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Network neighborhood for query Sequence : GRIK1_MOUSE

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GRIK1_MOUSE
SwissProt Accessions	Q60934	Gene names	Grik1, Glur5
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 1 precursor (Glutamate receptor 5) (GluR-5) (GluR5).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

GRIK1_HUMAN
θ value	0 (rank : 1)	NC score	0.998658 (rank : 2)
Query Neighborhood Hits	46	Target Neighborhood Hits	48	Shared Neighborhood Hits	44
SwissProt Accessions	P39086, Q13001, Q86SU9	Gene names	GRIK1, GLUR5
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 1 precursor (Glutamate receptor 5) (GluR-5) (GluR5) (Excitatory amino acid receptor 3) (EAA3).

GRIK1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	46	Target Neighborhood Hits	46	Shared Neighborhood Hits	46
SwissProt Accessions	Q60934	Gene names	Grik1, Glur5
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 1 precursor (Glutamate receptor 5) (GluR-5) (GluR5).

GRIK2_HUMAN
θ value	0 (rank : 3)	NC score	0.997648 (rank : 3)
Query Neighborhood Hits	46	Target Neighborhood Hits	50	Shared Neighborhood Hits	41
SwissProt Accessions	Q13002	Gene names	GRIK2, GLUR6
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 2 precursor (Glutamate receptor 6) (GluR-6) (GluR6) (Excitatory amino acid receptor 4) (EAA4).

GRIK3_HUMAN
θ value	0 (rank : 4)	NC score	0.996823 (rank : 4)
Query Neighborhood Hits	46	Target Neighborhood Hits	41	Shared Neighborhood Hits	39
SwissProt Accessions	Q13003, Q13004, Q16136	Gene names	GRIK3, GLUR7
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 3 precursor (Glutamate receptor 7) (GluR-7) (GluR7) (Excitatory amino acid receptor 5) (EAA5).

GRIK5_MOUSE
θ value	1.08919e-146 (rank : 5)	NC score	0.982103 (rank : 6)
Query Neighborhood Hits	46	Target Neighborhood Hits	47	Shared Neighborhood Hits	33
SwissProt Accessions	Q61626	Gene names	Grik5
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 5 precursor (Glutamate receptor KA-2) (KA2) (Glutamate receptor gamma-2) (GluR gamma-2).

GRIK5_HUMAN
θ value	9.22056e-146 (rank : 6)	NC score	0.982123 (rank : 5)
Query Neighborhood Hits	46	Target Neighborhood Hits	44	Shared Neighborhood Hits	33
SwissProt Accessions	Q16478	Gene names	GRIK5, GRIK2
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 5 precursor (Glutamate receptor KA-2) (KA2) (Excitatory amino acid receptor 2) (EAA2).

GRIK4_MOUSE
θ value	1.37783e-141 (rank : 7)	NC score	0.981127 (rank : 8)
Query Neighborhood Hits	46	Target Neighborhood Hits	41	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BMF5	Gene names	Grik4
Domain Architecture	No domain graphic available
Description	Glutamate receptor, ionotropic kainate 4 precursor.

GRIK4_HUMAN
θ value	5.78879e-140 (rank : 8)	NC score	0.981144 (rank : 7)
Query Neighborhood Hits	46	Target Neighborhood Hits	42	Shared Neighborhood Hits	33
SwissProt Accessions	Q16099	Gene names	GRIK4, GRIK
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 4 precursor (Glutamate receptor KA-1) (KA1) (Excitatory amino acid receptor 1) (EAA1).

GRIA1_MOUSE
θ value	1.09172e-138 (rank : 9)	NC score	0.977296 (rank : 9)
Query Neighborhood Hits	46	Target Neighborhood Hits	46	Shared Neighborhood Hits	34
SwissProt Accessions	P23818	Gene names	Gria1, Glur1
Domain Architecture
Description	Glutamate receptor 1 precursor (GluR-1) (GluR-A) (GluR-K1) (Glutamate receptor ionotropic, AMPA 1) (AMPA-selective glutamate receptor 1).

GRIA1_HUMAN
θ value	2.4321e-138 (rank : 10)	NC score	0.977158 (rank : 10)
Query Neighborhood Hits	46	Target Neighborhood Hits	45	Shared Neighborhood Hits	33
SwissProt Accessions	P42261	Gene names	GRIA1, GLUH1, GLUR1
Domain Architecture
Description	Glutamate receptor 1 precursor (GluR-1) (GluR-A) (GluR-K1) (Glutamate receptor ionotropic, AMPA 1) (AMPA-selective glutamate receptor 1).

GRIA3_MOUSE
θ value	7.07634e-138 (rank : 11)	NC score	0.976690 (rank : 12)
Query Neighborhood Hits	46	Target Neighborhood Hits	39	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Z2W9, Q5DTJ0	Gene names	Gria3, Glur3, Kiaa4184
Domain Architecture	No domain graphic available
Description	Glutamate receptor 3 precursor (GluR-3) (GluR-C) (GluR-K3) (Glutamate receptor ionotropic, AMPA 3) (AMPA-selective glutamate receptor 3).

GRIA3_HUMAN
θ value	4.58675e-137 (rank : 12)	NC score	0.976908 (rank : 11)
Query Neighborhood Hits	46	Target Neighborhood Hits	40	Shared Neighborhood Hits	33
SwissProt Accessions	P42263, Q4VXD5, Q4VXD6, Q9HDA0, Q9HDA1, Q9HDA2	Gene names	GRIA3, GLUR3, GLURC
Domain Architecture
Description	Glutamate receptor 3 precursor (GluR-3) (GluR-C) (GluR-K3) (Glutamate receptor ionotropic, AMPA 3) (AMPA-selective glutamate receptor 3).

GRIA4_HUMAN
θ value	1.24909e-134 (rank : 13)	NC score	0.975620 (rank : 15)
Query Neighborhood Hits	46	Target Neighborhood Hits	45	Shared Neighborhood Hits	34
SwissProt Accessions	P48058	Gene names	GRIA4, GLUR4
Domain Architecture
Description	Glutamate receptor 4 precursor (GluR-4) (GluR4) (GluR-D) (Glutamate receptor ionotropic, AMPA 4) (AMPA-selective glutamate receptor 4).

GRIA2_MOUSE
θ value	8.09639e-134 (rank : 14)	NC score	0.975763 (rank : 14)
Query Neighborhood Hits	46	Target Neighborhood Hits	47	Shared Neighborhood Hits	33
SwissProt Accessions	P23819, Q61604, Q61605, Q8BG69, Q8BXU3, Q9D6D3	Gene names	Gria2, Glur2
Domain Architecture
Description	Glutamate receptor 2 precursor (GluR-2) (GluR-B) (GluR-K2) (Glutamate receptor ionotropic, AMPA 2) (AMPA-selective glutamate receptor 2).

GRIA2_HUMAN
θ value	1.38103e-133 (rank : 15)	NC score	0.975845 (rank : 13)
Query Neighborhood Hits	46	Target Neighborhood Hits	47	Shared Neighborhood Hits	33
SwissProt Accessions	P42262, Q96FP6	Gene names	GRIA2, GLUR2
Domain Architecture
Description	Glutamate receptor 2 precursor (GluR-2) (GluR-B) (GluR-K2) (Glutamate receptor ionotropic, AMPA 2) (AMPA-selective glutamate receptor 2).

GRIA4_MOUSE
θ value	2.35568e-133 (rank : 16)	NC score	0.975609 (rank : 16)
Query Neighborhood Hits	46	Target Neighborhood Hits	44	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Z2W8	Gene names	Gria4, Glur4
Domain Architecture
Description	Glutamate receptor 4 precursor (GluR-4) (GluR4) (GluR-D) (Glutamate receptor ionotropic, AMPA 4) (AMPA-selective glutamate receptor 4).

GRID1_MOUSE
θ value	2.1655e-78 (rank : 17)	NC score	0.946155 (rank : 18)
Query Neighborhood Hits	46	Target Neighborhood Hits	42	Shared Neighborhood Hits	33
SwissProt Accessions	Q61627	Gene names	Grid1
Domain Architecture
Description	Glutamate receptor delta-1 subunit precursor (GluR delta-1).

GRID1_HUMAN
θ value	6.30065e-78 (rank : 18)	NC score	0.946175 (rank : 17)
Query Neighborhood Hits	46	Target Neighborhood Hits	42	Shared Neighborhood Hits	33
SwissProt Accessions	Q9ULK0, Q8IXT3	Gene names	GRID1, KIAA1220
Domain Architecture
Description	Glutamate receptor delta-1 subunit precursor (GluR delta-1).

GRID2_MOUSE
θ value	3.02872e-72 (rank : 19)	NC score	0.945148 (rank : 19)
Query Neighborhood Hits	46	Target Neighborhood Hits	44	Shared Neighborhood Hits	34
SwissProt Accessions	Q61625	Gene names	Grid2
Domain Architecture
Description	Glutamate receptor delta-2 subunit precursor (GluR delta-2).

GRID2_HUMAN
θ value	1.15091e-71 (rank : 20)	NC score	0.944940 (rank : 20)
Query Neighborhood Hits	46	Target Neighborhood Hits	48	Shared Neighborhood Hits	34
SwissProt Accessions	O43424	Gene names	GRID2, GLURD2
Domain Architecture
Description	Glutamate receptor delta-2 subunit precursor (GluR delta-2).

NMDZ1_MOUSE
θ value	1.56274e-52 (rank : 21)	NC score	0.903467 (rank : 21)
Query Neighborhood Hits	46	Target Neighborhood Hits	76	Shared Neighborhood Hits	43
SwissProt Accessions	P35438, Q8CFS4	Gene names	Grin1, Glurz1
Domain Architecture
Description	Glutamate [NMDA] receptor subunit zeta 1 precursor (N-methyl-D- aspartate receptor subunit NR1).

NMDZ1_HUMAN
θ value	4.54686e-52 (rank : 22)	NC score	0.903162 (rank : 22)
Query Neighborhood Hits	46	Target Neighborhood Hits	77	Shared Neighborhood Hits	43
SwissProt Accessions	Q05586, P35437, Q12867, Q12868	Gene names	GRIN1, NMDAR1
Domain Architecture
Description	Glutamate [NMDA] receptor subunit zeta 1 precursor (N-methyl-D- aspartate receptor subunit NR1).

NMDE2_HUMAN
θ value	1.12514e-34 (rank : 23)	NC score	0.822514 (rank : 30)
Query Neighborhood Hits	46	Target Neighborhood Hits	65	Shared Neighborhood Hits	36
SwissProt Accessions	Q13224, Q12919, Q13220, Q13225, Q9UM56	Gene names	GRIN2B
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 2 precursor (N-methyl D- aspartate receptor subtype 2B) (NR2B) (NMDAR2B) (N-methyl-D-aspartate receptor subunit 3) (NR3) (hNR3).

NMDE2_MOUSE
θ value	1.12514e-34 (rank : 24)	NC score	0.822517 (rank : 29)
Query Neighborhood Hits	46	Target Neighborhood Hits	64	Shared Neighborhood Hits	36
SwissProt Accessions	Q01097, Q9DCB2	Gene names	Grin2b
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 2 precursor (N-methyl D- aspartate receptor subtype 2B) (NR2B) (NMDAR2B).

NMDE4_HUMAN
θ value	1.12514e-34 (rank : 25)	NC score	0.828064 (rank : 26)
Query Neighborhood Hits	46	Target Neighborhood Hits	133	Shared Neighborhood Hits	34
SwissProt Accessions	O15399	Gene names	GRIN2D
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 4 precursor (N-methyl D- aspartate receptor subtype 2D) (NR2D) (NMDAR2D) (EB11).

NMDE4_MOUSE
θ value	1.12514e-34 (rank : 26)	NC score	0.825882 (rank : 27)
Query Neighborhood Hits	46	Target Neighborhood Hits	158	Shared Neighborhood Hits	34
SwissProt Accessions	Q03391	Gene names	Grin2d
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 4 precursor (N-methyl D- aspartate receptor subtype 2D) (NR2D) (NMDAR2D).

NMDE1_HUMAN
θ value	1.37539e-32 (rank : 27)	NC score	0.818234 (rank : 33)
Query Neighborhood Hits	46	Target Neighborhood Hits	81	Shared Neighborhood Hits	33
SwissProt Accessions	Q12879, O00669	Gene names	GRIN2A
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 1 precursor (N-methyl D- aspartate receptor subtype 2A) (NR2A) (NMDAR2A) (hNR2A).

NMDE1_MOUSE
θ value	1.37539e-32 (rank : 28)	NC score	0.818341 (rank : 32)
Query Neighborhood Hits	46	Target Neighborhood Hits	84	Shared Neighborhood Hits	34
SwissProt Accessions	P35436	Gene names	Grin2a
Domain Architecture	No domain graphic available
Description	Glutamate [NMDA] receptor subunit epsilon 1 precursor (N-methyl D- aspartate receptor subtype 2A) (NR2A) (NMDAR2A).

NMDE3_MOUSE
θ value	2.34606e-32 (rank : 29)	NC score	0.823029 (rank : 28)
Query Neighborhood Hits	46	Target Neighborhood Hits	86	Shared Neighborhood Hits	34
SwissProt Accessions	Q01098	Gene names	Grin2c
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 3 precursor (N-methyl D- aspartate receptor subtype 2C) (NR2C) (NMDAR2C).

NMDE3_HUMAN
θ value	8.91499e-32 (rank : 30)	NC score	0.821361 (rank : 31)
Query Neighborhood Hits	46	Target Neighborhood Hits	110	Shared Neighborhood Hits	34
SwissProt Accessions	Q14957	Gene names	GRIN2C
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 3 precursor (N-methyl D- aspartate receptor subtype 2C) (NR2C) (NMDAR2C).

NMD3B_HUMAN
θ value	4.28545e-26 (rank : 31)	NC score	0.845906 (rank : 24)
Query Neighborhood Hits	46	Target Neighborhood Hits	55	Shared Neighborhood Hits	35
SwissProt Accessions	O60391, Q5EAK7, Q7RTW9	Gene names	GRIN3B
Domain Architecture	No domain graphic available
Description	Glutamate [NMDA] receptor subunit 3B precursor (N-methyl-D-aspartate receptor subtype NR3B) (NR3B) (NMDAR3B).

NMD3B_MOUSE
θ value	2.77775e-25 (rank : 32)	NC score	0.843574 (rank : 25)
Query Neighborhood Hits	46	Target Neighborhood Hits	51	Shared Neighborhood Hits	33
SwissProt Accessions	Q91ZU9, Q8VHV0	Gene names	Grin3b
Domain Architecture	No domain graphic available
Description	Glutamate [NMDA] receptor subunit 3B precursor (N-methyl-D-aspartate receptor subunit NR3B) (NR3B) (NMDAR3B) (NMDA receptor NR4) (Nr4).

NMD3A_HUMAN
θ value	3.07116e-24 (rank : 33)	NC score	0.849246 (rank : 23)
Query Neighborhood Hits	46	Target Neighborhood Hits	58	Shared Neighborhood Hits	35
SwissProt Accessions	Q8TCU5, Q8TF29, Q8WXI6	Gene names	GRIN3A, KIAA1973
Domain Architecture	No domain graphic available
Description	Glutamate [NMDA] receptor subunit 3A precursor (N-methyl-D-aspartate receptor subtype NR3A) (NMDAR-L).

MGR1_HUMAN
θ value	0.00228821 (rank : 34)	NC score	0.068881 (rank : 41)
Query Neighborhood Hits	46	Target Neighborhood Hits	85	Shared Neighborhood Hits	20
SwissProt Accessions	Q13255, Q13256, Q14757, Q14758, Q5VTF7, Q5VTF8, Q9NU10, Q9UGS9, Q9UGT0	Gene names	GRM1, GPRC1A, MGLUR1
Domain Architecture
Description	Metabotropic glutamate receptor 1 precursor (mGluR1).

MGR1_MOUSE
θ value	0.00228821 (rank : 35)	NC score	0.068897 (rank : 40)
Query Neighborhood Hits	46	Target Neighborhood Hits	90	Shared Neighborhood Hits	20
SwissProt Accessions	P97772, Q6AXG4, Q9EPV6	Gene names	Grm1, Gprc1a, Mglur1
Domain Architecture
Description	Metabotropic glutamate receptor 1 precursor (mGluR1).

MGR5_HUMAN
θ value	0.00390308 (rank : 36)	NC score	0.070171 (rank : 37)
Query Neighborhood Hits	46	Target Neighborhood Hits	72	Shared Neighborhood Hits	20
SwissProt Accessions	P41594	Gene names	GRM5, GPRC1E, MGLUR5
Domain Architecture
Description	Metabotropic glutamate receptor 5 precursor (mGluR5).

CASR_HUMAN
θ value	0.00665767 (rank : 37)	NC score	0.074461 (rank : 35)
Query Neighborhood Hits	46	Target Neighborhood Hits	71	Shared Neighborhood Hits	13
SwissProt Accessions	P41180, Q13912, Q16108, Q16109, Q16110, Q16379, Q4PJ19	Gene names	CASR, GPRC2A, PCAR1
Domain Architecture
Description	Extracellular calcium-sensing receptor precursor (CaSR) (Parathyroid Cell calcium-sensing receptor).

CASR_MOUSE
θ value	0.00665767 (rank : 38)	NC score	0.074428 (rank : 36)
Query Neighborhood Hits	46	Target Neighborhood Hits	72	Shared Neighborhood Hits	13
SwissProt Accessions	Q9QY96, O08968, O88519, Q9QY95, Q9QZU8, Q9R1D6, Q9R1Y2	Gene names	Casr, Gprc2a
Domain Architecture
Description	Extracellular calcium-sensing receptor precursor (CaSR) (Parathyroid Cell calcium-sensing receptor).

TS1R2_HUMAN
θ value	0.0431538 (rank : 39)	NC score	0.064529 (rank : 43)
Query Neighborhood Hits	46	Target Neighborhood Hits	48	Shared Neighborhood Hits	15
SwissProt Accessions	Q8TE23, Q5TZ19	Gene names	TAS1R2, GPR71, T1R2, TR2
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 2 precursor (G-protein coupled receptor 71) (Sweet taste receptor T1R2).

TS1R2_MOUSE
θ value	0.0563607 (rank : 40)	NC score	0.075841 (rank : 34)
Query Neighborhood Hits	46	Target Neighborhood Hits	69	Shared Neighborhood Hits	18
SwissProt Accessions	Q925I4, Q923J8	Gene names	Tas1r2, Gpr71, T1r2, Tr2
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 2 precursor (G-protein coupled receptor 71) (Sweet taste receptor T1R2).

ANPRC_MOUSE
θ value	3.0926 (rank : 41)	NC score	0.037689 (rank : 45)
Query Neighborhood Hits	46	Target Neighborhood Hits	27	Shared Neighborhood Hits	10
SwissProt Accessions	P70180, P97804, Q9R025, Q9R027, Q9R028	Gene names	Npr3
Domain Architecture
Description	Atrial natriuretic peptide clearance receptor precursor (ANP-C) (ANPRC) (NPR-C) (Atrial natriuretic peptide C-type receptor) (EF-2).

ANPRC_HUMAN
θ value	6.88961 (rank : 42)	NC score	0.037372 (rank : 46)
Query Neighborhood Hits	46	Target Neighborhood Hits	27	Shared Neighborhood Hits	10
SwissProt Accessions	P17342	Gene names	NPR3, ANPRC
Domain Architecture
Description	Atrial natriuretic peptide clearance receptor precursor (ANP-C) (ANPRC) (NPR-C) (Atrial natriuretic peptide C-type receptor).

FBXW5_MOUSE
θ value	6.88961 (rank : 43)	NC score	0.004487 (rank : 48)
Query Neighborhood Hits	46	Target Neighborhood Hits	159	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QXW2	Gene names	Fbxw5, Fbw5
Domain Architecture
Description	F-box/WD repeat protein 5 (F-box and WD-40 domain protein 5).

TS1R1_MOUSE
θ value	6.88961 (rank : 44)	NC score	0.067039 (rank : 42)
Query Neighborhood Hits	46	Target Neighborhood Hits	57	Shared Neighborhood Hits	19
SwissProt Accessions	Q99PG6, Q6NS58, Q923J9, Q925I5, Q99PG5	Gene names	Tas1r1, Gpr70, T1r1, Tr1
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 1 precursor (G-protein coupled receptor 70).

DCAK2_HUMAN
θ value	8.99809 (rank : 45)	NC score	-0.004944 (rank : 49)
Query Neighborhood Hits	46	Target Neighborhood Hits	862	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N568, Q8N399	Gene names	DCAMKL2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase DCAMKL2 (EC 2.7.11.1) (Doublecortin- like and CAM kinase-like 2).

TOPB1_MOUSE
θ value	8.99809 (rank : 46)	NC score	0.006395 (rank : 47)
Query Neighborhood Hits	46	Target Neighborhood Hits	89	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZQF0, Q6P6P0, Q80Y33, Q8BUI0, Q8BUK1, Q8R348, Q91VX3, Q922X8	Gene names	Topbp1, Kiaa0259
Domain Architecture	No domain graphic available
Description	DNA topoisomerase II-binding protein 1 (DNA topoisomerase IIbeta- binding protein 1) (TopBP1).

ERB1_HUMAN
θ value	θ > 10 (rank : 47)	NC score	0.051029 (rank : 44)
Query Neighborhood Hits	46	Target Neighborhood Hits	23	Shared Neighborhood Hits	8
SwissProt Accessions	P60509	Gene names
Domain Architecture	No domain graphic available
Description	HERV-R(b)_3p24.3 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (HERV-R(b) Env protein) [Includes: Surface protein domain (SU); Transmembrane protein domain (TM)].

GABR1_HUMAN
θ value	θ > 10 (rank : 48)	NC score	0.069648 (rank : 38)
Query Neighborhood Hits	46	Target Neighborhood Hits	142	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UBS5, O95375, O95468, O95975, O96022, Q86W60, Q9UQQ0	Gene names	GABBR1, GPRC3A
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 1 precursor (GABA-B receptor 1) (GABA-B-R1) (Gb1).

GABR1_MOUSE
θ value	θ > 10 (rank : 49)	NC score	0.069528 (rank : 39)
Query Neighborhood Hits	46	Target Neighborhood Hits	139	Shared Neighborhood Hits	23
SwissProt Accessions	Q9WV18, Q9WU48, Q9WV15, Q9WV16, Q9WV17	Gene names	Gabbr1
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 1 precursor (GABA-B receptor 1) (GABA-B-R1) (Gb1).

Hits sorted by NC score

GRIK1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	46	Target Neighborhood Hits	46	Shared Neighborhood Hits	46
SwissProt Accessions	Q60934	Gene names	Grik1, Glur5
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 1 precursor (Glutamate receptor 5) (GluR-5) (GluR5).

GRIK1_HUMAN
NC score	0.998658 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	46	Target Neighborhood Hits	48	Shared Neighborhood Hits	44
SwissProt Accessions	P39086, Q13001, Q86SU9	Gene names	GRIK1, GLUR5
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 1 precursor (Glutamate receptor 5) (GluR-5) (GluR5) (Excitatory amino acid receptor 3) (EAA3).

GRIK2_HUMAN
NC score	0.997648 (rank : 3)	θ value	0 (rank : 3)
Query Neighborhood Hits	46	Target Neighborhood Hits	50	Shared Neighborhood Hits	41
SwissProt Accessions	Q13002	Gene names	GRIK2, GLUR6
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 2 precursor (Glutamate receptor 6) (GluR-6) (GluR6) (Excitatory amino acid receptor 4) (EAA4).

GRIK3_HUMAN
NC score	0.996823 (rank : 4)	θ value	0 (rank : 4)
Query Neighborhood Hits	46	Target Neighborhood Hits	41	Shared Neighborhood Hits	39
SwissProt Accessions	Q13003, Q13004, Q16136	Gene names	GRIK3, GLUR7
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 3 precursor (Glutamate receptor 7) (GluR-7) (GluR7) (Excitatory amino acid receptor 5) (EAA5).

GRIK5_HUMAN
NC score	0.982123 (rank : 5)	θ value	9.22056e-146 (rank : 6)
Query Neighborhood Hits	46	Target Neighborhood Hits	44	Shared Neighborhood Hits	33
SwissProt Accessions	Q16478	Gene names	GRIK5, GRIK2
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 5 precursor (Glutamate receptor KA-2) (KA2) (Excitatory amino acid receptor 2) (EAA2).

GRIK5_MOUSE
NC score	0.982103 (rank : 6)	θ value	1.08919e-146 (rank : 5)
Query Neighborhood Hits	46	Target Neighborhood Hits	47	Shared Neighborhood Hits	33
SwissProt Accessions	Q61626	Gene names	Grik5
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 5 precursor (Glutamate receptor KA-2) (KA2) (Glutamate receptor gamma-2) (GluR gamma-2).

GRIK4_HUMAN
NC score	0.981144 (rank : 7)	θ value	5.78879e-140 (rank : 8)
Query Neighborhood Hits	46	Target Neighborhood Hits	42	Shared Neighborhood Hits	33
SwissProt Accessions	Q16099	Gene names	GRIK4, GRIK
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 4 precursor (Glutamate receptor KA-1) (KA1) (Excitatory amino acid receptor 1) (EAA1).

GRIK4_MOUSE
NC score	0.981127 (rank : 8)	θ value	1.37783e-141 (rank : 7)
Query Neighborhood Hits	46	Target Neighborhood Hits	41	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BMF5	Gene names	Grik4
Domain Architecture	No domain graphic available
Description	Glutamate receptor, ionotropic kainate 4 precursor.

GRIA1_MOUSE
NC score	0.977296 (rank : 9)	θ value	1.09172e-138 (rank : 9)
Query Neighborhood Hits	46	Target Neighborhood Hits	46	Shared Neighborhood Hits	34
SwissProt Accessions	P23818	Gene names	Gria1, Glur1
Domain Architecture
Description	Glutamate receptor 1 precursor (GluR-1) (GluR-A) (GluR-K1) (Glutamate receptor ionotropic, AMPA 1) (AMPA-selective glutamate receptor 1).

GRIA1_HUMAN
NC score	0.977158 (rank : 10)	θ value	2.4321e-138 (rank : 10)
Query Neighborhood Hits	46	Target Neighborhood Hits	45	Shared Neighborhood Hits	33
SwissProt Accessions	P42261	Gene names	GRIA1, GLUH1, GLUR1
Domain Architecture
Description	Glutamate receptor 1 precursor (GluR-1) (GluR-A) (GluR-K1) (Glutamate receptor ionotropic, AMPA 1) (AMPA-selective glutamate receptor 1).

GRIA3_HUMAN
NC score	0.976908 (rank : 11)	θ value	4.58675e-137 (rank : 12)
Query Neighborhood Hits	46	Target Neighborhood Hits	40	Shared Neighborhood Hits	33
SwissProt Accessions	P42263, Q4VXD5, Q4VXD6, Q9HDA0, Q9HDA1, Q9HDA2	Gene names	GRIA3, GLUR3, GLURC
Domain Architecture
Description	Glutamate receptor 3 precursor (GluR-3) (GluR-C) (GluR-K3) (Glutamate receptor ionotropic, AMPA 3) (AMPA-selective glutamate receptor 3).

GRIA3_MOUSE
NC score	0.976690 (rank : 12)	θ value	7.07634e-138 (rank : 11)
Query Neighborhood Hits	46	Target Neighborhood Hits	39	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Z2W9, Q5DTJ0	Gene names	Gria3, Glur3, Kiaa4184
Domain Architecture	No domain graphic available
Description	Glutamate receptor 3 precursor (GluR-3) (GluR-C) (GluR-K3) (Glutamate receptor ionotropic, AMPA 3) (AMPA-selective glutamate receptor 3).

GRIA2_HUMAN
NC score	0.975845 (rank : 13)	θ value	1.38103e-133 (rank : 15)
Query Neighborhood Hits	46	Target Neighborhood Hits	47	Shared Neighborhood Hits	33
SwissProt Accessions	P42262, Q96FP6	Gene names	GRIA2, GLUR2
Domain Architecture
Description	Glutamate receptor 2 precursor (GluR-2) (GluR-B) (GluR-K2) (Glutamate receptor ionotropic, AMPA 2) (AMPA-selective glutamate receptor 2).

GRIA2_MOUSE
NC score	0.975763 (rank : 14)	θ value	8.09639e-134 (rank : 14)
Query Neighborhood Hits	46	Target Neighborhood Hits	47	Shared Neighborhood Hits	33
SwissProt Accessions	P23819, Q61604, Q61605, Q8BG69, Q8BXU3, Q9D6D3	Gene names	Gria2, Glur2
Domain Architecture
Description	Glutamate receptor 2 precursor (GluR-2) (GluR-B) (GluR-K2) (Glutamate receptor ionotropic, AMPA 2) (AMPA-selective glutamate receptor 2).

GRIA4_HUMAN
NC score	0.975620 (rank : 15)	θ value	1.24909e-134 (rank : 13)
Query Neighborhood Hits	46	Target Neighborhood Hits	45	Shared Neighborhood Hits	34
SwissProt Accessions	P48058	Gene names	GRIA4, GLUR4
Domain Architecture
Description	Glutamate receptor 4 precursor (GluR-4) (GluR4) (GluR-D) (Glutamate receptor ionotropic, AMPA 4) (AMPA-selective glutamate receptor 4).

GRIA4_MOUSE
NC score	0.975609 (rank : 16)	θ value	2.35568e-133 (rank : 16)
Query Neighborhood Hits	46	Target Neighborhood Hits	44	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Z2W8	Gene names	Gria4, Glur4
Domain Architecture
Description	Glutamate receptor 4 precursor (GluR-4) (GluR4) (GluR-D) (Glutamate receptor ionotropic, AMPA 4) (AMPA-selective glutamate receptor 4).

GRID1_HUMAN
NC score	0.946175 (rank : 17)	θ value	6.30065e-78 (rank : 18)
Query Neighborhood Hits	46	Target Neighborhood Hits	42	Shared Neighborhood Hits	33
SwissProt Accessions	Q9ULK0, Q8IXT3	Gene names	GRID1, KIAA1220
Domain Architecture
Description	Glutamate receptor delta-1 subunit precursor (GluR delta-1).

GRID1_MOUSE
NC score	0.946155 (rank : 18)	θ value	2.1655e-78 (rank : 17)
Query Neighborhood Hits	46	Target Neighborhood Hits	42	Shared Neighborhood Hits	33
SwissProt Accessions	Q61627	Gene names	Grid1
Domain Architecture
Description	Glutamate receptor delta-1 subunit precursor (GluR delta-1).

GRID2_MOUSE
NC score	0.945148 (rank : 19)	θ value	3.02872e-72 (rank : 19)
Query Neighborhood Hits	46	Target Neighborhood Hits	44	Shared Neighborhood Hits	34
SwissProt Accessions	Q61625	Gene names	Grid2
Domain Architecture
Description	Glutamate receptor delta-2 subunit precursor (GluR delta-2).

GRID2_HUMAN
NC score	0.944940 (rank : 20)	θ value	1.15091e-71 (rank : 20)
Query Neighborhood Hits	46	Target Neighborhood Hits	48	Shared Neighborhood Hits	34
SwissProt Accessions	O43424	Gene names	GRID2, GLURD2
Domain Architecture
Description	Glutamate receptor delta-2 subunit precursor (GluR delta-2).

NMDZ1_MOUSE
NC score	0.903467 (rank : 21)	θ value	1.56274e-52 (rank : 21)
Query Neighborhood Hits	46	Target Neighborhood Hits	76	Shared Neighborhood Hits	43
SwissProt Accessions	P35438, Q8CFS4	Gene names	Grin1, Glurz1
Domain Architecture
Description	Glutamate [NMDA] receptor subunit zeta 1 precursor (N-methyl-D- aspartate receptor subunit NR1).

NMDZ1_HUMAN
NC score	0.903162 (rank : 22)	θ value	4.54686e-52 (rank : 22)
Query Neighborhood Hits	46	Target Neighborhood Hits	77	Shared Neighborhood Hits	43
SwissProt Accessions	Q05586, P35437, Q12867, Q12868	Gene names	GRIN1, NMDAR1
Domain Architecture
Description	Glutamate [NMDA] receptor subunit zeta 1 precursor (N-methyl-D- aspartate receptor subunit NR1).

NMD3A_HUMAN
NC score	0.849246 (rank : 23)	θ value	3.07116e-24 (rank : 33)
Query Neighborhood Hits	46	Target Neighborhood Hits	58	Shared Neighborhood Hits	35
SwissProt Accessions	Q8TCU5, Q8TF29, Q8WXI6	Gene names	GRIN3A, KIAA1973
Domain Architecture	No domain graphic available
Description	Glutamate [NMDA] receptor subunit 3A precursor (N-methyl-D-aspartate receptor subtype NR3A) (NMDAR-L).

NMD3B_HUMAN
NC score	0.845906 (rank : 24)	θ value	4.28545e-26 (rank : 31)
Query Neighborhood Hits	46	Target Neighborhood Hits	55	Shared Neighborhood Hits	35
SwissProt Accessions	O60391, Q5EAK7, Q7RTW9	Gene names	GRIN3B
Domain Architecture	No domain graphic available
Description	Glutamate [NMDA] receptor subunit 3B precursor (N-methyl-D-aspartate receptor subtype NR3B) (NR3B) (NMDAR3B).

NMD3B_MOUSE
NC score	0.843574 (rank : 25)	θ value	2.77775e-25 (rank : 32)
Query Neighborhood Hits	46	Target Neighborhood Hits	51	Shared Neighborhood Hits	33
SwissProt Accessions	Q91ZU9, Q8VHV0	Gene names	Grin3b
Domain Architecture	No domain graphic available
Description	Glutamate [NMDA] receptor subunit 3B precursor (N-methyl-D-aspartate receptor subunit NR3B) (NR3B) (NMDAR3B) (NMDA receptor NR4) (Nr4).

NMDE4_HUMAN
NC score	0.828064 (rank : 26)	θ value	1.12514e-34 (rank : 25)
Query Neighborhood Hits	46	Target Neighborhood Hits	133	Shared Neighborhood Hits	34
SwissProt Accessions	O15399	Gene names	GRIN2D
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 4 precursor (N-methyl D- aspartate receptor subtype 2D) (NR2D) (NMDAR2D) (EB11).

NMDE4_MOUSE
NC score	0.825882 (rank : 27)	θ value	1.12514e-34 (rank : 26)
Query Neighborhood Hits	46	Target Neighborhood Hits	158	Shared Neighborhood Hits	34
SwissProt Accessions	Q03391	Gene names	Grin2d
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 4 precursor (N-methyl D- aspartate receptor subtype 2D) (NR2D) (NMDAR2D).

NMDE3_MOUSE
NC score	0.823029 (rank : 28)	θ value	2.34606e-32 (rank : 29)
Query Neighborhood Hits	46	Target Neighborhood Hits	86	Shared Neighborhood Hits	34
SwissProt Accessions	Q01098	Gene names	Grin2c
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 3 precursor (N-methyl D- aspartate receptor subtype 2C) (NR2C) (NMDAR2C).

NMDE2_MOUSE
NC score	0.822517 (rank : 29)	θ value	1.12514e-34 (rank : 24)
Query Neighborhood Hits	46	Target Neighborhood Hits	64	Shared Neighborhood Hits	36
SwissProt Accessions	Q01097, Q9DCB2	Gene names	Grin2b
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 2 precursor (N-methyl D- aspartate receptor subtype 2B) (NR2B) (NMDAR2B).

NMDE2_HUMAN
NC score	0.822514 (rank : 30)	θ value	1.12514e-34 (rank : 23)
Query Neighborhood Hits	46	Target Neighborhood Hits	65	Shared Neighborhood Hits	36
SwissProt Accessions	Q13224, Q12919, Q13220, Q13225, Q9UM56	Gene names	GRIN2B
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 2 precursor (N-methyl D- aspartate receptor subtype 2B) (NR2B) (NMDAR2B) (N-methyl-D-aspartate receptor subunit 3) (NR3) (hNR3).

NMDE3_HUMAN
NC score	0.821361 (rank : 31)	θ value	8.91499e-32 (rank : 30)
Query Neighborhood Hits	46	Target Neighborhood Hits	110	Shared Neighborhood Hits	34
SwissProt Accessions	Q14957	Gene names	GRIN2C
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 3 precursor (N-methyl D- aspartate receptor subtype 2C) (NR2C) (NMDAR2C).

NMDE1_MOUSE
NC score	0.818341 (rank : 32)	θ value	1.37539e-32 (rank : 28)
Query Neighborhood Hits	46	Target Neighborhood Hits	84	Shared Neighborhood Hits	34
SwissProt Accessions	P35436	Gene names	Grin2a
Domain Architecture	No domain graphic available
Description	Glutamate [NMDA] receptor subunit epsilon 1 precursor (N-methyl D- aspartate receptor subtype 2A) (NR2A) (NMDAR2A).

NMDE1_HUMAN
NC score	0.818234 (rank : 33)	θ value	1.37539e-32 (rank : 27)
Query Neighborhood Hits	46	Target Neighborhood Hits	81	Shared Neighborhood Hits	33
SwissProt Accessions	Q12879, O00669	Gene names	GRIN2A
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 1 precursor (N-methyl D- aspartate receptor subtype 2A) (NR2A) (NMDAR2A) (hNR2A).

TS1R2_MOUSE
NC score	0.075841 (rank : 34)	θ value	0.0563607 (rank : 40)
Query Neighborhood Hits	46	Target Neighborhood Hits	69	Shared Neighborhood Hits	18
SwissProt Accessions	Q925I4, Q923J8	Gene names	Tas1r2, Gpr71, T1r2, Tr2
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 2 precursor (G-protein coupled receptor 71) (Sweet taste receptor T1R2).

CASR_HUMAN
NC score	0.074461 (rank : 35)	θ value	0.00665767 (rank : 37)
Query Neighborhood Hits	46	Target Neighborhood Hits	71	Shared Neighborhood Hits	13
SwissProt Accessions	P41180, Q13912, Q16108, Q16109, Q16110, Q16379, Q4PJ19	Gene names	CASR, GPRC2A, PCAR1
Domain Architecture
Description	Extracellular calcium-sensing receptor precursor (CaSR) (Parathyroid Cell calcium-sensing receptor).

CASR_MOUSE
NC score	0.074428 (rank : 36)	θ value	0.00665767 (rank : 38)
Query Neighborhood Hits	46	Target Neighborhood Hits	72	Shared Neighborhood Hits	13
SwissProt Accessions	Q9QY96, O08968, O88519, Q9QY95, Q9QZU8, Q9R1D6, Q9R1Y2	Gene names	Casr, Gprc2a
Domain Architecture
Description	Extracellular calcium-sensing receptor precursor (CaSR) (Parathyroid Cell calcium-sensing receptor).

MGR5_HUMAN
NC score	0.070171 (rank : 37)	θ value	0.00390308 (rank : 36)
Query Neighborhood Hits	46	Target Neighborhood Hits	72	Shared Neighborhood Hits	20
SwissProt Accessions	P41594	Gene names	GRM5, GPRC1E, MGLUR5
Domain Architecture
Description	Metabotropic glutamate receptor 5 precursor (mGluR5).

GABR1_HUMAN
NC score	0.069648 (rank : 38)	θ value	θ > 10 (rank : 48)
Query Neighborhood Hits	46	Target Neighborhood Hits	142	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UBS5, O95375, O95468, O95975, O96022, Q86W60, Q9UQQ0	Gene names	GABBR1, GPRC3A
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 1 precursor (GABA-B receptor 1) (GABA-B-R1) (Gb1).

GABR1_MOUSE
NC score	0.069528 (rank : 39)	θ value	θ > 10 (rank : 49)
Query Neighborhood Hits	46	Target Neighborhood Hits	139	Shared Neighborhood Hits	23
SwissProt Accessions	Q9WV18, Q9WU48, Q9WV15, Q9WV16, Q9WV17	Gene names	Gabbr1
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 1 precursor (GABA-B receptor 1) (GABA-B-R1) (Gb1).

MGR1_MOUSE
NC score	0.068897 (rank : 40)	θ value	0.00228821 (rank : 35)
Query Neighborhood Hits	46	Target Neighborhood Hits	90	Shared Neighborhood Hits	20
SwissProt Accessions	P97772, Q6AXG4, Q9EPV6	Gene names	Grm1, Gprc1a, Mglur1
Domain Architecture
Description	Metabotropic glutamate receptor 1 precursor (mGluR1).

MGR1_HUMAN
NC score	0.068881 (rank : 41)	θ value	0.00228821 (rank : 34)
Query Neighborhood Hits	46	Target Neighborhood Hits	85	Shared Neighborhood Hits	20
SwissProt Accessions	Q13255, Q13256, Q14757, Q14758, Q5VTF7, Q5VTF8, Q9NU10, Q9UGS9, Q9UGT0	Gene names	GRM1, GPRC1A, MGLUR1
Domain Architecture
Description	Metabotropic glutamate receptor 1 precursor (mGluR1).

TS1R1_MOUSE
NC score	0.067039 (rank : 42)	θ value	6.88961 (rank : 44)
Query Neighborhood Hits	46	Target Neighborhood Hits	57	Shared Neighborhood Hits	19
SwissProt Accessions	Q99PG6, Q6NS58, Q923J9, Q925I5, Q99PG5	Gene names	Tas1r1, Gpr70, T1r1, Tr1
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 1 precursor (G-protein coupled receptor 70).

TS1R2_HUMAN
NC score	0.064529 (rank : 43)	θ value	0.0431538 (rank : 39)
Query Neighborhood Hits	46	Target Neighborhood Hits	48	Shared Neighborhood Hits	15
SwissProt Accessions	Q8TE23, Q5TZ19	Gene names	TAS1R2, GPR71, T1R2, TR2
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 2 precursor (G-protein coupled receptor 71) (Sweet taste receptor T1R2).

ERB1_HUMAN
NC score	0.051029 (rank : 44)	θ value	θ > 10 (rank : 47)
Query Neighborhood Hits	46	Target Neighborhood Hits	23	Shared Neighborhood Hits	8
SwissProt Accessions	P60509	Gene names
Domain Architecture	No domain graphic available
Description	HERV-R(b)_3p24.3 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (HERV-R(b) Env protein) [Includes: Surface protein domain (SU); Transmembrane protein domain (TM)].

ANPRC_MOUSE
NC score	0.037689 (rank : 45)	θ value	3.0926 (rank : 41)
Query Neighborhood Hits	46	Target Neighborhood Hits	27	Shared Neighborhood Hits	10
SwissProt Accessions	P70180, P97804, Q9R025, Q9R027, Q9R028	Gene names	Npr3
Domain Architecture
Description	Atrial natriuretic peptide clearance receptor precursor (ANP-C) (ANPRC) (NPR-C) (Atrial natriuretic peptide C-type receptor) (EF-2).

ANPRC_HUMAN
NC score	0.037372 (rank : 46)	θ value	6.88961 (rank : 42)
Query Neighborhood Hits	46	Target Neighborhood Hits	27	Shared Neighborhood Hits	10
SwissProt Accessions	P17342	Gene names	NPR3, ANPRC
Domain Architecture
Description	Atrial natriuretic peptide clearance receptor precursor (ANP-C) (ANPRC) (NPR-C) (Atrial natriuretic peptide C-type receptor).

TOPB1_MOUSE
NC score	0.006395 (rank : 47)	θ value	8.99809 (rank : 46)
Query Neighborhood Hits	46	Target Neighborhood Hits	89	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZQF0, Q6P6P0, Q80Y33, Q8BUI0, Q8BUK1, Q8R348, Q91VX3, Q922X8	Gene names	Topbp1, Kiaa0259
Domain Architecture	No domain graphic available
Description	DNA topoisomerase II-binding protein 1 (DNA topoisomerase IIbeta- binding protein 1) (TopBP1).

FBXW5_MOUSE
NC score	0.004487 (rank : 48)	θ value	6.88961 (rank : 43)
Query Neighborhood Hits	46	Target Neighborhood Hits	159	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QXW2	Gene names	Fbxw5, Fbw5
Domain Architecture
Description	F-box/WD repeat protein 5 (F-box and WD-40 domain protein 5).

DCAK2_HUMAN
NC score	-0.004944 (rank : 49)	θ value	8.99809 (rank : 45)
Query Neighborhood Hits	46	Target Neighborhood Hits	862	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N568, Q8N399	Gene names	DCAMKL2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase DCAMKL2 (EC 2.7.11.1) (Doublecortin- like and CAM kinase-like 2).