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Network neighborhood for query Sequence : NFAC2_HUMAN

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NFAC2_HUMAN
SwissProt Accessions	Q13469, Q13468, Q5TFW7, Q5TFW8, Q9NPX6, Q9NQH3, Q9UJR2	Gene names	NFATC2, NFAT1, NFATP
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 2 (T cell transcription factor NFAT1) (NFAT pre-existing subunit) (NF-ATp).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

NFAC2_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	101	Target Neighborhood Hits	101	Shared Neighborhood Hits	101
SwissProt Accessions	Q13469, Q13468, Q5TFW7, Q5TFW8, Q9NPX6, Q9NQH3, Q9UJR2	Gene names	NFATC2, NFAT1, NFATP
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 2 (T cell transcription factor NFAT1) (NFAT pre-existing subunit) (NF-ATp).

NFAC2_MOUSE
θ value	0 (rank : 2)	NC score	0.983153 (rank : 2)
Query Neighborhood Hits	101	Target Neighborhood Hits	98	Shared Neighborhood Hits	27
SwissProt Accessions	Q60591, Q60984, Q60985	Gene names	Nfatc2, Nfat1, Nfatp
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 2 (T cell transcription factor NFAT1) (NFAT pre-existing subunit) (NF-ATp).

NFAC1_HUMAN
θ value	5.76203e-156 (rank : 3)	NC score	0.922299 (rank : 7)
Query Neighborhood Hits	101	Target Neighborhood Hits	312	Shared Neighborhood Hits	33
SwissProt Accessions	O95644, Q12865, Q15793	Gene names	NFATC1, NFAT2, NFATC
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 1 (NFAT transcription complex cytosolic component) (NF-ATc1) (NF-ATc).

NFAC1_MOUSE
θ value	3.28708e-135 (rank : 4)	NC score	0.948528 (rank : 3)
Query Neighborhood Hits	101	Target Neighborhood Hits	92	Shared Neighborhood Hits	15
SwissProt Accessions	O88942, O70345	Gene names	Nfatc1, Nfat2, Nfatc
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 1 (NFAT transcription complex cytosolic component) (NF-ATc1) (NF-ATc).

NFAC3_HUMAN
θ value	8.41738e-115 (rank : 5)	NC score	0.927376 (rank : 5)
Query Neighborhood Hits	101	Target Neighborhood Hits	102	Shared Neighborhood Hits	14
SwissProt Accessions	Q12968, O75211, Q14516, Q99840, Q99841, Q99842	Gene names	NFATC3, NFAT4
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 3 (NF-ATc3) (NFATc3) (T cell transcription factor NFAT4) (NF-AT4) (NFATx).

NFAC3_MOUSE
θ value	2.44908e-114 (rank : 6)	NC score	0.926087 (rank : 6)
Query Neighborhood Hits	101	Target Neighborhood Hits	106	Shared Neighborhood Hits	17
SwissProt Accessions	P97305, Q60896	Gene names	Nfatc3, Nfat4
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 3 (NF-ATc3) (NFATc3) (T cell transcription factor NFAT4) (NF-AT4) (NFATx).

NFAC4_HUMAN
θ value	1.0648e-109 (rank : 7)	NC score	0.930044 (rank : 4)
Query Neighborhood Hits	101	Target Neighborhood Hits	165	Shared Neighborhood Hits	18
SwissProt Accessions	Q14934	Gene names	NFATC4, NFAT3
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 4 (NF-ATc4) (NFATc4) (T cell transcription factor NFAT3) (NF-AT3).

NFAT5_MOUSE
θ value	1.23536e-57 (rank : 8)	NC score	0.823856 (rank : 8)
Query Neighborhood Hits	101	Target Neighborhood Hits	162	Shared Neighborhood Hits	19
SwissProt Accessions	Q9WV30	Gene names	Nfat5
Domain Architecture
Description	Nuclear factor of activated T-cells 5 (T cell transcription factor NFAT5) (NF-AT5) (Rel domain-containing transcription factor NFAT5).

NFAT5_HUMAN
θ value	1.61343e-57 (rank : 9)	NC score	0.805583 (rank : 9)
Query Neighborhood Hits	101	Target Neighborhood Hits	217	Shared Neighborhood Hits	20
SwissProt Accessions	O94916, O95693, Q9UN18	Gene names	NFAT5, KIAA0827, TONEBP
Domain Architecture
Description	Nuclear factor of activated T-cells 5 (T-cell transcription factor NFAT5) (NF-AT5) (Tonicity-responsive enhancer-binding protein) (TonE- binding protein) (TonEBP).

AUTS2_HUMAN
θ value	0.00665767 (rank : 10)	NC score	0.098914 (rank : 12)
Query Neighborhood Hits	101	Target Neighborhood Hits	342	Shared Neighborhood Hits	26
SwissProt Accessions	Q8WXX7, Q9Y4F2	Gene names	AUTS2, KIAA0442
Domain Architecture	No domain graphic available
Description	Autism susceptibility gene 2 protein.

PHC3_HUMAN
θ value	0.00665767 (rank : 11)	NC score	0.070741 (rank : 14)
Query Neighborhood Hits	101	Target Neighborhood Hits	218	Shared Neighborhood Hits	15
SwissProt Accessions	Q8NDX5, Q5HYF0, Q6NSG2, Q8NFT7, Q8NFZ1, Q8TBM2, Q9H971, Q9H9I4	Gene names	PHC3, EDR3, PH3
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 3 (hPH3) (Homolog of polyhomeotic 3) (Early development regulatory protein 3).

PHC3_MOUSE
θ value	0.00869519 (rank : 12)	NC score	0.069417 (rank : 15)
Query Neighborhood Hits	101	Target Neighborhood Hits	194	Shared Neighborhood Hits	14
SwissProt Accessions	Q8CHP6, Q3TLV5	Gene names	Phc3
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 3.

ATX1_HUMAN
θ value	0.163984 (rank : 13)	NC score	0.039383 (rank : 30)
Query Neighborhood Hits	101	Target Neighborhood Hits	79	Shared Neighborhood Hits	10
SwissProt Accessions	P54253, Q9UJG2, Q9Y4J1	Gene names	ATXN1, ATX1, SCA1
Domain Architecture
Description	Ataxin-1 (Spinocerebellar ataxia type 1 protein).

MAST4_HUMAN
θ value	0.163984 (rank : 14)	NC score	0.009974 (rank : 79)
Query Neighborhood Hits	101	Target Neighborhood Hits	1804	Shared Neighborhood Hits	48
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

BAG3_HUMAN
θ value	0.279714 (rank : 15)	NC score	0.034744 (rank : 34)
Query Neighborhood Hits	101	Target Neighborhood Hits	314	Shared Neighborhood Hits	24
SwissProt Accessions	O95817, Q9NT20, Q9P120	Gene names	BAG3, BIS
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1).

LMBL3_MOUSE
θ value	0.279714 (rank : 16)	NC score	0.039795 (rank : 29)
Query Neighborhood Hits	101	Target Neighborhood Hits	212	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BLB7, Q641L7, Q6ZPI2, Q8C0G4	Gene names	L3mbtl3
Domain Architecture	No domain graphic available
Description	Lethal(3)malignant brain tumor-like 3 protein (L(3)mbt-like 3 protein).

SRRM2_MOUSE
θ value	0.279714 (rank : 17)	NC score	0.038009 (rank : 32)
Query Neighborhood Hits	101	Target Neighborhood Hits	1470	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

ATN1_HUMAN
θ value	0.365318 (rank : 18)	NC score	0.041890 (rank : 27)
Query Neighborhood Hits	101	Target Neighborhood Hits	676	Shared Neighborhood Hits	42
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

RGS3_MOUSE
θ value	0.365318 (rank : 19)	NC score	0.046347 (rank : 25)
Query Neighborhood Hits	101	Target Neighborhood Hits	1621	Shared Neighborhood Hits	66
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

ARI1A_HUMAN
θ value	0.47712 (rank : 20)	NC score	0.059626 (rank : 19)
Query Neighborhood Hits	101	Target Neighborhood Hits	787	Shared Neighborhood Hits	41
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

BSN_MOUSE
θ value	0.47712 (rank : 21)	NC score	0.061564 (rank : 18)
Query Neighborhood Hits	101	Target Neighborhood Hits	2057	Shared Neighborhood Hits	69
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

NCOA6_HUMAN
θ value	0.62314 (rank : 22)	NC score	0.068887 (rank : 17)
Query Neighborhood Hits	101	Target Neighborhood Hits	1202	Shared Neighborhood Hits	70
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

NCOA6_MOUSE
θ value	0.62314 (rank : 23)	NC score	0.069282 (rank : 16)
Query Neighborhood Hits	101	Target Neighborhood Hits	1076	Shared Neighborhood Hits	68
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

HGS_HUMAN
θ value	0.813845 (rank : 24)	NC score	0.029353 (rank : 44)
Query Neighborhood Hits	101	Target Neighborhood Hits	517	Shared Neighborhood Hits	24
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

CO3A1_MOUSE
θ value	1.06291 (rank : 25)	NC score	0.016661 (rank : 63)
Query Neighborhood Hits	101	Target Neighborhood Hits	466	Shared Neighborhood Hits	24
SwissProt Accessions	P08121, Q61429, Q9CRN7	Gene names	Col3a1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

FIGN_HUMAN
θ value	1.06291 (rank : 26)	NC score	0.017900 (rank : 60)
Query Neighborhood Hits	101	Target Neighborhood Hits	176	Shared Neighborhood Hits	17
SwissProt Accessions	Q5HY92, Q9H6M5, Q9NVZ9	Gene names	FIGN
Domain Architecture	No domain graphic available
Description	Fidgetin.

RHG09_HUMAN
θ value	1.06291 (rank : 27)	NC score	0.021478 (rank : 54)
Query Neighborhood Hits	101	Target Neighborhood Hits	186	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BRR9, Q8TCJ3, Q8WYR0, Q96EZ2, Q96S74	Gene names	ARHGAP9
Domain Architecture
Description	Rho-GTPase-activating protein 9.

MGR1_MOUSE
θ value	1.38821 (rank : 28)	NC score	0.013645 (rank : 71)
Query Neighborhood Hits	101	Target Neighborhood Hits	90	Shared Neighborhood Hits	6
SwissProt Accessions	P97772, Q6AXG4, Q9EPV6	Gene names	Grm1, Gprc1a, Mglur1
Domain Architecture
Description	Metabotropic glutamate receptor 1 precursor (mGluR1).

SP5_HUMAN
θ value	1.38821 (rank : 29)	NC score	0.004488 (rank : 94)
Query Neighborhood Hits	101	Target Neighborhood Hits	832	Shared Neighborhood Hits	16
SwissProt Accessions	Q6BEB4	Gene names	SP5
Domain Architecture	No domain graphic available
Description	Transcription factor Sp5.

SP5_MOUSE
θ value	1.38821 (rank : 30)	NC score	0.004661 (rank : 93)
Query Neighborhood Hits	101	Target Neighborhood Hits	821	Shared Neighborhood Hits	17
SwissProt Accessions	Q9JHX2	Gene names	Sp5
Domain Architecture
Description	Transcription factor Sp5.

SRRM1_MOUSE
θ value	1.38821 (rank : 31)	NC score	0.047793 (rank : 24)
Query Neighborhood Hits	101	Target Neighborhood Hits	966	Shared Neighborhood Hits	47
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

CASL_HUMAN
θ value	1.81305 (rank : 32)	NC score	0.016333 (rank : 65)
Query Neighborhood Hits	101	Target Neighborhood Hits	259	Shared Neighborhood Hits	13
SwissProt Accessions	Q14511	Gene names	NEDD9, CASL
Domain Architecture
Description	Enhancer of filamentation 1 (HEF1) (CRK-associated substrate-related protein) (CAS-L) (CasL) (p105) (Protein NEDD9) (NY-REN-12 antigen).

CO4A6_HUMAN
θ value	1.81305 (rank : 33)	NC score	0.011217 (rank : 75)
Query Neighborhood Hits	101	Target Neighborhood Hits	318	Shared Neighborhood Hits	17
SwissProt Accessions	Q14031, Q12823, Q14053, Q5JYH6, Q9NQM5, Q9NTX3, Q9UJ76, Q9UMG6, Q9Y4L4	Gene names	COL4A6
Domain Architecture
Description	Collagen alpha-6(IV) chain precursor.

CSF1_HUMAN
θ value	1.81305 (rank : 34)	NC score	0.024085 (rank : 50)
Query Neighborhood Hits	101	Target Neighborhood Hits	258	Shared Neighborhood Hits	15
SwissProt Accessions	P09603, Q13130, Q14086, Q14806, Q9UQR8	Gene names	CSF1
Domain Architecture
Description	Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF) (M- CSF) (Lanimostim).

MBD5_HUMAN
θ value	1.81305 (rank : 35)	NC score	0.059582 (rank : 20)
Query Neighborhood Hits	101	Target Neighborhood Hits	176	Shared Neighborhood Hits	19
SwissProt Accessions	Q9P267, Q9NUV6	Gene names	MBD5, KIAA1461
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 5 (Methyl-CpG-binding protein MBD5).

SMAD9_HUMAN
θ value	1.81305 (rank : 36)	NC score	0.016720 (rank : 62)
Query Neighborhood Hits	101	Target Neighborhood Hits	48	Shared Neighborhood Hits	7
SwissProt Accessions	O15198, O14989	Gene names	SMAD9, MADH6, MADH9
Domain Architecture
Description	Mothers against decapentaplegic homolog 9 (SMAD 9) (Mothers against DPP homolog 9) (Smad9) (Madh6).

TSNA1_HUMAN
θ value	1.81305 (rank : 37)	NC score	0.035378 (rank : 33)
Query Neighborhood Hits	101	Target Neighborhood Hits	178	Shared Neighborhood Hits	10
SwissProt Accessions	Q96NA8	Gene names	TSNARE1
Domain Architecture	No domain graphic available
Description	t-SNARE domain-containing protein 1.

KBTB9_MOUSE
θ value	2.36792 (rank : 38)	NC score	0.006754 (rank : 91)
Query Neighborhood Hits	101	Target Neighborhood Hits	197	Shared Neighborhood Hits	9
SwissProt Accessions	Q80T74	Gene names	Kbtbd9, Kiaa1921
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 9.

TR13C_HUMAN
θ value	2.36792 (rank : 39)	NC score	0.031831 (rank : 36)
Query Neighborhood Hits	101	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	Q96RJ3	Gene names	TNFRSF13C, BAFFR, BR3
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 13C (B cell- activating factor receptor) (BAFF receptor) (BAFF-R) (BLyS receptor 3) (CD268 antigen).

BCL9_HUMAN
θ value	3.0926 (rank : 40)	NC score	0.040126 (rank : 28)
Query Neighborhood Hits	101	Target Neighborhood Hits	1008	Shared Neighborhood Hits	51
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

CN092_MOUSE
θ value	3.0926 (rank : 41)	NC score	0.016262 (rank : 66)
Query Neighborhood Hits	101	Target Neighborhood Hits	206	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BU11, Q80UI2, Q99PN9, Q9CS16	Gene names
Domain Architecture
Description	Epidermal Langerhans cell protein LCP1.

LAT_MOUSE
θ value	3.0926 (rank : 42)	NC score	0.038448 (rank : 31)
Query Neighborhood Hits	101	Target Neighborhood Hits	31	Shared Neighborhood Hits	5
SwissProt Accessions	O54957	Gene names	Lat
Domain Architecture	No domain graphic available
Description	Linker for activation of T-cells family member 1 (36 kDa phospho- tyrosine adapter protein) (pp36) (p36-38).

MINT_HUMAN
θ value	3.0926 (rank : 43)	NC score	0.020770 (rank : 55)
Query Neighborhood Hits	101	Target Neighborhood Hits	1291	Shared Neighborhood Hits	42
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

PHLB1_HUMAN
θ value	3.0926 (rank : 44)	NC score	0.011393 (rank : 74)
Query Neighborhood Hits	101	Target Neighborhood Hits	1038	Shared Neighborhood Hits	27
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

SI1L3_HUMAN
θ value	3.0926 (rank : 45)	NC score	0.030153 (rank : 42)
Query Neighborhood Hits	101	Target Neighborhood Hits	305	Shared Neighborhood Hits	23
SwissProt Accessions	O60292, Q2TV87	Gene names	SIPA1L3, KIAA0545, SPAL3
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 3 (SPA-1-like protein 3).

TARA_HUMAN
θ value	3.0926 (rank : 46)	NC score	0.031701 (rank : 37)
Query Neighborhood Hits	101	Target Neighborhood Hits	1626	Shared Neighborhood Hits	52
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

AAK1_HUMAN
θ value	4.03905 (rank : 47)	NC score	0.012221 (rank : 73)
Query Neighborhood Hits	101	Target Neighborhood Hits	1077	Shared Neighborhood Hits	34
SwissProt Accessions	Q2M2I8, Q4ZFZ3, Q53RX6, Q9UPV4	Gene names	AAK1, KIAA1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

CD008_HUMAN
θ value	4.03905 (rank : 48)	NC score	0.025809 (rank : 46)
Query Neighborhood Hits	101	Target Neighborhood Hits	330	Shared Neighborhood Hits	17
SwissProt Accessions	P78312, O43607, P78311, P78313, Q9UEG8	Gene names	C4orf8
Domain Architecture	No domain graphic available
Description	Protein C4orf8 (Protein IT14).

COE4_MOUSE
θ value	4.03905 (rank : 49)	NC score	0.008786 (rank : 83)
Query Neighborhood Hits	101	Target Neighborhood Hits	29	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K4J2, Q8K4J1, Q8K4J3, Q8K4J4, Q8K4J5	Gene names	Ebf4, Coe4
Domain Architecture
Description	Transcription factor COE4 (Early B-cell factor 4) (EBF-4) (Olf-1/EBF- like 4) (OE-4) (O/E-4).

DLG5_HUMAN
θ value	4.03905 (rank : 50)	NC score	0.004413 (rank : 96)
Query Neighborhood Hits	101	Target Neighborhood Hits	1088	Shared Neighborhood Hits	15
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

DNMBP_MOUSE
θ value	4.03905 (rank : 51)	NC score	0.008479 (rank : 84)
Query Neighborhood Hits	101	Target Neighborhood Hits	435	Shared Neighborhood Hits	10
SwissProt Accessions	Q6TXD4, Q6ZQ05, Q8CEW8, Q8R0Y2	Gene names	Dnmbp, Kiaa1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

EWS_HUMAN
θ value	4.03905 (rank : 52)	NC score	0.030174 (rank : 41)
Query Neighborhood Hits	101	Target Neighborhood Hits	249	Shared Neighborhood Hits	20
SwissProt Accessions	Q01844, Q92635	Gene names	EWSR1, EWS
Domain Architecture
Description	RNA-binding protein EWS (EWS oncogene) (Ewing sarcoma breakpoint region 1 protein).

FIGN_MOUSE
θ value	4.03905 (rank : 53)	NC score	0.015271 (rank : 69)
Query Neighborhood Hits	101	Target Neighborhood Hits	165	Shared Neighborhood Hits	17
SwissProt Accessions	Q9ERZ6, Q3TPB0, Q3UP57, Q6PCM0	Gene names	Fign
Domain Architecture	No domain graphic available
Description	Fidgetin.

IASPP_MOUSE
θ value	4.03905 (rank : 54)	NC score	0.020641 (rank : 56)
Query Neighborhood Hits	101	Target Neighborhood Hits	1024	Shared Neighborhood Hits	43
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

R3HD2_MOUSE
θ value	4.03905 (rank : 55)	NC score	0.071009 (rank : 13)
Query Neighborhood Hits	101	Target Neighborhood Hits	397	Shared Neighborhood Hits	36
SwissProt Accessions	Q80TM6, Q80YB1, Q8BLS5, Q9CW50	Gene names	R3hdm2, Kiaa1002
Domain Architecture
Description	R3H domain-containing protein 2.

RGS3_HUMAN
θ value	4.03905 (rank : 56)	NC score	0.031276 (rank : 38)
Query Neighborhood Hits	101	Target Neighborhood Hits	1375	Shared Neighborhood Hits	54
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

STRC_MOUSE
θ value	4.03905 (rank : 57)	NC score	0.014093 (rank : 70)
Query Neighborhood Hits	101	Target Neighborhood Hits	89	Shared Neighborhood Hits	7
SwissProt Accessions	Q8VIM6	Gene names	Strc
Domain Architecture	No domain graphic available
Description	Stereocilin precursor.

TARA_MOUSE
θ value	4.03905 (rank : 58)	NC score	0.019275 (rank : 59)
Query Neighborhood Hits	101	Target Neighborhood Hits	1133	Shared Neighborhood Hits	31
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

ATF7_HUMAN
θ value	5.27518 (rank : 59)	NC score	0.012319 (rank : 72)
Query Neighborhood Hits	101	Target Neighborhood Hits	333	Shared Neighborhood Hits	15
SwissProt Accessions	P17544, Q13814	Gene names	ATF7, ATFA
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-7 (Activating transcription factor 7) (Transcription factor ATF-A).

CONA1_HUMAN
θ value	5.27518 (rank : 60)	NC score	0.009550 (rank : 82)
Query Neighborhood Hits	101	Target Neighborhood Hits	281	Shared Neighborhood Hits	16
SwissProt Accessions	Q86Y22, Q8IVR4, Q9NT93	Gene names	COL23A1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXIII) chain.

EWS_MOUSE
θ value	5.27518 (rank : 61)	NC score	0.030512 (rank : 39)
Query Neighborhood Hits	101	Target Neighborhood Hits	271	Shared Neighborhood Hits	20
SwissProt Accessions	Q61545	Gene names	Ewsr1, Ews, Ewsh
Domain Architecture
Description	RNA-binding protein EWS.

GP156_MOUSE
θ value	5.27518 (rank : 62)	NC score	0.025226 (rank : 47)
Query Neighborhood Hits	101	Target Neighborhood Hits	95	Shared Neighborhood Hits	8
SwissProt Accessions	Q6PCP7, Q8K452	Gene names	Gpr156, Gababl
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 156 (GABAB-related G-protein coupled receptor).

M3K11_HUMAN
θ value	5.27518 (rank : 63)	NC score	0.001385 (rank : 102)
Query Neighborhood Hits	101	Target Neighborhood Hits	1136	Shared Neighborhood Hits	27
SwissProt Accessions	Q16584, Q6P2G4	Gene names	MAP3K11, MLK3, SPRK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline- rich kinase).

PCLO_MOUSE
θ value	5.27518 (rank : 64)	NC score	0.021819 (rank : 53)
Query Neighborhood Hits	101	Target Neighborhood Hits	2275	Shared Neighborhood Hits	69
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

SIDT1_MOUSE
θ value	5.27518 (rank : 65)	NC score	0.009683 (rank : 81)
Query Neighborhood Hits	101	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q6AXF6, Q8R397	Gene names	Sidt1
Domain Architecture	No domain graphic available
Description	SID1 transmembrane family member 1 precursor.

SMCA2_HUMAN
θ value	5.27518 (rank : 66)	NC score	0.009694 (rank : 80)
Query Neighborhood Hits	101	Target Neighborhood Hits	503	Shared Neighborhood Hits	22
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

SMRC2_HUMAN
θ value	5.27518 (rank : 67)	NC score	0.022132 (rank : 52)
Query Neighborhood Hits	101	Target Neighborhood Hits	499	Shared Neighborhood Hits	22
SwissProt Accessions	Q8TAQ2, Q92923, Q96E12, Q96GY4	Gene names	SMARCC2, BAF170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

TF7L1_MOUSE
θ value	5.27518 (rank : 68)	NC score	0.007572 (rank : 90)
Query Neighborhood Hits	101	Target Neighborhood Hits	131	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Z1J1, O70450, O70573	Gene names	Tcf7l1, Tcf3
Domain Architecture
Description	Transcription factor 7-like 1 (HMG box transcription factor 3) (TCF-3) (mTCF-3).

ACK1_HUMAN
θ value	6.88961 (rank : 69)	NC score	0.001325 (rank : 103)
Query Neighborhood Hits	101	Target Neighborhood Hits	1140	Shared Neighborhood Hits	27
SwissProt Accessions	Q07912, Q8N6U7, Q96H59	Gene names	TNK2, ACK1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2).

ARHGB_HUMAN
θ value	6.88961 (rank : 70)	NC score	0.007982 (rank : 87)
Query Neighborhood Hits	101	Target Neighborhood Hits	375	Shared Neighborhood Hits	14
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

BCL9_MOUSE
θ value	6.88961 (rank : 71)	NC score	0.025845 (rank : 45)
Query Neighborhood Hits	101	Target Neighborhood Hits	770	Shared Neighborhood Hits	42
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

CO3A1_HUMAN
θ value	6.88961 (rank : 72)	NC score	0.015596 (rank : 67)
Query Neighborhood Hits	101	Target Neighborhood Hits	452	Shared Neighborhood Hits	25
SwissProt Accessions	P02461, Q15112, Q16403, Q6LDB3, Q6LDJ2, Q6LDJ3, Q7KZ56	Gene names	COL3A1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

CT194_MOUSE
θ value	6.88961 (rank : 73)	NC score	0.010449 (rank : 77)
Query Neighborhood Hits	101	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q7TT23, Q3UPD4	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf194 homolog.

DSRAD_HUMAN
θ value	6.88961 (rank : 74)	NC score	0.008179 (rank : 86)
Query Neighborhood Hits	101	Target Neighborhood Hits	58	Shared Neighborhood Hits	5
SwissProt Accessions	P55265, O15223, O43859, O43860, Q9BYM3, Q9BYM4	Gene names	ADAR, ADAR1, DSRAD, IFI4
Domain Architecture
Description	Double-stranded RNA-specific adenosine deaminase (EC 3.5.4.-) (DRADA) (136 kDa double-stranded RNA-binding protein) (P136) (K88DSRBP) (Interferon-inducible protein 4) (IFI-4 protein).

FOXD2_HUMAN
θ value	6.88961 (rank : 75)	NC score	0.002992 (rank : 98)
Query Neighborhood Hits	101	Target Neighborhood Hits	143	Shared Neighborhood Hits	8
SwissProt Accessions	O60548	Gene names	FOXD2, FKHL17, FREAC9
Domain Architecture
Description	Forkhead box protein D2 (Forkhead-related protein FKHL17) (Forkhead- related transcription factor 9) (FREAC-9).

GCX1_HUMAN
θ value	6.88961 (rank : 76)	NC score	0.019607 (rank : 57)
Query Neighborhood Hits	101	Target Neighborhood Hits	132	Shared Neighborhood Hits	14
SwissProt Accessions	Q96NM4, Q5TE33, Q5TE34, Q5TE35, Q96IC9, Q9BQN5	Gene names	GCX1, C20orf100
Domain Architecture
Description	Granulosa cell HMG box protein 1 (GCX-1).

KBTB9_HUMAN
θ value	6.88961 (rank : 77)	NC score	0.005097 (rank : 92)
Query Neighborhood Hits	101	Target Neighborhood Hits	192	Shared Neighborhood Hits	7
SwissProt Accessions	Q96CT2, Q8N388, Q96BF0, Q96PW7	Gene names	KBTBD9, KIAA1921
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 9.

LCP2_HUMAN
θ value	6.88961 (rank : 78)	NC score	0.029529 (rank : 43)
Query Neighborhood Hits	101	Target Neighborhood Hits	531	Shared Neighborhood Hits	32
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

MUC7_HUMAN
θ value	6.88961 (rank : 79)	NC score	0.043191 (rank : 26)
Query Neighborhood Hits	101	Target Neighborhood Hits	538	Shared Neighborhood Hits	34
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

OGFR_HUMAN
θ value	6.88961 (rank : 80)	NC score	0.049439 (rank : 23)
Query Neighborhood Hits	101	Target Neighborhood Hits	1582	Shared Neighborhood Hits	59
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

PC11Y_HUMAN
θ value	6.88961 (rank : 81)	NC score	0.001175 (rank : 104)
Query Neighborhood Hits	101	Target Neighborhood Hits	205	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BZA8, Q70LR6, Q70LR8, Q70LS0, Q70LS1, Q70LS2, Q70LS3, Q70LS4, Q70LS5, Q8WY34, Q9BZA9, Q9H4E1	Gene names	PCDH11Y, PCDH11, PCDH22, PCDHY
Domain Architecture	No domain graphic available
Description	Protocadherin-11 Y-linked precursor (Protocadherin-11) (Protocadherin- 22) (Protocadherin on the Y chromosome) (PCDH-Y) (Protocadherin prostate cancer) (Protocadherin-PC).

R3HD1_HUMAN
θ value	6.88961 (rank : 82)	NC score	0.033368 (rank : 35)
Query Neighborhood Hits	101	Target Neighborhood Hits	203	Shared Neighborhood Hits	17
SwissProt Accessions	Q15032, Q8IW32	Gene names	R3HDM1, KIAA0029, R3HDM
Domain Architecture	No domain graphic available
Description	R3H domain-containing protein 1.

SNPC4_HUMAN
θ value	6.88961 (rank : 83)	NC score	0.017660 (rank : 61)
Query Neighborhood Hits	101	Target Neighborhood Hits	589	Shared Neighborhood Hits	39
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

ATS2_MOUSE
θ value	8.99809 (rank : 84)	NC score	0.004452 (rank : 95)
Query Neighborhood Hits	101	Target Neighborhood Hits	179	Shared Neighborhood Hits	5
SwissProt Accessions	Q8C9W3	Gene names	Adamts2
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

ATX7_MOUSE
θ value	8.99809 (rank : 85)	NC score	0.024168 (rank : 49)
Query Neighborhood Hits	101	Target Neighborhood Hits	328	Shared Neighborhood Hits	20
SwissProt Accessions	Q8R4I1, Q8BL17	Gene names	Atxn7, Sca7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein homolog).

CK035_MOUSE
θ value	8.99809 (rank : 86)	NC score	0.010159 (rank : 78)
Query Neighborhood Hits	101	Target Neighborhood Hits	91	Shared Neighborhood Hits	4
SwissProt Accessions	Q0VET5, Q9CW10	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf35 homolog.

DGKK_HUMAN
θ value	8.99809 (rank : 87)	NC score	0.019474 (rank : 58)
Query Neighborhood Hits	101	Target Neighborhood Hits	378	Shared Neighborhood Hits	25
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

EP300_HUMAN
θ value	8.99809 (rank : 88)	NC score	0.024776 (rank : 48)
Query Neighborhood Hits	101	Target Neighborhood Hits	821	Shared Neighborhood Hits	48
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

HCN4_MOUSE
θ value	8.99809 (rank : 89)	NC score	0.007831 (rank : 89)
Query Neighborhood Hits	101	Target Neighborhood Hits	284	Shared Neighborhood Hits	18
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

HIPK3_HUMAN
θ value	8.99809 (rank : 90)	NC score	0.001677 (rank : 100)
Query Neighborhood Hits	101	Target Neighborhood Hits	867	Shared Neighborhood Hits	13
SwissProt Accessions	Q9H422, O14632, Q2PBG4, Q2PBG5, Q92632, Q9HAS2	Gene names	HIPK3, DYRK6, FIST3, PKY
Domain Architecture	No domain graphic available
Description	Homeodomain-interacting protein kinase 3 (EC 2.7.11.1) (Homolog of protein kinase YAK1) (Fas-interacting serine/threonine-protein kinase) (FIST) (Androgen receptor-interacting nuclear protein kinase) (ANPK).

HIPK3_MOUSE
θ value	8.99809 (rank : 91)	NC score	0.001474 (rank : 101)
Query Neighborhood Hits	101	Target Neighborhood Hits	857	Shared Neighborhood Hits	13
SwissProt Accessions	Q9ERH7, O88906, Q9QZR2	Gene names	Hipk3, Fist3
Domain Architecture	No domain graphic available
Description	Homeodomain-interacting protein kinase 3 (EC 2.7.11.1) (Fas- interacting serine/threonine-protein kinase) (FIST) (Nuclear body- associated kinase 3) (Nbak3) (Androgen receptor-interacting nuclear protein kinase) (ANPK).

HNF1B_MOUSE
θ value	8.99809 (rank : 92)	NC score	0.007947 (rank : 88)
Query Neighborhood Hits	101	Target Neighborhood Hits	78	Shared Neighborhood Hits	5
SwissProt Accessions	P27889, Q8R162, Q9CS26, Q9R1W1, Q9R1W2, Q9WTL5, Q9WTL6	Gene names	Tcf2, Hnf-1b, Hnf1b
Domain Architecture
Description	Hepatocyte nuclear factor 1-beta (HNF-1beta) (HNF-1B) (Variant hepatic nuclear factor 1) (VHNF1) (Homeoprotein LFB3).

KCNN3_HUMAN
θ value	8.99809 (rank : 93)	NC score	0.010887 (rank : 76)
Query Neighborhood Hits	101	Target Neighborhood Hits	216	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UGI6, O43517	Gene names	KCNN3, K3
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 3 (SK3) (SKCa3).

MK15_HUMAN
θ value	8.99809 (rank : 94)	NC score	0.000596 (rank : 105)
Query Neighborhood Hits	101	Target Neighborhood Hits	1038	Shared Neighborhood Hits	26
SwissProt Accessions	Q8TD08, Q2TCF9, Q8N362	Gene names	MAPK15, ERK8
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase 15 (EC 2.7.11.24) (Extracellular signal-regulated kinase 8).

PI5PA_HUMAN
θ value	8.99809 (rank : 95)	NC score	0.030276 (rank : 40)
Query Neighborhood Hits	101	Target Neighborhood Hits	749	Shared Neighborhood Hits	50
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

PTN23_MOUSE
θ value	8.99809 (rank : 96)	NC score	0.008242 (rank : 85)
Query Neighborhood Hits	101	Target Neighborhood Hits	726	Shared Neighborhood Hits	36
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

SETBP_HUMAN
θ value	8.99809 (rank : 97)	NC score	0.015453 (rank : 68)
Query Neighborhood Hits	101	Target Neighborhood Hits	305	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y6X0, Q9UEF3	Gene names	SETBP1, KIAA0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

SFR15_HUMAN
θ value	8.99809 (rank : 98)	NC score	0.022305 (rank : 51)
Query Neighborhood Hits	101	Target Neighborhood Hits	368	Shared Neighborhood Hits	30
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

TM108_HUMAN
θ value	8.99809 (rank : 99)	NC score	0.016595 (rank : 64)
Query Neighborhood Hits	101	Target Neighborhood Hits	166	Shared Neighborhood Hits	17
SwissProt Accessions	Q6UXF1, Q9BQH1, Q9BW81, Q9C0H3	Gene names	TMEM108, KIAA1690
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

WDR24_MOUSE
θ value	8.99809 (rank : 100)	NC score	0.003520 (rank : 97)
Query Neighborhood Hits	101	Target Neighborhood Hits	286	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CFJ9	Gene names	Wdr24
Domain Architecture	No domain graphic available
Description	WD repeat protein 24.

WNK4_HUMAN
θ value	8.99809 (rank : 101)	NC score	0.002411 (rank : 99)
Query Neighborhood Hits	101	Target Neighborhood Hits	1043	Shared Neighborhood Hits	26
SwissProt Accessions	Q96J92, Q8N8X3, Q8N8Z2, Q96DT8, Q9BYS5	Gene names	WNK4, PRKWNK4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

NBR2_HUMAN
θ value	θ > 10 (rank : 102)	NC score	0.052580 (rank : 21)
Query Neighborhood Hits	101	Target Neighborhood Hits	4	Shared Neighborhood Hits	2
SwissProt Accessions	O15453	Gene names	NBR2
Domain Architecture	No domain graphic available
Description	Protein NBR2 (Next to BRCA1 gene 2 protein).

NFKB2_MOUSE
θ value	θ > 10 (rank : 103)	NC score	0.051629 (rank : 22)
Query Neighborhood Hits	101	Target Neighborhood Hits	326	Shared Neighborhood Hits	6
SwissProt Accessions	Q9WTK5	Gene names	Nfkb2
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) [Contains: Nuclear factor NF-kappa-B p52 subunit].

TF65_HUMAN
θ value	θ > 10 (rank : 104)	NC score	0.162989 (rank : 10)
Query Neighborhood Hits	101	Target Neighborhood Hits	115	Shared Neighborhood Hits	19
SwissProt Accessions	Q04206, Q6SLK1	Gene names	RELA, NFKB3
Domain Architecture
Description	Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit).

TF65_MOUSE
θ value	θ > 10 (rank : 105)	NC score	0.149798 (rank : 11)
Query Neighborhood Hits	101	Target Neighborhood Hits	66	Shared Neighborhood Hits	9
SwissProt Accessions	Q04207, Q62025	Gene names	Rela, Nfkb3
Domain Architecture
Description	Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit).

Hits sorted by NC score

NFAC2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	101	Target Neighborhood Hits	101	Shared Neighborhood Hits	101
SwissProt Accessions	Q13469, Q13468, Q5TFW7, Q5TFW8, Q9NPX6, Q9NQH3, Q9UJR2	Gene names	NFATC2, NFAT1, NFATP
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 2 (T cell transcription factor NFAT1) (NFAT pre-existing subunit) (NF-ATp).

NFAC2_MOUSE
NC score	0.983153 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	101	Target Neighborhood Hits	98	Shared Neighborhood Hits	27
SwissProt Accessions	Q60591, Q60984, Q60985	Gene names	Nfatc2, Nfat1, Nfatp
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 2 (T cell transcription factor NFAT1) (NFAT pre-existing subunit) (NF-ATp).

NFAC1_MOUSE
NC score	0.948528 (rank : 3)	θ value	3.28708e-135 (rank : 4)
Query Neighborhood Hits	101	Target Neighborhood Hits	92	Shared Neighborhood Hits	15
SwissProt Accessions	O88942, O70345	Gene names	Nfatc1, Nfat2, Nfatc
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 1 (NFAT transcription complex cytosolic component) (NF-ATc1) (NF-ATc).

NFAC4_HUMAN
NC score	0.930044 (rank : 4)	θ value	1.0648e-109 (rank : 7)
Query Neighborhood Hits	101	Target Neighborhood Hits	165	Shared Neighborhood Hits	18
SwissProt Accessions	Q14934	Gene names	NFATC4, NFAT3
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 4 (NF-ATc4) (NFATc4) (T cell transcription factor NFAT3) (NF-AT3).

NFAC3_HUMAN
NC score	0.927376 (rank : 5)	θ value	8.41738e-115 (rank : 5)
Query Neighborhood Hits	101	Target Neighborhood Hits	102	Shared Neighborhood Hits	14
SwissProt Accessions	Q12968, O75211, Q14516, Q99840, Q99841, Q99842	Gene names	NFATC3, NFAT4
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 3 (NF-ATc3) (NFATc3) (T cell transcription factor NFAT4) (NF-AT4) (NFATx).

NFAC3_MOUSE
NC score	0.926087 (rank : 6)	θ value	2.44908e-114 (rank : 6)
Query Neighborhood Hits	101	Target Neighborhood Hits	106	Shared Neighborhood Hits	17
SwissProt Accessions	P97305, Q60896	Gene names	Nfatc3, Nfat4
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 3 (NF-ATc3) (NFATc3) (T cell transcription factor NFAT4) (NF-AT4) (NFATx).

NFAC1_HUMAN
NC score	0.922299 (rank : 7)	θ value	5.76203e-156 (rank : 3)
Query Neighborhood Hits	101	Target Neighborhood Hits	312	Shared Neighborhood Hits	33
SwissProt Accessions	O95644, Q12865, Q15793	Gene names	NFATC1, NFAT2, NFATC
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 1 (NFAT transcription complex cytosolic component) (NF-ATc1) (NF-ATc).

NFAT5_MOUSE
NC score	0.823856 (rank : 8)	θ value	1.23536e-57 (rank : 8)
Query Neighborhood Hits	101	Target Neighborhood Hits	162	Shared Neighborhood Hits	19
SwissProt Accessions	Q9WV30	Gene names	Nfat5
Domain Architecture
Description	Nuclear factor of activated T-cells 5 (T cell transcription factor NFAT5) (NF-AT5) (Rel domain-containing transcription factor NFAT5).

NFAT5_HUMAN
NC score	0.805583 (rank : 9)	θ value	1.61343e-57 (rank : 9)
Query Neighborhood Hits	101	Target Neighborhood Hits	217	Shared Neighborhood Hits	20
SwissProt Accessions	O94916, O95693, Q9UN18	Gene names	NFAT5, KIAA0827, TONEBP
Domain Architecture
Description	Nuclear factor of activated T-cells 5 (T-cell transcription factor NFAT5) (NF-AT5) (Tonicity-responsive enhancer-binding protein) (TonE- binding protein) (TonEBP).

TF65_HUMAN
NC score	0.162989 (rank : 10)	θ value	θ > 10 (rank : 104)
Query Neighborhood Hits	101	Target Neighborhood Hits	115	Shared Neighborhood Hits	19
SwissProt Accessions	Q04206, Q6SLK1	Gene names	RELA, NFKB3
Domain Architecture
Description	Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit).

TF65_MOUSE
NC score	0.149798 (rank : 11)	θ value	θ > 10 (rank : 105)
Query Neighborhood Hits	101	Target Neighborhood Hits	66	Shared Neighborhood Hits	9
SwissProt Accessions	Q04207, Q62025	Gene names	Rela, Nfkb3
Domain Architecture
Description	Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit).

AUTS2_HUMAN
NC score	0.098914 (rank : 12)	θ value	0.00665767 (rank : 10)
Query Neighborhood Hits	101	Target Neighborhood Hits	342	Shared Neighborhood Hits	26
SwissProt Accessions	Q8WXX7, Q9Y4F2	Gene names	AUTS2, KIAA0442
Domain Architecture	No domain graphic available
Description	Autism susceptibility gene 2 protein.

R3HD2_MOUSE
NC score	0.071009 (rank : 13)	θ value	4.03905 (rank : 55)
Query Neighborhood Hits	101	Target Neighborhood Hits	397	Shared Neighborhood Hits	36
SwissProt Accessions	Q80TM6, Q80YB1, Q8BLS5, Q9CW50	Gene names	R3hdm2, Kiaa1002
Domain Architecture
Description	R3H domain-containing protein 2.

PHC3_HUMAN
NC score	0.070741 (rank : 14)	θ value	0.00665767 (rank : 11)
Query Neighborhood Hits	101	Target Neighborhood Hits	218	Shared Neighborhood Hits	15
SwissProt Accessions	Q8NDX5, Q5HYF0, Q6NSG2, Q8NFT7, Q8NFZ1, Q8TBM2, Q9H971, Q9H9I4	Gene names	PHC3, EDR3, PH3
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 3 (hPH3) (Homolog of polyhomeotic 3) (Early development regulatory protein 3).

PHC3_MOUSE
NC score	0.069417 (rank : 15)	θ value	0.00869519 (rank : 12)
Query Neighborhood Hits	101	Target Neighborhood Hits	194	Shared Neighborhood Hits	14
SwissProt Accessions	Q8CHP6, Q3TLV5	Gene names	Phc3
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 3.

NCOA6_MOUSE
NC score	0.069282 (rank : 16)	θ value	0.62314 (rank : 23)
Query Neighborhood Hits	101	Target Neighborhood Hits	1076	Shared Neighborhood Hits	68
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

NCOA6_HUMAN
NC score	0.068887 (rank : 17)	θ value	0.62314 (rank : 22)
Query Neighborhood Hits	101	Target Neighborhood Hits	1202	Shared Neighborhood Hits	70
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

BSN_MOUSE
NC score	0.061564 (rank : 18)	θ value	0.47712 (rank : 21)
Query Neighborhood Hits	101	Target Neighborhood Hits	2057	Shared Neighborhood Hits	69
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

ARI1A_HUMAN
NC score	0.059626 (rank : 19)	θ value	0.47712 (rank : 20)
Query Neighborhood Hits	101	Target Neighborhood Hits	787	Shared Neighborhood Hits	41
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

MBD5_HUMAN
NC score	0.059582 (rank : 20)	θ value	1.81305 (rank : 35)
Query Neighborhood Hits	101	Target Neighborhood Hits	176	Shared Neighborhood Hits	19
SwissProt Accessions	Q9P267, Q9NUV6	Gene names	MBD5, KIAA1461
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 5 (Methyl-CpG-binding protein MBD5).

NBR2_HUMAN
NC score	0.052580 (rank : 21)	θ value	θ > 10 (rank : 102)
Query Neighborhood Hits	101	Target Neighborhood Hits	4	Shared Neighborhood Hits	2
SwissProt Accessions	O15453	Gene names	NBR2
Domain Architecture	No domain graphic available
Description	Protein NBR2 (Next to BRCA1 gene 2 protein).

NFKB2_MOUSE
NC score	0.051629 (rank : 22)	θ value	θ > 10 (rank : 103)
Query Neighborhood Hits	101	Target Neighborhood Hits	326	Shared Neighborhood Hits	6
SwissProt Accessions	Q9WTK5	Gene names	Nfkb2
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) [Contains: Nuclear factor NF-kappa-B p52 subunit].

OGFR_HUMAN
NC score	0.049439 (rank : 23)	θ value	6.88961 (rank : 80)
Query Neighborhood Hits	101	Target Neighborhood Hits	1582	Shared Neighborhood Hits	59
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

SRRM1_MOUSE
NC score	0.047793 (rank : 24)	θ value	1.38821 (rank : 31)
Query Neighborhood Hits	101	Target Neighborhood Hits	966	Shared Neighborhood Hits	47
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

RGS3_MOUSE
NC score	0.046347 (rank : 25)	θ value	0.365318 (rank : 19)
Query Neighborhood Hits	101	Target Neighborhood Hits	1621	Shared Neighborhood Hits	66
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

MUC7_HUMAN
NC score	0.043191 (rank : 26)	θ value	6.88961 (rank : 79)
Query Neighborhood Hits	101	Target Neighborhood Hits	538	Shared Neighborhood Hits	34
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

ATN1_HUMAN
NC score	0.041890 (rank : 27)	θ value	0.365318 (rank : 18)
Query Neighborhood Hits	101	Target Neighborhood Hits	676	Shared Neighborhood Hits	42
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

BCL9_HUMAN
NC score	0.040126 (rank : 28)	θ value	3.0926 (rank : 40)
Query Neighborhood Hits	101	Target Neighborhood Hits	1008	Shared Neighborhood Hits	51
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

LMBL3_MOUSE
NC score	0.039795 (rank : 29)	θ value	0.279714 (rank : 16)
Query Neighborhood Hits	101	Target Neighborhood Hits	212	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BLB7, Q641L7, Q6ZPI2, Q8C0G4	Gene names	L3mbtl3
Domain Architecture	No domain graphic available
Description	Lethal(3)malignant brain tumor-like 3 protein (L(3)mbt-like 3 protein).

ATX1_HUMAN
NC score	0.039383 (rank : 30)	θ value	0.163984 (rank : 13)
Query Neighborhood Hits	101	Target Neighborhood Hits	79	Shared Neighborhood Hits	10
SwissProt Accessions	P54253, Q9UJG2, Q9Y4J1	Gene names	ATXN1, ATX1, SCA1
Domain Architecture
Description	Ataxin-1 (Spinocerebellar ataxia type 1 protein).

LAT_MOUSE
NC score	0.038448 (rank : 31)	θ value	3.0926 (rank : 42)
Query Neighborhood Hits	101	Target Neighborhood Hits	31	Shared Neighborhood Hits	5
SwissProt Accessions	O54957	Gene names	Lat
Domain Architecture	No domain graphic available
Description	Linker for activation of T-cells family member 1 (36 kDa phospho- tyrosine adapter protein) (pp36) (p36-38).

SRRM2_MOUSE
NC score	0.038009 (rank : 32)	θ value	0.279714 (rank : 17)
Query Neighborhood Hits	101	Target Neighborhood Hits	1470	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

TSNA1_HUMAN
NC score	0.035378 (rank : 33)	θ value	1.81305 (rank : 37)
Query Neighborhood Hits	101	Target Neighborhood Hits	178	Shared Neighborhood Hits	10
SwissProt Accessions	Q96NA8	Gene names	TSNARE1
Domain Architecture	No domain graphic available
Description	t-SNARE domain-containing protein 1.

BAG3_HUMAN
NC score	0.034744 (rank : 34)	θ value	0.279714 (rank : 15)
Query Neighborhood Hits	101	Target Neighborhood Hits	314	Shared Neighborhood Hits	24
SwissProt Accessions	O95817, Q9NT20, Q9P120	Gene names	BAG3, BIS
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1).

R3HD1_HUMAN
NC score	0.033368 (rank : 35)	θ value	6.88961 (rank : 82)
Query Neighborhood Hits	101	Target Neighborhood Hits	203	Shared Neighborhood Hits	17
SwissProt Accessions	Q15032, Q8IW32	Gene names	R3HDM1, KIAA0029, R3HDM
Domain Architecture	No domain graphic available
Description	R3H domain-containing protein 1.

TR13C_HUMAN
NC score	0.031831 (rank : 36)	θ value	2.36792 (rank : 39)
Query Neighborhood Hits	101	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	Q96RJ3	Gene names	TNFRSF13C, BAFFR, BR3
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 13C (B cell- activating factor receptor) (BAFF receptor) (BAFF-R) (BLyS receptor 3) (CD268 antigen).

TARA_HUMAN
NC score	0.031701 (rank : 37)	θ value	3.0926 (rank : 46)
Query Neighborhood Hits	101	Target Neighborhood Hits	1626	Shared Neighborhood Hits	52
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

RGS3_HUMAN
NC score	0.031276 (rank : 38)	θ value	4.03905 (rank : 56)
Query Neighborhood Hits	101	Target Neighborhood Hits	1375	Shared Neighborhood Hits	54
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

EWS_MOUSE
NC score	0.030512 (rank : 39)	θ value	5.27518 (rank : 61)
Query Neighborhood Hits	101	Target Neighborhood Hits	271	Shared Neighborhood Hits	20
SwissProt Accessions	Q61545	Gene names	Ewsr1, Ews, Ewsh
Domain Architecture
Description	RNA-binding protein EWS.

PI5PA_HUMAN
NC score	0.030276 (rank : 40)	θ value	8.99809 (rank : 95)
Query Neighborhood Hits	101	Target Neighborhood Hits	749	Shared Neighborhood Hits	50
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

EWS_HUMAN
NC score	0.030174 (rank : 41)	θ value	4.03905 (rank : 52)
Query Neighborhood Hits	101	Target Neighborhood Hits	249	Shared Neighborhood Hits	20
SwissProt Accessions	Q01844, Q92635	Gene names	EWSR1, EWS
Domain Architecture
Description	RNA-binding protein EWS (EWS oncogene) (Ewing sarcoma breakpoint region 1 protein).

SI1L3_HUMAN
NC score	0.030153 (rank : 42)	θ value	3.0926 (rank : 45)
Query Neighborhood Hits	101	Target Neighborhood Hits	305	Shared Neighborhood Hits	23
SwissProt Accessions	O60292, Q2TV87	Gene names	SIPA1L3, KIAA0545, SPAL3
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 3 (SPA-1-like protein 3).

LCP2_HUMAN
NC score	0.029529 (rank : 43)	θ value	6.88961 (rank : 78)
Query Neighborhood Hits	101	Target Neighborhood Hits	531	Shared Neighborhood Hits	32
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

HGS_HUMAN
NC score	0.029353 (rank : 44)	θ value	0.813845 (rank : 24)
Query Neighborhood Hits	101	Target Neighborhood Hits	517	Shared Neighborhood Hits	24
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

BCL9_MOUSE
NC score	0.025845 (rank : 45)	θ value	6.88961 (rank : 71)
Query Neighborhood Hits	101	Target Neighborhood Hits	770	Shared Neighborhood Hits	42
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

CD008_HUMAN
NC score	0.025809 (rank : 46)	θ value	4.03905 (rank : 48)
Query Neighborhood Hits	101	Target Neighborhood Hits	330	Shared Neighborhood Hits	17
SwissProt Accessions	P78312, O43607, P78311, P78313, Q9UEG8	Gene names	C4orf8
Domain Architecture	No domain graphic available
Description	Protein C4orf8 (Protein IT14).

GP156_MOUSE
NC score	0.025226 (rank : 47)	θ value	5.27518 (rank : 62)
Query Neighborhood Hits	101	Target Neighborhood Hits	95	Shared Neighborhood Hits	8
SwissProt Accessions	Q6PCP7, Q8K452	Gene names	Gpr156, Gababl
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 156 (GABAB-related G-protein coupled receptor).

EP300_HUMAN
NC score	0.024776 (rank : 48)	θ value	8.99809 (rank : 88)
Query Neighborhood Hits	101	Target Neighborhood Hits	821	Shared Neighborhood Hits	48
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

ATX7_MOUSE
NC score	0.024168 (rank : 49)	θ value	8.99809 (rank : 85)
Query Neighborhood Hits	101	Target Neighborhood Hits	328	Shared Neighborhood Hits	20
SwissProt Accessions	Q8R4I1, Q8BL17	Gene names	Atxn7, Sca7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein homolog).

CSF1_HUMAN
NC score	0.024085 (rank : 50)	θ value	1.81305 (rank : 34)
Query Neighborhood Hits	101	Target Neighborhood Hits	258	Shared Neighborhood Hits	15
SwissProt Accessions	P09603, Q13130, Q14086, Q14806, Q9UQR8	Gene names	CSF1
Domain Architecture
Description	Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF) (M- CSF) (Lanimostim).

SFR15_HUMAN
NC score	0.022305 (rank : 51)	θ value	8.99809 (rank : 98)
Query Neighborhood Hits	101	Target Neighborhood Hits	368	Shared Neighborhood Hits	30
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

SMRC2_HUMAN
NC score	0.022132 (rank : 52)	θ value	5.27518 (rank : 67)
Query Neighborhood Hits	101	Target Neighborhood Hits	499	Shared Neighborhood Hits	22
SwissProt Accessions	Q8TAQ2, Q92923, Q96E12, Q96GY4	Gene names	SMARCC2, BAF170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

PCLO_MOUSE
NC score	0.021819 (rank : 53)	θ value	5.27518 (rank : 64)
Query Neighborhood Hits	101	Target Neighborhood Hits	2275	Shared Neighborhood Hits	69
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

RHG09_HUMAN
NC score	0.021478 (rank : 54)	θ value	1.06291 (rank : 27)
Query Neighborhood Hits	101	Target Neighborhood Hits	186	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BRR9, Q8TCJ3, Q8WYR0, Q96EZ2, Q96S74	Gene names	ARHGAP9
Domain Architecture
Description	Rho-GTPase-activating protein 9.

MINT_HUMAN
NC score	0.020770 (rank : 55)	θ value	3.0926 (rank : 43)
Query Neighborhood Hits	101	Target Neighborhood Hits	1291	Shared Neighborhood Hits	42
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

IASPP_MOUSE
NC score	0.020641 (rank : 56)	θ value	4.03905 (rank : 54)
Query Neighborhood Hits	101	Target Neighborhood Hits	1024	Shared Neighborhood Hits	43
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

GCX1_HUMAN
NC score	0.019607 (rank : 57)	θ value	6.88961 (rank : 76)
Query Neighborhood Hits	101	Target Neighborhood Hits	132	Shared Neighborhood Hits	14
SwissProt Accessions	Q96NM4, Q5TE33, Q5TE34, Q5TE35, Q96IC9, Q9BQN5	Gene names	GCX1, C20orf100
Domain Architecture
Description	Granulosa cell HMG box protein 1 (GCX-1).

DGKK_HUMAN
NC score	0.019474 (rank : 58)	θ value	8.99809 (rank : 87)
Query Neighborhood Hits	101	Target Neighborhood Hits	378	Shared Neighborhood Hits	25
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

TARA_MOUSE
NC score	0.019275 (rank : 59)	θ value	4.03905 (rank : 58)
Query Neighborhood Hits	101	Target Neighborhood Hits	1133	Shared Neighborhood Hits	31
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

FIGN_HUMAN
NC score	0.017900 (rank : 60)	θ value	1.06291 (rank : 26)
Query Neighborhood Hits	101	Target Neighborhood Hits	176	Shared Neighborhood Hits	17
SwissProt Accessions	Q5HY92, Q9H6M5, Q9NVZ9	Gene names	FIGN
Domain Architecture	No domain graphic available
Description	Fidgetin.

SNPC4_HUMAN
NC score	0.017660 (rank : 61)	θ value	6.88961 (rank : 83)
Query Neighborhood Hits	101	Target Neighborhood Hits	589	Shared Neighborhood Hits	39
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

SMAD9_HUMAN
NC score	0.016720 (rank : 62)	θ value	1.81305 (rank : 36)
Query Neighborhood Hits	101	Target Neighborhood Hits	48	Shared Neighborhood Hits	7
SwissProt Accessions	O15198, O14989	Gene names	SMAD9, MADH6, MADH9
Domain Architecture
Description	Mothers against decapentaplegic homolog 9 (SMAD 9) (Mothers against DPP homolog 9) (Smad9) (Madh6).

CO3A1_MOUSE
NC score	0.016661 (rank : 63)	θ value	1.06291 (rank : 25)
Query Neighborhood Hits	101	Target Neighborhood Hits	466	Shared Neighborhood Hits	24
SwissProt Accessions	P08121, Q61429, Q9CRN7	Gene names	Col3a1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

TM108_HUMAN
NC score	0.016595 (rank : 64)	θ value	8.99809 (rank : 99)
Query Neighborhood Hits	101	Target Neighborhood Hits	166	Shared Neighborhood Hits	17
SwissProt Accessions	Q6UXF1, Q9BQH1, Q9BW81, Q9C0H3	Gene names	TMEM108, KIAA1690
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

CASL_HUMAN
NC score	0.016333 (rank : 65)	θ value	1.81305 (rank : 32)
Query Neighborhood Hits	101	Target Neighborhood Hits	259	Shared Neighborhood Hits	13
SwissProt Accessions	Q14511	Gene names	NEDD9, CASL
Domain Architecture
Description	Enhancer of filamentation 1 (HEF1) (CRK-associated substrate-related protein) (CAS-L) (CasL) (p105) (Protein NEDD9) (NY-REN-12 antigen).

CN092_MOUSE
NC score	0.016262 (rank : 66)	θ value	3.0926 (rank : 41)
Query Neighborhood Hits	101	Target Neighborhood Hits	206	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BU11, Q80UI2, Q99PN9, Q9CS16	Gene names
Domain Architecture
Description	Epidermal Langerhans cell protein LCP1.

CO3A1_HUMAN
NC score	0.015596 (rank : 67)	θ value	6.88961 (rank : 72)
Query Neighborhood Hits	101	Target Neighborhood Hits	452	Shared Neighborhood Hits	25
SwissProt Accessions	P02461, Q15112, Q16403, Q6LDB3, Q6LDJ2, Q6LDJ3, Q7KZ56	Gene names	COL3A1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

SETBP_HUMAN
NC score	0.015453 (rank : 68)	θ value	8.99809 (rank : 97)
Query Neighborhood Hits	101	Target Neighborhood Hits	305	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y6X0, Q9UEF3	Gene names	SETBP1, KIAA0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

FIGN_MOUSE
NC score	0.015271 (rank : 69)	θ value	4.03905 (rank : 53)
Query Neighborhood Hits	101	Target Neighborhood Hits	165	Shared Neighborhood Hits	17
SwissProt Accessions	Q9ERZ6, Q3TPB0, Q3UP57, Q6PCM0	Gene names	Fign
Domain Architecture	No domain graphic available
Description	Fidgetin.

STRC_MOUSE
NC score	0.014093 (rank : 70)	θ value	4.03905 (rank : 57)
Query Neighborhood Hits	101	Target Neighborhood Hits	89	Shared Neighborhood Hits	7
SwissProt Accessions	Q8VIM6	Gene names	Strc
Domain Architecture	No domain graphic available
Description	Stereocilin precursor.

MGR1_MOUSE
NC score	0.013645 (rank : 71)	θ value	1.38821 (rank : 28)
Query Neighborhood Hits	101	Target Neighborhood Hits	90	Shared Neighborhood Hits	6
SwissProt Accessions	P97772, Q6AXG4, Q9EPV6	Gene names	Grm1, Gprc1a, Mglur1
Domain Architecture
Description	Metabotropic glutamate receptor 1 precursor (mGluR1).

ATF7_HUMAN
NC score	0.012319 (rank : 72)	θ value	5.27518 (rank : 59)
Query Neighborhood Hits	101	Target Neighborhood Hits	333	Shared Neighborhood Hits	15
SwissProt Accessions	P17544, Q13814	Gene names	ATF7, ATFA
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-7 (Activating transcription factor 7) (Transcription factor ATF-A).

AAK1_HUMAN
NC score	0.012221 (rank : 73)	θ value	4.03905 (rank : 47)
Query Neighborhood Hits	101	Target Neighborhood Hits	1077	Shared Neighborhood Hits	34
SwissProt Accessions	Q2M2I8, Q4ZFZ3, Q53RX6, Q9UPV4	Gene names	AAK1, KIAA1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

PHLB1_HUMAN
NC score	0.011393 (rank : 74)	θ value	3.0926 (rank : 44)
Query Neighborhood Hits	101	Target Neighborhood Hits	1038	Shared Neighborhood Hits	27
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

CO4A6_HUMAN
NC score	0.011217 (rank : 75)	θ value	1.81305 (rank : 33)
Query Neighborhood Hits	101	Target Neighborhood Hits	318	Shared Neighborhood Hits	17
SwissProt Accessions	Q14031, Q12823, Q14053, Q5JYH6, Q9NQM5, Q9NTX3, Q9UJ76, Q9UMG6, Q9Y4L4	Gene names	COL4A6
Domain Architecture
Description	Collagen alpha-6(IV) chain precursor.

KCNN3_HUMAN
NC score	0.010887 (rank : 76)	θ value	8.99809 (rank : 93)
Query Neighborhood Hits	101	Target Neighborhood Hits	216	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UGI6, O43517	Gene names	KCNN3, K3
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 3 (SK3) (SKCa3).

CT194_MOUSE
NC score	0.010449 (rank : 77)	θ value	6.88961 (rank : 73)
Query Neighborhood Hits	101	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q7TT23, Q3UPD4	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf194 homolog.

CK035_MOUSE
NC score	0.010159 (rank : 78)	θ value	8.99809 (rank : 86)
Query Neighborhood Hits	101	Target Neighborhood Hits	91	Shared Neighborhood Hits	4
SwissProt Accessions	Q0VET5, Q9CW10	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf35 homolog.

MAST4_HUMAN
NC score	0.009974 (rank : 79)	θ value	0.163984 (rank : 14)
Query Neighborhood Hits	101	Target Neighborhood Hits	1804	Shared Neighborhood Hits	48
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

SMCA2_HUMAN
NC score	0.009694 (rank : 80)	θ value	5.27518 (rank : 66)
Query Neighborhood Hits	101	Target Neighborhood Hits	503	Shared Neighborhood Hits	22
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

SIDT1_MOUSE
NC score	0.009683 (rank : 81)	θ value	5.27518 (rank : 65)
Query Neighborhood Hits	101	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q6AXF6, Q8R397	Gene names	Sidt1
Domain Architecture	No domain graphic available
Description	SID1 transmembrane family member 1 precursor.

CONA1_HUMAN
NC score	0.009550 (rank : 82)	θ value	5.27518 (rank : 60)
Query Neighborhood Hits	101	Target Neighborhood Hits	281	Shared Neighborhood Hits	16
SwissProt Accessions	Q86Y22, Q8IVR4, Q9NT93	Gene names	COL23A1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXIII) chain.

COE4_MOUSE
NC score	0.008786 (rank : 83)	θ value	4.03905 (rank : 49)
Query Neighborhood Hits	101	Target Neighborhood Hits	29	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K4J2, Q8K4J1, Q8K4J3, Q8K4J4, Q8K4J5	Gene names	Ebf4, Coe4
Domain Architecture
Description	Transcription factor COE4 (Early B-cell factor 4) (EBF-4) (Olf-1/EBF- like 4) (OE-4) (O/E-4).

DNMBP_MOUSE
NC score	0.008479 (rank : 84)	θ value	4.03905 (rank : 51)
Query Neighborhood Hits	101	Target Neighborhood Hits	435	Shared Neighborhood Hits	10
SwissProt Accessions	Q6TXD4, Q6ZQ05, Q8CEW8, Q8R0Y2	Gene names	Dnmbp, Kiaa1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

PTN23_MOUSE
NC score	0.008242 (rank : 85)	θ value	8.99809 (rank : 96)
Query Neighborhood Hits	101	Target Neighborhood Hits	726	Shared Neighborhood Hits	36
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

DSRAD_HUMAN
NC score	0.008179 (rank : 86)	θ value	6.88961 (rank : 74)
Query Neighborhood Hits	101	Target Neighborhood Hits	58	Shared Neighborhood Hits	5
SwissProt Accessions	P55265, O15223, O43859, O43860, Q9BYM3, Q9BYM4	Gene names	ADAR, ADAR1, DSRAD, IFI4
Domain Architecture
Description	Double-stranded RNA-specific adenosine deaminase (EC 3.5.4.-) (DRADA) (136 kDa double-stranded RNA-binding protein) (P136) (K88DSRBP) (Interferon-inducible protein 4) (IFI-4 protein).

ARHGB_HUMAN
NC score	0.007982 (rank : 87)	θ value	6.88961 (rank : 70)
Query Neighborhood Hits	101	Target Neighborhood Hits	375	Shared Neighborhood Hits	14
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

HNF1B_MOUSE
NC score	0.007947 (rank : 88)	θ value	8.99809 (rank : 92)
Query Neighborhood Hits	101	Target Neighborhood Hits	78	Shared Neighborhood Hits	5
SwissProt Accessions	P27889, Q8R162, Q9CS26, Q9R1W1, Q9R1W2, Q9WTL5, Q9WTL6	Gene names	Tcf2, Hnf-1b, Hnf1b
Domain Architecture
Description	Hepatocyte nuclear factor 1-beta (HNF-1beta) (HNF-1B) (Variant hepatic nuclear factor 1) (VHNF1) (Homeoprotein LFB3).

HCN4_MOUSE
NC score	0.007831 (rank : 89)	θ value	8.99809 (rank : 89)
Query Neighborhood Hits	101	Target Neighborhood Hits	284	Shared Neighborhood Hits	18
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

TF7L1_MOUSE
NC score	0.007572 (rank : 90)	θ value	5.27518 (rank : 68)
Query Neighborhood Hits	101	Target Neighborhood Hits	131	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Z1J1, O70450, O70573	Gene names	Tcf7l1, Tcf3
Domain Architecture
Description	Transcription factor 7-like 1 (HMG box transcription factor 3) (TCF-3) (mTCF-3).

KBTB9_MOUSE
NC score	0.006754 (rank : 91)	θ value	2.36792 (rank : 38)
Query Neighborhood Hits	101	Target Neighborhood Hits	197	Shared Neighborhood Hits	9
SwissProt Accessions	Q80T74	Gene names	Kbtbd9, Kiaa1921
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 9.

KBTB9_HUMAN
NC score	0.005097 (rank : 92)	θ value	6.88961 (rank : 77)
Query Neighborhood Hits	101	Target Neighborhood Hits	192	Shared Neighborhood Hits	7
SwissProt Accessions	Q96CT2, Q8N388, Q96BF0, Q96PW7	Gene names	KBTBD9, KIAA1921
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 9.

SP5_MOUSE
NC score	0.004661 (rank : 93)	θ value	1.38821 (rank : 30)
Query Neighborhood Hits	101	Target Neighborhood Hits	821	Shared Neighborhood Hits	17
SwissProt Accessions	Q9JHX2	Gene names	Sp5
Domain Architecture
Description	Transcription factor Sp5.

SP5_HUMAN
NC score	0.004488 (rank : 94)	θ value	1.38821 (rank : 29)
Query Neighborhood Hits	101	Target Neighborhood Hits	832	Shared Neighborhood Hits	16
SwissProt Accessions	Q6BEB4	Gene names	SP5
Domain Architecture	No domain graphic available
Description	Transcription factor Sp5.

ATS2_MOUSE
NC score	0.004452 (rank : 95)	θ value	8.99809 (rank : 84)
Query Neighborhood Hits	101	Target Neighborhood Hits	179	Shared Neighborhood Hits	5
SwissProt Accessions	Q8C9W3	Gene names	Adamts2
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

DLG5_HUMAN
NC score	0.004413 (rank : 96)	θ value	4.03905 (rank : 50)
Query Neighborhood Hits	101	Target Neighborhood Hits	1088	Shared Neighborhood Hits	15
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

WDR24_MOUSE
NC score	0.003520 (rank : 97)	θ value	8.99809 (rank : 100)
Query Neighborhood Hits	101	Target Neighborhood Hits	286	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CFJ9	Gene names	Wdr24
Domain Architecture	No domain graphic available
Description	WD repeat protein 24.

FOXD2_HUMAN
NC score	0.002992 (rank : 98)	θ value	6.88961 (rank : 75)
Query Neighborhood Hits	101	Target Neighborhood Hits	143	Shared Neighborhood Hits	8
SwissProt Accessions	O60548	Gene names	FOXD2, FKHL17, FREAC9
Domain Architecture
Description	Forkhead box protein D2 (Forkhead-related protein FKHL17) (Forkhead- related transcription factor 9) (FREAC-9).

WNK4_HUMAN
NC score	0.002411 (rank : 99)	θ value	8.99809 (rank : 101)
Query Neighborhood Hits	101	Target Neighborhood Hits	1043	Shared Neighborhood Hits	26
SwissProt Accessions	Q96J92, Q8N8X3, Q8N8Z2, Q96DT8, Q9BYS5	Gene names	WNK4, PRKWNK4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

HIPK3_HUMAN
NC score	0.001677 (rank : 100)	θ value	8.99809 (rank : 90)
Query Neighborhood Hits	101	Target Neighborhood Hits	867	Shared Neighborhood Hits	13
SwissProt Accessions	Q9H422, O14632, Q2PBG4, Q2PBG5, Q92632, Q9HAS2	Gene names	HIPK3, DYRK6, FIST3, PKY
Domain Architecture	No domain graphic available
Description	Homeodomain-interacting protein kinase 3 (EC 2.7.11.1) (Homolog of protein kinase YAK1) (Fas-interacting serine/threonine-protein kinase) (FIST) (Androgen receptor-interacting nuclear protein kinase) (ANPK).

HIPK3_MOUSE
NC score	0.001474 (rank : 101)	θ value	8.99809 (rank : 91)
Query Neighborhood Hits	101	Target Neighborhood Hits	857	Shared Neighborhood Hits	13
SwissProt Accessions	Q9ERH7, O88906, Q9QZR2	Gene names	Hipk3, Fist3
Domain Architecture	No domain graphic available
Description	Homeodomain-interacting protein kinase 3 (EC 2.7.11.1) (Fas- interacting serine/threonine-protein kinase) (FIST) (Nuclear body- associated kinase 3) (Nbak3) (Androgen receptor-interacting nuclear protein kinase) (ANPK).

M3K11_HUMAN
NC score	0.001385 (rank : 102)	θ value	5.27518 (rank : 63)
Query Neighborhood Hits	101	Target Neighborhood Hits	1136	Shared Neighborhood Hits	27
SwissProt Accessions	Q16584, Q6P2G4	Gene names	MAP3K11, MLK3, SPRK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline- rich kinase).

ACK1_HUMAN
NC score	0.001325 (rank : 103)	θ value	6.88961 (rank : 69)
Query Neighborhood Hits	101	Target Neighborhood Hits	1140	Shared Neighborhood Hits	27
SwissProt Accessions	Q07912, Q8N6U7, Q96H59	Gene names	TNK2, ACK1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2).

PC11Y_HUMAN
NC score	0.001175 (rank : 104)	θ value	6.88961 (rank : 81)
Query Neighborhood Hits	101	Target Neighborhood Hits	205	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BZA8, Q70LR6, Q70LR8, Q70LS0, Q70LS1, Q70LS2, Q70LS3, Q70LS4, Q70LS5, Q8WY34, Q9BZA9, Q9H4E1	Gene names	PCDH11Y, PCDH11, PCDH22, PCDHY
Domain Architecture	No domain graphic available
Description	Protocadherin-11 Y-linked precursor (Protocadherin-11) (Protocadherin- 22) (Protocadherin on the Y chromosome) (PCDH-Y) (Protocadherin prostate cancer) (Protocadherin-PC).

MK15_HUMAN
NC score	0.000596 (rank : 105)	θ value	8.99809 (rank : 94)
Query Neighborhood Hits	101	Target Neighborhood Hits	1038	Shared Neighborhood Hits	26
SwissProt Accessions	Q8TD08, Q2TCF9, Q8N362	Gene names	MAPK15, ERK8
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase 15 (EC 2.7.11.24) (Extracellular signal-regulated kinase 8).