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Network neighborhood for query Sequence : NMD3A_HUMAN

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NMD3A_HUMAN
SwissProt Accessions	Q8TCU5, Q8TF29, Q8WXI6	Gene names	GRIN3A, KIAA1973
Domain Architecture	No domain graphic available
Description	Glutamate [NMDA] receptor subunit 3A precursor (N-methyl-D-aspartate receptor subtype NR3A) (NMDAR-L).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

NMD3A_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	58	Target Neighborhood Hits	58	Shared Neighborhood Hits	58
SwissProt Accessions	Q8TCU5, Q8TF29, Q8WXI6	Gene names	GRIN3A, KIAA1973
Domain Architecture	No domain graphic available
Description	Glutamate [NMDA] receptor subunit 3A precursor (N-methyl-D-aspartate receptor subtype NR3A) (NMDAR-L).

NMD3B_HUMAN
θ value	0 (rank : 2)	NC score	0.993813 (rank : 2)
Query Neighborhood Hits	58	Target Neighborhood Hits	55	Shared Neighborhood Hits	36
SwissProt Accessions	O60391, Q5EAK7, Q7RTW9	Gene names	GRIN3B
Domain Architecture	No domain graphic available
Description	Glutamate [NMDA] receptor subunit 3B precursor (N-methyl-D-aspartate receptor subtype NR3B) (NR3B) (NMDAR3B).

NMD3B_MOUSE
θ value	0 (rank : 3)	NC score	0.993550 (rank : 3)
Query Neighborhood Hits	58	Target Neighborhood Hits	51	Shared Neighborhood Hits	34
SwissProt Accessions	Q91ZU9, Q8VHV0	Gene names	Grin3b
Domain Architecture	No domain graphic available
Description	Glutamate [NMDA] receptor subunit 3B precursor (N-methyl-D-aspartate receptor subunit NR3B) (NR3B) (NMDAR3B) (NMDA receptor NR4) (Nr4).

NMDE1_MOUSE
θ value	2.47191e-82 (rank : 4)	NC score	0.933847 (rank : 9)
Query Neighborhood Hits	58	Target Neighborhood Hits	84	Shared Neighborhood Hits	33
SwissProt Accessions	P35436	Gene names	Grin2a
Domain Architecture	No domain graphic available
Description	Glutamate [NMDA] receptor subunit epsilon 1 precursor (N-methyl D- aspartate receptor subtype 2A) (NR2A) (NMDAR2A).

NMDE2_MOUSE
θ value	4.21644e-82 (rank : 5)	NC score	0.934831 (rank : 6)
Query Neighborhood Hits	58	Target Neighborhood Hits	64	Shared Neighborhood Hits	35
SwissProt Accessions	Q01097, Q9DCB2	Gene names	Grin2b
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 2 precursor (N-methyl D- aspartate receptor subtype 2B) (NR2B) (NMDAR2B).

NMDE2_HUMAN
θ value	9.39325e-82 (rank : 6)	NC score	0.934870 (rank : 5)
Query Neighborhood Hits	58	Target Neighborhood Hits	65	Shared Neighborhood Hits	35
SwissProt Accessions	Q13224, Q12919, Q13220, Q13225, Q9UM56	Gene names	GRIN2B
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 2 precursor (N-methyl D- aspartate receptor subtype 2B) (NR2B) (NMDAR2B) (N-methyl-D-aspartate receptor subunit 3) (NR3) (hNR3).

NMDE1_HUMAN
θ value	7.95186e-81 (rank : 7)	NC score	0.933090 (rank : 10)
Query Neighborhood Hits	58	Target Neighborhood Hits	81	Shared Neighborhood Hits	33
SwissProt Accessions	Q12879, O00669	Gene names	GRIN2A
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 1 precursor (N-methyl D- aspartate receptor subtype 2A) (NR2A) (NMDAR2A) (hNR2A).

NMDE4_HUMAN
θ value	1.11217e-74 (rank : 8)	NC score	0.935385 (rank : 4)
Query Neighborhood Hits	58	Target Neighborhood Hits	133	Shared Neighborhood Hits	35
SwissProt Accessions	O15399	Gene names	GRIN2D
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 4 precursor (N-methyl D- aspartate receptor subtype 2D) (NR2D) (NMDAR2D) (EB11).

NMDE4_MOUSE
θ value	1.11217e-74 (rank : 9)	NC score	0.932969 (rank : 11)
Query Neighborhood Hits	58	Target Neighborhood Hits	158	Shared Neighborhood Hits	35
SwissProt Accessions	Q03391	Gene names	Grin2d
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 4 precursor (N-methyl D- aspartate receptor subtype 2D) (NR2D) (NMDAR2D).

NMDE3_MOUSE
θ value	2.56397e-71 (rank : 10)	NC score	0.934229 (rank : 7)
Query Neighborhood Hits	58	Target Neighborhood Hits	86	Shared Neighborhood Hits	34
SwissProt Accessions	Q01098	Gene names	Grin2c
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 3 precursor (N-methyl D- aspartate receptor subtype 2C) (NR2C) (NMDAR2C).

NMDE3_HUMAN
θ value	2.17053e-70 (rank : 11)	NC score	0.934014 (rank : 8)
Query Neighborhood Hits	58	Target Neighborhood Hits	110	Shared Neighborhood Hits	34
SwissProt Accessions	Q14957	Gene names	GRIN2C
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 3 precursor (N-methyl D- aspartate receptor subtype 2C) (NR2C) (NMDAR2C).

NMDZ1_HUMAN
θ value	2.24614e-67 (rank : 12)	NC score	0.926388 (rank : 12)
Query Neighborhood Hits	58	Target Neighborhood Hits	77	Shared Neighborhood Hits	36
SwissProt Accessions	Q05586, P35437, Q12867, Q12868	Gene names	GRIN1, NMDAR1
Domain Architecture
Description	Glutamate [NMDA] receptor subunit zeta 1 precursor (N-methyl-D- aspartate receptor subunit NR1).

NMDZ1_MOUSE
θ value	2.24614e-67 (rank : 13)	NC score	0.926014 (rank : 13)
Query Neighborhood Hits	58	Target Neighborhood Hits	76	Shared Neighborhood Hits	36
SwissProt Accessions	P35438, Q8CFS4	Gene names	Grin1, Glurz1
Domain Architecture
Description	Glutamate [NMDA] receptor subunit zeta 1 precursor (N-methyl-D- aspartate receptor subunit NR1).

GRIK1_HUMAN
θ value	2.34062e-40 (rank : 14)	NC score	0.869494 (rank : 16)
Query Neighborhood Hits	58	Target Neighborhood Hits	48	Shared Neighborhood Hits	35
SwissProt Accessions	P39086, Q13001, Q86SU9	Gene names	GRIK1, GLUR5
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 1 precursor (Glutamate receptor 5) (GluR-5) (GluR5) (Excitatory amino acid receptor 3) (EAA3).

GRIK2_HUMAN
θ value	7.52953e-39 (rank : 15)	NC score	0.867985 (rank : 18)
Query Neighborhood Hits	58	Target Neighborhood Hits	50	Shared Neighborhood Hits	36
SwissProt Accessions	Q13002	Gene names	GRIK2, GLUR6
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 2 precursor (Glutamate receptor 6) (GluR-6) (GluR6) (Excitatory amino acid receptor 4) (EAA4).

GRIA1_MOUSE
θ value	2.86122e-38 (rank : 16)	NC score	0.862064 (rank : 25)
Query Neighborhood Hits	58	Target Neighborhood Hits	46	Shared Neighborhood Hits	33
SwissProt Accessions	P23818	Gene names	Gria1, Glur1
Domain Architecture
Description	Glutamate receptor 1 precursor (GluR-1) (GluR-A) (GluR-K1) (Glutamate receptor ionotropic, AMPA 1) (AMPA-selective glutamate receptor 1).

GRIK3_HUMAN
θ value	4.88048e-38 (rank : 17)	NC score	0.868454 (rank : 17)
Query Neighborhood Hits	58	Target Neighborhood Hits	41	Shared Neighborhood Hits	36
SwissProt Accessions	Q13003, Q13004, Q16136	Gene names	GRIK3, GLUR7
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 3 precursor (Glutamate receptor 7) (GluR-7) (GluR7) (Excitatory amino acid receptor 5) (EAA5).

GRIA2_HUMAN
θ value	1.42001e-37 (rank : 18)	NC score	0.858111 (rank : 28)
Query Neighborhood Hits	58	Target Neighborhood Hits	47	Shared Neighborhood Hits	33
SwissProt Accessions	P42262, Q96FP6	Gene names	GRIA2, GLUR2
Domain Architecture
Description	Glutamate receptor 2 precursor (GluR-2) (GluR-B) (GluR-K2) (Glutamate receptor ionotropic, AMPA 2) (AMPA-selective glutamate receptor 2).

GRIA2_MOUSE
θ value	1.85459e-37 (rank : 19)	NC score	0.857629 (rank : 29)
Query Neighborhood Hits	58	Target Neighborhood Hits	47	Shared Neighborhood Hits	33
SwissProt Accessions	P23819, Q61604, Q61605, Q8BG69, Q8BXU3, Q9D6D3	Gene names	Gria2, Glur2
Domain Architecture
Description	Glutamate receptor 2 precursor (GluR-2) (GluR-B) (GluR-K2) (Glutamate receptor ionotropic, AMPA 2) (AMPA-selective glutamate receptor 2).

GRIA3_MOUSE
θ value	2.42216e-37 (rank : 20)	NC score	0.858443 (rank : 27)
Query Neighborhood Hits	58	Target Neighborhood Hits	39	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Z2W9, Q5DTJ0	Gene names	Gria3, Glur3, Kiaa4184
Domain Architecture	No domain graphic available
Description	Glutamate receptor 3 precursor (GluR-3) (GluR-C) (GluR-K3) (Glutamate receptor ionotropic, AMPA 3) (AMPA-selective glutamate receptor 3).

GRIA1_HUMAN
θ value	3.16345e-37 (rank : 21)	NC score	0.860931 (rank : 26)
Query Neighborhood Hits	58	Target Neighborhood Hits	45	Shared Neighborhood Hits	33
SwissProt Accessions	P42261	Gene names	GRIA1, GLUH1, GLUR1
Domain Architecture
Description	Glutamate receptor 1 precursor (GluR-1) (GluR-A) (GluR-K1) (Glutamate receptor ionotropic, AMPA 1) (AMPA-selective glutamate receptor 1).

GRID2_HUMAN
θ value	9.20422e-37 (rank : 22)	NC score	0.870096 (rank : 15)
Query Neighborhood Hits	58	Target Neighborhood Hits	48	Shared Neighborhood Hits	33
SwissProt Accessions	O43424	Gene names	GRID2, GLURD2
Domain Architecture
Description	Glutamate receptor delta-2 subunit precursor (GluR delta-2).

GRIA3_HUMAN
θ value	3.4976e-36 (rank : 23)	NC score	0.857291 (rank : 30)
Query Neighborhood Hits	58	Target Neighborhood Hits	40	Shared Neighborhood Hits	33
SwissProt Accessions	P42263, Q4VXD5, Q4VXD6, Q9HDA0, Q9HDA1, Q9HDA2	Gene names	GRIA3, GLUR3, GLURC
Domain Architecture
Description	Glutamate receptor 3 precursor (GluR-3) (GluR-C) (GluR-K3) (Glutamate receptor ionotropic, AMPA 3) (AMPA-selective glutamate receptor 3).

GRIA4_HUMAN
θ value	1.32909e-35 (rank : 24)	NC score	0.857224 (rank : 31)
Query Neighborhood Hits	58	Target Neighborhood Hits	45	Shared Neighborhood Hits	33
SwissProt Accessions	P48058	Gene names	GRIA4, GLUR4
Domain Architecture
Description	Glutamate receptor 4 precursor (GluR-4) (GluR4) (GluR-D) (Glutamate receptor ionotropic, AMPA 4) (AMPA-selective glutamate receptor 4).

GRID2_MOUSE
θ value	1.73584e-35 (rank : 25)	NC score	0.870440 (rank : 14)
Query Neighborhood Hits	58	Target Neighborhood Hits	44	Shared Neighborhood Hits	33
SwissProt Accessions	Q61625	Gene names	Grid2
Domain Architecture
Description	Glutamate receptor delta-2 subunit precursor (GluR delta-2).

GRIK4_MOUSE
θ value	2.26708e-35 (rank : 26)	NC score	0.866766 (rank : 21)
Query Neighborhood Hits	58	Target Neighborhood Hits	41	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BMF5	Gene names	Grik4
Domain Architecture	No domain graphic available
Description	Glutamate receptor, ionotropic kainate 4 precursor.

GRIK5_MOUSE
θ value	2.96089e-35 (rank : 27)	NC score	0.865538 (rank : 23)
Query Neighborhood Hits	58	Target Neighborhood Hits	47	Shared Neighborhood Hits	34
SwissProt Accessions	Q61626	Gene names	Grik5
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 5 precursor (Glutamate receptor KA-2) (KA2) (Glutamate receptor gamma-2) (GluR gamma-2).

GRIK4_HUMAN
θ value	3.86705e-35 (rank : 28)	NC score	0.866929 (rank : 20)
Query Neighborhood Hits	58	Target Neighborhood Hits	42	Shared Neighborhood Hits	34
SwissProt Accessions	Q16099	Gene names	GRIK4, GRIK
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 4 precursor (Glutamate receptor KA-1) (KA1) (Excitatory amino acid receptor 1) (EAA1).

GRIK5_HUMAN
θ value	6.59618e-35 (rank : 29)	NC score	0.866161 (rank : 22)
Query Neighborhood Hits	58	Target Neighborhood Hits	44	Shared Neighborhood Hits	34
SwissProt Accessions	Q16478	Gene names	GRIK5, GRIK2
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 5 precursor (Glutamate receptor KA-2) (KA2) (Excitatory amino acid receptor 2) (EAA2).

GRIA4_MOUSE
θ value	7.29293e-34 (rank : 30)	NC score	0.854638 (rank : 32)
Query Neighborhood Hits	58	Target Neighborhood Hits	44	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Z2W8	Gene names	Gria4, Glur4
Domain Architecture
Description	Glutamate receptor 4 precursor (GluR-4) (GluR4) (GluR-D) (Glutamate receptor ionotropic, AMPA 4) (AMPA-selective glutamate receptor 4).

GRID1_MOUSE
θ value	1.0531e-32 (rank : 31)	NC score	0.867101 (rank : 19)
Query Neighborhood Hits	58	Target Neighborhood Hits	42	Shared Neighborhood Hits	33
SwissProt Accessions	Q61627	Gene names	Grid1
Domain Architecture
Description	Glutamate receptor delta-1 subunit precursor (GluR delta-1).

GRID1_HUMAN
θ value	3.06405e-32 (rank : 32)	NC score	0.865510 (rank : 24)
Query Neighborhood Hits	58	Target Neighborhood Hits	42	Shared Neighborhood Hits	33
SwissProt Accessions	Q9ULK0, Q8IXT3	Gene names	GRID1, KIAA1220
Domain Architecture
Description	Glutamate receptor delta-1 subunit precursor (GluR delta-1).

GRIK1_MOUSE
θ value	3.07116e-24 (rank : 33)	NC score	0.849246 (rank : 33)
Query Neighborhood Hits	58	Target Neighborhood Hits	46	Shared Neighborhood Hits	35
SwissProt Accessions	Q60934	Gene names	Grik1, Glur5
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 1 precursor (Glutamate receptor 5) (GluR-5) (GluR5).

MGR1_HUMAN
θ value	0.365318 (rank : 34)	NC score	0.039417 (rank : 38)
Query Neighborhood Hits	58	Target Neighborhood Hits	85	Shared Neighborhood Hits	13
SwissProt Accessions	Q13255, Q13256, Q14757, Q14758, Q5VTF7, Q5VTF8, Q9NU10, Q9UGS9, Q9UGT0	Gene names	GRM1, GPRC1A, MGLUR1
Domain Architecture
Description	Metabotropic glutamate receptor 1 precursor (mGluR1).

MGR1_MOUSE
θ value	0.365318 (rank : 35)	NC score	0.039432 (rank : 37)
Query Neighborhood Hits	58	Target Neighborhood Hits	90	Shared Neighborhood Hits	13
SwissProt Accessions	P97772, Q6AXG4, Q9EPV6	Gene names	Grm1, Gprc1a, Mglur1
Domain Architecture
Description	Metabotropic glutamate receptor 1 precursor (mGluR1).

TLR8_MOUSE
θ value	0.47712 (rank : 36)	NC score	0.005341 (rank : 51)
Query Neighborhood Hits	58	Target Neighborhood Hits	297	Shared Neighborhood Hits	2
SwissProt Accessions	P58682, Q91XI7	Gene names	Tlr8
Domain Architecture
Description	Toll-like receptor 8 precursor.

CCD46_HUMAN
θ value	0.813845 (rank : 37)	NC score	0.001214 (rank : 57)
Query Neighborhood Hits	58	Target Neighborhood Hits	1430	Shared Neighborhood Hits	7
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

DIDO1_HUMAN
θ value	1.38821 (rank : 38)	NC score	0.010776 (rank : 44)
Query Neighborhood Hits	58	Target Neighborhood Hits	960	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

IF_HUMAN
θ value	1.38821 (rank : 39)	NC score	0.016316 (rank : 40)
Query Neighborhood Hits	58	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	P27352	Gene names	GIF, IFMH
Domain Architecture
Description	Gastric intrinsic factor precursor (Intrinsic factor) (IF) (INF).

EEA1_HUMAN
θ value	2.36792 (rank : 40)	NC score	-0.000907 (rank : 58)
Query Neighborhood Hits	58	Target Neighborhood Hits	1796	Shared Neighborhood Hits	11
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

CTL3_MOUSE
θ value	3.0926 (rank : 41)	NC score	0.010856 (rank : 43)
Query Neighborhood Hits	58	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	Q921V7	Gene names	Slc44a3, Ctl3
Domain Architecture	No domain graphic available
Description	Choline transporter-like protein 3 (Solute carrier family 44 member 3).

DIAP3_HUMAN
θ value	3.0926 (rank : 42)	NC score	0.015305 (rank : 42)
Query Neighborhood Hits	58	Target Neighborhood Hits	209	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NSV4, Q5T2S7, Q5XKF6, Q6MZF0, Q6NUP0, Q86VS4, Q8NAV4	Gene names	DIAPH3, DIAP3
Domain Architecture	No domain graphic available
Description	Protein diaphanous homolog 3 (Diaphanous-related formin-3) (DRF3).

MGR4_HUMAN
θ value	3.0926 (rank : 43)	NC score	0.026669 (rank : 39)
Query Neighborhood Hits	58	Target Neighborhood Hits	63	Shared Neighborhood Hits	10
SwissProt Accessions	Q14833, Q5SZ84	Gene names	GRM4, GPRC1D, MGLUR4
Domain Architecture
Description	Metabotropic glutamate receptor 4 precursor (mGluR4).

HOOK1_HUMAN
θ value	4.03905 (rank : 44)	NC score	0.001455 (rank : 56)
Query Neighborhood Hits	58	Target Neighborhood Hits	942	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UJC3, O60561, Q5TG44	Gene names	HOOK1
Domain Architecture
Description	Hook homolog 1 (h-hook1) (hHK1).

TPR_HUMAN
θ value	4.03905 (rank : 45)	NC score	-0.001577 (rank : 59)
Query Neighborhood Hits	58	Target Neighborhood Hits	1921	Shared Neighborhood Hits	10
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

CTL3_HUMAN
θ value	5.27518 (rank : 46)	NC score	0.009626 (rank : 45)
Query Neighborhood Hits	58	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N4M1, Q6UWT1, Q9BWY7	Gene names	SLC44A3, CTL3
Domain Architecture	No domain graphic available
Description	Choline transporter-like protein 3 (Solute carrier family 44 member 3).

FZD8_HUMAN
θ value	5.27518 (rank : 47)	NC score	0.003625 (rank : 52)
Query Neighborhood Hits	58	Target Neighborhood Hits	88	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H461	Gene names	FZD8
Domain Architecture
Description	Frizzled-8 precursor (Fz-8) (hFz8).

GO45_HUMAN
θ value	5.27518 (rank : 48)	NC score	0.008537 (rank : 46)
Query Neighborhood Hits	58	Target Neighborhood Hits	189	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H2G9, O15298, Q5T531, Q9GZX4	Gene names	BLZF1, JEM1
Domain Architecture	No domain graphic available
Description	Golgin 45 (Basic leucine zipper nuclear factor 1) (JEM-1) (p45 basic leucine-zipper nuclear factor).

RIN1_HUMAN
θ value	5.27518 (rank : 49)	NC score	0.007438 (rank : 48)
Query Neighborhood Hits	58	Target Neighborhood Hits	52	Shared Neighborhood Hits	2
SwissProt Accessions	Q13671, O15010, Q00427, Q96CC8	Gene names	RIN1
Domain Architecture
Description	Ras and Rab interactor 1 (Ras interaction/interference protein 1) (Ras inhibitor JC99).

TRAF3_HUMAN
θ value	5.27518 (rank : 50)	NC score	0.005786 (rank : 49)
Query Neighborhood Hits	58	Target Neighborhood Hits	463	Shared Neighborhood Hits	6
SwissProt Accessions	Q13114, Q12990, Q13076, Q13947, Q6AZX1, Q9UNL1	Gene names	TRAF3, CAP1, CRAF1
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein) (LAP1) (CAP-1).

TRAF3_MOUSE
θ value	5.27518 (rank : 51)	NC score	0.005747 (rank : 50)
Query Neighborhood Hits	58	Target Neighborhood Hits	476	Shared Neighborhood Hits	6
SwissProt Accessions	Q60803, Q62380	Gene names	Traf3, Craf1, Trafamn
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (TRAFAMN).

ACD_HUMAN
θ value	6.88961 (rank : 52)	NC score	0.008140 (rank : 47)
Query Neighborhood Hits	58	Target Neighborhood Hits	143	Shared Neighborhood Hits	2
SwissProt Accessions	Q96AP0, Q562H5, Q9H8F9	Gene names	ACD, PIP1, PTOP
Domain Architecture	No domain graphic available
Description	Adrenocortical dysplasia protein homolog (POT1 and TIN2-interacting protein).

ALK_MOUSE
θ value	8.99809 (rank : 53)	NC score	-0.003728 (rank : 61)
Query Neighborhood Hits	58	Target Neighborhood Hits	811	Shared Neighborhood Hits	2
SwissProt Accessions	P97793	Gene names	Alk
Domain Architecture
Description	ALK tyrosine kinase receptor precursor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD246 antigen).

ARSD_HUMAN
θ value	8.99809 (rank : 54)	NC score	0.003226 (rank : 53)
Query Neighborhood Hits	58	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	P51689, Q9UHJ8	Gene names	ARSD
Domain Architecture
Description	Arylsulfatase D precursor (EC 3.1.6.-) (ASD).

FZD8_MOUSE
θ value	8.99809 (rank : 55)	NC score	0.003024 (rank : 54)
Query Neighborhood Hits	58	Target Neighborhood Hits	89	Shared Neighborhood Hits	4
SwissProt Accessions	Q61091	Gene names	Fzd8
Domain Architecture
Description	Frizzled-8 precursor (Fz-8) (mFz8).

GOGB1_HUMAN
θ value	8.99809 (rank : 56)	NC score	-0.002962 (rank : 60)
Query Neighborhood Hits	58	Target Neighborhood Hits	2297	Shared Neighborhood Hits	12
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

JIP3_HUMAN
θ value	8.99809 (rank : 57)	NC score	0.002593 (rank : 55)
Query Neighborhood Hits	58	Target Neighborhood Hits	1039	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

PSL1_HUMAN
θ value	8.99809 (rank : 58)	NC score	0.016312 (rank : 41)
Query Neighborhood Hits	58	Target Neighborhood Hits	650	Shared Neighborhood Hits	8
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

ERB1_HUMAN
θ value	θ > 10 (rank : 59)	NC score	0.087530 (rank : 34)
Query Neighborhood Hits	58	Target Neighborhood Hits	23	Shared Neighborhood Hits	8
SwissProt Accessions	P60509	Gene names
Domain Architecture	No domain graphic available
Description	HERV-R(b)_3p24.3 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (HERV-R(b) Env protein) [Includes: Surface protein domain (SU); Transmembrane protein domain (TM)].

GABR1_HUMAN
θ value	θ > 10 (rank : 60)	NC score	0.051155 (rank : 35)
Query Neighborhood Hits	58	Target Neighborhood Hits	142	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UBS5, O95375, O95468, O95975, O96022, Q86W60, Q9UQQ0	Gene names	GABBR1, GPRC3A
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 1 precursor (GABA-B receptor 1) (GABA-B-R1) (Gb1).

GABR1_MOUSE
θ value	θ > 10 (rank : 61)	NC score	0.051042 (rank : 36)
Query Neighborhood Hits	58	Target Neighborhood Hits	139	Shared Neighborhood Hits	18
SwissProt Accessions	Q9WV18, Q9WU48, Q9WV15, Q9WV16, Q9WV17	Gene names	Gabbr1
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 1 precursor (GABA-B receptor 1) (GABA-B-R1) (Gb1).

Hits sorted by NC score

NMD3A_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	58	Target Neighborhood Hits	58	Shared Neighborhood Hits	58
SwissProt Accessions	Q8TCU5, Q8TF29, Q8WXI6	Gene names	GRIN3A, KIAA1973
Domain Architecture	No domain graphic available
Description	Glutamate [NMDA] receptor subunit 3A precursor (N-methyl-D-aspartate receptor subtype NR3A) (NMDAR-L).

NMD3B_HUMAN
NC score	0.993813 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	58	Target Neighborhood Hits	55	Shared Neighborhood Hits	36
SwissProt Accessions	O60391, Q5EAK7, Q7RTW9	Gene names	GRIN3B
Domain Architecture	No domain graphic available
Description	Glutamate [NMDA] receptor subunit 3B precursor (N-methyl-D-aspartate receptor subtype NR3B) (NR3B) (NMDAR3B).

NMD3B_MOUSE
NC score	0.993550 (rank : 3)	θ value	0 (rank : 3)
Query Neighborhood Hits	58	Target Neighborhood Hits	51	Shared Neighborhood Hits	34
SwissProt Accessions	Q91ZU9, Q8VHV0	Gene names	Grin3b
Domain Architecture	No domain graphic available
Description	Glutamate [NMDA] receptor subunit 3B precursor (N-methyl-D-aspartate receptor subunit NR3B) (NR3B) (NMDAR3B) (NMDA receptor NR4) (Nr4).

NMDE4_HUMAN
NC score	0.935385 (rank : 4)	θ value	1.11217e-74 (rank : 8)
Query Neighborhood Hits	58	Target Neighborhood Hits	133	Shared Neighborhood Hits	35
SwissProt Accessions	O15399	Gene names	GRIN2D
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 4 precursor (N-methyl D- aspartate receptor subtype 2D) (NR2D) (NMDAR2D) (EB11).

NMDE2_HUMAN
NC score	0.934870 (rank : 5)	θ value	9.39325e-82 (rank : 6)
Query Neighborhood Hits	58	Target Neighborhood Hits	65	Shared Neighborhood Hits	35
SwissProt Accessions	Q13224, Q12919, Q13220, Q13225, Q9UM56	Gene names	GRIN2B
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 2 precursor (N-methyl D- aspartate receptor subtype 2B) (NR2B) (NMDAR2B) (N-methyl-D-aspartate receptor subunit 3) (NR3) (hNR3).

NMDE2_MOUSE
NC score	0.934831 (rank : 6)	θ value	4.21644e-82 (rank : 5)
Query Neighborhood Hits	58	Target Neighborhood Hits	64	Shared Neighborhood Hits	35
SwissProt Accessions	Q01097, Q9DCB2	Gene names	Grin2b
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 2 precursor (N-methyl D- aspartate receptor subtype 2B) (NR2B) (NMDAR2B).

NMDE3_MOUSE
NC score	0.934229 (rank : 7)	θ value	2.56397e-71 (rank : 10)
Query Neighborhood Hits	58	Target Neighborhood Hits	86	Shared Neighborhood Hits	34
SwissProt Accessions	Q01098	Gene names	Grin2c
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 3 precursor (N-methyl D- aspartate receptor subtype 2C) (NR2C) (NMDAR2C).

NMDE3_HUMAN
NC score	0.934014 (rank : 8)	θ value	2.17053e-70 (rank : 11)
Query Neighborhood Hits	58	Target Neighborhood Hits	110	Shared Neighborhood Hits	34
SwissProt Accessions	Q14957	Gene names	GRIN2C
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 3 precursor (N-methyl D- aspartate receptor subtype 2C) (NR2C) (NMDAR2C).

NMDE1_MOUSE
NC score	0.933847 (rank : 9)	θ value	2.47191e-82 (rank : 4)
Query Neighborhood Hits	58	Target Neighborhood Hits	84	Shared Neighborhood Hits	33
SwissProt Accessions	P35436	Gene names	Grin2a
Domain Architecture	No domain graphic available
Description	Glutamate [NMDA] receptor subunit epsilon 1 precursor (N-methyl D- aspartate receptor subtype 2A) (NR2A) (NMDAR2A).

NMDE1_HUMAN
NC score	0.933090 (rank : 10)	θ value	7.95186e-81 (rank : 7)
Query Neighborhood Hits	58	Target Neighborhood Hits	81	Shared Neighborhood Hits	33
SwissProt Accessions	Q12879, O00669	Gene names	GRIN2A
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 1 precursor (N-methyl D- aspartate receptor subtype 2A) (NR2A) (NMDAR2A) (hNR2A).

NMDE4_MOUSE
NC score	0.932969 (rank : 11)	θ value	1.11217e-74 (rank : 9)
Query Neighborhood Hits	58	Target Neighborhood Hits	158	Shared Neighborhood Hits	35
SwissProt Accessions	Q03391	Gene names	Grin2d
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 4 precursor (N-methyl D- aspartate receptor subtype 2D) (NR2D) (NMDAR2D).

NMDZ1_HUMAN
NC score	0.926388 (rank : 12)	θ value	2.24614e-67 (rank : 12)
Query Neighborhood Hits	58	Target Neighborhood Hits	77	Shared Neighborhood Hits	36
SwissProt Accessions	Q05586, P35437, Q12867, Q12868	Gene names	GRIN1, NMDAR1
Domain Architecture
Description	Glutamate [NMDA] receptor subunit zeta 1 precursor (N-methyl-D- aspartate receptor subunit NR1).

NMDZ1_MOUSE
NC score	0.926014 (rank : 13)	θ value	2.24614e-67 (rank : 13)
Query Neighborhood Hits	58	Target Neighborhood Hits	76	Shared Neighborhood Hits	36
SwissProt Accessions	P35438, Q8CFS4	Gene names	Grin1, Glurz1
Domain Architecture
Description	Glutamate [NMDA] receptor subunit zeta 1 precursor (N-methyl-D- aspartate receptor subunit NR1).

GRID2_MOUSE
NC score	0.870440 (rank : 14)	θ value	1.73584e-35 (rank : 25)
Query Neighborhood Hits	58	Target Neighborhood Hits	44	Shared Neighborhood Hits	33
SwissProt Accessions	Q61625	Gene names	Grid2
Domain Architecture
Description	Glutamate receptor delta-2 subunit precursor (GluR delta-2).

GRID2_HUMAN
NC score	0.870096 (rank : 15)	θ value	9.20422e-37 (rank : 22)
Query Neighborhood Hits	58	Target Neighborhood Hits	48	Shared Neighborhood Hits	33
SwissProt Accessions	O43424	Gene names	GRID2, GLURD2
Domain Architecture
Description	Glutamate receptor delta-2 subunit precursor (GluR delta-2).

GRIK1_HUMAN
NC score	0.869494 (rank : 16)	θ value	2.34062e-40 (rank : 14)
Query Neighborhood Hits	58	Target Neighborhood Hits	48	Shared Neighborhood Hits	35
SwissProt Accessions	P39086, Q13001, Q86SU9	Gene names	GRIK1, GLUR5
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 1 precursor (Glutamate receptor 5) (GluR-5) (GluR5) (Excitatory amino acid receptor 3) (EAA3).

GRIK3_HUMAN
NC score	0.868454 (rank : 17)	θ value	4.88048e-38 (rank : 17)
Query Neighborhood Hits	58	Target Neighborhood Hits	41	Shared Neighborhood Hits	36
SwissProt Accessions	Q13003, Q13004, Q16136	Gene names	GRIK3, GLUR7
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 3 precursor (Glutamate receptor 7) (GluR-7) (GluR7) (Excitatory amino acid receptor 5) (EAA5).

GRIK2_HUMAN
NC score	0.867985 (rank : 18)	θ value	7.52953e-39 (rank : 15)
Query Neighborhood Hits	58	Target Neighborhood Hits	50	Shared Neighborhood Hits	36
SwissProt Accessions	Q13002	Gene names	GRIK2, GLUR6
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 2 precursor (Glutamate receptor 6) (GluR-6) (GluR6) (Excitatory amino acid receptor 4) (EAA4).

GRID1_MOUSE
NC score	0.867101 (rank : 19)	θ value	1.0531e-32 (rank : 31)
Query Neighborhood Hits	58	Target Neighborhood Hits	42	Shared Neighborhood Hits	33
SwissProt Accessions	Q61627	Gene names	Grid1
Domain Architecture
Description	Glutamate receptor delta-1 subunit precursor (GluR delta-1).

GRIK4_HUMAN
NC score	0.866929 (rank : 20)	θ value	3.86705e-35 (rank : 28)
Query Neighborhood Hits	58	Target Neighborhood Hits	42	Shared Neighborhood Hits	34
SwissProt Accessions	Q16099	Gene names	GRIK4, GRIK
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 4 precursor (Glutamate receptor KA-1) (KA1) (Excitatory amino acid receptor 1) (EAA1).

GRIK4_MOUSE
NC score	0.866766 (rank : 21)	θ value	2.26708e-35 (rank : 26)
Query Neighborhood Hits	58	Target Neighborhood Hits	41	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BMF5	Gene names	Grik4
Domain Architecture	No domain graphic available
Description	Glutamate receptor, ionotropic kainate 4 precursor.

GRIK5_HUMAN
NC score	0.866161 (rank : 22)	θ value	6.59618e-35 (rank : 29)
Query Neighborhood Hits	58	Target Neighborhood Hits	44	Shared Neighborhood Hits	34
SwissProt Accessions	Q16478	Gene names	GRIK5, GRIK2
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 5 precursor (Glutamate receptor KA-2) (KA2) (Excitatory amino acid receptor 2) (EAA2).

GRIK5_MOUSE
NC score	0.865538 (rank : 23)	θ value	2.96089e-35 (rank : 27)
Query Neighborhood Hits	58	Target Neighborhood Hits	47	Shared Neighborhood Hits	34
SwissProt Accessions	Q61626	Gene names	Grik5
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 5 precursor (Glutamate receptor KA-2) (KA2) (Glutamate receptor gamma-2) (GluR gamma-2).

GRID1_HUMAN
NC score	0.865510 (rank : 24)	θ value	3.06405e-32 (rank : 32)
Query Neighborhood Hits	58	Target Neighborhood Hits	42	Shared Neighborhood Hits	33
SwissProt Accessions	Q9ULK0, Q8IXT3	Gene names	GRID1, KIAA1220
Domain Architecture
Description	Glutamate receptor delta-1 subunit precursor (GluR delta-1).

GRIA1_MOUSE
NC score	0.862064 (rank : 25)	θ value	2.86122e-38 (rank : 16)
Query Neighborhood Hits	58	Target Neighborhood Hits	46	Shared Neighborhood Hits	33
SwissProt Accessions	P23818	Gene names	Gria1, Glur1
Domain Architecture
Description	Glutamate receptor 1 precursor (GluR-1) (GluR-A) (GluR-K1) (Glutamate receptor ionotropic, AMPA 1) (AMPA-selective glutamate receptor 1).

GRIA1_HUMAN
NC score	0.860931 (rank : 26)	θ value	3.16345e-37 (rank : 21)
Query Neighborhood Hits	58	Target Neighborhood Hits	45	Shared Neighborhood Hits	33
SwissProt Accessions	P42261	Gene names	GRIA1, GLUH1, GLUR1
Domain Architecture
Description	Glutamate receptor 1 precursor (GluR-1) (GluR-A) (GluR-K1) (Glutamate receptor ionotropic, AMPA 1) (AMPA-selective glutamate receptor 1).

GRIA3_MOUSE
NC score	0.858443 (rank : 27)	θ value	2.42216e-37 (rank : 20)
Query Neighborhood Hits	58	Target Neighborhood Hits	39	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Z2W9, Q5DTJ0	Gene names	Gria3, Glur3, Kiaa4184
Domain Architecture	No domain graphic available
Description	Glutamate receptor 3 precursor (GluR-3) (GluR-C) (GluR-K3) (Glutamate receptor ionotropic, AMPA 3) (AMPA-selective glutamate receptor 3).

GRIA2_HUMAN
NC score	0.858111 (rank : 28)	θ value	1.42001e-37 (rank : 18)
Query Neighborhood Hits	58	Target Neighborhood Hits	47	Shared Neighborhood Hits	33
SwissProt Accessions	P42262, Q96FP6	Gene names	GRIA2, GLUR2
Domain Architecture
Description	Glutamate receptor 2 precursor (GluR-2) (GluR-B) (GluR-K2) (Glutamate receptor ionotropic, AMPA 2) (AMPA-selective glutamate receptor 2).

GRIA2_MOUSE
NC score	0.857629 (rank : 29)	θ value	1.85459e-37 (rank : 19)
Query Neighborhood Hits	58	Target Neighborhood Hits	47	Shared Neighborhood Hits	33
SwissProt Accessions	P23819, Q61604, Q61605, Q8BG69, Q8BXU3, Q9D6D3	Gene names	Gria2, Glur2
Domain Architecture
Description	Glutamate receptor 2 precursor (GluR-2) (GluR-B) (GluR-K2) (Glutamate receptor ionotropic, AMPA 2) (AMPA-selective glutamate receptor 2).

GRIA3_HUMAN
NC score	0.857291 (rank : 30)	θ value	3.4976e-36 (rank : 23)
Query Neighborhood Hits	58	Target Neighborhood Hits	40	Shared Neighborhood Hits	33
SwissProt Accessions	P42263, Q4VXD5, Q4VXD6, Q9HDA0, Q9HDA1, Q9HDA2	Gene names	GRIA3, GLUR3, GLURC
Domain Architecture
Description	Glutamate receptor 3 precursor (GluR-3) (GluR-C) (GluR-K3) (Glutamate receptor ionotropic, AMPA 3) (AMPA-selective glutamate receptor 3).

GRIA4_HUMAN
NC score	0.857224 (rank : 31)	θ value	1.32909e-35 (rank : 24)
Query Neighborhood Hits	58	Target Neighborhood Hits	45	Shared Neighborhood Hits	33
SwissProt Accessions	P48058	Gene names	GRIA4, GLUR4
Domain Architecture
Description	Glutamate receptor 4 precursor (GluR-4) (GluR4) (GluR-D) (Glutamate receptor ionotropic, AMPA 4) (AMPA-selective glutamate receptor 4).

GRIA4_MOUSE
NC score	0.854638 (rank : 32)	θ value	7.29293e-34 (rank : 30)
Query Neighborhood Hits	58	Target Neighborhood Hits	44	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Z2W8	Gene names	Gria4, Glur4
Domain Architecture
Description	Glutamate receptor 4 precursor (GluR-4) (GluR4) (GluR-D) (Glutamate receptor ionotropic, AMPA 4) (AMPA-selective glutamate receptor 4).

GRIK1_MOUSE
NC score	0.849246 (rank : 33)	θ value	3.07116e-24 (rank : 33)
Query Neighborhood Hits	58	Target Neighborhood Hits	46	Shared Neighborhood Hits	35
SwissProt Accessions	Q60934	Gene names	Grik1, Glur5
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 1 precursor (Glutamate receptor 5) (GluR-5) (GluR5).

ERB1_HUMAN
NC score	0.087530 (rank : 34)	θ value	θ > 10 (rank : 59)
Query Neighborhood Hits	58	Target Neighborhood Hits	23	Shared Neighborhood Hits	8
SwissProt Accessions	P60509	Gene names
Domain Architecture	No domain graphic available
Description	HERV-R(b)_3p24.3 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (HERV-R(b) Env protein) [Includes: Surface protein domain (SU); Transmembrane protein domain (TM)].

GABR1_HUMAN
NC score	0.051155 (rank : 35)	θ value	θ > 10 (rank : 60)
Query Neighborhood Hits	58	Target Neighborhood Hits	142	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UBS5, O95375, O95468, O95975, O96022, Q86W60, Q9UQQ0	Gene names	GABBR1, GPRC3A
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 1 precursor (GABA-B receptor 1) (GABA-B-R1) (Gb1).

GABR1_MOUSE
NC score	0.051042 (rank : 36)	θ value	θ > 10 (rank : 61)
Query Neighborhood Hits	58	Target Neighborhood Hits	139	Shared Neighborhood Hits	18
SwissProt Accessions	Q9WV18, Q9WU48, Q9WV15, Q9WV16, Q9WV17	Gene names	Gabbr1
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 1 precursor (GABA-B receptor 1) (GABA-B-R1) (Gb1).

MGR1_MOUSE
NC score	0.039432 (rank : 37)	θ value	0.365318 (rank : 35)
Query Neighborhood Hits	58	Target Neighborhood Hits	90	Shared Neighborhood Hits	13
SwissProt Accessions	P97772, Q6AXG4, Q9EPV6	Gene names	Grm1, Gprc1a, Mglur1
Domain Architecture
Description	Metabotropic glutamate receptor 1 precursor (mGluR1).

MGR1_HUMAN
NC score	0.039417 (rank : 38)	θ value	0.365318 (rank : 34)
Query Neighborhood Hits	58	Target Neighborhood Hits	85	Shared Neighborhood Hits	13
SwissProt Accessions	Q13255, Q13256, Q14757, Q14758, Q5VTF7, Q5VTF8, Q9NU10, Q9UGS9, Q9UGT0	Gene names	GRM1, GPRC1A, MGLUR1
Domain Architecture
Description	Metabotropic glutamate receptor 1 precursor (mGluR1).

MGR4_HUMAN
NC score	0.026669 (rank : 39)	θ value	3.0926 (rank : 43)
Query Neighborhood Hits	58	Target Neighborhood Hits	63	Shared Neighborhood Hits	10
SwissProt Accessions	Q14833, Q5SZ84	Gene names	GRM4, GPRC1D, MGLUR4
Domain Architecture
Description	Metabotropic glutamate receptor 4 precursor (mGluR4).

IF_HUMAN
NC score	0.016316 (rank : 40)	θ value	1.38821 (rank : 39)
Query Neighborhood Hits	58	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	P27352	Gene names	GIF, IFMH
Domain Architecture
Description	Gastric intrinsic factor precursor (Intrinsic factor) (IF) (INF).

PSL1_HUMAN
NC score	0.016312 (rank : 41)	θ value	8.99809 (rank : 58)
Query Neighborhood Hits	58	Target Neighborhood Hits	650	Shared Neighborhood Hits	8
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

DIAP3_HUMAN
NC score	0.015305 (rank : 42)	θ value	3.0926 (rank : 42)
Query Neighborhood Hits	58	Target Neighborhood Hits	209	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NSV4, Q5T2S7, Q5XKF6, Q6MZF0, Q6NUP0, Q86VS4, Q8NAV4	Gene names	DIAPH3, DIAP3
Domain Architecture	No domain graphic available
Description	Protein diaphanous homolog 3 (Diaphanous-related formin-3) (DRF3).

CTL3_MOUSE
NC score	0.010856 (rank : 43)	θ value	3.0926 (rank : 41)
Query Neighborhood Hits	58	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	Q921V7	Gene names	Slc44a3, Ctl3
Domain Architecture	No domain graphic available
Description	Choline transporter-like protein 3 (Solute carrier family 44 member 3).

DIDO1_HUMAN
NC score	0.010776 (rank : 44)	θ value	1.38821 (rank : 38)
Query Neighborhood Hits	58	Target Neighborhood Hits	960	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

CTL3_HUMAN
NC score	0.009626 (rank : 45)	θ value	5.27518 (rank : 46)
Query Neighborhood Hits	58	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N4M1, Q6UWT1, Q9BWY7	Gene names	SLC44A3, CTL3
Domain Architecture	No domain graphic available
Description	Choline transporter-like protein 3 (Solute carrier family 44 member 3).

GO45_HUMAN
NC score	0.008537 (rank : 46)	θ value	5.27518 (rank : 48)
Query Neighborhood Hits	58	Target Neighborhood Hits	189	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H2G9, O15298, Q5T531, Q9GZX4	Gene names	BLZF1, JEM1
Domain Architecture	No domain graphic available
Description	Golgin 45 (Basic leucine zipper nuclear factor 1) (JEM-1) (p45 basic leucine-zipper nuclear factor).

ACD_HUMAN
NC score	0.008140 (rank : 47)	θ value	6.88961 (rank : 52)
Query Neighborhood Hits	58	Target Neighborhood Hits	143	Shared Neighborhood Hits	2
SwissProt Accessions	Q96AP0, Q562H5, Q9H8F9	Gene names	ACD, PIP1, PTOP
Domain Architecture	No domain graphic available
Description	Adrenocortical dysplasia protein homolog (POT1 and TIN2-interacting protein).

RIN1_HUMAN
NC score	0.007438 (rank : 48)	θ value	5.27518 (rank : 49)
Query Neighborhood Hits	58	Target Neighborhood Hits	52	Shared Neighborhood Hits	2
SwissProt Accessions	Q13671, O15010, Q00427, Q96CC8	Gene names	RIN1
Domain Architecture
Description	Ras and Rab interactor 1 (Ras interaction/interference protein 1) (Ras inhibitor JC99).

TRAF3_HUMAN
NC score	0.005786 (rank : 49)	θ value	5.27518 (rank : 50)
Query Neighborhood Hits	58	Target Neighborhood Hits	463	Shared Neighborhood Hits	6
SwissProt Accessions	Q13114, Q12990, Q13076, Q13947, Q6AZX1, Q9UNL1	Gene names	TRAF3, CAP1, CRAF1
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein) (LAP1) (CAP-1).

TRAF3_MOUSE
NC score	0.005747 (rank : 50)	θ value	5.27518 (rank : 51)
Query Neighborhood Hits	58	Target Neighborhood Hits	476	Shared Neighborhood Hits	6
SwissProt Accessions	Q60803, Q62380	Gene names	Traf3, Craf1, Trafamn
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (TRAFAMN).

TLR8_MOUSE
NC score	0.005341 (rank : 51)	θ value	0.47712 (rank : 36)
Query Neighborhood Hits	58	Target Neighborhood Hits	297	Shared Neighborhood Hits	2
SwissProt Accessions	P58682, Q91XI7	Gene names	Tlr8
Domain Architecture
Description	Toll-like receptor 8 precursor.

FZD8_HUMAN
NC score	0.003625 (rank : 52)	θ value	5.27518 (rank : 47)
Query Neighborhood Hits	58	Target Neighborhood Hits	88	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H461	Gene names	FZD8
Domain Architecture
Description	Frizzled-8 precursor (Fz-8) (hFz8).

ARSD_HUMAN
NC score	0.003226 (rank : 53)	θ value	8.99809 (rank : 54)
Query Neighborhood Hits	58	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	P51689, Q9UHJ8	Gene names	ARSD
Domain Architecture
Description	Arylsulfatase D precursor (EC 3.1.6.-) (ASD).

FZD8_MOUSE
NC score	0.003024 (rank : 54)	θ value	8.99809 (rank : 55)
Query Neighborhood Hits	58	Target Neighborhood Hits	89	Shared Neighborhood Hits	4
SwissProt Accessions	Q61091	Gene names	Fzd8
Domain Architecture
Description	Frizzled-8 precursor (Fz-8) (mFz8).

JIP3_HUMAN
NC score	0.002593 (rank : 55)	θ value	8.99809 (rank : 57)
Query Neighborhood Hits	58	Target Neighborhood Hits	1039	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

HOOK1_HUMAN
NC score	0.001455 (rank : 56)	θ value	4.03905 (rank : 44)
Query Neighborhood Hits	58	Target Neighborhood Hits	942	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UJC3, O60561, Q5TG44	Gene names	HOOK1
Domain Architecture
Description	Hook homolog 1 (h-hook1) (hHK1).

CCD46_HUMAN
NC score	0.001214 (rank : 57)	θ value	0.813845 (rank : 37)
Query Neighborhood Hits	58	Target Neighborhood Hits	1430	Shared Neighborhood Hits	7
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

EEA1_HUMAN
NC score	-0.000907 (rank : 58)	θ value	2.36792 (rank : 40)
Query Neighborhood Hits	58	Target Neighborhood Hits	1796	Shared Neighborhood Hits	11
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

TPR_HUMAN
NC score	-0.001577 (rank : 59)	θ value	4.03905 (rank : 45)
Query Neighborhood Hits	58	Target Neighborhood Hits	1921	Shared Neighborhood Hits	10
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

GOGB1_HUMAN
NC score	-0.002962 (rank : 60)	θ value	8.99809 (rank : 56)
Query Neighborhood Hits	58	Target Neighborhood Hits	2297	Shared Neighborhood Hits	12
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

ALK_MOUSE
NC score	-0.003728 (rank : 61)	θ value	8.99809 (rank : 53)
Query Neighborhood Hits	58	Target Neighborhood Hits	811	Shared Neighborhood Hits	2
SwissProt Accessions	P97793	Gene names	Alk
Domain Architecture
Description	ALK tyrosine kinase receptor precursor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD246 antigen).