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Network neighborhood for query Sequence : GABR1_HUMAN

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GABR1_HUMAN
SwissProt Accessions	Q9UBS5, O95375, O95468, O95975, O96022, Q86W60, Q9UQQ0	Gene names	GABBR1, GPRC3A
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 1 precursor (GABA-B receptor 1) (GABA-B-R1) (Gb1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

GABR1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	142	Target Neighborhood Hits	142	Shared Neighborhood Hits	142
SwissProt Accessions	Q9UBS5, O95375, O95468, O95975, O96022, Q86W60, Q9UQQ0	Gene names	GABBR1, GPRC3A
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 1 precursor (GABA-B receptor 1) (GABA-B-R1) (Gb1).

GABR1_MOUSE
θ value	0 (rank : 2)	NC score	0.999599 (rank : 2)
Query Neighborhood Hits	142	Target Neighborhood Hits	139	Shared Neighborhood Hits	138
SwissProt Accessions	Q9WV18, Q9WU48, Q9WV15, Q9WV16, Q9WV17	Gene names	Gabbr1
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 1 precursor (GABA-B receptor 1) (GABA-B-R1) (Gb1).

GABR2_HUMAN
θ value	1.02419e-128 (rank : 3)	NC score	0.841848 (rank : 3)
Query Neighborhood Hits	142	Target Neighborhood Hits	101	Shared Neighborhood Hits	42
SwissProt Accessions	O75899, O75974, O75975, Q5VXZ2, Q8WX04, Q9P1R2, Q9UNR1, Q9UNS9	Gene names	GABBR2, GPR51, GPRC3B
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 2 precursor (GABA-B receptor 2) (GABA-B-R2) (Gb2) (GABABR2) (G-protein coupled receptor 51) (HG20).

GP156_HUMAN
θ value	2.20605e-14 (rank : 4)	NC score	0.446619 (rank : 4)
Query Neighborhood Hits	142	Target Neighborhood Hits	84	Shared Neighborhood Hits	13
SwissProt Accessions	Q8NFN8, Q86SN6	Gene names	GPR156, GABABL, PGR28
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 156 (GABAB-related G-protein coupled receptor) (G-protein coupled receptor PGR28).

ANPRB_MOUSE
θ value	2.28291e-11 (rank : 5)	NC score	0.143530 (rank : 79)
Query Neighborhood Hits	142	Target Neighborhood Hits	607	Shared Neighborhood Hits	18
SwissProt Accessions	Q6VVW5, Q6VVW3, Q6VVW4, Q8CGA9	Gene names	Npr2
Domain Architecture	No domain graphic available
Description	Atrial natriuretic peptide receptor B precursor (ANP-B) (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor).

ANPRB_HUMAN
θ value	1.47974e-10 (rank : 6)	NC score	0.136526 (rank : 81)
Query Neighborhood Hits	142	Target Neighborhood Hits	646	Shared Neighborhood Hits	19
SwissProt Accessions	P20594, O60871, Q9UQ50	Gene names	NPR2, ANPRB
Domain Architecture
Description	Atrial natriuretic peptide receptor B precursor (ANP-B) (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor).

MGR8_MOUSE
θ value	6.21693e-09 (rank : 7)	NC score	0.427172 (rank : 8)
Query Neighborhood Hits	142	Target Neighborhood Hits	44	Shared Neighborhood Hits	30
SwissProt Accessions	P47743, Q6B964	Gene names	Grm8, Gprc1h, Mglur8
Domain Architecture
Description	Metabotropic glutamate receptor 8 precursor (mGluR8).

MGR8_HUMAN
θ value	8.11959e-09 (rank : 8)	NC score	0.426484 (rank : 10)
Query Neighborhood Hits	142	Target Neighborhood Hits	49	Shared Neighborhood Hits	30
SwissProt Accessions	O00222, O15493, O95945, O95946, Q3MIV9, Q52M02, Q6J165	Gene names	GRM8, GPRC1H, MGLUR8
Domain Architecture
Description	Metabotropic glutamate receptor 8 precursor (mGluR8).

TS1R3_HUMAN
θ value	1.38499e-08 (rank : 9)	NC score	0.438617 (rank : 5)
Query Neighborhood Hits	142	Target Neighborhood Hits	46	Shared Neighborhood Hits	30
SwissProt Accessions	Q7RTX0, Q5TA49, Q8NGW9	Gene names	TAS1R3, T1R3, TR3
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 3 precursor (Sweet taste receptor T1R3).

MGR4_HUMAN
θ value	1.80886e-08 (rank : 10)	NC score	0.430625 (rank : 7)
Query Neighborhood Hits	142	Target Neighborhood Hits	63	Shared Neighborhood Hits	35
SwissProt Accessions	Q14833, Q5SZ84	Gene names	GRM4, GPRC1D, MGLUR4
Domain Architecture
Description	Metabotropic glutamate receptor 4 precursor (mGluR4).

ANPRA_MOUSE
θ value	1.53129e-07 (rank : 11)	NC score	0.127195 (rank : 86)
Query Neighborhood Hits	142	Target Neighborhood Hits	600	Shared Neighborhood Hits	15
SwissProt Accessions	P18293	Gene names	Npr1, Npra
Domain Architecture
Description	Atrial natriuretic peptide receptor A precursor (ANP-A) (ANPRA) (GC-A) (Guanylate cyclase) (EC 4.6.1.2) (NPR-A) (Atrial natriuretic peptide A-type receptor).

MGR7_HUMAN
θ value	1.53129e-07 (rank : 12)	NC score	0.425525 (rank : 12)
Query Neighborhood Hits	142	Target Neighborhood Hits	52	Shared Neighborhood Hits	30
SwissProt Accessions	Q14831, Q8NFS2, Q8NFS3, Q8NFS4	Gene names	GRM7, GPRC1G, MGLUR7
Domain Architecture
Description	Metabotropic glutamate receptor 7 precursor (mGluR7).

MGR7_MOUSE
θ value	1.53129e-07 (rank : 13)	NC score	0.425845 (rank : 11)
Query Neighborhood Hits	142	Target Neighborhood Hits	53	Shared Neighborhood Hits	31
SwissProt Accessions	Q68ED2	Gene names	Grm7, Gprc1g, Mglur7
Domain Architecture	No domain graphic available
Description	Metabotropic glutamate receptor 7 precursor (mGluR7).

TS1R1_HUMAN
θ value	1.53129e-07 (rank : 14)	NC score	0.431342 (rank : 6)
Query Neighborhood Hits	142	Target Neighborhood Hits	72	Shared Neighborhood Hits	35
SwissProt Accessions	Q7RTX1, Q8NGZ7, Q8TDJ7, Q8TDJ8, Q8TDJ9, Q8TDK0	Gene names	TAS1R1, GPR70, T1R1, TR1
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 1 precursor (G-protein coupled receptor 70) (Gm148).

GP156_MOUSE
θ value	1.99992e-07 (rank : 15)	NC score	0.393056 (rank : 29)
Query Neighborhood Hits	142	Target Neighborhood Hits	95	Shared Neighborhood Hits	14
SwissProt Accessions	Q6PCP7, Q8K452	Gene names	Gpr156, Gababl
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 156 (GABAB-related G-protein coupled receptor).

DAF_HUMAN
θ value	4.45536e-07 (rank : 16)	NC score	0.354203 (rank : 30)
Query Neighborhood Hits	142	Target Neighborhood Hits	97	Shared Neighborhood Hits	50
SwissProt Accessions	P08174, P09679, P78361	Gene names	CD55, CR, DAF
Domain Architecture
Description	Complement decay-accelerating factor precursor (CD55 antigen).

ANPRA_HUMAN
θ value	5.81887e-07 (rank : 17)	NC score	0.125362 (rank : 87)
Query Neighborhood Hits	142	Target Neighborhood Hits	612	Shared Neighborhood Hits	16
SwissProt Accessions	P16066, Q6P4Q3	Gene names	NPR1, ANPRA
Domain Architecture
Description	Atrial natriuretic peptide receptor A precursor (ANP-A) (ANPRA) (GC-A) (Guanylate cyclase) (EC 4.6.1.2) (NPR-A) (Atrial natriuretic peptide A-type receptor).

CSMD3_HUMAN
θ value	2.21117e-06 (rank : 18)	NC score	0.266177 (rank : 59)
Query Neighborhood Hits	142	Target Neighborhood Hits	199	Shared Neighborhood Hits	48
SwissProt Accessions	Q7Z407, Q96PZ3	Gene names	CSMD3, KIAA1894
Domain Architecture
Description	CUB and sushi domain-containing protein 3 precursor (CUB and sushi multiple domains protein 3).

CASR_HUMAN
θ value	4.92598e-06 (rank : 19)	NC score	0.412987 (rank : 16)
Query Neighborhood Hits	142	Target Neighborhood Hits	71	Shared Neighborhood Hits	29
SwissProt Accessions	P41180, Q13912, Q16108, Q16109, Q16110, Q16379, Q4PJ19	Gene names	CASR, GPRC2A, PCAR1
Domain Architecture
Description	Extracellular calcium-sensing receptor precursor (CaSR) (Parathyroid Cell calcium-sensing receptor).

V2RX_MOUSE
θ value	4.92598e-06 (rank : 20)	NC score	0.414804 (rank : 13)
Query Neighborhood Hits	142	Target Neighborhood Hits	45	Shared Neighborhood Hits	29
SwissProt Accessions	O70410	Gene names
Domain Architecture	No domain graphic available
Description	Vomeronasal type-2 receptor X precursor (Putative pheromone receptor V2RX).

CSMD1_HUMAN
θ value	6.43352e-06 (rank : 21)	NC score	0.260964 (rank : 60)
Query Neighborhood Hits	142	Target Neighborhood Hits	176	Shared Neighborhood Hits	48
SwissProt Accessions	Q96PZ7, Q96QU9, Q96RM4	Gene names	CSMD1, KIAA1890
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

MGR6_HUMAN
θ value	6.43352e-06 (rank : 22)	NC score	0.414452 (rank : 15)
Query Neighborhood Hits	142	Target Neighborhood Hits	58	Shared Neighborhood Hits	33
SwissProt Accessions	O15303	Gene names	GRM6, GPRC1F, MGLUR6
Domain Architecture
Description	Metabotropic glutamate receptor 6 precursor (mGluR6).

TS1R1_MOUSE
θ value	6.43352e-06 (rank : 23)	NC score	0.411575 (rank : 18)
Query Neighborhood Hits	142	Target Neighborhood Hits	57	Shared Neighborhood Hits	30
SwissProt Accessions	Q99PG6, Q6NS58, Q923J9, Q925I5, Q99PG5	Gene names	Tas1r1, Gpr70, T1r1, Tr1
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 1 precursor (G-protein coupled receptor 70).

ANPRC_HUMAN
θ value	1.09739e-05 (rank : 24)	NC score	0.337098 (rank : 33)
Query Neighborhood Hits	142	Target Neighborhood Hits	27	Shared Neighborhood Hits	20
SwissProt Accessions	P17342	Gene names	NPR3, ANPRC
Domain Architecture
Description	Atrial natriuretic peptide clearance receptor precursor (ANP-C) (ANPRC) (NPR-C) (Atrial natriuretic peptide C-type receptor).

ANPRC_MOUSE
θ value	1.09739e-05 (rank : 25)	NC score	0.343154 (rank : 32)
Query Neighborhood Hits	142	Target Neighborhood Hits	27	Shared Neighborhood Hits	21
SwissProt Accessions	P70180, P97804, Q9R025, Q9R027, Q9R028	Gene names	Npr3
Domain Architecture
Description	Atrial natriuretic peptide clearance receptor precursor (ANP-C) (ANPRC) (NPR-C) (Atrial natriuretic peptide C-type receptor) (EF-2).

CASR_MOUSE
θ value	1.09739e-05 (rank : 26)	NC score	0.411286 (rank : 19)
Query Neighborhood Hits	142	Target Neighborhood Hits	72	Shared Neighborhood Hits	29
SwissProt Accessions	Q9QY96, O08968, O88519, Q9QY95, Q9QZU8, Q9R1D6, Q9R1Y2	Gene names	Casr, Gprc2a
Domain Architecture
Description	Extracellular calcium-sensing receptor precursor (CaSR) (Parathyroid Cell calcium-sensing receptor).

LYAM2_MOUSE
θ value	1.09739e-05 (rank : 27)	NC score	0.266742 (rank : 58)
Query Neighborhood Hits	142	Target Neighborhood Hits	420	Shared Neighborhood Hits	49
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

MGR1_HUMAN
θ value	1.09739e-05 (rank : 28)	NC score	0.409002 (rank : 21)
Query Neighborhood Hits	142	Target Neighborhood Hits	85	Shared Neighborhood Hits	32
SwissProt Accessions	Q13255, Q13256, Q14757, Q14758, Q5VTF7, Q5VTF8, Q9NU10, Q9UGS9, Q9UGT0	Gene names	GRM1, GPRC1A, MGLUR1
Domain Architecture
Description	Metabotropic glutamate receptor 1 precursor (mGluR1).

TS1R3_MOUSE
θ value	1.09739e-05 (rank : 29)	NC score	0.426901 (rank : 9)
Query Neighborhood Hits	142	Target Neighborhood Hits	49	Shared Neighborhood Hits	32
SwissProt Accessions	Q925D8, Q91VA4, Q923K0, Q925A4, Q925D9	Gene names	Tas1r3, Sac, T1r3, Tr3
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 3 precursor (Sweet taste receptor T1R3) (Saccharin preference protein).

GPC6A_MOUSE
θ value	1.43324e-05 (rank : 30)	NC score	0.408472 (rank : 23)
Query Neighborhood Hits	142	Target Neighborhood Hits	57	Shared Neighborhood Hits	28
SwissProt Accessions	Q8K4Z6, Q5DK51, Q5DK52	Gene names	Gprc6a
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor family C group 6 member A precursor.

MGR1_MOUSE
θ value	1.43324e-05 (rank : 31)	NC score	0.408627 (rank : 22)
Query Neighborhood Hits	142	Target Neighborhood Hits	90	Shared Neighborhood Hits	33
SwissProt Accessions	P97772, Q6AXG4, Q9EPV6	Gene names	Grm1, Gprc1a, Mglur1
Domain Architecture
Description	Metabotropic glutamate receptor 1 precursor (mGluR1).

CR1_HUMAN
θ value	3.19293e-05 (rank : 32)	NC score	0.328548 (rank : 34)
Query Neighborhood Hits	142	Target Neighborhood Hits	108	Shared Neighborhood Hits	48
SwissProt Accessions	P17927, Q16745, Q9UQV2	Gene names	CR1, C3BR
Domain Architecture
Description	Complement receptor type 1 precursor (C3b/C4b receptor) (CD35 antigen).

MGR6_MOUSE
θ value	3.19293e-05 (rank : 33)	NC score	0.412963 (rank : 17)
Query Neighborhood Hits	142	Target Neighborhood Hits	56	Shared Neighborhood Hits	34
SwissProt Accessions	Q5NCH9	Gene names	Grm6, Gprc1f, Mglur6
Domain Architecture	No domain graphic available
Description	Metabotropic glutamate receptor 6 precursor (mGluR6).

MGR3_MOUSE
θ value	7.1131e-05 (rank : 34)	NC score	0.401067 (rank : 26)
Query Neighborhood Hits	142	Target Neighborhood Hits	54	Shared Neighborhood Hits	31
SwissProt Accessions	Q9QYS2	Gene names	Grm3, Gprc1c, Mglur3
Domain Architecture
Description	Metabotropic glutamate receptor 3 precursor (mGluR3).

LYAM3_MOUSE
θ value	9.29e-05 (rank : 35)	NC score	0.269442 (rank : 56)
Query Neighborhood Hits	142	Target Neighborhood Hits	390	Shared Neighborhood Hits	48
SwissProt Accessions	Q01102	Gene names	Selp, Grmp
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

TS1R2_MOUSE
θ value	9.29e-05 (rank : 36)	NC score	0.414671 (rank : 14)
Query Neighborhood Hits	142	Target Neighborhood Hits	69	Shared Neighborhood Hits	32
SwissProt Accessions	Q925I4, Q923J8	Gene names	Tas1r2, Gpr71, T1r2, Tr2
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 2 precursor (G-protein coupled receptor 71) (Sweet taste receptor T1R2).

CSMD2_HUMAN
θ value	0.000121331 (rank : 37)	NC score	0.252574 (rank : 63)
Query Neighborhood Hits	142	Target Neighborhood Hits	188	Shared Neighborhood Hits	48
SwissProt Accessions	Q7Z408, Q5VT59, Q8N963, Q96Q03, Q9H4V7, Q9H4V8, Q9H4V9, Q9H4W0, Q9H4W1, Q9H4W2, Q9H4W3, Q9H4W4, Q9HCY5, Q9HCY6, Q9HCY7	Gene names	CSMD2, KIAA1884
Domain Architecture
Description	CUB and sushi domain-containing protein 2 (CUB and sushi multiple domains protein 2).

MGR5_HUMAN
θ value	0.000158464 (rank : 38)	NC score	0.410516 (rank : 20)
Query Neighborhood Hits	142	Target Neighborhood Hits	72	Shared Neighborhood Hits	36
SwissProt Accessions	P41594	Gene names	GRM5, GPRC1E, MGLUR5
Domain Architecture
Description	Metabotropic glutamate receptor 5 precursor (mGluR5).

TS1R2_HUMAN
θ value	0.00020696 (rank : 39)	NC score	0.407079 (rank : 24)
Query Neighborhood Hits	142	Target Neighborhood Hits	48	Shared Neighborhood Hits	30
SwissProt Accessions	Q8TE23, Q5TZ19	Gene names	TAS1R2, GPR71, T1R2, TR2
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 2 precursor (G-protein coupled receptor 71) (Sweet taste receptor T1R2).

CFAH_HUMAN
θ value	0.000270298 (rank : 40)	NC score	0.304511 (rank : 43)
Query Neighborhood Hits	142	Target Neighborhood Hits	101	Shared Neighborhood Hits	48
SwissProt Accessions	P08603, P78435, Q14570, Q38G77, Q5TFM3, Q8N708, Q9NU86	Gene names	CFH, HF, HF1
Domain Architecture
Description	Complement factor H precursor (H factor 1).

FHR1_HUMAN
θ value	0.000270298 (rank : 41)	NC score	0.292516 (rank : 49)
Query Neighborhood Hits	142	Target Neighborhood Hits	80	Shared Neighborhood Hits	47
SwissProt Accessions	Q03591, Q9UJ17	Gene names	CFHL1, CFHL, FHR1, HFL1
Domain Architecture
Description	Complement factor H-related protein 1 precursor (FHR-1) (H factor-like protein 1) (H-factor-like 1) (H36).

GPC6A_HUMAN
θ value	0.000270298 (rank : 42)	NC score	0.402170 (rank : 25)
Query Neighborhood Hits	142	Target Neighborhood Hits	53	Shared Neighborhood Hits	28
SwissProt Accessions	Q5T6X5, Q6JK43, Q6JK44, Q8NGU8, Q8NHZ9, Q8TDT6	Gene names	GPRC6A, GPCR33
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor family C group 6 member A precursor (hGPRC6A) (G-protein coupled receptor 33) (hGPCR33).

CSMD1_MOUSE
θ value	0.00035302 (rank : 43)	NC score	0.252453 (rank : 64)
Query Neighborhood Hits	142	Target Neighborhood Hits	193	Shared Neighborhood Hits	48
SwissProt Accessions	Q923L3, Q8BUV1, Q8BYQ3	Gene names	Csmd1
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

LYAM3_HUMAN
θ value	0.00035302 (rank : 44)	NC score	0.269600 (rank : 55)
Query Neighborhood Hits	142	Target Neighborhood Hits	378	Shared Neighborhood Hits	48
SwissProt Accessions	P16109, Q8IVD1	Gene names	SELP, GMRP
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

DAF1_MOUSE
θ value	0.000602161 (rank : 45)	NC score	0.310954 (rank : 40)
Query Neighborhood Hits	142	Target Neighborhood Hits	204	Shared Neighborhood Hits	49
SwissProt Accessions	Q61475, P97732, Q61397	Gene names	Cd55a, Daf1
Domain Architecture
Description	Complement decay-accelerating factor, GPI-anchored precursor (DAF-GPI) (CD55 antigen).

MGR2_HUMAN
θ value	0.000786445 (rank : 46)	NC score	0.398100 (rank : 27)
Query Neighborhood Hits	142	Target Neighborhood Hits	56	Shared Neighborhood Hits	33
SwissProt Accessions	Q14416, Q52MC6, Q9H3N6	Gene names	GRM2, GPRC1B, MGLUR2
Domain Architecture
Description	Metabotropic glutamate receptor 2 precursor (mGluR2).

MGR3_HUMAN
θ value	0.000786445 (rank : 47)	NC score	0.395505 (rank : 28)
Query Neighborhood Hits	142	Target Neighborhood Hits	58	Shared Neighborhood Hits	31
SwissProt Accessions	Q14832, Q75MV4, Q75N17, Q86YG6, Q8TBH9	Gene names	GRM3, GPRC1C, MGLUR3
Domain Architecture
Description	Metabotropic glutamate receptor 3 precursor (mGluR3).

CR2_HUMAN
θ value	0.00102713 (rank : 48)	NC score	0.317294 (rank : 38)
Query Neighborhood Hits	142	Target Neighborhood Hits	89	Shared Neighborhood Hits	48
SwissProt Accessions	P20023, Q13866, Q14212	Gene names	CR2, C3DR
Domain Architecture
Description	Complement receptor type 2 precursor (Cr2) (Complement C3d receptor) (Epstein-Barr virus receptor) (EBV receptor) (CD21 antigen).

F13B_MOUSE
θ value	0.00102713 (rank : 49)	NC score	0.306724 (rank : 41)
Query Neighborhood Hits	142	Target Neighborhood Hits	93	Shared Neighborhood Hits	48
SwissProt Accessions	Q07968	Gene names	F13b, Cf13b
Domain Architecture
Description	Coagulation factor XIII B chain precursor (Protein-glutamine gamma- glutamyltransferase B chain) (Transglutaminase B chain).

CR2_MOUSE
θ value	0.00134147 (rank : 50)	NC score	0.317675 (rank : 37)
Query Neighborhood Hits	142	Target Neighborhood Hits	101	Shared Neighborhood Hits	48
SwissProt Accessions	P19070	Gene names	Cr2
Domain Architecture
Description	Complement receptor type 2 precursor (Cr2) (Complement C3d receptor) (CD21 antigen).

CRRY_MOUSE
θ value	0.00298849 (rank : 51)	NC score	0.323227 (rank : 36)
Query Neighborhood Hits	142	Target Neighborhood Hits	84	Shared Neighborhood Hits	49
SwissProt Accessions	Q64735, Q3TV30, Q58E68, Q61447, Q61449, Q8CF59, Q8K328	Gene names	Crry, Cry
Domain Architecture	No domain graphic available
Description	Complement regulatory protein Crry precursor (Protein p65).

LYAM2_HUMAN
θ value	0.00298849 (rank : 52)	NC score	0.253976 (rank : 62)
Query Neighborhood Hits	142	Target Neighborhood Hits	394	Shared Neighborhood Hits	48
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

SUSD2_HUMAN
θ value	0.00298849 (rank : 53)	NC score	0.238124 (rank : 68)
Query Neighborhood Hits	142	Target Neighborhood Hits	99	Shared Neighborhood Hits	48
SwissProt Accessions	Q9UGT4, Q9H5Y6	Gene names	SUSD2
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 2 precursor.

ZP3R_MOUSE
θ value	0.00298849 (rank : 54)	NC score	0.312720 (rank : 39)
Query Neighborhood Hits	142	Target Neighborhood Hits	81	Shared Neighborhood Hits	48
SwissProt Accessions	Q60736	Gene names	Zp3r, Sp56
Domain Architecture
Description	Zona pellucida sperm-binding protein 3 receptor precursor (Sperm fertilization protein 56) (sp56).

FHR5_HUMAN
θ value	0.00390308 (rank : 55)	NC score	0.293859 (rank : 48)
Query Neighborhood Hits	142	Target Neighborhood Hits	77	Shared Neighborhood Hits	46
SwissProt Accessions	Q9BXR6	Gene names	CFHL5, FHR5
Domain Architecture
Description	Complement factor H-related protein 5 precursor (FHR-5).

GRIA2_HUMAN
θ value	0.00665767 (rank : 56)	NC score	0.089487 (rank : 97)
Query Neighborhood Hits	142	Target Neighborhood Hits	47	Shared Neighborhood Hits	15
SwissProt Accessions	P42262, Q96FP6	Gene names	GRIA2, GLUR2
Domain Architecture
Description	Glutamate receptor 2 precursor (GluR-2) (GluR-B) (GluR-K2) (Glutamate receptor ionotropic, AMPA 2) (AMPA-selective glutamate receptor 2).

GRIA2_MOUSE
θ value	0.00665767 (rank : 57)	NC score	0.089522 (rank : 96)
Query Neighborhood Hits	142	Target Neighborhood Hits	47	Shared Neighborhood Hits	15
SwissProt Accessions	P23819, Q61604, Q61605, Q8BG69, Q8BXU3, Q9D6D3	Gene names	Gria2, Glur2
Domain Architecture
Description	Glutamate receptor 2 precursor (GluR-2) (GluR-B) (GluR-K2) (Glutamate receptor ionotropic, AMPA 2) (AMPA-selective glutamate receptor 2).

SUSD2_MOUSE
θ value	0.00869519 (rank : 58)	NC score	0.233876 (rank : 71)
Query Neighborhood Hits	142	Target Neighborhood Hits	104	Shared Neighborhood Hits	48
SwissProt Accessions	Q9DBX3, Q8BY19, Q8BYN0, Q8BYZ3, Q8BYZ9, Q8BZQ4, Q8C179	Gene names	Susd2
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 2 precursor.

C4BB_HUMAN
θ value	0.0148317 (rank : 59)	NC score	0.324147 (rank : 35)
Query Neighborhood Hits	142	Target Neighborhood Hits	77	Shared Neighborhood Hits	48
SwissProt Accessions	P20851	Gene names	C4BPB
Domain Architecture
Description	C4b-binding protein beta chain precursor.

MCP_MOUSE
θ value	0.0148317 (rank : 60)	NC score	0.306280 (rank : 42)
Query Neighborhood Hits	142	Target Neighborhood Hits	79	Shared Neighborhood Hits	48
SwissProt Accessions	O88174, Q9R0R9	Gene names	Cd46, Mcp
Domain Architecture	No domain graphic available
Description	Membrane cofactor protein precursor (CD46 antigen).

DAF2_MOUSE
θ value	0.0252991 (rank : 61)	NC score	0.299724 (rank : 46)
Query Neighborhood Hits	142	Target Neighborhood Hits	114	Shared Neighborhood Hits	48
SwissProt Accessions	Q61476	Gene names	Cd55b, Daf2
Domain Architecture
Description	Complement decay-accelerating factor transmembrane isoform precursor (DAF-TM) (CD55 antigen).

GRIA1_HUMAN
θ value	0.0252991 (rank : 62)	NC score	0.086102 (rank : 99)
Query Neighborhood Hits	142	Target Neighborhood Hits	45	Shared Neighborhood Hits	15
SwissProt Accessions	P42261	Gene names	GRIA1, GLUH1, GLUR1
Domain Architecture
Description	Glutamate receptor 1 precursor (GluR-1) (GluR-A) (GluR-K1) (Glutamate receptor ionotropic, AMPA 1) (AMPA-selective glutamate receptor 1).

GRIA1_MOUSE
θ value	0.0252991 (rank : 63)	NC score	0.086358 (rank : 98)
Query Neighborhood Hits	142	Target Neighborhood Hits	46	Shared Neighborhood Hits	16
SwissProt Accessions	P23818	Gene names	Gria1, Glur1
Domain Architecture
Description	Glutamate receptor 1 precursor (GluR-1) (GluR-A) (GluR-K1) (Glutamate receptor ionotropic, AMPA 1) (AMPA-selective glutamate receptor 1).

FHR3_HUMAN
θ value	0.0330416 (rank : 64)	NC score	0.260557 (rank : 61)
Query Neighborhood Hits	142	Target Neighborhood Hits	74	Shared Neighborhood Hits	45
SwissProt Accessions	Q02985, Q9UJ16	Gene names	CFHL3, FHR3
Domain Architecture
Description	Complement factor H-related protein 3 precursor (FHR-3) (H factor-like protein 3) (DOWN16).

CO6_HUMAN
θ value	0.0431538 (rank : 65)	NC score	0.132321 (rank : 82)
Query Neighborhood Hits	142	Target Neighborhood Hits	331	Shared Neighborhood Hits	45
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

CFAH_MOUSE
θ value	0.0563607 (rank : 66)	NC score	0.287860 (rank : 52)
Query Neighborhood Hits	142	Target Neighborhood Hits	112	Shared Neighborhood Hits	48
SwissProt Accessions	P06909	Gene names	Cfh, Hf1
Domain Architecture
Description	Complement factor H precursor (Protein beta-1-H).

CO2_HUMAN
θ value	0.0563607 (rank : 67)	NC score	0.165973 (rank : 74)
Query Neighborhood Hits	142	Target Neighborhood Hits	258	Shared Neighborhood Hits	47
SwissProt Accessions	P06681, O19694, Q13904	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

F13B_HUMAN
θ value	0.0563607 (rank : 68)	NC score	0.292252 (rank : 50)
Query Neighborhood Hits	142	Target Neighborhood Hits	84	Shared Neighborhood Hits	47
SwissProt Accessions	P05160	Gene names	F13B
Domain Architecture
Description	Coagulation factor XIII B chain precursor (Protein-glutamine gamma- glutamyltransferase B chain) (Transglutaminase B chain) (Fibrin- stabilizing factor B subunit).

CO2_MOUSE
θ value	0.0736092 (rank : 69)	NC score	0.143267 (rank : 80)
Query Neighborhood Hits	142	Target Neighborhood Hits	250	Shared Neighborhood Hits	46
SwissProt Accessions	P21180	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

SEZ6L_HUMAN
θ value	0.0736092 (rank : 70)	NC score	0.237703 (rank : 69)
Query Neighborhood Hits	142	Target Neighborhood Hits	289	Shared Neighborhood Hits	49
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.

SUSD4_HUMAN
θ value	0.0736092 (rank : 71)	NC score	0.272506 (rank : 54)
Query Neighborhood Hits	142	Target Neighborhood Hits	88	Shared Neighborhood Hits	48
SwissProt Accessions	Q5VX71, Q6UX62, Q9BSR0, Q9NWG0	Gene names	SUSD4
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 4 precursor.

C4BP_MOUSE
θ value	0.0961366 (rank : 72)	NC score	0.302951 (rank : 44)
Query Neighborhood Hits	142	Target Neighborhood Hits	91	Shared Neighborhood Hits	48
SwissProt Accessions	P08607	Gene names	C4bpa, C4bp
Domain Architecture
Description	C4b-binding protein precursor (C4bp).

MCP_HUMAN
θ value	0.0961366 (rank : 73)	NC score	0.301708 (rank : 45)
Query Neighborhood Hits	142	Target Neighborhood Hits	82	Shared Neighborhood Hits	48
SwissProt Accessions	P15529, Q15429, Q53GV9, Q5HY94, Q5VWS6, Q5VWS7, Q5VWS8, Q5VWS9, Q5VWT0, Q5VWT1, Q5VWT2, Q6N0A1, Q7Z3R5, Q9NNW2, Q9NNW3, Q9NNW4	Gene names	CD46, MCP
Domain Architecture
Description	Membrane cofactor protein precursor (Trophoblast leukocyte common antigen) (TLX) (CD46 antigen).

APOH_HUMAN
θ value	0.125558 (rank : 74)	NC score	0.292136 (rank : 51)
Query Neighborhood Hits	142	Target Neighborhood Hits	75	Shared Neighborhood Hits	48
SwissProt Accessions	P02749, Q9UCN7	Gene names	APOH, B2G1
Domain Architecture
Description	Beta-2-glycoprotein 1 precursor (Beta-2-glycoprotein I) (Apolipoprotein H) (Apo-H) (B2GPI) (Beta(2)GPI) (Activated protein C- binding protein) (APC inhibitor) (Anticardiolipin cofactor).

LYAM1_MOUSE
θ value	0.125558 (rank : 75)	NC score	0.196092 (rank : 72)
Query Neighborhood Hits	142	Target Neighborhood Hits	332	Shared Neighborhood Hits	41
SwissProt Accessions	P18337	Gene names	Sell, Lnhr, Ly-22
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Lymphocyte antigen 22) (Ly-22) (Lymphocyte surface MEL-14 antigen) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

NMDE4_HUMAN
θ value	0.163984 (rank : 76)	NC score	0.072748 (rank : 108)
Query Neighborhood Hits	142	Target Neighborhood Hits	133	Shared Neighborhood Hits	20
SwissProt Accessions	O15399	Gene names	GRIN2D
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 4 precursor (N-methyl D- aspartate receptor subtype 2D) (NR2D) (NMDAR2D) (EB11).

C4BP_HUMAN
θ value	0.21417 (rank : 77)	NC score	0.295637 (rank : 47)
Query Neighborhood Hits	142	Target Neighborhood Hits	92	Shared Neighborhood Hits	48
SwissProt Accessions	P04003	Gene names	C4BPA, C4BP
Domain Architecture
Description	C4b-binding protein alpha chain precursor (C4bp) (Proline-rich protein) (PRP).

CFAB_HUMAN
θ value	0.21417 (rank : 78)	NC score	0.161694 (rank : 75)
Query Neighborhood Hits	142	Target Neighborhood Hits	251	Shared Neighborhood Hits	48
SwissProt Accessions	P00751, O15006, Q29944, Q96HX6, Q9BTF5, Q9BX92	Gene names	CFB, BF
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) (Properdin factor B) (Glycine-rich beta glycoprotein) (GBG) (PBF2) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

GUC2F_HUMAN
θ value	0.21417 (rank : 79)	NC score	0.096785 (rank : 93)
Query Neighborhood Hits	142	Target Neighborhood Hits	740	Shared Neighborhood Hits	27
SwissProt Accessions	P51841, Q9UJF1	Gene names	GUCY2F, GUC2F, RETGC2
Domain Architecture
Description	Retinal guanylyl cyclase 2 precursor (EC 4.6.1.2) (Guanylate cyclase 2F, retinal) (RETGC-2) (Rod outer segment membrane guanylate cyclase 2) (ROS-GC2) (Guanylate cyclase F) (GC-F).

FHR4_HUMAN
θ value	0.279714 (rank : 80)	NC score	0.246503 (rank : 65)
Query Neighborhood Hits	142	Target Neighborhood Hits	75	Shared Neighborhood Hits	44
SwissProt Accessions	Q92496, Q9UJY6	Gene names	CFHL4, FHR4
Domain Architecture
Description	Complement factor H-related protein 4 precursor (FHR-4).

NMDE4_MOUSE
θ value	0.279714 (rank : 81)	NC score	0.070125 (rank : 115)
Query Neighborhood Hits	142	Target Neighborhood Hits	158	Shared Neighborhood Hits	19
SwissProt Accessions	Q03391	Gene names	Grin2d
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 4 precursor (N-methyl D- aspartate receptor subtype 2D) (NR2D) (NMDAR2D).

SUSD4_MOUSE
θ value	0.279714 (rank : 82)	NC score	0.266962 (rank : 57)
Query Neighborhood Hits	142	Target Neighborhood Hits	122	Shared Neighborhood Hits	48
SwissProt Accessions	Q8BH32, Q8VC43	Gene names	Susd4
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 4 precursor.

CFAB_MOUSE
θ value	0.813845 (rank : 83)	NC score	0.155331 (rank : 76)
Query Neighborhood Hits	142	Target Neighborhood Hits	262	Shared Neighborhood Hits	47
SwissProt Accessions	P04186	Gene names	Cfb, Bf, H2-Bf
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

FHR2_HUMAN
θ value	0.813845 (rank : 84)	NC score	0.244172 (rank : 66)
Query Neighborhood Hits	142	Target Neighborhood Hits	63	Shared Neighborhood Hits	45
SwissProt Accessions	P36980, Q14310	Gene names	CFHL2, FHR2, HFL3
Domain Architecture
Description	Complement factor H-related protein 2 precursor (FHR-2) (H factor-like protein 2) (H factor-like 3) (DDESK59).

ATF3_HUMAN
θ value	1.06291 (rank : 85)	NC score	0.054351 (rank : 134)
Query Neighborhood Hits	142	Target Neighborhood Hits	120	Shared Neighborhood Hits	8
SwissProt Accessions	P18847	Gene names	ATF3
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-3 (Activating transcription factor 3).

ATF3_MOUSE
θ value	1.06291 (rank : 86)	NC score	0.054136 (rank : 135)
Query Neighborhood Hits	142	Target Neighborhood Hits	120	Shared Neighborhood Hits	7
SwissProt Accessions	Q60765	Gene names	Atf3
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-3 (Activating transcription factor 3) (Transcription factor LRG-21).

CP250_HUMAN
θ value	1.06291 (rank : 87)	NC score	0.013798 (rank : 159)
Query Neighborhood Hits	142	Target Neighborhood Hits	1805	Shared Neighborhood Hits	31
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

GP158_HUMAN
θ value	1.06291 (rank : 88)	NC score	0.116436 (rank : 90)
Query Neighborhood Hits	142	Target Neighborhood Hits	221	Shared Neighborhood Hits	20
SwissProt Accessions	Q5T848, Q6QR81, Q9ULT3	Gene names	GPR158, KIAA1136
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 158 precursor.

GRIK4_HUMAN
θ value	1.06291 (rank : 89)	NC score	0.071071 (rank : 112)
Query Neighborhood Hits	142	Target Neighborhood Hits	42	Shared Neighborhood Hits	19
SwissProt Accessions	Q16099	Gene names	GRIK4, GRIK
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 4 precursor (Glutamate receptor KA-1) (KA1) (Excitatory amino acid receptor 1) (EAA1).

EVPL_HUMAN
θ value	1.38821 (rank : 90)	NC score	0.019705 (rank : 149)
Query Neighborhood Hits	142	Target Neighborhood Hits	895	Shared Neighborhood Hits	26
SwissProt Accessions	Q92817	Gene names	EVPL
Domain Architecture
Description	Envoplakin (210 kDa paraneoplastic pemphigus antigen) (p210) (210 kDa cornified envelope precursor protein).

GRIA3_MOUSE
θ value	1.38821 (rank : 91)	NC score	0.074603 (rank : 105)
Query Neighborhood Hits	142	Target Neighborhood Hits	39	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Z2W9, Q5DTJ0	Gene names	Gria3, Glur3, Kiaa4184
Domain Architecture	No domain graphic available
Description	Glutamate receptor 3 precursor (GluR-3) (GluR-C) (GluR-K3) (Glutamate receptor ionotropic, AMPA 3) (AMPA-selective glutamate receptor 3).

LYAM1_HUMAN
θ value	1.38821 (rank : 92)	NC score	0.189960 (rank : 73)
Query Neighborhood Hits	142	Target Neighborhood Hits	315	Shared Neighborhood Hits	44
SwissProt Accessions	P14151, P15023	Gene names	SELL, LNHR, LYAM1
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Leukocyte surface antigen Leu-8) (TQ1) (gp90-MEL) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

SRPX_MOUSE
θ value	1.38821 (rank : 93)	NC score	0.243520 (rank : 67)
Query Neighborhood Hits	142	Target Neighborhood Hits	75	Shared Neighborhood Hits	47
SwissProt Accessions	Q9R0M3, Q9R0M2	Gene names	Srpx
Domain Architecture	No domain graphic available
Description	Sushi-repeat-containing protein SRPX precursor (DRS protein).

CCD46_HUMAN
θ value	1.81305 (rank : 94)	NC score	0.015412 (rank : 156)
Query Neighborhood Hits	142	Target Neighborhood Hits	1430	Shared Neighborhood Hits	32
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

GRID2_HUMAN
θ value	1.81305 (rank : 95)	NC score	0.067449 (rank : 119)
Query Neighborhood Hits	142	Target Neighborhood Hits	48	Shared Neighborhood Hits	16
SwissProt Accessions	O43424	Gene names	GRID2, GLURD2
Domain Architecture
Description	Glutamate receptor delta-2 subunit precursor (GluR delta-2).

PAPOB_MOUSE
θ value	1.81305 (rank : 96)	NC score	0.035523 (rank : 143)
Query Neighborhood Hits	142	Target Neighborhood Hits	25	Shared Neighborhood Hits	6
SwissProt Accessions	Q9WVP6, Q9R1R3	Gene names	Papolb, Papt, Tpap
Domain Architecture
Description	Poly(A) polymerase beta (EC 2.7.7.19) (PAP beta) (Polynucleotide adenylyltransferase beta) (Testis-specific poly(A) polymerase).

SRPX_HUMAN
θ value	1.81305 (rank : 97)	NC score	0.237504 (rank : 70)
Query Neighborhood Hits	142	Target Neighborhood Hits	69	Shared Neighborhood Hits	47
SwissProt Accessions	P78539, Q99652, Q99913	Gene names	SRPX, ETX1
Domain Architecture
Description	Sushi repeat-containing protein SRPX precursor.

ATCAY_MOUSE
θ value	2.36792 (rank : 98)	NC score	0.021450 (rank : 148)
Query Neighborhood Hits	142	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BHE3, Q3TR94	Gene names	Atcay
Domain Architecture
Description	Caytaxin.

GRIK4_MOUSE
θ value	2.36792 (rank : 99)	NC score	0.068348 (rank : 118)
Query Neighborhood Hits	142	Target Neighborhood Hits	41	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BMF5	Gene names	Grik4
Domain Architecture	No domain graphic available
Description	Glutamate receptor, ionotropic kainate 4 precursor.

K1C14_MOUSE
θ value	2.36792 (rank : 100)	NC score	0.013611 (rank : 160)
Query Neighborhood Hits	142	Target Neighborhood Hits	501	Shared Neighborhood Hits	27
SwissProt Accessions	Q61781, Q91VQ4	Gene names	Krt14, Krt1-14
Domain Architecture
Description	Keratin, type I cytoskeletal 14 (Cytokeratin-14) (CK-14) (Keratin-14) (K14).

APOH_MOUSE
θ value	3.0926 (rank : 101)	NC score	0.275144 (rank : 53)
Query Neighborhood Hits	142	Target Neighborhood Hits	74	Shared Neighborhood Hits	48
SwissProt Accessions	Q01339	Gene names	Apoh, B2gp1
Domain Architecture
Description	Beta-2-glycoprotein 1 precursor (Beta-2-glycoprotein I) (Apolipoprotein H) (Apo-H) (B2GPI) (Beta(2)GPI) (Activated protein C- binding protein) (APC inhibitor).

GRIA3_HUMAN
θ value	3.0926 (rank : 102)	NC score	0.072167 (rank : 111)
Query Neighborhood Hits	142	Target Neighborhood Hits	40	Shared Neighborhood Hits	16
SwissProt Accessions	P42263, Q4VXD5, Q4VXD6, Q9HDA0, Q9HDA1, Q9HDA2	Gene names	GRIA3, GLUR3, GLURC
Domain Architecture
Description	Glutamate receptor 3 precursor (GluR-3) (GluR-C) (GluR-K3) (Glutamate receptor ionotropic, AMPA 3) (AMPA-selective glutamate receptor 3).

GRID2_MOUSE
θ value	3.0926 (rank : 103)	NC score	0.065810 (rank : 122)
Query Neighborhood Hits	142	Target Neighborhood Hits	44	Shared Neighborhood Hits	16
SwissProt Accessions	Q61625	Gene names	Grid2
Domain Architecture
Description	Glutamate receptor delta-2 subunit precursor (GluR delta-2).

HAP1_HUMAN
θ value	3.0926 (rank : 104)	NC score	0.026558 (rank : 147)
Query Neighborhood Hits	142	Target Neighborhood Hits	606	Shared Neighborhood Hits	26
SwissProt Accessions	P54257, O75358, Q9H4G3, Q9HA98, Q9NY90	Gene names	HAP1, HLP1
Domain Architecture
Description	Huntingtin-associated protein 1 (HAP-1) (Neuroan 1).

HEM0_HUMAN
θ value	3.0926 (rank : 105)	NC score	0.019035 (rank : 151)
Query Neighborhood Hits	142	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	P22557, Q13735	Gene names	ALAS2, ALASE, ASB
Domain Architecture
Description	5-aminolevulinate synthase, erythroid-specific, mitochondrial precursor (EC 2.3.1.37) (5-aminolevulinic acid synthase) (Delta- aminolevulinate synthase) (Delta-ALA synthetase) (ALAS-E).

HOME2_MOUSE
θ value	3.0926 (rank : 106)	NC score	0.016151 (rank : 154)
Query Neighborhood Hits	142	Target Neighborhood Hits	882	Shared Neighborhood Hits	30
SwissProt Accessions	Q9QWW1, O89025, Q9Z0E4	Gene names	Homer2, Vesl2
Domain Architecture
Description	Homer protein homolog 2 (Homer-2) (Cupidin) (VASP/Ena-related gene up- regulated during seizure and LTP 2) (Vesl-2).

K1H4_HUMAN
θ value	3.0926 (rank : 107)	NC score	0.011581 (rank : 168)
Query Neighborhood Hits	142	Target Neighborhood Hits	476	Shared Neighborhood Hits	22
SwissProt Accessions	O76011	Gene names	KRTHA4, HHA4, HKA4
Domain Architecture
Description	Keratin, type I cuticular Ha4 (Hair keratin, type I Ha4).

ROCK2_HUMAN
θ value	3.0926 (rank : 108)	NC score	0.007883 (rank : 179)
Query Neighborhood Hits	142	Target Neighborhood Hits	2073	Shared Neighborhood Hits	37
SwissProt Accessions	O75116, Q9UQN5	Gene names	ROCK2, KIAA0619
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2).

TPR_HUMAN
θ value	3.0926 (rank : 109)	NC score	0.012475 (rank : 165)
Query Neighborhood Hits	142	Target Neighborhood Hits	1921	Shared Neighborhood Hits	31
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

ANR26_MOUSE
θ value	4.03905 (rank : 110)	NC score	0.010250 (rank : 174)
Query Neighborhood Hits	142	Target Neighborhood Hits	1554	Shared Neighborhood Hits	33
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

CT2NL_HUMAN
θ value	4.03905 (rank : 111)	NC score	0.017260 (rank : 153)
Query Neighborhood Hits	142	Target Neighborhood Hits	1059	Shared Neighborhood Hits	26
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

ASPP1_MOUSE
θ value	5.27518 (rank : 112)	NC score	0.005403 (rank : 183)
Query Neighborhood Hits	142	Target Neighborhood Hits	1244	Shared Neighborhood Hits	25
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

CCD21_HUMAN
θ value	5.27518 (rank : 113)	NC score	0.013400 (rank : 161)
Query Neighborhood Hits	142	Target Neighborhood Hits	1228	Shared Neighborhood Hits	30
SwissProt Accessions	Q6P2H3, Q5VY68, Q5VY70, Q9H6Q1, Q9H828, Q9UF52	Gene names	CCDC21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

CT2NL_MOUSE
θ value	5.27518 (rank : 114)	NC score	0.019628 (rank : 150)
Query Neighborhood Hits	142	Target Neighborhood Hits	902	Shared Neighborhood Hits	25
SwissProt Accessions	Q99LJ0, Q6ZPR0, Q8BSV1	Gene names	Cttnbp2nl, Kiaa1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

GUC2G_MOUSE
θ value	5.27518 (rank : 115)	NC score	0.096647 (rank : 94)
Query Neighborhood Hits	142	Target Neighborhood Hits	644	Shared Neighborhood Hits	31
SwissProt Accessions	Q6TL19, Q8BWU7	Gene names	Gucy2g
Domain Architecture	No domain graphic available
Description	Guanylate cyclase 2G precursor (EC 4.6.1.2) (Guanylyl cyclase receptor G) (mGC-G).

KI13A_MOUSE
θ value	5.27518 (rank : 116)	NC score	0.006518 (rank : 182)
Query Neighborhood Hits	142	Target Neighborhood Hits	395	Shared Neighborhood Hits	21
SwissProt Accessions	Q9EQW7, O35062	Gene names	Kif13a
Domain Architecture
Description	Kinesin-like protein KIF13A.

MYH9_HUMAN
θ value	5.27518 (rank : 117)	NC score	0.013147 (rank : 163)
Query Neighborhood Hits	142	Target Neighborhood Hits	1762	Shared Neighborhood Hits	32
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

MYH9_MOUSE
θ value	5.27518 (rank : 118)	NC score	0.013158 (rank : 162)
Query Neighborhood Hits	142	Target Neighborhood Hits	1829	Shared Neighborhood Hits	33
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

PAPOA_HUMAN
θ value	5.27518 (rank : 119)	NC score	0.028922 (rank : 146)
Query Neighborhood Hits	142	Target Neighborhood Hits	75	Shared Neighborhood Hits	6
SwissProt Accessions	P51003, Q86SX4, Q86TV0, Q8IYF5, Q9BVU2	Gene names	PAPOLA, PAP
Domain Architecture	No domain graphic available
Description	Poly(A) polymerase alpha (EC 2.7.7.19) (PAP) (Polynucleotide adenylyltransferase alpha).

PAPOA_MOUSE
θ value	5.27518 (rank : 120)	NC score	0.030859 (rank : 144)
Query Neighborhood Hits	142	Target Neighborhood Hits	115	Shared Neighborhood Hits	8
SwissProt Accessions	Q61183, Q61208, Q61209, Q8K4X2	Gene names	Papola, Pap, Plap
Domain Architecture
Description	Poly(A) polymerase alpha (EC 2.7.7.19) (PAP) (Polynucleotide adenylyltransferase).

PAPOB_HUMAN
θ value	5.27518 (rank : 121)	NC score	0.029424 (rank : 145)
Query Neighborhood Hits	142	Target Neighborhood Hits	25	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NRJ5, Q8NE14	Gene names	PAPOLB, PAPT
Domain Architecture
Description	Poly(A) polymerase beta (EC 2.7.7.19) (PAP beta) (Polynucleotide adenylyltransferase beta) (Testis-specific poly(A) polymerase).

TRI63_HUMAN
θ value	5.27518 (rank : 122)	NC score	0.008644 (rank : 178)
Query Neighborhood Hits	142	Target Neighborhood Hits	298	Shared Neighborhood Hits	15
SwissProt Accessions	Q969Q1, Q5T2I1, Q96BD3, Q96KD9, Q9BYV4	Gene names	TRIM63, IRF, MURF1, RNF28, SMRZ
Domain Architecture
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (RING finger protein 28) (Striated muscle RING zinc finger protein) (Iris RING finger protein).

CALI_HUMAN
θ value	6.88961 (rank : 123)	NC score	0.007627 (rank : 180)
Query Neighborhood Hits	142	Target Neighborhood Hits	183	Shared Neighborhood Hits	4
SwissProt Accessions	Q13939, Q9BXG7	Gene names	CCIN
Domain Architecture
Description	Calicin.

GEMI5_MOUSE
θ value	6.88961 (rank : 124)	NC score	0.009118 (rank : 177)
Query Neighborhood Hits	142	Target Neighborhood Hits	424	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BX17	Gene names	Gemin5
Domain Architecture
Description	Gem-associated protein 5 (Gemin5).

HIP1_HUMAN
θ value	6.88961 (rank : 125)	NC score	0.012426 (rank : 166)
Query Neighborhood Hits	142	Target Neighborhood Hits	1016	Shared Neighborhood Hits	27
SwissProt Accessions	O00291, O00328, Q8TDL4	Gene names	HIP1
Domain Architecture
Description	Huntingtin-interacting protein 1 (HIP-I).

MYH2_HUMAN
θ value	6.88961 (rank : 126)	NC score	0.012618 (rank : 164)
Query Neighborhood Hits	142	Target Neighborhood Hits	1491	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UKX2, Q14322, Q16229	Gene names	MYH2, MYHSA2
Domain Architecture
Description	Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy chain IIa) (MyHC-IIa).

ROCK2_MOUSE
θ value	6.88961 (rank : 127)	NC score	0.006813 (rank : 181)
Query Neighborhood Hits	142	Target Neighborhood Hits	2072	Shared Neighborhood Hits	37
SwissProt Accessions	P70336, Q8BR64, Q8CBR0	Gene names	Rock2
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2).

RTN3_HUMAN
θ value	6.88961 (rank : 128)	NC score	0.017671 (rank : 152)
Query Neighborhood Hits	142	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	O95197, Q496K2, Q7RTM8	Gene names	RTN3, NSPL2
Domain Architecture
Description	Reticulon-3 (Neuroendocrine-specific protein-like 2) (NSP-like protein II) (NSPLII).

SAS10_MOUSE
θ value	6.88961 (rank : 129)	NC score	0.014455 (rank : 157)
Query Neighborhood Hits	142	Target Neighborhood Hits	81	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JI13, Q3UL95, Q8R5C6, Q9JJ12	Gene names	Crlz1, Crl1, Sas10
Domain Architecture	No domain graphic available
Description	Something about silencing protein 10 (Disrupter of silencing SAS10) (Charged amino acid-rich leucine zipper 1) (Crl-1).

TRAK1_HUMAN
θ value	6.88961 (rank : 130)	NC score	0.014031 (rank : 158)
Query Neighborhood Hits	142	Target Neighborhood Hits	660	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UPV9, Q96B69	Gene names	TRAK1, KIAA1042, OIP106
Domain Architecture	No domain graphic available
Description	Trafficking kinesin-binding protein 1 (106 kDa O-GlcNAc transferase- interacting protein).

CP135_MOUSE
θ value	8.99809 (rank : 131)	NC score	0.011431 (rank : 169)
Query Neighborhood Hits	142	Target Neighborhood Hits	1278	Shared Neighborhood Hits	29
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

K1C14_HUMAN
θ value	8.99809 (rank : 132)	NC score	0.011376 (rank : 170)
Query Neighborhood Hits	142	Target Neighborhood Hits	491	Shared Neighborhood Hits	25
SwissProt Accessions	P02533, Q14715, Q53XY3, Q9BUE3, Q9UBN2, Q9UBN3, Q9UCY4	Gene names	KRT14
Domain Architecture
Description	Keratin, type I cytoskeletal 14 (Cytokeratin-14) (CK-14) (Keratin-14) (K14).

K1C16_HUMAN
θ value	8.99809 (rank : 133)	NC score	0.009127 (rank : 176)
Query Neighborhood Hits	142	Target Neighborhood Hits	440	Shared Neighborhood Hits	23
SwissProt Accessions	P08779, P30654, Q16402, Q9UBG8	Gene names	KRT16, KRT16A
Domain Architecture
Description	Keratin, type I cytoskeletal 16 (Cytokeratin-16) (CK-16) (Keratin-16) (K16).

MASTL_HUMAN
θ value	8.99809 (rank : 134)	NC score	0.001241 (rank : 184)
Query Neighborhood Hits	142	Target Neighborhood Hits	894	Shared Neighborhood Hits	12
SwissProt Accessions	Q96GX5, Q5T8D5, Q5T8D7, Q8NCD6, Q96SJ5	Gene names	MASTL, THC2
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase-like (EC 2.7.11.1).

MYH10_HUMAN
θ value	8.99809 (rank : 135)	NC score	0.011122 (rank : 171)
Query Neighborhood Hits	142	Target Neighborhood Hits	1620	Shared Neighborhood Hits	31
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH10_MOUSE
θ value	8.99809 (rank : 136)	NC score	0.010999 (rank : 172)
Query Neighborhood Hits	142	Target Neighborhood Hits	1612	Shared Neighborhood Hits	31
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH1_HUMAN
θ value	8.99809 (rank : 137)	NC score	0.010975 (rank : 173)
Query Neighborhood Hits	142	Target Neighborhood Hits	1478	Shared Neighborhood Hits	31
SwissProt Accessions	P12882, Q9Y622	Gene names	MYH1
Domain Architecture
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1) (Myosin heavy chain IIx/d) (MyHC-IIx/d).

MYH1_MOUSE
θ value	8.99809 (rank : 138)	NC score	0.012074 (rank : 167)
Query Neighborhood Hits	142	Target Neighborhood Hits	1461	Shared Neighborhood Hits	32
SwissProt Accessions	Q5SX40	Gene names	Myh1
Domain Architecture	No domain graphic available
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1).

NMDE2_MOUSE
θ value	8.99809 (rank : 139)	NC score	0.058557 (rank : 126)
Query Neighborhood Hits	142	Target Neighborhood Hits	64	Shared Neighborhood Hits	19
SwissProt Accessions	Q01097, Q9DCB2	Gene names	Grin2b
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 2 precursor (N-methyl D- aspartate receptor subtype 2B) (NR2B) (NMDAR2B).

PCDBC_HUMAN
θ value	8.99809 (rank : 140)	NC score	0.000156 (rank : 185)
Query Neighborhood Hits	142	Target Neighborhood Hits	157	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y5F1	Gene names	PCDHB12
Domain Architecture
Description	Protocadherin beta 12 precursor (PCDH-beta12).

RTN3_MOUSE
θ value	8.99809 (rank : 141)	NC score	0.015492 (rank : 155)
Query Neighborhood Hits	142	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ES97	Gene names	Rtn3
Domain Architecture
Description	Reticulon-3.

TROAP_HUMAN
θ value	8.99809 (rank : 142)	NC score	0.010210 (rank : 175)
Query Neighborhood Hits	142	Target Neighborhood Hits	258	Shared Neighborhood Hits	3
SwissProt Accessions	Q12815	Gene names	TROAP
Domain Architecture	No domain graphic available
Description	Trophinin-associated protein (Tastin) (Trophinin-assisting protein).

ADCY9_HUMAN
θ value	θ > 10 (rank : 143)	NC score	0.051089 (rank : 140)
Query Neighborhood Hits	142	Target Neighborhood Hits	51	Shared Neighborhood Hits	6
SwissProt Accessions	O60503, O60273, Q4ZHT9, Q4ZIR5, Q9BWT4, Q9UGP2	Gene names	ADCY9, KIAA0520
Domain Architecture
Description	Adenylate cyclase type 9 (EC 4.6.1.1) (Adenylate cyclase type IX) (ATP pyrophosphate-lyase 9) (Adenylyl cyclase 9).

ADCY9_MOUSE
θ value	θ > 10 (rank : 144)	NC score	0.050969 (rank : 141)
Query Neighborhood Hits	142	Target Neighborhood Hits	46	Shared Neighborhood Hits	6
SwissProt Accessions	P51830, Q61279	Gene names	Adcy9
Domain Architecture
Description	Adenylate cyclase type 9 (EC 4.6.1.1) (Adenylate cyclase type IX) (ATP pyrophosphate-lyase 9) (Adenylyl cyclase 9) (Adenylyl cyclase type 10) (ACTP10).

CO7_HUMAN
θ value	θ > 10 (rank : 145)	NC score	0.119791 (rank : 88)
Query Neighborhood Hits	142	Target Neighborhood Hits	278	Shared Neighborhood Hits	43
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

GCYA2_HUMAN
θ value	θ > 10 (rank : 146)	NC score	0.074837 (rank : 104)
Query Neighborhood Hits	142	Target Neighborhood Hits	50	Shared Neighborhood Hits	6
SwissProt Accessions	P33402	Gene names	GUCY1A2, GUC1A2, GUCSA2
Domain Architecture
Description	Guanylate cyclase soluble subunit alpha-2 (EC 4.6.1.2) (GCS-alpha-2).

GCYA3_HUMAN
θ value	θ > 10 (rank : 147)	NC score	0.072505 (rank : 110)
Query Neighborhood Hits	142	Target Neighborhood Hits	36	Shared Neighborhood Hits	6
SwissProt Accessions	Q02108, O43843, Q8TAH3	Gene names	GUCY1A3, GUC1A3, GUCSA3, GUCY1A1
Domain Architecture
Description	Guanylate cyclase soluble subunit alpha-3 (EC 4.6.1.2) (GCS-alpha-3) (Soluble guanylate cyclase large subunit) (GCS-alpha-1).

GCYA3_MOUSE
θ value	θ > 10 (rank : 148)	NC score	0.072540 (rank : 109)
Query Neighborhood Hits	142	Target Neighborhood Hits	41	Shared Neighborhood Hits	6
SwissProt Accessions	Q9ERL9, Q9DBQ3	Gene names	Gucy1a3, Gucy1a1
Domain Architecture
Description	Guanylate cyclase soluble subunit alpha-3 (EC 4.6.1.2) (GCS-alpha-3) (Soluble guanylate cyclase large subunit) (GCS-alpha-1).

GCYB1_HUMAN
θ value	θ > 10 (rank : 149)	NC score	0.074052 (rank : 107)
Query Neighborhood Hits	142	Target Neighborhood Hits	41	Shared Neighborhood Hits	6
SwissProt Accessions	Q02153, Q86WY5	Gene names	GUCY1B3, GUC1B3, GUCSB3, GUCY1B1
Domain Architecture
Description	Guanylate cyclase soluble subunit beta-1 (EC 4.6.1.2) (GCS-beta-1) (Soluble guanylate cyclase small subunit) (GCS-beta-3).

GCYB1_MOUSE
θ value	θ > 10 (rank : 150)	NC score	0.074179 (rank : 106)
Query Neighborhood Hits	142	Target Neighborhood Hits	40	Shared Neighborhood Hits	6
SwissProt Accessions	O54865	Gene names	Gucy1b3
Domain Architecture	No domain graphic available
Description	Guanylate cyclase soluble subunit beta-1 (EC 4.6.1.2) (GCS-beta-1) (Soluble guanylate cyclase small subunit).

GCYB2_HUMAN
θ value	θ > 10 (rank : 151)	NC score	0.081117 (rank : 100)
Query Neighborhood Hits	142	Target Neighborhood Hits	61	Shared Neighborhood Hits	6
SwissProt Accessions	O75343, Q9NZ64	Gene names	GUCY1B2
Domain Architecture
Description	Guanylate cyclase soluble subunit beta-2 (EC 4.6.1.2) (GCS-beta-2).

GP158_MOUSE
θ value	θ > 10 (rank : 152)	NC score	0.094516 (rank : 95)
Query Neighborhood Hits	142	Target Neighborhood Hits	82	Shared Neighborhood Hits	17
SwissProt Accessions	Q8C419, Q8CHB0	Gene names	Gpr158, Kiaa1136
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 158 precursor.

GP179_HUMAN
θ value	θ > 10 (rank : 153)	NC score	0.079502 (rank : 103)
Query Neighborhood Hits	142	Target Neighborhood Hits	372	Shared Neighborhood Hits	17
SwissProt Accessions	Q6PRD1	Gene names	GPR179, GPR158L1
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 179 precursor (Probable G-protein coupled receptor 158-like 1).

GPC5B_HUMAN
θ value	θ > 10 (rank : 154)	NC score	0.103065 (rank : 92)
Query Neighborhood Hits	142	Target Neighborhood Hits	28	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NZH0, O75205, Q8NBZ8	Gene names	GPRC5B, RAIG2
Domain Architecture
Description	G-protein coupled receptor family C group 5 member B precursor (Retinoic acid-induced gene 2 protein) (RAIG-2) (A-69G12.1).

GPC5B_MOUSE
θ value	θ > 10 (rank : 155)	NC score	0.106990 (rank : 91)
Query Neighborhood Hits	142	Target Neighborhood Hits	33	Shared Neighborhood Hits	20
SwissProt Accessions	Q923Z0, Q8CCV3	Gene names	Gprc5b, Raig2
Domain Architecture
Description	G-protein coupled receptor family C group 5 member B precursor (Retinoic acid-induced gene 2 protein) (RAIG-2).

GRIA4_HUMAN
θ value	θ > 10 (rank : 156)	NC score	0.065160 (rank : 124)
Query Neighborhood Hits	142	Target Neighborhood Hits	45	Shared Neighborhood Hits	15
SwissProt Accessions	P48058	Gene names	GRIA4, GLUR4
Domain Architecture
Description	Glutamate receptor 4 precursor (GluR-4) (GluR4) (GluR-D) (Glutamate receptor ionotropic, AMPA 4) (AMPA-selective glutamate receptor 4).

GRIA4_MOUSE
θ value	θ > 10 (rank : 157)	NC score	0.065260 (rank : 123)
Query Neighborhood Hits	142	Target Neighborhood Hits	44	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Z2W8	Gene names	Gria4, Glur4
Domain Architecture
Description	Glutamate receptor 4 precursor (GluR-4) (GluR4) (GluR-D) (Glutamate receptor ionotropic, AMPA 4) (AMPA-selective glutamate receptor 4).

GRID1_HUMAN
θ value	θ > 10 (rank : 158)	NC score	0.056664 (rank : 130)
Query Neighborhood Hits	142	Target Neighborhood Hits	42	Shared Neighborhood Hits	15
SwissProt Accessions	Q9ULK0, Q8IXT3	Gene names	GRID1, KIAA1220
Domain Architecture
Description	Glutamate receptor delta-1 subunit precursor (GluR delta-1).

GRID1_MOUSE
θ value	θ > 10 (rank : 159)	NC score	0.056655 (rank : 131)
Query Neighborhood Hits	142	Target Neighborhood Hits	42	Shared Neighborhood Hits	15
SwissProt Accessions	Q61627	Gene names	Grid1
Domain Architecture
Description	Glutamate receptor delta-1 subunit precursor (GluR delta-1).

GRIK1_HUMAN
θ value	θ > 10 (rank : 160)	NC score	0.070159 (rank : 114)
Query Neighborhood Hits	142	Target Neighborhood Hits	48	Shared Neighborhood Hits	23
SwissProt Accessions	P39086, Q13001, Q86SU9	Gene names	GRIK1, GLUR5
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 1 precursor (Glutamate receptor 5) (GluR-5) (GluR5) (Excitatory amino acid receptor 3) (EAA3).

GRIK1_MOUSE
θ value	θ > 10 (rank : 161)	NC score	0.069648 (rank : 116)
Query Neighborhood Hits	142	Target Neighborhood Hits	46	Shared Neighborhood Hits	23
SwissProt Accessions	Q60934	Gene names	Grik1, Glur5
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 1 precursor (Glutamate receptor 5) (GluR-5) (GluR5).

GRIK2_HUMAN
θ value	θ > 10 (rank : 162)	NC score	0.071028 (rank : 113)
Query Neighborhood Hits	142	Target Neighborhood Hits	50	Shared Neighborhood Hits	24
SwissProt Accessions	Q13002	Gene names	GRIK2, GLUR6
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 2 precursor (Glutamate receptor 6) (GluR-6) (GluR6) (Excitatory amino acid receptor 4) (EAA4).

GRIK3_HUMAN
θ value	θ > 10 (rank : 163)	NC score	0.062153 (rank : 125)
Query Neighborhood Hits	142	Target Neighborhood Hits	41	Shared Neighborhood Hits	21
SwissProt Accessions	Q13003, Q13004, Q16136	Gene names	GRIK3, GLUR7
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 3 precursor (Glutamate receptor 7) (GluR-7) (GluR7) (Excitatory amino acid receptor 5) (EAA5).

GRIK5_HUMAN
θ value	θ > 10 (rank : 164)	NC score	0.057909 (rank : 128)
Query Neighborhood Hits	142	Target Neighborhood Hits	44	Shared Neighborhood Hits	13
SwissProt Accessions	Q16478	Gene names	GRIK5, GRIK2
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 5 precursor (Glutamate receptor KA-2) (KA2) (Excitatory amino acid receptor 2) (EAA2).

GRIK5_MOUSE
θ value	θ > 10 (rank : 165)	NC score	0.057984 (rank : 127)
Query Neighborhood Hits	142	Target Neighborhood Hits	47	Shared Neighborhood Hits	13
SwissProt Accessions	Q61626	Gene names	Grik5
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 5 precursor (Glutamate receptor KA-2) (KA2) (Glutamate receptor gamma-2) (GluR gamma-2).

GUC2C_HUMAN
θ value	θ > 10 (rank : 166)	NC score	0.057227 (rank : 129)
Query Neighborhood Hits	142	Target Neighborhood Hits	624	Shared Neighborhood Hits	8
SwissProt Accessions	P25092	Gene names	GUCY2C, GUC2C, STAR
Domain Architecture
Description	Heat-stable enterotoxin receptor precursor (GC-C) (Intestinal guanylate cyclase) (EC 4.6.1.2) (STA receptor) (hSTAR).

GUC2D_HUMAN
θ value	θ > 10 (rank : 167)	NC score	0.065952 (rank : 121)
Query Neighborhood Hits	142	Target Neighborhood Hits	715	Shared Neighborhood Hits	13
SwissProt Accessions	Q02846, Q6LEA7	Gene names	GUCY2D, CORD6, GUC1A4, GUC2D, RETGC, RETGC1
Domain Architecture
Description	Retinal guanylyl cyclase 1 precursor (EC 4.6.1.2) (Guanylate cyclase 2D, retinal) (RETGC-1) (Rod outer segment membrane guanylate cyclase) (ROS-GC).

GUC2E_MOUSE
θ value	θ > 10 (rank : 168)	NC score	0.066121 (rank : 120)
Query Neighborhood Hits	142	Target Neighborhood Hits	692	Shared Neighborhood Hits	12
SwissProt Accessions	P52785	Gene names	Gucy2e, Guc2e
Domain Architecture
Description	Guanylyl cyclase GC-E precursor (EC 4.6.1.2) (Guanylate cyclase 2E).

K0247_HUMAN
θ value	θ > 10 (rank : 169)	NC score	0.080914 (rank : 101)
Query Neighborhood Hits	142	Target Neighborhood Hits	42	Shared Neighborhood Hits	28
SwissProt Accessions	Q92537	Gene names	KIAA0247
Domain Architecture	No domain graphic available
Description	Protein KIAA0247 precursor.

MASP2_HUMAN
θ value	θ > 10 (rank : 170)	NC score	0.050486 (rank : 142)
Query Neighborhood Hits	142	Target Neighborhood Hits	364	Shared Neighborhood Hits	42
SwissProt Accessions	O00187, O75754, Q5TEQ5, Q5TER0, Q96QG4, Q9BZH0, Q9H498, Q9H499, Q9UBP3, Q9ULC7, Q9UMV3, Q9Y270	Gene names	MASP2
Domain Architecture
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

MASP2_MOUSE
θ value	θ > 10 (rank : 171)	NC score	0.056380 (rank : 132)
Query Neighborhood Hits	142	Target Neighborhood Hits	382	Shared Neighborhood Hits	44
SwissProt Accessions	Q91WP0, Q9QXA4, Q9QXD2, Q9QXD5, Q9Z338	Gene names	Masp2
Domain Architecture	No domain graphic available
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

NMD3A_HUMAN
θ value	θ > 10 (rank : 172)	NC score	0.051155 (rank : 139)
Query Neighborhood Hits	142	Target Neighborhood Hits	58	Shared Neighborhood Hits	18
SwissProt Accessions	Q8TCU5, Q8TF29, Q8WXI6	Gene names	GRIN3A, KIAA1973
Domain Architecture	No domain graphic available
Description	Glutamate [NMDA] receptor subunit 3A precursor (N-methyl-D-aspartate receptor subtype NR3A) (NMDAR-L).

NMDE2_HUMAN
θ value	θ > 10 (rank : 173)	NC score	0.054574 (rank : 133)
Query Neighborhood Hits	142	Target Neighborhood Hits	65	Shared Neighborhood Hits	17
SwissProt Accessions	Q13224, Q12919, Q13220, Q13225, Q9UM56	Gene names	GRIN2B
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 2 precursor (N-methyl D- aspartate receptor subtype 2B) (NR2B) (NMDAR2B) (N-methyl-D-aspartate receptor subunit 3) (NR3) (hNR3).

NMDE3_HUMAN
θ value	θ > 10 (rank : 174)	NC score	0.052940 (rank : 137)
Query Neighborhood Hits	142	Target Neighborhood Hits	110	Shared Neighborhood Hits	15
SwissProt Accessions	Q14957	Gene names	GRIN2C
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 3 precursor (N-methyl D- aspartate receptor subtype 2C) (NR2C) (NMDAR2C).

NMDE3_MOUSE
θ value	θ > 10 (rank : 175)	NC score	0.053306 (rank : 136)
Query Neighborhood Hits	142	Target Neighborhood Hits	86	Shared Neighborhood Hits	15
SwissProt Accessions	Q01098	Gene names	Grin2c
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 3 precursor (N-methyl D- aspartate receptor subtype 2C) (NR2C) (NMDAR2C).

NMDZ1_HUMAN
θ value	θ > 10 (rank : 176)	NC score	0.129999 (rank : 84)
Query Neighborhood Hits	142	Target Neighborhood Hits	77	Shared Neighborhood Hits	43
SwissProt Accessions	Q05586, P35437, Q12867, Q12868	Gene names	GRIN1, NMDAR1
Domain Architecture
Description	Glutamate [NMDA] receptor subunit zeta 1 precursor (N-methyl-D- aspartate receptor subunit NR1).

NMDZ1_MOUSE
θ value	θ > 10 (rank : 177)	NC score	0.129583 (rank : 85)
Query Neighborhood Hits	142	Target Neighborhood Hits	76	Shared Neighborhood Hits	42
SwissProt Accessions	P35438, Q8CFS4	Gene names	Grin1, Glurz1
Domain Architecture
Description	Glutamate [NMDA] receptor subunit zeta 1 precursor (N-methyl-D- aspartate receptor subunit NR1).

PAP2_HUMAN
θ value	θ > 10 (rank : 178)	NC score	0.130523 (rank : 83)
Query Neighborhood Hits	142	Target Neighborhood Hits	106	Shared Neighborhood Hits	42
SwissProt Accessions	Q9BXP8, Q96PH7, Q96PH8, Q9H4C9	Gene names	PAPPA2
Domain Architecture	No domain graphic available
Description	Pappalysin-2 precursor (EC 3.4.24.-) (Pregnancy-associated plasma protein-A2) (PAPP-A2) (Pregnancy-associated plasma protein-E1) (PAPP- E).

PAPPA_HUMAN
θ value	θ > 10 (rank : 179)	NC score	0.150800 (rank : 77)
Query Neighborhood Hits	142	Target Neighborhood Hits	161	Shared Neighborhood Hits	45
SwissProt Accessions	Q13219, Q08371, Q68G52, Q9UDK7	Gene names	PAPPA
Domain Architecture
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

PAPPA_MOUSE
θ value	θ > 10 (rank : 180)	NC score	0.149645 (rank : 78)
Query Neighborhood Hits	142	Target Neighborhood Hits	153	Shared Neighborhood Hits	44
SwissProt Accessions	Q8R4K8, Q80VW3, Q80YY1, Q8K423, Q8R4K7, Q9ES06, Q9JK57	Gene names	Pappa
Domain Architecture	No domain graphic available
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

PERT_MOUSE
θ value	θ > 10 (rank : 181)	NC score	0.051287 (rank : 138)
Query Neighborhood Hits	142	Target Neighborhood Hits	221	Shared Neighborhood Hits	41
SwissProt Accessions	P35419, Q8C8B1	Gene names	Tpo
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

SUSD1_HUMAN
θ value	θ > 10 (rank : 182)	NC score	0.080039 (rank : 102)
Query Neighborhood Hits	142	Target Neighborhood Hits	285	Shared Neighborhood Hits	37
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

SUSD3_HUMAN
θ value	θ > 10 (rank : 183)	NC score	0.068447 (rank : 117)
Query Neighborhood Hits	142	Target Neighborhood Hits	32	Shared Neighborhood Hits	25
SwissProt Accessions	Q96L08, Q49AA6, Q6UXV7	Gene names	SUSD3, UNQ9387/PRO34275
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 3.

SUSD3_MOUSE
θ value	θ > 10 (rank : 184)	NC score	0.116555 (rank : 89)
Query Neighborhood Hits	142	Target Neighborhood Hits	39	Shared Neighborhood Hits	32
SwissProt Accessions	Q9D176, Q80XL5, Q9CYV1, Q9DA86	Gene names	Susd3
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 3.

V2R1B_MOUSE
θ value	θ > 10 (rank : 185)	NC score	0.343354 (rank : 31)
Query Neighborhood Hits	142	Target Neighborhood Hits	39	Shared Neighborhood Hits	25
SwissProt Accessions	Q6TAC4, O70409	Gene names	V2r1b
Domain Architecture	No domain graphic available
Description	Vomeronasal type-2 receptor 1b precursor (Putative pheromone receptor V2R1b).

Hits sorted by NC score

GABR1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	142	Target Neighborhood Hits	142	Shared Neighborhood Hits	142
SwissProt Accessions	Q9UBS5, O95375, O95468, O95975, O96022, Q86W60, Q9UQQ0	Gene names	GABBR1, GPRC3A
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 1 precursor (GABA-B receptor 1) (GABA-B-R1) (Gb1).

GABR1_MOUSE
NC score	0.999599 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	142	Target Neighborhood Hits	139	Shared Neighborhood Hits	138
SwissProt Accessions	Q9WV18, Q9WU48, Q9WV15, Q9WV16, Q9WV17	Gene names	Gabbr1
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 1 precursor (GABA-B receptor 1) (GABA-B-R1) (Gb1).

GABR2_HUMAN
NC score	0.841848 (rank : 3)	θ value	1.02419e-128 (rank : 3)
Query Neighborhood Hits	142	Target Neighborhood Hits	101	Shared Neighborhood Hits	42
SwissProt Accessions	O75899, O75974, O75975, Q5VXZ2, Q8WX04, Q9P1R2, Q9UNR1, Q9UNS9	Gene names	GABBR2, GPR51, GPRC3B
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 2 precursor (GABA-B receptor 2) (GABA-B-R2) (Gb2) (GABABR2) (G-protein coupled receptor 51) (HG20).

GP156_HUMAN
NC score	0.446619 (rank : 4)	θ value	2.20605e-14 (rank : 4)
Query Neighborhood Hits	142	Target Neighborhood Hits	84	Shared Neighborhood Hits	13
SwissProt Accessions	Q8NFN8, Q86SN6	Gene names	GPR156, GABABL, PGR28
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 156 (GABAB-related G-protein coupled receptor) (G-protein coupled receptor PGR28).

TS1R3_HUMAN
NC score	0.438617 (rank : 5)	θ value	1.38499e-08 (rank : 9)
Query Neighborhood Hits	142	Target Neighborhood Hits	46	Shared Neighborhood Hits	30
SwissProt Accessions	Q7RTX0, Q5TA49, Q8NGW9	Gene names	TAS1R3, T1R3, TR3
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 3 precursor (Sweet taste receptor T1R3).

TS1R1_HUMAN
NC score	0.431342 (rank : 6)	θ value	1.53129e-07 (rank : 14)
Query Neighborhood Hits	142	Target Neighborhood Hits	72	Shared Neighborhood Hits	35
SwissProt Accessions	Q7RTX1, Q8NGZ7, Q8TDJ7, Q8TDJ8, Q8TDJ9, Q8TDK0	Gene names	TAS1R1, GPR70, T1R1, TR1
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 1 precursor (G-protein coupled receptor 70) (Gm148).

MGR4_HUMAN
NC score	0.430625 (rank : 7)	θ value	1.80886e-08 (rank : 10)
Query Neighborhood Hits	142	Target Neighborhood Hits	63	Shared Neighborhood Hits	35
SwissProt Accessions	Q14833, Q5SZ84	Gene names	GRM4, GPRC1D, MGLUR4
Domain Architecture
Description	Metabotropic glutamate receptor 4 precursor (mGluR4).

MGR8_MOUSE
NC score	0.427172 (rank : 8)	θ value	6.21693e-09 (rank : 7)
Query Neighborhood Hits	142	Target Neighborhood Hits	44	Shared Neighborhood Hits	30
SwissProt Accessions	P47743, Q6B964	Gene names	Grm8, Gprc1h, Mglur8
Domain Architecture
Description	Metabotropic glutamate receptor 8 precursor (mGluR8).

TS1R3_MOUSE
NC score	0.426901 (rank : 9)	θ value	1.09739e-05 (rank : 29)
Query Neighborhood Hits	142	Target Neighborhood Hits	49	Shared Neighborhood Hits	32
SwissProt Accessions	Q925D8, Q91VA4, Q923K0, Q925A4, Q925D9	Gene names	Tas1r3, Sac, T1r3, Tr3
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 3 precursor (Sweet taste receptor T1R3) (Saccharin preference protein).

MGR8_HUMAN
NC score	0.426484 (rank : 10)	θ value	8.11959e-09 (rank : 8)
Query Neighborhood Hits	142	Target Neighborhood Hits	49	Shared Neighborhood Hits	30
SwissProt Accessions	O00222, O15493, O95945, O95946, Q3MIV9, Q52M02, Q6J165	Gene names	GRM8, GPRC1H, MGLUR8
Domain Architecture
Description	Metabotropic glutamate receptor 8 precursor (mGluR8).

MGR7_MOUSE
NC score	0.425845 (rank : 11)	θ value	1.53129e-07 (rank : 13)
Query Neighborhood Hits	142	Target Neighborhood Hits	53	Shared Neighborhood Hits	31
SwissProt Accessions	Q68ED2	Gene names	Grm7, Gprc1g, Mglur7
Domain Architecture	No domain graphic available
Description	Metabotropic glutamate receptor 7 precursor (mGluR7).

MGR7_HUMAN
NC score	0.425525 (rank : 12)	θ value	1.53129e-07 (rank : 12)
Query Neighborhood Hits	142	Target Neighborhood Hits	52	Shared Neighborhood Hits	30
SwissProt Accessions	Q14831, Q8NFS2, Q8NFS3, Q8NFS4	Gene names	GRM7, GPRC1G, MGLUR7
Domain Architecture
Description	Metabotropic glutamate receptor 7 precursor (mGluR7).

V2RX_MOUSE
NC score	0.414804 (rank : 13)	θ value	4.92598e-06 (rank : 20)
Query Neighborhood Hits	142	Target Neighborhood Hits	45	Shared Neighborhood Hits	29
SwissProt Accessions	O70410	Gene names
Domain Architecture	No domain graphic available
Description	Vomeronasal type-2 receptor X precursor (Putative pheromone receptor V2RX).

TS1R2_MOUSE
NC score	0.414671 (rank : 14)	θ value	9.29e-05 (rank : 36)
Query Neighborhood Hits	142	Target Neighborhood Hits	69	Shared Neighborhood Hits	32
SwissProt Accessions	Q925I4, Q923J8	Gene names	Tas1r2, Gpr71, T1r2, Tr2
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 2 precursor (G-protein coupled receptor 71) (Sweet taste receptor T1R2).

MGR6_HUMAN
NC score	0.414452 (rank : 15)	θ value	6.43352e-06 (rank : 22)
Query Neighborhood Hits	142	Target Neighborhood Hits	58	Shared Neighborhood Hits	33
SwissProt Accessions	O15303	Gene names	GRM6, GPRC1F, MGLUR6
Domain Architecture
Description	Metabotropic glutamate receptor 6 precursor (mGluR6).

CASR_HUMAN
NC score	0.412987 (rank : 16)	θ value	4.92598e-06 (rank : 19)
Query Neighborhood Hits	142	Target Neighborhood Hits	71	Shared Neighborhood Hits	29
SwissProt Accessions	P41180, Q13912, Q16108, Q16109, Q16110, Q16379, Q4PJ19	Gene names	CASR, GPRC2A, PCAR1
Domain Architecture
Description	Extracellular calcium-sensing receptor precursor (CaSR) (Parathyroid Cell calcium-sensing receptor).

MGR6_MOUSE
NC score	0.412963 (rank : 17)	θ value	3.19293e-05 (rank : 33)
Query Neighborhood Hits	142	Target Neighborhood Hits	56	Shared Neighborhood Hits	34
SwissProt Accessions	Q5NCH9	Gene names	Grm6, Gprc1f, Mglur6
Domain Architecture	No domain graphic available
Description	Metabotropic glutamate receptor 6 precursor (mGluR6).

TS1R1_MOUSE
NC score	0.411575 (rank : 18)	θ value	6.43352e-06 (rank : 23)
Query Neighborhood Hits	142	Target Neighborhood Hits	57	Shared Neighborhood Hits	30
SwissProt Accessions	Q99PG6, Q6NS58, Q923J9, Q925I5, Q99PG5	Gene names	Tas1r1, Gpr70, T1r1, Tr1
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 1 precursor (G-protein coupled receptor 70).

CASR_MOUSE
NC score	0.411286 (rank : 19)	θ value	1.09739e-05 (rank : 26)
Query Neighborhood Hits	142	Target Neighborhood Hits	72	Shared Neighborhood Hits	29
SwissProt Accessions	Q9QY96, O08968, O88519, Q9QY95, Q9QZU8, Q9R1D6, Q9R1Y2	Gene names	Casr, Gprc2a
Domain Architecture
Description	Extracellular calcium-sensing receptor precursor (CaSR) (Parathyroid Cell calcium-sensing receptor).

MGR5_HUMAN
NC score	0.410516 (rank : 20)	θ value	0.000158464 (rank : 38)
Query Neighborhood Hits	142	Target Neighborhood Hits	72	Shared Neighborhood Hits	36
SwissProt Accessions	P41594	Gene names	GRM5, GPRC1E, MGLUR5
Domain Architecture
Description	Metabotropic glutamate receptor 5 precursor (mGluR5).

MGR1_HUMAN
NC score	0.409002 (rank : 21)	θ value	1.09739e-05 (rank : 28)
Query Neighborhood Hits	142	Target Neighborhood Hits	85	Shared Neighborhood Hits	32
SwissProt Accessions	Q13255, Q13256, Q14757, Q14758, Q5VTF7, Q5VTF8, Q9NU10, Q9UGS9, Q9UGT0	Gene names	GRM1, GPRC1A, MGLUR1
Domain Architecture
Description	Metabotropic glutamate receptor 1 precursor (mGluR1).

MGR1_MOUSE
NC score	0.408627 (rank : 22)	θ value	1.43324e-05 (rank : 31)
Query Neighborhood Hits	142	Target Neighborhood Hits	90	Shared Neighborhood Hits	33
SwissProt Accessions	P97772, Q6AXG4, Q9EPV6	Gene names	Grm1, Gprc1a, Mglur1
Domain Architecture
Description	Metabotropic glutamate receptor 1 precursor (mGluR1).

GPC6A_MOUSE
NC score	0.408472 (rank : 23)	θ value	1.43324e-05 (rank : 30)
Query Neighborhood Hits	142	Target Neighborhood Hits	57	Shared Neighborhood Hits	28
SwissProt Accessions	Q8K4Z6, Q5DK51, Q5DK52	Gene names	Gprc6a
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor family C group 6 member A precursor.

TS1R2_HUMAN
NC score	0.407079 (rank : 24)	θ value	0.00020696 (rank : 39)
Query Neighborhood Hits	142	Target Neighborhood Hits	48	Shared Neighborhood Hits	30
SwissProt Accessions	Q8TE23, Q5TZ19	Gene names	TAS1R2, GPR71, T1R2, TR2
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 2 precursor (G-protein coupled receptor 71) (Sweet taste receptor T1R2).

GPC6A_HUMAN
NC score	0.402170 (rank : 25)	θ value	0.000270298 (rank : 42)
Query Neighborhood Hits	142	Target Neighborhood Hits	53	Shared Neighborhood Hits	28
SwissProt Accessions	Q5T6X5, Q6JK43, Q6JK44, Q8NGU8, Q8NHZ9, Q8TDT6	Gene names	GPRC6A, GPCR33
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor family C group 6 member A precursor (hGPRC6A) (G-protein coupled receptor 33) (hGPCR33).

MGR3_MOUSE
NC score	0.401067 (rank : 26)	θ value	7.1131e-05 (rank : 34)
Query Neighborhood Hits	142	Target Neighborhood Hits	54	Shared Neighborhood Hits	31
SwissProt Accessions	Q9QYS2	Gene names	Grm3, Gprc1c, Mglur3
Domain Architecture
Description	Metabotropic glutamate receptor 3 precursor (mGluR3).

MGR2_HUMAN
NC score	0.398100 (rank : 27)	θ value	0.000786445 (rank : 46)
Query Neighborhood Hits	142	Target Neighborhood Hits	56	Shared Neighborhood Hits	33
SwissProt Accessions	Q14416, Q52MC6, Q9H3N6	Gene names	GRM2, GPRC1B, MGLUR2
Domain Architecture
Description	Metabotropic glutamate receptor 2 precursor (mGluR2).

MGR3_HUMAN
NC score	0.395505 (rank : 28)	θ value	0.000786445 (rank : 47)
Query Neighborhood Hits	142	Target Neighborhood Hits	58	Shared Neighborhood Hits	31
SwissProt Accessions	Q14832, Q75MV4, Q75N17, Q86YG6, Q8TBH9	Gene names	GRM3, GPRC1C, MGLUR3
Domain Architecture
Description	Metabotropic glutamate receptor 3 precursor (mGluR3).

GP156_MOUSE
NC score	0.393056 (rank : 29)	θ value	1.99992e-07 (rank : 15)
Query Neighborhood Hits	142	Target Neighborhood Hits	95	Shared Neighborhood Hits	14
SwissProt Accessions	Q6PCP7, Q8K452	Gene names	Gpr156, Gababl
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 156 (GABAB-related G-protein coupled receptor).

DAF_HUMAN
NC score	0.354203 (rank : 30)	θ value	4.45536e-07 (rank : 16)
Query Neighborhood Hits	142	Target Neighborhood Hits	97	Shared Neighborhood Hits	50
SwissProt Accessions	P08174, P09679, P78361	Gene names	CD55, CR, DAF
Domain Architecture
Description	Complement decay-accelerating factor precursor (CD55 antigen).

V2R1B_MOUSE
NC score	0.343354 (rank : 31)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	142	Target Neighborhood Hits	39	Shared Neighborhood Hits	25
SwissProt Accessions	Q6TAC4, O70409	Gene names	V2r1b
Domain Architecture	No domain graphic available
Description	Vomeronasal type-2 receptor 1b precursor (Putative pheromone receptor V2R1b).

ANPRC_MOUSE
NC score	0.343154 (rank : 32)	θ value	1.09739e-05 (rank : 25)
Query Neighborhood Hits	142	Target Neighborhood Hits	27	Shared Neighborhood Hits	21
SwissProt Accessions	P70180, P97804, Q9R025, Q9R027, Q9R028	Gene names	Npr3
Domain Architecture
Description	Atrial natriuretic peptide clearance receptor precursor (ANP-C) (ANPRC) (NPR-C) (Atrial natriuretic peptide C-type receptor) (EF-2).

ANPRC_HUMAN
NC score	0.337098 (rank : 33)	θ value	1.09739e-05 (rank : 24)
Query Neighborhood Hits	142	Target Neighborhood Hits	27	Shared Neighborhood Hits	20
SwissProt Accessions	P17342	Gene names	NPR3, ANPRC
Domain Architecture
Description	Atrial natriuretic peptide clearance receptor precursor (ANP-C) (ANPRC) (NPR-C) (Atrial natriuretic peptide C-type receptor).

CR1_HUMAN
NC score	0.328548 (rank : 34)	θ value	3.19293e-05 (rank : 32)
Query Neighborhood Hits	142	Target Neighborhood Hits	108	Shared Neighborhood Hits	48
SwissProt Accessions	P17927, Q16745, Q9UQV2	Gene names	CR1, C3BR
Domain Architecture
Description	Complement receptor type 1 precursor (C3b/C4b receptor) (CD35 antigen).

C4BB_HUMAN
NC score	0.324147 (rank : 35)	θ value	0.0148317 (rank : 59)
Query Neighborhood Hits	142	Target Neighborhood Hits	77	Shared Neighborhood Hits	48
SwissProt Accessions	P20851	Gene names	C4BPB
Domain Architecture
Description	C4b-binding protein beta chain precursor.

CRRY_MOUSE
NC score	0.323227 (rank : 36)	θ value	0.00298849 (rank : 51)
Query Neighborhood Hits	142	Target Neighborhood Hits	84	Shared Neighborhood Hits	49
SwissProt Accessions	Q64735, Q3TV30, Q58E68, Q61447, Q61449, Q8CF59, Q8K328	Gene names	Crry, Cry
Domain Architecture	No domain graphic available
Description	Complement regulatory protein Crry precursor (Protein p65).

CR2_MOUSE
NC score	0.317675 (rank : 37)	θ value	0.00134147 (rank : 50)
Query Neighborhood Hits	142	Target Neighborhood Hits	101	Shared Neighborhood Hits	48
SwissProt Accessions	P19070	Gene names	Cr2
Domain Architecture
Description	Complement receptor type 2 precursor (Cr2) (Complement C3d receptor) (CD21 antigen).

CR2_HUMAN
NC score	0.317294 (rank : 38)	θ value	0.00102713 (rank : 48)
Query Neighborhood Hits	142	Target Neighborhood Hits	89	Shared Neighborhood Hits	48
SwissProt Accessions	P20023, Q13866, Q14212	Gene names	CR2, C3DR
Domain Architecture
Description	Complement receptor type 2 precursor (Cr2) (Complement C3d receptor) (Epstein-Barr virus receptor) (EBV receptor) (CD21 antigen).

ZP3R_MOUSE
NC score	0.312720 (rank : 39)	θ value	0.00298849 (rank : 54)
Query Neighborhood Hits	142	Target Neighborhood Hits	81	Shared Neighborhood Hits	48
SwissProt Accessions	Q60736	Gene names	Zp3r, Sp56
Domain Architecture
Description	Zona pellucida sperm-binding protein 3 receptor precursor (Sperm fertilization protein 56) (sp56).

DAF1_MOUSE
NC score	0.310954 (rank : 40)	θ value	0.000602161 (rank : 45)
Query Neighborhood Hits	142	Target Neighborhood Hits	204	Shared Neighborhood Hits	49
SwissProt Accessions	Q61475, P97732, Q61397	Gene names	Cd55a, Daf1
Domain Architecture
Description	Complement decay-accelerating factor, GPI-anchored precursor (DAF-GPI) (CD55 antigen).

F13B_MOUSE
NC score	0.306724 (rank : 41)	θ value	0.00102713 (rank : 49)
Query Neighborhood Hits	142	Target Neighborhood Hits	93	Shared Neighborhood Hits	48
SwissProt Accessions	Q07968	Gene names	F13b, Cf13b
Domain Architecture
Description	Coagulation factor XIII B chain precursor (Protein-glutamine gamma- glutamyltransferase B chain) (Transglutaminase B chain).

MCP_MOUSE
NC score	0.306280 (rank : 42)	θ value	0.0148317 (rank : 60)
Query Neighborhood Hits	142	Target Neighborhood Hits	79	Shared Neighborhood Hits	48
SwissProt Accessions	O88174, Q9R0R9	Gene names	Cd46, Mcp
Domain Architecture	No domain graphic available
Description	Membrane cofactor protein precursor (CD46 antigen).

CFAH_HUMAN
NC score	0.304511 (rank : 43)	θ value	0.000270298 (rank : 40)
Query Neighborhood Hits	142	Target Neighborhood Hits	101	Shared Neighborhood Hits	48
SwissProt Accessions	P08603, P78435, Q14570, Q38G77, Q5TFM3, Q8N708, Q9NU86	Gene names	CFH, HF, HF1
Domain Architecture
Description	Complement factor H precursor (H factor 1).

C4BP_MOUSE
NC score	0.302951 (rank : 44)	θ value	0.0961366 (rank : 72)
Query Neighborhood Hits	142	Target Neighborhood Hits	91	Shared Neighborhood Hits	48
SwissProt Accessions	P08607	Gene names	C4bpa, C4bp
Domain Architecture
Description	C4b-binding protein precursor (C4bp).

MCP_HUMAN
NC score	0.301708 (rank : 45)	θ value	0.0961366 (rank : 73)
Query Neighborhood Hits	142	Target Neighborhood Hits	82	Shared Neighborhood Hits	48
SwissProt Accessions	P15529, Q15429, Q53GV9, Q5HY94, Q5VWS6, Q5VWS7, Q5VWS8, Q5VWS9, Q5VWT0, Q5VWT1, Q5VWT2, Q6N0A1, Q7Z3R5, Q9NNW2, Q9NNW3, Q9NNW4	Gene names	CD46, MCP
Domain Architecture
Description	Membrane cofactor protein precursor (Trophoblast leukocyte common antigen) (TLX) (CD46 antigen).

DAF2_MOUSE
NC score	0.299724 (rank : 46)	θ value	0.0252991 (rank : 61)
Query Neighborhood Hits	142	Target Neighborhood Hits	114	Shared Neighborhood Hits	48
SwissProt Accessions	Q61476	Gene names	Cd55b, Daf2
Domain Architecture
Description	Complement decay-accelerating factor transmembrane isoform precursor (DAF-TM) (CD55 antigen).

C4BP_HUMAN
NC score	0.295637 (rank : 47)	θ value	0.21417 (rank : 77)
Query Neighborhood Hits	142	Target Neighborhood Hits	92	Shared Neighborhood Hits	48
SwissProt Accessions	P04003	Gene names	C4BPA, C4BP
Domain Architecture
Description	C4b-binding protein alpha chain precursor (C4bp) (Proline-rich protein) (PRP).

FHR5_HUMAN
NC score	0.293859 (rank : 48)	θ value	0.00390308 (rank : 55)
Query Neighborhood Hits	142	Target Neighborhood Hits	77	Shared Neighborhood Hits	46
SwissProt Accessions	Q9BXR6	Gene names	CFHL5, FHR5
Domain Architecture
Description	Complement factor H-related protein 5 precursor (FHR-5).

FHR1_HUMAN
NC score	0.292516 (rank : 49)	θ value	0.000270298 (rank : 41)
Query Neighborhood Hits	142	Target Neighborhood Hits	80	Shared Neighborhood Hits	47
SwissProt Accessions	Q03591, Q9UJ17	Gene names	CFHL1, CFHL, FHR1, HFL1
Domain Architecture
Description	Complement factor H-related protein 1 precursor (FHR-1) (H factor-like protein 1) (H-factor-like 1) (H36).

F13B_HUMAN
NC score	0.292252 (rank : 50)	θ value	0.0563607 (rank : 68)
Query Neighborhood Hits	142	Target Neighborhood Hits	84	Shared Neighborhood Hits	47
SwissProt Accessions	P05160	Gene names	F13B
Domain Architecture
Description	Coagulation factor XIII B chain precursor (Protein-glutamine gamma- glutamyltransferase B chain) (Transglutaminase B chain) (Fibrin- stabilizing factor B subunit).

APOH_HUMAN
NC score	0.292136 (rank : 51)	θ value	0.125558 (rank : 74)
Query Neighborhood Hits	142	Target Neighborhood Hits	75	Shared Neighborhood Hits	48
SwissProt Accessions	P02749, Q9UCN7	Gene names	APOH, B2G1
Domain Architecture
Description	Beta-2-glycoprotein 1 precursor (Beta-2-glycoprotein I) (Apolipoprotein H) (Apo-H) (B2GPI) (Beta(2)GPI) (Activated protein C- binding protein) (APC inhibitor) (Anticardiolipin cofactor).

CFAH_MOUSE
NC score	0.287860 (rank : 52)	θ value	0.0563607 (rank : 66)
Query Neighborhood Hits	142	Target Neighborhood Hits	112	Shared Neighborhood Hits	48
SwissProt Accessions	P06909	Gene names	Cfh, Hf1
Domain Architecture
Description	Complement factor H precursor (Protein beta-1-H).

APOH_MOUSE
NC score	0.275144 (rank : 53)	θ value	3.0926 (rank : 101)
Query Neighborhood Hits	142	Target Neighborhood Hits	74	Shared Neighborhood Hits	48
SwissProt Accessions	Q01339	Gene names	Apoh, B2gp1
Domain Architecture
Description	Beta-2-glycoprotein 1 precursor (Beta-2-glycoprotein I) (Apolipoprotein H) (Apo-H) (B2GPI) (Beta(2)GPI) (Activated protein C- binding protein) (APC inhibitor).

SUSD4_HUMAN
NC score	0.272506 (rank : 54)	θ value	0.0736092 (rank : 71)
Query Neighborhood Hits	142	Target Neighborhood Hits	88	Shared Neighborhood Hits	48
SwissProt Accessions	Q5VX71, Q6UX62, Q9BSR0, Q9NWG0	Gene names	SUSD4
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 4 precursor.

LYAM3_HUMAN
NC score	0.269600 (rank : 55)	θ value	0.00035302 (rank : 44)
Query Neighborhood Hits	142	Target Neighborhood Hits	378	Shared Neighborhood Hits	48
SwissProt Accessions	P16109, Q8IVD1	Gene names	SELP, GMRP
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

LYAM3_MOUSE
NC score	0.269442 (rank : 56)	θ value	9.29e-05 (rank : 35)
Query Neighborhood Hits	142	Target Neighborhood Hits	390	Shared Neighborhood Hits	48
SwissProt Accessions	Q01102	Gene names	Selp, Grmp
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

SUSD4_MOUSE
NC score	0.266962 (rank : 57)	θ value	0.279714 (rank : 82)
Query Neighborhood Hits	142	Target Neighborhood Hits	122	Shared Neighborhood Hits	48
SwissProt Accessions	Q8BH32, Q8VC43	Gene names	Susd4
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 4 precursor.

LYAM2_MOUSE
NC score	0.266742 (rank : 58)	θ value	1.09739e-05 (rank : 27)
Query Neighborhood Hits	142	Target Neighborhood Hits	420	Shared Neighborhood Hits	49
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

CSMD3_HUMAN
NC score	0.266177 (rank : 59)	θ value	2.21117e-06 (rank : 18)
Query Neighborhood Hits	142	Target Neighborhood Hits	199	Shared Neighborhood Hits	48
SwissProt Accessions	Q7Z407, Q96PZ3	Gene names	CSMD3, KIAA1894
Domain Architecture
Description	CUB and sushi domain-containing protein 3 precursor (CUB and sushi multiple domains protein 3).

CSMD1_HUMAN
NC score	0.260964 (rank : 60)	θ value	6.43352e-06 (rank : 21)
Query Neighborhood Hits	142	Target Neighborhood Hits	176	Shared Neighborhood Hits	48
SwissProt Accessions	Q96PZ7, Q96QU9, Q96RM4	Gene names	CSMD1, KIAA1890
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

FHR3_HUMAN
NC score	0.260557 (rank : 61)	θ value	0.0330416 (rank : 64)
Query Neighborhood Hits	142	Target Neighborhood Hits	74	Shared Neighborhood Hits	45
SwissProt Accessions	Q02985, Q9UJ16	Gene names	CFHL3, FHR3
Domain Architecture
Description	Complement factor H-related protein 3 precursor (FHR-3) (H factor-like protein 3) (DOWN16).

LYAM2_HUMAN
NC score	0.253976 (rank : 62)	θ value	0.00298849 (rank : 52)
Query Neighborhood Hits	142	Target Neighborhood Hits	394	Shared Neighborhood Hits	48
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

CSMD2_HUMAN
NC score	0.252574 (rank : 63)	θ value	0.000121331 (rank : 37)
Query Neighborhood Hits	142	Target Neighborhood Hits	188	Shared Neighborhood Hits	48
SwissProt Accessions	Q7Z408, Q5VT59, Q8N963, Q96Q03, Q9H4V7, Q9H4V8, Q9H4V9, Q9H4W0, Q9H4W1, Q9H4W2, Q9H4W3, Q9H4W4, Q9HCY5, Q9HCY6, Q9HCY7	Gene names	CSMD2, KIAA1884
Domain Architecture
Description	CUB and sushi domain-containing protein 2 (CUB and sushi multiple domains protein 2).

CSMD1_MOUSE
NC score	0.252453 (rank : 64)	θ value	0.00035302 (rank : 43)
Query Neighborhood Hits	142	Target Neighborhood Hits	193	Shared Neighborhood Hits	48
SwissProt Accessions	Q923L3, Q8BUV1, Q8BYQ3	Gene names	Csmd1
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

FHR4_HUMAN
NC score	0.246503 (rank : 65)	θ value	0.279714 (rank : 80)
Query Neighborhood Hits	142	Target Neighborhood Hits	75	Shared Neighborhood Hits	44
SwissProt Accessions	Q92496, Q9UJY6	Gene names	CFHL4, FHR4
Domain Architecture
Description	Complement factor H-related protein 4 precursor (FHR-4).

FHR2_HUMAN
NC score	0.244172 (rank : 66)	θ value	0.813845 (rank : 84)
Query Neighborhood Hits	142	Target Neighborhood Hits	63	Shared Neighborhood Hits	45
SwissProt Accessions	P36980, Q14310	Gene names	CFHL2, FHR2, HFL3
Domain Architecture
Description	Complement factor H-related protein 2 precursor (FHR-2) (H factor-like protein 2) (H factor-like 3) (DDESK59).

SRPX_MOUSE
NC score	0.243520 (rank : 67)	θ value	1.38821 (rank : 93)
Query Neighborhood Hits	142	Target Neighborhood Hits	75	Shared Neighborhood Hits	47
SwissProt Accessions	Q9R0M3, Q9R0M2	Gene names	Srpx
Domain Architecture	No domain graphic available
Description	Sushi-repeat-containing protein SRPX precursor (DRS protein).

SUSD2_HUMAN
NC score	0.238124 (rank : 68)	θ value	0.00298849 (rank : 53)
Query Neighborhood Hits	142	Target Neighborhood Hits	99	Shared Neighborhood Hits	48
SwissProt Accessions	Q9UGT4, Q9H5Y6	Gene names	SUSD2
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 2 precursor.

SEZ6L_HUMAN
NC score	0.237703 (rank : 69)	θ value	0.0736092 (rank : 70)
Query Neighborhood Hits	142	Target Neighborhood Hits	289	Shared Neighborhood Hits	49
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.

SRPX_HUMAN
NC score	0.237504 (rank : 70)	θ value	1.81305 (rank : 97)
Query Neighborhood Hits	142	Target Neighborhood Hits	69	Shared Neighborhood Hits	47
SwissProt Accessions	P78539, Q99652, Q99913	Gene names	SRPX, ETX1
Domain Architecture
Description	Sushi repeat-containing protein SRPX precursor.

SUSD2_MOUSE
NC score	0.233876 (rank : 71)	θ value	0.00869519 (rank : 58)
Query Neighborhood Hits	142	Target Neighborhood Hits	104	Shared Neighborhood Hits	48
SwissProt Accessions	Q9DBX3, Q8BY19, Q8BYN0, Q8BYZ3, Q8BYZ9, Q8BZQ4, Q8C179	Gene names	Susd2
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 2 precursor.

LYAM1_MOUSE
NC score	0.196092 (rank : 72)	θ value	0.125558 (rank : 75)
Query Neighborhood Hits	142	Target Neighborhood Hits	332	Shared Neighborhood Hits	41
SwissProt Accessions	P18337	Gene names	Sell, Lnhr, Ly-22
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Lymphocyte antigen 22) (Ly-22) (Lymphocyte surface MEL-14 antigen) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

LYAM1_HUMAN
NC score	0.189960 (rank : 73)	θ value	1.38821 (rank : 92)
Query Neighborhood Hits	142	Target Neighborhood Hits	315	Shared Neighborhood Hits	44
SwissProt Accessions	P14151, P15023	Gene names	SELL, LNHR, LYAM1
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Leukocyte surface antigen Leu-8) (TQ1) (gp90-MEL) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

CO2_HUMAN
NC score	0.165973 (rank : 74)	θ value	0.0563607 (rank : 67)
Query Neighborhood Hits	142	Target Neighborhood Hits	258	Shared Neighborhood Hits	47
SwissProt Accessions	P06681, O19694, Q13904	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

CFAB_HUMAN
NC score	0.161694 (rank : 75)	θ value	0.21417 (rank : 78)
Query Neighborhood Hits	142	Target Neighborhood Hits	251	Shared Neighborhood Hits	48
SwissProt Accessions	P00751, O15006, Q29944, Q96HX6, Q9BTF5, Q9BX92	Gene names	CFB, BF
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) (Properdin factor B) (Glycine-rich beta glycoprotein) (GBG) (PBF2) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

CFAB_MOUSE
NC score	0.155331 (rank : 76)	θ value	0.813845 (rank : 83)
Query Neighborhood Hits	142	Target Neighborhood Hits	262	Shared Neighborhood Hits	47
SwissProt Accessions	P04186	Gene names	Cfb, Bf, H2-Bf
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

PAPPA_HUMAN
NC score	0.150800 (rank : 77)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	142	Target Neighborhood Hits	161	Shared Neighborhood Hits	45
SwissProt Accessions	Q13219, Q08371, Q68G52, Q9UDK7	Gene names	PAPPA
Domain Architecture
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

PAPPA_MOUSE
NC score	0.149645 (rank : 78)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	142	Target Neighborhood Hits	153	Shared Neighborhood Hits	44
SwissProt Accessions	Q8R4K8, Q80VW3, Q80YY1, Q8K423, Q8R4K7, Q9ES06, Q9JK57	Gene names	Pappa
Domain Architecture	No domain graphic available
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

ANPRB_MOUSE
NC score	0.143530 (rank : 79)	θ value	2.28291e-11 (rank : 5)
Query Neighborhood Hits	142	Target Neighborhood Hits	607	Shared Neighborhood Hits	18
SwissProt Accessions	Q6VVW5, Q6VVW3, Q6VVW4, Q8CGA9	Gene names	Npr2
Domain Architecture	No domain graphic available
Description	Atrial natriuretic peptide receptor B precursor (ANP-B) (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor).

CO2_MOUSE
NC score	0.143267 (rank : 80)	θ value	0.0736092 (rank : 69)
Query Neighborhood Hits	142	Target Neighborhood Hits	250	Shared Neighborhood Hits	46
SwissProt Accessions	P21180	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

ANPRB_HUMAN
NC score	0.136526 (rank : 81)	θ value	1.47974e-10 (rank : 6)
Query Neighborhood Hits	142	Target Neighborhood Hits	646	Shared Neighborhood Hits	19
SwissProt Accessions	P20594, O60871, Q9UQ50	Gene names	NPR2, ANPRB
Domain Architecture
Description	Atrial natriuretic peptide receptor B precursor (ANP-B) (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor).

CO6_HUMAN
NC score	0.132321 (rank : 82)	θ value	0.0431538 (rank : 65)
Query Neighborhood Hits	142	Target Neighborhood Hits	331	Shared Neighborhood Hits	45
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

PAP2_HUMAN
NC score	0.130523 (rank : 83)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	142	Target Neighborhood Hits	106	Shared Neighborhood Hits	42
SwissProt Accessions	Q9BXP8, Q96PH7, Q96PH8, Q9H4C9	Gene names	PAPPA2
Domain Architecture	No domain graphic available
Description	Pappalysin-2 precursor (EC 3.4.24.-) (Pregnancy-associated plasma protein-A2) (PAPP-A2) (Pregnancy-associated plasma protein-E1) (PAPP- E).

NMDZ1_HUMAN
NC score	0.129999 (rank : 84)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	142	Target Neighborhood Hits	77	Shared Neighborhood Hits	43
SwissProt Accessions	Q05586, P35437, Q12867, Q12868	Gene names	GRIN1, NMDAR1
Domain Architecture
Description	Glutamate [NMDA] receptor subunit zeta 1 precursor (N-methyl-D- aspartate receptor subunit NR1).

NMDZ1_MOUSE
NC score	0.129583 (rank : 85)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	142	Target Neighborhood Hits	76	Shared Neighborhood Hits	42
SwissProt Accessions	P35438, Q8CFS4	Gene names	Grin1, Glurz1
Domain Architecture
Description	Glutamate [NMDA] receptor subunit zeta 1 precursor (N-methyl-D- aspartate receptor subunit NR1).

ANPRA_MOUSE
NC score	0.127195 (rank : 86)	θ value	1.53129e-07 (rank : 11)
Query Neighborhood Hits	142	Target Neighborhood Hits	600	Shared Neighborhood Hits	15
SwissProt Accessions	P18293	Gene names	Npr1, Npra
Domain Architecture
Description	Atrial natriuretic peptide receptor A precursor (ANP-A) (ANPRA) (GC-A) (Guanylate cyclase) (EC 4.6.1.2) (NPR-A) (Atrial natriuretic peptide A-type receptor).

ANPRA_HUMAN
NC score	0.125362 (rank : 87)	θ value	5.81887e-07 (rank : 17)
Query Neighborhood Hits	142	Target Neighborhood Hits	612	Shared Neighborhood Hits	16
SwissProt Accessions	P16066, Q6P4Q3	Gene names	NPR1, ANPRA
Domain Architecture
Description	Atrial natriuretic peptide receptor A precursor (ANP-A) (ANPRA) (GC-A) (Guanylate cyclase) (EC 4.6.1.2) (NPR-A) (Atrial natriuretic peptide A-type receptor).

CO7_HUMAN
NC score	0.119791 (rank : 88)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	142	Target Neighborhood Hits	278	Shared Neighborhood Hits	43
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

SUSD3_MOUSE
NC score	0.116555 (rank : 89)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	142	Target Neighborhood Hits	39	Shared Neighborhood Hits	32
SwissProt Accessions	Q9D176, Q80XL5, Q9CYV1, Q9DA86	Gene names	Susd3
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 3.

GP158_HUMAN
NC score	0.116436 (rank : 90)	θ value	1.06291 (rank : 88)
Query Neighborhood Hits	142	Target Neighborhood Hits	221	Shared Neighborhood Hits	20
SwissProt Accessions	Q5T848, Q6QR81, Q9ULT3	Gene names	GPR158, KIAA1136
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 158 precursor.

GPC5B_MOUSE
NC score	0.106990 (rank : 91)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	142	Target Neighborhood Hits	33	Shared Neighborhood Hits	20
SwissProt Accessions	Q923Z0, Q8CCV3	Gene names	Gprc5b, Raig2
Domain Architecture
Description	G-protein coupled receptor family C group 5 member B precursor (Retinoic acid-induced gene 2 protein) (RAIG-2).

GPC5B_HUMAN
NC score	0.103065 (rank : 92)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	142	Target Neighborhood Hits	28	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NZH0, O75205, Q8NBZ8	Gene names	GPRC5B, RAIG2
Domain Architecture
Description	G-protein coupled receptor family C group 5 member B precursor (Retinoic acid-induced gene 2 protein) (RAIG-2) (A-69G12.1).

GUC2F_HUMAN
NC score	0.096785 (rank : 93)	θ value	0.21417 (rank : 79)
Query Neighborhood Hits	142	Target Neighborhood Hits	740	Shared Neighborhood Hits	27
SwissProt Accessions	P51841, Q9UJF1	Gene names	GUCY2F, GUC2F, RETGC2
Domain Architecture
Description	Retinal guanylyl cyclase 2 precursor (EC 4.6.1.2) (Guanylate cyclase 2F, retinal) (RETGC-2) (Rod outer segment membrane guanylate cyclase 2) (ROS-GC2) (Guanylate cyclase F) (GC-F).

GUC2G_MOUSE
NC score	0.096647 (rank : 94)	θ value	5.27518 (rank : 115)
Query Neighborhood Hits	142	Target Neighborhood Hits	644	Shared Neighborhood Hits	31
SwissProt Accessions	Q6TL19, Q8BWU7	Gene names	Gucy2g
Domain Architecture	No domain graphic available
Description	Guanylate cyclase 2G precursor (EC 4.6.1.2) (Guanylyl cyclase receptor G) (mGC-G).

GP158_MOUSE
NC score	0.094516 (rank : 95)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	142	Target Neighborhood Hits	82	Shared Neighborhood Hits	17
SwissProt Accessions	Q8C419, Q8CHB0	Gene names	Gpr158, Kiaa1136
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 158 precursor.

GRIA2_MOUSE
NC score	0.089522 (rank : 96)	θ value	0.00665767 (rank : 57)
Query Neighborhood Hits	142	Target Neighborhood Hits	47	Shared Neighborhood Hits	15
SwissProt Accessions	P23819, Q61604, Q61605, Q8BG69, Q8BXU3, Q9D6D3	Gene names	Gria2, Glur2
Domain Architecture
Description	Glutamate receptor 2 precursor (GluR-2) (GluR-B) (GluR-K2) (Glutamate receptor ionotropic, AMPA 2) (AMPA-selective glutamate receptor 2).

GRIA2_HUMAN
NC score	0.089487 (rank : 97)	θ value	0.00665767 (rank : 56)
Query Neighborhood Hits	142	Target Neighborhood Hits	47	Shared Neighborhood Hits	15
SwissProt Accessions	P42262, Q96FP6	Gene names	GRIA2, GLUR2
Domain Architecture
Description	Glutamate receptor 2 precursor (GluR-2) (GluR-B) (GluR-K2) (Glutamate receptor ionotropic, AMPA 2) (AMPA-selective glutamate receptor 2).

GRIA1_MOUSE
NC score	0.086358 (rank : 98)	θ value	0.0252991 (rank : 63)
Query Neighborhood Hits	142	Target Neighborhood Hits	46	Shared Neighborhood Hits	16
SwissProt Accessions	P23818	Gene names	Gria1, Glur1
Domain Architecture
Description	Glutamate receptor 1 precursor (GluR-1) (GluR-A) (GluR-K1) (Glutamate receptor ionotropic, AMPA 1) (AMPA-selective glutamate receptor 1).

GRIA1_HUMAN
NC score	0.086102 (rank : 99)	θ value	0.0252991 (rank : 62)
Query Neighborhood Hits	142	Target Neighborhood Hits	45	Shared Neighborhood Hits	15
SwissProt Accessions	P42261	Gene names	GRIA1, GLUH1, GLUR1
Domain Architecture
Description	Glutamate receptor 1 precursor (GluR-1) (GluR-A) (GluR-K1) (Glutamate receptor ionotropic, AMPA 1) (AMPA-selective glutamate receptor 1).

GCYB2_HUMAN
NC score	0.081117 (rank : 100)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	142	Target Neighborhood Hits	61	Shared Neighborhood Hits	6
SwissProt Accessions	O75343, Q9NZ64	Gene names	GUCY1B2
Domain Architecture
Description	Guanylate cyclase soluble subunit beta-2 (EC 4.6.1.2) (GCS-beta-2).

K0247_HUMAN
NC score	0.080914 (rank : 101)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	142	Target Neighborhood Hits	42	Shared Neighborhood Hits	28
SwissProt Accessions	Q92537	Gene names	KIAA0247
Domain Architecture	No domain graphic available
Description	Protein KIAA0247 precursor.

SUSD1_HUMAN
NC score	0.080039 (rank : 102)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	142	Target Neighborhood Hits	285	Shared Neighborhood Hits	37
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

GP179_HUMAN
NC score	0.079502 (rank : 103)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	142	Target Neighborhood Hits	372	Shared Neighborhood Hits	17
SwissProt Accessions	Q6PRD1	Gene names	GPR179, GPR158L1
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 179 precursor (Probable G-protein coupled receptor 158-like 1).

GCYA2_HUMAN
NC score	0.074837 (rank : 104)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	142	Target Neighborhood Hits	50	Shared Neighborhood Hits	6
SwissProt Accessions	P33402	Gene names	GUCY1A2, GUC1A2, GUCSA2
Domain Architecture
Description	Guanylate cyclase soluble subunit alpha-2 (EC 4.6.1.2) (GCS-alpha-2).

GRIA3_MOUSE
NC score	0.074603 (rank : 105)	θ value	1.38821 (rank : 91)
Query Neighborhood Hits	142	Target Neighborhood Hits	39	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Z2W9, Q5DTJ0	Gene names	Gria3, Glur3, Kiaa4184
Domain Architecture	No domain graphic available
Description	Glutamate receptor 3 precursor (GluR-3) (GluR-C) (GluR-K3) (Glutamate receptor ionotropic, AMPA 3) (AMPA-selective glutamate receptor 3).

GCYB1_MOUSE
NC score	0.074179 (rank : 106)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	142	Target Neighborhood Hits	40	Shared Neighborhood Hits	6
SwissProt Accessions	O54865	Gene names	Gucy1b3
Domain Architecture	No domain graphic available
Description	Guanylate cyclase soluble subunit beta-1 (EC 4.6.1.2) (GCS-beta-1) (Soluble guanylate cyclase small subunit).

GCYB1_HUMAN
NC score	0.074052 (rank : 107)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	142	Target Neighborhood Hits	41	Shared Neighborhood Hits	6
SwissProt Accessions	Q02153, Q86WY5	Gene names	GUCY1B3, GUC1B3, GUCSB3, GUCY1B1
Domain Architecture
Description	Guanylate cyclase soluble subunit beta-1 (EC 4.6.1.2) (GCS-beta-1) (Soluble guanylate cyclase small subunit) (GCS-beta-3).

NMDE4_HUMAN
NC score	0.072748 (rank : 108)	θ value	0.163984 (rank : 76)
Query Neighborhood Hits	142	Target Neighborhood Hits	133	Shared Neighborhood Hits	20
SwissProt Accessions	O15399	Gene names	GRIN2D
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 4 precursor (N-methyl D- aspartate receptor subtype 2D) (NR2D) (NMDAR2D) (EB11).

GCYA3_MOUSE
NC score	0.072540 (rank : 109)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	142	Target Neighborhood Hits	41	Shared Neighborhood Hits	6
SwissProt Accessions	Q9ERL9, Q9DBQ3	Gene names	Gucy1a3, Gucy1a1
Domain Architecture
Description	Guanylate cyclase soluble subunit alpha-3 (EC 4.6.1.2) (GCS-alpha-3) (Soluble guanylate cyclase large subunit) (GCS-alpha-1).

GCYA3_HUMAN
NC score	0.072505 (rank : 110)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	142	Target Neighborhood Hits	36	Shared Neighborhood Hits	6
SwissProt Accessions	Q02108, O43843, Q8TAH3	Gene names	GUCY1A3, GUC1A3, GUCSA3, GUCY1A1
Domain Architecture
Description	Guanylate cyclase soluble subunit alpha-3 (EC 4.6.1.2) (GCS-alpha-3) (Soluble guanylate cyclase large subunit) (GCS-alpha-1).

GRIA3_HUMAN
NC score	0.072167 (rank : 111)	θ value	3.0926 (rank : 102)
Query Neighborhood Hits	142	Target Neighborhood Hits	40	Shared Neighborhood Hits	16
SwissProt Accessions	P42263, Q4VXD5, Q4VXD6, Q9HDA0, Q9HDA1, Q9HDA2	Gene names	GRIA3, GLUR3, GLURC
Domain Architecture
Description	Glutamate receptor 3 precursor (GluR-3) (GluR-C) (GluR-K3) (Glutamate receptor ionotropic, AMPA 3) (AMPA-selective glutamate receptor 3).

GRIK4_HUMAN
NC score	0.071071 (rank : 112)	θ value	1.06291 (rank : 89)
Query Neighborhood Hits	142	Target Neighborhood Hits	42	Shared Neighborhood Hits	19
SwissProt Accessions	Q16099	Gene names	GRIK4, GRIK
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 4 precursor (Glutamate receptor KA-1) (KA1) (Excitatory amino acid receptor 1) (EAA1).

GRIK2_HUMAN
NC score	0.071028 (rank : 113)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	142	Target Neighborhood Hits	50	Shared Neighborhood Hits	24
SwissProt Accessions	Q13002	Gene names	GRIK2, GLUR6
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 2 precursor (Glutamate receptor 6) (GluR-6) (GluR6) (Excitatory amino acid receptor 4) (EAA4).

GRIK1_HUMAN
NC score	0.070159 (rank : 114)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	142	Target Neighborhood Hits	48	Shared Neighborhood Hits	23
SwissProt Accessions	P39086, Q13001, Q86SU9	Gene names	GRIK1, GLUR5
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 1 precursor (Glutamate receptor 5) (GluR-5) (GluR5) (Excitatory amino acid receptor 3) (EAA3).

NMDE4_MOUSE
NC score	0.070125 (rank : 115)	θ value	0.279714 (rank : 81)
Query Neighborhood Hits	142	Target Neighborhood Hits	158	Shared Neighborhood Hits	19
SwissProt Accessions	Q03391	Gene names	Grin2d
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 4 precursor (N-methyl D- aspartate receptor subtype 2D) (NR2D) (NMDAR2D).

GRIK1_MOUSE
NC score	0.069648 (rank : 116)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	142	Target Neighborhood Hits	46	Shared Neighborhood Hits	23
SwissProt Accessions	Q60934	Gene names	Grik1, Glur5
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 1 precursor (Glutamate receptor 5) (GluR-5) (GluR5).

SUSD3_HUMAN
NC score	0.068447 (rank : 117)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	142	Target Neighborhood Hits	32	Shared Neighborhood Hits	25
SwissProt Accessions	Q96L08, Q49AA6, Q6UXV7	Gene names	SUSD3, UNQ9387/PRO34275
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 3.

GRIK4_MOUSE
NC score	0.068348 (rank : 118)	θ value	2.36792 (rank : 99)
Query Neighborhood Hits	142	Target Neighborhood Hits	41	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BMF5	Gene names	Grik4
Domain Architecture	No domain graphic available
Description	Glutamate receptor, ionotropic kainate 4 precursor.

GRID2_HUMAN
NC score	0.067449 (rank : 119)	θ value	1.81305 (rank : 95)
Query Neighborhood Hits	142	Target Neighborhood Hits	48	Shared Neighborhood Hits	16
SwissProt Accessions	O43424	Gene names	GRID2, GLURD2
Domain Architecture
Description	Glutamate receptor delta-2 subunit precursor (GluR delta-2).

GUC2E_MOUSE
NC score	0.066121 (rank : 120)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	142	Target Neighborhood Hits	692	Shared Neighborhood Hits	12
SwissProt Accessions	P52785	Gene names	Gucy2e, Guc2e
Domain Architecture
Description	Guanylyl cyclase GC-E precursor (EC 4.6.1.2) (Guanylate cyclase 2E).

GUC2D_HUMAN
NC score	0.065952 (rank : 121)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	142	Target Neighborhood Hits	715	Shared Neighborhood Hits	13
SwissProt Accessions	Q02846, Q6LEA7	Gene names	GUCY2D, CORD6, GUC1A4, GUC2D, RETGC, RETGC1
Domain Architecture
Description	Retinal guanylyl cyclase 1 precursor (EC 4.6.1.2) (Guanylate cyclase 2D, retinal) (RETGC-1) (Rod outer segment membrane guanylate cyclase) (ROS-GC).

GRID2_MOUSE
NC score	0.065810 (rank : 122)	θ value	3.0926 (rank : 103)
Query Neighborhood Hits	142	Target Neighborhood Hits	44	Shared Neighborhood Hits	16
SwissProt Accessions	Q61625	Gene names	Grid2
Domain Architecture
Description	Glutamate receptor delta-2 subunit precursor (GluR delta-2).

GRIA4_MOUSE
NC score	0.065260 (rank : 123)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	142	Target Neighborhood Hits	44	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Z2W8	Gene names	Gria4, Glur4
Domain Architecture
Description	Glutamate receptor 4 precursor (GluR-4) (GluR4) (GluR-D) (Glutamate receptor ionotropic, AMPA 4) (AMPA-selective glutamate receptor 4).

GRIA4_HUMAN
NC score	0.065160 (rank : 124)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	142	Target Neighborhood Hits	45	Shared Neighborhood Hits	15
SwissProt Accessions	P48058	Gene names	GRIA4, GLUR4
Domain Architecture
Description	Glutamate receptor 4 precursor (GluR-4) (GluR4) (GluR-D) (Glutamate receptor ionotropic, AMPA 4) (AMPA-selective glutamate receptor 4).

GRIK3_HUMAN
NC score	0.062153 (rank : 125)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	142	Target Neighborhood Hits	41	Shared Neighborhood Hits	21
SwissProt Accessions	Q13003, Q13004, Q16136	Gene names	GRIK3, GLUR7
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 3 precursor (Glutamate receptor 7) (GluR-7) (GluR7) (Excitatory amino acid receptor 5) (EAA5).

NMDE2_MOUSE
NC score	0.058557 (rank : 126)	θ value	8.99809 (rank : 139)
Query Neighborhood Hits	142	Target Neighborhood Hits	64	Shared Neighborhood Hits	19
SwissProt Accessions	Q01097, Q9DCB2	Gene names	Grin2b
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 2 precursor (N-methyl D- aspartate receptor subtype 2B) (NR2B) (NMDAR2B).

GRIK5_MOUSE
NC score	0.057984 (rank : 127)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	142	Target Neighborhood Hits	47	Shared Neighborhood Hits	13
SwissProt Accessions	Q61626	Gene names	Grik5
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 5 precursor (Glutamate receptor KA-2) (KA2) (Glutamate receptor gamma-2) (GluR gamma-2).

GRIK5_HUMAN
NC score	0.057909 (rank : 128)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	142	Target Neighborhood Hits	44	Shared Neighborhood Hits	13
SwissProt Accessions	Q16478	Gene names	GRIK5, GRIK2
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 5 precursor (Glutamate receptor KA-2) (KA2) (Excitatory amino acid receptor 2) (EAA2).

GUC2C_HUMAN
NC score	0.057227 (rank : 129)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	142	Target Neighborhood Hits	624	Shared Neighborhood Hits	8
SwissProt Accessions	P25092	Gene names	GUCY2C, GUC2C, STAR
Domain Architecture
Description	Heat-stable enterotoxin receptor precursor (GC-C) (Intestinal guanylate cyclase) (EC 4.6.1.2) (STA receptor) (hSTAR).

GRID1_HUMAN
NC score	0.056664 (rank : 130)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	142	Target Neighborhood Hits	42	Shared Neighborhood Hits	15
SwissProt Accessions	Q9ULK0, Q8IXT3	Gene names	GRID1, KIAA1220
Domain Architecture
Description	Glutamate receptor delta-1 subunit precursor (GluR delta-1).

GRID1_MOUSE
NC score	0.056655 (rank : 131)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	142	Target Neighborhood Hits	42	Shared Neighborhood Hits	15
SwissProt Accessions	Q61627	Gene names	Grid1
Domain Architecture
Description	Glutamate receptor delta-1 subunit precursor (GluR delta-1).

MASP2_MOUSE
NC score	0.056380 (rank : 132)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	142	Target Neighborhood Hits	382	Shared Neighborhood Hits	44
SwissProt Accessions	Q91WP0, Q9QXA4, Q9QXD2, Q9QXD5, Q9Z338	Gene names	Masp2
Domain Architecture	No domain graphic available
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

NMDE2_HUMAN
NC score	0.054574 (rank : 133)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	142	Target Neighborhood Hits	65	Shared Neighborhood Hits	17
SwissProt Accessions	Q13224, Q12919, Q13220, Q13225, Q9UM56	Gene names	GRIN2B
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 2 precursor (N-methyl D- aspartate receptor subtype 2B) (NR2B) (NMDAR2B) (N-methyl-D-aspartate receptor subunit 3) (NR3) (hNR3).

ATF3_HUMAN
NC score	0.054351 (rank : 134)	θ value	1.06291 (rank : 85)
Query Neighborhood Hits	142	Target Neighborhood Hits	120	Shared Neighborhood Hits	8
SwissProt Accessions	P18847	Gene names	ATF3
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-3 (Activating transcription factor 3).

ATF3_MOUSE
NC score	0.054136 (rank : 135)	θ value	1.06291 (rank : 86)
Query Neighborhood Hits	142	Target Neighborhood Hits	120	Shared Neighborhood Hits	7
SwissProt Accessions	Q60765	Gene names	Atf3
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-3 (Activating transcription factor 3) (Transcription factor LRG-21).

NMDE3_MOUSE
NC score	0.053306 (rank : 136)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	142	Target Neighborhood Hits	86	Shared Neighborhood Hits	15
SwissProt Accessions	Q01098	Gene names	Grin2c
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 3 precursor (N-methyl D- aspartate receptor subtype 2C) (NR2C) (NMDAR2C).

NMDE3_HUMAN
NC score	0.052940 (rank : 137)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	142	Target Neighborhood Hits	110	Shared Neighborhood Hits	15
SwissProt Accessions	Q14957	Gene names	GRIN2C
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 3 precursor (N-methyl D- aspartate receptor subtype 2C) (NR2C) (NMDAR2C).

PERT_MOUSE
NC score	0.051287 (rank : 138)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	142	Target Neighborhood Hits	221	Shared Neighborhood Hits	41
SwissProt Accessions	P35419, Q8C8B1	Gene names	Tpo
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

NMD3A_HUMAN
NC score	0.051155 (rank : 139)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	142	Target Neighborhood Hits	58	Shared Neighborhood Hits	18
SwissProt Accessions	Q8TCU5, Q8TF29, Q8WXI6	Gene names	GRIN3A, KIAA1973
Domain Architecture	No domain graphic available
Description	Glutamate [NMDA] receptor subunit 3A precursor (N-methyl-D-aspartate receptor subtype NR3A) (NMDAR-L).

ADCY9_HUMAN
NC score	0.051089 (rank : 140)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	142	Target Neighborhood Hits	51	Shared Neighborhood Hits	6
SwissProt Accessions	O60503, O60273, Q4ZHT9, Q4ZIR5, Q9BWT4, Q9UGP2	Gene names	ADCY9, KIAA0520
Domain Architecture
Description	Adenylate cyclase type 9 (EC 4.6.1.1) (Adenylate cyclase type IX) (ATP pyrophosphate-lyase 9) (Adenylyl cyclase 9).

ADCY9_MOUSE
NC score	0.050969 (rank : 141)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	142	Target Neighborhood Hits	46	Shared Neighborhood Hits	6
SwissProt Accessions	P51830, Q61279	Gene names	Adcy9
Domain Architecture
Description	Adenylate cyclase type 9 (EC 4.6.1.1) (Adenylate cyclase type IX) (ATP pyrophosphate-lyase 9) (Adenylyl cyclase 9) (Adenylyl cyclase type 10) (ACTP10).

MASP2_HUMAN
NC score	0.050486 (rank : 142)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	142	Target Neighborhood Hits	364	Shared Neighborhood Hits	42
SwissProt Accessions	O00187, O75754, Q5TEQ5, Q5TER0, Q96QG4, Q9BZH0, Q9H498, Q9H499, Q9UBP3, Q9ULC7, Q9UMV3, Q9Y270	Gene names	MASP2
Domain Architecture
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

PAPOB_MOUSE
NC score	0.035523 (rank : 143)	θ value	1.81305 (rank : 96)
Query Neighborhood Hits	142	Target Neighborhood Hits	25	Shared Neighborhood Hits	6
SwissProt Accessions	Q9WVP6, Q9R1R3	Gene names	Papolb, Papt, Tpap
Domain Architecture
Description	Poly(A) polymerase beta (EC 2.7.7.19) (PAP beta) (Polynucleotide adenylyltransferase beta) (Testis-specific poly(A) polymerase).

PAPOA_MOUSE
NC score	0.030859 (rank : 144)	θ value	5.27518 (rank : 120)
Query Neighborhood Hits	142	Target Neighborhood Hits	115	Shared Neighborhood Hits	8
SwissProt Accessions	Q61183, Q61208, Q61209, Q8K4X2	Gene names	Papola, Pap, Plap
Domain Architecture
Description	Poly(A) polymerase alpha (EC 2.7.7.19) (PAP) (Polynucleotide adenylyltransferase).

PAPOB_HUMAN
NC score	0.029424 (rank : 145)	θ value	5.27518 (rank : 121)
Query Neighborhood Hits	142	Target Neighborhood Hits	25	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NRJ5, Q8NE14	Gene names	PAPOLB, PAPT
Domain Architecture
Description	Poly(A) polymerase beta (EC 2.7.7.19) (PAP beta) (Polynucleotide adenylyltransferase beta) (Testis-specific poly(A) polymerase).

PAPOA_HUMAN
NC score	0.028922 (rank : 146)	θ value	5.27518 (rank : 119)
Query Neighborhood Hits	142	Target Neighborhood Hits	75	Shared Neighborhood Hits	6
SwissProt Accessions	P51003, Q86SX4, Q86TV0, Q8IYF5, Q9BVU2	Gene names	PAPOLA, PAP
Domain Architecture	No domain graphic available
Description	Poly(A) polymerase alpha (EC 2.7.7.19) (PAP) (Polynucleotide adenylyltransferase alpha).

HAP1_HUMAN
NC score	0.026558 (rank : 147)	θ value	3.0926 (rank : 104)
Query Neighborhood Hits	142	Target Neighborhood Hits	606	Shared Neighborhood Hits	26
SwissProt Accessions	P54257, O75358, Q9H4G3, Q9HA98, Q9NY90	Gene names	HAP1, HLP1
Domain Architecture
Description	Huntingtin-associated protein 1 (HAP-1) (Neuroan 1).

ATCAY_MOUSE
NC score	0.021450 (rank : 148)	θ value	2.36792 (rank : 98)
Query Neighborhood Hits	142	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BHE3, Q3TR94	Gene names	Atcay
Domain Architecture
Description	Caytaxin.

EVPL_HUMAN
NC score	0.019705 (rank : 149)	θ value	1.38821 (rank : 90)
Query Neighborhood Hits	142	Target Neighborhood Hits	895	Shared Neighborhood Hits	26
SwissProt Accessions	Q92817	Gene names	EVPL
Domain Architecture
Description	Envoplakin (210 kDa paraneoplastic pemphigus antigen) (p210) (210 kDa cornified envelope precursor protein).

CT2NL_MOUSE
NC score	0.019628 (rank : 150)	θ value	5.27518 (rank : 114)
Query Neighborhood Hits	142	Target Neighborhood Hits	902	Shared Neighborhood Hits	25
SwissProt Accessions	Q99LJ0, Q6ZPR0, Q8BSV1	Gene names	Cttnbp2nl, Kiaa1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

HEM0_HUMAN
NC score	0.019035 (rank : 151)	θ value	3.0926 (rank : 105)
Query Neighborhood Hits	142	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	P22557, Q13735	Gene names	ALAS2, ALASE, ASB
Domain Architecture
Description	5-aminolevulinate synthase, erythroid-specific, mitochondrial precursor (EC 2.3.1.37) (5-aminolevulinic acid synthase) (Delta- aminolevulinate synthase) (Delta-ALA synthetase) (ALAS-E).

RTN3_HUMAN
NC score	0.017671 (rank : 152)	θ value	6.88961 (rank : 128)
Query Neighborhood Hits	142	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	O95197, Q496K2, Q7RTM8	Gene names	RTN3, NSPL2
Domain Architecture
Description	Reticulon-3 (Neuroendocrine-specific protein-like 2) (NSP-like protein II) (NSPLII).

CT2NL_HUMAN
NC score	0.017260 (rank : 153)	θ value	4.03905 (rank : 111)
Query Neighborhood Hits	142	Target Neighborhood Hits	1059	Shared Neighborhood Hits	26
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

HOME2_MOUSE
NC score	0.016151 (rank : 154)	θ value	3.0926 (rank : 106)
Query Neighborhood Hits	142	Target Neighborhood Hits	882	Shared Neighborhood Hits	30
SwissProt Accessions	Q9QWW1, O89025, Q9Z0E4	Gene names	Homer2, Vesl2
Domain Architecture
Description	Homer protein homolog 2 (Homer-2) (Cupidin) (VASP/Ena-related gene up- regulated during seizure and LTP 2) (Vesl-2).

RTN3_MOUSE
NC score	0.015492 (rank : 155)	θ value	8.99809 (rank : 141)
Query Neighborhood Hits	142	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ES97	Gene names	Rtn3
Domain Architecture
Description	Reticulon-3.

CCD46_HUMAN
NC score	0.015412 (rank : 156)	θ value	1.81305 (rank : 94)
Query Neighborhood Hits	142	Target Neighborhood Hits	1430	Shared Neighborhood Hits	32
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

SAS10_MOUSE
NC score	0.014455 (rank : 157)	θ value	6.88961 (rank : 129)
Query Neighborhood Hits	142	Target Neighborhood Hits	81	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JI13, Q3UL95, Q8R5C6, Q9JJ12	Gene names	Crlz1, Crl1, Sas10
Domain Architecture	No domain graphic available
Description	Something about silencing protein 10 (Disrupter of silencing SAS10) (Charged amino acid-rich leucine zipper 1) (Crl-1).

TRAK1_HUMAN
NC score	0.014031 (rank : 158)	θ value	6.88961 (rank : 130)
Query Neighborhood Hits	142	Target Neighborhood Hits	660	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UPV9, Q96B69	Gene names	TRAK1, KIAA1042, OIP106
Domain Architecture	No domain graphic available
Description	Trafficking kinesin-binding protein 1 (106 kDa O-GlcNAc transferase- interacting protein).

CP250_HUMAN
NC score	0.013798 (rank : 159)	θ value	1.06291 (rank : 87)
Query Neighborhood Hits	142	Target Neighborhood Hits	1805	Shared Neighborhood Hits	31
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

K1C14_MOUSE
NC score	0.013611 (rank : 160)	θ value	2.36792 (rank : 100)
Query Neighborhood Hits	142	Target Neighborhood Hits	501	Shared Neighborhood Hits	27
SwissProt Accessions	Q61781, Q91VQ4	Gene names	Krt14, Krt1-14
Domain Architecture
Description	Keratin, type I cytoskeletal 14 (Cytokeratin-14) (CK-14) (Keratin-14) (K14).

CCD21_HUMAN
NC score	0.013400 (rank : 161)	θ value	5.27518 (rank : 113)
Query Neighborhood Hits	142	Target Neighborhood Hits	1228	Shared Neighborhood Hits	30
SwissProt Accessions	Q6P2H3, Q5VY68, Q5VY70, Q9H6Q1, Q9H828, Q9UF52	Gene names	CCDC21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

MYH9_MOUSE
NC score	0.013158 (rank : 162)	θ value	5.27518 (rank : 118)
Query Neighborhood Hits	142	Target Neighborhood Hits	1829	Shared Neighborhood Hits	33
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

MYH9_HUMAN
NC score	0.013147 (rank : 163)	θ value	5.27518 (rank : 117)
Query Neighborhood Hits	142	Target Neighborhood Hits	1762	Shared Neighborhood Hits	32
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

MYH2_HUMAN
NC score	0.012618 (rank : 164)	θ value	6.88961 (rank : 126)
Query Neighborhood Hits	142	Target Neighborhood Hits	1491	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UKX2, Q14322, Q16229	Gene names	MYH2, MYHSA2
Domain Architecture
Description	Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy chain IIa) (MyHC-IIa).

TPR_HUMAN
NC score	0.012475 (rank : 165)	θ value	3.0926 (rank : 109)
Query Neighborhood Hits	142	Target Neighborhood Hits	1921	Shared Neighborhood Hits	31
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

HIP1_HUMAN
NC score	0.012426 (rank : 166)	θ value	6.88961 (rank : 125)
Query Neighborhood Hits	142	Target Neighborhood Hits	1016	Shared Neighborhood Hits	27
SwissProt Accessions	O00291, O00328, Q8TDL4	Gene names	HIP1
Domain Architecture
Description	Huntingtin-interacting protein 1 (HIP-I).

MYH1_MOUSE
NC score	0.012074 (rank : 167)	θ value	8.99809 (rank : 138)
Query Neighborhood Hits	142	Target Neighborhood Hits	1461	Shared Neighborhood Hits	32
SwissProt Accessions	Q5SX40	Gene names	Myh1
Domain Architecture	No domain graphic available
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1).

K1H4_HUMAN
NC score	0.011581 (rank : 168)	θ value	3.0926 (rank : 107)
Query Neighborhood Hits	142	Target Neighborhood Hits	476	Shared Neighborhood Hits	22
SwissProt Accessions	O76011	Gene names	KRTHA4, HHA4, HKA4
Domain Architecture
Description	Keratin, type I cuticular Ha4 (Hair keratin, type I Ha4).

CP135_MOUSE
NC score	0.011431 (rank : 169)	θ value	8.99809 (rank : 131)
Query Neighborhood Hits	142	Target Neighborhood Hits	1278	Shared Neighborhood Hits	29
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

K1C14_HUMAN
NC score	0.011376 (rank : 170)	θ value	8.99809 (rank : 132)
Query Neighborhood Hits	142	Target Neighborhood Hits	491	Shared Neighborhood Hits	25
SwissProt Accessions	P02533, Q14715, Q53XY3, Q9BUE3, Q9UBN2, Q9UBN3, Q9UCY4	Gene names	KRT14
Domain Architecture
Description	Keratin, type I cytoskeletal 14 (Cytokeratin-14) (CK-14) (Keratin-14) (K14).

MYH10_HUMAN
NC score	0.011122 (rank : 171)	θ value	8.99809 (rank : 135)
Query Neighborhood Hits	142	Target Neighborhood Hits	1620	Shared Neighborhood Hits	31
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH10_MOUSE
NC score	0.010999 (rank : 172)	θ value	8.99809 (rank : 136)
Query Neighborhood Hits	142	Target Neighborhood Hits	1612	Shared Neighborhood Hits	31
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH1_HUMAN
NC score	0.010975 (rank : 173)	θ value	8.99809 (rank : 137)
Query Neighborhood Hits	142	Target Neighborhood Hits	1478	Shared Neighborhood Hits	31
SwissProt Accessions	P12882, Q9Y622	Gene names	MYH1
Domain Architecture
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1) (Myosin heavy chain IIx/d) (MyHC-IIx/d).

ANR26_MOUSE
NC score	0.010250 (rank : 174)	θ value	4.03905 (rank : 110)
Query Neighborhood Hits	142	Target Neighborhood Hits	1554	Shared Neighborhood Hits	33
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

TROAP_HUMAN
NC score	0.010210 (rank : 175)	θ value	8.99809 (rank : 142)
Query Neighborhood Hits	142	Target Neighborhood Hits	258	Shared Neighborhood Hits	3
SwissProt Accessions	Q12815	Gene names	TROAP
Domain Architecture	No domain graphic available
Description	Trophinin-associated protein (Tastin) (Trophinin-assisting protein).

K1C16_HUMAN
NC score	0.009127 (rank : 176)	θ value	8.99809 (rank : 133)
Query Neighborhood Hits	142	Target Neighborhood Hits	440	Shared Neighborhood Hits	23
SwissProt Accessions	P08779, P30654, Q16402, Q9UBG8	Gene names	KRT16, KRT16A
Domain Architecture
Description	Keratin, type I cytoskeletal 16 (Cytokeratin-16) (CK-16) (Keratin-16) (K16).

GEMI5_MOUSE
NC score	0.009118 (rank : 177)	θ value	6.88961 (rank : 124)
Query Neighborhood Hits	142	Target Neighborhood Hits	424	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BX17	Gene names	Gemin5
Domain Architecture
Description	Gem-associated protein 5 (Gemin5).

TRI63_HUMAN
NC score	0.008644 (rank : 178)	θ value	5.27518 (rank : 122)
Query Neighborhood Hits	142	Target Neighborhood Hits	298	Shared Neighborhood Hits	15
SwissProt Accessions	Q969Q1, Q5T2I1, Q96BD3, Q96KD9, Q9BYV4	Gene names	TRIM63, IRF, MURF1, RNF28, SMRZ
Domain Architecture
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (RING finger protein 28) (Striated muscle RING zinc finger protein) (Iris RING finger protein).

ROCK2_HUMAN
NC score	0.007883 (rank : 179)	θ value	3.0926 (rank : 108)
Query Neighborhood Hits	142	Target Neighborhood Hits	2073	Shared Neighborhood Hits	37
SwissProt Accessions	O75116, Q9UQN5	Gene names	ROCK2, KIAA0619
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2).

CALI_HUMAN
NC score	0.007627 (rank : 180)	θ value	6.88961 (rank : 123)
Query Neighborhood Hits	142	Target Neighborhood Hits	183	Shared Neighborhood Hits	4
SwissProt Accessions	Q13939, Q9BXG7	Gene names	CCIN
Domain Architecture
Description	Calicin.

ROCK2_MOUSE
NC score	0.006813 (rank : 181)	θ value	6.88961 (rank : 127)
Query Neighborhood Hits	142	Target Neighborhood Hits	2072	Shared Neighborhood Hits	37
SwissProt Accessions	P70336, Q8BR64, Q8CBR0	Gene names	Rock2
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2).

KI13A_MOUSE
NC score	0.006518 (rank : 182)	θ value	5.27518 (rank : 116)
Query Neighborhood Hits	142	Target Neighborhood Hits	395	Shared Neighborhood Hits	21
SwissProt Accessions	Q9EQW7, O35062	Gene names	Kif13a
Domain Architecture
Description	Kinesin-like protein KIF13A.

ASPP1_MOUSE
NC score	0.005403 (rank : 183)	θ value	5.27518 (rank : 112)
Query Neighborhood Hits	142	Target Neighborhood Hits	1244	Shared Neighborhood Hits	25
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

MASTL_HUMAN
NC score	0.001241 (rank : 184)	θ value	8.99809 (rank : 134)
Query Neighborhood Hits	142	Target Neighborhood Hits	894	Shared Neighborhood Hits	12
SwissProt Accessions	Q96GX5, Q5T8D5, Q5T8D7, Q8NCD6, Q96SJ5	Gene names	MASTL, THC2
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase-like (EC 2.7.11.1).

PCDBC_HUMAN
NC score	0.000156 (rank : 185)	θ value	8.99809 (rank : 140)
Query Neighborhood Hits	142	Target Neighborhood Hits	157	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y5F1	Gene names	PCDHB12
Domain Architecture
Description	Protocadherin beta 12 precursor (PCDH-beta12).