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Network neighborhood for query Sequence : MGR1_MOUSE

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MGR1_MOUSE
SwissProt Accessions	P97772, Q6AXG4, Q9EPV6	Gene names	Grm1, Gprc1a, Mglur1
Domain Architecture
Description	Metabotropic glutamate receptor 1 precursor (mGluR1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

MGR1_HUMAN
θ value	0 (rank : 1)	NC score	0.997411 (rank : 2)
Query Neighborhood Hits	90	Target Neighborhood Hits	85	Shared Neighborhood Hits	57
SwissProt Accessions	Q13255, Q13256, Q14757, Q14758, Q5VTF7, Q5VTF8, Q9NU10, Q9UGS9, Q9UGT0	Gene names	GRM1, GPRC1A, MGLUR1
Domain Architecture
Description	Metabotropic glutamate receptor 1 precursor (mGluR1).

MGR1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	90	Target Neighborhood Hits	90	Shared Neighborhood Hits	90
SwissProt Accessions	P97772, Q6AXG4, Q9EPV6	Gene names	Grm1, Gprc1a, Mglur1
Domain Architecture
Description	Metabotropic glutamate receptor 1 precursor (mGluR1).

MGR2_HUMAN
θ value	0 (rank : 3)	NC score	0.979508 (rank : 4)
Query Neighborhood Hits	90	Target Neighborhood Hits	56	Shared Neighborhood Hits	40
SwissProt Accessions	Q14416, Q52MC6, Q9H3N6	Gene names	GRM2, GPRC1B, MGLUR2
Domain Architecture
Description	Metabotropic glutamate receptor 2 precursor (mGluR2).

MGR5_HUMAN
θ value	0 (rank : 4)	NC score	0.992949 (rank : 3)
Query Neighborhood Hits	90	Target Neighborhood Hits	72	Shared Neighborhood Hits	45
SwissProt Accessions	P41594	Gene names	GRM5, GPRC1E, MGLUR5
Domain Architecture
Description	Metabotropic glutamate receptor 5 precursor (mGluR5).

MGR3_HUMAN
θ value	8.53067e-184 (rank : 5)	NC score	0.976398 (rank : 5)
Query Neighborhood Hits	90	Target Neighborhood Hits	58	Shared Neighborhood Hits	40
SwissProt Accessions	Q14832, Q75MV4, Q75N17, Q86YG6, Q8TBH9	Gene names	GRM3, GPRC1C, MGLUR3
Domain Architecture
Description	Metabotropic glutamate receptor 3 precursor (mGluR3).

MGR3_MOUSE
θ value	1.11414e-183 (rank : 6)	NC score	0.976015 (rank : 6)
Query Neighborhood Hits	90	Target Neighborhood Hits	54	Shared Neighborhood Hits	39
SwissProt Accessions	Q9QYS2	Gene names	Grm3, Gprc1c, Mglur3
Domain Architecture
Description	Metabotropic glutamate receptor 3 precursor (mGluR3).

MGR4_HUMAN
θ value	4.1007e-178 (rank : 7)	NC score	0.975513 (rank : 7)
Query Neighborhood Hits	90	Target Neighborhood Hits	63	Shared Neighborhood Hits	42
SwissProt Accessions	Q14833, Q5SZ84	Gene names	GRM4, GPRC1D, MGLUR4
Domain Architecture
Description	Metabotropic glutamate receptor 4 precursor (mGluR4).

MGR8_HUMAN
θ value	5.01279e-176 (rank : 8)	NC score	0.973701 (rank : 10)
Query Neighborhood Hits	90	Target Neighborhood Hits	49	Shared Neighborhood Hits	36
SwissProt Accessions	O00222, O15493, O95945, O95946, Q3MIV9, Q52M02, Q6J165	Gene names	GRM8, GPRC1H, MGLUR8
Domain Architecture
Description	Metabotropic glutamate receptor 8 precursor (mGluR8).

MGR7_MOUSE
θ value	1.11673e-175 (rank : 9)	NC score	0.972045 (rank : 13)
Query Neighborhood Hits	90	Target Neighborhood Hits	53	Shared Neighborhood Hits	34
SwissProt Accessions	Q68ED2	Gene names	Grm7, Gprc1g, Mglur7
Domain Architecture	No domain graphic available
Description	Metabotropic glutamate receptor 7 precursor (mGluR7).

MGR8_MOUSE
θ value	1.11673e-175 (rank : 10)	NC score	0.973737 (rank : 9)
Query Neighborhood Hits	90	Target Neighborhood Hits	44	Shared Neighborhood Hits	36
SwissProt Accessions	P47743, Q6B964	Gene names	Grm8, Gprc1h, Mglur8
Domain Architecture
Description	Metabotropic glutamate receptor 8 precursor (mGluR8).

MGR7_HUMAN
θ value	1.4585e-175 (rank : 11)	NC score	0.972153 (rank : 12)
Query Neighborhood Hits	90	Target Neighborhood Hits	52	Shared Neighborhood Hits	34
SwissProt Accessions	Q14831, Q8NFS2, Q8NFS3, Q8NFS4	Gene names	GRM7, GPRC1G, MGLUR7
Domain Architecture
Description	Metabotropic glutamate receptor 7 precursor (mGluR7).

MGR6_MOUSE
θ value	6.77497e-173 (rank : 12)	NC score	0.972546 (rank : 11)
Query Neighborhood Hits	90	Target Neighborhood Hits	56	Shared Neighborhood Hits	35
SwissProt Accessions	Q5NCH9	Gene names	Grm6, Gprc1f, Mglur6
Domain Architecture	No domain graphic available
Description	Metabotropic glutamate receptor 6 precursor (mGluR6).

MGR6_HUMAN
θ value	5.73535e-172 (rank : 13)	NC score	0.973800 (rank : 8)
Query Neighborhood Hits	90	Target Neighborhood Hits	58	Shared Neighborhood Hits	37
SwissProt Accessions	O15303	Gene names	GRM6, GPRC1F, MGLUR6
Domain Architecture
Description	Metabotropic glutamate receptor 6 precursor (mGluR6).

CASR_HUMAN
θ value	9.34977e-98 (rank : 14)	NC score	0.943547 (rank : 14)
Query Neighborhood Hits	90	Target Neighborhood Hits	71	Shared Neighborhood Hits	41
SwissProt Accessions	P41180, Q13912, Q16108, Q16109, Q16110, Q16379, Q4PJ19	Gene names	CASR, GPRC2A, PCAR1
Domain Architecture
Description	Extracellular calcium-sensing receptor precursor (CaSR) (Parathyroid Cell calcium-sensing receptor).

CASR_MOUSE
θ value	3.55291e-97 (rank : 15)	NC score	0.943510 (rank : 15)
Query Neighborhood Hits	90	Target Neighborhood Hits	72	Shared Neighborhood Hits	41
SwissProt Accessions	Q9QY96, O08968, O88519, Q9QY95, Q9QZU8, Q9R1D6, Q9R1Y2	Gene names	Casr, Gprc2a
Domain Architecture
Description	Extracellular calcium-sensing receptor precursor (CaSR) (Parathyroid Cell calcium-sensing receptor).

V2RX_MOUSE
θ value	2.47765e-74 (rank : 16)	NC score	0.933672 (rank : 16)
Query Neighborhood Hits	90	Target Neighborhood Hits	45	Shared Neighborhood Hits	30
SwissProt Accessions	O70410	Gene names
Domain Architecture	No domain graphic available
Description	Vomeronasal type-2 receptor X precursor (Putative pheromone receptor V2RX).

TS1R1_MOUSE
θ value	1.2325e-65 (rank : 17)	NC score	0.906602 (rank : 21)
Query Neighborhood Hits	90	Target Neighborhood Hits	57	Shared Neighborhood Hits	37
SwissProt Accessions	Q99PG6, Q6NS58, Q923J9, Q925I5, Q99PG5	Gene names	Tas1r1, Gpr70, T1r1, Tr1
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 1 precursor (G-protein coupled receptor 70).

TS1R1_HUMAN
θ value	2.32439e-64 (rank : 18)	NC score	0.906061 (rank : 22)
Query Neighborhood Hits	90	Target Neighborhood Hits	72	Shared Neighborhood Hits	33
SwissProt Accessions	Q7RTX1, Q8NGZ7, Q8TDJ7, Q8TDJ8, Q8TDJ9, Q8TDK0	Gene names	TAS1R1, GPR70, T1R1, TR1
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 1 precursor (G-protein coupled receptor 70) (Gm148).

GPC6A_HUMAN
θ value	4.38363e-63 (rank : 19)	NC score	0.915073 (rank : 18)
Query Neighborhood Hits	90	Target Neighborhood Hits	53	Shared Neighborhood Hits	34
SwissProt Accessions	Q5T6X5, Q6JK43, Q6JK44, Q8NGU8, Q8NHZ9, Q8TDT6	Gene names	GPRC6A, GPCR33
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor family C group 6 member A precursor (hGPRC6A) (G-protein coupled receptor 33) (hGPCR33).

GPC6A_MOUSE
θ value	2.84138e-62 (rank : 20)	NC score	0.913057 (rank : 19)
Query Neighborhood Hits	90	Target Neighborhood Hits	57	Shared Neighborhood Hits	34
SwissProt Accessions	Q8K4Z6, Q5DK51, Q5DK52	Gene names	Gprc6a
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor family C group 6 member A precursor.

TS1R2_HUMAN
θ value	7.01481e-53 (rank : 21)	NC score	0.904562 (rank : 23)
Query Neighborhood Hits	90	Target Neighborhood Hits	48	Shared Neighborhood Hits	38
SwissProt Accessions	Q8TE23, Q5TZ19	Gene names	TAS1R2, GPR71, T1R2, TR2
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 2 precursor (G-protein coupled receptor 71) (Sweet taste receptor T1R2).

TS1R2_MOUSE
θ value	5.02714e-51 (rank : 22)	NC score	0.908324 (rank : 20)
Query Neighborhood Hits	90	Target Neighborhood Hits	69	Shared Neighborhood Hits	41
SwissProt Accessions	Q925I4, Q923J8	Gene names	Tas1r2, Gpr71, T1r2, Tr2
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 2 precursor (G-protein coupled receptor 71) (Sweet taste receptor T1R2).

TS1R3_MOUSE
θ value	8.57503e-51 (rank : 23)	NC score	0.893618 (rank : 24)
Query Neighborhood Hits	90	Target Neighborhood Hits	49	Shared Neighborhood Hits	32
SwissProt Accessions	Q925D8, Q91VA4, Q923K0, Q925A4, Q925D9	Gene names	Tas1r3, Sac, T1r3, Tr3
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 3 precursor (Sweet taste receptor T1R3) (Saccharin preference protein).

V2R1B_MOUSE
θ value	1.61718e-49 (rank : 24)	NC score	0.920796 (rank : 17)
Query Neighborhood Hits	90	Target Neighborhood Hits	39	Shared Neighborhood Hits	26
SwissProt Accessions	Q6TAC4, O70409	Gene names	V2r1b
Domain Architecture	No domain graphic available
Description	Vomeronasal type-2 receptor 1b precursor (Putative pheromone receptor V2R1b).

TS1R3_HUMAN
θ value	4.86918e-46 (rank : 25)	NC score	0.888386 (rank : 25)
Query Neighborhood Hits	90	Target Neighborhood Hits	46	Shared Neighborhood Hits	30
SwissProt Accessions	Q7RTX0, Q5TA49, Q8NGW9	Gene names	TAS1R3, T1R3, TR3
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 3 precursor (Sweet taste receptor T1R3).

GABR2_HUMAN
θ value	1.29631e-06 (rank : 26)	NC score	0.531294 (rank : 26)
Query Neighborhood Hits	90	Target Neighborhood Hits	101	Shared Neighborhood Hits	40
SwissProt Accessions	O75899, O75974, O75975, Q5VXZ2, Q8WX04, Q9P1R2, Q9UNR1, Q9UNS9	Gene names	GABBR2, GPR51, GPRC3B
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 2 precursor (GABA-B receptor 2) (GABA-B-R2) (Gb2) (GABABR2) (G-protein coupled receptor 51) (HG20).

ANPRC_MOUSE
θ value	2.21117e-06 (rank : 27)	NC score	0.157327 (rank : 38)
Query Neighborhood Hits	90	Target Neighborhood Hits	27	Shared Neighborhood Hits	20
SwissProt Accessions	P70180, P97804, Q9R025, Q9R027, Q9R028	Gene names	Npr3
Domain Architecture
Description	Atrial natriuretic peptide clearance receptor precursor (ANP-C) (ANPRC) (NPR-C) (Atrial natriuretic peptide C-type receptor) (EF-2).

GP158_HUMAN
θ value	1.09739e-05 (rank : 28)	NC score	0.246178 (rank : 31)
Query Neighborhood Hits	90	Target Neighborhood Hits	221	Shared Neighborhood Hits	24
SwissProt Accessions	Q5T848, Q6QR81, Q9ULT3	Gene names	GPR158, KIAA1136
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 158 precursor.

GP179_HUMAN
θ value	1.09739e-05 (rank : 29)	NC score	0.198527 (rank : 35)
Query Neighborhood Hits	90	Target Neighborhood Hits	372	Shared Neighborhood Hits	21
SwissProt Accessions	Q6PRD1	Gene names	GPR179, GPR158L1
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 179 precursor (Probable G-protein coupled receptor 158-like 1).

GABR1_HUMAN
θ value	1.43324e-05 (rank : 30)	NC score	0.408627 (rank : 28)
Query Neighborhood Hits	90	Target Neighborhood Hits	142	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UBS5, O95375, O95468, O95975, O96022, Q86W60, Q9UQQ0	Gene names	GABBR1, GPRC3A
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 1 precursor (GABA-B receptor 1) (GABA-B-R1) (Gb1).

GABR1_MOUSE
θ value	1.43324e-05 (rank : 31)	NC score	0.408653 (rank : 27)
Query Neighborhood Hits	90	Target Neighborhood Hits	139	Shared Neighborhood Hits	33
SwissProt Accessions	Q9WV18, Q9WU48, Q9WV15, Q9WV16, Q9WV17	Gene names	Gabbr1
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 1 precursor (GABA-B receptor 1) (GABA-B-R1) (Gb1).

ANPRC_HUMAN
θ value	0.000270298 (rank : 32)	NC score	0.136380 (rank : 39)
Query Neighborhood Hits	90	Target Neighborhood Hits	27	Shared Neighborhood Hits	19
SwissProt Accessions	P17342	Gene names	NPR3, ANPRC
Domain Architecture
Description	Atrial natriuretic peptide clearance receptor precursor (ANP-C) (ANPRC) (NPR-C) (Atrial natriuretic peptide C-type receptor).

GPC5B_HUMAN
θ value	0.00035302 (rank : 33)	NC score	0.294890 (rank : 30)
Query Neighborhood Hits	90	Target Neighborhood Hits	28	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NZH0, O75205, Q8NBZ8	Gene names	GPRC5B, RAIG2
Domain Architecture
Description	G-protein coupled receptor family C group 5 member B precursor (Retinoic acid-induced gene 2 protein) (RAIG-2) (A-69G12.1).

GP158_MOUSE
θ value	0.000786445 (rank : 34)	NC score	0.225011 (rank : 32)
Query Neighborhood Hits	90	Target Neighborhood Hits	82	Shared Neighborhood Hits	18
SwissProt Accessions	Q8C419, Q8CHB0	Gene names	Gpr158, Kiaa1136
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 158 precursor.

GPC5B_MOUSE
θ value	0.000786445 (rank : 35)	NC score	0.320249 (rank : 29)
Query Neighborhood Hits	90	Target Neighborhood Hits	33	Shared Neighborhood Hits	23
SwissProt Accessions	Q923Z0, Q8CCV3	Gene names	Gprc5b, Raig2
Domain Architecture
Description	G-protein coupled receptor family C group 5 member B precursor (Retinoic acid-induced gene 2 protein) (RAIG-2).

GPC5C_MOUSE
θ value	0.00134147 (rank : 36)	NC score	0.181898 (rank : 36)
Query Neighborhood Hits	90	Target Neighborhood Hits	25	Shared Neighborhood Hits	17
SwissProt Accessions	Q8K3J9, Q8K0H0	Gene names	Gprc5c, Raig3
Domain Architecture
Description	G-protein coupled receptor family C group 5 member C precursor (Retinoic acid-induced gene 3 protein) (RAIG-3).

GRIK1_HUMAN
θ value	0.00134147 (rank : 37)	NC score	0.068709 (rank : 48)
Query Neighborhood Hits	90	Target Neighborhood Hits	48	Shared Neighborhood Hits	20
SwissProt Accessions	P39086, Q13001, Q86SU9	Gene names	GRIK1, GLUR5
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 1 precursor (Glutamate receptor 5) (GluR-5) (GluR5) (Excitatory amino acid receptor 3) (EAA3).

GUC2G_MOUSE
θ value	0.00175202 (rank : 38)	NC score	0.057305 (rank : 49)
Query Neighborhood Hits	90	Target Neighborhood Hits	644	Shared Neighborhood Hits	22
SwissProt Accessions	Q6TL19, Q8BWU7	Gene names	Gucy2g
Domain Architecture	No domain graphic available
Description	Guanylate cyclase 2G precursor (EC 4.6.1.2) (Guanylyl cyclase receptor G) (mGC-G).

GRIK1_MOUSE
θ value	0.00228821 (rank : 39)	NC score	0.068897 (rank : 47)
Query Neighborhood Hits	90	Target Neighborhood Hits	46	Shared Neighborhood Hits	20
SwissProt Accessions	Q60934	Gene names	Grik1, Glur5
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 1 precursor (Glutamate receptor 5) (GluR-5) (GluR5).

NMDZ1_MOUSE
θ value	0.0113563 (rank : 40)	NC score	0.201881 (rank : 33)
Query Neighborhood Hits	90	Target Neighborhood Hits	76	Shared Neighborhood Hits	38
SwissProt Accessions	P35438, Q8CFS4	Gene names	Grin1, Glurz1
Domain Architecture
Description	Glutamate [NMDA] receptor subunit zeta 1 precursor (N-methyl-D- aspartate receptor subunit NR1).

BCAR1_MOUSE
θ value	0.0252991 (rank : 41)	NC score	0.041177 (rank : 51)
Query Neighborhood Hits	90	Target Neighborhood Hits	438	Shared Neighborhood Hits	11
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

GRIK2_HUMAN
θ value	0.0431538 (rank : 42)	NC score	0.069019 (rank : 46)
Query Neighborhood Hits	90	Target Neighborhood Hits	50	Shared Neighborhood Hits	21
SwissProt Accessions	Q13002	Gene names	GRIK2, GLUR6
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 2 precursor (Glutamate receptor 6) (GluR-6) (GluR6) (Excitatory amino acid receptor 4) (EAA4).

NMDZ1_HUMAN
θ value	0.0431538 (rank : 43)	NC score	0.198650 (rank : 34)
Query Neighborhood Hits	90	Target Neighborhood Hits	77	Shared Neighborhood Hits	38
SwissProt Accessions	Q05586, P35437, Q12867, Q12868	Gene names	GRIN1, NMDAR1
Domain Architecture
Description	Glutamate [NMDA] receptor subunit zeta 1 precursor (N-methyl-D- aspartate receptor subunit NR1).

NOTC2_MOUSE
θ value	0.0563607 (rank : 44)	NC score	0.005021 (rank : 79)
Query Neighborhood Hits	90	Target Neighborhood Hits	1069	Shared Neighborhood Hits	12
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

CSKI2_MOUSE
θ value	0.0736092 (rank : 45)	NC score	0.007813 (rank : 75)
Query Neighborhood Hits	90	Target Neighborhood Hits	812	Shared Neighborhood Hits	16
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

PRD14_HUMAN
θ value	0.0961366 (rank : 46)	NC score	-0.000869 (rank : 92)
Query Neighborhood Hits	90	Target Neighborhood Hits	757	Shared Neighborhood Hits	5
SwissProt Accessions	Q9GZV8, Q86UX9	Gene names	PRDM14
Domain Architecture
Description	PR domain zinc finger protein 14 (PR domain-containing protein 14).

GR65_MOUSE
θ value	0.163984 (rank : 47)	NC score	0.021052 (rank : 58)
Query Neighborhood Hits	90	Target Neighborhood Hits	54	Shared Neighborhood Hits	4
SwissProt Accessions	Q91X51, Q9D3L9	Gene names	Gorasp1
Domain Architecture	No domain graphic available
Description	Golgi reassembly-stacking protein 1 (Golgi reassembly-stacking protein of 65 kDa) (GRASP65) (Golgi peripheral membrane protein p65).

GPC5C_HUMAN
θ value	0.21417 (rank : 48)	NC score	0.157541 (rank : 37)
Query Neighborhood Hits	90	Target Neighborhood Hits	26	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NQ84, Q9NZG5	Gene names	GPRC5C, RAIG3
Domain Architecture
Description	G-protein coupled receptor family C group 5 member C precursor (Retinoic acid-induced gene 3 protein) (RAIG-3).

LZTR1_MOUSE
θ value	0.21417 (rank : 49)	NC score	0.016567 (rank : 59)
Query Neighborhood Hits	90	Target Neighborhood Hits	200	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CQ33	Gene names	Lztr1, Tcfl2
Domain Architecture
Description	Leucine-zipper-like transcriptional regulator 1 (LZTR-1).

RGS3_MOUSE
θ value	0.279714 (rank : 50)	NC score	0.010183 (rank : 72)
Query Neighborhood Hits	90	Target Neighborhood Hits	1621	Shared Neighborhood Hits	23
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

BCAR1_HUMAN
θ value	0.365318 (rank : 51)	NC score	0.032286 (rank : 56)
Query Neighborhood Hits	90	Target Neighborhood Hits	554	Shared Neighborhood Hits	12
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

MAP1A_HUMAN
θ value	0.365318 (rank : 52)	NC score	0.010565 (rank : 71)
Query Neighborhood Hits	90	Target Neighborhood Hits	1626	Shared Neighborhood Hits	15
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

NMD3A_HUMAN
θ value	0.365318 (rank : 53)	NC score	0.039432 (rank : 52)
Query Neighborhood Hits	90	Target Neighborhood Hits	58	Shared Neighborhood Hits	13
SwissProt Accessions	Q8TCU5, Q8TF29, Q8WXI6	Gene names	GRIN3A, KIAA1973
Domain Architecture	No domain graphic available
Description	Glutamate [NMDA] receptor subunit 3A precursor (N-methyl-D-aspartate receptor subtype NR3A) (NMDAR-L).

HSF1_MOUSE
θ value	0.47712 (rank : 54)	NC score	0.013453 (rank : 66)
Query Neighborhood Hits	90	Target Neighborhood Hits	267	Shared Neighborhood Hits	6
SwissProt Accessions	P38532, O70462	Gene names	Hsf1
Domain Architecture
Description	Heat shock factor protein 1 (HSF 1) (Heat shock transcription factor 1) (HSTF 1).

NCOA6_MOUSE
θ value	0.47712 (rank : 55)	NC score	0.016466 (rank : 60)
Query Neighborhood Hits	90	Target Neighborhood Hits	1076	Shared Neighborhood Hits	24
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

LZTR1_HUMAN
θ value	0.62314 (rank : 56)	NC score	0.015106 (rank : 62)
Query Neighborhood Hits	90	Target Neighborhood Hits	196	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N653, Q14776	Gene names	LZTR1, TCFL2
Domain Architecture
Description	Leucine-zipper-like transcriptional regulator 1 (LZTR-1).

NCOA6_HUMAN
θ value	0.62314 (rank : 57)	NC score	0.014276 (rank : 64)
Query Neighborhood Hits	90	Target Neighborhood Hits	1202	Shared Neighborhood Hits	21
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

ZN516_MOUSE
θ value	1.06291 (rank : 58)	NC score	-0.001269 (rank : 93)
Query Neighborhood Hits	90	Target Neighborhood Hits	1197	Shared Neighborhood Hits	13
SwissProt Accessions	Q7TSH3	Gene names	Znf516, Kiaa0222, Zfp516
Domain Architecture
Description	Zinc finger protein 516.

ECM1_MOUSE
θ value	1.38821 (rank : 59)	NC score	0.014934 (rank : 63)
Query Neighborhood Hits	90	Target Neighborhood Hits	105	Shared Neighborhood Hits	5
SwissProt Accessions	Q61508	Gene names	Ecm1
Domain Architecture
Description	Extracellular matrix protein 1 precursor (Secretory component p85).

GLIS3_MOUSE
θ value	1.38821 (rank : 60)	NC score	-0.001723 (rank : 94)
Query Neighborhood Hits	90	Target Neighborhood Hits	861	Shared Neighborhood Hits	7
SwissProt Accessions	Q6XP49, Q8BI60	Gene names	Glis3
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLIS3 (GLI-similar 3).

NFAC2_HUMAN
θ value	1.38821 (rank : 61)	NC score	0.013645 (rank : 65)
Query Neighborhood Hits	90	Target Neighborhood Hits	101	Shared Neighborhood Hits	6
SwissProt Accessions	Q13469, Q13468, Q5TFW7, Q5TFW8, Q9NPX6, Q9NQH3, Q9UJR2	Gene names	NFATC2, NFAT1, NFATP
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 2 (T cell transcription factor NFAT1) (NFAT pre-existing subunit) (NF-ATp).

NFAC2_MOUSE
θ value	1.38821 (rank : 62)	NC score	0.013178 (rank : 67)
Query Neighborhood Hits	90	Target Neighborhood Hits	98	Shared Neighborhood Hits	4
SwissProt Accessions	Q60591, Q60984, Q60985	Gene names	Nfatc2, Nfat1, Nfatp
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 2 (T cell transcription factor NFAT1) (NFAT pre-existing subunit) (NF-ATp).

LTBP2_MOUSE
θ value	1.81305 (rank : 63)	NC score	0.011422 (rank : 70)
Query Neighborhood Hits	90	Target Neighborhood Hits	617	Shared Neighborhood Hits	15
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

NPAS4_MOUSE
θ value	1.81305 (rank : 64)	NC score	0.012736 (rank : 68)
Query Neighborhood Hits	90	Target Neighborhood Hits	245	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BGD7, Q3V3U3	Gene names	Npas4, Nxf
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF) (Limbic-enhanced PAS protein) (LE-PAS).

GRIK3_HUMAN
θ value	2.36792 (rank : 65)	NC score	0.043468 (rank : 50)
Query Neighborhood Hits	90	Target Neighborhood Hits	41	Shared Neighborhood Hits	17
SwissProt Accessions	Q13003, Q13004, Q16136	Gene names	GRIK3, GLUR7
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 3 precursor (Glutamate receptor 7) (GluR-7) (GluR7) (Excitatory amino acid receptor 5) (EAA5).

MKL1_MOUSE
θ value	2.36792 (rank : 66)	NC score	0.007885 (rank : 74)
Query Neighborhood Hits	90	Target Neighborhood Hits	667	Shared Neighborhood Hits	13
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

NMDE2_HUMAN
θ value	2.36792 (rank : 67)	NC score	0.034134 (rank : 54)
Query Neighborhood Hits	90	Target Neighborhood Hits	65	Shared Neighborhood Hits	14
SwissProt Accessions	Q13224, Q12919, Q13220, Q13225, Q9UM56	Gene names	GRIN2B
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 2 precursor (N-methyl D- aspartate receptor subtype 2B) (NR2B) (NMDAR2B) (N-methyl-D-aspartate receptor subunit 3) (NR3) (hNR3).

NMDE2_MOUSE
θ value	2.36792 (rank : 68)	NC score	0.034412 (rank : 53)
Query Neighborhood Hits	90	Target Neighborhood Hits	64	Shared Neighborhood Hits	16
SwissProt Accessions	Q01097, Q9DCB2	Gene names	Grin2b
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 2 precursor (N-methyl D- aspartate receptor subtype 2B) (NR2B) (NMDAR2B).

NPAS4_HUMAN
θ value	2.36792 (rank : 69)	NC score	0.011815 (rank : 69)
Query Neighborhood Hits	90	Target Neighborhood Hits	214	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IUM7, Q8N8S5, Q8N9Q9	Gene names	NPAS4, NXF
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF).

AFAD_HUMAN
θ value	3.0926 (rank : 70)	NC score	0.003739 (rank : 82)
Query Neighborhood Hits	90	Target Neighborhood Hits	689	Shared Neighborhood Hits	6
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

NMD3B_HUMAN
θ value	3.0926 (rank : 71)	NC score	0.032649 (rank : 55)
Query Neighborhood Hits	90	Target Neighborhood Hits	55	Shared Neighborhood Hits	12
SwissProt Accessions	O60391, Q5EAK7, Q7RTW9	Gene names	GRIN3B
Domain Architecture	No domain graphic available
Description	Glutamate [NMDA] receptor subunit 3B precursor (N-methyl-D-aspartate receptor subtype NR3B) (NR3B) (NMDAR3B).

AKAP3_MOUSE
θ value	4.03905 (rank : 72)	NC score	0.007698 (rank : 76)
Query Neighborhood Hits	90	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	O88987	Gene names	Akap3, Akap110
Domain Architecture
Description	A-kinase anchor protein 3 (Protein kinase A-anchoring protein 3) (PRKA3) (A-kinase anchor protein 110 kDa) (AKAP 110).

MAST2_HUMAN
θ value	4.03905 (rank : 73)	NC score	-0.003887 (rank : 96)
Query Neighborhood Hits	90	Target Neighborhood Hits	1189	Shared Neighborhood Hits	10
SwissProt Accessions	Q6P0Q8, O94899, Q5VT07, Q5VT08, Q7LGC4, Q8NDG1, Q96B94, Q9BYE8	Gene names	MAST2, KIAA0807, MAST205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

MLL3_MOUSE
θ value	4.03905 (rank : 74)	NC score	0.003801 (rank : 81)
Query Neighborhood Hits	90	Target Neighborhood Hits	1399	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

CRSP3_HUMAN
θ value	5.27518 (rank : 75)	NC score	0.015915 (rank : 61)
Query Neighborhood Hits	90	Target Neighborhood Hits	21	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ULK4, O95403, Q9H0J2, Q9NTT9, Q9NTU0, Q9Y5P7, Q9Y667	Gene names	CRSP3, ARC130, DRIP130, KIAA1216, SUR2
Domain Architecture	No domain graphic available
Description	CRSP complex subunit 3 (Cofactor required for Sp1 transcriptional activation subunit 3) (Transcriptional coactivator CRSP130) (Vitamin D3 receptor-interacting protein complex 130 kDa component) (DRIP130) (Activator-recruited cofactor 130 kDa component) (ARC130).

LTBP2_HUMAN
θ value	5.27518 (rank : 76)	NC score	0.008258 (rank : 73)
Query Neighborhood Hits	90	Target Neighborhood Hits	552	Shared Neighborhood Hits	12
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

NOTC2_HUMAN
θ value	5.27518 (rank : 77)	NC score	0.002902 (rank : 85)
Query Neighborhood Hits	90	Target Neighborhood Hits	1113	Shared Neighborhood Hits	12
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

PAX3_MOUSE
θ value	5.27518 (rank : 78)	NC score	-0.000563 (rank : 90)
Query Neighborhood Hits	90	Target Neighborhood Hits	478	Shared Neighborhood Hits	5
SwissProt Accessions	P24610, Q3UFQ9, Q8BRE7, Q9CXI6	Gene names	Pax3, Pax-3
Domain Architecture
Description	Paired box protein Pax-3.

ZIM10_HUMAN
θ value	5.27518 (rank : 79)	NC score	0.005102 (rank : 78)
Query Neighborhood Hits	90	Target Neighborhood Hits	577	Shared Neighborhood Hits	13
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

CCD21_HUMAN
θ value	6.88961 (rank : 80)	NC score	-0.002535 (rank : 95)
Query Neighborhood Hits	90	Target Neighborhood Hits	1228	Shared Neighborhood Hits	8
SwissProt Accessions	Q6P2H3, Q5VY68, Q5VY70, Q9H6Q1, Q9H828, Q9UF52	Gene names	CCDC21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

CE152_HUMAN
θ value	6.88961 (rank : 81)	NC score	-0.000650 (rank : 91)
Query Neighborhood Hits	90	Target Neighborhood Hits	976	Shared Neighborhood Hits	5
SwissProt Accessions	O94986, Q6NTA0	Gene names	CEP152, KIAA0912
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 152 kDa (Cep152 protein).

CO5_HUMAN
θ value	6.88961 (rank : 82)	NC score	0.006952 (rank : 77)
Query Neighborhood Hits	90	Target Neighborhood Hits	25	Shared Neighborhood Hits	4
SwissProt Accessions	P01031	Gene names	C5
Domain Architecture
Description	Complement C5 precursor [Contains: Complement C5 beta chain; Complement C5 alpha chain; C5a anaphylatoxin; Complement C5 alpha' chain].

COFA1_HUMAN
θ value	6.88961 (rank : 83)	NC score	0.003482 (rank : 83)
Query Neighborhood Hits	90	Target Neighborhood Hits	292	Shared Neighborhood Hits	9
SwissProt Accessions	P39059, Q5T6J4, Q9Y4W4	Gene names	COL15A1
Domain Architecture
Description	Collagen alpha-1(XV) chain precursor [Contains: Endostatin (Endostatin-XV) (Restin) (Related to endostatin)].

LR37A_HUMAN
θ value	6.88961 (rank : 84)	NC score	0.002820 (rank : 86)
Query Neighborhood Hits	90	Target Neighborhood Hits	720	Shared Neighborhood Hits	15
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

U258_HUMAN
θ value	6.88961 (rank : 85)	NC score	0.021118 (rank : 57)
Query Neighborhood Hits	90	Target Neighborhood Hits	6	Shared Neighborhood Hits	3
SwissProt Accessions	P59773	Gene names
Domain Architecture	No domain graphic available
Description	UPF0258 protein.

CD248_MOUSE
θ value	8.99809 (rank : 86)	NC score	0.002550 (rank : 87)
Query Neighborhood Hits	90	Target Neighborhood Hits	578	Shared Neighborhood Hits	13
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

GAK19_HUMAN
θ value	8.99809 (rank : 87)	NC score	0.003078 (rank : 84)
Query Neighborhood Hits	90	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	P62691	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_4p16.1 provirus ancestral Gag polyprotein (Gag polyprotein).

SSBP4_HUMAN
θ value	8.99809 (rank : 88)	NC score	0.001194 (rank : 89)
Query Neighborhood Hits	90	Target Neighborhood Hits	753	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

UB7I1_MOUSE
θ value	8.99809 (rank : 89)	NC score	0.004145 (rank : 80)
Query Neighborhood Hits	90	Target Neighborhood Hits	206	Shared Neighborhood Hits	6
SwissProt Accessions	P58283, Q3U493, Q3UE56, Q3UGM3, Q68FN0, Q6P1H8, Q6PWY5, Q8BN27, Q8C1U3	Gene names	Ubce7ip1, Triad3, Uip83, Zin
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase TRIAD3 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (UbcM4-interacting protein 83) (Triad domain- containing protein 3).

ZF106_MOUSE
θ value	8.99809 (rank : 90)	NC score	0.002025 (rank : 88)
Query Neighborhood Hits	90	Target Neighborhood Hits	472	Shared Neighborhood Hits	9
SwissProt Accessions	O88466, O55185, O88465, O88467, Q792M1, Q792P4, Q8CDZ8, Q8R3I4, Q9ESU3	Gene names	Zfp106, H3a, Sh3bp3, Sirm, Znf474
Domain Architecture	No domain graphic available
Description	Zinc finger protein 106 (Zfp-106) (Zinc finger protein 474) (H3a minor histocompatibility antigen) (Son of insulin receptor mutant).

GP156_HUMAN
θ value	θ > 10 (rank : 91)	NC score	0.098249 (rank : 43)
Query Neighborhood Hits	90	Target Neighborhood Hits	84	Shared Neighborhood Hits	17
SwissProt Accessions	Q8NFN8, Q86SN6	Gene names	GPR156, GABABL, PGR28
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 156 (GABAB-related G-protein coupled receptor) (G-protein coupled receptor PGR28).

GP156_MOUSE
θ value	θ > 10 (rank : 92)	NC score	0.118974 (rank : 40)
Query Neighborhood Hits	90	Target Neighborhood Hits	95	Shared Neighborhood Hits	16
SwissProt Accessions	Q6PCP7, Q8K452	Gene names	Gpr156, Gababl
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 156 (GABAB-related G-protein coupled receptor).

GPC5D_HUMAN
θ value	θ > 10 (rank : 93)	NC score	0.092498 (rank : 44)
Query Neighborhood Hits	90	Target Neighborhood Hits	21	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NZD1, Q3KNV3, Q7Z5J9, Q8TDS6	Gene names	GPRC5D
Domain Architecture
Description	G-protein coupled receptor family C group 5 member D.

GPC5D_MOUSE
θ value	θ > 10 (rank : 94)	NC score	0.117791 (rank : 41)
Query Neighborhood Hits	90	Target Neighborhood Hits	19	Shared Neighborhood Hits	12
SwissProt Accessions	Q9JIL6, Q8CJI0, Q8CJI1	Gene names	Gprc5d
Domain Architecture
Description	G-protein coupled receptor family C group 5 member D.

RAI3_HUMAN
θ value	θ > 10 (rank : 95)	NC score	0.082972 (rank : 45)
Query Neighborhood Hits	90	Target Neighborhood Hits	17	Shared Neighborhood Hits	9
SwissProt Accessions	Q8NFJ5, O95357	Gene names	GPRC5A, RAI3, RAIG1
Domain Architecture
Description	Retinoic acid-induced protein 3 (G-protein coupled receptor family C group 5 member A) (Retinoic acid-induced gene 1 protein) (RAIG-1) (Orphan G-protein coupling receptor PEIG-1).

RAI3_MOUSE
θ value	θ > 10 (rank : 96)	NC score	0.110733 (rank : 42)
Query Neighborhood Hits	90	Target Neighborhood Hits	20	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BHL4, Q8K067, Q8K1G5	Gene names	Gprc5a, Rai3, Raig1
Domain Architecture
Description	Retinoic acid-induced protein 3 (G-protein coupled receptor family C group 5 member A) (Retinoic acid-induced gene 1 protein) (RAIG-1).

Hits sorted by NC score

MGR1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	90	Target Neighborhood Hits	90	Shared Neighborhood Hits	90
SwissProt Accessions	P97772, Q6AXG4, Q9EPV6	Gene names	Grm1, Gprc1a, Mglur1
Domain Architecture
Description	Metabotropic glutamate receptor 1 precursor (mGluR1).

MGR1_HUMAN
NC score	0.997411 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	90	Target Neighborhood Hits	85	Shared Neighborhood Hits	57
SwissProt Accessions	Q13255, Q13256, Q14757, Q14758, Q5VTF7, Q5VTF8, Q9NU10, Q9UGS9, Q9UGT0	Gene names	GRM1, GPRC1A, MGLUR1
Domain Architecture
Description	Metabotropic glutamate receptor 1 precursor (mGluR1).

MGR5_HUMAN
NC score	0.992949 (rank : 3)	θ value	0 (rank : 4)
Query Neighborhood Hits	90	Target Neighborhood Hits	72	Shared Neighborhood Hits	45
SwissProt Accessions	P41594	Gene names	GRM5, GPRC1E, MGLUR5
Domain Architecture
Description	Metabotropic glutamate receptor 5 precursor (mGluR5).

MGR2_HUMAN
NC score	0.979508 (rank : 4)	θ value	0 (rank : 3)
Query Neighborhood Hits	90	Target Neighborhood Hits	56	Shared Neighborhood Hits	40
SwissProt Accessions	Q14416, Q52MC6, Q9H3N6	Gene names	GRM2, GPRC1B, MGLUR2
Domain Architecture
Description	Metabotropic glutamate receptor 2 precursor (mGluR2).

MGR3_HUMAN
NC score	0.976398 (rank : 5)	θ value	8.53067e-184 (rank : 5)
Query Neighborhood Hits	90	Target Neighborhood Hits	58	Shared Neighborhood Hits	40
SwissProt Accessions	Q14832, Q75MV4, Q75N17, Q86YG6, Q8TBH9	Gene names	GRM3, GPRC1C, MGLUR3
Domain Architecture
Description	Metabotropic glutamate receptor 3 precursor (mGluR3).

MGR3_MOUSE
NC score	0.976015 (rank : 6)	θ value	1.11414e-183 (rank : 6)
Query Neighborhood Hits	90	Target Neighborhood Hits	54	Shared Neighborhood Hits	39
SwissProt Accessions	Q9QYS2	Gene names	Grm3, Gprc1c, Mglur3
Domain Architecture
Description	Metabotropic glutamate receptor 3 precursor (mGluR3).

MGR4_HUMAN
NC score	0.975513 (rank : 7)	θ value	4.1007e-178 (rank : 7)
Query Neighborhood Hits	90	Target Neighborhood Hits	63	Shared Neighborhood Hits	42
SwissProt Accessions	Q14833, Q5SZ84	Gene names	GRM4, GPRC1D, MGLUR4
Domain Architecture
Description	Metabotropic glutamate receptor 4 precursor (mGluR4).

MGR6_HUMAN
NC score	0.973800 (rank : 8)	θ value	5.73535e-172 (rank : 13)
Query Neighborhood Hits	90	Target Neighborhood Hits	58	Shared Neighborhood Hits	37
SwissProt Accessions	O15303	Gene names	GRM6, GPRC1F, MGLUR6
Domain Architecture
Description	Metabotropic glutamate receptor 6 precursor (mGluR6).

MGR8_MOUSE
NC score	0.973737 (rank : 9)	θ value	1.11673e-175 (rank : 10)
Query Neighborhood Hits	90	Target Neighborhood Hits	44	Shared Neighborhood Hits	36
SwissProt Accessions	P47743, Q6B964	Gene names	Grm8, Gprc1h, Mglur8
Domain Architecture
Description	Metabotropic glutamate receptor 8 precursor (mGluR8).

MGR8_HUMAN
NC score	0.973701 (rank : 10)	θ value	5.01279e-176 (rank : 8)
Query Neighborhood Hits	90	Target Neighborhood Hits	49	Shared Neighborhood Hits	36
SwissProt Accessions	O00222, O15493, O95945, O95946, Q3MIV9, Q52M02, Q6J165	Gene names	GRM8, GPRC1H, MGLUR8
Domain Architecture
Description	Metabotropic glutamate receptor 8 precursor (mGluR8).

MGR6_MOUSE
NC score	0.972546 (rank : 11)	θ value	6.77497e-173 (rank : 12)
Query Neighborhood Hits	90	Target Neighborhood Hits	56	Shared Neighborhood Hits	35
SwissProt Accessions	Q5NCH9	Gene names	Grm6, Gprc1f, Mglur6
Domain Architecture	No domain graphic available
Description	Metabotropic glutamate receptor 6 precursor (mGluR6).

MGR7_HUMAN
NC score	0.972153 (rank : 12)	θ value	1.4585e-175 (rank : 11)
Query Neighborhood Hits	90	Target Neighborhood Hits	52	Shared Neighborhood Hits	34
SwissProt Accessions	Q14831, Q8NFS2, Q8NFS3, Q8NFS4	Gene names	GRM7, GPRC1G, MGLUR7
Domain Architecture
Description	Metabotropic glutamate receptor 7 precursor (mGluR7).

MGR7_MOUSE
NC score	0.972045 (rank : 13)	θ value	1.11673e-175 (rank : 9)
Query Neighborhood Hits	90	Target Neighborhood Hits	53	Shared Neighborhood Hits	34
SwissProt Accessions	Q68ED2	Gene names	Grm7, Gprc1g, Mglur7
Domain Architecture	No domain graphic available
Description	Metabotropic glutamate receptor 7 precursor (mGluR7).

CASR_HUMAN
NC score	0.943547 (rank : 14)	θ value	9.34977e-98 (rank : 14)
Query Neighborhood Hits	90	Target Neighborhood Hits	71	Shared Neighborhood Hits	41
SwissProt Accessions	P41180, Q13912, Q16108, Q16109, Q16110, Q16379, Q4PJ19	Gene names	CASR, GPRC2A, PCAR1
Domain Architecture
Description	Extracellular calcium-sensing receptor precursor (CaSR) (Parathyroid Cell calcium-sensing receptor).

CASR_MOUSE
NC score	0.943510 (rank : 15)	θ value	3.55291e-97 (rank : 15)
Query Neighborhood Hits	90	Target Neighborhood Hits	72	Shared Neighborhood Hits	41
SwissProt Accessions	Q9QY96, O08968, O88519, Q9QY95, Q9QZU8, Q9R1D6, Q9R1Y2	Gene names	Casr, Gprc2a
Domain Architecture
Description	Extracellular calcium-sensing receptor precursor (CaSR) (Parathyroid Cell calcium-sensing receptor).

V2RX_MOUSE
NC score	0.933672 (rank : 16)	θ value	2.47765e-74 (rank : 16)
Query Neighborhood Hits	90	Target Neighborhood Hits	45	Shared Neighborhood Hits	30
SwissProt Accessions	O70410	Gene names
Domain Architecture	No domain graphic available
Description	Vomeronasal type-2 receptor X precursor (Putative pheromone receptor V2RX).

V2R1B_MOUSE
NC score	0.920796 (rank : 17)	θ value	1.61718e-49 (rank : 24)
Query Neighborhood Hits	90	Target Neighborhood Hits	39	Shared Neighborhood Hits	26
SwissProt Accessions	Q6TAC4, O70409	Gene names	V2r1b
Domain Architecture	No domain graphic available
Description	Vomeronasal type-2 receptor 1b precursor (Putative pheromone receptor V2R1b).

GPC6A_HUMAN
NC score	0.915073 (rank : 18)	θ value	4.38363e-63 (rank : 19)
Query Neighborhood Hits	90	Target Neighborhood Hits	53	Shared Neighborhood Hits	34
SwissProt Accessions	Q5T6X5, Q6JK43, Q6JK44, Q8NGU8, Q8NHZ9, Q8TDT6	Gene names	GPRC6A, GPCR33
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor family C group 6 member A precursor (hGPRC6A) (G-protein coupled receptor 33) (hGPCR33).

GPC6A_MOUSE
NC score	0.913057 (rank : 19)	θ value	2.84138e-62 (rank : 20)
Query Neighborhood Hits	90	Target Neighborhood Hits	57	Shared Neighborhood Hits	34
SwissProt Accessions	Q8K4Z6, Q5DK51, Q5DK52	Gene names	Gprc6a
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor family C group 6 member A precursor.

TS1R2_MOUSE
NC score	0.908324 (rank : 20)	θ value	5.02714e-51 (rank : 22)
Query Neighborhood Hits	90	Target Neighborhood Hits	69	Shared Neighborhood Hits	41
SwissProt Accessions	Q925I4, Q923J8	Gene names	Tas1r2, Gpr71, T1r2, Tr2
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 2 precursor (G-protein coupled receptor 71) (Sweet taste receptor T1R2).

TS1R1_MOUSE
NC score	0.906602 (rank : 21)	θ value	1.2325e-65 (rank : 17)
Query Neighborhood Hits	90	Target Neighborhood Hits	57	Shared Neighborhood Hits	37
SwissProt Accessions	Q99PG6, Q6NS58, Q923J9, Q925I5, Q99PG5	Gene names	Tas1r1, Gpr70, T1r1, Tr1
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 1 precursor (G-protein coupled receptor 70).

TS1R1_HUMAN
NC score	0.906061 (rank : 22)	θ value	2.32439e-64 (rank : 18)
Query Neighborhood Hits	90	Target Neighborhood Hits	72	Shared Neighborhood Hits	33
SwissProt Accessions	Q7RTX1, Q8NGZ7, Q8TDJ7, Q8TDJ8, Q8TDJ9, Q8TDK0	Gene names	TAS1R1, GPR70, T1R1, TR1
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 1 precursor (G-protein coupled receptor 70) (Gm148).

TS1R2_HUMAN
NC score	0.904562 (rank : 23)	θ value	7.01481e-53 (rank : 21)
Query Neighborhood Hits	90	Target Neighborhood Hits	48	Shared Neighborhood Hits	38
SwissProt Accessions	Q8TE23, Q5TZ19	Gene names	TAS1R2, GPR71, T1R2, TR2
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 2 precursor (G-protein coupled receptor 71) (Sweet taste receptor T1R2).

TS1R3_MOUSE
NC score	0.893618 (rank : 24)	θ value	8.57503e-51 (rank : 23)
Query Neighborhood Hits	90	Target Neighborhood Hits	49	Shared Neighborhood Hits	32
SwissProt Accessions	Q925D8, Q91VA4, Q923K0, Q925A4, Q925D9	Gene names	Tas1r3, Sac, T1r3, Tr3
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 3 precursor (Sweet taste receptor T1R3) (Saccharin preference protein).

TS1R3_HUMAN
NC score	0.888386 (rank : 25)	θ value	4.86918e-46 (rank : 25)
Query Neighborhood Hits	90	Target Neighborhood Hits	46	Shared Neighborhood Hits	30
SwissProt Accessions	Q7RTX0, Q5TA49, Q8NGW9	Gene names	TAS1R3, T1R3, TR3
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 3 precursor (Sweet taste receptor T1R3).

GABR2_HUMAN
NC score	0.531294 (rank : 26)	θ value	1.29631e-06 (rank : 26)
Query Neighborhood Hits	90	Target Neighborhood Hits	101	Shared Neighborhood Hits	40
SwissProt Accessions	O75899, O75974, O75975, Q5VXZ2, Q8WX04, Q9P1R2, Q9UNR1, Q9UNS9	Gene names	GABBR2, GPR51, GPRC3B
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 2 precursor (GABA-B receptor 2) (GABA-B-R2) (Gb2) (GABABR2) (G-protein coupled receptor 51) (HG20).

GABR1_MOUSE
NC score	0.408653 (rank : 27)	θ value	1.43324e-05 (rank : 31)
Query Neighborhood Hits	90	Target Neighborhood Hits	139	Shared Neighborhood Hits	33
SwissProt Accessions	Q9WV18, Q9WU48, Q9WV15, Q9WV16, Q9WV17	Gene names	Gabbr1
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 1 precursor (GABA-B receptor 1) (GABA-B-R1) (Gb1).

GABR1_HUMAN
NC score	0.408627 (rank : 28)	θ value	1.43324e-05 (rank : 30)
Query Neighborhood Hits	90	Target Neighborhood Hits	142	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UBS5, O95375, O95468, O95975, O96022, Q86W60, Q9UQQ0	Gene names	GABBR1, GPRC3A
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 1 precursor (GABA-B receptor 1) (GABA-B-R1) (Gb1).

GPC5B_MOUSE
NC score	0.320249 (rank : 29)	θ value	0.000786445 (rank : 35)
Query Neighborhood Hits	90	Target Neighborhood Hits	33	Shared Neighborhood Hits	23
SwissProt Accessions	Q923Z0, Q8CCV3	Gene names	Gprc5b, Raig2
Domain Architecture
Description	G-protein coupled receptor family C group 5 member B precursor (Retinoic acid-induced gene 2 protein) (RAIG-2).

GPC5B_HUMAN
NC score	0.294890 (rank : 30)	θ value	0.00035302 (rank : 33)
Query Neighborhood Hits	90	Target Neighborhood Hits	28	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NZH0, O75205, Q8NBZ8	Gene names	GPRC5B, RAIG2
Domain Architecture
Description	G-protein coupled receptor family C group 5 member B precursor (Retinoic acid-induced gene 2 protein) (RAIG-2) (A-69G12.1).

GP158_HUMAN
NC score	0.246178 (rank : 31)	θ value	1.09739e-05 (rank : 28)
Query Neighborhood Hits	90	Target Neighborhood Hits	221	Shared Neighborhood Hits	24
SwissProt Accessions	Q5T848, Q6QR81, Q9ULT3	Gene names	GPR158, KIAA1136
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 158 precursor.

GP158_MOUSE
NC score	0.225011 (rank : 32)	θ value	0.000786445 (rank : 34)
Query Neighborhood Hits	90	Target Neighborhood Hits	82	Shared Neighborhood Hits	18
SwissProt Accessions	Q8C419, Q8CHB0	Gene names	Gpr158, Kiaa1136
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 158 precursor.

NMDZ1_MOUSE
NC score	0.201881 (rank : 33)	θ value	0.0113563 (rank : 40)
Query Neighborhood Hits	90	Target Neighborhood Hits	76	Shared Neighborhood Hits	38
SwissProt Accessions	P35438, Q8CFS4	Gene names	Grin1, Glurz1
Domain Architecture
Description	Glutamate [NMDA] receptor subunit zeta 1 precursor (N-methyl-D- aspartate receptor subunit NR1).

NMDZ1_HUMAN
NC score	0.198650 (rank : 34)	θ value	0.0431538 (rank : 43)
Query Neighborhood Hits	90	Target Neighborhood Hits	77	Shared Neighborhood Hits	38
SwissProt Accessions	Q05586, P35437, Q12867, Q12868	Gene names	GRIN1, NMDAR1
Domain Architecture
Description	Glutamate [NMDA] receptor subunit zeta 1 precursor (N-methyl-D- aspartate receptor subunit NR1).

GP179_HUMAN
NC score	0.198527 (rank : 35)	θ value	1.09739e-05 (rank : 29)
Query Neighborhood Hits	90	Target Neighborhood Hits	372	Shared Neighborhood Hits	21
SwissProt Accessions	Q6PRD1	Gene names	GPR179, GPR158L1
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 179 precursor (Probable G-protein coupled receptor 158-like 1).

GPC5C_MOUSE
NC score	0.181898 (rank : 36)	θ value	0.00134147 (rank : 36)
Query Neighborhood Hits	90	Target Neighborhood Hits	25	Shared Neighborhood Hits	17
SwissProt Accessions	Q8K3J9, Q8K0H0	Gene names	Gprc5c, Raig3
Domain Architecture
Description	G-protein coupled receptor family C group 5 member C precursor (Retinoic acid-induced gene 3 protein) (RAIG-3).

GPC5C_HUMAN
NC score	0.157541 (rank : 37)	θ value	0.21417 (rank : 48)
Query Neighborhood Hits	90	Target Neighborhood Hits	26	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NQ84, Q9NZG5	Gene names	GPRC5C, RAIG3
Domain Architecture
Description	G-protein coupled receptor family C group 5 member C precursor (Retinoic acid-induced gene 3 protein) (RAIG-3).

ANPRC_MOUSE
NC score	0.157327 (rank : 38)	θ value	2.21117e-06 (rank : 27)
Query Neighborhood Hits	90	Target Neighborhood Hits	27	Shared Neighborhood Hits	20
SwissProt Accessions	P70180, P97804, Q9R025, Q9R027, Q9R028	Gene names	Npr3
Domain Architecture
Description	Atrial natriuretic peptide clearance receptor precursor (ANP-C) (ANPRC) (NPR-C) (Atrial natriuretic peptide C-type receptor) (EF-2).

ANPRC_HUMAN
NC score	0.136380 (rank : 39)	θ value	0.000270298 (rank : 32)
Query Neighborhood Hits	90	Target Neighborhood Hits	27	Shared Neighborhood Hits	19
SwissProt Accessions	P17342	Gene names	NPR3, ANPRC
Domain Architecture
Description	Atrial natriuretic peptide clearance receptor precursor (ANP-C) (ANPRC) (NPR-C) (Atrial natriuretic peptide C-type receptor).

GP156_MOUSE
NC score	0.118974 (rank : 40)	θ value	θ > 10 (rank : 92)
Query Neighborhood Hits	90	Target Neighborhood Hits	95	Shared Neighborhood Hits	16
SwissProt Accessions	Q6PCP7, Q8K452	Gene names	Gpr156, Gababl
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 156 (GABAB-related G-protein coupled receptor).

GPC5D_MOUSE
NC score	0.117791 (rank : 41)	θ value	θ > 10 (rank : 94)
Query Neighborhood Hits	90	Target Neighborhood Hits	19	Shared Neighborhood Hits	12
SwissProt Accessions	Q9JIL6, Q8CJI0, Q8CJI1	Gene names	Gprc5d
Domain Architecture
Description	G-protein coupled receptor family C group 5 member D.

RAI3_MOUSE
NC score	0.110733 (rank : 42)	θ value	θ > 10 (rank : 96)
Query Neighborhood Hits	90	Target Neighborhood Hits	20	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BHL4, Q8K067, Q8K1G5	Gene names	Gprc5a, Rai3, Raig1
Domain Architecture
Description	Retinoic acid-induced protein 3 (G-protein coupled receptor family C group 5 member A) (Retinoic acid-induced gene 1 protein) (RAIG-1).

GP156_HUMAN
NC score	0.098249 (rank : 43)	θ value	θ > 10 (rank : 91)
Query Neighborhood Hits	90	Target Neighborhood Hits	84	Shared Neighborhood Hits	17
SwissProt Accessions	Q8NFN8, Q86SN6	Gene names	GPR156, GABABL, PGR28
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 156 (GABAB-related G-protein coupled receptor) (G-protein coupled receptor PGR28).

GPC5D_HUMAN
NC score	0.092498 (rank : 44)	θ value	θ > 10 (rank : 93)
Query Neighborhood Hits	90	Target Neighborhood Hits	21	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NZD1, Q3KNV3, Q7Z5J9, Q8TDS6	Gene names	GPRC5D
Domain Architecture
Description	G-protein coupled receptor family C group 5 member D.

RAI3_HUMAN
NC score	0.082972 (rank : 45)	θ value	θ > 10 (rank : 95)
Query Neighborhood Hits	90	Target Neighborhood Hits	17	Shared Neighborhood Hits	9
SwissProt Accessions	Q8NFJ5, O95357	Gene names	GPRC5A, RAI3, RAIG1
Domain Architecture
Description	Retinoic acid-induced protein 3 (G-protein coupled receptor family C group 5 member A) (Retinoic acid-induced gene 1 protein) (RAIG-1) (Orphan G-protein coupling receptor PEIG-1).

GRIK2_HUMAN
NC score	0.069019 (rank : 46)	θ value	0.0431538 (rank : 42)
Query Neighborhood Hits	90	Target Neighborhood Hits	50	Shared Neighborhood Hits	21
SwissProt Accessions	Q13002	Gene names	GRIK2, GLUR6
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 2 precursor (Glutamate receptor 6) (GluR-6) (GluR6) (Excitatory amino acid receptor 4) (EAA4).

GRIK1_MOUSE
NC score	0.068897 (rank : 47)	θ value	0.00228821 (rank : 39)
Query Neighborhood Hits	90	Target Neighborhood Hits	46	Shared Neighborhood Hits	20
SwissProt Accessions	Q60934	Gene names	Grik1, Glur5
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 1 precursor (Glutamate receptor 5) (GluR-5) (GluR5).

GRIK1_HUMAN
NC score	0.068709 (rank : 48)	θ value	0.00134147 (rank : 37)
Query Neighborhood Hits	90	Target Neighborhood Hits	48	Shared Neighborhood Hits	20
SwissProt Accessions	P39086, Q13001, Q86SU9	Gene names	GRIK1, GLUR5
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 1 precursor (Glutamate receptor 5) (GluR-5) (GluR5) (Excitatory amino acid receptor 3) (EAA3).

GUC2G_MOUSE
NC score	0.057305 (rank : 49)	θ value	0.00175202 (rank : 38)
Query Neighborhood Hits	90	Target Neighborhood Hits	644	Shared Neighborhood Hits	22
SwissProt Accessions	Q6TL19, Q8BWU7	Gene names	Gucy2g
Domain Architecture	No domain graphic available
Description	Guanylate cyclase 2G precursor (EC 4.6.1.2) (Guanylyl cyclase receptor G) (mGC-G).

GRIK3_HUMAN
NC score	0.043468 (rank : 50)	θ value	2.36792 (rank : 65)
Query Neighborhood Hits	90	Target Neighborhood Hits	41	Shared Neighborhood Hits	17
SwissProt Accessions	Q13003, Q13004, Q16136	Gene names	GRIK3, GLUR7
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 3 precursor (Glutamate receptor 7) (GluR-7) (GluR7) (Excitatory amino acid receptor 5) (EAA5).

BCAR1_MOUSE
NC score	0.041177 (rank : 51)	θ value	0.0252991 (rank : 41)
Query Neighborhood Hits	90	Target Neighborhood Hits	438	Shared Neighborhood Hits	11
SwissProt Accessions	Q61140, Q60869	Gene names	Bcar1, Cas, Crkas
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

NMD3A_HUMAN
NC score	0.039432 (rank : 52)	θ value	0.365318 (rank : 53)
Query Neighborhood Hits	90	Target Neighborhood Hits	58	Shared Neighborhood Hits	13
SwissProt Accessions	Q8TCU5, Q8TF29, Q8WXI6	Gene names	GRIN3A, KIAA1973
Domain Architecture	No domain graphic available
Description	Glutamate [NMDA] receptor subunit 3A precursor (N-methyl-D-aspartate receptor subtype NR3A) (NMDAR-L).

NMDE2_MOUSE
NC score	0.034412 (rank : 53)	θ value	2.36792 (rank : 68)
Query Neighborhood Hits	90	Target Neighborhood Hits	64	Shared Neighborhood Hits	16
SwissProt Accessions	Q01097, Q9DCB2	Gene names	Grin2b
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 2 precursor (N-methyl D- aspartate receptor subtype 2B) (NR2B) (NMDAR2B).

NMDE2_HUMAN
NC score	0.034134 (rank : 54)	θ value	2.36792 (rank : 67)
Query Neighborhood Hits	90	Target Neighborhood Hits	65	Shared Neighborhood Hits	14
SwissProt Accessions	Q13224, Q12919, Q13220, Q13225, Q9UM56	Gene names	GRIN2B
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 2 precursor (N-methyl D- aspartate receptor subtype 2B) (NR2B) (NMDAR2B) (N-methyl-D-aspartate receptor subunit 3) (NR3) (hNR3).

NMD3B_HUMAN
NC score	0.032649 (rank : 55)	θ value	3.0926 (rank : 71)
Query Neighborhood Hits	90	Target Neighborhood Hits	55	Shared Neighborhood Hits	12
SwissProt Accessions	O60391, Q5EAK7, Q7RTW9	Gene names	GRIN3B
Domain Architecture	No domain graphic available
Description	Glutamate [NMDA] receptor subunit 3B precursor (N-methyl-D-aspartate receptor subtype NR3B) (NR3B) (NMDAR3B).

BCAR1_HUMAN
NC score	0.032286 (rank : 56)	θ value	0.365318 (rank : 51)
Query Neighborhood Hits	90	Target Neighborhood Hits	554	Shared Neighborhood Hits	12
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

U258_HUMAN
NC score	0.021118 (rank : 57)	θ value	6.88961 (rank : 85)
Query Neighborhood Hits	90	Target Neighborhood Hits	6	Shared Neighborhood Hits	3
SwissProt Accessions	P59773	Gene names
Domain Architecture	No domain graphic available
Description	UPF0258 protein.

GR65_MOUSE
NC score	0.021052 (rank : 58)	θ value	0.163984 (rank : 47)
Query Neighborhood Hits	90	Target Neighborhood Hits	54	Shared Neighborhood Hits	4
SwissProt Accessions	Q91X51, Q9D3L9	Gene names	Gorasp1
Domain Architecture	No domain graphic available
Description	Golgi reassembly-stacking protein 1 (Golgi reassembly-stacking protein of 65 kDa) (GRASP65) (Golgi peripheral membrane protein p65).

LZTR1_MOUSE
NC score	0.016567 (rank : 59)	θ value	0.21417 (rank : 49)
Query Neighborhood Hits	90	Target Neighborhood Hits	200	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CQ33	Gene names	Lztr1, Tcfl2
Domain Architecture
Description	Leucine-zipper-like transcriptional regulator 1 (LZTR-1).

NCOA6_MOUSE
NC score	0.016466 (rank : 60)	θ value	0.47712 (rank : 55)
Query Neighborhood Hits	90	Target Neighborhood Hits	1076	Shared Neighborhood Hits	24
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

CRSP3_HUMAN
NC score	0.015915 (rank : 61)	θ value	5.27518 (rank : 75)
Query Neighborhood Hits	90	Target Neighborhood Hits	21	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ULK4, O95403, Q9H0J2, Q9NTT9, Q9NTU0, Q9Y5P7, Q9Y667	Gene names	CRSP3, ARC130, DRIP130, KIAA1216, SUR2
Domain Architecture	No domain graphic available
Description	CRSP complex subunit 3 (Cofactor required for Sp1 transcriptional activation subunit 3) (Transcriptional coactivator CRSP130) (Vitamin D3 receptor-interacting protein complex 130 kDa component) (DRIP130) (Activator-recruited cofactor 130 kDa component) (ARC130).

LZTR1_HUMAN
NC score	0.015106 (rank : 62)	θ value	0.62314 (rank : 56)
Query Neighborhood Hits	90	Target Neighborhood Hits	196	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N653, Q14776	Gene names	LZTR1, TCFL2
Domain Architecture
Description	Leucine-zipper-like transcriptional regulator 1 (LZTR-1).

ECM1_MOUSE
NC score	0.014934 (rank : 63)	θ value	1.38821 (rank : 59)
Query Neighborhood Hits	90	Target Neighborhood Hits	105	Shared Neighborhood Hits	5
SwissProt Accessions	Q61508	Gene names	Ecm1
Domain Architecture
Description	Extracellular matrix protein 1 precursor (Secretory component p85).

NCOA6_HUMAN
NC score	0.014276 (rank : 64)	θ value	0.62314 (rank : 57)
Query Neighborhood Hits	90	Target Neighborhood Hits	1202	Shared Neighborhood Hits	21
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

NFAC2_HUMAN
NC score	0.013645 (rank : 65)	θ value	1.38821 (rank : 61)
Query Neighborhood Hits	90	Target Neighborhood Hits	101	Shared Neighborhood Hits	6
SwissProt Accessions	Q13469, Q13468, Q5TFW7, Q5TFW8, Q9NPX6, Q9NQH3, Q9UJR2	Gene names	NFATC2, NFAT1, NFATP
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 2 (T cell transcription factor NFAT1) (NFAT pre-existing subunit) (NF-ATp).

HSF1_MOUSE
NC score	0.013453 (rank : 66)	θ value	0.47712 (rank : 54)
Query Neighborhood Hits	90	Target Neighborhood Hits	267	Shared Neighborhood Hits	6
SwissProt Accessions	P38532, O70462	Gene names	Hsf1
Domain Architecture
Description	Heat shock factor protein 1 (HSF 1) (Heat shock transcription factor 1) (HSTF 1).

NFAC2_MOUSE
NC score	0.013178 (rank : 67)	θ value	1.38821 (rank : 62)
Query Neighborhood Hits	90	Target Neighborhood Hits	98	Shared Neighborhood Hits	4
SwissProt Accessions	Q60591, Q60984, Q60985	Gene names	Nfatc2, Nfat1, Nfatp
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 2 (T cell transcription factor NFAT1) (NFAT pre-existing subunit) (NF-ATp).

NPAS4_MOUSE
NC score	0.012736 (rank : 68)	θ value	1.81305 (rank : 64)
Query Neighborhood Hits	90	Target Neighborhood Hits	245	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BGD7, Q3V3U3	Gene names	Npas4, Nxf
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF) (Limbic-enhanced PAS protein) (LE-PAS).

NPAS4_HUMAN
NC score	0.011815 (rank : 69)	θ value	2.36792 (rank : 69)
Query Neighborhood Hits	90	Target Neighborhood Hits	214	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IUM7, Q8N8S5, Q8N9Q9	Gene names	NPAS4, NXF
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF).

LTBP2_MOUSE
NC score	0.011422 (rank : 70)	θ value	1.81305 (rank : 63)
Query Neighborhood Hits	90	Target Neighborhood Hits	617	Shared Neighborhood Hits	15
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

MAP1A_HUMAN
NC score	0.010565 (rank : 71)	θ value	0.365318 (rank : 52)
Query Neighborhood Hits	90	Target Neighborhood Hits	1626	Shared Neighborhood Hits	15
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

RGS3_MOUSE
NC score	0.010183 (rank : 72)	θ value	0.279714 (rank : 50)
Query Neighborhood Hits	90	Target Neighborhood Hits	1621	Shared Neighborhood Hits	23
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

LTBP2_HUMAN
NC score	0.008258 (rank : 73)	θ value	5.27518 (rank : 76)
Query Neighborhood Hits	90	Target Neighborhood Hits	552	Shared Neighborhood Hits	12
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

MKL1_MOUSE
NC score	0.007885 (rank : 74)	θ value	2.36792 (rank : 66)
Query Neighborhood Hits	90	Target Neighborhood Hits	667	Shared Neighborhood Hits	13
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

CSKI2_MOUSE
NC score	0.007813 (rank : 75)	θ value	0.0736092 (rank : 45)
Query Neighborhood Hits	90	Target Neighborhood Hits	812	Shared Neighborhood Hits	16
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

AKAP3_MOUSE
NC score	0.007698 (rank : 76)	θ value	4.03905 (rank : 72)
Query Neighborhood Hits	90	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	O88987	Gene names	Akap3, Akap110
Domain Architecture
Description	A-kinase anchor protein 3 (Protein kinase A-anchoring protein 3) (PRKA3) (A-kinase anchor protein 110 kDa) (AKAP 110).

CO5_HUMAN
NC score	0.006952 (rank : 77)	θ value	6.88961 (rank : 82)
Query Neighborhood Hits	90	Target Neighborhood Hits	25	Shared Neighborhood Hits	4
SwissProt Accessions	P01031	Gene names	C5
Domain Architecture
Description	Complement C5 precursor [Contains: Complement C5 beta chain; Complement C5 alpha chain; C5a anaphylatoxin; Complement C5 alpha' chain].

ZIM10_HUMAN
NC score	0.005102 (rank : 78)	θ value	5.27518 (rank : 79)
Query Neighborhood Hits	90	Target Neighborhood Hits	577	Shared Neighborhood Hits	13
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

NOTC2_MOUSE
NC score	0.005021 (rank : 79)	θ value	0.0563607 (rank : 44)
Query Neighborhood Hits	90	Target Neighborhood Hits	1069	Shared Neighborhood Hits	12
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

UB7I1_MOUSE
NC score	0.004145 (rank : 80)	θ value	8.99809 (rank : 89)
Query Neighborhood Hits	90	Target Neighborhood Hits	206	Shared Neighborhood Hits	6
SwissProt Accessions	P58283, Q3U493, Q3UE56, Q3UGM3, Q68FN0, Q6P1H8, Q6PWY5, Q8BN27, Q8C1U3	Gene names	Ubce7ip1, Triad3, Uip83, Zin
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase TRIAD3 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (UbcM4-interacting protein 83) (Triad domain- containing protein 3).

MLL3_MOUSE
NC score	0.003801 (rank : 81)	θ value	4.03905 (rank : 74)
Query Neighborhood Hits	90	Target Neighborhood Hits	1399	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

AFAD_HUMAN
NC score	0.003739 (rank : 82)	θ value	3.0926 (rank : 70)
Query Neighborhood Hits	90	Target Neighborhood Hits	689	Shared Neighborhood Hits	6
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

COFA1_HUMAN
NC score	0.003482 (rank : 83)	θ value	6.88961 (rank : 83)
Query Neighborhood Hits	90	Target Neighborhood Hits	292	Shared Neighborhood Hits	9
SwissProt Accessions	P39059, Q5T6J4, Q9Y4W4	Gene names	COL15A1
Domain Architecture
Description	Collagen alpha-1(XV) chain precursor [Contains: Endostatin (Endostatin-XV) (Restin) (Related to endostatin)].

GAK19_HUMAN
NC score	0.003078 (rank : 84)	θ value	8.99809 (rank : 87)
Query Neighborhood Hits	90	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	P62691	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_4p16.1 provirus ancestral Gag polyprotein (Gag polyprotein).

NOTC2_HUMAN
NC score	0.002902 (rank : 85)	θ value	5.27518 (rank : 77)
Query Neighborhood Hits	90	Target Neighborhood Hits	1113	Shared Neighborhood Hits	12
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

LR37A_HUMAN
NC score	0.002820 (rank : 86)	θ value	6.88961 (rank : 84)
Query Neighborhood Hits	90	Target Neighborhood Hits	720	Shared Neighborhood Hits	15
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

CD248_MOUSE
NC score	0.002550 (rank : 87)	θ value	8.99809 (rank : 86)
Query Neighborhood Hits	90	Target Neighborhood Hits	578	Shared Neighborhood Hits	13
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

ZF106_MOUSE
NC score	0.002025 (rank : 88)	θ value	8.99809 (rank : 90)
Query Neighborhood Hits	90	Target Neighborhood Hits	472	Shared Neighborhood Hits	9
SwissProt Accessions	O88466, O55185, O88465, O88467, Q792M1, Q792P4, Q8CDZ8, Q8R3I4, Q9ESU3	Gene names	Zfp106, H3a, Sh3bp3, Sirm, Znf474
Domain Architecture	No domain graphic available
Description	Zinc finger protein 106 (Zfp-106) (Zinc finger protein 474) (H3a minor histocompatibility antigen) (Son of insulin receptor mutant).

SSBP4_HUMAN
NC score	0.001194 (rank : 89)	θ value	8.99809 (rank : 88)
Query Neighborhood Hits	90	Target Neighborhood Hits	753	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

PAX3_MOUSE
NC score	-0.000563 (rank : 90)	θ value	5.27518 (rank : 78)
Query Neighborhood Hits	90	Target Neighborhood Hits	478	Shared Neighborhood Hits	5
SwissProt Accessions	P24610, Q3UFQ9, Q8BRE7, Q9CXI6	Gene names	Pax3, Pax-3
Domain Architecture
Description	Paired box protein Pax-3.

CE152_HUMAN
NC score	-0.000650 (rank : 91)	θ value	6.88961 (rank : 81)
Query Neighborhood Hits	90	Target Neighborhood Hits	976	Shared Neighborhood Hits	5
SwissProt Accessions	O94986, Q6NTA0	Gene names	CEP152, KIAA0912
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 152 kDa (Cep152 protein).

PRD14_HUMAN
NC score	-0.000869 (rank : 92)	θ value	0.0961366 (rank : 46)
Query Neighborhood Hits	90	Target Neighborhood Hits	757	Shared Neighborhood Hits	5
SwissProt Accessions	Q9GZV8, Q86UX9	Gene names	PRDM14
Domain Architecture
Description	PR domain zinc finger protein 14 (PR domain-containing protein 14).

ZN516_MOUSE
NC score	-0.001269 (rank : 93)	θ value	1.06291 (rank : 58)
Query Neighborhood Hits	90	Target Neighborhood Hits	1197	Shared Neighborhood Hits	13
SwissProt Accessions	Q7TSH3	Gene names	Znf516, Kiaa0222, Zfp516
Domain Architecture
Description	Zinc finger protein 516.

GLIS3_MOUSE
NC score	-0.001723 (rank : 94)	θ value	1.38821 (rank : 60)
Query Neighborhood Hits	90	Target Neighborhood Hits	861	Shared Neighborhood Hits	7
SwissProt Accessions	Q6XP49, Q8BI60	Gene names	Glis3
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLIS3 (GLI-similar 3).

CCD21_HUMAN
NC score	-0.002535 (rank : 95)	θ value	6.88961 (rank : 80)
Query Neighborhood Hits	90	Target Neighborhood Hits	1228	Shared Neighborhood Hits	8
SwissProt Accessions	Q6P2H3, Q5VY68, Q5VY70, Q9H6Q1, Q9H828, Q9UF52	Gene names	CCDC21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

MAST2_HUMAN
NC score	-0.003887 (rank : 96)	θ value	4.03905 (rank : 73)
Query Neighborhood Hits	90	Target Neighborhood Hits	1189	Shared Neighborhood Hits	10
SwissProt Accessions	Q6P0Q8, O94899, Q5VT07, Q5VT08, Q7LGC4, Q8NDG1, Q96B94, Q9BYE8	Gene names	MAST2, KIAA0807, MAST205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).