shared Neighborhood Hits	7
SwissProt Accessions	Q91ZW7	Gene names	Cd209e
Domain Architecture
Description	CD209 antigen-like protein E (DC-SIGN-related protein 4) (DC-SIGNR4).

CFAI_HUMAN
θ value	θ > 10 (rank : 91)	NC score	0.053453 (rank : 179)
Query Neighborhood Hits	77	Target Neighborhood Hits	289	Shared Neighborhood Hits	19
SwissProt Accessions	P05156, O60442	Gene names	CFI, IF
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

CFAI_MOUSE
θ value	θ > 10 (rank : 92)	NC score	0.051640 (rank : 197)
Query Neighborhood Hits	77	Target Neighborhood Hits	290	Shared Neighborhood Hits	18
SwissProt Accessions	Q61129, Q9WU07	Gene names	Cfi, If
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

CLC10_HUMAN
θ value	θ > 10 (rank : 93)	NC score	0.057325 (rank : 150)
Query Neighborhood Hits	77	Target Neighborhood Hits	134	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IUN9, Q14538, Q6PIW3	Gene names	CLEC10A, CLECSF14, HML
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 10 member A (C-type lectin superfamily member 14) (Macrophage lectin 2) (CD301 antigen).

CLC4A_MOUSE
θ value	θ > 10 (rank : 94)	NC score	0.056713 (rank : 156)
Query Neighborhood Hits	77	Target Neighborhood Hits	103	Shared Neighborhood Hits	7
SwissProt Accessions	Q9QZ15, Q4VA33	Gene names	Clec4a, Clec4a2, Clecsf6, Dcir
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 4 member A (C-type lectin superfamily member 6) (Dendritic cell immunoreceptor).

CLC4C_HUMAN
θ value	θ > 10 (rank : 95)	NC score	0.051031 (rank : 203)
Query Neighborhood Hits	77	Target Neighborhood Hits	111	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WTT0, Q3T1C3, Q6UXS8, Q8WXX8	Gene names	CLEC4C, BDCA2, CLECSF11, CLECSF7, DLEC, HECL
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 4 member C (C-type lectin superfamily member 7) (Blood dendritic cell antigen 2 protein) (BDCA-2) (Dendritic lectin) (CD303 antigen).

CLC4E_HUMAN
θ value	θ > 10 (rank : 96)	NC score	0.050191 (rank : 213)
Query Neighborhood Hits	77	Target Neighborhood Hits	104	Shared Neighborhood Hits	7
SwissProt Accessions	Q9ULY5	Gene names	CLEC4E, CLECSF9, MINCLE
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 4 member E (C-type lectin superfamily member 9) (Macrophage-inducible C-type lectin).

CLC4E_MOUSE
θ value	θ > 10 (rank : 97)	NC score	0.053961 (rank : 173)
Query Neighborhood Hits	77	Target Neighborhood Hits	113	Shared Neighborhood Hits	7
SwissProt Accessions	Q9R0Q8	Gene names	Clec4e, Clecsf9, Mincle
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 4 member E (C-type lectin superfamily member 9) (Macrophage-inducible C-type lectin).

CLC4G_MOUSE
θ value	θ > 10 (rank : 98)	NC score	0.052488 (rank : 188)
Query Neighborhood Hits	77	Target Neighborhood Hits	155	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BNX1, Q5I0T7, Q8R188	Gene names	Clec4g
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 4 member G.

CLC4K_HUMAN
θ value	θ > 10 (rank : 99)	NC score	0.065449 (rank : 136)
Query Neighborhood Hits	77	Target Neighborhood Hits	172	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UJ71	Gene names	CD207, CLEC4K
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 4 member K (Langerin) (CD207 antigen).

CLC4K_MOUSE
θ value	θ > 10 (rank : 100)	NC score	0.063924 (rank : 140)
Query Neighborhood Hits	77	Target Neighborhood Hits	165	Shared Neighborhood Hits	7
SwissProt Accessions	Q8VBX4, Q8R442	Gene names	Cd207, Clec4k
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 4 member K (Langerin) (CD207 antigen).

CLCR_HUMAN
θ value	θ > 10 (rank : 101)	NC score	0.050175 (rank : 214)
Query Neighborhood Hits	77	Target Neighborhood Hits	177	Shared Neighborhood Hits	14
SwissProt Accessions	Q99895, O00765, Q9NUH5	Gene names	CTRC, CLCR
Domain Architecture
Description	Caldecrin precursor (EC 3.4.21.2) (Chymotrypsin C).

CORIN_HUMAN
θ value	θ > 10 (rank : 102)	NC score	0.050918 (rank : 204)
Query Neighborhood Hits	77	Target Neighborhood Hits	453	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y5Q5, Q9UHY2	Gene names	CORIN, CRN, TMPRSS10
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Heart-specific serine proteinase ATC2) (Transmembrane protease, serine 10).

CSPG2_HUMAN
θ value	θ > 10 (rank : 103)	NC score	0.102119 (rank : 110)
Query Neighborhood Hits	77	Target Neighborhood Hits	681	Shared Neighborhood Hits	49
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

CSPG2_MOUSE
θ value	θ > 10 (rank : 104)	NC score	0.102323 (rank : 108)
Query Neighborhood Hits	77	Target Neighborhood Hits	711	Shared Neighborhood Hits	49
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

CSPG3_HUMAN
θ value	θ > 10 (rank : 105)	NC score	0.110222 (rank : 105)
Query Neighborhood Hits	77	Target Neighborhood Hits	676	Shared Neighborhood Hits	55
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

CSPG3_MOUSE
θ value	θ > 10 (rank : 106)	NC score	0.118621 (rank : 95)
Query Neighborhood Hits	77	Target Neighborhood Hits	657	Shared Neighborhood Hits	55
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

CUBN_HUMAN
θ value	θ > 10 (rank : 107)	NC score	0.138396 (rank : 81)
Query Neighborhood Hits	77	Target Neighborhood Hits	482	Shared Neighborhood Hits	35
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

CUBN_MOUSE
θ value	θ > 10 (rank : 108)	NC score	0.127644 (rank : 84)
Query Neighborhood Hits	77	Target Neighborhood Hits	477	Shared Neighborhood Hits	34
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

CUZD1_HUMAN
θ value	θ > 10 (rank : 109)	NC score	0.131434 (rank : 82)
Query Neighborhood Hits	77	Target Neighborhood Hits	89	Shared Neighborhood Hits	16
SwissProt Accessions	Q86UP6, Q7Z660, Q7Z661, Q86SG1, Q86UP5, Q9HAR7	Gene names	CUZD1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Transmembrane protein UO-44).

CUZD1_MOUSE
θ value	θ > 10 (rank : 110)	NC score	0.121131 (rank : 90)
Query Neighborhood Hits	77	Target Neighborhood Hits	91	Shared Neighborhood Hits	16
SwissProt Accessions	P70412, Q9CTZ7	Gene names	Cuzd1, Itmap1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Integral membrane-associated protein 1).

DCBD1_HUMAN
θ value	θ > 10 (rank : 111)	NC score	0.086703 (rank : 122)
Query Neighborhood Hits	77	Target Neighborhood Hits	110	Shared Neighborhood Hits	15
SwissProt Accessions	Q8N8Z6, Q5H992, Q8IYK5, Q8N7L9, Q96NH2	Gene names	DCBLD1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

DCBD1_MOUSE
θ value	θ > 10 (rank : 112)	NC score	0.112603 (rank : 101)
Query Neighborhood Hits	77	Target Neighborhood Hits	89	Shared Neighborhood Hits	15
SwissProt Accessions	Q9D4J3, Q8R327, Q9D696	Gene names	Dcbld1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

DCBD2_HUMAN
θ value	θ > 10 (rank : 113)	NC score	0.094881 (rank : 114)
Query Neighborhood Hits	77	Target Neighborhood Hits	118	Shared Neighborhood Hits	16
SwissProt Accessions	Q96PD2, Q8N6M4, Q8TDX2	Gene names	DCBLD2, CLCP1, ESDN
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein) (CUB, LCCL and coagulation factor V/VIII-homology domains protein 1).

DCBD2_MOUSE
θ value	θ > 10 (rank : 114)	NC score	0.086935 (rank : 121)
Query Neighborhood Hits	77	Target Neighborhood Hits	113	Shared Neighborhood Hits	16
SwissProt Accessions	Q91ZV3, Q8BKI4	Gene names	Dcbld2, Esdn
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein).

DESC4_MOUSE
θ value	θ > 10 (rank : 115)	NC score	0.054506 (rank : 168)
Query Neighborhood Hits	77	Target Neighborhood Hits	176	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BZ10, Q8BZ04	Gene names	Desc4
Domain Architecture	No domain graphic available
Description	Serine protease DESC4 precursor (EC 3.4.21.-) [Contains: Serine protease DESC4 non-catalytic chain; Serine protease DESC4 catalytic chain].

DMBT1_HUMAN
θ value	θ > 10 (rank : 116)	NC score	0.092954 (rank : 115)
Query Neighborhood Hits	77	Target Neighborhood Hits	152	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UGM3, Q59EX0, Q5JR26, Q6MZN4, Q96DU4, Q9UGM2, Q9UJ57, Q9UKJ4, Q9Y211, Q9Y4V9	Gene names	DMBT1, GP340
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (Glycoprotein 340) (Gp-340) (Surfactant pulmonary-associated D-binding protein).

DMBT1_MOUSE
θ value	θ > 10 (rank : 117)	NC score	0.113473 (rank : 99)
Query Neighborhood Hits	77	Target Neighborhood Hits	134	Shared Neighborhood Hits	16
SwissProt Accessions	Q60997, Q80YC6, Q9JMJ9	Gene names	Dmbt1, Crpd
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (CRP-ductin) (Vomeroglandin).

ENTK_HUMAN
θ value	θ > 10 (rank : 118)	NC score	0.083200 (rank : 125)
Query Neighborhood Hits	77	Target Neighborhood Hits	310	Shared Neighborhood Hits	22
SwissProt Accessions	P98073	Gene names	PRSS7, ENTK
Domain Architecture
Description	Enteropeptidase precursor (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

ENTK_MOUSE
θ value	θ > 10 (rank : 119)	NC score	0.085649 (rank : 123)
Query Neighborhood Hits	77	Target Neighborhood Hits	338	Shared Neighborhood Hits	21
SwissProt Accessions	P97435	Gene names	Prss7, Entk
Domain Architecture
Description	Enteropeptidase (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

FA10_HUMAN
θ value	θ > 10 (rank : 120)	NC score	0.078037 (rank : 129)
Query Neighborhood Hits	77	Target Neighborhood Hits	431	Shared Neighborhood Hits	29
SwissProt Accessions	P00742, Q14340	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) (Stuart- Prower factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

FA10_MOUSE
θ value	θ > 10 (rank : 121)	NC score	0.077410 (rank : 130)
Query Neighborhood Hits	77	Target Neighborhood Hits	435	Shared Neighborhood Hits	29
SwissProt Accessions	O88947, O54740, Q99L32	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

FA11_HUMAN
θ value	θ > 10 (rank : 122)	NC score	0.056798 (rank : 155)
Query Neighborhood Hits	77	Target Neighborhood Hits	178	Shared Neighborhood Hits	14
SwissProt Accessions	P03951, Q9Y495	Gene names	F11
Domain Architecture
Description	Coagulation factor XI precursor (EC 3.4.21.27) (Plasma thromboplastin antecedent) (PTA) (FXI) [Contains: Coagulation factor XIa heavy chain; Coagulation factor XIa light chain].

FA11_MOUSE
θ value	θ > 10 (rank : 123)	NC score	0.055781 (rank : 161)
Query Neighborhood Hits	77	Target Neighborhood Hits	180	Shared Neighborhood Hits	14
SwissProt Accessions	Q91Y47	Gene names	F11
Domain Architecture
Description	Coagulation factor XI precursor (EC 3.4.21.27) (Plasma thromboplastin antecedent) (PTA) (FXI) [Contains: Coagulation factor XIa heavy chain; Coagulation factor XIa light chain].

FA12_HUMAN
θ value	θ > 10 (rank : 124)	NC score	0.052443 (rank : 190)
Query Neighborhood Hits	77	Target Neighborhood Hits	425	Shared Neighborhood Hits	27
SwissProt Accessions	P00748, P78339	Gene names	F12
Domain Architecture
Description	Coagulation factor XII precursor (EC 3.4.21.38) (Hageman factor) (HAF) [Contains: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Beta-factor XIIa part 2; Coagulation factor XIIa light chain].

FA7_HUMAN
θ value	θ > 10 (rank : 125)	NC score	0.064056 (rank : 138)
Query Neighborhood Hits	77	Target Neighborhood Hits	404	Shared Neighborhood Hits	25
SwissProt Accessions	P08709, Q14339, Q5JVF2	Gene names	F7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) (SPCA) (Proconvertin) (Eptacog alfa) [Contains: Factor VII light chain; Factor VII heavy chain].

FA7_MOUSE
θ value	θ > 10 (rank : 126)	NC score	0.059146 (rank : 147)
Query Neighborhood Hits	77	Target Neighborhood Hits	374	Shared Neighborhood Hits	23
SwissProt Accessions	P70375, Q61109	Gene names	F7, Cf7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) [Contains: Factor VII light chain; Factor VII heavy chain].

FA9_HUMAN
θ value	θ > 10 (rank : 127)	NC score	0.065755 (rank : 135)
Query Neighborhood Hits	77	Target Neighborhood Hits	421	Shared Neighborhood Hits	27
SwissProt Accessions	P00740	Gene names	F9
Domain Architecture
Description	Coagulation factor IX precursor (EC 3.4.21.22) (Christmas factor) (Plasma thromboplastin component) (PTC) [Contains: Coagulation factor IXa light chain; Coagulation factor IXa heavy chain].

FCER2_HUMAN
θ value	θ > 10 (rank : 128)	NC score	0.053926 (rank : 174)
Query Neighborhood Hits	77	Target Neighborhood Hits	213	Shared Neighborhood Hits	6
SwissProt Accessions	P06734	Gene names	FCER2, IGEBF
Domain Architecture
Description	Low affinity immunoglobulin epsilon Fc receptor (Lymphocyte IgE receptor) (Fc-epsilon-RII) (BLAST-2) (Immunoglobulin E-binding factor) (CD23 antigen) [Contains: Low affinity immunoglobulin epsilon Fc receptor membrane-bound form; Low affinity immunoglobulin epsilon Fc receptor soluble form].

GP126_HUMAN
θ value	θ > 10 (rank : 129)	NC score	0.081924 (rank : 126)
Query Neighborhood Hits	77	Target Neighborhood Hits	187	Shared Neighborhood Hits	16
SwissProt Accessions	Q86SQ4, Q6MZU7, Q8NC14, Q96JW0	Gene names	GPR126
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 126 precursor.

HABP2_HUMAN
θ value	θ > 10 (rank : 130)	NC score	0.057100 (rank : 152)
Query Neighborhood Hits	77	Target Neighborhood Hits	431	Shared Neighborhood Hits	30
SwissProt Accessions	Q14520, O00663	Gene names	HABP2, HGFAL, PHBP
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) (Hepatocyte growth factor activator-like protein) (Factor VII-activating protease) (Factor seven-activating protease) (FSAP) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

HABP2_MOUSE
θ value	θ > 10 (rank : 131)	NC score	0.050136 (rank : 215)
Query Neighborhood Hits	77	Target Neighborhood Hits	445	Shared Neighborhood Hits	32
SwissProt Accessions	Q8K0D2	Gene names	Habp2, Phbp
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

HEPS_HUMAN
θ value	θ > 10 (rank : 132)	NC score	0.051639 (rank : 198)
Query Neighborhood Hits	77	Target Neighborhood Hits	178	Shared Neighborhood Hits	14
SwissProt Accessions	P05981	Gene names	HPN, TMPRSS1
Domain Architecture
Description	Serine protease hepsin (EC 3.4.21.-) (Transmembrane protease, serine 1) [Contains: Serine protease hepsin non-catalytic chain; Serine protease hepsin catalytic chain].

HEPS_MOUSE
θ value	θ > 10 (rank : 133)	NC score	0.052055 (rank : 192)
Query Neighborhood Hits	77	Target Neighborhood Hits	178	Shared Neighborhood Hits	14
SwissProt Accessions	O35453, Q9CW97	Gene names	Hpn
Domain Architecture
Description	Serine protease hepsin (EC 3.4.21.-) [Contains: Serine protease hepsin non-catalytic chain; Serine protease hepsin catalytic chain].

HPTR_HUMAN
θ value	θ > 10 (rank : 134)	NC score	0.078274 (rank : 128)
Query Neighborhood Hits	77	Target Neighborhood Hits	166	Shared Neighborhood Hits	15
SwissProt Accessions	P00739, Q7LE20, Q92658, Q92659, Q9ULB0	Gene names	HPR
Domain Architecture
Description	Haptoglobin-related protein precursor.

HPT_HUMAN
θ value	θ > 10 (rank : 135)	NC score	0.112793 (rank : 100)
Query Neighborhood Hits	77	Target Neighborhood Hits	184	Shared Neighborhood Hits	32
SwissProt Accessions	P00738, P00737, Q2PP15, Q3B7J0, Q6LBY9	Gene names	HP
Domain Architecture
Description	Haptoglobin precursor [Contains: Haptoglobin alpha chain; Haptoglobin beta chain].

HPT_MOUSE
θ value	θ > 10 (rank : 136)	NC score	0.080337 (rank : 127)
Query Neighborhood Hits	77	Target Neighborhood Hits	178	Shared Neighborhood Hits	19
SwissProt Accessions	Q61646	Gene names	Hp
Domain Architecture
Description	Haptoglobin precursor [Contains: Haptoglobin alpha chain; Haptoglobin beta chain].

IL2RA_HUMAN
θ value	θ > 10 (rank : 137)	NC score	0.102111 (rank : 111)
Query Neighborhood Hits	77	Target Neighborhood Hits	32	Shared Neighborhood Hits	18
SwissProt Accessions	P01589	Gene names	IL2RA
Domain Architecture
Description	Interleukin-2 receptor alpha chain precursor (IL-2 receptor alpha subunit) (IL-2-RA) (IL2-RA) (p55) (TAC antigen) (CD25 antigen).

K0247_HUMAN
θ value	θ > 10 (rank : 138)	NC score	0.223899 (rank : 62)
Query Neighborhood Hits	77	Target Neighborhood Hits	42	Shared Neighborhood Hits	29
SwissProt Accessions	Q92537	Gene names	KIAA0247
Domain Architecture	No domain graphic available
Description	Protein KIAA0247 precursor.

K1KB9_MOUSE
θ value	θ > 10 (rank : 139)	NC score	0.050113 (rank : 216)
Query Neighborhood Hits	77	Target Neighborhood Hits	176	Shared Neighborhood Hits	14
SwissProt Accessions	P15949	Gene names	Klk1b9, Egfbp3, Klk-9, Klk9
Domain Architecture
Description	Kallikrein 1-related peptidase b9 precursor (EC 3.4.21.35) (Tissue kallikrein-9) (Glandular kallikrein K9) (mGK-9) (Epidermal growth factor-binding protein type C) (EGF-BP C).

KLKB1_HUMAN
θ value	θ > 10 (rank : 140)	NC score	0.054527 (rank : 167)
Query Neighborhood Hits	77	Target Neighborhood Hits	183	Shared Neighborhood Hits	14
SwissProt Accessions	P03952	Gene names	KLKB1, KLK3
Domain Architecture
Description	Plasma kallikrein precursor (EC 3.4.21.34) (Plasma prekallikrein) (Kininogenin) (Fletcher factor) [Contains: Plasma kallikrein heavy chain; Plasma kallikrein light chain].

KLKB1_MOUSE
θ value	θ > 10 (rank : 141)	NC score	0.054634 (rank : 166)
Query Neighborhood Hits	77	Target Neighborhood Hits	177	Shared Neighborhood Hits	14
SwissProt Accessions	P26262	Gene names	Klkb1, Klk3, Pk
Domain Architecture
Description	Plasma kallikrein precursor (EC 3.4.21.34) (Plasma prekallikrein) (Kininogenin) (Fletcher factor) [Contains: Plasma kallikrein heavy chain; Plasma kallikrein light chain].

KREM1_HUMAN
θ value	θ > 10 (rank : 142)	NC score	0.109701 (rank : 106)
Query Neighborhood Hits	77	Target Neighborhood Hits	90	Shared Neighborhood Hits	16
SwissProt Accessions	Q96MU8, Q5TIB9, Q6P3X6, Q9BY70, Q9UGS5, Q9UGU1	Gene names	KREMEN1, KREMEN, KRM1
Domain Architecture
Description	Kremen protein 1 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 1) (Dickkopf receptor).

KREM1_MOUSE
θ value	θ > 10 (rank : 143)	NC score	0.111455 (rank : 103)
Query Neighborhood Hits	77	Target Neighborhood Hits	92	Shared Neighborhood Hits	16
SwissProt Accessions	Q99N43	Gene names	Kremen1, Kremen
Domain Architecture
Description	Kremen protein 1 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 1) (Dickkopf receptor).

KREM2_HUMAN
θ value	θ > 10 (rank : 144)	NC score	0.110896 (rank : 104)
Query Neighborhood Hits	77	Target Neighborhood Hits	93	Shared Neighborhood Hits	16
SwissProt Accessions	Q8NCW0, Q8N2J4, Q8NCW1, Q96GL8, Q9BTP9	Gene names	KREMEN2, KRM2
Domain Architecture
Description	Kremen protein 2 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 2) (Dickkopf receptor 2).

KREM2_MOUSE
θ value	θ > 10 (rank : 145)	NC score	0.100006 (rank : 112)
Query Neighborhood Hits	77	Target Neighborhood Hits	90	Shared Neighborhood Hits	14
SwissProt Accessions	Q8K1S7	Gene names	Kremen2
Domain Architecture
Description	Kremen protein 2 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 2) (Dickkopf receptor 2).

LRP12_HUMAN
θ value	θ > 10 (rank : 146)	NC score	0.118827 (rank : 94)
Query Neighborhood Hits	77	Target Neighborhood Hits	205	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y561	Gene names	LRP12, ST7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor (Suppressor of tumorigenicity protein 7).

LRP12_MOUSE
θ value	θ > 10 (rank : 147)	NC score	0.119037 (rank : 93)
Query Neighborhood Hits	77	Target Neighborhood Hits	180	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BUJ9, Q8BWM9	Gene names	Lrp12
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor.

LRP3_HUMAN
θ value	θ > 10 (rank : 148)	NC score	0.087664 (rank : 118)
Query Neighborhood Hits	77	Target Neighborhood Hits	280	Shared Neighborhood Hits	23
SwissProt Accessions	O75074	Gene names	LRP3
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 3 precursor (hLRp105).

LTBP2_HUMAN
θ value	θ > 10 (rank : 149)	NC score	0.051482 (rank : 200)
Query Neighborhood Hits	77	Target Neighborhood Hits	552	Shared Neighborhood Hits	39
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

MCPT6_MOUSE
θ value	θ > 10 (rank : 150)	NC score	0.051346 (rank : 201)
Query Neighborhood Hits	77	Target Neighborhood Hits	175	Shared Neighborhood Hits	14
SwissProt Accessions	P21845, Q61962	Gene names	Mcpt6
Domain Architecture
Description	Mast cell protease 6 precursor (EC 3.4.21.59) (MMCP-6) (Tryptase).

MFRP_HUMAN
θ value	θ > 10 (rank : 151)	NC score	0.139059 (rank : 80)
Query Neighborhood Hits	77	Target Neighborhood Hits	165	Shared Neighborhood Hits	17
SwissProt Accessions	Q9BY79, Q335M3, Q96DQ9	Gene names	MFRP
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

MFRP_MOUSE
θ value	θ > 10 (rank : 152)	NC score	0.144799 (rank : 78)
Query Neighborhood Hits	77	Target Neighborhood Hits	166	Shared Neighborhood Hits	17
SwissProt Accessions	Q8K480, Q8BPP4	Gene names	Mfrp
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

MMGL_MOUSE
θ value	θ > 10 (rank : 153)	NC score	0.054247 (rank : 169)
Query Neighborhood Hits	77	Target Neighborhood Hits	270	Shared Neighborhood Hits	9
SwissProt Accessions	P49300	Gene names	Mgl1, Mgl
Domain Architecture
Description	Macrophage asialoglycoprotein-binding protein 1 (M-ASGP-BP) (Macrophage galactose/N-acetylgalactosamine-specific lectin) (MMGL).

MRC1_HUMAN
θ value	θ > 10 (rank : 154)	NC score	0.051566 (rank : 199)
Query Neighborhood Hits	77	Target Neighborhood Hits	157	Shared Neighborhood Hits	8
SwissProt Accessions	P22897	Gene names	MRC1
Domain Architecture
Description	Macrophage mannose receptor 1 precursor (MMR) (CD206 antigen).

NETO1_HUMAN
θ value	θ > 10 (rank : 155)	NC score	0.119599 (rank : 91)
Query Neighborhood Hits	77	Target Neighborhood Hits	110	Shared Neighborhood Hits	18
SwissProt Accessions	Q8TDF5, Q86W85, Q8ND78, Q8TDF4	Gene names	NETO1, BTCL1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

NETO1_MOUSE
θ value	θ > 10 (rank : 156)	NC score	0.119474 (rank : 92)
Query Neighborhood Hits	77	Target Neighborhood Hits	109	Shared Neighborhood Hits	18
SwissProt Accessions	Q8R4I7, Q80X39, Q8C4S3, Q8CCM2	Gene names	Neto1, Btcl1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

NETO2_HUMAN
θ value	θ > 10 (rank : 157)	NC score	0.116709 (rank : 96)
Query Neighborhood Hits	77	Target Neighborhood Hits	109	Shared Neighborhood Hits	18
SwissProt Accessions	Q8NC67, Q7Z381, Q8ND51, Q96SP4, Q9NVY8	Gene names	NETO2, BTCL2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

NETO2_MOUSE
θ value	θ > 10 (rank : 158)	NC score	0.115382 (rank : 97)
Query Neighborhood Hits	77	Target Neighborhood Hits	113	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BNJ6, Q5VM49, Q8C4Q8	Gene names	Neto2, Btcl2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

NRP1_HUMAN
θ value	θ > 10 (rank : 159)	NC score	0.112197 (rank : 102)
Query Neighborhood Hits	77	Target Neighborhood Hits	119	Shared Neighborhood Hits	16
SwissProt Accessions	O14786, O60461, Q96IH5	Gene names	NRP1, NRP, VEGF165R
Domain Architecture
Description	Neuropilin-1 precursor (Vascular endothelial cell growth factor 165 receptor) (CD304 antigen).

NRP1_MOUSE
θ value	θ > 10 (rank : 160)	NC score	0.114502 (rank : 98)
Query Neighborhood Hits	77	Target Neighborhood Hits	120	Shared Neighborhood Hits	16
SwissProt Accessions	P97333	Gene names	Nrp1, Nrp
Domain Architecture
Description	Neuropilin-1 precursor (A5 protein).

NRP2_HUMAN
θ value	θ > 10 (rank : 161)	NC score	0.125513 (rank : 88)
Query Neighborhood Hits	77	Target Neighborhood Hits	120	Shared Neighborhood Hits	16
SwissProt Accessions	O60462, O14820, O14821	Gene names	NRP2, VEGF165R2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

NRP2_MOUSE
θ value	θ > 10 (rank : 162)	NC score	0.127187 (rank : 86)
Query Neighborhood Hits	77	Target Neighborhood Hits	113	Shared Neighborhood Hits	16
SwissProt Accessions	O35375, O35373, O35374, O35376, O35377, O35378	Gene names	Nrp2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

PCOC1_HUMAN
θ value	θ > 10 (rank : 163)	NC score	0.158600 (rank : 75)
Query Neighborhood Hits	77	Target Neighborhood Hits	146	Shared Neighborhood Hits	16
SwissProt Accessions	Q15113, O14550	Gene names	PCOLCE, PCPE1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein).

PCOC1_MOUSE
θ value	θ > 10 (rank : 164)	NC score	0.157349 (rank : 76)
Query Neighborhood Hits	77	Target Neighborhood Hits	100	Shared Neighborhood Hits	16
SwissProt Accessions	Q61398, O35113	Gene names	Pcolce, Pcpe1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein) (P14).

PCOC2_HUMAN
θ value	θ > 10 (rank : 165)	NC score	0.147038 (rank : 77)
Query Neighborhood Hits	77	Target Neighborhood Hits	73	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UKZ9, Q9BRH3	Gene names	PCOLCE2, PCPE2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

PCOC2_MOUSE
θ value	θ > 10 (rank : 166)	NC score	0.143760 (rank : 79)
Query Neighborhood Hits	77	Target Neighborhood Hits	73	Shared Neighborhood Hits	16
SwissProt Accessions	Q8R4W6, Q3V1K6, Q9CX06	Gene names	Pcolce2, Pcpe2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

PDGFD_HUMAN
θ value	θ > 10 (rank : 167)	NC score	0.128061 (rank : 83)
Query Neighborhood Hits	77	Target Neighborhood Hits	74	Shared Neighborhood Hits	15
SwissProt Accessions	Q9GZP0, Q9BWV5	Gene names	PDGFD, IEGF, SCDGFB
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor D precursor (PDGF D) (Iris-expressed growth factor) (Spinal cord-derived growth factor B) (SCDGF-B).

PDGFD_MOUSE
θ value	θ > 10 (rank : 168)	NC score	0.122316 (rank : 89)
Query Neighborhood Hits	77	Target Neighborhood Hits	72	Shared Neighborhood Hits	14
SwissProt Accessions	Q925I7, Q3URF6, Q8K2L3, Q9D1L8	Gene names	Pdgfd, Scdgfb
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor chain precursor (PDGF D) (Spinal cord- derived growth factor B) (SCDGF-B).

PGCA_HUMAN
θ value	θ > 10 (rank : 169)	NC score	0.096635 (rank : 113)
Query Neighborhood Hits	77	Target Neighborhood Hits	821	Shared Neighborhood Hits	45
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

PGCA_MOUSE
θ value	θ > 10 (rank : 170)	NC score	0.102262 (rank : 109)
Query Neighborhood Hits	77	Target Neighborhood Hits	643	Shared Neighborhood Hits	40
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

PGCB_HUMAN
θ value	θ > 10 (rank : 171)	NC score	0.102840 (rank : 107)
Query Neighborhood Hits	77	Target Neighborhood Hits	478	Shared Neighborhood Hits	46
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

PGCB_MOUSE
θ value	θ > 10 (rank : 172)	NC score	0.087330 (rank : 120)
Query Neighborhood Hits	77	Target Neighborhood Hits	459	Shared Neighborhood Hits	47
SwissProt Accessions	Q61361	Gene names	Bcan
Domain Architecture
Description	Brevican core protein precursor.

POLS2_MOUSE
θ value	θ > 10 (rank : 173)	NC score	0.050292 (rank : 211)
Query Neighborhood Hits	77	Target Neighborhood Hits	188	Shared Neighborhood Hits	15
SwissProt Accessions	Q5K2P8	Gene names	Prss36
Domain Architecture	No domain graphic available
Description	Polyserase-2 precursor (EC 3.4.21.-) (Polyserine protease 2) (Protease serine 36).

PROC_HUMAN
θ value	θ > 10 (rank : 174)	NC score	0.071066 (rank : 134)
Query Neighborhood Hits	77	Target Neighborhood Hits	406	Shared Neighborhood Hits	27
SwissProt Accessions	P04070, Q15189, Q15190, Q16001	Gene names	PROC
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

PROC_MOUSE
θ value	θ > 10 (rank : 175)	NC score	0.075021 (rank : 132)
Query Neighborhood Hits	77	Target Neighborhood Hits	426	Shared Neighborhood Hits	29
SwissProt Accessions	P33587, O35498, Q91WN8, Q99PC6	Gene names	Proc
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

PROZ_HUMAN
θ value	θ > 10 (rank : 176)	NC score	0.074558 (rank : 133)
Query Neighborhood Hits	77	Target Neighborhood Hits	422	Shared Neighborhood Hits	31
SwissProt Accessions	P22891, Q15213	Gene names	PROZ
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

PROZ_MOUSE
θ value	θ > 10 (rank : 177)	NC score	0.077120 (rank : 131)
Query Neighborhood Hits	77	Target Neighborhood Hits	410	Shared Neighborhood Hits	31
SwissProt Accessions	Q9CQW3	Gene names	Proz
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

PRS27_HUMAN
θ value	θ > 10 (rank : 178)	NC score	0.055886 (rank : 159)
Query Neighborhood Hits	77	Target Neighborhood Hits	177	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BQR3	Gene names	PRSS27, MPN
Domain Architecture
Description	Protease serine 27 precursor (EC 3.4.21.-) (Marapsin) (Pancreasin) (Channel-activating protease 2) (CAPH2).

PRS27_MOUSE
θ value	θ > 10 (rank : 179)	NC score	0.052876 (rank : 186)
Query Neighborhood Hits	77	Target Neighborhood Hits	175	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BJR6	Gene names	Prss27, Mpn
Domain Architecture	No domain graphic available
Description	Protease serine 27 precursor (EC 3.4.21.-) (Marapsin) (Pancreasin).

PRSS8_HUMAN
θ value	θ > 10 (rank : 180)	NC score	0.056094 (rank : 158)
Query Neighborhood Hits	77	Target Neighborhood Hits	177	Shared Neighborhood Hits	14
SwissProt Accessions	Q16651, Q9UCA3	Gene names	PRSS8
Domain Architecture
Description	Prostasin precursor (EC 3.4.21.-) [Contains: Prostasin light chain; Prostasin heavy chain].

PRSS8_MOUSE
θ value	θ > 10 (rank : 181)	NC score	0.054238 (rank : 170)
Query Neighborhood Hits	77	Target Neighborhood Hits	177	Shared Neighborhood Hits	14
SwissProt Accessions	Q9ESD1	Gene names	Prss8, Cap1
Domain Architecture
Description	Prostasin precursor (EC 3.4.21.-) (Channel-activating protease 1) [Contains: Prostasin light chain; Prostasin heavy chain].

SCUB3_HUMAN
θ value	θ > 10 (rank : 182)	NC score	0.061381 (rank : 144)
Query Neighborhood Hits	77	Target Neighborhood Hits	428	Shared Neighborhood Hits	33
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SCUB3_MOUSE
θ value	θ > 10 (rank : 183)	NC score	0.059693 (rank : 146)
Query Neighborhood Hits	77	Target Neighborhood Hits	442	Shared Neighborhood Hits	32
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SFTPA_MOUSE
θ value	θ > 10 (rank : 184)	NC score	0.050300 (rank : 210)
Query Neighborhood Hits	77	Target Neighborhood Hits	169	Shared Neighborhood Hits	6
SwissProt Accessions	P35242	Gene names	Sftpa1, Sftp-1, Sftp1, Sftpa
Domain Architecture
Description	Pulmonary surfactant-associated protein A precursor (SP-A) (PSP-A) (PSAP).

ST14_HUMAN
θ value	θ > 10 (rank : 185)	NC score	0.085497 (rank : 124)
Query Neighborhood Hits	77	Target Neighborhood Hits	409	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y5Y6, Q9BS01, Q9H3S0, Q9HB36, Q9HCA3	Gene names	ST14, PRSS14, SNC19, TADG15
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Matriptase) (Membrane-type serine protease 1) (MT-SP1) (Prostamin) (Serine protease TADG-15) (Tumor-associated differentially-expressed gene 15 protein).

ST14_MOUSE
θ value	θ > 10 (rank : 186)	NC score	0.087476 (rank : 119)
Query Neighborhood Hits	77	Target Neighborhood Hits	419	Shared Neighborhood Hits	26
SwissProt Accessions	P56677	Gene names	St14, Prss14
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Epithin).

TEST_HUMAN
θ value	θ > 10 (rank : 187)	NC score	0.051295 (rank : 202)
Query Neighborhood Hits	77	Target Neighborhood Hits	172	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y6M0, Q9NS34, Q9P2V6	Gene names	PRSS21, ESP1, TEST1
Domain Architecture
Description	Testisin precursor (EC 3.4.21.-) (Eosinophil serine protease 1) (ESP- 1).

TEST_MOUSE
θ value	θ > 10 (rank : 188)	NC score	0.057555 (rank : 149)
Query Neighborhood Hits	77	Target Neighborhood Hits	174	Shared Neighborhood Hits	14
SwissProt Accessions	Q9JHJ7, Q9DA14	Gene names	Prss21
Domain Architecture
Description	Testisin precursor (EC 3.4.21.-) (Tryptase 4).

THRB_HUMAN
θ value	θ > 10 (rank : 189)	NC score	0.064102 (rank : 137)
Query Neighborhood Hits	77	Target Neighborhood Hits	196	Shared Neighborhood Hits	15
SwissProt Accessions	P00734	Gene names	F2
Domain Architecture
Description	Prothrombin precursor (EC 3.4.21.5) (Coagulation factor II) [Contains: Activation peptide fragment 1; Activation peptide fragment 2; Thrombin light chain; Thrombin heavy chain].

THRB_MOUSE
θ value	θ > 10 (rank : 190)	NC score	0.063949 (rank : 139)
Query Neighborhood Hits	77	Target Neighborhood Hits	195	Shared Neighborhood Hits	15
SwissProt Accessions	P19221	Gene names	F2, Cf2
Domain Architecture
Description	Prothrombin precursor (EC 3.4.21.5) (Coagulation factor II) [Contains: Activation peptide fragment 1; Activation peptide fragment 2; Thrombin light chain; Thrombin heavy chain].

TLL1_HUMAN
θ value	θ > 10 (rank : 191)	NC score	0.165763 (rank : 71)
Query Neighborhood Hits	77	Target Neighborhood Hits	236	Shared Neighborhood Hits	27
SwissProt Accessions	O43897, Q96AN3, Q9NQS4	Gene names	TLL1, TLL
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-).

TLL1_MOUSE
θ value	θ > 10 (rank : 192)	NC score	0.167732 (rank : 70)
Query Neighborhood Hits	77	Target Neighborhood Hits	237	Shared Neighborhood Hits	28
SwissProt Accessions	Q62381, Q3UTT9, Q8BNP5	Gene names	Tll1, Tll
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-) (mTll).

TLL2_HUMAN
θ value	θ > 10 (rank : 193)	NC score	0.165346 (rank : 72)
Query Neighborhood Hits	77	Target Neighborhood Hits	241	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y6L7, Q6PJN5, Q9UQ00	Gene names	TLL2, KIAA0932
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

TLL2_MOUSE
θ value	θ > 10 (rank : 194)	NC score	0.169635 (rank : 69)
Query Neighborhood Hits	77	Target Neighborhood Hits	240	Shared Neighborhood Hits	29
SwissProt Accessions	Q9WVM6	Gene names	Tll2
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

TM11D_HUMAN
θ value	θ > 10 (rank : 195)	NC score	0.054789 (rank : 165)
Query Neighborhood Hits	77	Target Neighborhood Hits	176	Shared Neighborhood Hits	14
SwissProt Accessions	O60235	Gene names	TMPRSS11D, HAT
Domain Architecture
Description	Transmembrane protease, serine 11D precursor (EC 3.4.21.-) (Airway trypsin-like protease) [Contains: Transmembrane protease, serine 11D non-catalytic chain; Transmembrane protease, serine 11D catalytic chain].

TM11D_MOUSE
θ value	θ > 10 (rank : 196)	NC score	0.055519 (rank : 162)
Query Neighborhood Hits	77	Target Neighborhood Hits	179	Shared Neighborhood Hits	14
SwissProt Accessions	Q8VHK8, Q7TNX3, Q8VDV1	Gene names	Tmprss11d, Mat
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 11D precursor (EC 3.4.21.-) (Airway trypsin-like protease) (AT) (Adrenal secretory serine protease) (AsP) [Contains: Transmembrane protease, serine 11D non-catalytic chain; Transmembrane protease, serine 11D catalytic chain].

TM11E_HUMAN
θ value	θ > 10 (rank : 197)	NC score	0.051722 (rank : 196)
Query Neighborhood Hits	77	Target Neighborhood Hits	181	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UL52, Q6UW31	Gene names	TMPRSS11E, DESC1
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 11E precursor (EC 3.4.21.-) (Serine protease DESC1) [Contains: Transmembrane protease, serine 11E non- catalytic chain; Transmembrane protease, serine 11E catalytic chain].

TM11E_MOUSE
θ value	θ > 10 (rank : 198)	NC score	0.053023 (rank : 183)
Query Neighborhood Hits	77	Target Neighborhood Hits	176	Shared Neighborhood Hits	14
SwissProt Accessions	Q5S248, Q8BM10	Gene names	Tmprss11e, Desc1
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 11E precursor (EC 3.4.21.-) (Serine protease DESC1) [Contains: Transmembrane protease, serine 11E non- catalytic chain; Transmembrane protease, serine 11E catalytic chain].

TMPS2_HUMAN
θ value	θ > 10 (rank : 199)	NC score	0.053552 (rank : 177)
Query Neighborhood Hits	77	Target Neighborhood Hits	252	Shared Neighborhood Hits	14
SwissProt Accessions	O15393, Q9BXX1	Gene names	TMPRSS2, PRSS10
Domain Architecture
Description	Transmembrane protease, serine 2 precursor (EC 3.4.21.-) [Contains: Transmembrane protease, serine 2 non-catalytic chain; Transmembrane protease, serine 2 catalytic chain].

TMPS2_MOUSE
θ value	θ > 10 (rank : 200)	NC score	0.053550 (rank : 178)
Query Neighborhood Hits	77	Target Neighborhood Hits	243	Shared Neighborhood Hits	16
SwissProt Accessions	Q9JIQ8, Q9JKC4, Q9QY82	Gene names	Tmprss2
Domain Architecture
Description	Transmembrane protease, serine 2 (EC 3.4.21.-) (Epitheliasin) (Plasmic transmembrane protein X) [Contains: Transmembrane protease, serine 2 non-catalytic chain; Transmembrane protease, serine 2 catalytic chain].

TMPS3_HUMAN
θ value	θ > 10 (rank : 201)	NC score	0.050586 (rank : 207)
Query Neighborhood Hits	77	Target Neighborhood Hits	245	Shared Neighborhood Hits	15
SwissProt Accessions	P57727, Q6ZMC3	Gene names	TMPRSS3, ECHOS1, TADG12
Domain Architecture
Description	Transmembrane protease, serine 3 (EC 3.4.21.-) (Serine protease TADG- 12) (Tumor-associated differentially-expressed gene 12 protein).

TMPS3_MOUSE
θ value	θ > 10 (rank : 202)	NC score	0.051880 (rank : 195)
Query Neighborhood Hits	77	Target Neighborhood Hits	239	Shared Neighborhood Hits	16
SwissProt Accessions	Q8K1T0, Q8VDE0	Gene names	Tmprss3
Domain Architecture
Description	Transmembrane protease, serine 3 (EC 3.4.21.-).

TMPS4_HUMAN
θ value	θ > 10 (rank : 203)	NC score	0.056954 (rank : 154)
Query Neighborhood Hits	77	Target Neighborhood Hits	203	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NRS4, Q5XKQ6, Q6UX37, Q9NZA5	Gene names	TMPRSS4, TMPRSS3
Domain Architecture
Description	Transmembrane protease, serine 4 (EC 3.4.21.-) (Membrane-type serine protease 2) (MT-SP2).

TMPS4_MOUSE
θ value	θ > 10 (rank : 204)	NC score	0.057131 (rank : 151)
Query Neighborhood Hits	77	Target Neighborhood Hits	210	Shared Neighborhood Hits	14
SwissProt Accessions	Q8VCA5	Gene names	Tmprss4, Cap2
Domain Architecture
Description	Transmembrane protease, serine 4 (EC 3.4.21.-) (Channel-activating protease 2) (mCAP2).

TMPS5_HUMAN
θ value	θ > 10 (rank : 205)	NC score	0.051961 (rank : 194)
Query Neighborhood Hits	77	Target Neighborhood Hits	181	Shared Neighborhood Hits	14
SwissProt Accessions	Q9H3S3	Gene names	TMPRSS5
Domain Architecture
Description	Transmembrane protease, serine 5 (EC 3.4.21.-) (Spinesin).

TMPS5_MOUSE
θ value	θ > 10 (rank : 206)	NC score	0.050457 (rank : 209)
Query Neighborhood Hits	77	Target Neighborhood Hits	185	Shared Neighborhood Hits	14
SwissProt Accessions	Q9ER04, Q9ER02, Q9ER03	Gene names	Tmprss5
Domain Architecture
Description	Transmembrane protease, serine 5 (EC 3.4.21.-) (Spinesin).

TMPS6_HUMAN
θ value	θ > 10 (rank : 207)	NC score	0.063309 (rank : 141)
Query Neighborhood Hits	77	Target Neighborhood Hits	338	Shared Neighborhood Hits	23
SwissProt Accessions	Q8IU80, Q5TI06, Q6UXD8, Q8IUE2, Q8IXV8	Gene names	TMPRSS6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

TMPS6_MOUSE
θ value	θ > 10 (rank : 208)	NC score	0.062436 (rank : 142)
Query Neighborhood Hits	77	Target Neighborhood Hits	341	Shared Neighborhood Hits	20
SwissProt Accessions	Q9DBI0, Q6PF94	Gene names	Tmprss6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

TMPS7_HUMAN
θ value	θ > 10 (rank : 209)	NC score	0.060340 (rank : 145)
Query Neighborhood Hits	77	Target Neighborhood Hits	275	Shared Neighborhood Hits	20
SwissProt Accessions	Q7RTY8	Gene names	TMPRSS7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

TMPS7_MOUSE
θ value	θ > 10 (rank : 210)	NC score	0.061925 (rank : 143)
Query Neighborhood Hits	77	Target Neighborhood Hits	275	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BIK6	Gene names	Tmprss7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

TMPS9_HUMAN
θ value	θ > 10 (rank : 211)	NC score	0.052471 (rank : 189)
Query Neighborhood Hits	77	Target Neighborhood Hits	276	Shared Neighborhood Hits	17
SwissProt Accessions	Q7Z410, Q6ZND6, Q7Z411	Gene names	TMPRSS9
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 9 (EC 3.4.21.-) (Polyserase-1) (Polyserase-I) (Polyserine protease 1) [Contains: Serase-1; Serase-2; Serase-3].

TMPS9_MOUSE
θ value	θ > 10 (rank : 212)	NC score	0.053074 (rank : 182)
Query Neighborhood Hits	77	Target Neighborhood Hits	296	Shared Neighborhood Hits	17
SwissProt Accessions	P69525	Gene names	Tmprss9
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 9 (EC 3.4.21.-) (Polyserase-1) (Polyserine protease 1) (Polyserase-I) [Contains: Serase-1; Serase-2; Serase-3].

TMPSD_HUMAN
θ value	θ > 10 (rank : 213)	NC score	0.053788 (rank : 175)
Query Neighborhood Hits	77	Target Neighborhood Hits	333	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BYE2, Q86YM4, Q96JY8, Q9BYE1	Gene names	TMPRSS13, MSP, TMPRSS11
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).

TMPSD_MOUSE
θ value	θ > 10 (rank : 214)	NC score	0.054796 (rank : 164)
Query Neighborhood Hits	77	Target Neighborhood Hits	334	Shared Neighborhood Hits	14
SwissProt Accessions	Q5U405, Q8CFE0, Q91VQ8	Gene names	Tmprss13, Msp
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).

TMSP8_MOUSE
θ value	θ > 10 (rank : 215)	NC score	0.057000 (rank : 153)
Query Neighborhood Hits	77	Target Neighborhood Hits	176	Shared Neighborhood Hits	14
SwissProt Accessions	Q9QYZ9, Q91XC4	Gene names	Tmprss8, Disp
Domain Architecture
Description	Transmembrane serine protease 8 precursor (EC 3.4.21.-) (Distal intestinal serine protease).

TPA_HUMAN
θ value	θ > 10 (rank : 216)	NC score	0.056097 (rank : 157)
Query Neighborhood Hits	77	Target Neighborhood Hits	324	Shared Neighborhood Hits	19
SwissProt Accessions	P00750, Q15103, Q7Z7N2, Q86YK8, Q9BU99	Gene names	PLAT
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) (Alteplase) (Reteplase) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

TPA_MOUSE
θ value	θ > 10 (rank : 217)	NC score	0.054043 (rank : 172)
Query Neighborhood Hits	77	Target Neighborhood Hits	335	Shared Neighborhood Hits	21
SwissProt Accessions	P11214, Q91VP2	Gene names	Plat
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

TRYB1_HUMAN
θ value	θ > 10 (rank : 218)	NC score	0.050670 (rank : 205)
Query Neighborhood Hits	77	Target Neighborhood Hits	175	Shared Neighborhood Hits	14
SwissProt Accessions	Q15661, Q15663, Q9H2Y4	Gene names	TPSAB1, TPSB1
Domain Architecture
Description	Tryptase beta-1 precursor (EC 3.4.21.59) (Tryptase-1) (Tryptase I).

TRYB1_MOUSE
θ value	θ > 10 (rank : 219)	NC score	0.050211 (rank : 212)
Query Neighborhood Hits	77	Target Neighborhood Hits	175	Shared Neighborhood Hits	14
SwissProt Accessions	Q02844	Gene names	Tpsab1, Mcpt7
Domain Architecture
Description	Tryptase precursor (EC 3.4.21.59) (Mast cell protease 7) (MMCP-7) (Tryptase alpha/beta-1).

TRYB2_HUMAN
θ value	θ > 10 (rank : 220)	NC score	0.050670 (rank : 206)
Query Neighborhood Hits	77	Target Neighborhood Hits	175	Shared Neighborhood Hits	14
SwissProt Accessions	P20231, O95827, Q15664, Q9UQI6, Q9UQI7	Gene names	TPSB2, TPS2
Domain Architecture
Description	Tryptase beta-2 precursor (EC 3.4.21.59) (Tryptase-2) (Tryptase II).

TRYG1_HUMAN
θ value	θ > 10 (rank : 221)	NC score	0.054137 (rank : 171)
Query Neighborhood Hits	77	Target Neighborhood Hits	179	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NRR2, Q96RZ8, Q9C015, Q9NRQ8, Q9UBB2	Gene names	TPSG1, TMT
Domain Architecture
Description	Tryptase gamma precursor (EC 3.4.21.-) (Transmembrane tryptase) [Contains: Tryptase gamma light chain; Tryptase gamma heavy chain].

TRYG1_MOUSE
θ value	θ > 10 (rank : 222)	NC score	0.052094 (rank : 191)
Query Neighborhood Hits	77	Target Neighborhood Hits	181	Shared Neighborhood Hits	14
SwissProt Accessions	Q9QUL7	Gene names	Tpsg1, Tmt
Domain Architecture
Description	Tryptase gamma precursor (EC 3.4.21.-) (Transmembrane tryptase) [Contains: Tryptase gamma light chain; Tryptase gamma heavy chain].

TSG6_HUMAN
θ value	θ > 10 (rank : 223)	NC score	0.125836 (rank : 87)
Query Neighborhood Hits	77	Target Neighborhood Hits	91	Shared Neighborhood Hits	16
SwissProt Accessions	P98066, Q8WWI9	Gene names	TNFAIP6, TSG6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein) (Hyaluronate-binding protein).

TSG6_MOUSE
θ value	θ > 10 (rank : 224)	NC score	0.127209 (rank : 85)
Query Neighborhood Hits	77	Target Neighborhood Hits	91	Shared Neighborhood Hits	16
SwissProt Accessions	O08859	Gene names	Tnfaip6, Tnfip6, Tsg6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein).

TSP50_HUMAN
θ value	θ > 10 (rank : 225)	NC score	0.054854 (rank : 163)
Query Neighborhood Hits	77	Target Neighborhood Hits	178	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UI38	Gene names	TSP50
Domain Architecture
Description	Testis-specific protease-like protein 50 precursor.

Hits sorted by NC score

C4BB_HUMAN
NC score	0.999962 (rank : 1)	θ value	1.12714e-143 (rank : 1)
Query Neighborhood Hits	77	Target Neighborhood Hits	77	Shared Neighborhood Hits	77
SwissProt Accessions	P20851	Gene names	C4BPB
Domain Architecture
Description	C4b-binding protein beta chain precursor.

CR2_MOUSE
NC score	0.879174 (rank : 2)	θ value	2.97466e-19 (rank : 6)
Query Neighborhood Hits	77	Target Neighborhood Hits	101	Shared Neighborhood Hits	68
SwissProt Accessions	P19070	Gene names	Cr2
Domain Architecture
Description	Complement receptor type 2 precursor (Cr2) (Complement C3d receptor) (CD21 antigen).

CR2_HUMAN
NC score	0.875979 (rank : 3)	θ value	7.32683e-18 (rank : 8)
Query Neighborhood Hits	77	Target Neighborhood Hits	89	Shared Neighborhood Hits	69
SwissProt Accessions	P20023, Q13866, Q14212	Gene names	CR2, C3DR
Domain Architecture
Description	Complement receptor type 2 precursor (Cr2) (Complement C3d receptor) (Epstein-Barr virus receptor) (EBV receptor) (CD21 antigen).

C4BP_MOUSE
NC score	0.874858 (rank : 4)	θ value	1.2105e-12 (rank : 17)
Query Neighborhood Hits	77	Target Neighborhood Hits	91	Shared Neighborhood Hits	67
SwissProt Accessions	P08607	Gene names	C4bpa, C4bp
Domain Architecture
Description	C4b-binding protein precursor (C4bp).

C4BP_HUMAN
NC score	0.864776 (rank : 5)	θ value	2.69671e-12 (rank : 18)
Query Neighborhood Hits	77	Target Neighborhood Hits	92	Shared Neighborhood Hits	66
SwissProt Accessions	P04003	Gene names	C4BPA, C4BP
Domain Architecture
Description	C4b-binding protein alpha chain precursor (C4bp) (Proline-rich protein) (PRP).

CR1_HUMAN
NC score	0.860115 (rank : 6)	θ value	3.76295e-14 (rank : 15)
Query Neighborhood Hits	77	Target Neighborhood Hits	108	Shared Neighborhood Hits	67
SwissProt Accessions	P17927, Q16745, Q9UQV2	Gene names	CR1, C3BR
Domain Architecture
Description	Complement receptor type 1 precursor (C3b/C4b receptor) (CD35 antigen).

APOH_HUMAN
NC score	0.856274 (rank : 7)	θ value	3.29651e-10 (rank : 25)
Query Neighborhood Hits	77	Target Neighborhood Hits	75	Shared Neighborhood Hits	66
SwissProt Accessions	P02749, Q9UCN7	Gene names	APOH, B2G1
Domain Architecture
Description	Beta-2-glycoprotein 1 precursor (Beta-2-glycoprotein I) (Apolipoprotein H) (Apo-H) (B2GPI) (Beta(2)GPI) (Activated protein C- binding protein) (APC inhibitor) (Anticardiolipin cofactor).

ZP3R_MOUSE
NC score	0.854100 (rank : 8)	θ value	3.89403e-11 (rank : 21)
Query Neighborhood Hits	77	Target Neighborhood Hits	81	Shared Neighborhood Hits	65
SwissProt Accessions	Q60736	Gene names	Zp3r, Sp56
Domain Architecture
Description	Zona pellucida sperm-binding protein 3 receptor precursor (Sperm fertilization protein 56) (sp56).

CRRY_MOUSE
NC score	0.853214 (rank : 9)	θ value	8.67504e-11 (rank : 22)
Query Neighborhood Hits	77	Target Neighborhood Hits	84	Shared Neighborhood Hits	68
SwissProt Accessions	Q64735, Q3TV30, Q58E68, Q61447, Q61449, Q8CF59, Q8K328	Gene names	Crry, Cry
Domain Architecture	No domain graphic available
Description	Complement regulatory protein Crry precursor (Protein p65).

MCP_HUMAN
NC score	0.851146 (rank : 10)	θ value	1.63604e-09 (rank : 30)
Query Neighborhood Hits	77	Target Neighborhood Hits	82	Shared Neighborhood Hits	66
SwissProt Accessions	P15529, Q15429, Q53GV9, Q5HY94, Q5VWS6, Q5VWS7, Q5VWS8, Q5VWS9, Q5VWT0, Q5VWT1, Q5VWT2, Q6N0A1, Q7Z3R5, Q9NNW2, Q9NNW3, Q9NNW4	Gene names	CD46, MCP
Domain Architecture
Description	Membrane cofactor protein precursor (Trophoblast leukocyte common antigen) (TLX) (CD46 antigen).

APOH_MOUSE
NC score	0.850150 (rank : 11)	θ value	1.47974e-10 (rank : 23)
Query Neighborhood Hits	77	Target Neighborhood Hits	74	Shared Neighborhood Hits	63
SwissProt Accessions	Q01339	Gene names	Apoh, B2gp1
Domain Architecture
Description	Beta-2-glycoprotein 1 precursor (Beta-2-glycoprotein I) (Apolipoprotein H) (Apo-H) (B2GPI) (Beta(2)GPI) (Activated protein C- binding protein) (APC inhibitor).

DAF_HUMAN
NC score	0.846104 (rank : 12)	θ value	2.28291e-11 (rank : 20)
Query Neighborhood Hits	77	Target Neighborhood Hits	97	Shared Neighborhood Hits	66
SwissProt Accessions	P08174, P09679, P78361	Gene names	CD55, CR, DAF
Domain Architecture
Description	Complement decay-accelerating factor precursor (CD55 antigen).

MCP_MOUSE
NC score	0.839887 (rank : 13)	θ value	5.62301e-10 (rank : 26)
Query Neighborhood Hits	77	Target Neighborhood Hits	79	Shared Neighborhood Hits	64
SwissProt Accessions	O88174, Q9R0R9	Gene names	Cd46, Mcp
Domain Architecture	No domain graphic available
Description	Membrane cofactor protein precursor (CD46 antigen).

F13B_MOUSE
NC score	0.820227 (rank : 14)	θ value	1.74796e-11 (rank : 19)
Query Neighborhood Hits	77	Target Neighborhood Hits	93	Shared Neighborhood Hits	62
SwissProt Accessions	Q07968	Gene names	F13b, Cf13b
Domain Architecture
Description	Coagulation factor XIII B chain precursor (Protein-glutamine gamma- glutamyltransferase B chain) (Transglutaminase B chain).

DAF2_MOUSE
NC score	0.807294 (rank : 15)	θ value	2.61198e-07 (rank : 35)
Query Neighborhood Hits	77	Target Neighborhood Hits	114	Shared Neighborhood Hits	67
SwissProt Accessions	Q61476	Gene names	Cd55b, Daf2
Domain Architecture
Description	Complement decay-accelerating factor transmembrane isoform precursor (DAF-TM) (CD55 antigen).

DAF1_MOUSE
NC score	0.806931 (rank : 16)	θ value	2.79066e-09 (rank : 31)
Query Neighborhood Hits	77	Target Neighborhood Hits	204	Shared Neighborhood Hits	68
SwissProt Accessions	Q61475, P97732, Q61397	Gene names	Cd55a, Daf1
Domain Architecture
Description	Complement decay-accelerating factor, GPI-anchored precursor (DAF-GPI) (CD55 antigen).

F13B_HUMAN
NC score	0.802750 (rank : 17)	θ value	2.52405e-10 (rank : 24)
Query Neighborhood Hits	77	Target Neighborhood Hits	84	Shared Neighborhood Hits	62
SwissProt Accessions	P05160	Gene names	F13B
Domain Architecture
Description	Coagulation factor XIII B chain precursor (Protein-glutamine gamma- glutamyltransferase B chain) (Transglutaminase B chain) (Fibrin- stabilizing factor B subunit).

CFAH_MOUSE
NC score	0.801892 (rank : 18)	θ value	9.59137e-10 (rank : 29)
Query Neighborhood Hits	77	Target Neighborhood Hits	112	Shared Neighborhood Hits	68
SwissProt Accessions	P06909	Gene names	Cfh, Hf1
Domain Architecture
Description	Complement factor H precursor (Protein beta-1-H).

CFAH_HUMAN
NC score	0.797106 (rank : 19)	θ value	9.59137e-10 (rank : 28)
Query Neighborhood Hits	77	Target Neighborhood Hits	101	Shared Neighborhood Hits	66
SwissProt Accessions	P08603, P78435, Q14570, Q38G77, Q5TFM3, Q8N708, Q9NU86	Gene names	CFH, HF, HF1
Domain Architecture
Description	Complement factor H precursor (H factor 1).

FHR5_HUMAN
NC score	0.750485 (rank : 20)	θ value	7.34386e-10 (rank : 27)
Query Neighborhood Hits	77	Target Neighborhood Hits	77	Shared Neighborhood Hits	61
SwissProt Accessions	Q9BXR6	Gene names	CFHL5, FHR5
Domain Architecture
Description	Complement factor H-related protein 5 precursor (FHR-5).

LYAM3_HUMAN
NC score	0.747704 (rank : 21)	θ value	5.8054e-15 (rank : 14)
Query Neighborhood Hits	77	Target Neighborhood Hits	378	Shared Neighborhood Hits	75
SwissProt Accessions	P16109, Q8IVD1	Gene names	SELP, GMRP
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

LYAM3_MOUSE
NC score	0.742275 (rank : 22)	θ value	6.85773e-16 (rank : 13)
Query Neighborhood Hits	77	Target Neighborhood Hits	390	Shared Neighborhood Hits	76
SwissProt Accessions	Q01102	Gene names	Selp, Grmp
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

CSMD3_HUMAN
NC score	0.741707 (rank : 23)	θ value	4.9032e-22 (rank : 4)
Query Neighborhood Hits	77	Target Neighborhood Hits	199	Shared Neighborhood Hits	69
SwissProt Accessions	Q7Z407, Q96PZ3	Gene names	CSMD3, KIAA1894
Domain Architecture
Description	CUB and sushi domain-containing protein 3 precursor (CUB and sushi multiple domains protein 3).

CSMD1_HUMAN
NC score	0.739925 (rank : 24)	θ value	5.97985e-28 (rank : 2)
Query Neighborhood Hits	77	Target Neighborhood Hits	176	Shared Neighborhood Hits	69
SwissProt Accessions	Q96PZ7, Q96QU9, Q96RM4	Gene names	CSMD1, KIAA1890
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

CSMD1_MOUSE
NC score	0.733539 (rank : 25)	θ value	4.9032e-22 (rank : 3)
Query Neighborhood Hits	77	Target Neighborhood Hits	193	Shared Neighborhood Hits	72
SwissProt Accessions	Q923L3, Q8BUV1, Q8BYQ3	Gene names	Csmd1
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

LYAM2_HUMAN
NC score	0.727711 (rank : 26)	θ value	6.20254e-17 (rank : 11)
Query Neighborhood Hits	77	Target Neighborhood Hits	394	Shared Neighborhood Hits	75
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

LYAM2_MOUSE
NC score	0.722385 (rank : 27)	θ value	1.47631e-18 (rank : 7)
Query Neighborhood Hits	77	Target Neighborhood Hits	420	Shared Neighborhood Hits	76
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

CSMD2_HUMAN
NC score	0.722285 (rank : 28)	θ value	7.0802e-21 (rank : 5)
Query Neighborhood Hits	77	Target Neighborhood Hits	188	Shared Neighborhood Hits	68
SwissProt Accessions	Q7Z408, Q5VT59, Q8N963, Q96Q03, Q9H4V7, Q9H4V8, Q9H4V9, Q9H4W0, Q9H4W1, Q9H4W2, Q9H4W3, Q9H4W4, Q9HCY5, Q9HCY6, Q9HCY7	Gene names	CSMD2, KIAA1884
Domain Architecture
Description	CUB and sushi domain-containing protein 2 (CUB and sushi multiple domains protein 2).

SEZ6L_HUMAN
NC score	0.718077 (rank : 29)	θ value	4.02038e-16 (rank : 12)
Query Neighborhood Hits	77	Target Neighborhood Hits	289	Shared Neighborhood Hits	68
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.

SRPX_MOUSE
NC score	0.716223 (rank : 30)	θ value	3.77169e-06 (rank : 39)
Query Neighborhood Hits	77	Target Neighborhood Hits	75	Shared Neighborhood Hits	57
SwissProt Accessions	Q9R0M3, Q9R0M2	Gene names	Srpx
Domain Architecture	No domain graphic available
Description	Sushi-repeat-containing protein SRPX precursor (DRS protein).

SUSD4_MOUSE
NC score	0.708080 (rank : 31)	θ value	9.29e-05 (rank : 47)
Query Neighborhood Hits	77	Target Neighborhood Hits	122	Shared Neighborhood Hits	61
SwissProt Accessions	Q8BH32, Q8VC43	Gene names	Susd4
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 4 precursor.

SRPX_HUMAN
NC score	0.707083 (rank : 32)	θ value	3.77169e-06 (rank : 38)
Query Neighborhood Hits	77	Target Neighborhood Hits	69	Shared Neighborhood Hits	55
SwissProt Accessions	P78539, Q99652, Q99913	Gene names	SRPX, ETX1
Domain Architecture
Description	Sushi repeat-containing protein SRPX precursor.

SUSD4_HUMAN
NC score	0.704558 (rank : 33)	θ value	0.000461057 (rank : 50)
Query Neighborhood Hits	77	Target Neighborhood Hits	88	Shared Neighborhood Hits	61
SwissProt Accessions	Q5VX71, Q6UX62, Q9BSR0, Q9NWG0	Gene names	SUSD4
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 4 precursor.

FHR1_HUMAN
NC score	0.700078 (rank : 34)	θ value	1.53129e-07 (rank : 33)
Query Neighborhood Hits	77	Target Neighborhood Hits	80	Shared Neighborhood Hits	60
SwissProt Accessions	Q03591, Q9UJ17	Gene names	CFHL1, CFHL, FHR1, HFL1
Domain Architecture
Description	Complement factor H-related protein 1 precursor (FHR-1) (H factor-like protein 1) (H-factor-like 1) (H36).

FHR3_HUMAN
NC score	0.673501 (rank : 35)	θ value	9.92553e-07 (rank : 36)
Query Neighborhood Hits	77	Target Neighborhood Hits	74	Shared Neighborhood Hits	59
SwissProt Accessions	Q02985, Q9UJ16	Gene names	CFHL3, FHR3
Domain Architecture
Description	Complement factor H-related protein 3 precursor (FHR-3) (H factor-like protein 3) (DOWN16).

FHR2_HUMAN
NC score	0.653925 (rank : 36)	θ value	1.53129e-07 (rank : 34)
Query Neighborhood Hits	77	Target Neighborhood Hits	63	Shared Neighborhood Hits	56
SwissProt Accessions	P36980, Q14310	Gene names	CFHL2, FHR2, HFL3
Domain Architecture
Description	Complement factor H-related protein 2 precursor (FHR-2) (H factor-like protein 2) (H factor-like 3) (DDESK59).

FHR4_HUMAN
NC score	0.653837 (rank : 37)	θ value	0.00228821 (rank : 53)
Query Neighborhood Hits	77	Target Neighborhood Hits	75	Shared Neighborhood Hits	59
SwissProt Accessions	Q92496, Q9UJY6	Gene names	CFHL4, FHR4
Domain Architecture
Description	Complement factor H-related protein 4 precursor (FHR-4).

LYAM1_MOUSE
NC score	0.559595 (rank : 38)	θ value	1.80886e-08 (rank : 32)
Query Neighborhood Hits	77	Target Neighborhood Hits	332	Shared Neighborhood Hits	65
SwissProt Accessions	P18337	Gene names	Sell, Lnhr, Ly-22
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Lymphocyte antigen 22) (Ly-22) (Lymphocyte surface MEL-14 antigen) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

LYAM1_HUMAN
NC score	0.556038 (rank : 39)	θ value	5.44631e-05 (rank : 44)
Query Neighborhood Hits	77	Target Neighborhood Hits	315	Shared Neighborhood Hits	63
SwissProt Accessions	P14151, P15023	Gene names	SELL, LNHR, LYAM1
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Leukocyte surface antigen Leu-8) (TQ1) (gp90-MEL) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

PAPPA_MOUSE
NC score	0.540518 (rank : 40)	θ value	0.000786445 (rank : 52)
Query Neighborhood Hits	77	Target Neighborhood Hits	153	Shared Neighborhood Hits	56
SwissProt Accessions	Q8R4K8, Q80VW3, Q80YY1, Q8K423, Q8R4K7, Q9ES06, Q9JK57	Gene names	Pappa
Domain Architecture	No domain graphic available
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

PAPPA_HUMAN
NC score	0.540347 (rank : 41)	θ value	0.0193708 (rank : 57)
Query Neighborhood Hits	77	Target Neighborhood Hits	161	Shared Neighborhood Hits	57
SwissProt Accessions	Q13219, Q08371, Q68G52, Q9UDK7	Gene names	PAPPA
Domain Architecture
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

CFAB_MOUSE
NC score	0.536549 (rank : 42)	θ value	4.74913e-17 (rank : 10)
Query Neighborhood Hits	77	Target Neighborhood Hits	262	Shared Neighborhood Hits	64
SwissProt Accessions	P04186	Gene names	Cfb, Bf, H2-Bf
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

CFAB_HUMAN
NC score	0.535666 (rank : 43)	θ value	2.13179e-17 (rank : 9)
Query Neighborhood Hits	77	Target Neighborhood Hits	251	Shared Neighborhood Hits	64
SwissProt Accessions	P00751, O15006, Q29944, Q96HX6, Q9BTF5, Q9BX92	Gene names	CFB, BF
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) (Properdin factor B) (Glycine-rich beta glycoprotein) (GBG) (PBF2) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

CO2_HUMAN
NC score	0.526859 (rank : 44)	θ value	7.09661e-13 (rank : 16)
Query Neighborhood Hits	77	Target Neighborhood Hits	258	Shared Neighborhood Hits	60
SwissProt Accessions	P06681, O19694, Q13904	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

SUSD2_HUMAN
NC score	0.479670 (rank : 45)	θ value	2.44474e-05 (rank : 43)
Query Neighborhood Hits	77	Target Neighborhood Hits	99	Shared Neighborhood Hits	63
SwissProt Accessions	Q9UGT4, Q9H5Y6	Gene names	SUSD2
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 2 precursor.

PAP2_HUMAN
NC score	0.472784 (rank : 46)	θ value	5.44631e-05 (rank : 45)
Query Neighborhood Hits	77	Target Neighborhood Hits	106	Shared Neighborhood Hits	51
SwissProt Accessions	Q9BXP8, Q96PH7, Q96PH8, Q9H4C9	Gene names	PAPPA2
Domain Architecture	No domain graphic available
Description	Pappalysin-2 precursor (EC 3.4.24.-) (Pregnancy-associated plasma protein-A2) (PAPP-A2) (Pregnancy-associated plasma protein-E1) (PAPP- E).

SUSD2_MOUSE
NC score	0.459025 (rank : 47)	θ value	0.21417 (rank : 64)
Query Neighborhood Hits	77	Target Neighborhood Hits	104	Shared Neighborhood Hits	61
SwissProt Accessions	Q9DBX3, Q8BY19, Q8BYN0, Q8BYZ3, Q8BYZ9, Q8BZQ4, Q8C179	Gene names	Susd2
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 2 precursor.

CO2_MOUSE
NC score	0.453358 (rank : 48)	θ value	2.21117e-06 (rank : 37)
Query Neighborhood Hits	77	Target Neighborhood Hits	250	Shared Neighborhood Hits	61
SwissProt Accessions	P21180	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

CO7_HUMAN
NC score	0.384559 (rank : 49)	θ value	0.000158464 (rank : 48)
Query Neighborhood Hits	77	Target Neighborhood Hits	278	Shared Neighborhood Hits	50
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

SUSD3_MOUSE
NC score	0.366263 (rank : 50)	θ value	0.47712 (rank : 66)
Query Neighborhood Hits	77	Target Neighborhood Hits	39	Shared Neighborhood Hits	36
SwissProt Accessions	Q9D176, Q80XL5, Q9CYV1, Q9DA86	Gene names	Susd3
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 3.

CO6_HUMAN
NC score	0.335368 (rank : 51)	θ value	0.000461057 (rank : 49)
Query Neighborhood Hits	77	Target Neighborhood Hits	331	Shared Neighborhood Hits	62
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

GABR1_HUMAN
NC score	0.324147 (rank : 52)	θ value	0.0148317 (rank : 55)
Query Neighborhood Hits	77	Target Neighborhood Hits	142	Shared Neighborhood Hits	48
SwissProt Accessions	Q9UBS5, O95375, O95468, O95975, O96022, Q86W60, Q9UQQ0	Gene names	GABBR1, GPRC3A
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 1 precursor (GABA-B receptor 1) (GABA-B-R1) (Gb1).

GABR1_MOUSE
NC score	0.322406 (rank : 53)	θ value	0.0148317 (rank : 56)
Query Neighborhood Hits	77	Target Neighborhood Hits	139	Shared Neighborhood Hits	48
SwissProt Accessions	Q9WV18, Q9WU48, Q9WV15, Q9WV16, Q9WV17	Gene names	Gabbr1
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 1 precursor (GABA-B receptor 1) (GABA-B-R1) (Gb1).

SUSD1_HUMAN
NC score	0.277699 (rank : 54)	θ value	1.06291 (rank : 67)
Query Neighborhood Hits	77	Target Neighborhood Hits	285	Shared Neighborhood Hits	58
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

MASP2_MOUSE
NC score	0.263019 (rank : 55)	θ value	1.87187e-05 (rank : 41)
Query Neighborhood Hits	77	Target Neighborhood Hits	382	Shared Neighborhood Hits	64
SwissProt Accessions	Q91WP0, Q9QXA4, Q9QXD2, Q9QXD5, Q9Z338	Gene names	Masp2
Domain Architecture	No domain graphic available
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

MASP2_HUMAN
NC score	0.249968 (rank : 56)	θ value	4.92598e-06 (rank : 40)
Query Neighborhood Hits	77	Target Neighborhood Hits	364	Shared Neighborhood Hits	62
SwissProt Accessions	O00187, O75754, Q5TEQ5, Q5TER0, Q96QG4, Q9BZH0, Q9H498, Q9H499, Q9UBP3, Q9ULC7, Q9UMV3, Q9Y270	Gene names	MASP2
Domain Architecture
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

SUSD3_HUMAN
NC score	0.242700 (rank : 57)	θ value	0.365318 (rank : 65)
Query Neighborhood Hits	77	Target Neighborhood Hits	32	Shared Neighborhood Hits	28
SwissProt Accessions	Q96L08, Q49AA6, Q6UXV7	Gene names	SUSD3, UNQ9387/PRO34275
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 3.

C1S_HUMAN
NC score	0.241980 (rank : 58)	θ value	0.0563607 (rank : 61)
Query Neighborhood Hits	77	Target Neighborhood Hits	359	Shared Neighborhood Hits	60
SwissProt Accessions	P09871, Q9UCU7, Q9UCU8, Q9UCU9, Q9UCV0, Q9UCV1, Q9UCV2, Q9UCV3, Q9UCV4, Q9UCV5, Q9UM14	Gene names	C1S
Domain Architecture
Description	Complement C1s subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s subcomponent heavy chain; Complement C1s subcomponent light chain].

MASP1_HUMAN
NC score	0.231104 (rank : 59)	θ value	2.44474e-05 (rank : 42)
Query Neighborhood Hits	77	Target Neighborhood Hits	369	Shared Neighborhood Hits	63
SwissProt Accessions	P48740, O95570, Q9UF09	Gene names	MASP1, CRARF, CRARF1, PRSS5
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) (Mannose-binding protein- associated serine protease) (MASP-1) [Contains: Complement-activating component of Ra-reactive factor heavy chain; Complement-activating component of Ra-reactive factor light chain].

MASP1_MOUSE
NC score	0.225083 (rank : 60)	θ value	0.000602161 (rank : 51)
Query Neighborhood Hits	77	Target Neighborhood Hits	364	Shared Neighborhood Hits	59
SwissProt Accessions	P98064	Gene names	Masp1, Crarf
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) [Contains: Complement- activating component of Ra-reactive factor heavy chain; Complement- activating component of Ra-reactive factor light chain].

PERT_MOUSE
NC score	0.224090 (rank : 61)	θ value	7.1131e-05 (rank : 46)
Query Neighborhood Hits	77	Target Neighborhood Hits	221	Shared Neighborhood Hits	58
SwissProt Accessions	P35419, Q8C8B1	Gene names	Tpo
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

K0247_HUMAN
NC score	0.223899 (rank : 62)	θ value	θ > 10 (rank : 138)
Query Neighborhood Hits	77	Target Neighborhood Hits	42	Shared Neighborhood Hits	29
SwissProt Accessions	Q92537	Gene names	KIAA0247
Domain Architecture	No domain graphic available
Description	Protein KIAA0247 precursor.

CS1B_MOUSE
NC score	0.219060 (rank : 63)	θ value	1.38821 (rank : 68)
Query Neighborhood Hits	77	Target Neighborhood Hits	361	Shared Neighborhood Hits	60
SwissProt Accessions	Q8CFG8	Gene names	C1sb, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-B subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-B subcomponent heavy chain; Complement C1s-B subcomponent light chain].

CS1A_MOUSE
NC score	0.217543 (rank : 64)	θ value	4.03905 (rank : 70)
Query Neighborhood Hits	77	Target Neighborhood Hits	360	Shared Neighborhood Hits	60
SwissProt Accessions	Q8CG14, Q8BJC4, Q8CH28, Q8VBY4	Gene names	C1sa, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-A subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-A subcomponent heavy chain; Complement C1s-A subcomponent light chain].

C1RA_MOUSE
NC score	0.216233 (rank : 65)	θ value	0.21417 (rank : 63)
Query Neighborhood Hits	77	Target Neighborhood Hits	379	Shared Neighborhood Hits	55
SwissProt Accessions	Q8CG16, Q99KI6, Q9ET60	Gene names	C1ra, C1r
Domain Architecture
Description	Complement C1r-A subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-A subcomponent) [Contains: Complement C1r-A subcomponent heavy chain; Complement C1r-A subcomponent light chain].

C1RB_MOUSE
NC score	0.214731 (rank : 66)	θ value	0.0431538 (rank : 58)
Query Neighborhood Hits	77	Target Neighborhood Hits	380	Shared Neighborhood Hits	54
SwissProt Accessions	Q8CFG9	Gene names	C1rb, C1r
Domain Architecture	No domain graphic available
Description	Complement C1r-B subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-B subcomponent) [Contains: Complement C1r-B subcomponent heavy chain; Complement C1r-B subcomponent light chain].

C1R_HUMAN
NC score	0.210399 (rank : 67)	θ value	0.00298849 (rank : 54)
Query Neighborhood Hits	77	Target Neighborhood Hits	364	Shared Neighborhood Hits	54
SwissProt Accessions	P00736, Q8J012	Gene names	C1R
Domain Architecture
Description	Complement C1r subcomponent precursor (EC 3.4.21.41) (Complement component 1, r subcomponent) [Contains: Complement C1r subcomponent heavy chain; Complement C1r subcomponent light chain].

PERT_HUMAN
NC score	0.200483 (rank : 68)	θ value	0.0431538 (rank : 60)
Query Neighborhood Hits	77	Target Neighborhood Hits	221	Shared Neighborhood Hits	57
SwissProt Accessions	P07202, P09934, P09935, Q8IUL0, Q8NF94, Q8NF95, Q8NF96, Q8NF97, Q8TCI9	Gene names	TPO
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

TLL2_MOUSE
NC score	0.169635 (rank : 69)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	77	Target Neighborhood Hits	240	Shared Neighborhood Hits	29
SwissProt Accessions	Q9WVM6	Gene names	Tll2
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

TLL1_MOUSE
NC score	0.167732 (rank : 70)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	77	Target Neighborhood Hits	237	Shared Neighborhood Hits	28
SwissProt Accessions	Q62381, Q3UTT9, Q8BNP5	Gene names	Tll1, Tll
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-) (mTll).

TLL1_HUMAN
NC score	0.165763 (rank : 71)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	77	Target Neighborhood Hits	236	Shared Neighborhood Hits	27
SwissProt Accessions	O43897, Q96AN3, Q9NQS4	Gene names	TLL1, TLL
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-).

TLL2_HUMAN
NC score	0.165346 (rank : 72)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	77	Target Neighborhood Hits	241	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y6L7, Q6PJN5, Q9UQ00	Gene names	TLL2, KIAA0932
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

BMP1_MOUSE
NC score	0.165318 (rank : 73)	θ value	θ > 10 (rank : 85)
Query Neighborhood Hits	77	Target Neighborhood Hits	236	Shared Neighborhood Hits	27
SwissProt Accessions	P98063	Gene names	Bmp1
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

BMP1_HUMAN
NC score	0.164919 (rank : 74)	θ value	θ > 10 (rank : 84)
Query Neighborhood Hits	77	Target Neighborhood Hits	233	Shared Neighborhood Hits	27
SwissProt Accessions	P13497, Q13292, Q13872, Q14874, Q99421, Q99422, Q99423, Q9UL38	Gene names	BMP1, PCOLC
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

PCOC1_HUMAN
NC score	0.158600 (rank : 75)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	77	Target Neighborhood Hits	146	Shared Neighborhood Hits	16
SwissProt Accessions	Q15113, O14550	Gene names	PCOLCE, PCPE1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein).

PCOC1_MOUSE
NC score	0.157349 (rank : 76)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	77	Target Neighborhood Hits	100	Shared Neighborhood Hits	16
SwissProt Accessions	Q61398, O35113	Gene names	Pcolce, Pcpe1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein) (P14).

PCOC2_HUMAN
NC score	0.147038 (rank : 77)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	77	Target Neighborhood Hits	73	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UKZ9, Q9BRH3	Gene names	PCOLCE2, PCPE2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

MFRP_MOUSE
NC score	0.144799 (rank : 78)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	77	Target Neighborhood Hits	166	Shared Neighborhood Hits	17
SwissProt Accessions	Q8K480, Q8BPP4	Gene names	Mfrp
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

PCOC2_MOUSE
NC score	0.143760 (rank : 79)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	77	Target Neighborhood Hits	73	Shared Neighborhood Hits	16
SwissProt Accessions	Q8R4W6, Q3V1K6, Q9CX06	Gene names	Pcolce2, Pcpe2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

MFRP_HUMAN
NC score	0.139059 (rank : 80)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	77	Target Neighborhood Hits	165	Shared Neighborhood Hits	17
SwissProt Accessions	Q9BY79, Q335M3, Q96DQ9	Gene names	MFRP
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

CUBN_HUMAN
NC score	0.138396 (rank : 81)	θ value	θ > 10 (rank : 107)
Query Neighborhood Hits	77	Target Neighborhood Hits	482	Shared Neighborhood Hits	35
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

CUZD1_HUMAN
NC score	0.131434 (rank : 82)	θ value	θ > 10 (rank : 109)
Query Neighborhood Hits	77	Target Neighborhood Hits	89	Shared Neighborhood Hits	16
SwissProt Accessions	Q86UP6, Q7Z660, Q7Z661, Q86SG1, Q86UP5, Q9HAR7	Gene names	CUZD1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Transmembrane protein UO-44).

PDGFD_HUMAN
NC score	0.128061 (rank : 83)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	77	Target Neighborhood Hits	74	Shared Neighborhood Hits	15
SwissProt Accessions	Q9GZP0, Q9BWV5	Gene names	PDGFD, IEGF, SCDGFB
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor D precursor (PDGF D) (Iris-expressed growth factor) (Spinal cord-derived growth factor B) (SCDGF-B).

CUBN_MOUSE
NC score	0.127644 (rank : 84)	θ value	θ > 10 (rank : 108)
Query Neighborhood Hits	77	Target Neighborhood Hits	477	Shared Neighborhood Hits	34
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

TSG6_MOUSE
NC score	0.127209 (rank : 85)	θ value	θ > 10 (rank : 224)
Query Neighborhood Hits	77	Target Neighborhood Hits	91	Shared Neighborhood Hits	16
SwissProt Accessions	O08859	Gene names	Tnfaip6, Tnfip6, Tsg6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein).

NRP2_MOUSE
NC score	0.127187 (rank : 86)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	77	Target Neighborhood Hits	113	Shared Neighborhood Hits	16
SwissProt Accessions	O35375, O35373, O35374, O35376, O35377, O35378	Gene names	Nrp2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

TSG6_HUMAN
NC score	0.125836 (rank : 87)	θ value	θ > 10 (rank : 223)
Query Neighborhood Hits	77	Target Neighborhood Hits	91	Shared Neighborhood Hits	16
SwissProt Accessions	P98066, Q8WWI9	Gene names	TNFAIP6, TSG6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein) (Hyaluronate-binding protein).

NRP2_HUMAN
NC score	0.125513 (rank : 88)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	77	Target Neighborhood Hits	120	Shared Neighborhood Hits	16
SwissProt Accessions	O60462, O14820, O14821	Gene names	NRP2, VEGF165R2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

PDGFD_MOUSE
NC score	0.122316 (rank : 89)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	77	Target Neighborhood Hits	72	Shared Neighborhood Hits	14
SwissProt Accessions	Q925I7, Q3URF6, Q8K2L3, Q9D1L8	Gene names	Pdgfd, Scdgfb
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor chain precursor (PDGF D) (Spinal cord- derived growth factor B) (SCDGF-B).

CUZD1_MOUSE
NC score	0.121131 (rank : 90)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	77	Target Neighborhood Hits	91	Shared Neighborhood Hits	16
SwissProt Accessions	P70412, Q9CTZ7	Gene names	Cuzd1, Itmap1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Integral membrane-associated protein 1).

NETO1_HUMAN
NC score	0.119599 (rank : 91)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	77	Target Neighborhood Hits	110	Shared Neighborhood Hits	18
SwissProt Accessions	Q8TDF5, Q86W85, Q8ND78, Q8TDF4	Gene names	NETO1, BTCL1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

NETO1_MOUSE
NC score	0.119474 (rank : 92)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	77	Target Neighborhood Hits	109	Shared Neighborhood Hits	18
SwissProt Accessions	Q8R4I7, Q80X39, Q8C4S3, Q8CCM2	Gene names	Neto1, Btcl1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

LRP12_MOUSE
NC score	0.119037 (rank : 93)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	77	Target Neighborhood Hits	180	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BUJ9, Q8BWM9	Gene names	Lrp12
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor.

LRP12_HUMAN
NC score	0.118827 (rank : 94)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	77	Target Neighborhood Hits	205	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y561	Gene names	LRP12, ST7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor (Suppressor of tumorigenicity protein 7).

CSPG3_MOUSE
NC score	0.118621 (rank : 95)	θ value	θ > 10 (rank : 106)
Query Neighborhood Hits	77	Target Neighborhood Hits	657	Shared Neighborhood Hits	55
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

NETO2_HUMAN
NC score	0.116709 (rank : 96)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	77	Target Neighborhood Hits	109	Shared Neighborhood Hits	18
SwissProt Accessions	Q8NC67, Q7Z381, Q8ND51, Q96SP4, Q9NVY8	Gene names	NETO2, BTCL2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

NETO2_MOUSE
NC score	0.115382 (rank : 97)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	77	Target Neighborhood Hits	113	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BNJ6, Q5VM49, Q8C4Q8	Gene names	Neto2, Btcl2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

NRP1_MOUSE
NC score	0.114502 (rank : 98)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	77	Target Neighborhood Hits	120	Shared Neighborhood Hits	16
SwissProt Accessions	P97333	Gene names	Nrp1, Nrp
Domain Architecture
Description	Neuropilin-1 precursor (A5 protein).

DMBT1_MOUSE
NC score	0.113473 (rank : 99)	θ value	θ > 10 (rank : 117)
Query Neighborhood Hits	77	Target Neighborhood Hits	134	Shared Neighborhood Hits	16
SwissProt Accessions	Q60997, Q80YC6, Q9JMJ9	Gene names	Dmbt1, Crpd
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (CRP-ductin) (Vomeroglandin).

HPT_HUMAN
NC score	0.112793 (rank : 100)	θ value	θ > 10 (rank : 135)
Query Neighborhood Hits	77	Target Neighborhood Hits	184	Shared Neighborhood Hits	32
SwissProt Accessions	P00738, P00737, Q2PP15, Q3B7J0, Q6LBY9	Gene names	HP
Domain Architecture
Description	Haptoglobin precursor [Contains: Haptoglobin alpha chain; Haptoglobin beta chain].

DCBD1_MOUSE
NC score	0.112603 (rank : 101)	θ value	θ > 10 (rank : 112)
Query Neighborhood Hits	77	Target Neighborhood Hits	89	Shared Neighborhood Hits	15
SwissProt Accessions	Q9D4J3, Q8R327, Q9D696	Gene names	Dcbld1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

NRP1_HUMAN
NC score	0.112197 (rank : 102)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	77	Target Neighborhood Hits	119	Shared Neighborhood Hits	16
SwissProt Accessions	O14786, O60461, Q96IH5	Gene names	NRP1, NRP, VEGF165R
Domain Architecture
Description	Neuropilin-1 precursor (Vascular endothelial cell growth factor 165 receptor) (CD304 antigen).

KREM1_MOUSE
NC score	0.111455 (rank : 103)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	77	Target Neighborhood Hits	92	Shared Neighborhood Hits	16
SwissProt Accessions	Q99N43	Gene names	Kremen1, Kremen
Domain Architecture
Description	Kremen protein 1 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 1) (Dickkopf receptor).

KREM2_HUMAN
NC score	0.110896 (rank : 104)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	77	Target Neighborhood Hits	93	Shared Neighborhood Hits	16
SwissProt Accessions	Q8NCW0, Q8N2J4, Q8NCW1, Q96GL8, Q9BTP9	Gene names	KREMEN2, KRM2
Domain Architecture
Description	Kremen protein 2 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 2) (Dickkopf receptor 2).

CSPG3_HUMAN
NC score	0.110222 (rank : 105)	θ value	θ > 10 (rank : 105)
Query Neighborhood Hits	77	Target Neighborhood Hits	676	Shared Neighborhood Hits	55
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

KREM1_HUMAN
NC score	0.109701 (rank : 106)	θ value	θ > 10 (rank : 142)
Query Neighborhood Hits	77	Target Neighborhood Hits	90	Shared Neighborhood Hits	16
SwissProt Accessions	Q96MU8, Q5TIB9, Q6P3X6, Q9BY70, Q9UGS5, Q9UGU1	Gene names	KREMEN1, KREMEN, KRM1
Domain Architecture
Description	Kremen protein 1 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 1) (Dickkopf receptor).

PGCB_HUMAN
NC score	0.102840 (rank : 107)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	77	Target Neighborhood Hits	478	Shared Neighborhood Hits	46
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

CSPG2_MOUSE
NC score	0.102323 (rank : 108)	θ value	θ > 10 (rank : 104)
Query Neighborhood Hits	77	Target Neighborhood Hits	711	Shared Neighborhood Hits	49
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

PGCA_MOUSE
NC score	0.102262 (rank : 109)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	77	Target Neighborhood Hits	643	Shared Neighborhood Hits	40
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

CSPG2_HUMAN
NC score	0.102119 (rank : 110)	θ value	θ > 10 (rank : 103)
Query Neighborhood Hits	77	Target Neighborhood Hits	681	Shared Neighborhood Hits	49
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

IL2RA_HUMAN
NC score	0.102111 (rank : 111)	θ value	θ > 10 (rank : 137)
Query Neighborhood Hits	77	Target Neighborhood Hits	32	Shared Neighborhood Hits	18
SwissProt Accessions	P01589	Gene names	IL2RA
Domain Architecture
Description	Interleukin-2 receptor alpha chain precursor (IL-2 receptor alpha subunit) (IL-2-RA) (IL2-RA) (p55) (TAC antigen) (CD25 antigen).

KREM2_MOUSE
NC score	0.100006 (rank : 112)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	77	Target Neighborhood Hits	90	Shared Neighborhood Hits	14
SwissProt Accessions	Q8K1S7	Gene names	Kremen2
Domain Architecture
Description	Kremen protein 2 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 2) (Dickkopf receptor 2).

PGCA_HUMAN
NC score	0.096635 (rank : 113)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	77	Target Neighborhood Hits	821	Shared Neighborhood Hits	45
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

DCBD2_HUMAN
NC score	0.094881 (rank : 114)	θ value	θ > 10 (rank : 113)
Query Neighborhood Hits	77	Target Neighborhood Hits	118	Shared Neighborhood Hits	16
SwissProt Accessions	Q96PD2, Q8N6M4, Q8TDX2	Gene names	DCBLD2, CLCP1, ESDN
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein) (CUB, LCCL and coagulation factor V/VIII-homology domains protein 1).

DMBT1_HUMAN
NC score	0.092954 (rank : 115)	θ value	θ > 10 (rank : 116)
Query Neighborhood Hits	77	Target Neighborhood Hits	152	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UGM3, Q59EX0, Q5JR26, Q6MZN4, Q96DU4, Q9UGM2, Q9UJ57, Q9UKJ4, Q9Y211, Q9Y4V9	Gene names	DMBT1, GP340
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (Glycoprotein 340) (Gp-340) (Surfactant pulmonary-associated D-binding protein).

ATRN_HUMAN
NC score	0.090874 (rank : 116)	θ value	θ > 10 (rank : 83)
Query Neighborhood Hits	77	Target Neighborhood Hits	525	Shared Neighborhood Hits	20
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

ATRN_MOUSE
NC score	0.090371 (rank : 117)	θ value	8.99809 (rank : 76)
Query Neighborhood Hits	77	Target Neighborhood Hits	519	Shared Neighborhood Hits	22
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

LRP3_HUMAN
NC score	0.087664 (rank : 118)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	77	Target Neighborhood Hits	280	Shared Neighborhood Hits	23
SwissProt Accessions	O75074	Gene names	LRP3
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 3 precursor (hLRp105).

ST14_MOUSE
NC score	0.087476 (rank : 119)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	77	Target Neighborhood Hits	419	Shared Neighborhood Hits	26
SwissProt Accessions	P56677	Gene names	St14, Prss14
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Epithin).

PGCB_MOUSE
NC score	0.087330 (rank : 120)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	77	Target Neighborhood Hits	459	Shared Neighborhood Hits	47
SwissProt Accessions	Q61361	Gene names	Bcan
Domain Architecture
Description	Brevican core protein precursor.

DCBD2_MOUSE
NC score	0.086935 (rank : 121)	θ value	θ > 10 (rank : 114)
Query Neighborhood Hits	77	Target Neighborhood Hits	113	Shared Neighborhood Hits	16
SwissProt Accessions	Q91ZV3, Q8BKI4	Gene names	Dcbld2, Esdn
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein).

DCBD1_HUMAN
NC score	0.086703 (rank : 122)	θ value	θ > 10 (rank : 111)
Query Neighborhood Hits	77	Target Neighborhood Hits	110	Shared Neighborhood Hits	15
SwissProt Accessions	Q8N8Z6, Q5H992, Q8IYK5, Q8N7L9, Q96NH2	Gene names	DCBLD1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

ENTK_MOUSE
NC score	0.085649 (rank : 123)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	77	Target Neighborhood Hits	338	Shared Neighborhood Hits	21
SwissProt Accessions	P97435	Gene names	Prss7, Entk
Domain Architecture
Description	Enteropeptidase (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

ST14_HUMAN
NC score	0.085497 (rank : 124)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	77	Target Neighborhood Hits	409	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y5Y6, Q9BS01, Q9H3S0, Q9HB36, Q9HCA3	Gene names	ST14, PRSS14, SNC19, TADG15
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Matriptase) (Membrane-type serine protease 1) (MT-SP1) (Prostamin) (Serine protease TADG-15) (Tumor-associated differentially-expressed gene 15 protein).

ENTK_HUMAN
NC score	0.083200 (rank : 125)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	77	Target Neighborhood Hits	310	Shared Neighborhood Hits	22
SwissProt Accessions	P98073	Gene names	PRSS7, ENTK
Domain Architecture
Description	Enteropeptidase precursor (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

GP126_HUMAN
NC score	0.081924 (rank : 126)	θ value	θ > 10 (rank : 129)
Query Neighborhood Hits	77	Target Neighborhood Hits	187	Shared Neighborhood Hits	16
SwissProt Accessions	Q86SQ4, Q6MZU7, Q8NC14, Q96JW0	Gene names	GPR126
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 126 precursor.

HPT_MOUSE
NC score	0.080337 (rank : 127)	θ value	θ > 10 (rank : 136)
Query Neighborhood Hits	77	Target Neighborhood Hits	178	Shared Neighborhood Hits	19
SwissProt Accessions	Q61646	Gene names	Hp
Domain Architecture
Description	Haptoglobin precursor [Contains: Haptoglobin alpha chain; Haptoglobin beta chain].

HPTR_HUMAN
NC score	0.078274 (rank : 128)	θ value	θ > 10 (rank : 134)
Query Neighborhood Hits	77	Target Neighborhood Hits	166	Shared Neighborhood Hits	15
SwissProt Accessions	P00739, Q7LE20, Q92658, Q92659, Q9ULB0	Gene names	HPR
Domain Architecture
Description	Haptoglobin-related protein precursor.

FA10_HUMAN
NC score	0.078037 (rank : 129)	θ value	θ > 10 (rank : 120)
Query Neighborhood Hits	77	Target Neighborhood Hits	431	Shared Neighborhood Hits	29
SwissProt Accessions	P00742, Q14340	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) (Stuart- Prower factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

FA10_MOUSE
NC score	0.077410 (rank : 130)	θ value	θ > 10 (rank : 121)
Query Neighborhood Hits	77	Target Neighborhood Hits	435	Shared Neighborhood Hits	29
SwissProt Accessions	O88947, O54740, Q99L32	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

PROZ_MOUSE
NC score	0.077120 (rank : 131)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	77	Target Neighborhood Hits	410	Shared Neighborhood Hits	31
SwissProt Accessions	Q9CQW3	Gene names	Proz
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

PROC_MOUSE
NC score	0.075021 (rank : 132)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	77	Target Neighborhood Hits	426	Shared Neighborhood Hits	29
SwissProt Accessions	P33587, O35498, Q91WN8, Q99PC6	Gene names	Proc
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

PROZ_HUMAN
NC score	0.074558 (rank : 133)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	77	Target Neighborhood Hits	422	Shared Neighborhood Hits	31
SwissProt Accessions	P22891, Q15213	Gene names	PROZ
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

PROC_HUMAN
NC score	0.071066 (rank : 134)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	77	Target Neighborhood Hits	406	Shared Neighborhood Hits	27
SwissProt Accessions	P04070, Q15189, Q15190, Q16001	Gene names	PROC
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

FA9_HUMAN
NC score	0.065755 (rank : 135)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	77	Target Neighborhood Hits	421	Shared Neighborhood Hits	27
SwissProt Accessions	P00740	Gene names	F9
Domain Architecture
Description	Coagulation factor IX precursor (EC 3.4.21.22) (Christmas factor) (Plasma thromboplastin component) (PTC) [Contains: Coagulation factor IXa light chain; Coagulation factor IXa heavy chain].

CLC4K_HUMAN
NC score	0.065449 (rank : 136)	θ value	θ > 10 (rank : 99)
Query Neighborhood Hits	77	Target Neighborhood Hits	172	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UJ71	Gene names	CD207, CLEC4K
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 4 member K (Langerin) (CD207 antigen).

THRB_HUMAN
NC score	0.064102 (rank : 137)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	77	Target Neighborhood Hits	196	Shared Neighborhood Hits	15
SwissProt Accessions	P00734	Gene names	F2
Domain Architecture
Description	Prothrombin precursor (EC 3.4.21.5) (Coagulation factor II) [Contains: Activation peptide fragment 1; Activation peptide fragment 2; Thrombin light chain; Thrombin heavy chain].

FA7_HUMAN
NC score	0.064056 (rank : 138)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	77	Target Neighborhood Hits	404	Shared Neighborhood Hits	25
SwissProt Accessions	P08709, Q14339, Q5JVF2	Gene names	F7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) (SPCA) (Proconvertin) (Eptacog alfa) [Contains: Factor VII light chain; Factor VII heavy chain].

THRB_MOUSE
NC score	0.063949 (rank : 139)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	77	Target Neighborhood Hits	195	Shared Neighborhood Hits	15
SwissProt Accessions	P19221	Gene names	F2, Cf2
Domain Architecture
Description	Prothrombin precursor (EC 3.4.21.5) (Coagulation factor II) [Contains: Activation peptide fragment 1; Activation peptide fragment 2; Thrombin light chain; Thrombin heavy chain].

CLC4K_MOUSE
NC score	0.063924 (rank : 140)	θ value	θ > 10 (rank : 100)
Query Neighborhood Hits	77	Target Neighborhood Hits	165	Shared Neighborhood Hits	7
SwissProt Accessions	Q8VBX4, Q8R442	Gene names	Cd207, Clec4k
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 4 member K (Langerin) (CD207 antigen).

TMPS6_HUMAN
NC score	0.063309 (rank : 141)	θ value	θ > 10 (rank : 207)
Query Neighborhood Hits	77	Target Neighborhood Hits	338	Shared Neighborhood Hits	23
SwissProt Accessions	Q8IU80, Q5TI06, Q6UXD8, Q8IUE2, Q8IXV8	Gene names	TMPRSS6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

TMPS6_MOUSE
NC score	0.062436 (rank : 142)	θ value	θ > 10 (rank : 208)
Query Neighborhood Hits	77	Target Neighborhood Hits	341	Shared Neighborhood Hits	20
SwissProt Accessions	Q9DBI0, Q6PF94	Gene names	Tmprss6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

TMPS7_MOUSE
NC score	0.061925 (rank : 143)	θ value	θ > 10 (rank : 210)
Query Neighborhood Hits	77	Target Neighborhood Hits	275	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BIK6	Gene names	Tmprss7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

SCUB3_HUMAN
NC score	0.061381 (rank : 144)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	77	Target Neighborhood Hits	428	Shared Neighborhood Hits	33
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

TMPS7_HUMAN
NC score	0.060340 (rank : 145)	θ value	θ > 10 (rank : 209)
Query Neighborhood Hits	77	Target Neighborhood Hits	275	Shared Neighborhood Hits	20
SwissProt Accessions	Q7RTY8	Gene names	TMPRSS7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

SCUB3_MOUSE
NC score	0.059693 (rank : 146)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	77	Target Neighborhood Hits	442	Shared Neighborhood Hits	32
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

FA7_MOUSE
NC score	0.059146 (rank : 147)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	77	Target Neighborhood Hits	374	Shared Neighborhood Hits	23
SwissProt Accessions	P70375, Q61109	Gene names	F7, Cf7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) [Contains: Factor VII light chain; Factor VII heavy chain].

BSSP4_MOUSE
NC score	0.058036 (rank : 148)	θ value	θ > 10 (rank : 87)
Query Neighborhood Hits	77	Target Neighborhood Hits	179	Shared Neighborhood Hits	14
SwissProt Accessions	Q9ER10	Gene names	Prss22, Bssp4, Prss26
Domain Architecture
Description	Brain-specific serine protease 4 precursor (EC 3.4.21.-) (BSSP-4) (Serine protease 22) (Tryptase epsilon).

TEST_MOUSE
NC score	0.057555 (rank : 149)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	77	Target Neighborhood Hits	174	Shared Neighborhood Hits	14
SwissProt Accessions	Q9JHJ7, Q9DA14	Gene names	Prss21
Domain Architecture
Description	Testisin precursor (EC 3.4.21.-) (Tryptase 4).

CLC10_HUMAN
NC score	0.057325 (rank : 150)	θ value	θ > 10 (rank : 93)
Query Neighborhood Hits	77	Target Neighborhood Hits	134	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IUN9, Q14538, Q6PIW3	Gene names	CLEC10A, CLECSF14, HML
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 10 member A (C-type lectin superfamily member 14) (Macrophage lectin 2) (CD301 antigen).

TMPS4_MOUSE
NC score	0.057131 (rank : 151)	θ value	θ > 10 (rank : 204)
Query Neighborhood Hits	77	Target Neighborhood Hits	210	Shared Neighborhood Hits	14
SwissProt Accessions	Q8VCA5	Gene names	Tmprss4, Cap2
Domain Architecture
Description	Transmembrane protease, serine 4 (EC 3.4.21.-) (Channel-activating protease 2) (mCAP2).

HABP2_HUMAN
NC score	0.057100 (rank : 152)	θ value	θ > 10 (rank : 130)
Query Neighborhood Hits	77	Target Neighborhood Hits	431	Shared Neighborhood Hits	30
SwissProt Accessions	Q14520, O00663	Gene names	HABP2, HGFAL, PHBP
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) (Hepatocyte growth factor activator-like protein) (Factor VII-activating protease) (Factor seven-activating protease) (FSAP) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

TMSP8_MOUSE
NC score	0.057000 (rank : 153)	θ value	θ > 10 (rank : 215)
Query Neighborhood Hits	77	Target Neighborhood Hits	176	Shared Neighborhood Hits	14
SwissProt Accessions	Q9QYZ9, Q91XC4	Gene names	Tmprss8, Disp
Domain Architecture
Description	Transmembrane serine protease 8 precursor (EC 3.4.21.-) (Distal intestinal serine protease).

TMPS4_HUMAN
NC score	0.056954 (rank : 154)	θ value	θ > 10 (rank : 203)
Query Neighborhood Hits	77	Target Neighborhood Hits	203	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NRS4, Q5XKQ6, Q6UX37, Q9NZA5	Gene names	TMPRSS4, TMPRSS3
Domain Architecture
Description	Transmembrane protease, serine 4 (EC 3.4.21.-) (Membrane-type serine protease 2) (MT-SP2).

FA11_HUMAN
NC score	0.056798 (rank : 155)	θ value	θ > 10 (rank : 122)
Query Neighborhood Hits	77	Target Neighborhood Hits	178	Shared Neighborhood Hits	14
SwissProt Accessions	P03951, Q9Y495	Gene names	F11
Domain Architecture
Description	Coagulation factor XI precursor (EC 3.4.21.27) (Plasma thromboplastin antecedent) (PTA) (FXI) [Contains: Coagulation factor XIa heavy chain; Coagulation factor XIa light chain].

CLC4A_MOUSE
NC score	0.056713 (rank : 156)	θ value	θ > 10 (rank : 94)
Query Neighborhood Hits	77	Target Neighborhood Hits	103	Shared Neighborhood Hits	7
SwissProt Accessions	Q9QZ15, Q4VA33	Gene names	Clec4a, Clec4a2, Clecsf6, Dcir
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 4 member A (C-type lectin superfamily member 6) (Dendritic cell immunoreceptor).

TPA_HUMAN
NC score	0.056097 (rank : 157)	θ value	θ > 10 (rank : 216)
Query Neighborhood Hits	77	Target Neighborhood Hits	324	Shared Neighborhood Hits	19
SwissProt Accessions	P00750, Q15103, Q7Z7N2, Q86YK8, Q9BU99	Gene names	PLAT
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) (Alteplase) (Reteplase) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

PRSS8_HUMAN
NC score	0.056094 (rank : 158)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	77	Target Neighborhood Hits	177	Shared Neighborhood Hits	14
SwissProt Accessions	Q16651, Q9UCA3	Gene names	PRSS8
Domain Architecture
Description	Prostasin precursor (EC 3.4.21.-) [Contains: Prostasin light chain; Prostasin heavy chain].

PRS27_HUMAN
NC score	0.055886 (rank : 159)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	77	Target Neighborhood Hits	177	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BQR3	Gene names	PRSS27, MPN
Domain Architecture
Description	Protease serine 27 precursor (EC 3.4.21.-) (Marapsin) (Pancreasin) (Channel-activating protease 2) (CAPH2).

ASGR2_MOUSE
NC score	0.055804 (rank : 160)	θ value	θ > 10 (rank : 82)
Query Neighborhood Hits	77	Target Neighborhood Hits	123	Shared Neighborhood Hits	8
SwissProt Accessions	P24721	Gene names	Asgr2, Asgr-2
Domain Architecture
Description	Asialoglycoprotein receptor 2 (ASGP-R 2) (ASGPR 2) (Hepatic lectin 2) (MHL-2).

FA11_MOUSE
NC score	0.055781 (rank : 161)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	77	Target Neighborhood Hits	180	Shared Neighborhood Hits	14
SwissProt Accessions	Q91Y47	Gene names	F11
Domain Architecture
Description	Coagulation factor XI precursor (EC 3.4.21.27) (Plasma thromboplastin antecedent) (PTA) (FXI) [Contains: Coagulation factor XIa heavy chain; Coagulation factor XIa light chain].

TM11D_MOUSE
NC score	0.055519 (rank : 162)	θ value	θ > 10 (rank : 196)
Query Neighborhood Hits	77	Target Neighborhood Hits	179	Shared Neighborhood Hits	14
SwissProt Accessions	Q8VHK8, Q7TNX3, Q8VDV1	Gene names	Tmprss11d, Mat
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 11D precursor (EC 3.4.21.-) (Airway trypsin-like protease) (AT) (Adrenal secretory serine protease) (AsP) [Contains: Transmembrane protease, serine 11D non-catalytic chain; Transmembrane protease, serine 11D catalytic chain].

TSP50_HUMAN
NC score	0.054854 (rank : 163)	θ value	θ > 10 (rank : 225)
Query Neighborhood Hits	77	Target Neighborhood Hits	178	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UI38	Gene names	TSP50
Domain Architecture
Description	Testis-specific protease-like protein 50 precursor.

TMPSD_MOUSE
NC score	0.054796 (rank : 164)	θ value	θ > 10 (rank : 214)
Query Neighborhood Hits	77	Target Neighborhood Hits	334	Shared Neighborhood Hits	14
SwissProt Accessions	Q5U405, Q8CFE0, Q91VQ8	Gene names	Tmprss13, Msp
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).

TM11D_HUMAN
NC score	0.054789 (rank : 165)	θ value	θ > 10 (rank : 195)
Query Neighborhood Hits	77	Target Neighborhood Hits	176	Shared Neighborhood Hits	14
SwissProt Accessions	O60235	Gene names	TMPRSS11D, HAT
Domain Architecture
Description	Transmembrane protease, serine 11D precursor (EC 3.4.21.-) (Airway trypsin-like protease) [Contains: Transmembrane protease, serine 11D non-catalytic chain; Transmembrane protease, serine 11D catalytic chain].

KLKB1_MOUSE
NC score	0.054634 (rank : 166)	θ value	θ > 10 (rank : 141)
Query Neighborhood Hits	77	Target Neighborhood Hits	177	Shared Neighborhood Hits	14
SwissProt Accessions	P26262	Gene names	Klkb1, Klk3, Pk
Domain Architecture
Description	Plasma kallikrein precursor (EC 3.4.21.34) (Plasma prekallikrein) (Kininogenin) (Fletcher factor) [Contains: Plasma kallikrein heavy chain; Plasma kallikrein light chain].

KLKB1_HUMAN
NC score	0.054527 (rank : 167)	θ value	θ > 10 (rank : 140)
Query Neighborhood Hits	77	Target Neighborhood Hits	183	Shared Neighborhood Hits	14
SwissProt Accessions	P03952	Gene names	KLKB1, KLK3
Domain Architecture
Description	Plasma kallikrein precursor (EC 3.4.21.34) (Plasma prekallikrein) (Kininogenin) (Fletcher factor) [Contains: Plasma kallikrein heavy chain; Plasma kallikrein light chain].

DESC4_MOUSE
NC score	0.054506 (rank : 168)	θ value	θ > 10 (rank : 115)
Query Neighborhood Hits	77	Target Neighborhood Hits	176	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BZ10, Q8BZ04	Gene names	Desc4
Domain Architecture	No domain graphic available
Description	Serine protease DESC4 precursor (EC 3.4.21.-) [Contains: Serine protease DESC4 non-catalytic chain; Serine protease DESC4 catalytic chain].

MMGL_MOUSE
NC score	0.054247 (rank : 169)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	77	Target Neighborhood Hits	270	Shared Neighborhood Hits	9
SwissProt Accessions	P49300	Gene names	Mgl1, Mgl
Domain Architecture
Description	Macrophage asialoglycoprotein-binding protein 1 (M-ASGP-BP) (Macrophage galactose/N-acetylgalactosamine-specific lectin) (MMGL).

PRSS8_MOUSE
NC score	0.054238 (rank : 170)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	77	Target Neighborhood Hits	177	Shared Neighborhood Hits	14
SwissProt Accessions	Q9ESD1	Gene names	Prss8, Cap1
Domain Architecture
Description	Prostasin precursor (EC 3.4.21.-) (Channel-activating protease 1) [Contains: Prostasin light chain; Prostasin heavy chain].

TRYG1_HUMAN
NC score	0.054137 (rank : 171)	θ value	θ > 10 (rank : 221)
Query Neighborhood Hits	77	Target Neighborhood Hits	179	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NRR2, Q96RZ8, Q9C015, Q9NRQ8, Q9UBB2	Gene names	TPSG1, TMT
Domain Architecture
Description	Tryptase gamma precursor (EC 3.4.21.-) (Transmembrane tryptase) [Contains: Tryptase gamma light chain; Tryptase gamma heavy chain].

TPA_MOUSE
NC score	0.054043 (rank : 172)	θ value	θ > 10 (rank : 217)
Query Neighborhood Hits	77	Target Neighborhood Hits	335	Shared Neighborhood Hits	21
SwissProt Accessions	P11214, Q91VP2	Gene names	Plat
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

CLC4E_MOUSE
NC score	0.053961 (rank : 173)	θ value	θ > 10 (rank : 97)
Query Neighborhood Hits	77	Target Neighborhood Hits	113	Shared Neighborhood Hits	7
SwissProt Accessions	Q9R0Q8	Gene names	Clec4e, Clecsf9, Mincle
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 4 member E (C-type lectin superfamily member 9) (Macrophage-inducible C-type lectin).

FCER2_HUMAN
NC score	0.053926 (rank : 174)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	77	Target Neighborhood Hits	213	Shared Neighborhood Hits	6
SwissProt Accessions	P06734	Gene names	FCER2, IGEBF
Domain Architecture
Description	Low affinity immunoglobulin epsilon Fc receptor (Lymphocyte IgE receptor) (Fc-epsilon-RII) (BLAST-2) (Immunoglobulin E-binding factor) (CD23 antigen) [Contains: Low affinity immunoglobulin epsilon Fc receptor membrane-bound form; Low affinity immunoglobulin epsilon Fc receptor soluble form].

TMPSD_HUMAN
NC score	0.053788 (rank : 175)	θ value	θ > 10 (rank : 213)
Query Neighborhood Hits	77	Target Neighborhood Hits	333	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BYE2, Q86YM4, Q96JY8, Q9BYE1	Gene names	TMPRSS13, MSP, TMPRSS11
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).

BSSP4_HUMAN
NC score	0.053694 (rank : 176)	θ value	θ > 10 (rank : 86)
Query Neighborhood Hits	77	Target Neighborhood Hits	176	Shared Neighborhood Hits	14
SwissProt Accessions	Q9GZN4, O43342, Q6UXE0	Gene names	PRSS22, BSSP4, PRSS26
Domain Architecture
Description	Brain-specific serine protease 4 precursor (EC 3.4.21.-) (BSSP-4) (Serine protease 22) (Tryptase epsilon).

TMPS2_HUMAN
NC score	0.053552 (rank : 177)	θ value	θ > 10 (rank : 199)
Query Neighborhood Hits	77	Target Neighborhood Hits	252	Shared Neighborhood Hits	14
SwissProt Accessions	O15393, Q9BXX1	Gene names	TMPRSS2, PRSS10
Domain Architecture
Description	Transmembrane protease, serine 2 precursor (EC 3.4.21.-) [Contains: Transmembrane protease, serine 2 non-catalytic chain; Transmembrane protease, serine 2 catalytic chain].

TMPS2_MOUSE
NC score	0.053550 (rank : 178)	θ value	θ > 10 (rank : 200)
Query Neighborhood Hits	77	Target Neighborhood Hits	243	Shared Neighborhood Hits	16
SwissProt Accessions	Q9JIQ8, Q9JKC4, Q9QY82	Gene names	Tmprss2
Domain Architecture
Description	Transmembrane protease, serine 2 (EC 3.4.21.-) (Epitheliasin) (Plasmic transmembrane protein X) [Contains: Transmembrane protease, serine 2 non-catalytic chain; Transmembrane protease, serine 2 catalytic chain].

CFAI_HUMAN
NC score	0.053453 (rank : 179)	θ value	θ > 10 (rank : 91)
Query Neighborhood Hits	77	Target Neighborhood Hits	289	Shared Neighborhood Hits	19
SwissProt Accessions	P05156, O60442	Gene names	CFI, IF
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

ACRO_HUMAN
NC score	0.053211 (rank : 180)	θ value	θ > 10 (rank : 78)
Query Neighborhood Hits	77	Target Neighborhood Hits	291	Shared Neighborhood Hits	15
SwissProt Accessions	P10323, Q6ICK2	Gene names	ACR, ACRS
Domain Architecture
Description	Acrosin precursor (EC 3.4.21.10) [Contains: Acrosin light chain; Acrosin heavy chain].

ACRO_MOUSE
NC score	0.053118 (rank : 181)	θ value	θ > 10 (rank : 79)
Query Neighborhood Hits	77	Target Neighborhood Hits	185	Shared Neighborhood Hits	14
SwissProt Accessions	P23578	Gene names	Acr
Domain Architecture
Description	Acrosin precursor (EC 3.4.21.10) [Contains: Acrosin light chain; Acrosin heavy chain].

TMPS9_MOUSE
NC score	0.053074 (rank : 182)	θ value	θ > 10 (rank : 212)
Query Neighborhood Hits	77	Target Neighborhood Hits	296	Shared Neighborhood Hits	17
SwissProt Accessions	P69525	Gene names	Tmprss9
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 9 (EC 3.4.21.-) (Polyserase-1) (Polyserine protease 1) (Polyserase-I) [Contains: Serase-1; Serase-2; Serase-3].

TM11E_MOUSE
NC score	0.053023 (rank : 183)	θ value	θ > 10 (rank : 198)
Query Neighborhood Hits	77	Target Neighborhood Hits	176	Shared Neighborhood Hits	14
SwissProt Accessions	Q5S248, Q8BM10	Gene names	Tmprss11e, Desc1
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 11E precursor (EC 3.4.21.-) (Serine protease DESC1) [Contains: Transmembrane protease, serine 11E non- catalytic chain; Transmembrane protease, serine 11E catalytic chain].

C209A_MOUSE
NC score	0.053009 (rank : 184)	θ value	θ > 10 (rank : 88)
Query Neighborhood Hits	77	Target Neighborhood Hits	117	Shared Neighborhood Hits	7
SwissProt Accessions	Q91ZX1, Q3TAT9, Q91ZW5	Gene names	Cd209a, Cire
Domain Architecture
Description	CD209 antigen-like protein A (Dendritic cell-specific ICAM-3-grabbing nonintegrin) (DC-SIGN).

ASGR2_HUMAN
NC score	0.052995 (rank : 185)	θ value	θ > 10 (rank : 81)
Query Neighborhood Hits	77	Target Neighborhood Hits	121	Shared Neighborhood Hits	6
SwissProt Accessions	P07307, O00448, Q03969	Gene names	ASGR2
Domain Architecture
Description	Asialoglycoprotein receptor 2 (ASGP-R 2) (ASGPR 2) (Hepatic lectin H2).

PRS27_MOUSE
NC score	0.052876 (rank : 186)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	77	Target Neighborhood Hits	175	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BJR6	Gene names	Prss27, Mpn
Domain Architecture	No domain graphic available
Description	Protease serine 27 precursor (EC 3.4.21.-) (Marapsin) (Pancreasin).

ASGR1_MOUSE
NC score	0.052654 (rank : 187)	θ value	θ > 10 (rank : 80)
Query Neighborhood Hits	77	Target Neighborhood Hits	135	Shared Neighborhood Hits	8
SwissProt Accessions	P34927, Q64363	Gene names	Asgr1, Asgr-1
Domain Architecture
Description	Asialoglycoprotein receptor 1 (ASGPR 1) (ASGP-R 1) (Hepatic lectin 1) (MHL-1).

CLC4G_MOUSE
NC score	0.052488 (rank : 188)	θ value	θ > 10 (rank : 98)
Query Neighborhood Hits	77	Target Neighborhood Hits	155	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BNX1, Q5I0T7, Q8R188	Gene names	Clec4g
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 4 member G.

TMPS9_HUMAN
NC score	0.052471 (rank : 189)	θ value	θ > 10 (rank : 211)
Query Neighborhood Hits	77	Target Neighborhood Hits	276	Shared Neighborhood Hits	17
SwissProt Accessions	Q7Z410, Q6ZND6, Q7Z411	Gene names	TMPRSS9
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 9 (EC 3.4.21.-) (Polyserase-1) (Polyserase-I) (Polyserine protease 1) [Contains: Serase-1; Serase-2; Serase-3].

FA12_HUMAN
NC score	0.052443 (rank : 190)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	77	Target Neighborhood Hits	425	Shared Neighborhood Hits	27
SwissProt Accessions	P00748, P78339	Gene names	F12
Domain Architecture
Description	Coagulation factor XII precursor (EC 3.4.21.38) (Hageman factor) (HAF) [Contains: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Beta-factor XIIa part 2; Coagulation factor XIIa light chain].

TRYG1_MOUSE
NC score	0.052094 (rank : 191)	θ value	θ > 10 (rank : 222)
Query Neighborhood Hits	77	Target Neighborhood Hits	181	Shared Neighborhood Hits	14
SwissProt Accessions	Q9QUL7	Gene names	Tpsg1, Tmt
Domain Architecture
Description	Tryptase gamma precursor (EC 3.4.21.-) (Transmembrane tryptase) [Contains: Tryptase gamma light chain; Tryptase gamma heavy chain].

HEPS_MOUSE
NC score	0.052055 (rank : 192)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	77	Target Neighborhood Hits	178	Shared Neighborhood Hits	14
SwissProt Accessions	O35453, Q9CW97	Gene names	Hpn
Domain Architecture
Description	Serine protease hepsin (EC 3.4.21.-) [Contains: Serine protease hepsin non-catalytic chain; Serine protease hepsin catalytic chain].

C209E_MOUSE
NC score	0.052029 (rank : 193)	θ value	θ > 10 (rank : 90)
Query Neighborhood Hits	77	Target Neighborhood Hits	117	Shared Neighborhood Hits	7
SwissProt Accessions	Q91ZW7	Gene names	Cd209e
Domain Architecture
Description	CD209 antigen-like protein E (DC-SIGN-related protein 4) (DC-SIGNR4).

TMPS5_HUMAN
NC score	0.051961 (rank : 194)	θ value	θ > 10 (rank : 205)
Query Neighborhood Hits	77	Target Neighborhood Hits	181	Shared Neighborhood Hits	14
SwissProt Accessions	Q9H3S3	Gene names	TMPRSS5
Domain Architecture
Description	Transmembrane protease, serine 5 (EC 3.4.21.-) (Spinesin).

TMPS3_MOUSE
NC score	0.051880 (rank : 195)	θ value	θ > 10 (rank : 202)
Query Neighborhood Hits	77	Target Neighborhood Hits	239	Shared Neighborhood Hits	16
SwissProt Accessions	Q8K1T0, Q8VDE0	Gene names	Tmprss3
Domain Architecture
Description	Transmembrane protease, serine 3 (EC 3.4.21.-).

TM11E_HUMAN
NC score	0.051722 (rank : 196)	θ value	θ > 10 (rank : 197)
Query Neighborhood Hits	77	Target Neighborhood Hits	181	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UL52, Q6UW31	Gene names	TMPRSS11E, DESC1
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 11E precursor (EC 3.4.21.-) (Serine protease DESC1) [Contains: Transmembrane protease, serine 11E non- catalytic chain; Transmembrane protease, serine 11E catalytic chain].

CFAI_MOUSE
NC score	0.051640 (rank : 197)	θ value	θ > 10 (rank : 92)
Query Neighborhood Hits	77	Target Neighborhood Hits	290	Shared Neighborhood Hits	18
SwissProt Accessions	Q61129, Q9WU07	Gene names	Cfi, If
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

HEPS_HUMAN
NC score	0.051639 (rank : 198)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	77	Target Neighborhood Hits	178	Shared Neighborhood Hits	14
SwissProt Accessions	P05981	Gene names	HPN, TMPRSS1
Domain Architecture
Description	Serine protease hepsin (EC 3.4.21.-) (Transmembrane protease, serine 1) [Contains: Serine protease hepsin non-catalytic chain; Serine protease hepsin catalytic chain].

MRC1_HUMAN
NC score	0.051566 (rank : 199)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	77	Target Neighborhood Hits	157	Shared Neighborhood Hits	8
SwissProt Accessions	P22897	Gene names	MRC1
Domain Architecture
Description	Macrophage mannose receptor 1 precursor (MMR) (CD206 antigen).

LTBP2_HUMAN
NC score	0.051482 (rank : 200)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	77	Target Neighborhood Hits	552	Shared Neighborhood Hits	39
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

MCPT6_MOUSE
NC score	0.051346 (rank : 201)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	77	Target Neighborhood Hits	175	Shared Neighborhood Hits	14
SwissProt Accessions	P21845, Q61962	Gene names	Mcpt6
Domain Architecture
Description	Mast cell protease 6 precursor (EC 3.4.21.59) (MMCP-6) (Tryptase).

TEST_HUMAN
NC score	0.051295 (rank : 202)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	77	Target Neighborhood Hits	172	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y6M0, Q9NS34, Q9P2V6	Gene names	PRSS21, ESP1, TEST1
Domain Architecture
Description	Testisin precursor (EC 3.4.21.-) (Eosinophil serine protease 1) (ESP- 1).

CLC4C_HUMAN
NC score	0.051031 (rank : 203)	θ value	θ > 10 (rank : 95)
Query Neighborhood Hits	77	Target Neighborhood Hits	111	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WTT0, Q3T1C3, Q6UXS8, Q8WXX8	Gene names	CLEC4C, BDCA2, CLECSF11, CLECSF7, DLEC, HECL
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 4 member C (C-type lectin superfamily member 7) (Blood dendritic cell antigen 2 protein) (BDCA-2) (Dendritic lectin) (CD303 antigen).

CORIN_HUMAN
NC score	0.050918 (rank : 204)	θ value	θ > 10 (rank : 102)
Query Neighborhood Hits	77	Target Neighborhood Hits	453	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y5Q5, Q9UHY2	Gene names	CORIN, CRN, TMPRSS10
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Heart-specific serine proteinase ATC2) (Transmembrane protease, serine 10).

TRYB1_HUMAN
NC score	0.050670 (rank : 205)	θ value	θ > 10 (rank : 218)
Query Neighborhood Hits	77	Target Neighborhood Hits	175	Shared Neighborhood Hits	14
SwissProt Accessions	Q15661, Q15663, Q9H2Y4	Gene names	TPSAB1, TPSB1
Domain Architecture
Description	Tryptase beta-1 precursor (EC 3.4.21.59) (Tryptase-1) (Tryptase I).

TRYB2_HUMAN
NC score	0.050670 (rank : 206)	θ value	θ > 10 (rank : 220)
Query Neighborhood Hits	77	Target Neighborhood Hits	175	Shared Neighborhood Hits	14
SwissProt Accessions	P20231, O95827, Q15664, Q9UQI6, Q9UQI7	Gene names	TPSB2, TPS2
Domain Architecture
Description	Tryptase beta-2 precursor (EC 3.4.21.59) (Tryptase-2) (Tryptase II).

TMPS3_HUMAN
NC score	0.050586 (rank : 207)	θ value	θ > 10 (rank : 201)
Query Neighborhood Hits	77	Target Neighborhood Hits	245	Shared Neighborhood Hits	15
SwissProt Accessions	P57727, Q6ZMC3	Gene names	TMPRSS3, ECHOS1, TADG12
Domain Architecture
Description	Transmembrane protease, serine 3 (EC 3.4.21.-) (Serine protease TADG- 12) (Tumor-associated differentially-expressed gene 12 protein).

C209C_MOUSE
NC score	0.050499 (rank : 208)	θ value	θ > 10 (rank : 89)
Query Neighborhood Hits	77	Target Neighborhood Hits	114	Shared Neighborhood Hits	6
SwissProt Accessions	Q91ZW9	Gene names	Cd209c
Domain Architecture
Description	CD209 antigen-like protein C (DC-SIGN-related protein 2) (DC-SIGNR2).

TMPS5_MOUSE
NC score	0.050457 (rank : 209)	θ value	θ > 10 (rank : 206)
Query Neighborhood Hits	77	Target Neighborhood Hits	185	Shared Neighborhood Hits	14
SwissProt Accessions	Q9ER04, Q9ER02, Q9ER03	Gene names	Tmprss5
Domain Architecture
Description	Transmembrane protease, serine 5 (EC 3.4.21.-) (Spinesin).

SFTPA_MOUSE
NC score	0.050300 (rank : 210)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	77	Target Neighborhood Hits	169	Shared Neighborhood Hits	6
SwissProt Accessions	P35242	Gene names	Sftpa1, Sftp-1, Sftp1, Sftpa
Domain Architecture
Description	Pulmonary surfactant-associated protein A precursor (SP-A) (PSP-A) (PSAP).

POLS2_MOUSE
NC score	0.050292 (rank : 211)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	77	Target Neighborhood Hits	188	Shared Neighborhood Hits	15
SwissProt Accessions	Q5K2P8	Gene names	Prss36
Domain Architecture	No domain graphic available
Description	Polyserase-2 precursor (EC 3.4.21.-) (Polyserine protease 2) (Protease serine 36).

TRYB1_MOUSE
NC score	0.050211 (rank : 212)	θ value	θ > 10 (rank : 219)
Query Neighborhood Hits	77	Target Neighborhood Hits	175	Shared Neighborhood Hits	14
SwissProt Accessions	Q02844	Gene names	Tpsab1, Mcpt7
Domain Architecture
Description	Tryptase precursor (EC 3.4.21.59) (Mast cell protease 7) (MMCP-7) (Tryptase alpha/beta-1).

CLC4E_HUMAN
NC score	0.050191 (rank : 213)	θ value	θ > 10 (rank : 96)
Query Neighborhood Hits	77	Target Neighborhood Hits	104	Shared Neighborhood Hits	7
SwissProt Accessions	Q9ULY5	Gene names	CLEC4E, CLECSF9, MINCLE
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 4 member E (C-type lectin superfamily member 9) (Macrophage-inducible C-type lectin).

CLCR_HUMAN
NC score	0.050175 (rank : 214)	θ value	θ > 10 (rank : 101)
Query Neighborhood Hits	77	Target Neighborhood Hits	177	Shared Neighborhood Hits	14
SwissProt Accessions	Q99895, O00765, Q9NUH5	Gene names	CTRC, CLCR
Domain Architecture
Description	Caldecrin precursor (EC 3.4.21.2) (Chymotrypsin C).

HABP2_MOUSE
NC score	0.050136 (rank : 215)	θ value	θ > 10 (rank : 131)
Query Neighborhood Hits	77	Target Neighborhood Hits	445	Shared Neighborhood Hits	32
SwissProt Accessions	Q8K0D2	Gene names	Habp2, Phbp
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

K1KB9_MOUSE
NC score	0.050113 (rank : 216)	θ value	θ > 10 (rank : 139)
Query Neighborhood Hits	77	Target Neighborhood Hits	176	Shared Neighborhood Hits	14
SwissProt Accessions	P15949	Gene names	Klk1b9, Egfbp3, Klk-9, Klk9
Domain Architecture
Description	Kallikrein 1-related peptidase b9 precursor (EC 3.4.21.35) (Tissue kallikrein-9) (Glandular kallikrein K9) (mGK-9) (Epidermal growth factor-binding protein type C) (EGF-BP C).

FBLN5_MOUSE
NC score	0.046182 (rank : 217)	θ value	8.99809 (rank : 77)
Query Neighborhood Hits	77	Target Neighborhood Hits	317	Shared Neighborhood Hits	30
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

PROS_HUMAN
NC score	0.043231 (rank : 218)	θ value	6.88961 (rank : 75)
Query Neighborhood Hits	77	Target Neighborhood Hits	340	Shared Neighborhood Hits	29
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

C1QR1_HUMAN
NC score	0.039724 (rank : 219)	θ value	5.27518 (rank : 72)
Query Neighborhood Hits	77	Target Neighborhood Hits	493	Shared Neighborhood Hits	29
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

LAMB2_MOUSE
NC score	0.038964 (rank : 220)	θ value	0.0961366 (rank : 62)
Query Neighborhood Hits	77	Target Neighborhood Hits	722	Shared Neighborhood Hits	19
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

LAMB2_HUMAN
NC score	0.037172 (rank : 221)	θ value	0.0431538 (rank : 59)
Query Neighborhood Hits	77	Target Neighborhood Hits	692	Shared Neighborhood Hits	19
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

FBLN3_MOUSE
NC score	0.034801 (rank : 222)	θ value	6.88961 (rank : 73)
Query Neighborhood Hits	77	Target Neighborhood Hits	279	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

LAMA2_HUMAN
NC score	0.031161 (rank : 223)	θ value	3.0926 (rank : 69)
Query Neighborhood Hits	77	Target Neighborhood Hits	1092	Shared Neighborhood Hits	22
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LAMB1_MOUSE
NC score	0.028551 (rank : 224)	θ value	6.88961 (rank : 74)
Query Neighborhood Hits	77	Target Neighborhood Hits	919	Shared Neighborhood Hits	18
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

MYH3_HUMAN
NC score	-0.002103 (rank : 225)	θ value	4.03905 (rank : 71)
Query Neighborhood Hits	77	Target Neighborhood Hits	1660	Shared Neighborhood Hits	6
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).