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Network neighborhood for query Sequence : GRIA4_HUMAN

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GRIA4_HUMAN
SwissProt Accessions	P48058	Gene names	GRIA4, GLUR4
Domain Architecture
Description	Glutamate receptor 4 precursor (GluR-4) (GluR4) (GluR-D) (Glutamate receptor ionotropic, AMPA 4) (AMPA-selective glutamate receptor 4).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

GRIA1_HUMAN
θ value	0 (rank : 1)	NC score	0.997890 (rank : 7)
Query Neighborhood Hits	45	Target Neighborhood Hits	45	Shared Neighborhood Hits	37
SwissProt Accessions	P42261	Gene names	GRIA1, GLUH1, GLUR1
Domain Architecture
Description	Glutamate receptor 1 precursor (GluR-1) (GluR-A) (GluR-K1) (Glutamate receptor ionotropic, AMPA 1) (AMPA-selective glutamate receptor 1).

GRIA1_MOUSE
θ value	0 (rank : 2)	NC score	0.997878 (rank : 8)
Query Neighborhood Hits	45	Target Neighborhood Hits	46	Shared Neighborhood Hits	37
SwissProt Accessions	P23818	Gene names	Gria1, Glur1
Domain Architecture
Description	Glutamate receptor 1 precursor (GluR-1) (GluR-A) (GluR-K1) (Glutamate receptor ionotropic, AMPA 1) (AMPA-selective glutamate receptor 1).

GRIA2_HUMAN
θ value	0 (rank : 3)	NC score	0.998098 (rank : 5)
Query Neighborhood Hits	45	Target Neighborhood Hits	47	Shared Neighborhood Hits	37
SwissProt Accessions	P42262, Q96FP6	Gene names	GRIA2, GLUR2
Domain Architecture
Description	Glutamate receptor 2 precursor (GluR-2) (GluR-B) (GluR-K2) (Glutamate receptor ionotropic, AMPA 2) (AMPA-selective glutamate receptor 2).

GRIA2_MOUSE
θ value	0 (rank : 4)	NC score	0.998093 (rank : 6)
Query Neighborhood Hits	45	Target Neighborhood Hits	47	Shared Neighborhood Hits	37
SwissProt Accessions	P23819, Q61604, Q61605, Q8BG69, Q8BXU3, Q9D6D3	Gene names	Gria2, Glur2
Domain Architecture
Description	Glutamate receptor 2 precursor (GluR-2) (GluR-B) (GluR-K2) (Glutamate receptor ionotropic, AMPA 2) (AMPA-selective glutamate receptor 2).

GRIA3_HUMAN
θ value	0 (rank : 5)	NC score	0.998711 (rank : 3)
Query Neighborhood Hits	45	Target Neighborhood Hits	40	Shared Neighborhood Hits	34
SwissProt Accessions	P42263, Q4VXD5, Q4VXD6, Q9HDA0, Q9HDA1, Q9HDA2	Gene names	GRIA3, GLUR3, GLURC
Domain Architecture
Description	Glutamate receptor 3 precursor (GluR-3) (GluR-C) (GluR-K3) (Glutamate receptor ionotropic, AMPA 3) (AMPA-selective glutamate receptor 3).

GRIA3_MOUSE
θ value	0 (rank : 6)	NC score	0.998678 (rank : 4)
Query Neighborhood Hits	45	Target Neighborhood Hits	39	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Z2W9, Q5DTJ0	Gene names	Gria3, Glur3, Kiaa4184
Domain Architecture	No domain graphic available
Description	Glutamate receptor 3 precursor (GluR-3) (GluR-C) (GluR-K3) (Glutamate receptor ionotropic, AMPA 3) (AMPA-selective glutamate receptor 3).

GRIA4_HUMAN
θ value	0 (rank : 7)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	45	Target Neighborhood Hits	45	Shared Neighborhood Hits	45
SwissProt Accessions	P48058	Gene names	GRIA4, GLUR4
Domain Architecture
Description	Glutamate receptor 4 precursor (GluR-4) (GluR4) (GluR-D) (Glutamate receptor ionotropic, AMPA 4) (AMPA-selective glutamate receptor 4).

GRIA4_MOUSE
θ value	0 (rank : 8)	NC score	0.999935 (rank : 2)
Query Neighborhood Hits	45	Target Neighborhood Hits	44	Shared Neighborhood Hits	44
SwissProt Accessions	Q9Z2W8	Gene names	Gria4, Glur4
Domain Architecture
Description	Glutamate receptor 4 precursor (GluR-4) (GluR4) (GluR-D) (Glutamate receptor ionotropic, AMPA 4) (AMPA-selective glutamate receptor 4).

GRIK2_HUMAN
θ value	1.01238e-168 (rank : 9)	NC score	0.978565 (rank : 10)
Query Neighborhood Hits	45	Target Neighborhood Hits	50	Shared Neighborhood Hits	34
SwissProt Accessions	Q13002	Gene names	GRIK2, GLUR6
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 2 precursor (Glutamate receptor 6) (GluR-6) (GluR6) (Excitatory amino acid receptor 4) (EAA4).

GRIK1_HUMAN
θ value	3.85598e-160 (rank : 10)	NC score	0.977385 (rank : 11)
Query Neighborhood Hits	45	Target Neighborhood Hits	48	Shared Neighborhood Hits	34
SwissProt Accessions	P39086, Q13001, Q86SU9	Gene names	GRIK1, GLUR5
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 1 precursor (Glutamate receptor 5) (GluR-5) (GluR5) (Excitatory amino acid receptor 3) (EAA3).

GRIK3_HUMAN
θ value	6.57732e-160 (rank : 11)	NC score	0.979405 (rank : 9)
Query Neighborhood Hits	45	Target Neighborhood Hits	41	Shared Neighborhood Hits	34
SwissProt Accessions	Q13003, Q13004, Q16136	Gene names	GRIK3, GLUR7
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 3 precursor (Glutamate receptor 7) (GluR-7) (GluR7) (Excitatory amino acid receptor 5) (EAA5).

GRIK5_MOUSE
θ value	4.73554e-142 (rank : 12)	NC score	0.973824 (rank : 13)
Query Neighborhood Hits	45	Target Neighborhood Hits	47	Shared Neighborhood Hits	33
SwissProt Accessions	Q61626	Gene names	Grik5
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 5 precursor (Glutamate receptor KA-2) (KA2) (Glutamate receptor gamma-2) (GluR gamma-2).

GRIK5_HUMAN
θ value	5.78879e-140 (rank : 13)	NC score	0.973667 (rank : 14)
Query Neighborhood Hits	45	Target Neighborhood Hits	44	Shared Neighborhood Hits	33
SwissProt Accessions	Q16478	Gene names	GRIK5, GRIK2
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 5 precursor (Glutamate receptor KA-2) (KA2) (Excitatory amino acid receptor 2) (EAA2).

GRIK4_HUMAN
θ value	2.87295e-139 (rank : 14)	NC score	0.973516 (rank : 15)
Query Neighborhood Hits	45	Target Neighborhood Hits	42	Shared Neighborhood Hits	34
SwissProt Accessions	Q16099	Gene names	GRIK4, GRIK
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 4 precursor (Glutamate receptor KA-1) (KA1) (Excitatory amino acid receptor 1) (EAA1).

GRIK4_MOUSE
θ value	8.35901e-139 (rank : 15)	NC score	0.973229 (rank : 16)
Query Neighborhood Hits	45	Target Neighborhood Hits	41	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BMF5	Gene names	Grik4
Domain Architecture	No domain graphic available
Description	Glutamate receptor, ionotropic kainate 4 precursor.

GRIK1_MOUSE
θ value	1.24909e-134 (rank : 16)	NC score	0.975620 (rank : 12)
Query Neighborhood Hits	45	Target Neighborhood Hits	46	Shared Neighborhood Hits	34
SwissProt Accessions	Q60934	Gene names	Grik1, Glur5
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 1 precursor (Glutamate receptor 5) (GluR-5) (GluR5).

GRID2_MOUSE
θ value	9.37149e-90 (rank : 17)	NC score	0.945736 (rank : 17)
Query Neighborhood Hits	45	Target Neighborhood Hits	44	Shared Neighborhood Hits	33
SwissProt Accessions	Q61625	Gene names	Grid2
Domain Architecture
Description	Glutamate receptor delta-2 subunit precursor (GluR delta-2).

GRID2_HUMAN
θ value	3.93732e-88 (rank : 18)	NC score	0.945376 (rank : 18)
Query Neighborhood Hits	45	Target Neighborhood Hits	48	Shared Neighborhood Hits	33
SwissProt Accessions	O43424	Gene names	GRID2, GLURD2
Domain Architecture
Description	Glutamate receptor delta-2 subunit precursor (GluR delta-2).

GRID1_MOUSE
θ value	3.68522e-86 (rank : 19)	NC score	0.944534 (rank : 19)
Query Neighborhood Hits	45	Target Neighborhood Hits	42	Shared Neighborhood Hits	33
SwissProt Accessions	Q61627	Gene names	Grid1
Domain Architecture
Description	Glutamate receptor delta-1 subunit precursor (GluR delta-1).

GRID1_HUMAN
θ value	6.95003e-85 (rank : 20)	NC score	0.944307 (rank : 20)
Query Neighborhood Hits	45	Target Neighborhood Hits	42	Shared Neighborhood Hits	33
SwissProt Accessions	Q9ULK0, Q8IXT3	Gene names	GRID1, KIAA1220
Domain Architecture
Description	Glutamate receptor delta-1 subunit precursor (GluR delta-1).

NMDZ1_MOUSE
θ value	8.00737e-57 (rank : 21)	NC score	0.898044 (rank : 22)
Query Neighborhood Hits	45	Target Neighborhood Hits	76	Shared Neighborhood Hits	35
SwissProt Accessions	P35438, Q8CFS4	Gene names	Grin1, Glurz1
Domain Architecture
Description	Glutamate [NMDA] receptor subunit zeta 1 precursor (N-methyl-D- aspartate receptor subunit NR1).

NMDZ1_HUMAN
θ value	2.32979e-56 (rank : 22)	NC score	0.898120 (rank : 21)
Query Neighborhood Hits	45	Target Neighborhood Hits	77	Shared Neighborhood Hits	35
SwissProt Accessions	Q05586, P35437, Q12867, Q12868	Gene names	GRIN1, NMDAR1
Domain Architecture
Description	Glutamate [NMDA] receptor subunit zeta 1 precursor (N-methyl-D- aspartate receptor subunit NR1).

NMDE2_HUMAN
θ value	1.15895e-47 (rank : 23)	NC score	0.831684 (rank : 30)
Query Neighborhood Hits	45	Target Neighborhood Hits	65	Shared Neighborhood Hits	33
SwissProt Accessions	Q13224, Q12919, Q13220, Q13225, Q9UM56	Gene names	GRIN2B
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 2 precursor (N-methyl D- aspartate receptor subtype 2B) (NR2B) (NMDAR2B) (N-methyl-D-aspartate receptor subunit 3) (NR3) (hNR3).

NMDE2_MOUSE
θ value	1.97686e-47 (rank : 24)	NC score	0.831645 (rank : 31)
Query Neighborhood Hits	45	Target Neighborhood Hits	64	Shared Neighborhood Hits	33
SwissProt Accessions	Q01097, Q9DCB2	Gene names	Grin2b
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 2 precursor (N-methyl D- aspartate receptor subtype 2B) (NR2B) (NMDAR2B).

NMDE3_MOUSE
θ value	1.28137e-46 (rank : 25)	NC score	0.834166 (rank : 27)
Query Neighborhood Hits	45	Target Neighborhood Hits	86	Shared Neighborhood Hits	33
SwissProt Accessions	Q01098	Gene names	Grin2c
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 3 precursor (N-methyl D- aspartate receptor subtype 2C) (NR2C) (NMDAR2C).

NMDE3_HUMAN
θ value	8.30557e-46 (rank : 26)	NC score	0.832390 (rank : 29)
Query Neighborhood Hits	45	Target Neighborhood Hits	110	Shared Neighborhood Hits	33
SwissProt Accessions	Q14957	Gene names	GRIN2C
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 3 precursor (N-methyl D- aspartate receptor subtype 2C) (NR2C) (NMDAR2C).

NMDE4_HUMAN
θ value	3.85808e-43 (rank : 27)	NC score	0.835953 (rank : 26)
Query Neighborhood Hits	45	Target Neighborhood Hits	133	Shared Neighborhood Hits	33
SwissProt Accessions	O15399	Gene names	GRIN2D
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 4 precursor (N-methyl D- aspartate receptor subtype 2D) (NR2D) (NMDAR2D) (EB11).

NMDE4_MOUSE
θ value	3.85808e-43 (rank : 28)	NC score	0.833793 (rank : 28)
Query Neighborhood Hits	45	Target Neighborhood Hits	158	Shared Neighborhood Hits	33
SwissProt Accessions	Q03391	Gene names	Grin2d
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 4 precursor (N-methyl D- aspartate receptor subtype 2D) (NR2D) (NMDAR2D).

NMDE1_HUMAN
θ value	6.58091e-43 (rank : 29)	NC score	0.827029 (rank : 33)
Query Neighborhood Hits	45	Target Neighborhood Hits	81	Shared Neighborhood Hits	33
SwissProt Accessions	Q12879, O00669	Gene names	GRIN2A
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 1 precursor (N-methyl D- aspartate receptor subtype 2A) (NR2A) (NMDAR2A) (hNR2A).

NMDE1_MOUSE
θ value	8.59492e-43 (rank : 30)	NC score	0.827156 (rank : 32)
Query Neighborhood Hits	45	Target Neighborhood Hits	84	Shared Neighborhood Hits	33
SwissProt Accessions	P35436	Gene names	Grin2a
Domain Architecture	No domain graphic available
Description	Glutamate [NMDA] receptor subunit epsilon 1 precursor (N-methyl D- aspartate receptor subtype 2A) (NR2A) (NMDAR2A).

NMD3A_HUMAN
θ value	1.32909e-35 (rank : 31)	NC score	0.857224 (rank : 23)
Query Neighborhood Hits	45	Target Neighborhood Hits	58	Shared Neighborhood Hits	33
SwissProt Accessions	Q8TCU5, Q8TF29, Q8WXI6	Gene names	GRIN3A, KIAA1973
Domain Architecture	No domain graphic available
Description	Glutamate [NMDA] receptor subunit 3A precursor (N-methyl-D-aspartate receptor subtype NR3A) (NMDAR-L).

NMD3B_HUMAN
θ value	2.34606e-32 (rank : 32)	NC score	0.852092 (rank : 24)
Query Neighborhood Hits	45	Target Neighborhood Hits	55	Shared Neighborhood Hits	33
SwissProt Accessions	O60391, Q5EAK7, Q7RTW9	Gene names	GRIN3B
Domain Architecture	No domain graphic available
Description	Glutamate [NMDA] receptor subunit 3B precursor (N-methyl-D-aspartate receptor subtype NR3B) (NR3B) (NMDAR3B).

NMD3B_MOUSE
θ value	5.22648e-32 (rank : 33)	NC score	0.849608 (rank : 25)
Query Neighborhood Hits	45	Target Neighborhood Hits	51	Shared Neighborhood Hits	33
SwissProt Accessions	Q91ZU9, Q8VHV0	Gene names	Grin3b
Domain Architecture	No domain graphic available
Description	Glutamate [NMDA] receptor subunit 3B precursor (N-methyl-D-aspartate receptor subunit NR3B) (NR3B) (NMDAR3B) (NMDA receptor NR4) (Nr4).

TBLX_MOUSE
θ value	0.62314 (rank : 34)	NC score	0.012817 (rank : 38)
Query Neighborhood Hits	45	Target Neighborhood Hits	335	Shared Neighborhood Hits	7
SwissProt Accessions	Q9QXE7, Q8BMM0, Q8BYQ4, Q8C0A1	Gene names	Tbl1x, Tbl1
Domain Architecture
Description	F-box-like/WD repeat protein TBL1X (Transducin beta-like 1X protein).

TBL1Y_HUMAN
θ value	1.06291 (rank : 35)	NC score	0.012362 (rank : 41)
Query Neighborhood Hits	45	Target Neighborhood Hits	331	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BQ87	Gene names	TBL1Y, TBL1
Domain Architecture
Description	F-box-like/WD repeat protein TBL1Y (Transducin beta-like 1Y protein) (Transducin-beta-like 1, Y-linked).

GUC2G_MOUSE
θ value	1.38821 (rank : 36)	NC score	0.011534 (rank : 45)
Query Neighborhood Hits	45	Target Neighborhood Hits	644	Shared Neighborhood Hits	9
SwissProt Accessions	Q6TL19, Q8BWU7	Gene names	Gucy2g
Domain Architecture	No domain graphic available
Description	Guanylate cyclase 2G precursor (EC 4.6.1.2) (Guanylyl cyclase receptor G) (mGC-G).

TBL1R_HUMAN
θ value	1.38821 (rank : 37)	NC score	0.011707 (rank : 43)
Query Neighborhood Hits	45	Target Neighborhood Hits	327	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BZK7, Q9H2I1, Q9H9A1	Gene names	TBL1XR1, IRA1, TBLR1
Domain Architecture
Description	F-box-like/WD repeat protein TBL1XR1 (Transducin beta-like 1X-related protein 1) (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1) (TBL1-related protein 1).

TBL1R_MOUSE
θ value	1.38821 (rank : 38)	NC score	0.011698 (rank : 44)
Query Neighborhood Hits	45	Target Neighborhood Hits	329	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BHJ5, Q3UWL6, Q8CBG4, Q8VEG3, Q9EQD4	Gene names	Tbl1xr1, Ira1, Tblr1
Domain Architecture
Description	F-box-like/WD repeat protein TBL1XR1 (Transducin beta-like 1X-related protein 1) (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1) (TBL1-related protein 1).

TBL1X_HUMAN
θ value	1.38821 (rank : 39)	NC score	0.011971 (rank : 42)
Query Neighborhood Hits	45	Target Neighborhood Hits	329	Shared Neighborhood Hits	7
SwissProt Accessions	O60907, Q86UY2	Gene names	TBL1X, TBL1
Domain Architecture
Description	F-box-like/WD repeat protein TBL1X (Transducin beta-like 1X protein) (Transducin-beta-like 1, X-linked) (SMAP55).

IF4A1_HUMAN
θ value	3.0926 (rank : 40)	NC score	0.012398 (rank : 39)
Query Neighborhood Hits	45	Target Neighborhood Hits	106	Shared Neighborhood Hits	10
SwissProt Accessions	P60842, P04765, Q5U018, Q61516	Gene names	EIF4A1, DDX2A, EIF4A
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

IF4A1_MOUSE
θ value	3.0926 (rank : 41)	NC score	0.012398 (rank : 40)
Query Neighborhood Hits	45	Target Neighborhood Hits	106	Shared Neighborhood Hits	10
SwissProt Accessions	P60843, P04765, Q61516	Gene names	Eif4a1, Ddx2a, Eif4a
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

TS1R2_MOUSE
θ value	3.0926 (rank : 42)	NC score	0.035096 (rank : 37)
Query Neighborhood Hits	45	Target Neighborhood Hits	69	Shared Neighborhood Hits	9
SwissProt Accessions	Q925I4, Q923J8	Gene names	Tas1r2, Gpr71, T1r2, Tr2
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 2 precursor (G-protein coupled receptor 71) (Sweet taste receptor T1R2).

IF4A2_HUMAN
θ value	5.27518 (rank : 43)	NC score	0.010600 (rank : 46)
Query Neighborhood Hits	45	Target Neighborhood Hits	102	Shared Neighborhood Hits	10
SwissProt Accessions	Q14240, Q96B90, Q96EA8	Gene names	EIF4A2, DDX2B
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

IF4A2_MOUSE
θ value	5.27518 (rank : 44)	NC score	0.010600 (rank : 47)
Query Neighborhood Hits	45	Target Neighborhood Hits	102	Shared Neighborhood Hits	10
SwissProt Accessions	P10630, Q61513, Q61514	Gene names	Eif4a2, Ddx2b
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

PMVK_MOUSE
θ value	8.99809 (rank : 45)	NC score	0.006289 (rank : 48)
Query Neighborhood Hits	45	Target Neighborhood Hits	4	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D1G2, Q8R021, Q9D6K3	Gene names	Pmvk
Domain Architecture
Description	Phosphomevalonate kinase (EC 2.7.4.2) (PMKase).

ERB1_HUMAN
θ value	θ > 10 (rank : 46)	NC score	0.053477 (rank : 36)
Query Neighborhood Hits	45	Target Neighborhood Hits	23	Shared Neighborhood Hits	8
SwissProt Accessions	P60509	Gene names
Domain Architecture	No domain graphic available
Description	HERV-R(b)_3p24.3 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (HERV-R(b) Env protein) [Includes: Surface protein domain (SU); Transmembrane protein domain (TM)].

GABR1_HUMAN
θ value	θ > 10 (rank : 47)	NC score	0.065160 (rank : 34)
Query Neighborhood Hits	45	Target Neighborhood Hits	142	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UBS5, O95375, O95468, O95975, O96022, Q86W60, Q9UQQ0	Gene names	GABBR1, GPRC3A
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 1 precursor (GABA-B receptor 1) (GABA-B-R1) (Gb1).

GABR1_MOUSE
θ value	θ > 10 (rank : 48)	NC score	0.064980 (rank : 35)
Query Neighborhood Hits	45	Target Neighborhood Hits	139	Shared Neighborhood Hits	15
SwissProt Accessions	Q9WV18, Q9WU48, Q9WV15, Q9WV16, Q9WV17	Gene names	Gabbr1
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 1 precursor (GABA-B receptor 1) (GABA-B-R1) (Gb1).

Hits sorted by NC score

GRIA4_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 7)
Query Neighborhood Hits	45	Target Neighborhood Hits	45	Shared Neighborhood Hits	45
SwissProt Accessions	P48058	Gene names	GRIA4, GLUR4
Domain Architecture
Description	Glutamate receptor 4 precursor (GluR-4) (GluR4) (GluR-D) (Glutamate receptor ionotropic, AMPA 4) (AMPA-selective glutamate receptor 4).

GRIA4_MOUSE
NC score	0.999935 (rank : 2)	θ value	0 (rank : 8)
Query Neighborhood Hits	45	Target Neighborhood Hits	44	Shared Neighborhood Hits	44
SwissProt Accessions	Q9Z2W8	Gene names	Gria4, Glur4
Domain Architecture
Description	Glutamate receptor 4 precursor (GluR-4) (GluR4) (GluR-D) (Glutamate receptor ionotropic, AMPA 4) (AMPA-selective glutamate receptor 4).

GRIA3_HUMAN
NC score	0.998711 (rank : 3)	θ value	0 (rank : 5)
Query Neighborhood Hits	45	Target Neighborhood Hits	40	Shared Neighborhood Hits	34
SwissProt Accessions	P42263, Q4VXD5, Q4VXD6, Q9HDA0, Q9HDA1, Q9HDA2	Gene names	GRIA3, GLUR3, GLURC
Domain Architecture
Description	Glutamate receptor 3 precursor (GluR-3) (GluR-C) (GluR-K3) (Glutamate receptor ionotropic, AMPA 3) (AMPA-selective glutamate receptor 3).

GRIA3_MOUSE
NC score	0.998678 (rank : 4)	θ value	0 (rank : 6)
Query Neighborhood Hits	45	Target Neighborhood Hits	39	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Z2W9, Q5DTJ0	Gene names	Gria3, Glur3, Kiaa4184
Domain Architecture	No domain graphic available
Description	Glutamate receptor 3 precursor (GluR-3) (GluR-C) (GluR-K3) (Glutamate receptor ionotropic, AMPA 3) (AMPA-selective glutamate receptor 3).

GRIA2_HUMAN
NC score	0.998098 (rank : 5)	θ value	0 (rank : 3)
Query Neighborhood Hits	45	Target Neighborhood Hits	47	Shared Neighborhood Hits	37
SwissProt Accessions	P42262, Q96FP6	Gene names	GRIA2, GLUR2
Domain Architecture
Description	Glutamate receptor 2 precursor (GluR-2) (GluR-B) (GluR-K2) (Glutamate receptor ionotropic, AMPA 2) (AMPA-selective glutamate receptor 2).

GRIA2_MOUSE
NC score	0.998093 (rank : 6)	θ value	0 (rank : 4)
Query Neighborhood Hits	45	Target Neighborhood Hits	47	Shared Neighborhood Hits	37
SwissProt Accessions	P23819, Q61604, Q61605, Q8BG69, Q8BXU3, Q9D6D3	Gene names	Gria2, Glur2
Domain Architecture
Description	Glutamate receptor 2 precursor (GluR-2) (GluR-B) (GluR-K2) (Glutamate receptor ionotropic, AMPA 2) (AMPA-selective glutamate receptor 2).

GRIA1_HUMAN
NC score	0.997890 (rank : 7)	θ value	0 (rank : 1)
Query Neighborhood Hits	45	Target Neighborhood Hits	45	Shared Neighborhood Hits	37
SwissProt Accessions	P42261	Gene names	GRIA1, GLUH1, GLUR1
Domain Architecture
Description	Glutamate receptor 1 precursor (GluR-1) (GluR-A) (GluR-K1) (Glutamate receptor ionotropic, AMPA 1) (AMPA-selective glutamate receptor 1).

GRIA1_MOUSE
NC score	0.997878 (rank : 8)	θ value	0 (rank : 2)
Query Neighborhood Hits	45	Target Neighborhood Hits	46	Shared Neighborhood Hits	37
SwissProt Accessions	P23818	Gene names	Gria1, Glur1
Domain Architecture
Description	Glutamate receptor 1 precursor (GluR-1) (GluR-A) (GluR-K1) (Glutamate receptor ionotropic, AMPA 1) (AMPA-selective glutamate receptor 1).

GRIK3_HUMAN
NC score	0.979405 (rank : 9)	θ value	6.57732e-160 (rank : 11)
Query Neighborhood Hits	45	Target Neighborhood Hits	41	Shared Neighborhood Hits	34
SwissProt Accessions	Q13003, Q13004, Q16136	Gene names	GRIK3, GLUR7
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 3 precursor (Glutamate receptor 7) (GluR-7) (GluR7) (Excitatory amino acid receptor 5) (EAA5).

GRIK2_HUMAN
NC score	0.978565 (rank : 10)	θ value	1.01238e-168 (rank : 9)
Query Neighborhood Hits	45	Target Neighborhood Hits	50	Shared Neighborhood Hits	34
SwissProt Accessions	Q13002	Gene names	GRIK2, GLUR6
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 2 precursor (Glutamate receptor 6) (GluR-6) (GluR6) (Excitatory amino acid receptor 4) (EAA4).

GRIK1_HUMAN
NC score	0.977385 (rank : 11)	θ value	3.85598e-160 (rank : 10)
Query Neighborhood Hits	45	Target Neighborhood Hits	48	Shared Neighborhood Hits	34
SwissProt Accessions	P39086, Q13001, Q86SU9	Gene names	GRIK1, GLUR5
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 1 precursor (Glutamate receptor 5) (GluR-5) (GluR5) (Excitatory amino acid receptor 3) (EAA3).

GRIK1_MOUSE
NC score	0.975620 (rank : 12)	θ value	1.24909e-134 (rank : 16)
Query Neighborhood Hits	45	Target Neighborhood Hits	46	Shared Neighborhood Hits	34
SwissProt Accessions	Q60934	Gene names	Grik1, Glur5
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 1 precursor (Glutamate receptor 5) (GluR-5) (GluR5).

GRIK5_MOUSE
NC score	0.973824 (rank : 13)	θ value	4.73554e-142 (rank : 12)
Query Neighborhood Hits	45	Target Neighborhood Hits	47	Shared Neighborhood Hits	33
SwissProt Accessions	Q61626	Gene names	Grik5
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 5 precursor (Glutamate receptor KA-2) (KA2) (Glutamate receptor gamma-2) (GluR gamma-2).

GRIK5_HUMAN
NC score	0.973667 (rank : 14)	θ value	5.78879e-140 (rank : 13)
Query Neighborhood Hits	45	Target Neighborhood Hits	44	Shared Neighborhood Hits	33
SwissProt Accessions	Q16478	Gene names	GRIK5, GRIK2
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 5 precursor (Glutamate receptor KA-2) (KA2) (Excitatory amino acid receptor 2) (EAA2).

GRIK4_HUMAN
NC score	0.973516 (rank : 15)	θ value	2.87295e-139 (rank : 14)
Query Neighborhood Hits	45	Target Neighborhood Hits	42	Shared Neighborhood Hits	34
SwissProt Accessions	Q16099	Gene names	GRIK4, GRIK
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 4 precursor (Glutamate receptor KA-1) (KA1) (Excitatory amino acid receptor 1) (EAA1).

GRIK4_MOUSE
NC score	0.973229 (rank : 16)	θ value	8.35901e-139 (rank : 15)
Query Neighborhood Hits	45	Target Neighborhood Hits	41	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BMF5	Gene names	Grik4
Domain Architecture	No domain graphic available
Description	Glutamate receptor, ionotropic kainate 4 precursor.

GRID2_MOUSE
NC score	0.945736 (rank : 17)	θ value	9.37149e-90 (rank : 17)
Query Neighborhood Hits	45	Target Neighborhood Hits	44	Shared Neighborhood Hits	33
SwissProt Accessions	Q61625	Gene names	Grid2
Domain Architecture
Description	Glutamate receptor delta-2 subunit precursor (GluR delta-2).

GRID2_HUMAN
NC score	0.945376 (rank : 18)	θ value	3.93732e-88 (rank : 18)
Query Neighborhood Hits	45	Target Neighborhood Hits	48	Shared Neighborhood Hits	33
SwissProt Accessions	O43424	Gene names	GRID2, GLURD2
Domain Architecture
Description	Glutamate receptor delta-2 subunit precursor (GluR delta-2).

GRID1_MOUSE
NC score	0.944534 (rank : 19)	θ value	3.68522e-86 (rank : 19)
Query Neighborhood Hits	45	Target Neighborhood Hits	42	Shared Neighborhood Hits	33
SwissProt Accessions	Q61627	Gene names	Grid1
Domain Architecture
Description	Glutamate receptor delta-1 subunit precursor (GluR delta-1).

GRID1_HUMAN
NC score	0.944307 (rank : 20)	θ value	6.95003e-85 (rank : 20)
Query Neighborhood Hits	45	Target Neighborhood Hits	42	Shared Neighborhood Hits	33
SwissProt Accessions	Q9ULK0, Q8IXT3	Gene names	GRID1, KIAA1220
Domain Architecture
Description	Glutamate receptor delta-1 subunit precursor (GluR delta-1).

NMDZ1_HUMAN
NC score	0.898120 (rank : 21)	θ value	2.32979e-56 (rank : 22)
Query Neighborhood Hits	45	Target Neighborhood Hits	77	Shared Neighborhood Hits	35
SwissProt Accessions	Q05586, P35437, Q12867, Q12868	Gene names	GRIN1, NMDAR1
Domain Architecture
Description	Glutamate [NMDA] receptor subunit zeta 1 precursor (N-methyl-D- aspartate receptor subunit NR1).

NMDZ1_MOUSE
NC score	0.898044 (rank : 22)	θ value	8.00737e-57 (rank : 21)
Query Neighborhood Hits	45	Target Neighborhood Hits	76	Shared Neighborhood Hits	35
SwissProt Accessions	P35438, Q8CFS4	Gene names	Grin1, Glurz1
Domain Architecture
Description	Glutamate [NMDA] receptor subunit zeta 1 precursor (N-methyl-D- aspartate receptor subunit NR1).

NMD3A_HUMAN
NC score	0.857224 (rank : 23)	θ value	1.32909e-35 (rank : 31)
Query Neighborhood Hits	45	Target Neighborhood Hits	58	Shared Neighborhood Hits	33
SwissProt Accessions	Q8TCU5, Q8TF29, Q8WXI6	Gene names	GRIN3A, KIAA1973
Domain Architecture	No domain graphic available
Description	Glutamate [NMDA] receptor subunit 3A precursor (N-methyl-D-aspartate receptor subtype NR3A) (NMDAR-L).

NMD3B_HUMAN
NC score	0.852092 (rank : 24)	θ value	2.34606e-32 (rank : 32)
Query Neighborhood Hits	45	Target Neighborhood Hits	55	Shared Neighborhood Hits	33
SwissProt Accessions	O60391, Q5EAK7, Q7RTW9	Gene names	GRIN3B
Domain Architecture	No domain graphic available
Description	Glutamate [NMDA] receptor subunit 3B precursor (N-methyl-D-aspartate receptor subtype NR3B) (NR3B) (NMDAR3B).

NMD3B_MOUSE
NC score	0.849608 (rank : 25)	θ value	5.22648e-32 (rank : 33)
Query Neighborhood Hits	45	Target Neighborhood Hits	51	Shared Neighborhood Hits	33
SwissProt Accessions	Q91ZU9, Q8VHV0	Gene names	Grin3b
Domain Architecture	No domain graphic available
Description	Glutamate [NMDA] receptor subunit 3B precursor (N-methyl-D-aspartate receptor subunit NR3B) (NR3B) (NMDAR3B) (NMDA receptor NR4) (Nr4).

NMDE4_HUMAN
NC score	0.835953 (rank : 26)	θ value	3.85808e-43 (rank : 27)
Query Neighborhood Hits	45	Target Neighborhood Hits	133	Shared Neighborhood Hits	33
SwissProt Accessions	O15399	Gene names	GRIN2D
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 4 precursor (N-methyl D- aspartate receptor subtype 2D) (NR2D) (NMDAR2D) (EB11).

NMDE3_MOUSE
NC score	0.834166 (rank : 27)	θ value	1.28137e-46 (rank : 25)
Query Neighborhood Hits	45	Target Neighborhood Hits	86	Shared Neighborhood Hits	33
SwissProt Accessions	Q01098	Gene names	Grin2c
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 3 precursor (N-methyl D- aspartate receptor subtype 2C) (NR2C) (NMDAR2C).

NMDE4_MOUSE
NC score	0.833793 (rank : 28)	θ value	3.85808e-43 (rank : 28)
Query Neighborhood Hits	45	Target Neighborhood Hits	158	Shared Neighborhood Hits	33
SwissProt Accessions	Q03391	Gene names	Grin2d
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 4 precursor (N-methyl D- aspartate receptor subtype 2D) (NR2D) (NMDAR2D).

NMDE3_HUMAN
NC score	0.832390 (rank : 29)	θ value	8.30557e-46 (rank : 26)
Query Neighborhood Hits	45	Target Neighborhood Hits	110	Shared Neighborhood Hits	33
SwissProt Accessions	Q14957	Gene names	GRIN2C
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 3 precursor (N-methyl D- aspartate receptor subtype 2C) (NR2C) (NMDAR2C).

NMDE2_HUMAN
NC score	0.831684 (rank : 30)	θ value	1.15895e-47 (rank : 23)
Query Neighborhood Hits	45	Target Neighborhood Hits	65	Shared Neighborhood Hits	33
SwissProt Accessions	Q13224, Q12919, Q13220, Q13225, Q9UM56	Gene names	GRIN2B
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 2 precursor (N-methyl D- aspartate receptor subtype 2B) (NR2B) (NMDAR2B) (N-methyl-D-aspartate receptor subunit 3) (NR3) (hNR3).

NMDE2_MOUSE
NC score	0.831645 (rank : 31)	θ value	1.97686e-47 (rank : 24)
Query Neighborhood Hits	45	Target Neighborhood Hits	64	Shared Neighborhood Hits	33
SwissProt Accessions	Q01097, Q9DCB2	Gene names	Grin2b
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 2 precursor (N-methyl D- aspartate receptor subtype 2B) (NR2B) (NMDAR2B).

NMDE1_MOUSE
NC score	0.827156 (rank : 32)	θ value	8.59492e-43 (rank : 30)
Query Neighborhood Hits	45	Target Neighborhood Hits	84	Shared Neighborhood Hits	33
SwissProt Accessions	P35436	Gene names	Grin2a
Domain Architecture	No domain graphic available
Description	Glutamate [NMDA] receptor subunit epsilon 1 precursor (N-methyl D- aspartate receptor subtype 2A) (NR2A) (NMDAR2A).

NMDE1_HUMAN
NC score	0.827029 (rank : 33)	θ value	6.58091e-43 (rank : 29)
Query Neighborhood Hits	45	Target Neighborhood Hits	81	Shared Neighborhood Hits	33
SwissProt Accessions	Q12879, O00669	Gene names	GRIN2A
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 1 precursor (N-methyl D- aspartate receptor subtype 2A) (NR2A) (NMDAR2A) (hNR2A).

GABR1_HUMAN
NC score	0.065160 (rank : 34)	θ value	θ > 10 (rank : 47)
Query Neighborhood Hits	45	Target Neighborhood Hits	142	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UBS5, O95375, O95468, O95975, O96022, Q86W60, Q9UQQ0	Gene names	GABBR1, GPRC3A
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 1 precursor (GABA-B receptor 1) (GABA-B-R1) (Gb1).

GABR1_MOUSE
NC score	0.064980 (rank : 35)	θ value	θ > 10 (rank : 48)
Query Neighborhood Hits	45	Target Neighborhood Hits	139	Shared Neighborhood Hits	15
SwissProt Accessions	Q9WV18, Q9WU48, Q9WV15, Q9WV16, Q9WV17	Gene names	Gabbr1
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 1 precursor (GABA-B receptor 1) (GABA-B-R1) (Gb1).

ERB1_HUMAN
NC score	0.053477 (rank : 36)	θ value	θ > 10 (rank : 46)
Query Neighborhood Hits	45	Target Neighborhood Hits	23	Shared Neighborhood Hits	8
SwissProt Accessions	P60509	Gene names
Domain Architecture	No domain graphic available
Description	HERV-R(b)_3p24.3 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (HERV-R(b) Env protein) [Includes: Surface protein domain (SU); Transmembrane protein domain (TM)].

TS1R2_MOUSE
NC score	0.035096 (rank : 37)	θ value	3.0926 (rank : 42)
Query Neighborhood Hits	45	Target Neighborhood Hits	69	Shared Neighborhood Hits	9
SwissProt Accessions	Q925I4, Q923J8	Gene names	Tas1r2, Gpr71, T1r2, Tr2
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 2 precursor (G-protein coupled receptor 71) (Sweet taste receptor T1R2).

TBLX_MOUSE
NC score	0.012817 (rank : 38)	θ value	0.62314 (rank : 34)
Query Neighborhood Hits	45	Target Neighborhood Hits	335	Shared Neighborhood Hits	7
SwissProt Accessions	Q9QXE7, Q8BMM0, Q8BYQ4, Q8C0A1	Gene names	Tbl1x, Tbl1
Domain Architecture
Description	F-box-like/WD repeat protein TBL1X (Transducin beta-like 1X protein).

IF4A1_HUMAN
NC score	0.012398 (rank : 39)	θ value	3.0926 (rank : 40)
Query Neighborhood Hits	45	Target Neighborhood Hits	106	Shared Neighborhood Hits	10
SwissProt Accessions	P60842, P04765, Q5U018, Q61516	Gene names	EIF4A1, DDX2A, EIF4A
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

IF4A1_MOUSE
NC score	0.012398 (rank : 40)	θ value	3.0926 (rank : 41)
Query Neighborhood Hits	45	Target Neighborhood Hits	106	Shared Neighborhood Hits	10
SwissProt Accessions	P60843, P04765, Q61516	Gene names	Eif4a1, Ddx2a, Eif4a
Domain Architecture
Description	Eukaryotic initiation factor 4A-I (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-1) (eIF4A-I) (eIF-4A-I).

TBL1Y_HUMAN
NC score	0.012362 (rank : 41)	θ value	1.06291 (rank : 35)
Query Neighborhood Hits	45	Target Neighborhood Hits	331	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BQ87	Gene names	TBL1Y, TBL1
Domain Architecture
Description	F-box-like/WD repeat protein TBL1Y (Transducin beta-like 1Y protein) (Transducin-beta-like 1, Y-linked).

TBL1X_HUMAN
NC score	0.011971 (rank : 42)	θ value	1.38821 (rank : 39)
Query Neighborhood Hits	45	Target Neighborhood Hits	329	Shared Neighborhood Hits	7
SwissProt Accessions	O60907, Q86UY2	Gene names	TBL1X, TBL1
Domain Architecture
Description	F-box-like/WD repeat protein TBL1X (Transducin beta-like 1X protein) (Transducin-beta-like 1, X-linked) (SMAP55).

TBL1R_HUMAN
NC score	0.011707 (rank : 43)	θ value	1.38821 (rank : 37)
Query Neighborhood Hits	45	Target Neighborhood Hits	327	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BZK7, Q9H2I1, Q9H9A1	Gene names	TBL1XR1, IRA1, TBLR1
Domain Architecture
Description	F-box-like/WD repeat protein TBL1XR1 (Transducin beta-like 1X-related protein 1) (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1) (TBL1-related protein 1).

TBL1R_MOUSE
NC score	0.011698 (rank : 44)	θ value	1.38821 (rank : 38)
Query Neighborhood Hits	45	Target Neighborhood Hits	329	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BHJ5, Q3UWL6, Q8CBG4, Q8VEG3, Q9EQD4	Gene names	Tbl1xr1, Ira1, Tblr1
Domain Architecture
Description	F-box-like/WD repeat protein TBL1XR1 (Transducin beta-like 1X-related protein 1) (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1) (TBL1-related protein 1).

GUC2G_MOUSE
NC score	0.011534 (rank : 45)	θ value	1.38821 (rank : 36)
Query Neighborhood Hits	45	Target Neighborhood Hits	644	Shared Neighborhood Hits	9
SwissProt Accessions	Q6TL19, Q8BWU7	Gene names	Gucy2g
Domain Architecture	No domain graphic available
Description	Guanylate cyclase 2G precursor (EC 4.6.1.2) (Guanylyl cyclase receptor G) (mGC-G).

IF4A2_HUMAN
NC score	0.010600 (rank : 46)	θ value	5.27518 (rank : 43)
Query Neighborhood Hits	45	Target Neighborhood Hits	102	Shared Neighborhood Hits	10
SwissProt Accessions	Q14240, Q96B90, Q96EA8	Gene names	EIF4A2, DDX2B
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

IF4A2_MOUSE
NC score	0.010600 (rank : 47)	θ value	5.27518 (rank : 44)
Query Neighborhood Hits	45	Target Neighborhood Hits	102	Shared Neighborhood Hits	10
SwissProt Accessions	P10630, Q61513, Q61514	Gene names	Eif4a2, Ddx2b
Domain Architecture
Description	Eukaryotic initiation factor 4A-II (EC 3.6.1.-) (ATP-dependent RNA helicase eIF4A-2) (eIF4A-II) (eIF-4A-II).

PMVK_MOUSE
NC score	0.006289 (rank : 48)	θ value	8.99809 (rank : 45)
Query Neighborhood Hits	45	Target Neighborhood Hits	4	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D1G2, Q8R021, Q9D6K3	Gene names	Pmvk
Domain Architecture
Description	Phosphomevalonate kinase (EC 2.7.4.2) (PMKase).