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Network neighborhood for query Sequence : GRIA2_HUMAN

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GRIA2_HUMAN
SwissProt Accessions	P42262, Q96FP6	Gene names	GRIA2, GLUR2
Domain Architecture
Description	Glutamate receptor 2 precursor (GluR-2) (GluR-B) (GluR-K2) (Glutamate receptor ionotropic, AMPA 2) (AMPA-selective glutamate receptor 2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

GRIA1_HUMAN
θ value	0 (rank : 1)	NC score	0.998798 (rank : 3)
Query Neighborhood Hits	47	Target Neighborhood Hits	45	Shared Neighborhood Hits	42
SwissProt Accessions	P42261	Gene names	GRIA1, GLUH1, GLUR1
Domain Architecture
Description	Glutamate receptor 1 precursor (GluR-1) (GluR-A) (GluR-K1) (Glutamate receptor ionotropic, AMPA 1) (AMPA-selective glutamate receptor 1).

GRIA1_MOUSE
θ value	0 (rank : 2)	NC score	0.998710 (rank : 4)
Query Neighborhood Hits	47	Target Neighborhood Hits	46	Shared Neighborhood Hits	42
SwissProt Accessions	P23818	Gene names	Gria1, Glur1
Domain Architecture
Description	Glutamate receptor 1 precursor (GluR-1) (GluR-A) (GluR-K1) (Glutamate receptor ionotropic, AMPA 1) (AMPA-selective glutamate receptor 1).

GRIA2_HUMAN
θ value	0 (rank : 3)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	47	Target Neighborhood Hits	47	Shared Neighborhood Hits	47
SwissProt Accessions	P42262, Q96FP6	Gene names	GRIA2, GLUR2
Domain Architecture
Description	Glutamate receptor 2 precursor (GluR-2) (GluR-B) (GluR-K2) (Glutamate receptor ionotropic, AMPA 2) (AMPA-selective glutamate receptor 2).

GRIA2_MOUSE
θ value	0 (rank : 4)	NC score	0.999960 (rank : 2)
Query Neighborhood Hits	47	Target Neighborhood Hits	47	Shared Neighborhood Hits	47
SwissProt Accessions	P23819, Q61604, Q61605, Q8BG69, Q8BXU3, Q9D6D3	Gene names	Gria2, Glur2
Domain Architecture
Description	Glutamate receptor 2 precursor (GluR-2) (GluR-B) (GluR-K2) (Glutamate receptor ionotropic, AMPA 2) (AMPA-selective glutamate receptor 2).

GRIA3_HUMAN
θ value	0 (rank : 5)	NC score	0.998632 (rank : 6)
Query Neighborhood Hits	47	Target Neighborhood Hits	40	Shared Neighborhood Hits	35
SwissProt Accessions	P42263, Q4VXD5, Q4VXD6, Q9HDA0, Q9HDA1, Q9HDA2	Gene names	GRIA3, GLUR3, GLURC
Domain Architecture
Description	Glutamate receptor 3 precursor (GluR-3) (GluR-C) (GluR-K3) (Glutamate receptor ionotropic, AMPA 3) (AMPA-selective glutamate receptor 3).

GRIA3_MOUSE
θ value	0 (rank : 6)	NC score	0.998705 (rank : 5)
Query Neighborhood Hits	47	Target Neighborhood Hits	39	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Z2W9, Q5DTJ0	Gene names	Gria3, Glur3, Kiaa4184
Domain Architecture	No domain graphic available
Description	Glutamate receptor 3 precursor (GluR-3) (GluR-C) (GluR-K3) (Glutamate receptor ionotropic, AMPA 3) (AMPA-selective glutamate receptor 3).

GRIA4_HUMAN
θ value	0 (rank : 7)	NC score	0.998098 (rank : 8)
Query Neighborhood Hits	47	Target Neighborhood Hits	45	Shared Neighborhood Hits	37
SwissProt Accessions	P48058	Gene names	GRIA4, GLUR4
Domain Architecture
Description	Glutamate receptor 4 precursor (GluR-4) (GluR4) (GluR-D) (Glutamate receptor ionotropic, AMPA 4) (AMPA-selective glutamate receptor 4).

GRIA4_MOUSE
θ value	0 (rank : 8)	NC score	0.998167 (rank : 7)
Query Neighborhood Hits	47	Target Neighborhood Hits	44	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Z2W8	Gene names	Gria4, Glur4
Domain Architecture
Description	Glutamate receptor 4 precursor (GluR-4) (GluR4) (GluR-D) (Glutamate receptor ionotropic, AMPA 4) (AMPA-selective glutamate receptor 4).

GRIK2_HUMAN
θ value	2.7506e-174 (rank : 9)	NC score	0.978913 (rank : 10)
Query Neighborhood Hits	47	Target Neighborhood Hits	50	Shared Neighborhood Hits	33
SwissProt Accessions	Q13002	Gene names	GRIK2, GLUR6
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 2 precursor (Glutamate receptor 6) (GluR-6) (GluR6) (Excitatory amino acid receptor 4) (EAA4).

GRIK3_HUMAN
θ value	2.58046e-164 (rank : 10)	NC score	0.979808 (rank : 9)
Query Neighborhood Hits	47	Target Neighborhood Hits	41	Shared Neighborhood Hits	33
SwissProt Accessions	Q13003, Q13004, Q16136	Gene names	GRIK3, GLUR7
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 3 precursor (Glutamate receptor 7) (GluR-7) (GluR7) (Excitatory amino acid receptor 5) (EAA5).

GRIK1_HUMAN
θ value	4.11978e-162 (rank : 11)	NC score	0.977709 (rank : 11)
Query Neighborhood Hits	47	Target Neighborhood Hits	48	Shared Neighborhood Hits	33
SwissProt Accessions	P39086, Q13001, Q86SU9	Gene names	GRIK1, GLUR5
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 1 precursor (Glutamate receptor 5) (GluR-5) (GluR5) (Excitatory amino acid receptor 3) (EAA3).

GRIK5_MOUSE
θ value	1.12714e-143 (rank : 12)	NC score	0.974362 (rank : 14)
Query Neighborhood Hits	47	Target Neighborhood Hits	47	Shared Neighborhood Hits	33
SwissProt Accessions	Q61626	Gene names	Grik5
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 5 precursor (Glutamate receptor KA-2) (KA2) (Glutamate receptor gamma-2) (GluR gamma-2).

GRIK4_HUMAN
θ value	1.92261e-143 (rank : 13)	NC score	0.974440 (rank : 13)
Query Neighborhood Hits	47	Target Neighborhood Hits	42	Shared Neighborhood Hits	35
SwissProt Accessions	Q16099	Gene names	GRIK4, GRIK
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 4 precursor (Glutamate receptor KA-1) (KA1) (Excitatory amino acid receptor 1) (EAA1).

GRIK4_MOUSE
θ value	1.92261e-143 (rank : 14)	NC score	0.974107 (rank : 16)
Query Neighborhood Hits	47	Target Neighborhood Hits	41	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BMF5	Gene names	Grik4
Domain Architecture	No domain graphic available
Description	Glutamate receptor, ionotropic kainate 4 precursor.

GRIK5_HUMAN
θ value	8.0776e-142 (rank : 15)	NC score	0.974221 (rank : 15)
Query Neighborhood Hits	47	Target Neighborhood Hits	44	Shared Neighborhood Hits	33
SwissProt Accessions	Q16478	Gene names	GRIK5, GRIK2
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 5 precursor (Glutamate receptor KA-2) (KA2) (Excitatory amino acid receptor 2) (EAA2).

GRIK1_MOUSE
θ value	1.38103e-133 (rank : 16)	NC score	0.975845 (rank : 12)
Query Neighborhood Hits	47	Target Neighborhood Hits	46	Shared Neighborhood Hits	33
SwissProt Accessions	Q60934	Gene names	Grik1, Glur5
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 1 precursor (Glutamate receptor 5) (GluR-5) (GluR5).

GRID2_MOUSE
θ value	2.38316e-93 (rank : 17)	NC score	0.947759 (rank : 17)
Query Neighborhood Hits	47	Target Neighborhood Hits	44	Shared Neighborhood Hits	35
SwissProt Accessions	Q61625	Gene names	Grid2
Domain Architecture
Description	Glutamate receptor delta-2 subunit precursor (GluR delta-2).

GRID2_HUMAN
θ value	4.06505e-93 (rank : 18)	NC score	0.947553 (rank : 18)
Query Neighborhood Hits	47	Target Neighborhood Hits	48	Shared Neighborhood Hits	35
SwissProt Accessions	O43424	Gene names	GRID2, GLURD2
Domain Architecture
Description	Glutamate receptor delta-2 subunit precursor (GluR delta-2).

GRID1_MOUSE
θ value	7.66637e-92 (rank : 19)	NC score	0.946460 (rank : 19)
Query Neighborhood Hits	47	Target Neighborhood Hits	42	Shared Neighborhood Hits	33
SwissProt Accessions	Q61627	Gene names	Grid1
Domain Architecture
Description	Glutamate receptor delta-1 subunit precursor (GluR delta-1).

GRID1_HUMAN
θ value	1.30768e-91 (rank : 20)	NC score	0.946306 (rank : 20)
Query Neighborhood Hits	47	Target Neighborhood Hits	42	Shared Neighborhood Hits	33
SwissProt Accessions	Q9ULK0, Q8IXT3	Gene names	GRID1, KIAA1220
Domain Architecture
Description	Glutamate receptor delta-1 subunit precursor (GluR delta-1).

NMDZ1_MOUSE
θ value	3.71096e-62 (rank : 21)	NC score	0.899060 (rank : 22)
Query Neighborhood Hits	47	Target Neighborhood Hits	76	Shared Neighborhood Hits	33
SwissProt Accessions	P35438, Q8CFS4	Gene names	Grin1, Glurz1
Domain Architecture
Description	Glutamate [NMDA] receptor subunit zeta 1 precursor (N-methyl-D- aspartate receptor subunit NR1).

NMDZ1_HUMAN
θ value	4.84666e-62 (rank : 22)	NC score	0.899164 (rank : 21)
Query Neighborhood Hits	47	Target Neighborhood Hits	77	Shared Neighborhood Hits	33
SwissProt Accessions	Q05586, P35437, Q12867, Q12868	Gene names	GRIN1, NMDAR1
Domain Architecture
Description	Glutamate [NMDA] receptor subunit zeta 1 precursor (N-methyl-D- aspartate receptor subunit NR1).

NMDE2_MOUSE
θ value	2.41655e-45 (rank : 23)	NC score	0.829676 (rank : 30)
Query Neighborhood Hits	47	Target Neighborhood Hits	64	Shared Neighborhood Hits	35
SwissProt Accessions	Q01097, Q9DCB2	Gene names	Grin2b
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 2 precursor (N-methyl D- aspartate receptor subtype 2B) (NR2B) (NMDAR2B).

NMDE2_HUMAN
θ value	3.15612e-45 (rank : 24)	NC score	0.829526 (rank : 31)
Query Neighborhood Hits	47	Target Neighborhood Hits	65	Shared Neighborhood Hits	33
SwissProt Accessions	Q13224, Q12919, Q13220, Q13225, Q9UM56	Gene names	GRIN2B
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 2 precursor (N-methyl D- aspartate receptor subtype 2B) (NR2B) (NMDAR2B) (N-methyl-D-aspartate receptor subunit 3) (NR3) (hNR3).

NMDE3_MOUSE
θ value	2.95404e-43 (rank : 25)	NC score	0.831727 (rank : 28)
Query Neighborhood Hits	47	Target Neighborhood Hits	86	Shared Neighborhood Hits	33
SwissProt Accessions	Q01098	Gene names	Grin2c
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 3 precursor (N-methyl D- aspartate receptor subtype 2C) (NR2C) (NMDAR2C).

NMDE4_HUMAN
θ value	1.46607e-42 (rank : 26)	NC score	0.834883 (rank : 26)
Query Neighborhood Hits	47	Target Neighborhood Hits	133	Shared Neighborhood Hits	35
SwissProt Accessions	O15399	Gene names	GRIN2D
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 4 precursor (N-methyl D- aspartate receptor subtype 2D) (NR2D) (NMDAR2D) (EB11).

NMDE4_MOUSE
θ value	1.46607e-42 (rank : 27)	NC score	0.832645 (rank : 27)
Query Neighborhood Hits	47	Target Neighborhood Hits	158	Shared Neighborhood Hits	35
SwissProt Accessions	Q03391	Gene names	Grin2d
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 4 precursor (N-methyl D- aspartate receptor subtype 2D) (NR2D) (NMDAR2D).

NMDE3_HUMAN
θ value	1.91475e-42 (rank : 28)	NC score	0.829960 (rank : 29)
Query Neighborhood Hits	47	Target Neighborhood Hits	110	Shared Neighborhood Hits	33
SwissProt Accessions	Q14957	Gene names	GRIN2C
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 3 precursor (N-methyl D- aspartate receptor subtype 2C) (NR2C) (NMDAR2C).

NMDE1_HUMAN
θ value	2.50074e-42 (rank : 29)	NC score	0.825165 (rank : 33)
Query Neighborhood Hits	47	Target Neighborhood Hits	81	Shared Neighborhood Hits	33
SwissProt Accessions	Q12879, O00669	Gene names	GRIN2A
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 1 precursor (N-methyl D- aspartate receptor subtype 2A) (NR2A) (NMDAR2A) (hNR2A).

NMDE1_MOUSE
θ value	2.50074e-42 (rank : 30)	NC score	0.825307 (rank : 32)
Query Neighborhood Hits	47	Target Neighborhood Hits	84	Shared Neighborhood Hits	33
SwissProt Accessions	P35436	Gene names	Grin2a
Domain Architecture	No domain graphic available
Description	Glutamate [NMDA] receptor subunit epsilon 1 precursor (N-methyl D- aspartate receptor subtype 2A) (NR2A) (NMDAR2A).

NMD3A_HUMAN
θ value	1.42001e-37 (rank : 31)	NC score	0.858111 (rank : 23)
Query Neighborhood Hits	47	Target Neighborhood Hits	58	Shared Neighborhood Hits	33
SwissProt Accessions	Q8TCU5, Q8TF29, Q8WXI6	Gene names	GRIN3A, KIAA1973
Domain Architecture	No domain graphic available
Description	Glutamate [NMDA] receptor subunit 3A precursor (N-methyl-D-aspartate receptor subtype NR3A) (NMDAR-L).

NMD3B_HUMAN
θ value	2.50655e-34 (rank : 32)	NC score	0.853175 (rank : 24)
Query Neighborhood Hits	47	Target Neighborhood Hits	55	Shared Neighborhood Hits	33
SwissProt Accessions	O60391, Q5EAK7, Q7RTW9	Gene names	GRIN3B
Domain Architecture	No domain graphic available
Description	Glutamate [NMDA] receptor subunit 3B precursor (N-methyl-D-aspartate receptor subtype NR3B) (NR3B) (NMDAR3B).

NMD3B_MOUSE
θ value	2.12192e-33 (rank : 33)	NC score	0.850618 (rank : 25)
Query Neighborhood Hits	47	Target Neighborhood Hits	51	Shared Neighborhood Hits	33
SwissProt Accessions	Q91ZU9, Q8VHV0	Gene names	Grin3b
Domain Architecture	No domain graphic available
Description	Glutamate [NMDA] receptor subunit 3B precursor (N-methyl-D-aspartate receptor subunit NR3B) (NR3B) (NMDAR3B) (NMDA receptor NR4) (Nr4).

GABR1_HUMAN
θ value	0.00665767 (rank : 34)	NC score	0.089487 (rank : 34)
Query Neighborhood Hits	47	Target Neighborhood Hits	142	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UBS5, O95375, O95468, O95975, O96022, Q86W60, Q9UQQ0	Gene names	GABBR1, GPRC3A
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 1 precursor (GABA-B receptor 1) (GABA-B-R1) (Gb1).

GABR1_MOUSE
θ value	0.00665767 (rank : 35)	NC score	0.089274 (rank : 35)
Query Neighborhood Hits	47	Target Neighborhood Hits	139	Shared Neighborhood Hits	15
SwissProt Accessions	Q9WV18, Q9WU48, Q9WV15, Q9WV16, Q9WV17	Gene names	Gabbr1
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 1 precursor (GABA-B receptor 1) (GABA-B-R1) (Gb1).

DDX48_HUMAN
θ value	1.06291 (rank : 36)	NC score	0.012589 (rank : 44)
Query Neighborhood Hits	47	Target Neighborhood Hits	102	Shared Neighborhood Hits	10
SwissProt Accessions	P38919, Q15033, Q96A18	Gene names	DDX48, EIF4A3, KIAA0111
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48) (Eukaryotic initiation factor 4A-like NUK-34) (Nuclear matrix protein 265) (hNMP 265) (Eukaryotic translation initiation factor 4A isoform 3).

DDX48_MOUSE
θ value	1.06291 (rank : 37)	NC score	0.012610 (rank : 43)
Query Neighborhood Hits	47	Target Neighborhood Hits	102	Shared Neighborhood Hits	10
SwissProt Accessions	Q91VC3	Gene names	Ddx48
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48).

PEPD_MOUSE
θ value	2.36792 (rank : 38)	NC score	0.016972 (rank : 37)
Query Neighborhood Hits	47	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q11136, P97735, Q3TH86, Q9CWK4	Gene names	Pepd, Pep4
Domain Architecture
Description	Xaa-Pro dipeptidase (EC 3.4.13.9) (X-Pro dipeptidase) (Proline dipeptidase) (Prolidase) (Imidodipeptidase) (Peptidase 4).

HELC1_HUMAN
θ value	3.0926 (rank : 39)	NC score	0.016326 (rank : 38)
Query Neighborhood Hits	47	Target Neighborhood Hits	71	Shared Neighborhood Hits	5
SwissProt Accessions	Q8N3C0, O43738, Q9H1I9, Q9NTR0	Gene names	ASCC3, HELIC1
Domain Architecture	No domain graphic available
Description	Activating signal cointegrator 1 complex subunit 3 (EC 3.6.1.-) (ASC-1 complex subunit p200) (Trip4 complex subunit p200) (Helicase, ATP binding 1).

IF4A1_HUMAN
θ value	3.0926 (rank : 40)	NC score	0.016005 (rank : 39)
Query Neighborhood Hits	47	Target Neighborhood Hits	106	Shared Neighborhood Hits	12
SwissProt Accessions	P60842, P04765, Q5U018, Q61516	Gene names	EIF4A1, DDX2A, EIF4A
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

IF4A1_MOUSE
θ value	3.0926 (rank : 41)	NC score	0.016005 (rank : 40)
Query Neighborhood Hits	47	Target Neighborhood Hits	106	Shared Neighborhood Hits	12
SwissProt Accessions	P60843, P04765, Q61516	Gene names	Eif4a1, Ddx2a, Eif4a
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

IF4A2_HUMAN
θ value	4.03905 (rank : 42)	NC score	0.014268 (rank : 41)
Query Neighborhood Hits	47	Target Neighborhood Hits	102	Shared Neighborhood Hits	12
SwissProt Accessions	Q14240, Q96B90, Q96EA8	Gene names	EIF4A2, DDX2B
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

IF4A2_MOUSE
θ value	4.03905 (rank : 43)	NC score	0.014268 (rank : 42)
Query Neighborhood Hits	47	Target Neighborhood Hits	102	Shared Neighborhood Hits	12
SwissProt Accessions	P10630, Q61513, Q61514	Gene names	Eif4a2, Ddx2b
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

SMYD2_HUMAN
θ value	5.27518 (rank : 44)	NC score	0.007897 (rank : 45)
Query Neighborhood Hits	47	Target Neighborhood Hits	37	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NRG4, Q4V765, Q5VSH9	Gene names	SMYD2
Domain Architecture
Description	SET and MYND domain-containing protein 2 (HSKM-B).

SEPT5_HUMAN
θ value	8.99809 (rank : 45)	NC score	0.002327 (rank : 48)
Query Neighborhood Hits	47	Target Neighborhood Hits	44	Shared Neighborhood Hits	3
SwissProt Accessions	Q99719, O15251	Gene names	SEPT5, PNUTL1
Domain Architecture
Description	Septin-5 (Peanut-like protein 1) (Cell division control-related protein 1) (CDCrel-1).

TR150_HUMAN
θ value	8.99809 (rank : 46)	NC score	0.006891 (rank : 46)
Query Neighborhood Hits	47	Target Neighborhood Hits	313	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y2W1, Q5VTK6	Gene names	THRAP3, TRAP150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

TR150_MOUSE
θ value	8.99809 (rank : 47)	NC score	0.005118 (rank : 47)
Query Neighborhood Hits	47	Target Neighborhood Hits	468	Shared Neighborhood Hits	4
SwissProt Accessions	Q569Z6	Gene names	Thrap3, Trap150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

ERB1_HUMAN
θ value	θ > 10 (rank : 48)	NC score	0.052377 (rank : 36)
Query Neighborhood Hits	47	Target Neighborhood Hits	23	Shared Neighborhood Hits	8
SwissProt Accessions	P60509	Gene names
Domain Architecture	No domain graphic available
Description	HERV-R(b)_3p24.3 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (HERV-R(b) Env protein) [Includes: Surface protein domain (SU); Transmembrane protein domain (TM)].

Hits sorted by NC score

GRIA2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 3)
Query Neighborhood Hits	47	Target Neighborhood Hits	47	Shared Neighborhood Hits	47
SwissProt Accessions	P42262, Q96FP6	Gene names	GRIA2, GLUR2
Domain Architecture
Description	Glutamate receptor 2 precursor (GluR-2) (GluR-B) (GluR-K2) (Glutamate receptor ionotropic, AMPA 2) (AMPA-selective glutamate receptor 2).

GRIA2_MOUSE
NC score	0.999960 (rank : 2)	θ value	0 (rank : 4)
Query Neighborhood Hits	47	Target Neighborhood Hits	47	Shared Neighborhood Hits	47
SwissProt Accessions	P23819, Q61604, Q61605, Q8BG69, Q8BXU3, Q9D6D3	Gene names	Gria2, Glur2
Domain Architecture
Description	Glutamate receptor 2 precursor (GluR-2) (GluR-B) (GluR-K2) (Glutamate receptor ionotropic, AMPA 2) (AMPA-selective glutamate receptor 2).

GRIA1_HUMAN
NC score	0.998798 (rank : 3)	θ value	0 (rank : 1)
Query Neighborhood Hits	47	Target Neighborhood Hits	45	Shared Neighborhood Hits	42
SwissProt Accessions	P42261	Gene names	GRIA1, GLUH1, GLUR1
Domain Architecture
Description	Glutamate receptor 1 precursor (GluR-1) (GluR-A) (GluR-K1) (Glutamate receptor ionotropic, AMPA 1) (AMPA-selective glutamate receptor 1).

GRIA1_MOUSE
NC score	0.998710 (rank : 4)	θ value	0 (rank : 2)
Query Neighborhood Hits	47	Target Neighborhood Hits	46	Shared Neighborhood Hits	42
SwissProt Accessions	P23818	Gene names	Gria1, Glur1
Domain Architecture
Description	Glutamate receptor 1 precursor (GluR-1) (GluR-A) (GluR-K1) (Glutamate receptor ionotropic, AMPA 1) (AMPA-selective glutamate receptor 1).

GRIA3_MOUSE
NC score	0.998705 (rank : 5)	θ value	0 (rank : 6)
Query Neighborhood Hits	47	Target Neighborhood Hits	39	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Z2W9, Q5DTJ0	Gene names	Gria3, Glur3, Kiaa4184
Domain Architecture	No domain graphic available
Description	Glutamate receptor 3 precursor (GluR-3) (GluR-C) (GluR-K3) (Glutamate receptor ionotropic, AMPA 3) (AMPA-selective glutamate receptor 3).

GRIA3_HUMAN
NC score	0.998632 (rank : 6)	θ value	0 (rank : 5)
Query Neighborhood Hits	47	Target Neighborhood Hits	40	Shared Neighborhood Hits	35
SwissProt Accessions	P42263, Q4VXD5, Q4VXD6, Q9HDA0, Q9HDA1, Q9HDA2	Gene names	GRIA3, GLUR3, GLURC
Domain Architecture
Description	Glutamate receptor 3 precursor (GluR-3) (GluR-C) (GluR-K3) (Glutamate receptor ionotropic, AMPA 3) (AMPA-selective glutamate receptor 3).

GRIA4_MOUSE
NC score	0.998167 (rank : 7)	θ value	0 (rank : 8)
Query Neighborhood Hits	47	Target Neighborhood Hits	44	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Z2W8	Gene names	Gria4, Glur4
Domain Architecture
Description	Glutamate receptor 4 precursor (GluR-4) (GluR4) (GluR-D) (Glutamate receptor ionotropic, AMPA 4) (AMPA-selective glutamate receptor 4).

GRIA4_HUMAN
NC score	0.998098 (rank : 8)	θ value	0 (rank : 7)
Query Neighborhood Hits	47	Target Neighborhood Hits	45	Shared Neighborhood Hits	37
SwissProt Accessions	P48058	Gene names	GRIA4, GLUR4
Domain Architecture
Description	Glutamate receptor 4 precursor (GluR-4) (GluR4) (GluR-D) (Glutamate receptor ionotropic, AMPA 4) (AMPA-selective glutamate receptor 4).

GRIK3_HUMAN
NC score	0.979808 (rank : 9)	θ value	2.58046e-164 (rank : 10)
Query Neighborhood Hits	47	Target Neighborhood Hits	41	Shared Neighborhood Hits	33
SwissProt Accessions	Q13003, Q13004, Q16136	Gene names	GRIK3, GLUR7
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 3 precursor (Glutamate receptor 7) (GluR-7) (GluR7) (Excitatory amino acid receptor 5) (EAA5).

GRIK2_HUMAN
NC score	0.978913 (rank : 10)	θ value	2.7506e-174 (rank : 9)
Query Neighborhood Hits	47	Target Neighborhood Hits	50	Shared Neighborhood Hits	33
SwissProt Accessions	Q13002	Gene names	GRIK2, GLUR6
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 2 precursor (Glutamate receptor 6) (GluR-6) (GluR6) (Excitatory amino acid receptor 4) (EAA4).

GRIK1_HUMAN
NC score	0.977709 (rank : 11)	θ value	4.11978e-162 (rank : 11)
Query Neighborhood Hits	47	Target Neighborhood Hits	48	Shared Neighborhood Hits	33
SwissProt Accessions	P39086, Q13001, Q86SU9	Gene names	GRIK1, GLUR5
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 1 precursor (Glutamate receptor 5) (GluR-5) (GluR5) (Excitatory amino acid receptor 3) (EAA3).

GRIK1_MOUSE
NC score	0.975845 (rank : 12)	θ value	1.38103e-133 (rank : 16)
Query Neighborhood Hits	47	Target Neighborhood Hits	46	Shared Neighborhood Hits	33
SwissProt Accessions	Q60934	Gene names	Grik1, Glur5
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 1 precursor (Glutamate receptor 5) (GluR-5) (GluR5).

GRIK4_HUMAN
NC score	0.974440 (rank : 13)	θ value	1.92261e-143 (rank : 13)
Query Neighborhood Hits	47	Target Neighborhood Hits	42	Shared Neighborhood Hits	35
SwissProt Accessions	Q16099	Gene names	GRIK4, GRIK
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 4 precursor (Glutamate receptor KA-1) (KA1) (Excitatory amino acid receptor 1) (EAA1).

GRIK5_MOUSE
NC score	0.974362 (rank : 14)	θ value	1.12714e-143 (rank : 12)
Query Neighborhood Hits	47	Target Neighborhood Hits	47	Shared Neighborhood Hits	33
SwissProt Accessions	Q61626	Gene names	Grik5
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 5 precursor (Glutamate receptor KA-2) (KA2) (Glutamate receptor gamma-2) (GluR gamma-2).

GRIK5_HUMAN
NC score	0.974221 (rank : 15)	θ value	8.0776e-142 (rank : 15)
Query Neighborhood Hits	47	Target Neighborhood Hits	44	Shared Neighborhood Hits	33
SwissProt Accessions	Q16478	Gene names	GRIK5, GRIK2
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 5 precursor (Glutamate receptor KA-2) (KA2) (Excitatory amino acid receptor 2) (EAA2).

GRIK4_MOUSE
NC score	0.974107 (rank : 16)	θ value	1.92261e-143 (rank : 14)
Query Neighborhood Hits	47	Target Neighborhood Hits	41	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BMF5	Gene names	Grik4
Domain Architecture	No domain graphic available
Description	Glutamate receptor, ionotropic kainate 4 precursor.

GRID2_MOUSE
NC score	0.947759 (rank : 17)	θ value	2.38316e-93 (rank : 17)
Query Neighborhood Hits	47	Target Neighborhood Hits	44	Shared Neighborhood Hits	35
SwissProt Accessions	Q61625	Gene names	Grid2
Domain Architecture
Description	Glutamate receptor delta-2 subunit precursor (GluR delta-2).

GRID2_HUMAN
NC score	0.947553 (rank : 18)	θ value	4.06505e-93 (rank : 18)
Query Neighborhood Hits	47	Target Neighborhood Hits	48	Shared Neighborhood Hits	35
SwissProt Accessions	O43424	Gene names	GRID2, GLURD2
Domain Architecture
Description	Glutamate receptor delta-2 subunit precursor (GluR delta-2).

GRID1_MOUSE
NC score	0.946460 (rank : 19)	θ value	7.66637e-92 (rank : 19)
Query Neighborhood Hits	47	Target Neighborhood Hits	42	Shared Neighborhood Hits	33
SwissProt Accessions	Q61627	Gene names	Grid1
Domain Architecture
Description	Glutamate receptor delta-1 subunit precursor (GluR delta-1).

GRID1_HUMAN
NC score	0.946306 (rank : 20)	θ value	1.30768e-91 (rank : 20)
Query Neighborhood Hits	47	Target Neighborhood Hits	42	Shared Neighborhood Hits	33
SwissProt Accessions	Q9ULK0, Q8IXT3	Gene names	GRID1, KIAA1220
Domain Architecture
Description	Glutamate receptor delta-1 subunit precursor (GluR delta-1).

NMDZ1_HUMAN
NC score	0.899164 (rank : 21)	θ value	4.84666e-62 (rank : 22)
Query Neighborhood Hits	47	Target Neighborhood Hits	77	Shared Neighborhood Hits	33
SwissProt Accessions	Q05586, P35437, Q12867, Q12868	Gene names	GRIN1, NMDAR1
Domain Architecture
Description	Glutamate [NMDA] receptor subunit zeta 1 precursor (N-methyl-D- aspartate receptor subunit NR1).

NMDZ1_MOUSE
NC score	0.899060 (rank : 22)	θ value	3.71096e-62 (rank : 21)
Query Neighborhood Hits	47	Target Neighborhood Hits	76	Shared Neighborhood Hits	33
SwissProt Accessions	P35438, Q8CFS4	Gene names	Grin1, Glurz1
Domain Architecture
Description	Glutamate [NMDA] receptor subunit zeta 1 precursor (N-methyl-D- aspartate receptor subunit NR1).

NMD3A_HUMAN
NC score	0.858111 (rank : 23)	θ value	1.42001e-37 (rank : 31)
Query Neighborhood Hits	47	Target Neighborhood Hits	58	Shared Neighborhood Hits	33
SwissProt Accessions	Q8TCU5, Q8TF29, Q8WXI6	Gene names	GRIN3A, KIAA1973
Domain Architecture	No domain graphic available
Description	Glutamate [NMDA] receptor subunit 3A precursor (N-methyl-D-aspartate receptor subtype NR3A) (NMDAR-L).

NMD3B_HUMAN
NC score	0.853175 (rank : 24)	θ value	2.50655e-34 (rank : 32)
Query Neighborhood Hits	47	Target Neighborhood Hits	55	Shared Neighborhood Hits	33
SwissProt Accessions	O60391, Q5EAK7, Q7RTW9	Gene names	GRIN3B
Domain Architecture	No domain graphic available
Description	Glutamate [NMDA] receptor subunit 3B precursor (N-methyl-D-aspartate receptor subtype NR3B) (NR3B) (NMDAR3B).

NMD3B_MOUSE
NC score	0.850618 (rank : 25)	θ value	2.12192e-33 (rank : 33)
Query Neighborhood Hits	47	Target Neighborhood Hits	51	Shared Neighborhood Hits	33
SwissProt Accessions	Q91ZU9, Q8VHV0	Gene names	Grin3b
Domain Architecture	No domain graphic available
Description	Glutamate [NMDA] receptor subunit 3B precursor (N-methyl-D-aspartate receptor subunit NR3B) (NR3B) (NMDAR3B) (NMDA receptor NR4) (Nr4).

NMDE4_HUMAN
NC score	0.834883 (rank : 26)	θ value	1.46607e-42 (rank : 26)
Query Neighborhood Hits	47	Target Neighborhood Hits	133	Shared Neighborhood Hits	35
SwissProt Accessions	O15399	Gene names	GRIN2D
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 4 precursor (N-methyl D- aspartate receptor subtype 2D) (NR2D) (NMDAR2D) (EB11).

NMDE4_MOUSE
NC score	0.832645 (rank : 27)	θ value	1.46607e-42 (rank : 27)
Query Neighborhood Hits	47	Target Neighborhood Hits	158	Shared Neighborhood Hits	35
SwissProt Accessions	Q03391	Gene names	Grin2d
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 4 precursor (N-methyl D- aspartate receptor subtype 2D) (NR2D) (NMDAR2D).

NMDE3_MOUSE
NC score	0.831727 (rank : 28)	θ value	2.95404e-43 (rank : 25)
Query Neighborhood Hits	47	Target Neighborhood Hits	86	Shared Neighborhood Hits	33
SwissProt Accessions	Q01098	Gene names	Grin2c
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 3 precursor (N-methyl D- aspartate receptor subtype 2C) (NR2C) (NMDAR2C).

NMDE3_HUMAN
NC score	0.829960 (rank : 29)	θ value	1.91475e-42 (rank : 28)
Query Neighborhood Hits	47	Target Neighborhood Hits	110	Shared Neighborhood Hits	33
SwissProt Accessions	Q14957	Gene names	GRIN2C
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 3 precursor (N-methyl D- aspartate receptor subtype 2C) (NR2C) (NMDAR2C).

NMDE2_MOUSE
NC score	0.829676 (rank : 30)	θ value	2.41655e-45 (rank : 23)
Query Neighborhood Hits	47	Target Neighborhood Hits	64	Shared Neighborhood Hits	35
SwissProt Accessions	Q01097, Q9DCB2	Gene names	Grin2b
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 2 precursor (N-methyl D- aspartate receptor subtype 2B) (NR2B) (NMDAR2B).

NMDE2_HUMAN
NC score	0.829526 (rank : 31)	θ value	3.15612e-45 (rank : 24)
Query Neighborhood Hits	47	Target Neighborhood Hits	65	Shared Neighborhood Hits	33
SwissProt Accessions	Q13224, Q12919, Q13220, Q13225, Q9UM56	Gene names	GRIN2B
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 2 precursor (N-methyl D- aspartate receptor subtype 2B) (NR2B) (NMDAR2B) (N-methyl-D-aspartate receptor subunit 3) (NR3) (hNR3).

NMDE1_MOUSE
NC score	0.825307 (rank : 32)	θ value	2.50074e-42 (rank : 30)
Query Neighborhood Hits	47	Target Neighborhood Hits	84	Shared Neighborhood Hits	33
SwissProt Accessions	P35436	Gene names	Grin2a
Domain Architecture	No domain graphic available
Description	Glutamate [NMDA] receptor subunit epsilon 1 precursor (N-methyl D- aspartate receptor subtype 2A) (NR2A) (NMDAR2A).

NMDE1_HUMAN
NC score	0.825165 (rank : 33)	θ value	2.50074e-42 (rank : 29)
Query Neighborhood Hits	47	Target Neighborhood Hits	81	Shared Neighborhood Hits	33
SwissProt Accessions	Q12879, O00669	Gene names	GRIN2A
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 1 precursor (N-methyl D- aspartate receptor subtype 2A) (NR2A) (NMDAR2A) (hNR2A).

GABR1_HUMAN
NC score	0.089487 (rank : 34)	θ value	0.00665767 (rank : 34)
Query Neighborhood Hits	47	Target Neighborhood Hits	142	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UBS5, O95375, O95468, O95975, O96022, Q86W60, Q9UQQ0	Gene names	GABBR1, GPRC3A
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 1 precursor (GABA-B receptor 1) (GABA-B-R1) (Gb1).

GABR1_MOUSE
NC score	0.089274 (rank : 35)	θ value	0.00665767 (rank : 35)
Query Neighborhood Hits	47	Target Neighborhood Hits	139	Shared Neighborhood Hits	15
SwissProt Accessions	Q9WV18, Q9WU48, Q9WV15, Q9WV16, Q9WV17	Gene names	Gabbr1
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 1 precursor (GABA-B receptor 1) (GABA-B-R1) (Gb1).

ERB1_HUMAN
NC score	0.052377 (rank : 36)	θ value	θ > 10 (rank : 48)
Query Neighborhood Hits	47	Target Neighborhood Hits	23	Shared Neighborhood Hits	8
SwissProt Accessions	P60509	Gene names
Domain Architecture	No domain graphic available
Description	HERV-R(b)_3p24.3 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (HERV-R(b) Env protein) [Includes: Surface protein domain (SU); Transmembrane protein domain (TM)].

PEPD_MOUSE
NC score	0.016972 (rank : 37)	θ value	2.36792 (rank : 38)
Query Neighborhood Hits	47	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q11136, P97735, Q3TH86, Q9CWK4	Gene names	Pepd, Pep4
Domain Architecture
Description	Xaa-Pro dipeptidase (EC 3.4.13.9) (X-Pro dipeptidase) (Proline dipeptidase) (Prolidase) (Imidodipeptidase) (Peptidase 4).

HELC1_HUMAN
NC score	0.016326 (rank : 38)	θ value	3.0926 (rank : 39)
Query Neighborhood Hits	47	Target Neighborhood Hits	71	Shared Neighborhood Hits	5
SwissProt Accessions	Q8N3C0, O43738, Q9H1I9, Q9NTR0	Gene names	ASCC3, HELIC1
Domain Architecture	No domain graphic available
Description	Activating signal cointegrator 1 complex subunit 3 (EC 3.6.1.-) (ASC-1 complex subunit p200) (Trip4 complex subunit p200) (Helicase, ATP binding 1).

IF4A1_HUMAN
NC score	0.016005 (rank : 39)	θ value	3.0926 (rank : 40)
Query Neighborhood Hits	47	Target Neighborhood Hits	106	Shared Neighborhood Hits	12
SwissProt Accessions	P60842, P04765, Q5U018, Q61516	Gene names	EIF4A1, DDX2A, EIF4A
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

IF4A1_MOUSE
NC score	0.016005 (rank : 40)	θ value	3.0926 (rank : 41)
Query Neighborhood Hits	47	Target Neighborhood Hits	106	Shared Neighborhood Hits	12
SwissProt Accessions	P60843, P04765, Q61516	Gene names	Eif4a1, Ddx2a, Eif4a
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

IF4A2_HUMAN
NC score	0.014268 (rank : 41)	θ value	4.03905 (rank : 42)
Query Neighborhood Hits	47	Target Neighborhood Hits	102	Shared Neighborhood Hits	12
SwissProt Accessions	Q14240, Q96B90, Q96EA8	Gene names	EIF4A2, DDX2B
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

IF4A2_MOUSE
NC score	0.014268 (rank : 42)	θ value	4.03905 (rank : 43)
Query Neighborhood Hits	47	Target Neighborhood Hits	102	Shared Neighborhood Hits	12
SwissProt Accessions	P10630, Q61513, Q61514	Gene names	Eif4a2, Ddx2b
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

DDX48_MOUSE
NC score	0.012610 (rank : 43)	θ value	1.06291 (rank : 37)
Query Neighborhood Hits	47	Target Neighborhood Hits	102	Shared Neighborhood Hits	10
SwissProt Accessions	Q91VC3	Gene names	Ddx48
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48).

DDX48_HUMAN
NC score	0.012589 (rank : 44)	θ value	1.06291 (rank : 36)
Query Neighborhood Hits	47	Target Neighborhood Hits	102	Shared Neighborhood Hits	10
SwissProt Accessions	P38919, Q15033, Q96A18	Gene names	DDX48, EIF4A3, KIAA0111
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX48 (EC 3.6.1.-) (DEAD box protein 48) (Eukaryotic initiation factor 4A-like NUK-34) (Nuclear matrix protein 265) (hNMP 265) (Eukaryotic translation initiation factor 4A isoform 3).

SMYD2_HUMAN
NC score	0.007897 (rank : 45)	θ value	5.27518 (rank : 44)
Query Neighborhood Hits	47	Target Neighborhood Hits	37	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NRG4, Q4V765, Q5VSH9	Gene names	SMYD2
Domain Architecture
Description	SET and MYND domain-containing protein 2 (HSKM-B).

TR150_HUMAN
NC score	0.006891 (rank : 46)	θ value	8.99809 (rank : 46)
Query Neighborhood Hits	47	Target Neighborhood Hits	313	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y2W1, Q5VTK6	Gene names	THRAP3, TRAP150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

TR150_MOUSE
NC score	0.005118 (rank : 47)	θ value	8.99809 (rank : 47)
Query Neighborhood Hits	47	Target Neighborhood Hits	468	Shared Neighborhood Hits	4
SwissProt Accessions	Q569Z6	Gene names	Thrap3, Trap150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

SEPT5_HUMAN
NC score	0.002327 (rank : 48)	θ value	8.99809 (rank : 45)
Query Neighborhood Hits	47	Target Neighborhood Hits	44	Shared Neighborhood Hits	3
SwissProt Accessions	Q99719, O15251	Gene names	SEPT5, PNUTL1
Domain Architecture
Description	Septin-5 (Peanut-like protein 1) (Cell division control-related protein 1) (CDCrel-1).